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Ellen van der Voort

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Wanda G H Han; Ellen I H van der Voort; Hanane el Bannoudi; Pascale Louis-Plence; Tom W J Huizinga; René E M Toes
DX5(+)CD4(+) T cells modulate cytokine production by CD4(+) T cells towards IL-10 via the production of IL-4.
Diane van der Woude; Silje W Syversen; Ellen I H van der Voort; Kirsten N Verpoort; Guro L Goll; Michael P M van der Linden; Annette H M Van Der Helm-Van Mil; Désirée M F M van der Heijde; Tom W J Huizinga; Tore K Kvien; René E M Toes
The ACPA isotype profile reflects long-term radiographic progression in rheumatoid arthritis.
A J M Schuerwegh; A Ioan-Facsinay; A L Dorjée; J Roos; I M Bajema; Ellen I H van der Voort; T W J Huizinga; René E M Toes
Evidence for a functional role of IgE anticitrullinated protein antibodies in rheumatoid arthritis.

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All Publications

2010: Wanda G H Han; Ellen I H van der Voort; Hanane el Bannoudi; Pascale Louis-Plence; Tom W J Huizinga; René E M Toes
DX5(+)CD4(+) T cells modulate cytokine production by CD4(+) T cells towards IL-10 via the production of IL-4.
European journal of immunology 2010;40(10):2731-40.
2010: Diane van der Woude; Silje W Syversen; Ellen I H van der Voort; Kirsten N Verpoort; Guro L Goll; Michael P M van der Linden; Annette H M Van Der Helm-Van Mil; Désirée M F M van der Heijde; Tom W J Huizinga; Tore K Kvien; René E M Toes
The ACPA isotype profile reflects long-term radiographic progression in rheumatoid arthritis.
Annals of the rheumatic diseases 2010;69(6):1110-6.
2010: A J M Schuerwegh; A Ioan-Facsinay; A L Dorjée; J Roos; I M Bajema; Ellen I H van der Voort; T W J Huizinga; René E M Toes
Evidence for a functional role of IgE anticitrullinated protein antibodies in rheumatoid arthritis.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(6):2586-91.
2010: Anouk L Feitsma; Ellen I H van der Voort; Kees L M C Franken; Hanane el Bannoudi; Berendina G Elferink; Jan Wouter Drijfhout; Tom W J Huizinga; René R P De Vries; René E M Toes; A Ioan-Facsinay
Identification of citrullinated vimentin peptides as T cell epitopes in HLA-DR4-positive patients with rheumatoid arthritis.
Arthritis and rheumatism 2010;62(1):117-25.
2007: Leonie van Duivenvoorde; Wanda G H Han; Aleida M Bakker; Pascale Louis-Plence; Louis-Marie Charbonnier; Florence Apparailly; Ellen I H van der Voort; Christian Jorgensen; Tom W J Huizinga; René E M Toes
Immunomodulatory dendritic cells inhibit Th1 responses and arthritis via different mechanisms.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(3):1506-15.
2007: Nadine van Montfoort; Judith M H de Jong; Danita Schuurhuis; Ellen I H van der Voort; Marcel Camps; Tom W J Huizinga; Cees van Kooten; Mohamed R Daha; Sjef Verbeek; Ferry Ossendorp; René E M Toes
A novel role of complement factor C1q in augmenting the presentation of antigen captured in immune complexes to CD8+ T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(12):7581-6.
2007: Jun Wang; Andreea Ioan-Facsinay; Ellen I H van der Voort; Tom W J Huizinga; René E M Toes
Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells.
European journal of immunology 2007;37(1):129-38.
2006: Judith M H de Jong; Danita Schuurhuis; Andreea Ioan-Facsinay; Mick Welling; Marcel Camps; Ellen I H van der Voort; Tom W J Huizinga; Ferry Ossendorp; Sjef Verbeek; René E M Toes
Dendritic cells, but not macrophages or B cells, activate major histocompatibility complex class II-restricted CD4+ T cells upon immune-complex uptake in vivo.
Immunology 2006;119(4):499-506.
2006: Martine Ossevoort; Arnaud Zaldumbide; Steve J Cramer; Ellen I H van der Voort; René E M Toes; Rob Hoeben
Characterization of an immuno 'stealth' derivative of the herpes simplex virus thymidine-kinase gene.
Cancer gene therapy 2006;13(6):584-91.
2006: Judith M H de Jong; Danita Schuurhuis; Andreea Ioan-Facsinay; Ellen I H van der Voort; Tom W J Huizinga; Ferry Ossendorp; René E M Toes; Sjef Verbeek
Murine Fc receptors for IgG are redundant in facilitating presentation of immune complex derived antigen to CD8+ T cells in vivo.
Molecular immunology 2006;43(13):2045-50.
2005: Roelof Flierman; Hendrik J Witteveen; Ellen I H van der Voort; Tom W J Huizinga; René R P De Vries; Willem E Fibbe; René E M Toes; Jacob M van Laar
Control of systemic B cell-mediated autoimmune disease by nonmyeloablative conditioning and major histocompatibility complex-mismatched allogeneic bone marrow transplantation.
Blood 2005;105(7):2991-4.
2004: Jolanda H M van Bilsen; Henrike van Dongen; Leroy R Lard; Ellen I H van der Voort; Diënne G Elferink; Aleida M Bakker; André M M Miltenburg; Tom W J Huizinga; René R P De Vries; René E M Toes
Functional regulatory immune responses against human cartilage glycoprotein-39 in health vs. proinflammatory responses in rheumatoid arthritis.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(49):17180-5.
2004: Geertje J D van Mierlo; Zita F H M Boonman; Hélène M H Dumortier; Annemieke Th den Boer; Marieke F Fransen; Jan Nouta; Ellen I H van der Voort; Rienk Offringa; René E M Toes; Cornelis J M Melief
Activation of dendritic cells that cross-present tumor-derived antigen licenses CD8+ CTL to cause tumor eradication.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(11):6753-9.
2004: Leonie van Duivenvoorde; Pascale Louis-Plence; Florence Apparailly; Ellen I H van der Voort; Tom W J Huizinga; Christian Jorgensen; René E M Toes
Antigen-specific immunomodulation of collagen-induced arthritis with tumor necrosis factor-stimulated dendritic cells.
Arthritis and rheumatism 2004;50(10):3354-64.
2003: Martine Ossevoort; B M J Visser; Diana J M van den Wollenberg; Ellen I H van der Voort; R Offringa; Cornelis J M Melief; René E M Toes; Rob Hoeben
Creation of immune 'stealth' genes for gene therapy through fusion with the Gly-Ala repeat of EBNA-1.
Gene therapy 2003;10(24):2020-8.
2002: Geertje J D van Mierlo; Annemieke Th den Boer; Jan Paul Medema; Ellen I H van der Voort; Marieke F Fransen; Rienk Offringa; Cornelis J M Melief; René E M Toes
CD40 stimulation leads to effective therapy of CD40(-) tumors through induction of strong systemic cytotoxic T lymphocyte immunity.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5561-6.
2002: Linda Diehl; Geertje J D van Mierlo; Annemieke Th den Boer; Ellen I H van der Voort; Marieke F Fransen; Liesbeth van Bostelen; Paul Krimpenfort; Cornelis J M Melief; Robert S Mittler; René E M Toes; Rienk Offringa
In vivo triggering through 4-1BB enables Th-independent priming of CTL in the presence of an intact CD28 costimulatory pathway.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):3755-62.
2001: Lucas R H M Schurmans; Linda Diehl; Annemieke Th den Boer; Roger P M Sutmuller; Zita F H M Boonman; Jan Paul Medema; Ellen I H van der Voort; J Laman; Cornelis J M Melief; Martine J Jager; René E M Toes
Rejection of intraocular tumors by CD4(+) T cells without induction of phthisis.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(10):5832-7.
2001: Annemieke Th den Boer; Linda Diehl; Geertje J D van Mierlo; Ellen I H van der Voort; Marieke F Fransen; Paul Krimpenfort; Cornelis J M Melief; Rienk Offringa; René E M Toes
Longevity of antigen presentation and activation status of APC are decisive factors in the balance between CTL immunity versus tolerance.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(5):2522-8.
2000: Roger P M Sutmuller; Lucas R H M Schurmans; Leonie van Duivenvoorde; J A Tine; Ellen I H van der Voort; René E M Toes; Cornelis J M Melief; Martine J Jager; Rienk Offringa
Adoptive T cell immunotherapy of human uveal melanoma targeting gp100.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(12):7308-15.
2000: Danita Schuurhuis; Sandra Laban; René E M Toes; Paola Ricciardi-Castagnoli; Monique J Kleijmeer; Ellen I H van der Voort; Delphine Rea; Rienk Offringa; H J Geuze; Cornelis J M Melief; Ferry Ossendorp
Immature dendritic cells acquire CD8(+) cytotoxic T lymphocyte priming capacity upon activation by T helper cell-independent or -dependent stimuli.
The Journal of experimental medicine 2000;192(1):145-50.
2000: Linda Diehl; Annemieke Th den Boer; Ellen I H van der Voort; Cornelis J M Melief; Rienk Offringa; René E M Toes
The role of CD40 in peripheral T cell tolerance and immunity.
Journal of molecular medicine (Berlin, Germany) 2000;78(7):363-71.
1999: Lucas R H M Schurmans; Annemieke Th den Boer; Linda Diehl; Ellen I H van der Voort; W Martin Kast; Cornelis J M Melief; René E M Toes; Martine J Jager
Successful immunotherapy of an intraocular tumor in mice.
Cancer research 1999;59(20):5250-4.
1999: Linda Diehl; Annemieke Th den Boer; Stephen P Schoenberger; Ellen I H van der Voort; Schumacher Ton; Cornelis J M Melief; Rienk Offringa; René E M Toes
CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy.
Nature medicine 1999;5(7):774-9.
1998: René E M Toes; Stephen P Schoenberger; Ellen I H van der Voort; Rienk Offringa; Cornelis J M Melief
CD40-CD40Ligand interactions and their role in cytotoxic T lymphocyte priming and anti-tumor immunity.
Seminars in immunology 1998;10(6):443-8.
1998: Stephen P Schoenberger; Ellen I H van der Voort; G M Krietemeijer; Rienk Offringa; Cornelis J M Melief; René E M Toes
Cross-priming of CTL responses in vivo does not require antigenic peptides in the endoplasmic reticulum of immunizing cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(8):3808-12.
1998: Stephen P Schoenberger; René E M Toes; Ellen I H van der Voort; Rienk Offringa; Cornelis J M Melief
T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions.
Nature 1998;393(6684):480-3.
1998: René E M Toes; Ellen I H van der Voort; Stephen P Schoenberger; Jan Wouter Drijfhout; Louis van Bloois; G Storm; W Martin Kast; Rienk Offringa; Cornelis J M Melief
Enhancement of tumor outgrowth through CTL tolerization after peptide vaccination is avoided by peptide presentation on dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(9):4449-56.
1997: René E M Toes; Rob Hoeben; Ellen I H van der Voort; Maaike E Ressing; A J van der Eb; Cornelis J M Melief; Rienk Offringa
Protective anti-tumor immunity induced by vaccination with recombinant adenoviruses encoding multiple tumor-associated cytotoxic T lymphocyte epitopes in a string-of-beads fashion.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14660-5.
1997: René E M Toes; Stephen P Schoenberger; Ellen I H van der Voort; W Martin Kast; Rob Hoeben; Cornelis J M Melief; Rienk Offringa
Activation or frustration of anti-tumor responses by T-cell-based immune modulation.
Seminars in immunology 1997;9(5):323-7.
1997: MJ Visseren; Sjoerd H van der burg; Ellen I H van der Voort; RM Brandt; Peter I Schrier; P van der Bruggen; T Boon; Cornelis J M Melief; W Martin Kast
Identification of HLA-A*0201-restricted CTL epitopes encoded by the tumor-specific MAGE-2 gene product.
International journal of cancer. Journal international du cancer 1997;73(1):125-30.
1997: MJ Visseren; Sjoerd H van der burg; GE Hawes; Ellen I H van der Voort; Peter J van den Elsen; Cornelis J M Melief
Affinity, specificity and T-cell-receptor diversity of melanoma-specific CTL generated in vitro against a single tyrosinase epitope.
International journal of cancer. Journal international du cancer 1997;72(6):1122-8.
1997: Michel P M Vierboom; H W Nijman; Rienk Offringa; Ellen I H van der Voort; Thorbald van Hall; L van den Broek; Gert Jan Fleuren; P Kenemans; W M Kast; Cornelis J M Melief
Tumor eradication by wild-type p53-specific cytotoxic T lymphocytes.
The Journal of experimental medicine 1997;186(5):695-704.
1996: E Hooijberg; M J Visseren; Paul van den Berk; A P Jellema; P Romeijn; J J Sein; Ellen I H van der Voort; A Hekman; Ferry Ossendorp; Cornelis J M Melief
Lysis of syngeneic tumor B cells by autoreactive cytotoxic T lymphocytes specific for a CD19 antigen-derived synthetic peptide.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1996;19(5):346-56.
1996: René E M Toes; R J Blom; Ellen I H van der Voort; Rienk Offringa; Cornelis J M Melief; W Martin Kast
Protective antitumor immunity induced by immunization with completely allogeneic tumor cells.
Cancer research 1996;56(16):3782-7.
1995: M J Visseren; A van Elsas; Ellen I H van der Voort; Maaike E Ressing; W Martin Kast; Peter I Schrier; Cornelis J M Melief
CTL specific for the tyrosinase autoantigen can be induced from healthy donor blood to lyse melanoma cells.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(8):3991-8.
1994: M J Visseren; M Koot; Ellen I H van der Voort; L A Gravestein; H J Schoenmakers; W Martin Kast; M Zijlstra; Cornelis J M Melief
Production of interleukin-2 by EL4 tumor cells induces natural killer cell- and T-cell-mediated immunity.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1994;15(2):119-28.