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Sander van Deventer

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Florie Borel; Ruiqi Han; Peter L M Jansen; Pavlina Konstantinova; Harald Petry; Sander J H van Deventer; Allerdien Visser
Adenosine triphosphate-binding cassette transporter genes up-regulation in untreated hepatocellular carcinoma is mediated by cellular microRNAs.
Inge L Huibregtse; Martien L Kapsenberg; Maikel Peppelenbosch; Maria A Sartori da Silva; Sander J H van Deventer; Sebatian A Zaat; Henri Braat
Genetically Modified Lactococcus lactis for Delivery of Human Interleukin-10 to Dendritic Cells.
Inge L Huibregtse; Eric V Marietta; Shadi Rashtak; Frits Koning; Pieter Rottiers; Chella S David; Sander J H van Deventer; Joseph A Murray
Induction of antigen-specific tolerance by oral administration of Lactococcus lactis delivered immunodominant DQ8-restricted gliadin peptide in sensitized nonobese diabetic Abo Dq8 transgenic mice.

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2012: Florie Borel; Ruiqi Han; Peter L M Jansen; Pavlina Konstantinova; Harald Petry; Sander J H van Deventer; Allerdien Visser
Adenosine triphosphate-binding cassette transporter genes up-regulation in untreated hepatocellular carcinoma is mediated by cellular microRNAs.
Hepatology (Baltimore, Md.) 2012;55(3):821-32.
2012: Inge L Huibregtse; Martien L Kapsenberg; Maikel Peppelenbosch; Maria A Sartori da Silva; Sander J H van Deventer; Sebatian A Zaat; Henri Braat
Genetically Modified Lactococcus lactis for Delivery of Human Interleukin-10 to Dendritic Cells.
Gastroenterology research and practice 2012;2012():639291.
2009: Inge L Huibregtse; Eric V Marietta; Shadi Rashtak; Frits Koning; Pieter Rottiers; Chella S David; Sander J H van Deventer; Joseph A Murray
Induction of antigen-specific tolerance by oral administration of Lactococcus lactis delivered immunodominant DQ8-restricted gliadin peptide in sensitized nonobese diabetic Abo Dq8 transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(4):2390-6.
2007: Johannes Levels; Dasja Pajkrt; Marcus Schultz; Frans J Hoek; Arie Van Tol; Joost C M Meijers; Sander J H van Deventer
Alterations in lipoprotein homeostasis during human experimental endotoxemia and clinical sepsis.
Biochimica et biophysica acta 2007;1771(12):1429-38.
2007: Sylvia A Bleuming; Xi C He; Liudmila L Kodach; James C H Hardwick; Frieda A Koopman; Fiebo J W Ten Kate; Sander J H van Deventer; Daan W Hommes; Maikel Peppelenbosch; G Johan A Offerhaus; Linheng Li; Gijs R van den Brink
Bone morphogenetic protein signaling suppresses tumorigenesis at gastric epithelial transition zones in mice.
Cancer research 2007;67(17):8149-55.
2007: Huub Gelderblom; Laurens E J Nijhuis; Esther C de Jong; Anje A Te Velde; Dasja Pajkrt; Henk W Reesink; Marcel G H M Beld; Sander J H van Deventer; Peter L M Jansen
Monocyte-derived dendritic cells from chronic HCV patients are not infected but show an immature phenotype and aberrant cytokine profile.
Liver international : official journal of the International Association for the Study of the Liver 2007;27(7):944-53.
2007: Inge L Huibregtse; Veerle Snoeck; An De Creus; Henri Braat; Esther C de Jong; Sander J H van Deventer; Pieter Rottiers
Induction of ovalbumin-specific tolerance by oral administration of Lactococcus lactis secreting ovalbumin.
Gastroenterology 2007;133(2):517-28.
2007: Lissy de Ridder; Marc Benninga; Jan A J M Taminiau; Daan W Hommes; Sander J H van Deventer
Infliximab use in children and adolescents with inflammatory bowel disease.
Journal of pediatric gastroenterology and nutrition 2007;45(1):3-14.
2007: Francesca Milano; Jantine van Baal; Agnieszka M Rygiel; Jacques J G H M Bergman; Sander J H van Deventer; Martien L Kapsenberg; Maikel Peppelenbosch; Kausilia K Krishnadath
An improved protocol for generation of immuno-potent dendritic cells through direct electroporation of CD14+ monocytes.
Journal of immunological methods 2007;321(1-2):94-106.
2007: Jan M H Van Den Brande; Tamara C Koehler; Zuzana Zelinkova; Roelof J Bennink; Anje A Te Velde; Fibo J W ten Cate; Sander J H van Deventer; Maikel Peppelenbosch; Daan W Hommes
Prediction of antitumour necrosis factor clinical efficacy by real-time visualisation of apoptosis in patients with Crohn's disease.
Gut 2007;56(4):509-17.
2007: Inge L Huibregtse; Anja U van Lent; Sander J H van Deventer
Immunopathogenesis of IBD: insufficient suppressor function in the gut?
Gut 2007;56(4):584-92.
2007: Evelien Dekker; F J van den Broek; Johannes B Reitsma; James C H Hardwick; G Johan A Offerhaus; Sander J H van Deventer; Daan W Hommes; Paul Fockens
Narrow-band imaging compared with conventional colonoscopy for the detection of dysplasia in patients with longstanding ulcerative colitis.
Endoscopy 2007;39(3):216-21.
2007: Anje A Te Velde; Floor de Kort; Ellen Sterrenburg; Inge Pronk; Fiebo J W Ten Kate; Daan W Hommes; Sander J H van Deventer
Comparative analysis of colonic gene expression of three experimental colitis models mimicking inflammatory bowel disease.
Inflammatory bowel diseases 2007;13(3):325-30.
2007: Henri Braat; Peter McGuirk; Fiebo J W Ten Kate; Inge L Huibregtse; Padraic J Dunne; Daan W Hommes; Sander J H van Deventer; Kingston H G Mills
Prevention of experimental colitis by parenteral administration of a pathogen-derived immunomodulatory molecule.
Gut 2007;56(3):351-7.
2006: Paulus H S Kwakman; Anje A Te Velde; Christina M.J.E, Vandenbroucke-Grauls; Sander J H van Deventer; Sebastian A J Zaat
Treatment and prevention of Staphylococcus epidermidis experimental biomaterial-associated infection by bactericidal peptide 2.
Antimicrobial agents and chemotherapy 2006;50(12):3977-83.
2006: Mark Löwenberg; Auke Verhaar; Joyce Bilderbeek; Frank Buttgereit; Maikel Peppelenbosch; Sander J H van Deventer; Jan van Marle; Daan W Hommes
Glucocorticoids cause rapid dissociation of a T-cell-receptor-associated protein complex containing LCK and FYN.
EMBO reports 2006;7(10):1023-9.
2006: Karin van Gemert-Horsthuis; Jasper Florie; Daniel W Hommes; Cristina Lavini; Johannes B Reitsma; Sander J H van Deventer; Jaap Stoker
Feasibility of evaluating Crohn's disease activity at 3.0 Tesla.
Journal of magnetic resonance imaging : JMRI 2006;24(2):340-8.
2006: Walter Reinisch; Daan W Hommes; G Van Assche; J-F Colombel; J-P Gendre; B Oldenburg; Alexander Teml; K Geboes; H Ding; L Zhang; M Tang; M Cheng; Sander J H van Deventer; P Rutgeerts; T Pearce
A dose escalating, placebo controlled, double blind, single dose and multidose, safety and tolerability study of fontolizumab, a humanised anti-interferon gamma antibody, in patients with moderate to severe Crohn's disease.
Gut 2006;55(8):1138-44.
2006: Mark Löwenberg; Jurriaan Tuynman; Meike Scheffer; Auke Verhaar; Louis Vermeulen; Sander J H van Deventer; Daan W Hommes; Maikel Peppelenbosch
Kinome analysis reveals nongenomic glucocorticoid receptor-dependent inhibition of insulin signaling.
Endocrinology 2006;147(7):3555-62.
2006: Henri Braat; Pieter Rottiers; Daan W Hommes; Nathalie Huyghebaert; Erik Remaut; Jean Paul Remon; Sander J H van Deventer; Sabine Neirynck; Maikel Peppelenbosch; Lothar Steidler
A phase I trial with transgenic bacteria expressing interleukin-10 in Crohn's disease.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2006;4(6):754-9.
2006: Sander J H van Deventer; Mark K Wedel; Brenda F Baker; S Xia; Emil Chuang; Philip B Miner
A phase II dose ranging, double-blind, placebo-controlled study of alicaforsen enema in subjects with acute exacerbation of mild to moderate left-sided ulcerative colitis.
Alimentary pharmacology & therapeutics 2006;23(10):1415-25.
2006: Pieter C F Stokkers; Maartje Deley; Mirjam Van Der Spek; Hein J Verberne; Sander J H van Deventer; Daan W Hommes
Intravenous pamidronate in combination with calcium and vitamin D: highly effective in the treatment of low bone mineral density in inflammatory bowel disease.
Scandinavian journal of gastroenterology 2006;41(2):200-4.
2006: Jeroen C van Rijn; Johannes B Reitsma; Jaap Stoker; Patrick Bossuyt; Sander J H van Deventer; Evelien Dekker
Polyp miss rate determined by tandem colonoscopy: a systematic review.
The American journal of gastroenterology 2006;101(2):343-50.
2006: Luc J J Derijks; L P L Gilissen; Leopold G J B Engels; Laurens P Bos; Paul J Bus; J J H M Lohman; Sander J H van Deventer; Daan W Hommes; Piet M Hooymans
Pharmacokinetics of 6-thioguanine in patients with inflammatory bowel disease.
Therapeutic drug monitoring 2006;28(1):45-50.
2006: Zuzana Zelinkova; Luc J J Derijks; Pieter C F Stokkers; Esther W M Vogels; Antoine H C van Kampen; Wouter L Curvers; Danny Cohn; Sander J H van Deventer; Daan W Hommes
Inosine triphosphate pyrophosphatase and thiopurine s-methyltransferase genotypes relationship to azathioprine-induced myelosuppression.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2006;4(1):44-9.
2005: Jasper Florie; Karin Horsthuis; Daniel W Hommes; C Yung Nio; Johannes B Reitsma; Sander J H van Deventer; Jaap Stoker
Magnetic resonance imaging compared with ileocolonoscopy in evaluating disease severity in Crohn's disease.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2005;3(12):1221-8.
2005: William J Sandborn; Jean-Frédéric Colombel; Roberts Enns; Brian G Feagan; Stephen B Hanauer; Ian Craig Lawrance; Remo Panaccione; Martin Sanders; Stefan Schreiber; Stephan R Targan; Sander J H van Deventer; Ronald Goldblum; Darrin Despain; Gary S Hogge; Paul Rutgeerts
Natalizumab induction and maintenance therapy for Crohn's disease.
The New England journal of medicine 2005;353(18):1912-25.
2005: L E M Willemsen; J P Hoetjes; Sander J H van Deventer; E A F Van Tol
Abrogation of IFN-gamma mediated epithelial barrier disruption by serine protease inhibition.
Clinical and experimental immunology 2005;142(2):275-84.
2005: Jantine van Baal; Francesca Milano; Agnieszka M Rygiel; Jacques J G H M Bergman; Wilda D Rosmolen; Sander J H van Deventer; Kenneth K Wang; Maikel Peppelenbosch; Kausilia K Krishnadath
A comparative analysis by SAGE of gene expression profiles of Barrett's esophagus, normal squamous esophagus, and gastric cardia.
Gastroenterology 2005;129(4):1274-81.
2005: Mark Löwenberg; Jurriaan Tuynman; Joyce Bilderbeek; Timo Gaber; Frank Buttgereit; Sander J H van Deventer; Maikel Peppelenbosch; Daan W Hommes
Rapid immunosuppressive effects of glucocorticoids mediated through Lck and Fyn.
Blood 2005;106(5):1703-10.
2005: Mark Löwenberg; Auke Verhaar; Bernt van den Blink; Fibo ten Kate; Sander J H van Deventer; Maikel Peppelenbosch; Daan W Hommes
Specific inhibition of c-Raf activity by semapimod induces clinical remission in severe Crohn's disease.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(4):2293-300.
2005: Henri Braat; Pieter C F Stokkers; Tijmen Hommes; Danny Cohn; Esther Vogels; Inge Pronk; Arnold Spek; Antoine H C van Kampen; Sander J H van Deventer; Maikel Peppelenbosch; Daan W Hommes
Consequence of functional Nod2 and Tlr4 mutations on gene transcription in Crohn's disease patients.
Journal of molecular medicine (Berlin, Germany) 2005;83(8):601-9.
2005: Mohammed A Kara; Femke P Peters; Fiebo J W Ten Kate; Sander J H van Deventer; Paul Fockens; Jacques J G H M Bergman
Endoscopic video autofluorescence imaging may improve the detection of early neoplasia in patients with Barrett's esophagus.
Gastrointestinal endoscopy 2005;61(6):679-85.
2005: Femke P Peters; Mohammed A Kara; Wilda D Rosmolen; Maurice C G Aalders; Fiebo J W Ten Kate; Bert C Bultje; Kausilia K Krishnadath; Paul Fockens; J J B van Lanschot; Sander J H van Deventer; Jacques J G H M Bergman
Endoscopic treatment of high-grade dysplasia and early stage cancer in Barrett's esophagus.
Gastrointestinal endoscopy 2005;61(4):506-14.
2005: Johannes Levels; J A Marquart; Philip Abraham; Abraham E van den Ende; H O F Molhuizen; Sander J H van Deventer; Joost C M Meijers
Lipopolysaccharide is transferred from high-density to low-density lipoproteins by lipopolysaccharide-binding protein and phospholipid transfer protein.
Infection and immunity 2005;73(4):2321-6.
2005: Roelof J Bennink; Jörg Hamann; Kora de Bruin; Fiebo J W Ten Kate; Sander J H van Deventer; Anje A Te Velde
Dedicated pinhole SPECT of intestinal neutrophil recruitment in a mouse model of dextran sulfate sodium-induced colitis.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2005;46(3):526-31.
2005: M de Visser; M van Ballegooijen; S M Bloemers; Sander J H van Deventer; J B M J Jansen; J Jespersen; Cornelis Kluft; G A Meijer; J Stoker; G A de Valk; M F Verweij; F A Vlems
Report on the Dutch consensus development meeting for implementation and further development of population screening for colorectal cancer based on FOBT.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2005;27(1):17-29.
2004: Henri Braat; Jan M H Van Den Brande; Erik van Tol; Daan W Hommes; Maikel Peppelenbosch; Sander J H van Deventer
Lactobacillus rhamnosus induces peripheral hyporesponsiveness in stimulated CD4+ T cells via modulation of dendritic cell function.
The American journal of clinical nutrition 2004;80(6):1618-25.
2004: Stefan Maartense; Michalda S Dunker; J F M Slors; Miguel A Cuesta; Dirk J Gouma; Sander J H van Deventer; Ad van Bodegraven; Willem A Bemelman
Hand-assisted laparoscopic versus open restorative proctocolectomy with ileal pouch anal anastomosis: a randomized trial.
Annals of surgery 2004;240(6):984-91; discussion 991-2.
2004: Sander J H van Deventer; J A Tami; M K Wedel
A randomised, controlled, double blind, escalating dose study of alicaforsen enema in active ulcerative colitis.
Gut 2004;53(11):1646-51.
2004: Maikel Peppelenbosch; Sander J H van Deventer
T cell apoptosis and inflammatory bowel disease.
Gut 2004;53(11):1556-8.
2004: Bruce Sands; Marion A Blank; Kam Patel; Sander J H van Deventer
Long-term treatment of rectovaginal fistulas in Crohn's disease: response to infliximab in the ACCENT II Study.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2004;2(10):912-20.
2004: Catherine van Montfrans; Roelof J Bennink; Kora de Bruin; Wouter J de Jonge; Hein J Verberne; Fiebo J W Ten Kate; Sander J H van Deventer; Anje A Te Velde
In vivo evaluation of 111In-labeled T-lymphocyte homing in experimental colitis.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(10):1759-65.
2004: Wouter J de Jonge; Frans O The; Dennis van der Coelen; Roelof J Bennink; Pieter H Reitsma; Sander J H van Deventer; Rene M van den Wijngaard; Guy E Boeckxstaens
Mast cell degranulation during abdominal surgery initiates postoperative ileus in mice.
Gastroenterology 2004;127(2):535-45.
2004: Rogier E van Gelder; C Yung Nio; Jasper Florie; Joep F W M Bartelsman; Pleun Snel; Steven W de Jager; Sander J H van Deventer; Johan S Laméris; Patrick Bossuyt; Jaap Stoker
Computed tomographic colonography compared with colonoscopy in patients at increased risk for colorectal cancer.
Gastroenterology 2004;127(1):41-8.
2004: James C H Hardwick; Marije M van Santen; Gijs R van den Brink; Sander J H van Deventer; Maikel Peppelenbosch
DNA array analysis of the effects of aspirin on colon cancer cells: involvement of Rac1.
Carcinogenesis 2004;25(7):1293-8.
2004: Luc J J Derijks; L P L Gilissen; Leopold G J B Engels; Laurens P Bos; Paul J Bus; J J H M Lohman; Wouter L Curvers; Sander J H van Deventer; Daan W Hommes; Piet M Hooymans
Pharmacokinetics of 6-mercaptopurine in patients with inflammatory bowel disease: implications for therapy.
Therapeutic drug monitoring 2004;26(3):311-8.
2004: Tessa ten Hove; F The Olle; Marloes Berkhout; Joost P Bruggeman; Florry A Vyth-Dreese; J F M Slors; Sander J H van Deventer; Anje A Te Velde
Expression of CD45RB functionally distinguishes intestinal T lymphocytes in inflammatory bowel disease.
Journal of leukocyte biology 2004;75(6):1010-5.
2004: Daan W Hommes; Gerben Sterringa; Sander J H van Deventer; G N J Tytgat; Jan F L Weel
The pathogenicity of cytomegalovirus in inflammatory bowel disease: a systematic review and evidence-based recommendations for future research.
Inflammatory bowel diseases 2004;10(3):245-50.
2004: Daan W Hommes; Sander J H van Deventer
Endoscopy in inflammatory bowel diseases.
Gastroenterology 2004;126(6):1561-73.
2004: Gijs R van den Brink; Sylvia A Bleuming; James C H Hardwick; Berber L Schepman; G Johan A Offerhaus; Josbert J Keller; Corinne Nielsen; William Gaffield; Sander J H van Deventer; Drucilla J Roberts; Maikel Peppelenbosch
Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation.
Nature genetics 2004;36(3):277-82.
2004: Henri Braat; Esther C de Jong; Jan M H Van Den Brande; Martien L Kapsenberg; Maikel Peppelenbosch; Eric A F van Tol; Sander J H van Deventer
Dichotomy between Lactobacillus rhamnosus and Klebsiella pneumoniae on dendritic cell phenotype and function.
Journal of molecular medicine (Berlin, Germany) 2004;82(3):197-205.
2004: Catherine van Montfrans; Anje A Te Velde; Sander J H van Deventer; Maria Sol Rodriguez Pena
Gene therapy in the treatment of intestinal inflammation.
International journal of colorectal disease 2004;19(2):79-86.
2004: Bruce Sands; Frank H Anderson; Charles N Bernstein; William Y Chey; Brian G Feagan; Richard N Fedorak; Michael A Kamm; Joshua R Korzenik; Bret A Lashner; Jane E Onken; Daniel Rachmilewitz; Paul Rutgeerts; Gary Wild; Douglas C Wolf; Paul A Marsters; Suzanne Travers; Marion A Blank; Sander J H van Deventer
Infliximab maintenance therapy for fistulizing Crohn's disease.
The New England journal of medicine 2004;350(9):876-85.
2004: G W Erkelens; Sander J H van Deventer
Endoscopic treatment of strictures in Crohn's disease.
Best practice & research. Clinical gastroenterology 2004;18(1):201-7.
2004: Bernt van den Blink; Judith Branger; Sebastiaan Weijer; Abhya Gupta; Sander J H van Deventer; Maikel Peppelenbosch; Tom van der Poll
P38 mitogen activated protein kinase is involved in the downregulation of granulocyte CXC chemokine receptors 1 and 2 during human endotoxemia.
Journal of clinical immunology 2004;24(1):37-41.
2004: Roelof J Bennink; Catherine van Montfrans; Wouter J de Jonge; Kora de Bruin; Sander J H van Deventer; Anje A Te Velde
Imaging of intestinal lymphocyte homing by means of pinhole SPECT in a TNBS colitis mouse model.
Nuclear medicine and biology 2004;31(1):93-101.
2004: James C H Hardwick; Gijs R van den Brink; Sylvia A Bleuming; Isabel Ballester; Jan M H Van Den Brande; Josbert J Keller; G Johan A Offerhaus; Sander J H van Deventer; Maikel Peppelenbosch
Bone morphogenetic protein 2 is expressed by, and acts upon, mature epithelial cells in the colon.
Gastroenterology 2004;126(1):111-21.
2003: Sander H Diks; James C H Hardwick; Remco M Diab; Marije M van Santen; Henri H Versteeg; Sander J H van Deventer; Dick J Richel; Maikel Peppelenbosch
Activation of the canonical beta-catenin pathway by histamine.
The Journal of biological chemistry 2003;278(52):52491-6.
2003: Wouter J de Jonge; Rene M van den Wijngaard; Frans O The; Merel-Linde ter Beek; Roelof J Bennink; G N J Tytgat; Ruud M Buijs; Pieter H Reitsma; Sander J H van Deventer; Guy E Boeckxstaens
Postoperative ileus is maintained by intestinal immune infiltrates that activate inhibitory neural pathways in mice.
Gastroenterology 2003;125(4):1137-47.
2003: L E M Willemsen; M A Koetsier; Sander J H van Deventer; E A F Van Tol
Short chain fatty acids stimulate epithelial mucin 2 expression through differential effects on prostaglandin E(1) and E(2) production by intestinal myofibroblasts.
Gut 2003;52(10):1442-7.
2003: Michalda S Dunker; Tessa ten Hove; Willem A Bemelman; J F M Slors; Dirk J Gouma; Sander J H van Deventer
Interleukin-6, C-reactive protein, and expression of human leukocyte antigen-DR on peripheral blood mononuclear cells in patients after laparoscopic vs. conventional bowel resection: a randomized study.
Diseases of the colon and rectum 2003;46(9):1238-44.
2003: Daan W Hommes; Sander J H van Deventer
Targeting tumor necrosis factor-alpha in inflammatory bowel disease: why, how, and when?
Current opinion in gastroenterology 2003;19(4):350-7.
2003: Dariusz P Olszyna; Annelies Verbon; John P Pribble; Terence Turner; Tim Axtelle; Sander J H van Deventer; Tom van der Poll
Effect of IC14, an anti-CD14 antibody, on plasma and cell-associated chemokines during human endotoxemia.
European cytokine network 2003;14(3):158-62.
2003: Paul Rutgeerts; Sander J H van Deventer; S Schreiber
Review article: the expanding role of biological agents in the treatment of inflammatory bowel disease - focus on selective adhesion molecule inhibition.
Alimentary pharmacology & therapeutics 2003;17(12):1435-50.
2003: Jan M H Van Den Brande; Henri Braat; Gijs R van den Brink; Henri H Versteeg; Christiaan A Bauer; Inge Hoedemaeker; Catherine van Montfrans; Daan W Hommes; Maikel Peppelenbosch; Sander J H van Deventer
Infliximab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn's disease.
Gastroenterology 2003;124(7):1774-85.
2003: Johannes Levels; Luciënne C J M Lemaire; Abraham E van den Ende; Sander J H van Deventer; J J B van Lanschot
Lipid composition and lipopolysaccharide binding capacity of lipoproteins in plasma and lymph of patients with systemic inflammatory response syndrome and multiple organ failure.
Critical care medicine 2003;31(6):1647-53.
2003: Anne-Marie van Berkel; Marco J Bruno; Jacques J G H M Bergman; Sander J H van Deventer; G N J Tytgat; Kees Huibregtse
A prospective randomized study of hydrophilic polymer-coated polyurethane versus polyethylene stents in distal malignant biliary obstruction.
Endoscopy 2003;35(6):478-82.
2003: Johannes Levels; Philip Abraham; Erik P van Barreveld; Joost C M Meijers; Sander J H van Deventer
Distribution and kinetics of lipoprotein-bound lipoteichoic acid.
Infection and immunity 2003;71(6):3280-4.
2003: Judith Branger; Bernt van den Blink; Sebastiaan Weijer; Abhya Gupta; Sander J H van Deventer; C Erik Hack; Maikel Peppelenbosch; Tom van der Poll
Inhibition of coagulation, fibrinolysis, and endothelial cell activation by a p38 mitogen-activated protein kinase inhibitor during human endotoxemia.
Blood 2003;101(11):4446-8.
2003: Henri H Versteeg; H L Bresser; C Arnold Spek; Dick J Richel; Sander J H van Deventer; Maikel Peppelenbosch
Regulation of the p21Ras-MAP kinase pathway by factor VIIa.
Journal of thrombosis and haemostasis : JTH 2003;1(5):1012-8.
2003: Daan W Hommes; Sander J H van Deventer
Infliximab therapy in Crohn's disease: safety issues.
The Netherlands journal of medicine 2003;61(4):100-4.
2003: Martijn R van de Scheur; R I F van der Waal; Isaäc van der Waal; Tom J Stoof; Sander J H van Deventer
Ano-genital granulomatosis: the counterpart of oro-facial granulomatosis.
Journal of the European Academy of Dermatology and Venereology : JEADV 2003;17(2):184-9.
2003: Sander J H van Deventer
New biological therapies in inflammatory bowel disease.
Best practice & research. Clinical gastroenterology 2003;17(1):119-30.
2003: Petra J G Zwijnenburg; Machteld M J Polfliet; Sandrine Florquin; Timo K van den Berg; Christine D Dijkstra; Sander J H van Deventer; John J Roord; Tom van der Poll; A Marceline van Furth
CXC-chemokines KC and macrophage inflammatory protein-2 (MIP-2) synergistically induce leukocyte recruitment to the central nervous system in rats.
Immunology letters 2003;85(1):1-4.
2003: Anje A Te Velde; Yvette van Kooyk; Henri Braat; Daan W Hommes; Trees A M Dellemijn; J F M Slors; Sander J H van Deventer; Florry A Vyth-Dreese
Increased expression of DC-SIGN+IL-12+IL-18+ and CD83+IL-12-IL-18- dendritic cell populations in the colonic mucosa of patients with Crohn's disease.
European journal of immunology 2003;33(1):143-51.
2003: Annelies Verbon; Joost C M Meijers; C Arnold Spek; C Erik Hack; John P Pribble; Terence Turner; Pascale E P Dekkers; Tim Axtelle; Marcel Levi; Sander J H van Deventer; Pieter H Reitsma; Tom van der Poll
Effects of IC14, an anti-CD14 antibody, on coagulation and fibrinolysis during low-grade endotoxemia in humans.
The Journal of infectious diseases 2003;187(1):55-61.
2003: Daan W Hommes; Maikel Peppelenbosch; Sander J H van Deventer
Mitogen activated protein (MAP) kinase signal transduction pathways and novel anti-inflammatory targets.
Gut 2003;52(1):144-51.
2002: Sander J H van Deventer
Taming the mucosal immune response in Crohn's disease.
Best practice & research. Clinical gastroenterology 2002;16(6):1035-43.
2002: J Lindsay; Catherine van Montfrans; Fionula Brennan; Sander J H van Deventer; P Drillenburg; Humphrey Hodgson; Anje A Te Velde; M Sol Rodriguez Pena
IL-10 gene therapy prevents TNBS-induced colitis.
Gene therapy 2002;9(24):1715-21.
2002: Catherine van Montfrans; Erik Hooijberg; Maria Sol Rodriguez Pena; Esther C de Jong; Hergen Spits; Anje A Te Velde; Sander J H van Deventer
Generation of regulatory gut-homing human T lymphocytes using ex vivo interleukin 10 gene transfer.
Gastroenterology 2002;123(6):1877-88.
2002: Catherine van Montfrans; Maria Sol Rodriguez Pena; Inge Pronk; Fiebo J W Ten Kate; Anje A Te Velde; Sander J H van Deventer
Prevention of colitis by interleukin 10-transduced T lymphocytes in the SCID mice transfer model.
Gastroenterology 2002;123(6):1865-76.
2002: Bernt van den Blink; Tessa ten Hove; Gijs R van den Brink; Maikel Peppelenbosch; Sander J H van Deventer
From extracellular to intracellular targets, inhibiting MAP kinases in treatment of Crohn's disease.
Annals of the New York Academy of Sciences 2002;973():349-58.
2002: Jan M H Van Den Brande; Maikel Peppelenbosch; Sander J H van Deventer
Treating Crohn's disease by inducing T lymphocyte apoptosis.
Annals of the New York Academy of Sciences 2002;973():166-80.
2002: Wouter J de Jonge; Karin L Kwikkers; Anje A Te Velde; Sander J H van Deventer; Martijn A Nolte; Reina E Mebius; Jan M Ruijter; Marinus C Lamers; Wouter H Lamers
Arginine deficiency affects early B cell maturation and lymphoid organ development in transgenic mice.
The Journal of clinical investigation 2002;110(10):1539-48.
2002: Gijs R van den Brink; James C H Hardwick; C Nielsen; C Xu; Fiebo J W Ten Kate; J Glickman; Sander J H van Deventer; Drucilla J Roberts; Maikel Peppelenbosch
Sonic hedgehog expression correlates with fundic gland differentiation in the adult gastrointestinal tract.
Gut 2002;51(5):628-33.
2002: L E M Willemsen; C C H M Schreurs; H Kroes; E J Spillenaar Bilgen; Sander J H van Deventer; E A F Van Tol
A coculture model mimicking the intestinal mucosa reveals a regulatory role for myofibroblasts in immune-mediated barrier disruption.
Digestive diseases and sciences 2002;47(10):2316-24.
2002: Wilbert T Jellema; D Peter Veerman; Robbert J De Winter; Karel H Wesseling; Sander J H van Deventer; C Erik Hack; Johannes Van Lieshout
In vivo interaction of endotoxin and recombinant bactericidal/permeability-increasing protein (rBPI23): hemodynamic effects in a human endotoxemia model.
The Journal of laboratory and clinical medicine 2002;140(4):228-35.
2002: Tessa ten Hove; Paul Drillenburg; Jan Wijnholds; Anje A Te Velde; Sander J H van Deventer
Differential susceptibility of multidrug resistance protein-1 deficient mice to DSS and TNBS-induced colitis.
Digestive diseases and sciences 2002;47(9):2056-63.
2002: Catherine van Montfrans; Maikel Peppelenbosch; Anje A Te Velde; Sander J H van Deventer
Inflammatory signal transduction in Crohn's disease and novel therapeutic approaches.
Biochemical pharmacology 2002;64(5-6):789-95.
2002: Sander J H van Deventer
Anti-tumour necrosis factor therapy in Crohn's disease: where are we now?
Gut 2002;51(3):362-3.
2002: Sander J H van Deventer
The future of inflammatory bowel disease therapy.
Inflammatory bowel diseases 2002;8(4):301-5; discussion 306.
2002: Sander J H van Deventer
A place for TACE.
Gut 2002;51(1):5-6.
2002: B P J van Balkom; Erik J Schoon; Reinhold W Stockbrügger; Frank Wolters; R A van Hogezand; Sander J H van Deventer; B Oldenburg; Hendrik M van Dullemen; M G V M Russel
Effects of anti-tumour necrosis factor-alpha therapy on the quality of life in Crohn's disease.
Alimentary pharmacology & therapeutics 2002;16(6):1101-7.
2002: Sander J H van Deventer
Small therapeutic molecules for the treatment of inflammatory bowel disease.
Gut 2002;50 Suppl 3():III47-53.
2002: Judith Branger; Bernt van den Blink; Sebastiaan Weijer; Jeffrey Madwed; Carina L Bos; Abhya Gupta; Chan-Loi Yong; Stephen H Polmar; Dariusz P Olszyna; C Erik Hack; Sander J H van Deventer; Maikel Peppelenbosch; Tom van der Poll
Anti-inflammatory effects of a p38 mitogen-activated protein kinase inhibitor during human endotoxemia.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):4070-7.
2002: Johanna C Escher; Tom J Stoof; Sander J H van Deventer; A Marcelien van Furth
Successful treatment of metastatic Crohn disease with infliximab.
Journal of pediatric gastroenterology and nutrition 2002;34(4):420-3.
2002: Anne Corbaz; Tessa ten Hove; Suzanne Herren; Pierre Graber; Boris Schwartsburd; Ilana Belzer; Jillian Harrison; Thomas Plitz; Marie H Kosco-Vilbois; Soo-Hyun Kim; Charles A Dinarello; Daniela Novick; Sander J H van Deventer; Yolande Chvatchko
IL-18-binding protein expression by endothelial cells and macrophages is up-regulated during active Crohn's disease.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(7):3608-16.
2002: Tessa ten Hove; Bernt van den Blink; I Pronk; Paul Drillenburg; Maikel Peppelenbosch; Sander J H van Deventer
Dichotomal role of inhibition of p38 MAPK with SB 203580 in experimental colitis.
Gut 2002;50(4):507-12.
2002: Daan W Hommes; Brenda H van de Heisteeg; Mirjam van der Spek; Joep F W M Bartelsman; Sander J H van Deventer
Infliximab treatment for Crohn's disease: one-year experience in a Dutch academic hospital.
Inflammatory bowel diseases 2002;8(2):81-6.
2002: T ten Hove; Catherine van Montfrans; Maikel Peppelenbosch; Sander J H van Deventer
Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease.
Gut 2002;50(2):206-11.
2002: Herbert Tilg; C van Montfrans; A van den Ende; Arthur Kaser; Sander J H van Deventer; S Schreiber; M Gregor; Othmar Ludwiczek; Paul Rutgeerts; Christoph Gasche; J C Koningsberger; L Abreu; I Kuhn; M Cohard; LeBeaut Pierre Alexandre; Paul C Grint; Günter Weiss
Treatment of Crohn's disease with recombinant human interleukin 10 induces the proinflammatory cytokine interferon gamma.
Gut 2002;50(2):191-5.
2002: Luisa Camoglio; Nicole P Juffermans; Maikel Peppelenbosch; Anje A Te Velde; Fibo J ten Kate; Sander J H van Deventer; Manfred Kopf
Contrasting roles of IL-12p40 and IL-12p35 in the development of hapten-induced colitis.
European journal of immunology 2002;32(1):261-9.
2002: Daan W Hommes; Bernt van den Blink; Terry Plasse; Joep F W M Bartelsman; Cuiping Xu; Bret Macpherson; Guido Tytgat; Maikel Peppelenbosch; Sander J H van Deventer
Inhibition of stress-activated MAP kinases induces clinical improvement in moderate to severe Crohn's disease.
Gastroenterology 2002;122(1):7-14.
2002: Gijs R van den Brink; Daniëlle E M van den Boogaardt; Sander J H van Deventer; Maikel Peppelenbosch
Feed a cold, starve a fever?
Clinical and diagnostic laboratory immunology 2002;9(1):182-3.
2002: Anita W Rijneveld; Fanny N Lauw; Marcus Schultz; Sandrine Florquin; Anje A Te Velde; Peter Speelman; Sander J H van Deventer; Tom van der Poll
The role of interferon-gamma in murine pneumococcal pneumonia.
The Journal of infectious diseases 2002;185(1):91-7.
2002: Fanny N Lauw; Judith Branger; Sandrine Florquin; Peter Speelman; Sander J H van Deventer; Shizuo Akira; Tom van der Poll
IL-18 improves the early antimicrobial host response to pneumococcal pneumonia.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):372-8.
2002: Nicole P Juffermans; Jaklien C Leemans; Sandrine Florquin; Annelies Verbon; Arend H J Kolk; Peter Speelman; Sander J H van Deventer; Tom van der Poll
CpG oligodeoxynucleotides enhance host defense during murine tuberculosis.
Infection and immunity 2002;70(1):147-52.
2001: Tessa ten Hove; Anne Corbaz; H Amitai; S Aloni; Ilana Belzer; Pierre Graber; Paul Drillenburg; Sander J H van Deventer; Yolande Chvatchko; Anje A Te Velde
Blockade of endogenous IL-18 ameliorates TNBS-induced colitis by decreasing local TNF-alpha production in mice.
Gastroenterology 2001;121(6):1372-9.
2001: Y H Yuan; Tessa ten Hove; F O The; J F M Slors; Sander J H van Deventer; Anje A Te Velde
Chemokine receptor CXCR3 expression in inflammatory bowel disease.
Inflammatory bowel diseases 2001;7(4):281-6.
2001: Anita W Rijneveld; Sandrine Florquin; Judith Branger; Peter Speelman; Sander J H van Deventer; Tom van der Poll
TNF-alpha compensates for the impaired host defense of IL-1 type I receptor-deficient mice during pneumococcal pneumonia.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(9):5240-6.
2001: Dariusz P Olszyna; Hester Vermeulen; A H Baan; Peter Speelman; Sander J H van Deventer; Dirk J Gouma; Tom van der Poll
Urine interleukin-8 is a marker for urinary tract infection in postoperative patients.
Infection 2001;29(5):274-7.
2001: Marcus Schultz; Anita W Rijneveld; Sandrine Florquin; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Impairment of host defence by exotoxin A in Pseudomonas aeruginosa pneumonia in mice.
Journal of medical microbiology 2001;50(9):822-7.
2001: Fanny N Lauw; Sandrine Florquin; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Role of endogenous interleukin-12 in immune response to staphylococcal enterotoxin B in mice.
Infection and immunity 2001;69(9):5949-52.
2001: Gijs R van den Brink; James C H Hardwick; G N J Tytgat; M A Brink; Fiebo J W Ten Kate; Sander J H van Deventer; Maikel Peppelenbosch
Sonic hedgehog regulates gastric gland morphogenesis in man and mouse.
Gastroenterology 2001;121(2):317-28.
2001: Dariusz P Olszyna; Dasja Pajkrt; Sander J H van Deventer; Tom van der Poll
Effect of interleukin 10 on the release of the CXC chemokines growth related oncogene GRO-alpha and epithelial cell-derived neutrophil activating peptide (ENA)-78 during human endotoxemia.
Immunology letters 2001;78(1):41-4.
2001: Nicole P Juffermans; Pascale E P Dekkers; Annelies Verbon; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Concurrent upregulation of urokinase plasminogen activator receptor and CD11b during tuberculosis and experimental endotoxemia.
Infection and immunity 2001;69(8):5182-5.
2001: Dariusz P Olszyna; Sandrine Florquin; Miguel E Sewnath; Judith Branger; Peter Speelman; Sander J H van Deventer; R M Strieter; Tom van der Poll
CXC chemokine receptor 2 contributes to host defense in murine urinary tract infection.
The Journal of infectious diseases 2001;184(3):301-7.
2001: James C H Hardwick; Gijs R van den Brink; G Johan A Offerhaus; Sander J H van Deventer; Maikel Peppelenbosch
Leptin is a growth factor for colonic epithelial cells.
Gastroenterology 2001;121(1):79-90.
2001: Jean-Frédéric Colombel; Paul Rutgeerts; Helmut A Malchow; M Jacyna; O H Nielsen; Jørgen Rask-Madsen; Sander J H van Deventer; A Ferguson; Pierre Desreumaux; A Forbes; K Geboes; L Melani; M Cohard
Interleukin 10 (Tenovil) in the prevention of postoperative recurrence of Crohn's disease.
Gut 2001;49(1):42-6.
2001: Evert de Jonge; Pascale E P Dekkers; A A Creasey; C Erik Hack; S K Paulson; A Karim; Jozef Kesecioglu; Marcel Levi; Sander J H van Deventer; Tom van der Poll
Tissue factor pathway inhibitor does not influence inflammatory pathways during human endotoxemia.
The Journal of infectious diseases 2001;183(12):1815-8.
2001: Nicole P Juffermans; Annelies Verbon; Marcus Schultz; C Erik Hack; Sander J H van Deventer; Peter Speelman; Tom van der Poll
Thalidomide inhibits granulocyte responses in healthy humans after ex vivo stimulation with bacterial antigens.
Antimicrobial agents and chemotherapy 2001;45(5):1547-9.
2001: Johannes Levels; Philip Abraham; Abraham E van den Ende; Sander J H van Deventer
Distribution and kinetics of lipoprotein-bound endotoxin.
Infection and immunity 2001;69(5):2821-8.
2001: Jaklien C Leemans; Nicole P Juffermans; Sandrine Florquin; Nico van Rooijen; Margriet J Vervoordeldonk; Annelies Verbon; Sander J H van Deventer; Tom van der Poll
Depletion of alveolar macrophages exerts protective effects in pulmonary tuberculosis in mice.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(7):4604-11.
2001: Dariusz P Olszyna; Evert de Jonge; Pascale E P Dekkers; Sander J H van Deventer; Tom van der Poll
Induction of cell-associated chemokines after endotoxin administration to healthy humans.
Infection and immunity 2001;69(4):2736-8.
2001: Petra J G Zwijnenburg; Tom van der Poll; Sandrine Florquin; Sander J H van Deventer; John J Roord; A Marceline van Furth
Experimental pneumococcal meningitis in mice: a model of intranasal infection.
The Journal of infectious diseases 2001;183(7):1143-6.
2001: Marcus Schultz; J Wijnholds; Maikel Peppelenbosch; Margriet J Vervoordeldonk; Peter Speelman; Sander J H van Deventer; P Borst; Tom van der Poll
Mice lacking the multidrug resistance protein 1 are resistant to Streptococcus pneumoniae-induced pneumonia.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(6):4059-64.
2001: Marcus Schultz; Anita W Rijneveld; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Endogenous interferon-gamma impairs bacterial clearance from lungs during Pseudomonas aeruginosa pneumonia.
European cytokine network 2001;12(1):39-44.
2001: N Kimmings; Miguel E Sewnath; W M Mairuhu; A P Van Zanten; Erik A J Rauws; Sander J H van Deventer; Dirk J Gouma
The abnormal lipid spectrum in malignant obstructive jaundice in relation to endotoxin sensitivity and the result of preoperative biliary drainage.
Surgery 2001;129(3):282-91.
2001: Annelies Verbon; Pascale E P Dekkers; Tessa ten Hove; C Erik Hack; John P Pribble; Terence Turner; Sonia Souza; Tim Axtelle; Frans J Hoek; Sander J H van Deventer; Tom van der Poll
IC14, an anti-CD14 antibody, inhibits endotoxin-mediated symptoms and inflammatory responses in humans.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(5):3599-605.
2001: James C H Hardwick; Gijs R van den Brink; G Johan A Offerhaus; Sander J H van Deventer; Maikel Peppelenbosch
NF-kappaB, p38 MAPK and JNK are highly expressed and active in the stroma of human colonic adenomatous polyps.
Oncogene 2001;20(7):819-27.
2001: Nicole P Juffermans; Peter Speelman; Annelies Verbon; J Veenstra; C Jie; Sander J H van Deventer; Tom van der Poll
Patients with active tuberculosis have increased expression of HIV coreceptors CXCR4 and CCR5 on CD4(+) T cells.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2001;32(4):650-2.
2001: Sander H Diks; Sander J H van Deventer; Maikel Peppelenbosch
Lipopolysaccharide recognition, internalisation, signalling and other cellular effects.
Journal of endotoxin research 2001;7(5):335-48.
2001: Bernt van den Blink; Nicole P Juffermans; Tessa ten Hove; Marcus Schultz; Sander J H van Deventer; Tom van der Poll; Maikel Peppelenbosch
p38 mitogen-activated protein kinase inhibition increases cytokine release by macrophages in vitro and during infection in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(1):582-7.
2000: S Schreiber; Richard N Fedorak; O H Nielsen; Gary Wild; C N Williams; S Nikolaus; M Jacyna; B A Lashner; A Gangl; Paul Rutgeerts; Kim L Isaacs; Sander J H van Deventer; J C Koningsberger; M Cohard; LeBeaut Pierre Alexandre; Stephen B Hanauer
Safety and efficacy of recombinant human interleukin 10 in chronic active Crohn's disease. Crohn's Disease IL-10 Cooperative Study Group.
Gastroenterology 2000;119(6):1461-72.
2000: Miguel E Sewnath; Johannes Levels; Ronald P J Oude Elferink; Cornelis J F Van Noorden; Fiebo J W Ten Kate; Sander J H van Deventer; Dirk J Gouma
Endotoxin-induced mortality in bile duct-ligated rats after administration of reconstituted high-density lipoprotein.
Hepatology (Baltimore, Md.) 2000;32(6):1289-99.
2000: Dariusz P Olszyna; S M Opal; Jan M Prins; DL Horn; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Chemotactic activity of CXC chemokines interleukin-8, growth-related oncogene-alpha, and epithelial cell-derived neutrophil-activating protein-78 in urine of patients with urosepsis.
The Journal of infectious diseases 2000;182(6):1731-7.
2000: Marcus Schultz; Peter Speelman; Sebastian A J Zaat; C E Hack; Sander J H van Deventer; Tom van der Poll
The effect of pseudomonas exotoxin A on cytokine production in whole blood exposed to Pseudomonas aeruginosa.
FEMS immunology and medical microbiology 2000;29(3):227-32.
2000: Nicole P Juffermans; William A Paxton; Pascale E P Dekkers; Annelies Verbon; Evert de Jonge; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Up-regulation of HIV coreceptors CXCR4 and CCR5 on CD4(+) T cells during human endotoxemia and after stimulation with (myco)bacterial antigens: the role of cytokines.
Blood 2000;96(8):2649-54.
2000: Marcus Schultz; Dariusz P Olszyna; Evert de Jonge; Annelies Verbon; Sander J H van Deventer; Tom van der Poll
Reduced ex vivo chemokine production by polymorphonuclear cells after in vivo exposure of normal humans to endotoxin.
The Journal of infectious diseases 2000;182(4):1264-7.
2000: Henri H Versteeg; Evert H J Nijhuis; Gijs R van den Brink; M Evertzen; Gwenda Pynaert; Sander J H van Deventer; Paul J Coffer; Maikel Peppelenbosch
A new phosphospecific cell-based ELISA for p42/p44 mitogen-activated protein kinase (MAPK), p38 MAPK, protein kinase B and cAMP-response-element-binding protein.
The Biochemical journal 2000;350 Pt 3():717-22.
2000: Henri H Versteeg; I Hoedemaeker; Sander H Diks; Jord Stam; M Spaargaren; Paul M P van Bergen en Henegouwen; Sander J H van Deventer; Maikel Peppelenbosch
Factor VIIa/tissue factor-induced signaling via activation of Src-like kinases, phosphatidylinositol 3-kinase, and Rac.
The Journal of biological chemistry 2000;275(37):28750-6.
2000: Gijs R van den Brink; T O'Toole; James C H Hardwick; Daniëlle E M van den Boogaardt; Henri H Versteeg; Sander J H van Deventer; Maikel Peppelenbosch
Leptin signaling in human peripheral blood mononuclear cells, activation of p38 and p42/44 mitogen-activated protein (MAP) kinase and p70 S6 kinase.
Molecular cell biology research communications : MCBRC 2000;4(3):144-50.
2000: A N Kimmings; Sander J H van Deventer; Kees Huibregtse; Dirk J Gouma
Systemic inflammatory response in acute cholangitis and after subsequent treatment.
The European journal of surgery = Acta chirurgica 2000;166(9):700-5.
2000: Annelies Verbon; Nicole P Juffermans; Peter Speelman; Sander J H van Deventer; I J ten Berge; Henk-Jan Guchelaar; Tom van der Poll
A single oral dose of thalidomide enhances the capacity of lymphocytes to secrete gamma interferon in healthy humans.
Antimicrobial agents and chemotherapy 2000;44(9):2286-90.
2000: Nicole P Juffermans; Sandrine Florquin; Luisa Camoglio; Annelies Verbon; Arend H J Kolk; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Interleukin-1 signaling is essential for host defense during murine pulmonary tuberculosis.
The Journal of infectious diseases 2000;182(3):902-8.
2000: Nicole P Juffermans; Pascale E P Dekkers; Maikel Peppelenbosch; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Expression of the chemokine receptors CXCR1 and CXCR2 on granulocytes in human endotoxemia and tuberculosis: involvement of the p38 mitogen-activated protein kinase pathway.
The Journal of infectious diseases 2000;182(3):888-94.
2000: Fanny N Lauw; Dasja Pajkrt; C Erik Hack; M Kurimoto; Sander J H van Deventer; Tom van der Poll
Proinflammatory effects of IL-10 during human endotoxemia.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(5):2783-9.
2000: Maikel Peppelenbosch; M Desmedt; Gwenda Pynaert; Sander J H van Deventer; Johan Grooten
Macrophages present pinocytosed exogenous antigen via MHC class I whereas antigen ingested by receptor-mediated endocytosis is presented via MHC class II.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(4):1984-91.
2000: Nicole P Juffermans; Annelies Verbon; John Belisle; Preston J Hill; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Mycobacterial lipoarabinomannan induces an inflammatory response in the mouse lung. A role for interleukin-1.
American journal of respiratory and critical care medicine 2000;162(2 Pt 1):486-9.
2000: Marcus Schultz; Peter Speelman; C Erik Hack; Wim A Buurman; Sander J H van Deventer; Tom van der Poll
Intravenous infusion of erythromycin inhibits CXC chemokine production, but augments neutrophil degranulation in whole blood stimulated with Streptococcus pneumoniae.
The Journal of antimicrobial chemotherapy 2000;46(2):235-40.
2000: Rendrik F Franco; Evert de Jonge; Pascale E P Dekkers; Janneke J Timmerman; C Arnold Spek; Sander J H van Deventer; P van Deursen; L van Kerkhoff; B van Gemen; Hugo ten Cate; Tom van der Poll; Pieter H Reitsma
The in vivo kinetics of tissue factor messenger RNA expression during human endotoxemia: relationship with activation of coagulation.
Blood 2000;96(2):554-9.
2000: Fanny N Lauw; AJ Simpson; C Erik Hack; Jan M Prins; Angela M Wolbink; Sander J H van Deventer; W Chaowagul; Nicholas J White; Tom van der Poll
Soluble granzymes are released during human endotoxemia and in patients with severe infection due to gram-negative bacteria.
The Journal of infectious diseases 2000;182(1):206-13.
2000: Fanny N Lauw; AJ Simpson; Jan M Prins; Sander J H van Deventer; W Chaowagul; Nicholas J White; Tom van der Poll
The CXC chemokines gamma interferon (IFN-gamma)-inducible protein 10 and monokine induced by IFN-gamma are released during severe melioidosis.
Infection and immunity 2000;68(7):3888-93.
2000: Pascale E P Dekkers; Nicole P Juffermans; T t Hove; Evert de Jonge; Sander J H van Deventer; Tom van der Poll
Granulocyte colony-stimulating factor receptors on granulocytes are down-regulated after endotoxin administration to healthy humans.
The Journal of infectious diseases 2000;181(6):2067-70.
2000: Pieter C F Stokkers; K Huibregtse; AC Leegwater; Pieter H Reitsma; G N J Tytgat; Sander J H van Deventer
Analysis of a positional candidate gene for inflammatory bowel disease: NRAMP2.
Inflammatory bowel diseases 2000;6(2):92-8.
2000: Nicole P Juffermans; Annelies Verbon; Dariusz P Olszyna; Sander J H van Deventer; Peter Speelman; Tom van der Poll
Thalidomide suppresses Up-regulation of human immunodeficiency virus coreceptors CXCR4 and CCR5 on CD4+ T cells in humans.
The Journal of infectious diseases 2000;181(5):1813-6.
2000: Luisa Camoglio; Anje A Te Velde; A de Boer; F J ten Kate; M Kopf; Sander J H van Deventer
Hapten-induced colitis associated with maintained Th1 and inflammatory responses in IFN-gamma receptor-deficient mice.
European journal of immunology 2000;30(5):1486-95.
2000: Pascale E P Dekkers; Tessa ten Hove; Fanny N Lauw; HR Koene; P Lumley; Sander J H van Deventer; Tom van der Poll
The metalloproteinase inhibitor GI5402 inhibits endotoxin-induced soluble CD27 and CD16 release in healthy humans.
Infection and immunity 2000;68(5):3036-9.
2000: A N Kimmings; Sander J H van Deventer; Huug Obertop; Erik A J Rauws; Kees Huibregtse; Dirk J Gouma
Endotoxin, cytokines, and endotoxin binding proteins in obstructive jaundice and after preoperative biliary drainage.
Gut 2000;46(5):725-31.
2000: Benien E van Aken; Martin den Heijer; G M Bos; Sander J H van Deventer; Pieter H Reitsma
Recurrent venous thrombosis and markers of inflammation.
Thrombosis and haemostasis 2000;83(4):536-9.
2000: Pascale E P Dekkers; Tessa ten Hove; Anje A Te Velde; Sander J H van Deventer; Tom van der Poll
Upregulation of monocyte urokinase plasminogen activator receptor during human endotoxemia.
Infection and immunity 2000;68(4):2156-60.
2000: Benien E van Aken; J Jansen; Sander J H van Deventer; Pieter H Reitsma
Elevated levels of homocysteine increase IL-6 production in monocytic Mono Mac 6 cells.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2000;11(2):159-64.
2000: Pascale E P Dekkers; Nicole P Juffermans; Tessa ten Hove; Evert de Jonge; Sander J H van Deventer; Tom van der Poll
Endotoxin down-regulates monocyte and granulocyte interleukin-6 receptors without influencing gp130 expression in humans.
The Journal of infectious diseases 2000;181(3):1055-61.
2000: Fanny N Lauw; Tessa ten Hove; Pascale E P Dekkers; Evert de Jonge; Sander J H van Deventer; Tom van der Poll
Reduced Th1, but not Th2, cytokine production by lymphocytes after in vivo exposure of healthy subjects to endotoxin.
Infection and immunity 2000;68(3):1014-8.
2000: Evert de Jonge; Pascale E P Dekkers; A A Creasey; C Erik Hack; S K Paulson; A Karim; Jozef Kesecioglu; Marcel Levi; Sander J H van Deventer; Tom van der Poll
Tissue factor pathway inhibitor dose-dependently inhibits coagulation activation without influencing the fibrinolytic and cytokine response during human endotoxemia.
Blood 2000;95(4):1124-9.
2000: Dariusz P Olszyna; Dasja Pajkrt; Fanny N Lauw; Sander J H van Deventer; Tom van der Poll
Interleukin 10 inhibits the release of CC chemokines during human endotoxemia.
The Journal of infectious diseases 2000;181(2):613-20.
2000: Henri H Versteeg; M W Evertzen; Sander J H van Deventer; Maikel Peppelenbosch
The role of phosphatidylinositide-3-kinase in basal mitogen-activated protein kinase activity and cell survival.
FEBS letters 2000;465(1):69-73.
2000: Sander J H van Deventer
Immunotherapy of Crohn's disease.
Scandinavian journal of immunology 2000;51(1):18-22.
1999: Fanny N Lauw; AJ Simpson; Jan M Prins; M D Smith; M Kurimoto; Sander J H van Deventer; Peter Speelman; W Chaowagul; Nicholas J White; Tom van der Poll
Elevated plasma concentrations of interferon (IFN)-gamma and the IFN-gamma-inducing cytokines interleukin (IL)-18, IL-12, and IL-15 in severe melioidosis.
The Journal of infectious diseases 1999;180(6):1878-85.
1999: Dariusz P Olszyna; Jan M Prins; Pascale E P Dekkers; Evert de Jonge; Peter Speelman; Sander J H van Deventer; Tom van der Poll
Sequential measurements of chemokines in urosepsis and experimental endotoxemia.
Journal of clinical immunology 1999;19(6):399-405.
1999: Gwenda Pynaert; Johan Grooten; Sander J H van Deventer; Maikel Peppelenbosch
Cysteinyl leukotrienes mediate histamine hypersensitivity ex vivo by increasing histamine receptor numbers.
Molecular medicine (Cambridge, Mass.) 1999;5(10):685-92.
1999: Paul Rutgeerts; Geert D'Haens; Stephan R Targan; Eric A Vasiliauskas; S B Hanauer; Daniel H Present; L Mayer; R A Van Hogezand; T Braakman; KL DeWoody; TF Schaible; Sander J H van Deventer
Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease.
Gastroenterology 1999;117(4):761-9.
1999: Pascale E P Dekkers; Fanny N Lauw; Tessa ten Hove; Anje A Te Velde; P Lumley; D Becherer; Sander J H van Deventer; Tom van der Poll
The effect of a metalloproteinase inhibitor (GI5402) on tumor necrosis factor-alpha (TNF-alpha) and TNF-alpha receptors during human endotoxemia.
Blood 1999;94(7):2252-8.
1999: Pascale E P Dekkers; Marcel Levi; Sander J H van Deventer; Tom van der Poll
Divergent roles of tumor necrosis factor and platelet-activating factor in endotoxin-induced release of monocyte chemoattractant protein 1 and macrophage inflammatory protein 1beta in chimpanzees.
Infection and immunity 1999;67(10):5480-2.
1999: Gijs R van den Brink; S M Bloemers; Bernt van den Blink; Leon Tertoolen; Sander J H van Deventer; Maikel Peppelenbosch
Study of calcium signaling in non-excitable cells.
Microscopy research and technique 1999;46(6):418-33.
1999: Pieter C F Stokkers; Pieter H Reitsma; G N J Tytgat; Sander J H van Deventer
HLA-DR and -DQ phenotypes in inflammatory bowel disease: a meta-analysis.
Gut 1999;45(3):395-401.
1999: Nicole P Juffermans; Annelies Verbon; Sander J H van Deventer; H van Deutekom; John Belisle; M E Ellis; Peter Speelman; Tom van der Poll
Elevated chemokine concentrations in sera of human immunodeficiency virus (HIV)-seropositive and HIV-seronegative patients with tuberculosis: a possible role for mycobacterial lipoarabinomannan.
Infection and immunity 1999;67(8):4295-7.
1999: Fanny N Lauw; Anje A Te Velde; Pascale E P Dekkers; Peter Speelman; johannes aerts; C Erik Hack; Sander J H van Deventer; Tom van der Poll
Activation of mononuclear cells by interleukin-12: an in vivo study in chimpanzees.
Journal of clinical immunology 1999;19(4):231-8.
1999: Tom van der Poll; Sander J H van Deventer
Cytokines and anticytokines in the pathogenesis of sepsis.
Infectious disease clinics of North America 1999;13(2):413-26, ix.
1999: Maikel Peppelenbosch; M Desmedt; Tessa ten Hove; Sander J H van Deventer; Johan Grooten
Lipopolysaccharide regulates macrophage fluid phase pinocytosis via CD14-dependent and CD14-independent pathways.
Blood 1999;93(11):4011-8.
1999: Daniel H Present; Paul Rutgeerts; Stephan R Targan; S B Hanauer; L Mayer; Ruud A van Hogezand; D K Podolsky; Bruce Sands; T Braakman; KL DeWoody; TF Schaible; Sander J H van Deventer
Infliximab for the treatment of fistulas in patients with Crohn's disease.
The New England journal of medicine 1999;340(18):1398-405.
1999: Geert D'Haens; Sander J H van Deventer; R Van Hogezand; D Chalmers; C Kothe; Filip Baert; T Braakman; TF Schaible; Karel Geboes; Paul Rutgeerts
Endoscopic and histological healing with infliximab anti-tumor necrosis factor antibodies in Crohn's disease: A European multicenter trial.
Gastroenterology 1999;116(5):1029-34.
1999: Fanny N Lauw; Pascale E P Dekkers; Anje A Te Velde; Peter Speelman; Marcel Levi; M Kurimoto; C Erik Hack; Sander J H van Deventer; Tom van der Poll
Interleukin-12 induces sustained activation of multiple host inflammatory mediator systems in chimpanzees.
The Journal of infectious diseases 1999;179(3):646-52.
1999: Henri H Versteeg; Paul M P van Bergen en Henegouwen; Sander J H van Deventer; Maikel Peppelenbosch
Cyclooxygenase-dependent signalling: molecular events and consequences.
FEBS letters 1999;445(1):1-5.
1999: Pieter C F Stokkers; K de Heer; AC Leegwater; Pieter H Reitsma; G N J Tytgat; Sander J H van Deventer
Inflammatory bowel disease and the genes for the natural resistance-associated macrophage protein-1 and the interferon-gamma receptor 1.
International journal of colorectal disease 1999;14(1):13-7.
1999: AW van Milligen de Wit; H Kuiper; L Camoglio; J van Bracht; E Anthony Jones; G N J Tytgat; Sander J H van Deventer
Does ursodeoxycholic acid mediate immunomodulatory and anti-inflammatory effects in patients with primary sclerosing cholangitis?
European journal of gastroenterology & hepatology 1999;11(2):129-36.
1999: Annelies Verbon; Nicole P Juffermans; Sander J H van Deventer; Peter Speelman; H van Deutekom; Tom van der Poll
Serum concentrations of cytokines in patients with active tuberculosis (TB) and after treatment.
Clinical and experimental immunology 1999;115(1):110-3.
1999: Lucienne C Lemaire; J B van Lanschot; C P Stoutenbeek; Sander J H van Deventer; J Dankert; H Oosting; Dirk J Gouma
Thoracic duct in patients with multiple organ failure: no major route of bacterial translocation.
Annals of surgery 1999;229(1):128-36.
1998: Sander J H van Deventer
Cytokines and mucosal inflammatory response in Crohn's disease.
The European journal of surgery = Acta chirurgica 1998;164(12):897-901.
1998: Nicole P Juffermans; Annelies Verbon; Sander J H van Deventer; Wim A Buurman; H van Deutekom; Peter Speelman; Tom van der Poll
Serum concentrations of lipopolysaccharide activity-modulating proteins during tuberculosis.
The Journal of infectious diseases 1998;178(6):1839-42.
1998: A Manten; Robbert J De Winter; MC Minnema; Hugo ten Cate; J G Lijmer; R Adams; Ron J G Peters; Sander J H van Deventer
Procoagulant and proinflammatory activity in acute coronary syndromes.
Cardiovascular research 1998;40(2):389-95.
1998: Lucienne C Lemaire; Tom van der Poll; J J B van Lanschot; Erik Endert; Wim A Buurman; Sander J H van Deventer; Dirk J Gouma
Minimally invasive surgery induces endotoxin-tolerance in the absence of detectable endotoxemia.
Journal of clinical immunology 1998;18(6):414-20.
1998: Luisa Camoglio; Anje A Te Velde; A J Tigges; P K Das; Sander J H van Deventer
Altered expression of interferon-gamma and interleukin-4 in inflammatory bowel disease.
Inflammatory bowel diseases 1998;4(4):285-90.
1998: Jan M Prins; Fanny N Lauw; B H F Derkx; Peter Speelman; Ed J Kuijper; Jacob Dankert; Sander J H van Deventer
Endotoxin release and cytokine production in acute and chronic meningococcaemia.
Clinical and experimental immunology 1998;114(2):215-9.
1998: MC Minnema; D Pajkrt; W A Wuillemin; D Roem; W K Bleeker; Marcel Levi; Sander J H van Deventer; C Erik Hack; Hugo ten Cate
Activation of clotting factor XI without detectable contact activation in experimental human endotoxemia.
Blood 1998;92(9):3294-301.
1998: HM van Dullemen; Gertjan Wolbink; Peter C Wever; T van der Poll; C Erik Hack; G N J Tytgat; Sander J H van Deventer
Reduction of circulating secretory phospholipase A2 levels by anti-tumor necrosis factor chimeric monoclonal antibody in patients with severe Crohn's disease. Relation between tumor necrosis factor and secretory phospholipase A2 in healthy humans and in active Crohn's disease.
Scandinavian journal of gastroenterology 1998;33(10):1094-8.
1998: John Meenan; J Spaans; TA Grool; Karen Lammers; Steven T Pals; G N Tytgat; Sander J H van Deventer
Variation in gut-homing CD27-negative lymphocytes in inflammatory colon disease.
Scandinavian journal of immunology 1998;48(3):318-23.
1998: Lucienne C Lemaire; J J B van Lanschot; Tom van der Poll; Wim A Buurman; Sander J H van Deventer; Dirk J Gouma
Lymph of patients with a systemic inflammatory response syndrome inhibits lipopolysaccharide-induced cytokine production.
The Journal of infectious diseases 1998;178(3):883-6.
1998: Dariusz P Olszyna; Jan M Prins; B Buis; Sander J H van Deventer; Peter Speelman; Tom van der Poll
Levels of inhibitors of tumor necrosis factor alpha and interleukin 1beta in urine and sera of patients with urosepsis.
Infection and immunity 1998;66(8):3527-34.
1998: Pieter C F Stokkers; B E van Aken; N Basoski; Pieter H Reitsma; G N J Tytgat; Sander J H van Deventer
Five genetic markers in the interleukin 1 family in relation to inflammatory bowel disease.
Gut 1998;43(1):33-9.
1998: TA Grool; H van Dullemen; John Meenan; F Koster; F J ten Kate; LeBeaut Pierre Alexandre; G N J Tytgat; Sander J H van Deventer
Anti-inflammatory effect of interleukin-10 in rabbit immune complex-induced colitis.
Scandinavian journal of gastroenterology 1998;33(7):754-8.
1998: Marcus Schultz; Peter Speelman; Sebastian A J Zaat; Sander J H van Deventer; Tom van der Poll
Erythromycin inhibits tumor necrosis factor alpha and interleukin 6 production induced by heat-killed Streptococcus pneumoniae in whole blood.
Antimicrobial agents and chemotherapy 1998;42(7):1605-9.
1998: Evert de Jonge; Marcel Levi; CP Stoutenbeek; Sander J H van Deventer
Current drug treatment strategies for disseminated intravascular coagulation.
Drugs 1998;55(6):767-77.
1998: Nicole P Juffermans; Annelies Verbon; Sander J H van Deventer; H van Deutekom; Peter Speelman; Tom van der Poll
Tumor necrosis factor and interleukin-1 inhibitors as markers of disease activity of tuberculosis.
American journal of respiratory and critical care medicine 1998;157(4 Pt 1):1328-31.
1998: C van Montfrans; Luisa Camoglio; Sander J H van Deventer
Immunotherapy of Crohn's disease.
Mediators of inflammation 1998;7(3):149-52.
1998: Tom van der Poll; Sander J H van Deventer
The role of interleukin 6 in endotoxin-induced inflammatory responses.
Progress in clinical and biological research 1998;397():365-77.
1998: HM van Dullemen; E de Jong; F Slors; G N J Tytgat; Sander J H van Deventer
Treatment of therapy-resistant perineal metastatic Crohn's disease after proctectomy using anti-tumor necrosis factor chimeric monoclonal antibody, cA2: report of two cases.
Diseases of the colon and rectum 1998;41(1):98-102.
1998: Lucienne C Lemaire; Sander J H van Deventer; J J B van Lanschot; John Meenan; Dirk J Gouma
Phenotypical characterization of cells in the thoracic duct of patients with and without systemic inflammatory response syndrome and multiple organ failure.
Scandinavian journal of immunology 1998;47(1):69-75.
1997: Robbert J De Winter; A Manten; Y P de Jong; R Adams; Sander J H van Deventer; Kong I Lie
Interleukin 8 released after acute myocardial infarction is mainly bound to erythrocytes.
Heart (British Cardiac Society) 1997;78(6):598-602.
1997: Sander J H van Deventer
Review article: Chemokine production by intestinal epithelial cells: a therapeutic target in inflammatory bowel disease?
Alimentary pharmacology & therapeutics 1997;11 Suppl 3():116-20; discussion 120-1.
1997: D W Hommes; HM van Dullemen; Marcel Levi; A van der Ende; J Woody; G N J Tytgat; Sander J H van Deventer
Beneficial effect of treatment with a monoclonal anti-tumor necrosis factor-alpha antibody on markers of coagulation and fibrinolysis in patients with active Crohn's disease.
Haemostasis 1997;27(6):269-77.
1997: Stephan R Targan; S B Hanauer; Sander J H van Deventer; L Mayer; Daniel H Present; T Braakman; KL DeWoody; TF Schaible; Paul Rutgeerts
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group.
The New England journal of medicine 1997;337(15):1029-35.
1997: Lucienne C Lemaire; J J B van Lanschot; C P Stoutenbeek; Sander J H van Deventer; C L Wells; Dirk J Gouma
Bacterial translocation in multiple organ failure: cause or epiphenomenon still unproven.
The British journal of surgery 1997;84(10):1340-50.
1997: Dasja Pajkrt; A Manten; Tom van der Poll; MM Tiel-van Buul; J Jansen; J Wouter ten Cate; Sander J H van Deventer
Modulation of cytokine release and neutrophil function by granulocyte colony-stimulating factor during endotoxemia in humans.
Blood 1997;90(4):1415-24.
1997: W B Slot; F W Merkus; Sander J H van Deventer; G N J Tytgat
Normalization of plasma vitamin B12 concentration by intranasal hydroxocobalamin in vitamin B12-deficient patients.
Gastroenterology 1997;113(2):430-3.
1997: JW ten Cate; Tom van der Poll; Marcel Levi; Hugo ten Cate; Sander J H van Deventer
Cytokines: triggers of clinical thrombotic disease.
Thrombosis and haemostasis 1997;78(1):415-9.
1997: CG Wu; Frans J Hoek; Maarten Groenink; PH Reitsma; Sander J H van Deventer; Robert Chamuleau
Correlation of repressed transcription of alpha-tocopherol transfer protein with serum alpha-tocopherol during hepatocarcinogenesis.
International journal of cancer. Journal international du cancer 1997;71(4):686-90.
1997: Dasja Pajkrt; Tom van der Poll; Marcel Levi; David L Cutler; Melton Affrime; A van den Ende; JW ten Cate; Sander J H van Deventer
Interleukin-10 inhibits activation of coagulation and fibrinolysis during human endotoxemia.
Blood 1997;89(8):2701-5.
1997: Dasja Pajkrt; Luisa Camoglio; M C Tiel-van Buul; Kora de Bruin; David L Cutler; Melton Affrime; G Rikken; Tom van der Poll; JW ten Cate; Sander J H van Deventer
Attenuation of proinflammatory response by recombinant human IL-10 in human endotoxemia: effect of timing of recombinant human IL-10 administration.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(8):3971-7.
1997: Sander J H van Deventer
Tumour necrosis factor and Crohn's disease.
Gut 1997;40(4):443-8.
1997: CG Wu; Willem Boers; P R Reitsma; Sander J H van Deventer; Robert Chamuleau
Overexpression of prothymosin alpha, concomitant with c-myc, during rat hepatic carcinogenesis.
Biochemical and biophysical research communications 1997;232(3):817-21.
1997: A Stronkhorst; S Radema; S L Yong; H Bijl; I J ten Berge; G N J Tytgat; Sander J H van Deventer
CD4 antibody treatment in patients with active Crohn's disease: a phase 1 dose finding study.
Gut 1997;40(3):320-7.
1997: Dasja Pajkrt; PG Lerch; Tom van der Poll; Marcel Levi; M Illi; JE Doran; B Arnet; A van den Ende; JW ten Cate; Sander J H van Deventer
Differential effects of reconstituted high-density lipoprotein on coagulation, fibrinolysis and platelet activation during human endotoxemia.
Thrombosis and haemostasis 1997;77(2):303-7.
1997: John Meenan; J Spaans; TA Grool; Steven T Pals; G N J Tytgat; Sander J H van Deventer
Altered expression of alpha 4 beta 7, a gut homing integrin, by circulating and mucosal T cells in colonic mucosal inflammation.
Gut 1997;40(2):241-6.
1997: CG Wu; Nagy A Habib; Ragai R Mitry; PH Reitsma; Sander J H van Deventer; Robert Chamuleau
Overexpression of hepatic prothymosin alpha, a novel marker for human hepatocellular carcinoma.
British journal of cancer 1997;76(9):1199-204.
1997: H van Dullemen; John Meenan; A Stronkhorst; G N J Tytgat; Sander J H van Deventer
Mediators of mucosal inflammation: implications for therapy.
Scandinavian journal of gastroenterology. Supplement 1997;223():92-8.
1997: CG Wu; Maarten Groenink; A Bosma; PH Reitsma; Sander J H van Deventer; Robert Chamuleau
Rat ferritin-H: cDNA cloning, differential expression and localization during hepatocarcinogenesis.
Carcinogenesis 1997;18(1):47-52.
1997: Jan M Prins; Peter Speelman; Ed J Kuijper; Jacob Dankert; Sander J H van Deventer
No increase in endotoxin release during antibiotic killing of meningococci.
The Journal of antimicrobial chemotherapy 1997;39(1):13-8.
1997: Marcel Levi; Tom van der Poll; Hugo ten Cate; Sander J H van Deventer
The cytokine-mediated imbalance between coagulant and anticoagulant mechanisms in sepsis and endotoxaemia.
European journal of clinical investigation 1997;27(1):3-9.
1996: H H Derkx; J van den Hoek; WK Redekop; R P Bijlmer; Sander J H van Deventer; Patrick Bossuyt
Meningococcal disease: a comparison of eight severity scores in 125 children.
Intensive care medicine 1996;22(12):1433-41.
1996: F Snijders; John Meenan; Bernt van den Blink; Sander J H van Deventer; F J ten Kate
Duodenal intraepithelial and lamina propria T lymphocytes in human immunodeficiency virus-infected patients with and without diarrhoea.
Scandinavian journal of gastroenterology 1996;31(12):1176-81.
1996: D W Hommes; John Meenan; S Dijkhuizen; F J Ten Kate; G N J Tytgat; Sander J H van Deventer
Efficacy of recombinant granulocyte colony-stimulating factor (rhG-CSF) in experimental colitis.
Clinical and experimental immunology 1996;106(3):529-33.
1996: Dasja Pajkrt; JE Doran; F Koster; PG Lerch; B Arnet; Tom van der Poll; JW ten Cate; Sander J H van Deventer
Antiinflammatory effects of reconstituted high-density lipoprotein during human endotoxemia.
The Journal of experimental medicine 1996;184(5):1601-8.
1996: Alessandra Borchiellini; Karin Fijnvandraat; JW ten Cate; D Pajkrt; Sander J H van Deventer; G Pasterkamp; F Meijer-Huizinga; L Zwart-Huinink; Jan Voorberg; Jan A van Mourik
Quantitative analysis of von Willebrand factor propeptide release in vivo: effect of experimental endotoxemia and administration of 1-deamino-8-D-arginine vasopressin in humans.
Blood 1996;88(8):2951-8.
1996: John Meenan; D W Hommes; M Mevissen; S Dijkhuizen; H Soule; M Moyle; Harry R Büller; F W ten Kate; G N J Tytgat; Sander J H van Deventer
Attenuation of the inflammatory response in an animal colitis model by neutrophil inhibitory factor, a novel beta 2-integrin antagonist.
Scandinavian journal of gastroenterology 1996;31(8):786-91.
1996: M A von der Möhlen; Tom van der Poll; J Jansen; Marcel Levi; Sander J H van Deventer
Release of bactericidal/permeability-increasing protein in experimental endotoxemia and clinical sepsis. Role of tumor necrosis factor.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(12):4969-73.
1996: John Meenan; T A Grool; D W Hommes; S Dijkhuizen; F J ten Kate; M Wood; M Whittaker; G N J Tytgat; Sander J H van Deventer
Lexipafant (BB-882), a platelet activating factor receptor antagonist, ameliorates mucosal inflammation in an animal model of colitis.
European journal of gastroenterology & hepatology 1996;8(6):569-73.
1996: E de Jong; HM van Dullemen; J F M Slors; P Dekkers; Sander J H van Deventer; G N J Tytgat
Correlation between early recurrence and reoperation after ileocolonic resection in Crohn's disease: a prospective study.
Journal of the American College of Surgeons 1996;182(6):503-8.
1996: D W Hommes; John Meenan; Masja de Haas; F J ten Kate; Albert E G Kr von dem Borne; G N J Tytgat; Sander J H van Deventer
Soluble Fc gamma receptor III (CD 16) and eicosanoid concentrations in gut lavage fluid from patients with inflammatory bowel disease: reflection of mucosal inflammation.
Gut 1996;38(4):564-7.
1996: H Monajemi; John Meenan; R Lamping; D O Obradov; S A Radema; P W Trown; G N Tytgat; Sander J H van Deventer
Inflammatory bowel disease is associated with increased mucosal levels of bactericidal/permeability-increasing protein.
Gastroenterology 1996;110(3):733-9.
1996: John Meenan; M Mevissen; H Monajemi; S A Radema; H R Soule; M Moyle; G N J Tytgat; Sander J H van Deventer
Mechanisms underlying neutrophil adhesion to apical epithelial membranes.
Gut 1996;38(2):201-5.
1996: John Meenan; D O Obradov; HM van Dullemen; G N J Tytgat; Sander J H van Deventer
Use of buffered formaldehyde in the enzymatic digestion of inflamed mucosa.
Journal of clinical pathology 1996;49(2):177-9.
1996: Sander J H van Deventer; Luisa Camoglio
Monoclonal antibody therapy of inflammatory bowel disease.
Alimentary pharmacology & therapeutics 1996;10 Suppl 2():107-11; discussion 112.
1996: Tom van der Poll; J Jansen; Marcel Levi; Hugo ten Cate; C Erik Hack; Lucien A Aarden; JW ten Cate; Sander J H van Deventer
Interleukin 10 release during endotoxaemia in chimpanzees: role of platelet-activating factor and interleukin 6.
Scandinavian journal of immunology 1996;43(1):122-5.
1995: A N Kimmings; Sander J H van Deventer; Huug Obertop; Erik A J Rauws; Dirk J Gouma
Inflammatory and immunologic effects of obstructive jaundice: pathogenesis and treatment.
Journal of the American College of Surgeons 1995;181(6):567-81.
1995: H H Derkx; Ed J Kuijper; Cees A P Fijen; M Jak; Jacob Dankert; Sander J H van Deventer
Inherited complement deficiency in children surviving fulminant meningococcal septic shock.
European journal of pediatrics 1995;154(9):735-8.
1995: Jan M Prins; M A van Agtmael; E J Kuijper; Sander J H van Deventer; Peter Speelman
Antibiotic-induced endotoxin release in patients with gram-negative urosepsis: a double-blind study comparing imipenem and ceftazidime.
The Journal of infectious diseases 1995;172(3):886-91.
1995: K F Bruin; D W Hommes; J Jansen; G N J Tytgat; J Wouter ten Cate; Sander J H van Deventer
Modulation of cytokine release from human monocytes by drugs used in the therapy of inflammatory bowel diseases.
European journal of gastroenterology & hepatology 1995;7(8):791-5.
1995: HM van Dullemen; Sander J H van Deventer; D W Hommes; H A Bijl; J Jansen; G N J Tytgat; J Woody
Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2).
Gastroenterology 1995;109(1):129-35.
1995: M A von der Möhlen; Sander J H van Deventer; Marcel Levi; B van den Ende; N I Wedel; B J Nelson; N Friedmann; JW ten Cate
Inhibition of endotoxin-induced activation of the coagulation and fibrinolytic pathways using a recombinant endotoxin-binding protein (rBPI23).
Blood 1995;85(12):3437-43.
1995: AW van Milligen de Wit; Sander J H van Deventer; G N J Tytgat
Immunogenetic aspects of primary sclerosing cholangitis: implications for therapeutic strategies.
The American journal of gastroenterology 1995;90(6):893-900.
1995: J M Prins; E J Kuijper; M L Mevissen; Peter Speelman; Sander J H van Deventer
Release of tumor necrosis factor alpha and interleukin 6 during antibiotic killing of Escherichia coli in whole blood: influence of antibiotic class, antibiotic concentration, and presence of septic serum.
Infection and immunity 1995;63(6):2236-42.
1995: F Snijders; Sander J H van Deventer; J F Bartelsman; P den Otter; J Jansen; M L Mevissen; Tom Van Gool; Sven A Danner; Peter Reiss
Diarrhoea in HIV-infected patients: no evidence of cytokine-mediated inflammation in jejunal mucosa.
AIDS (London, England) 1995;9(4):367-73.
1995: Tom van der Poll; Marcel Levi; Hugo ten Cate; J Jansen; Bart J Biemond; B L Haagmans; A Eerenberg; Sander J H van Deventer; C Erik Hack; JW ten Cate
Effect of postponed treatment with an anti-tumour necrosis factor (TNF) F(ab')2 fragment on endotoxin-induced cytokine and neutrophil responses in chimpanzees.
Clinical and experimental immunology 1995;100(1):21-5.
1995: Pieter C F Stokkers; L Camoglio; Sander J H van Deventer
Tumor necrosis factor (TNF) in inflammatory bowel disease: gene polymorphisms, animal models, and potential for anti-TNF therapy.
Journal of inflammation 1995;47(1-2):97-103.
1995: Robbert J De Winter; M A von der Möhlen; H van Lieshout; N Wedel; B Nelson; N Friedmann; B J Delemarre; Sander J H van Deventer
Recombinant endotoxin-binding protein (rBPI23) attenuates endotoxin-induced circulatory changes in humans.
Journal of inflammation 1995;45(3):193-206.
1995: B Derkx; A Marchant; M Goldman; R Bijlmer; Sander J H van Deventer
High levels of interleukin-10 during the initial phase of fulminant meningococcal septic shock.
The Journal of infectious diseases 1995;171(1):229-32.
1995: J Jansen; Tom van der Poll; Marcel Levi; Hugo ten Cate; H Gallati; JW ten Cate; Sander J H van Deventer
Inhibition of the release of soluble tumor necrosis factor receptors in experimental endotoxemia by an anti-tumor necrosis factor-alpha antibody.
Journal of clinical immunology 1995;15(1):45-50.
1995: Karin Fijnvandraat; B Derkx; Marjolein Peters; R Bijlmer; Augueste Sturk; Martin H Prins; Sander J H van Deventer; JW ten Cate
Coagulation activation and tissue necrosis in meningococcal septic shock: severely reduced protein C levels predict a high mortality.
Thrombosis and haemostasis 1995;73(1):15-20.
1995: S A Radema; G N Tytgat; Sander J H van Deventer
In situ detection of interleukin-1 beta and interleukin 8 in biopsy specimens from patients with ulcerative colitis.
Advances in experimental medicine and biology 1995;371B():1297-9.
1994: Tom van der Poll; J Jansen; Marcel Levi; Hugo ten Cate; JW ten Cate; Sander J H van Deventer
Regulation of interleukin 10 release by tumor necrosis factor in humans and chimpanzees.
The Journal of experimental medicine 1994;180(5):1985-8.
1994: Tom van der Poll; J Jansen; Erik Endert; Hans P Sauerwein; Sander J H van Deventer
Noradrenaline inhibits lipopolysaccharide-induced tumor necrosis factor and interleukin 6 production in human whole blood.
Infection and immunity 1994;62(5):2046-50.
1994: L A Noach; N B Bosma; J Jansen; F J Hoek; Sander J H van Deventer; G N J Tytgat
Mucosal tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-8 production in patients with Helicobacter pylori infection.
Scandinavian journal of gastroenterology 1994;29(5):425-9.
1994: Tom van der Poll; Marcel Levi; C Erik Hack; Hugo ten Cate; Sander J H van Deventer; A J Eerenberg; Els R de Groot; J Jansen; H Gallati; Harry R Büller
Elimination of interleukin 6 attenuates coagulation activation in experimental endotoxemia in chimpanzees.
The Journal of experimental medicine 1994;179(4):1253-9.
1994: M H Godfried; Tom van der Poll; Gerrit Jan Weverling; Jan W Mulder; J Jansen; Sander J H van Deventer; Hans P Sauerwein
Soluble receptors for tumor necrosis factor as predictors of progression to AIDS in asymptomatic human immunodeficiency virus type 1 infection.
The Journal of infectious diseases 1994;169(4):739-45.
1994: Tom van der Poll; Sander J H van Deventer; Hugo ten Cate; Marcel Levi; JW ten Cate
Tumor necrosis factor is involved in the appearance of interleukin-1 receptor antagonist in endotoxemia.
The Journal of infectious diseases 1994;169(3):665-7.
1994: Karen Lammers; J Jansen; P B Bijlsma; M Ceska; G N J Tytgat; C L Laboisse; Sander J H van Deventer
Polarised interleukin 8 secretion by HT 29/19A cells.
Gut 1994;35(3):338-42.
1994: B Kuipers; Tom van der Poll; Marcel Levi; Sander J H van Deventer; Hugo ten Cate; Y Imai; C Erik Hack; JW ten Cate
Platelet-activating factor antagonist TCV-309 attenuates the induction of the cytokine network in experimental endotoxemia in chimpanzees.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(5):2438-46.
1994: Tom van der Poll; Marcel Levi; Sander J H van Deventer; Hugo ten Cate; B L Haagmans; Bart J Biemond; Harry R Büller; C Erik Hack; JW ten Cate
Differential effects of anti-tumor necrosis factor monoclonal antibodies on systemic inflammatory responses in experimental endotoxemia in chimpanzees.
Blood 1994;83(2):446-51.
1994: Marcel Levi; Hugo ten Cate; K A Bauer; Tom van der Poll; T S Edgington; Harry R Büller; Sander J H van Deventer; C Erik Hack; JW ten Cate; R D Rosenberg
Inhibition of endotoxin-induced activation of coagulation and fibrinolysis by pentoxifylline or by a monoclonal anti-tissue factor antibody in chimpanzees.
The Journal of clinical investigation 1994;93(1):114-20.
1994: Tom van der Poll; Marcel Levi; Hugo ten Cate; Sander J H van Deventer
The role of tumor necrosis factor in systemic inflammatory responses in primate endotoxemia.
Progress in clinical and biological research 1994;388():425-33.
1994: J Jansen; Tom van der Poll; Sander J H van Deventer
Endotoxin and the release of tumor necrosis factor receptors.
Progress in clinical and biological research 1994;388():383-97.
1994: Karin Fijnvandraat; Marjolein Peters; B Derkx; Sander J H van Deventer; JW ten Cate
Endotoxin induced coagulation activation and protein C reduction in meningococcal septic shock.
Progress in clinical and biological research 1994;388():247-54.
1994: Hugo ten Cate; Marcel Levi; Tom van der Poll; Bart J Biemond; Sander J H van Deventer; H R Buller; JW ten Cate
Inhibition of extrinsic coagulation activation in endotoxemia; therapeutic implications.
Progress in clinical and biological research 1994;388():215-9.
1993: Peter Portegies; M H Godfried; R Q Hintzen; J Stam; Tom van der Poll; Margreet Bakker; Sander J H van Deventer; René A W van Lier; Jaap Goudsmit
Low levels of specific T cell activation marker CD27 accompanied by elevated levels of markers for non-specific immune activation in the cerebrospinal fluid of patients with AIDS dementia complex.
Journal of neuroimmunology 1993;48(2):241-7.
1993: Tom van der Poll; J Jansen; D van Leenen; M von der Möhlen; Marcel Levi; Hugo ten Cate; H Gallati; JW ten Cate; Sander J H van Deventer
Release of soluble receptors for tumor necrosis factor in clinical sepsis and experimental endotoxemia.
The Journal of infectious diseases 1993;168(4):955-60.
1993: C H Wortel; Sander J H van Deventer; L A Aarden; N J Lygidakis; H R Büller; F J Hoek; J Horikx; J W ten Cate
Interleukin-6 mediates host defense responses induced by abdominal surgery.
Surgery 1993;114(3):564-70.
1993: D van Leenen; Tom van der Poll; Marcel Levi; Hugo ten Cate; Sander J H van Deventer; C Erik Hack; Lucien A Aarden; JW ten Cate
Pentoxifylline attenuates neutrophil activation in experimental endotoxemia in chimpanzees.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(4):2318-25.
1993: B Derkx; J Taminiau; S Radema; A Stronkhorst; C Wortel; G N J Tytgat; Sander J H van Deventer
Tumour-necrosis-factor antibody treatment in Crohn's disease.
Lancet 1993;342(8864):173-4.
1993: Hugo ten Cate; D P M Brandjes; H J Wolters; Sander J H van Deventer
Disseminated intravascular coagulation: pathophysiology, diagnosis, and treatment.
New horizons (Baltimore, Md.) 1993;1(2):312-23.
1993: Sander J H van Deventer; M Hart; Tom van der Poll; C Erik Hack; L A Aarden
Endotoxin and tumor necrosis factor-alpha-induced interleukin-8 release in humans.
The Journal of infectious diseases 1993;167(2):461-54.
1993: M H Godfried; Tom van der Poll; J Jansen; J A Romijin; J K Schattenkerk; Erik Endert; Sander J H van Deventer; Hans P Sauerwein
Soluble receptors for tumour necrosis factor: a putative marker of disease progression in HIV infection.
AIDS (London, England) 1993;7(1):33-6.
1992: C H Wortel; M A von der Möhlen; Sander J H van Deventer; C L Sprung; M Jastremski; M J Lubbers; C R Smith; I E Allen; JW ten Cate
Effectiveness of a human monoclonal anti-endotoxin antibody (HA-1A) in gram-negative sepsis: relationship to endotoxin and cytokine levels.
The Journal of infectious diseases 1992;166(6):1367-74.
1992: Tom van der Poll; Sander J H van Deventer; G Pasterkamp; Jan A van Mourik; Harry R Büller; JW ten Cate
Tumor necrosis factor induces von Willebrand factor release in healthy humans.
Thrombosis and haemostasis 1992;67(6):623-6.
1992: Tom van der Poll; Sander J H van Deventer; C Erik Hack; Gertjan Wolbink; Lucien A Aarden; Harry R Büller; JW ten Cate
Effects on leukocytes after injection of tumor necrosis factor into healthy humans.
Blood 1992;79(3):693-8.
1992: A Stronkhorst; G N J Tytgat; Sander J H van Deventer
CD4 antibody treatment in Crohn's disease.
Scandinavian journal of gastroenterology. Supplement 1992;194():61-5.
1991: Tom van der Poll; Sander J H van Deventer; H R Büller; A Sturk; JW ten Cate
Comparison of the early dynamics of systemic prostacyclin release after administration of tumor necrosis factor and endotoxin to healthy humans.
The Journal of infectious diseases 1991;164(3):599-601.
1991: Tom van der Poll; Marcel Levi; Harry R Büller; Sander J H van Deventer; J P de Boer; C Erik Hack; JW ten Cate
Fibrinolytic response to tumor necrosis factor in healthy subjects.
The Journal of experimental medicine 1991;174(3):729-32.
1991: Tom van der Poll; Sander J H van Deventer; Harry R Büller; Augueste Sturk; JW ten Cate
Comparison of the early dynamics of coagulation activation after injection of endotoxin and tumor necrosis factor in healthy humans.
Progress in clinical and biological research 1991;367():55-60.
1991: C H Wortel; E J Ziegler; Sander J H van Deventer
Therapy of gram-negative sepsis in man with anti-endotoxin antibodies: a review.
Progress in clinical and biological research 1991;367():161-78.
1991: Sander J H van Deventer; C E Hack; C E Wolbink; H J Voermans; R J Strack van Schijindel; JW ten Cate; L G Thijs
Endotoxin-induced neutrophil activation--the role of complement revisited.
Progress in clinical and biological research 1991;367():101-9.
1990: Tom van der Poll; Harry R Büller; Hugo ten Cate; C H Wortel; K A Bauer; Sander J H van Deventer; C Erik Hack; Hans P Sauerwein; R D Rosenberg; JW ten Cate
Activation of coagulation after administration of tumor necrosis factor to normal subjects.
The New England journal of medicine 1990;322(23):1622-7.
1990: I de Vries; Sander J H van Deventer; J Debets; H R Buller; JW ten Cate; W Pauw; L W Statius van Eps; A Sturk
Endotoxin-induced cytokines in human septicemia.
Advances in experimental medicine and biology 1990;256():635-40.
1988: G N J Tytgat; Sander J H van Deventer
Pouchitis.
International journal of colorectal disease 1988;3(4):226-8.
1988: Sander J H van Deventer; A Knepper; J Landsman; J Lawson; JW ten Cate; H R Buller; A Sturk; W Pauw
Endotoxins in portal blood.
Hepato-gastroenterology 1988;35(5):223-5.
1988: Sander J H van Deventer; H R Buller; JW ten Cate; A Sturk; W Pauw
Endotoxaemia: an early predictor of septicaemia in febrile patients.
Lancet 1988;1(8586):605-9.
1988: Sander J H van Deventer; I de Vries; L W Statius van Eps; W Pauw; H R Büller; A Sturk; JW ten Cate
Endotoxemia, bacteremia and urosepsis.
Progress in clinical and biological research 1988;272():213-24.
1987: Sander J H van Deventer; W Pauw; JW ten Cate; M E Janssen; H R Büller; A Sturk
Clinical evaluation in febrile patients of an optimized endotoxin assay in blood.
Progress in clinical and biological research 1987;231():489-99.