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Jan van Deursen

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Robin M Ricke; Jan M A van Deursen
Aneuploidy in health, disease, and aging.
Darren J Baker; Atta Behfar; Ruben Crespo-Diaz; Meelad M Dawlaty; Karthik B Jeganathan; Liviu Malureanu; Santiago Reyes; Lauren Seaburg; Virginia Shapiro; Andre Terzic; Bart van De Sluis; Janine H van Ree; Tobias Wijshake; Jan M A van Deursen
Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan.
R M Naylor; Darren J Baker; Jan M A van Deursen
Senescent cells: a novel therapeutic target for aging and age-related diseases.

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All Publications

2013: Robin M Ricke; Jan M A van Deursen
Aneuploidy in health, disease, and aging.
The Journal of cell biology 2013;201(1):11-21.
2013: Darren J Baker; Atta Behfar; Ruben Crespo-Diaz; Meelad M Dawlaty; Karthik B Jeganathan; Liviu Malureanu; Santiago Reyes; Lauren Seaburg; Virginia Shapiro; Andre Terzic; Bart van De Sluis; Janine H van Ree; Tobias Wijshake; Jan M A van Deursen
Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan.
Nature cell biology 2013;15(1):96-102.
2013: R M Naylor; Darren J Baker; Jan M A van Deursen
Senescent cells: a novel therapeutic target for aging and age-related diseases.
Clinical pharmacology and therapeutics 2013;93(1):105-16.
2012: Robin M Ricke; Andrew M Harrison; Karthik B Jeganathan; Liviu Malureanu; Jan M A van Deursen
Bub1 kinase activity drives error correction and mitotic checkpoint control but not tumor suppression.
The Journal of cell biology 2012;199(6):931-49.
2012: Tobias Wijshake; Darren J Baker; Karthik B Jeganathan; Liviu A Malureanu; Bart van De Sluis; Jan M A van Deursen
Reduced life- and healthspan in mice carrying a mono-allelic BubR1 MVA mutation.
PLoS genetics 2012;8(12):e1003138.
2011: Masakazu Hamada; Karthik B Jeganathan; Jomon Joseph; Ralph H Kehlenbach; Liviu Malureanu; Janine H van Ree; Sarah Wälde; Anna Haeger; Jan M A van Deursen
Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.
The Journal of cell biology 2011;194(4):597-612.
2011: Robin M Ricke; Karthik B Jeganathan; Jan M A van Deursen
Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation.
The Journal of cell biology 2011;193(6):1049-64.
2010: Liviu Malureanu; Karthik B Jeganathan; Fang Jin; Darren J Baker; Janine H van Ree; Oliver Gullon; Zheyan Chen; John R Henley; Jan M A van Deursen
Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis.
The Journal of cell biology 2010;191(2):313-29.
2010: Fang Jin; Masakazu Hamada; Liviu Malureanu; Karthik B Jeganathan; Wei Zhou; Dean E Morbeck; Jan M A van Deursen
Cdc20 is critical for meiosis I and fertility of female mice.
PLoS genetics 2010;6(9):.
2010: S Hussain; O Foreman; S L Perkins; Thomas E Witzig; R R Miles; Jan M A van Deursen; P J Galardy
The de-ubiquitinase UCH-L1 is an oncogene that drives the development of lymphoma in vivo by deregulating PHLPP1 and Akt signaling.
Leukemia 2010;24(9):1641-55.
2010: Shariq S Khwaja; Hudan Liu; Caili Tong; Fang Jin; Warren S Pear; Jan M A van Deursen; Richard J Bram
HIV-1 Rev-binding protein accelerates cellular uptake of iron to drive Notch-induced T cell leukemogenesis in mice.
The Journal of clinical investigation 2010;120(7):2537-48.
2010: Darren J Baker; Jan M A van Deursen
Chromosome missegregation causes colon cancer by APC loss of heterozygosity.
Cell cycle (Georgetown, Tex.) 2010;9(9):1711-6.
2010: Janine H van Ree; Karthik B Jeganathan; Liviu Malureanu; Jan M A van Deursen
Overexpression of the E2 ubiquitin-conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation.
The Journal of cell biology 2010;188(1):83-100.
2009: Darren J Baker; Fang Jin; Karthik B Jeganathan; Jan M A van Deursen
Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosity.
Cancer cell 2009;16(6):475-86.
2009: Tomofusa Fukuyama; Lawryn H Kasper; Fayçal Boussouar; Trushar Jeevan; Jan M A van Deursen; Paul K Brindle
Histone acetyltransferase CBP is vital to demarcate conventional and innate CD8+ T-cell development.
Molecular and cellular biology 2009;29(14):3894-904.
2009: Yu Liu; Liviu Malureanu; Karthik B Jeganathan; David Dinh Tran; Lonn D Lindquist; Jan M A van Deursen; Richard J Bram
CAML loss causes anaphase failure and chromosome missegregation.
Cell cycle (Georgetown, Tex.) 2009;8(6):940-9.
2009: Gefeng Zhu; Mathew M Augustine; Takeshi Azuma; Liqun Luo; SHENG YAO; Sudarshan Anand; A Cecilia Rietz; Jiaqiang Huang; Haiying Xu; Andrew S Flies; Sarah J Flies; Koji Tamada; Marco COLONna; Jan M A van Deursen; Lieping Chen
B7-H4-deficient mice display augmented neutrophil-mediated innate immunity.
Blood 2009;113(8):1759-67.
2009: Liviu A Malureanu; Karthik B Jeganathan; Masakazu Hamada; Lisa Wasilewski; James Davenport; Jan M A van Deursen
BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/C(Cdc20) in interphase.
Developmental cell 2009;16(1):118-31.
2008: Papia Chakraborty; Yaming Wang; Jen-Hsuan Wei; Jan M A van Deursen; Hongtao Yu; Liviu Malureanu; Mary Dasso; Douglass J Forbes; David E Levy; Joachim Seemann; Beatriz M A Fontoura
Nucleoporin levels regulate cell cycle progression and phase-specific gene expression.
Developmental cell 2008;15(5):657-67.
2008: Darren J Baker; Fang Jin; Jan M A van Deursen
The yin and yang of the Cdkn2a locus in senescence and aging.
Cell cycle (Georgetown, Tex.) 2008;7(18):2795-802.
2008: Zheng Fu; Liviu Malureanu; Jun Huang; Wei Wang; Hao Li; Jan M A van Deursen; Donald J Tindall; Junjie Chen
Plk1-dependent phosphorylation of FoxM1 regulates a transcriptional programme required for mitotic progression.
Nature cell biology 2008;10(9):1076-82.
2008: Robin M Ricke; Janine H van Ree; Jan M A van Deursen
Whole chromosome instability and cancer: a complex relationship.
Trends in genetics : TIG 2008;24(9):457-66.
2008: Darren J Baker; Carmen Perez-Terzic; Fang Jin; Kevin Pitel; Nicolas J Niederländer; Karthik B Jeganathan; Satsuki Yamada; Santiago Reyes; Lois Rowe; H Jay Hiddinga; Norman L Eberhardt; Andre Terzic; Kevin S Pitel; Jan M A van Deursen
Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency.
Nature cell biology 2008;10(7):825-36.
2008: Meelad M Dawlaty; Liviu Malureanu; Karthik B Jeganathan; Esther Kao; Claudio Sustmann; Samuel Tahk; Ke Shuai; Rudolf Grosschedl; Jan M A van Deursen
Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.
Cell 2008;133(1):103-15.
2007: Karthik B Jeganathan; Liviu Malureanu; Darren J Baker; Susan C Abraham; Jan M A van Deursen
Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis.
The Journal of cell biology 2007;179(2):255-67.
2007: Darren J Baker; M M Dawlaty; P Galardy; Jan M A van Deursen
Mitotic regulation of the anaphase-promoting complex.
Cellular and molecular life sciences : CMLS 2007;64(5):589-600.
2007: Jan M A van Deursen
Rb loss causes cancer by driving mitosis mad.
Cancer cell 2007;11(1):1-3.
2006: Meelad M Dawlaty; Jan M A van Deursen
Gene targeting methods for studying nuclear transport factors in mice.
Methods (San Diego, Calif.) 2006;39(4):370-8.
2006: Karthik B Jeganathan; Jan M A van Deursen
Differential mitotic checkpoint protein requirements in somatic and germ cells.
Biochemical Society transactions 2006;34(Pt 4):583-6.
2006: Wu Xu; Tomofusa Fukuyama; Paul A Ney; Demin Wang; Jerold E Rehg; Kelli Boyd; Jan M A van Deursen; Paul K Brindle
Global transcriptional coactivators CREB-binding protein and p300 are highly essential collectively but not individually in peripheral B cells.
Blood 2006;107(11):4407-16.
2006: Darren J Baker; Karthik B Jeganathan; Liviu Malureanu; Carmen Perez-Terzic; Andre Terzic; Jan M A van Deursen
Early aging-associated phenotypes in Bub3/Rae1 haploinsufficient mice.
The Journal of cell biology 2006;172(4):529-40.
2006: Karthik B Jeganathan; Darren J Baker; Jan M A van Deursen
Securin associates with APCCdh1 in prometaphase but its destruction is delayed by Rae1 and Nup98 until the metaphase/anaphase transition.
Cell cycle (Georgetown, Tex.) 2006;5(4):366-70.
2006: Lawryn H Kasper; Tomofusa Fukuyama; Michelle A Biesen; Fayçal Boussouar; Caili Tong; Antoine de Pauw; Peter J Murray; Jan M A van Deursen; Paul K Brindle
Conditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell development.
Molecular and cellular biology 2006;26(3):789-809.
2006: Stacy L Sommer; Theresa J Berndt; Elena Frank; Jeetendra B Patel; Margaret M Redfield; Xiangyang Dong; Matthew D Griffin; Joseph P Grande; Jan M A van Deursen; Gary C Sieck; J Carlos Romero; Rajiv Kumar
Elevated blood pressure and cardiac hypertrophy after ablation of the gly96/IEX-1 gene.
Journal of applied physiology (Bethesda, Md. : 1985) 2006;100(2):707-16.
2006: Zhenkun Lou; Katherine Minter-Dykhouse; Sonia Franco; Monica Gostissa; Melissa A Rivera; Arkady Celeste; John P Manis; Jan M A van Deursen; André Nussenzweig; Tanya T Paull; Frederick W Alt; Junjie Chen
MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals.
Molecular cell 2006;21(2):187-200.
2006: Daniel B Graham; Michael P Bell; Megan M McCausland; Catherine J Huntoon; Jan M A van Deursen; William A Faubion; Shane Crotty; David J McKean
Ly9 (CD229)-deficient mice exhibit T cell defects yet do not share several phenotypic characteristics associated with SLAM- and SAP-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(1):291-300.
2005: Karthik B Jeganathan; Liviu Malureanu; Jan M A van Deursen
The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation.
Nature 2005;438(7070):1036-9.
2005: Darren J Baker; Junjie Chen; Jan M A van Deursen
The mitotic checkpoint in cancer and aging: what have mice taught us?
Current opinion in cell biology 2005;17(6):583-9.
2005: David D Tran; Contessa E Edgar; Karin L Heckman; Shari L Sutor; Catherine J Huntoon; Jan M A van Deursen; David L McKean; Richard J Bram
CAML is a p56Lck-interacting protein that is required for thymocyte development.
Immunity 2005;23(2):139-52.
2005: Xiaochun Yu; Katherine Minter-Dykhouse; Liviu Malureanu; Wei-Meng Zhao; Dongwei Zhang; Carolin J Merkle; Irene M Ward; Hideyuki Saya; Guowei Fang; Jan M A van Deursen; Junjie Chen
Chfr is required for tumor suppression and Aurora A regulation.
Nature genetics 2005;37(4):401-6.
2005: Subhash C Juneja; Jan M A van Deursen
A mouse model of familial oligoasthenoteratozoospermia.
Human reproduction (Oxford, England) 2005;20(4):881-93.
2005: Haojie Huang; Kevin M Regan; Fang Wang; Diping Wang; David I Smith; Jan M A van Deursen; Donald J Tindall
Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1649-54.
2005: Malayannan Subramaniam; Genevieve Gorny; Steven A Johnsen; David G Monroe; Glenda L Evans; Daniel G Fraser; David J Rickard; Kay Rasmussen; Jan M A van Deursen; Russell T Turner; Merry Jo Oursler; Thomas C Spelsberg
TIEG1 null mouse-derived osteoblasts are defective in mineralization and in support of osteoclast differentiation in vitro.
Molecular and cellular biology 2005;25(3):1191-9.
2004: Darren J Baker; Karthik B Jeganathan; J Douglas Cameron; Michael Thompson; Subhash Juneja; Alena Kopecka; Rajiv Kumar; Robert B Jenkins; Piet C de Groen; Patrick Roche; Jan M A van Deursen
BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice.
Nature genetics 2004;36(7):744-9.
2004: Licia Selleri; Jorge F DiMartino; Jan M A van Deursen; Andrea Brendolan; Mrinmoy Sanyal; Elles Boon; Terence D Capellini; Kevin S Smith; Joon Rhee; Heike Pöpperl; Gerard C Grosveld; Michael L Cleary
The TALE homeodomain protein Pbx2 is not essential for development and long-term survival.
Molecular and cellular biology 2004;24(12):5324-31.
2004: Abraham L Kierszenbaum; Laura L Tres; Eugene Rivkin; Ningling Kang-Decker; Jan M A van Deursen
The acroplaxome is the docking site of Golgi-derived myosin Va/Rab27a/b- containing proacrosomal vesicles in wild-type and Hrb mutant mouse spermatids.
Biology of reproduction 2004;70(5):1400-10.
2004: Haidong Dong; Gefeng Zhu; Koji Tamada; Dallas B Flies; Jan M A van Deursen; Lieping Chen
B7-H1 determines accumulation and deletion of intrahepatic CD8(+) T lymphocytes.
Immunity 2004;20(3):327-36.
2004: Cheryl A Conover; Laurie K Bale; Michael T Overgaard; Edward W Johnstone; Ulla H Laursen; Ernst-Martin Füchtbauer; Claus Oxvig; Jan M A van Deursen
Metalloproteinase pregnancy-associated plasma protein A is a critical growth regulatory factor during fetal development.
Development (Cambridge, England) 2004;131(5):1187-94.
2004: Ningling Kang-Decker; Caili Tong; Fayçal Boussouar; Darren J Baker; Wu Xu; Alexey A Leontovich; William R Taylor; Paul K Brindle; Jan M A van Deursen
Loss of CBP causes T cell lymphomagenesis in synergy with p27Kip1 insufficiency.
Cancer cell 2004;5(2):177-89.
2003: David D Tran; Helen R Russell; Shari L Sutor; Jan M A van Deursen; Richard J Bram
CAML is required for efficient EGF receptor recycling.
Developmental cell 2003;5(2):245-56.
2003: Irene M Ward; Kay Minn; Jan M A van Deursen; Junjie Chen
p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice.
Molecular and cellular biology 2003;23(7):2556-63.
2003: Carmen Perez-Terzic; Atta Behfar; Annabelle Méry; Jan M A van Deursen; Andre Terzic; Michel Pucéat
Structural adaptation of the nuclear pore complex in stem cell-derived cardiomyocytes.
Circulation research 2003;92(4):444-52.
2003: J Ramesh Babu; Karthik B Jeganathan; Darren J Baker; Xiaosheng Wu; Ningling Kang-Decker; Jan M A van Deursen
Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation.
The Journal of cell biology 2003;160(3):341-53.
2003: Song-Tao Liu; Jan M A van Deursen; Tim J Yen
The role of mitotic checkpoint in maintaining genomic stability.
Current topics in developmental biology 2003;58():27-51.
2003: Jan M A van Deursen
Gene targeting in mouse embryonic stem cells.
Methods in molecular biology (Clifton, N.J.) 2003;209():145-58.
2002: Lawryn H Kasper; Fayçal Boussouar; Paul A Ney; Carl W Jackson; Jerold E Rehg; Jan M A van Deursen; Paul K Brindle
A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis.
Nature 2002;419(6908):738-43.
2002: Koji Tamada; Jian Ni; Gefeng Zhu; Michele Fiscella; Baiqin Teng; Jan M A van Deursen; Lieping Chen
Cutting edge: selective impairment of CD8+ T cell function in mice lacking the TNF superfamily member LIGHT.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(10):4832-5.
2001: Ningling Kang-Decker; G T Mantchev; S C Juneja; Mark A McNiven; Jan M A van Deursen
Lack of acrosome formation in Hrb-deficient mice.
Science (New York, N.Y.) 2001;294(5546):1531-3.
2001: X Wang; J Ramesh Babu; J M Harden; Sandra A Jablonski; M H Gazi; Wilma L Lingle; Piet C de Groen; Tim J Yen; Jan M A van Deursen
The mitotic checkpoint protein hBUB3 and the mRNA export factor hRAE1 interact with GLE2p-binding sequence (GLEBS)-containing proteins.
The Journal of biological chemistry 2001;276(28):26559-67.
2001: GU von Bülow; Jan M A van Deursen; RJ Bram
Regulation of the T-independent humoral response by TACI.
Immunity 2001;14(5):573-82.
2001: X Wu; Lawryn H Kasper; R T Mantcheva; G T Mantchev; M J Springett; Jan M A van Deursen
Disruption of the FG nucleoporin NUP98 causes selective changes in nuclear pore complex stoichiometry and function.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3191-6.
2000: Frederique Zindy; Jan M A van Deursen; Gerard C Grosveld; Charles J Sherr; Martine F Roussel
INK4d-deficient mice are fertile despite testicular atrophy.
Molecular and cellular biology 2000;20(1):372-8.
1999: M P Brown; T Nosaka; Ralph A Tripp; J Brooks; Jan M A van Deursen; M K Brenner; Peter C Doherty; James N Ihle
Reconstitution of early lymphoid proliferation and immune function in Jak3-deficient mice by interleukin-3.
Blood 1999;94(6):1906-14.
1999: C E Pritchard; Maarten Fornerod; Lawryn H Kasper; Jan M A van Deursen
RAE1 is a shuttling mRNA export factor that binds to a GLEBS-like NUP98 motif at the nuclear pore complex through multiple domains.
The Journal of cell biology 1999;145(2):237-54.
1999: Richard Moriggl; David J Topham; S Teglund; Veronika Sexl; Catriona McKay; Denan Wang; Angelika Hoffmeyer; Jan M A van Deursen; Mark Y Sangster; Kevin D Bunting; Gerard C Grosveld; James N Ihle
Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells.
Immunity 1999;10(2):249-59.
1999: Lawryn H Kasper; Paul K Brindle; Catherine A Schnabel; C E Pritchard; Michael L Cleary; Jan M A van Deursen
CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity.
Molecular and cellular biology 1999;19(1):764-76.
1998: S Teglund; Catriona McKay; E Schuetz; Jan M A van Deursen; D Stravopodis; Denan Wang; M Brown; S Bodner; Gerard C Grosveld; James N Ihle
Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses.
Cell 1998;93(5):841-50.
1998: Evan Parganas; Denan Wang; D Stravopodis; David J Topham; Jean-Christophe Marine; S Teglund; E F Vanin; S Bodner; Oscar R Colamonici; Jan M A van Deursen; Gerard C Grosveld; James N Ihle
Jak2 is essential for signaling through a variety of cytokine receptors.
Cell 1998;93(3):385-95.
1998: F Martin; Jan M A van Deursen; Ramesh A Shivdasani; Carl W Jackson; A G Troutman; Paul A Ney
Erythroid maturation and globin gene expression in mice with combined deficiency of NF-E2 and nrf-2.
Blood 1998;91(9):3459-66.
1997: JM Boer; Jan M A van Deursen; Huib Croes; Jack Fransen; Gerard C Grosveld
The nucleoporin CAN/Nup214 binds to both the cytoplasmic and the nucleoplasmic sides of the nuclear pore complex in overexpressing cells.
Experimental cell research 1997;232(1):182-5.
1997: Maarten Fornerod; Jan M A van Deursen; Sjozef van Baal; A Reynolds; D Davis; K G Murti; J Fransen; Gerard C Grosveld
The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88.
The EMBO journal 1997;16(4):807-16.
1996: Jan M A van Deursen; J Boer; Lawryn H Kasper; Gerard C Grosveld
G2 arrest and impaired nucleocytoplasmic transport in mouse embryos lacking the proto-oncogene CAN/Nup214.
The EMBO journal 1996;15(20):5574-83.
1996: William E Thierfelder; Jan M A van Deursen; K Yamamoto; Ralph A Tripp; S R Sarawar; RT Carson; Mark Y Sangster; Dario A A Vignali; Peter C Doherty; Gerard C Grosveld; James N Ihle
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells.
Nature 1996;382(6587):171-4.
1996: K Shimoda; Jan M A van Deursen; Mark Y Sangster; S R Sarawar; RT Carson; Ralph A Tripp; C Chu; F W Quelle; T Nosaka; Dario A A Vignali; Peter C Doherty; Gerard C Grosveld; William Paul; James N Ihle
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene.
Nature 1996;380(6575):630-3.
1996: T Okuda; Jan M A van Deursen; S W Hiebert; Gerard C Grosveld; James R Downing
AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis.
Cell 1996;84(2):321-30.
1995: T Nosaka; Jan M A van Deursen; Ralph A Tripp; William E Thierfelder; bruce witthuhn; A P McMickle; Peter C Doherty; Gerard C Grosveld; James N Ihle
Defective lymphoid development in mice lacking Jak3.
Science (New York, N.Y.) 1995;270(5237):800-2.
1995: Jan M A van Deursen; Maarten Fornerod; B Van Rees; Gerard C Grosveld
Cre-mediated site-specific translocation between nonhomologous mouse chromosomes.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(16):7376-80.
1994: Jan M A van Deursen; Wim Ruitenbeek; Arend Heerschap; PH Jap; Henk ter Laak; Bé Wieringa
Creatine kinase (CK) in skeletal muscle energy metabolism: a study of mouse mutants with graded reduction in muscle CK expression.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(19):9091-5.
1994: Jan M A van Deursen; PH Jap; Arend Heerschap; Henk ter Laak; Wim Ruitenbeek; Bé Wieringa
Effects of the creatine analogue beta-guanidinopropionic acid on skeletal muscles of mice deficient in muscle creatine kinase.
Biochimica et biophysica acta 1994;1185(3):327-35.
1994: Jan M A van Deursen; Bé Wieringa
Approaching the multifaceted nature of energy metabolism: inactivation of the cytosolic creatine kinases via homologous recombination in mouse embryonic stem cells.
Molecular and cellular biochemistry 1994;133-134():263-74.
1993: Jan M A van Deursen; Arend Heerschap; Frank Oerlemans; Wim Ruitenbeek; PH Jap; Henk ter Laak; Bé Wieringa
Skeletal muscles of mice deficient in muscle creatine kinase lack burst activity.
Cell 1993;74(4):621-31.
1992: Jan M A van Deursen; Bé Wieringa
Targeting of the creatine kinase M gene in embryonic stem cells using isogenic and nonisogenic vectors.
Nucleic acids research 1992;20(15):3815-20.
1992: A P Stassen; G J Zaman; Jan M A van Deursen; J G Schoenmakers; RN Konings
Selection and characterization of randomly produced mutants of gene V protein of bacteriophage M13.
European journal of biochemistry / FEBS 1992;204(3):1003-4.
1992: Jan M A van Deursen; Jan Schepens; W Peters; Dies Meijer; Gerard C Grosveld; Wiljan Hendriks; Bé Wieringa
Genetic variability of the murine creatine kinase B gene locus and related pseudogenes in different inbred strains of mice.
Genomics 1992;12(2):340-9.
1991: Jan M A van Deursen; R Lovell-Badge; Frank Oerlemans; Jan Schepens; Bé Wieringa
Modulation of gene activity by consecutive gene targeting of one creatine kinase M allele in mouse embryonic stem cells.
Nucleic acids research 1991;19(10):2637-43.
1990: H C Fries; M B Lamers; Jan M A van Deursen; T Ponnudurai; J H Meuwissen
Biosynthesis of the 25-kDa protein in the macrogametes/zygotes of Plasmodium falciparum.
Experimental parasitology 1990;71(2):229-35.
1986: A N Vermeulen; Jan M A van Deursen; R H Brakenhoff; T H Lensen; T Ponnudurai; J H Meuwissen
Characterization of Plasmodium falciparum sexual stage antigens and their biosynthesis in synchronised gametocyte cultures.
Molecular and biochemical parasitology 1986;20(2):155-63.