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Jacques van Dongen

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Gertjan J Driessen; Asgeir Haraldsson; Hanna Ijspeert; Malcolm A Taylor; Margreet Trip; Michiel van der Flier; Marcel van Deuren; Jacques J M van Dongen; Menno van Zelm; Mijke M M Verhagen; Adilia Warris; Corry M R Weemaes; Nico Wulffraat; Mirjam van der Burg
Antibody deficiency in patients with ataxia telangiectasia is caused by disturbed B- and T-cell homeostasis and reduced immune repertoire diversity.
Tom Missotten; Dennis Tielemans; Jacques J M van Dongen; P Martin van Hagen; Ellen G van Lochem; G Seerp Baarsma; Jacolien E Bromberg; Anton W Langerak
Multicolor flowcytometric immunophenotyping is a valuable tool for detection of intraocular lymphoma.
Kim van der Weerd; Jacques J M van Dongen; P Martin van Hagen; Francien H van Nederveen; Ad J J C Bogers; Willem A Dik; Anton W Langerak; Alexander P W M Maat; Benjamin Schrijver; Frank J T Staal
Combined TCRG and TCRA TREC analysis reveals increased peripheral T-lymphocyte but constant intra-thymic proliferative history upon ageing.

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All Publications

2013: Gertjan J Driessen; Asgeir Haraldsson; Hanna Ijspeert; Malcolm A Taylor; Margreet Trip; Michiel van der Flier; Marcel van Deuren; Jacques J M van Dongen; Menno van Zelm; Mijke M M Verhagen; Adilia Warris; Corry M R Weemaes; Nico Wulffraat; Mirjam van der Burg
Antibody deficiency in patients with ataxia telangiectasia is caused by disturbed B- and T-cell homeostasis and reduced immune repertoire diversity.
The Journal of allergy and clinical immunology 2013;131(5):1367-75.e9.
2013: Tom Missotten; Dennis Tielemans; Jacques J M van Dongen; P Martin van Hagen; Ellen G van Lochem; G Seerp Baarsma; Jacolien E Bromberg; Anton W Langerak
Multicolor flowcytometric immunophenotyping is a valuable tool for detection of intraocular lymphoma.
Ophthalmology 2013;120(5):991-6.
2013: Kim van der Weerd; Jacques J M van Dongen; P Martin van Hagen; Francien H van Nederveen; Ad J J C Bogers; Willem A Dik; Anton W Langerak; Alexander P W M Maat; Benjamin Schrijver; Frank J T Staal
Combined TCRG and TCRA TREC analysis reveals increased peripheral T-lymphocyte but constant intra-thymic proliferative history upon ageing.
Molecular immunology 2013;53(3):302-12.
2013: Menno van Zelm; Magdalena A Berkowska; Mirjam van der Burg; Jacques J M van Dongen
Real-time quantitative (RQ-)PCR approach to quantify the contribution of proliferation to B lymphocyte homeostasis.
Methods in molecular biology (Clifton, N.J.) 2013;979():133-45.
2013: Christiane Pott; Matthias Ritgen; Vincent H J van der Velden; Jacques J M van Dongen; Monika Brüggemann; Michael Kneba
MRD detection in B-cell non-Hodgkin lymphomas using Ig gene rearrangements and chromosomal translocations as targets for real-time quantitative PCR.
Methods in molecular biology (Clifton, N.J.) 2013;971():175-200.
2013: Menno van Zelm; Magdalena A Berkowska; Jacques J M van Dongen
Studying the replication history of human B lymphocytes by real-time quantitative (RQ)-PCR.
Methods in molecular biology (Clifton, N.J.) 2013;971():113-22.
2012: Barbara Piątosa; Katarzyna Siewiera; Mirjam van der Burg; Jacques J M van Dongen; Krystyna H Chrzanowska; Anton W Langerak; Malgorzata Pac; Ewa Bernatowska
The defect in humoral immunity in patients with Nijmegen breakage syndrome is explained by defects in peripheral B lymphocyte maturation.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2012;81(10):835-42.
2012: Nicole S D Larmonie; Jules P P Meijerink; V H J van der Velden; Jacques J M van Dongen; Berna Beverloo; Willem A Dik; Patricia G Hoogeveen; Anton Langerak
Correct interpretation of T-ALL oncogene expression relies on normal human thymocyte subsets as reference material.
British journal of haematology 2012;157(1):142-6.
2012: Kim van der Weerd; Jacques J M van Dongen; Astrid van Huisstede; Willem A Dik; Hemmo Drexhage; Rosalie M Kiewiet; Anton W Langerak; Benjamin Schrijver; Dave H Schweitzer; Frank J T Staal; Maarten O van Aken; Aart-Jan van der Lelij; P Martin van Hagen
Morbidly obese human subjects have increased peripheral blood CD4+ T cells with skewing toward a Treg- and Th2-dominated phenotype.
Diabetes 2012;61(2):401-8.
2012: Machteld M Tiemessen; Jacques J M van Dongen; Miranda R M Baert; Martijn Brugman; Hans Clevers; Farbod Famili; Jules P P Meijerink; Ugur Ozbek; Daniela C F Salvatori; Tom Schonewille; Frank J T Staal
The nuclear effector of Wnt-signaling, Tcf1, functions as a T-cell-specific tumor suppressor for development of lymphomas.
PLoS biology 2012;10(11):e1001430.
2011: Tiago C Luis; Brigitta A E Naber; Paul P C Roozen; Martijn Brugman; Edwin F E de Haas; Willem E Fibbe; Riccardo Fodde; Mehrnaz Ghazvini; Jacques J M van Dongen; Frank Staal
Canonical wnt signaling regulates hematopoiesis in a dosage-dependent fashion.
Cell stem cell 2011;9(4):345-56.
2011: Martin Schrappe; André Schrauder; Maria Grazia Valsecchi; Jacques J M van Dongen; Karl Welte; Martin Zimmermann; Maurizio Aricò; Claus R Bartram; Giuseppe Basso; Andrea Biondi; Barbara Buldini; Giovanni Cazzaniga; Michael Dworzak; Helmut Gadner; Thomas Klingebiel; Rolf Koehler; Franco Locatelli; Chiara Messina; Anja Möricke; Renate Panzer-Grümayer; Rosanna Parasole; Richard Ratei; Alfred Reiter; Beat W Schäfer; Valentino Conter
Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study.
Blood 2011;118(8):2077-84.
2011: Magdalena A Berkowska; Katharina Biermann; Vasilis Bikos; Andrea Cerutti; Gertjan J A Driessen; Christina Grosserichter-Wagener; Bing He; Johan F Lange; Kostas Stamatopoulos; Mirjam van der Burg; Jacques J M van Dongen; Menno van Zelm
Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways.
Blood 2011;118(8):2150-8.
2011: Sonja E Nodland; Nisha Shah; Jacques J M van Dongen; Anna A Bajer; Magdalena A Berkowska; Dick de Ridder; Tucker W LeBien; Menno van Zelm
IL-7R expression and IL-7 signaling confer a distinct phenotype on developing human B-lineage cells.
Blood 2011;118(8):2116-27.
2011: Menno van Zelm; Julie Smet; Mirjam van der Burg; Alina Ferster; Phu Quoc Le; Liliane Schandené; Jacques J M van Dongen; Françoise Mascart
Antibody deficiency due to a missense mutation in CD19 demonstrates the importance of the conserved tryptophan 41 in immunoglobulin superfamily domain formation.
Human molecular genetics 2011;20(9):1854-63.
2011: Tomasz Szczepanski; V H J van der Velden; Esmé Waanders; Roland P Kuiper; Pieter Van Vlierberghe; Bernd Gruhn; Cornelia Eckert; Renate Panzer-Grümayer; Giuseppe Basso; Hélène Cavé; Udo Zur Stadt; Dario Campana; André Schrauder; Rosemary Sutton; Elisabeth R van Wering; Jules P P Meijerink; Jacques J M van Dongen
Late recurrence of childhood T-cell acute lymphoblastic leukemia frequently represents a second leukemia rather than a relapse: first evidence for genetic predisposition.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(12):1643-9.
2011: Menno van Zelm; Anton W Langerak; Mirjam van der Burg; Jacques J M van Dongen
PID comes full circle: applications of V(D)J recombination excision circles in research, diagnostics and newborn screening of primary immunodeficiency disorders.
Frontiers in immunology 2011;2():12.
2011: Mirjam van der Burg; Menno van Zelm; Gertjan J A Driessen; Jacques J M van Dongen
Dissection of B-cell development to unravel defects in patients with a primary antibody deficiency.
Advances in experimental medicine and biology 2011;697():183-96.
2010: Jeltje F de Vries; Jeroen te Marvelde; Henk K Wind; Jacques J M van Dongen; V H J van der Velden
The potential use of basigin (CD147) as a prognostic marker in B-cell precursor acute lymphoblastic leukaemia.
British journal of haematology 2010;150(5):624-6.
2010: Tiago C Luis; Brigitta A E Naber; Willem E Fibbe; Jacques J M van Dongen; Frank Staal
Wnt3a nonredundantly controls hematopoietic stem cell function and its deficiency results in complete absence of canonical Wnt signaling.
Blood 2010;116(3):496-7.
2010: Mirjam van der Burg; Malgorzata Pac; Magdalena A Berkowska; Bozenna Goryluk-Kozakiewicz; Anna Wakulinska; Bozenna Dembowska-Baginska; Hanna Gregorek; Barbara H Barendregt; Malgorzata Krajewska-Walasek; Ewa Bernatowska; Jacques J M van Dongen; Krystyna H Chrzanowska; Anton Langerak
Loss of juxtaposition of RAG-induced immunoglobulin DNA ends is implicated in the precursor B-cell differentiation defect in NBS patients.
Blood 2010;115(23):4770-7.
2010: Wouter W Wiegant; Matty Meyers; Nicole S Verkaik; Mirjam van der Burg; Firouz Darroudi; Ron J Romeijn; Ewa Bernatowska; Beata Wolska-Kusnierz; Bozena Mikoluc; Nicolaas G J Jaspers; Cees Vreeken; Hanna Ijspeert; Rebecca E E Esveldt-van Lange; Anna Friedl; Jean-Pierre De Villartay; Leon H F Mullenders; Jacques J M van Dongen; Dik C van Gent; Albert Pastink; Malgorzata Z Zdzienicka
A novel radiosensitive SCID patient with a pronounced G(2)/M sensitivity.
DNA repair 2010;9(4):365-73.
2010: Menno van Zelm; Julie Smet; Brigitte Adams; Françoise Mascart; Liliane Schandené; Françoise Janssen; Alina Ferster; Chiung-Chi Kuo; Shoshana Levy; Jacques J M van Dongen; Mirjam van der Burg
CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency.
The Journal of clinical investigation 2010;120(4):1265-74.
2010: Elaine Costa; Rodrigo Tosta Peres; Julia Almeida; Quentin Lécrevisse; María Elena Arroyo; Cristina Teodósio; Carlos Eduardo Pedreira; Jacques J M van Dongen; Alberto Orfao
Harmonization of light scatter and fluorescence flow cytometry profiles obtained after staining peripheral blood leucocytes for cell surface-only versus intracellular antigens with the Fix & Perm reagent.
Cytometry. Part B, Clinical cytometry 2010;78(1):11-20.
2009: Tiago C Luis; Floor Weerkamp; Brigitta A E Naber; Miranda Baert; Edwin F E de Haas; Tatjana Nikolic; Sjanneke Heuvelmans; Ronald R de Krijger; Jacques J M van Dongen; Frank Staal
Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation.
Blood 2009;113(3):546-54.
2009: Mirjam van der Burg; Menno van Zelm; Jacques J M van Dongen
Molecular diagnostics of primary immunodeficiencies: benefits and future challenges.
Advances in experimental medicine and biology 2009;634():231-41.
2009: V H J van der Velden; Jacques J M van Dongen
MRD detection in acute lymphoblastic leukemia patients using Ig/TCR gene rearrangements as targets for real-time quantitative PCR.
Methods in molecular biology (Clifton, N.J.) 2009;538():115-50.
2009: Mirjam van der Burg; Hanna Ijspeert; Nicole S Verkaik; Tuba Turul; Wouter W Wiegant; Keiko Morotomi-Yano; Pierre-Olivier Mari; Ilhan Tezcan; David J Chen; Malgorzata Z Zdzienicka; Jacques J M van Dongen; Dik C van Gent
A DNA-PKcs mutation in a radiosensitive T-B- SCID patient inhibits Artemis activation and nonhomologous end-joining.
The Journal of clinical investigation 2009;119(1):91-8.
2009: Liesbeth Duijts; Liesbeth E Bakker-Jonges; Joost A M Labout; Vincent W V Jaddoe; Albert Hofman; Eric A P Steegers; Jacques J M van Dongen; Herbert Hooijkaas; Henriëtte A Moll
Fetal growth influences lymphocyte subset counts at birth: the Generation R Study.
Neonatology 2009;95(2):149-56.
2009: Tuba Turul; Ilhan Tezcan; Hasibe Artac; Sandra de Bruin-Versteeg; Barbara H Barendregt; Ismail Reisli; Ozden Sanal; Jacques J M van Dongen; Mirjam van der Burg
Clinical heterogeneity can hamper the diagnosis of patients with ZAP70 deficiency.
European journal of pediatrics 2009;168(1):87-93.
2009: Liesbeth Duijts; Liesbeth E Bakker-Jonges; Dennis O Mook-Kanamori; Joost A M Labout; Albert Hofman; C.M. Duijn; Jacques J M van Dongen; Herbert Hooijkaas; Henriëtte A Moll; Vincent W V Jaddoe
Variation in the IGF-1 gene is associated with lymphocyte subset counts in neonates: the Generation R Study.
Clinical endocrinology 2009;70(1):53-9.
2008: Frank Staal; Karin Pike-Overzet; Yuk Yin Ng; Jacques J M van Dongen
Sola dosis facit venenum. Leukemia in gene therapy trials: a question of vectors, inserts and dosage?
Leukemia 2008;22(10):1849-52.
2008: Patricia J T A Groenen; Anton W Langerak; Jacques J M van Dongen; Johan H J M van Krieken
Pitfalls in TCR gene clonality testing: teaching cases.
Journal of hematopathology 2008;1(2):97-109.
2008: Carlos E Pedreira; Elaine Costa; Susana Barrena; Quentin Lecrevisse; Julia Almeida; Jacques J M van Dongen; Alberto Orfao
Generation of flow cytometry data files with a potentially infinite number of dimensions.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2008;73(9):834-46.
2008: Suchit Jhunjhunwala; Menno van Zelm; Mandy M Peak; Steve Cutchin; Roy Riblet; Jacques J M van Dongen; Frank G Grosveld; Tobias A Knoch; Cornelis Murre
The 3D structure of the immunoglobulin heavy-chain locus: implications for long-range genomic interactions.
Cell 2008;133(2):265-79.
2008: Liesbeth Duijts; Liesbeth E Bakker-Jonges; Joost A M Labout; Vincent W V Jaddoe; Albert Hofman; Eric A P Steegers; Jacques J M van Dongen; Herbert Hooijkaas; Henriëtte A Moll
Perinatal stress influences lymphocyte subset counts in neonates. The generation R study.
Pediatric research 2008;63(3):292-8.
2008: Menno van Zelm; Corinne Geertsema; Nicole Nieuwenhuis; Dick de Ridder; Mary Ellen Conley; Claudine Schiff; Ilhan Tezcan; Ewa Bernatowska; Nico G Hartwig; Elisabeth A M Sanders; Jiri Litzman; Irina Kondratenko; Jacques J M van Dongen; Mirjam van der Burg
Gross deletions involving IGHM, BTK, or Artemis: a model for genomic lesions mediated by transposable elements.
American journal of human genetics 2008;82(2):320-32.
2007: Menno van Zelm; Mirjam van der Burg; Jacques J M van Dongen
Homeostatic and maturation-associated proliferation in the peripheral B-cell compartment.
Cell cycle (Georgetown, Tex.) 2007;6(23):2890-5.
2007: Karin Pike-Overzet; Mirjam van der Burg; Gerard Wagemaker; Jacques J M van Dongen; Frank Staal
New insights and unresolved issues regarding insertional mutagenesis in X-linked SCID gene therapy.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(11):1910-6.
2007: David González; Mirjam van der Burg; Ramón García-Sanz; James A Fenton; Anton Langerak; Marcos González; Jacques J M van Dongen; Jesús F San Miguel; Gareth J Morgan
Immunoglobulin gene rearrangements and the pathogenesis of multiple myeloma.
Blood 2007;110(9):3112-21.
2007: Jeroen G Noordzij; Nico G Hartwig; Frank A W Verreck; Sandra de Bruin-Versteeg; Tjitske de Boer; Jaap T van Dissel; Ronald de Groot; Tom H M Ottenhoff; Jacques J M van Dongen
Two patients with complete defects in interferon gamma receptor-dependent signaling.
Journal of clinical immunology 2007;27(5):490-6.
2007: Frank Staal; Jacques J M van Dongen; Anton W Langerak
Novel insights into the development of T-cell acute lymphoblastic leukemia.
Current hematologic malignancy reports 2007;2(3):176-82.
2007: Michaël Boudewijns; Jacques J M van Dongen; Anton Langerak
The human androgen receptor X-chromosome inactivation assay for clonality diagnostics of natural killer cell proliferations.
The Journal of molecular diagnostics : JMD 2007;9(3):337-44.
2007: Jan Zuna; Hélène Cavé; Cornelia Eckert; Tomasz Szczepanski; Claus Meyer; Ester Mejstrikova; Eva Fronkova; Katerina Muzikova; E Clappier; D Mendelova; Patrick Boutard; André Schrauder; J Sterba; Rolf Marschalek; Jacques J M van Dongen; Ondrej Hrusak; Jan Stary; Jan Trka
Childhood secondary ALL after ALL treatment.
Leukemia 2007;21(7):1431-5.
2007: Willem A Dik; Bertrand Nadel; Grzegorz K Przybylski; Vahid Asnafi; Piotr Grabarczyk; Jean-Marc Navarro; Brenda Verhaaf; Christian A Schmidt; Elizabeth Macintyre; Jacques J M van Dongen; Anton Langerak
Different chromosomal breakpoints impact the level of LMO2 expression in T-ALL.
Blood 2007;110(1):388-92.
2007: Roland B Walter; Theodore A Gooley; V H J van der Velden; Michael R Loken; Jacques J M van Dongen; David A Flowers; Irwin D Bernstein; Frederick R Appelbaum
CD33 expression and P-glycoprotein-mediated drug efflux inversely correlate and predict clinical outcome in patients with acute myeloid leukemia treated with gemtuzumab ozogamicin monotherapy.
Blood 2007;109(10):4168-70.
2007: V H J van der Velden; E Renate Panzer-Grümayer; Giovanni Cazzaniga; T Flohr; R Sutton; André Schrauder; G Basso; Martin Schrappe; JM Wijkhuijs; M Konrad; C R Bartram; Guiseppe Masera; A Biondi; Jacques J M van Dongen
Optimization of PCR-based minimal residual disease diagnostics for childhood acute lymphoblastic leukemia in a multi-center setting.
Leukemia 2007;21(4):706-13.
2007: V H J van der Velden; Giovanni Cazzaniga; André Schrauder; J Hancock; Peter Bader; E R Panzer-Grumayer; T Flohr; R Sutton; H Cave; H O Madsen; Jean-Michel Cayuela; Jan Trka; Cornelia Eckert; Letizia Foroni; Udo zur Stadt; Kheira Beldjord; Thorsten Raff; C. Ellen van der Schoot; Jacques J M van Dongen
Analysis of minimal residual disease by Ig/TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data.
Leukemia 2007;21(4):604-11.
2007: Karin Pike-Overzet; Dick de Ridder; Floor Weerkamp; Miranda Baert; M M A Verstegen; Martijn Brugman; Steven J Howe; Marcel J T Reinders; Adrian J Thrasher; Gerard Wagemaker; Jacques J M van Dongen; Frank Staal
Ectopic retroviral expression of LMO2, but not IL2Rgamma, blocks human T-cell development from CD34+ cells: implications for leukemogenesis in gene therapy.
Leukemia 2007;21(4):754-63.
2007: M W J C Jansen; L Corral; V H J van der Velden; R Panzer-Grümayer; Martin Schrappe; André Schrauder; Rolf Marschalek; Claus Meyer; Monique L den Boer; W J C Hop; Maria Grazia Valsecchi; G Basso; A Biondi; Rob Pieters; Jacques J M van Dongen
Immunobiological diversity in infant acute lymphoblastic leukemia is related to the occurrence and type of MLL gene rearrangement.
Leukemia 2007;21(4):633-41.
2007: Menno van Zelm; Tomasz Szczepanski; Mirjam van der Burg; Jacques J M van Dongen
Replication history of B lymphocytes reveals homeostatic proliferation and extensive antigen-induced B cell expansion.
The Journal of experimental medicine 2007;204(3):645-55.
2007: Firouz Darroudi; Wouter W Wiegant; Matty Meijers; Anna Friedl; Mirjam van der Burg; Janna Fomina; Jacques J M van Dongen; Dik C van Gent; Malgorzata Z Zdzienicka
Role of Artemis in DSB repair and guarding chromosomal stability following exposure to ionizing radiation at different stages of cell cycle.
Mutation research 2007;615(1-2):111-24.
2007: Monika Brüggemann; H White; P Gaulard; R Garcia-Sanz; Paula Gameiro; S Oeschger; B Jasani; M Ott; G Delsol; A Orfao; Markus Tiemann; Hermann Herbst; Anton Langerak; M Spaargaren; E Moreau; Patricia J T A Groenen; C Sambade; Letizia Foroni; G I Carter; M Hummel; Christian Bastard; Frédéric Davi; M-H Delfau-Larue; Michael Kneba; Jacques J M van Dongen; Kheira Beldjord; TJ Molina
Powerful strategy for polymerase chain reaction-based clonality assessment in T-cell malignancies Report of the BIOMED-2 Concerted Action BHM4 CT98-3936.
Leukemia 2007;21(2):215-21.
2007: Anton Langerak; TJ Molina; Frances L Lavender; D Pearson; T Flohr; C Sambade; E Schuuring; T Al Saati; Jacques J M van Dongen; J H J M van Krieken
Polymerase chain reaction-based clonality testing in tissue samples with reactive lymphoproliferations: usefulness and pitfalls. A report of the BIOMED-2 Concerted Action BMH4-CT98-3936.
Leukemia 2007;21(2):222-9.
2007: Yorick Sandberg; Brenda Verhaaf; Ellen J van Gastel-Mol; Ingrid L M Wolvers-Tettero; J de Vos; Roderick MacLeod; Jeroen G Noordzij; Willem A Dik; Jacques J M van Dongen; Anton Langerak
Human T-cell lines with well-defined T-cell receptor gene rearrangements as controls for the BIOMED-2 multiplex polymerase chain reaction tubes.
Leukemia 2007;21(2):230-7.
2006: Mirjam van der Burg; Corry M R Weemaes; Frank W M B Preijers; Paul Brons; Barbara H Barendregt; Maarten J D van Tol; Peter Hoogerbrugge; Jacques J M van Dongen
B-cell recovery after stem cell transplantation of Artemis-deficient SCID requires elimination of autologous bone marrow precursor-B-cells.
Haematologica 2006;91(12):1705-9.
2006: Yorick Sandberg; V O Dezentjé; Karoly Szuhai; A J van Houte; Dennis Tielemans; Ingrid L M Wolvers-Tettero; Jacques J M van Dongen; R van der Griend; Anton Langerak
Clonal T- and natural killer-cell large granular lymphocyte proliferations in a single patient established by array-based comparative genomic hybridization analysis.
Leukemia 2006;20(12):2212-4.
2006: Floor Weerkamp; Tiago C Luis; Brigitta A E Naber; Esther E L Koster; L Jeannotte; Jacques J M van Dongen; Frank Staal
Identification of Notch target genes in uncommitted T-cell progenitors: No direct induction of a T-cell specific gene program.
Leukemia 2006;20(11):1967-77.
2006: Karin Pike-Overzet; Dick de Ridder; Floor Weerkamp; Miranda Baert; Monique M Verstegen; Martijn Brugman; Steven J Howe; Marcel J T Reinders; Adrian J Thrasher; Gerard Wagemaker; Jacques J M van Dongen; Frank Staal
Gene therapy: is IL2RG oncogenic in T-cell development?
Nature 2006;443(7109):E5; discussion E6-7.
2006: Frank Staal; Gunnar Cario; Giovanni Cazzaniga; T Haferlach; Michael Heuser; W-K Hofmann; K Mills; Martin Schrappe; Martin Stanulla; Luzie U Wingen; Jacques J M van Dongen; Brigitte Schlegelberger
Consensus guidelines for microarray gene expression analyses in leukemia from three European leukemia networks.
Leukemia 2006;20(8):1385-92.
2006: Floor Weerkamp; Jacques J M van Dongen; Frank Staal
Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia.
Leukemia 2006;20(7):1197-205.
2006: Menno van Zelm; Ismail Reisli; Mirjam van der Burg; Diana Castaño; Carel J M van Noesel; Maarten J D van Tol; Cristina Woellner; Bodo Grimbacher; Pablo Patino; Jacques J M van Dongen; José L Franco
An antibody-deficiency syndrome due to mutations in the CD19 gene.
The New England journal of medicine 2006;354(18):1901-12.
2006: V H J van der Velden; Patricia G Hoogeveen; Rob Pieters; Jacques J M van Dongen
Impact of two independent bone marrow samples on minimal residual disease monitoring in childhood acute lymphoblastic leukaemia.
British journal of haematology 2006;133(4):382-8.
2006: V H J van der Velden; Maaike de Bie; Elisabeth R van Wering; Jacques J M van Dongen
Immunoglobulin light chain gene rearrangements in precursor-B-acute lymphoblastic leukemia: characteristics and applicability for the detection of minimal residual disease.
Haematologica 2006;91(5):679-82.
2006: Hélia Neves; Floor Weerkamp; Andreia C Gomes; Brigitta A E Naber; Paula Gameiro; Jorg Becker; Paulo Lucio; Nuno Clode; Jacques J M van Dongen; Frank Staal; Leonor Parreira
Effects of Delta1 and Jagged1 on early human hematopoiesis: correlation with expression of notch signaling-related genes in CD34+ cells.
Stem cells (Dayton, Ohio) 2006;24(5):1328-37.
2006: Klaus Warnatz; Lukas Bossaller; Ulrich Salzer; Andrea Skrabl-Baumgartner; Wolfgang Schwinger; Mirjam van der Burg; Jacques J M van Dongen; Marzena Orlowska-Volk; Rolf Knoth; Anne Durandy; Ruth Draeger; Michael Schlesier; Hans-Hartmut Peter; Bodo Grimbacher
Human ICOS deficiency abrogates the germinal center reaction and provides a monogenic model for common variable immunodeficiency.
Blood 2006;107(8):3045-52.
2006: Floor Weerkamp; Miranda Baert; Martijn Brugman; Willem A Dik; Edwin F E de Haas; Trudi P Visser; Christianne J M De Groot; Gerard Wagemaker; Jacques J M van Dongen; Frank Staal
Human thymus contains multipotent progenitors with T/B lymphoid, myeloid, and erythroid lineage potential.
Blood 2006;107(8):3131-7.
2006: Grzegorz K Przybylski; Willem A Dik; Piotr Grabarczyk; Jens Wanzeck; Paulina Chudobska; Kacper Jankowski; Anne von Bergh; Jacques J M van Dongen; Christian A Schmidt; Anton Langerak
The effect of a novel recombination between the homeobox gene NKX2-5 and the TRD locus in T-cell acute lymphoblastic leukemia on activation of the NKX2-5 gene.
Haematologica 2006;91(3):317-21.
2006: Yorick Sandberg; Julia Almeida; M Gonzalez; Margarida Lima; Paloma Bárcena; T Szczepañski; Ellen J van Gastel-Mol; Henk Wind; Ana Balanzategui; Jacques J M van Dongen; J F San Miguel; Alberto Orfao; Anton Langerak
TCRgammadelta+ large granular lymphocyte leukemias reflect the spectrum of normal antigen-selected TCRgammadelta+ T-cells.
Leukemia 2006;20(3):505-13.
2006: Floor Weerkamp; Miranda Baert; Brigitta A E Naber; Esther E L Koster; Edwin F E de Haas; Kondala R Atkuri; Jacques J M van Dongen; Leonore A Herzenberg; Frank Staal
Wnt signaling in the thymus is regulated by differential expression of intracellular signaling molecules.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(9):3322-6.
2006: Dick de Ridder; Frank Staal; Jacques J M van Dongen; Marcel J T Reinders
Maximum significance clustering of oligonucleotide microarrays.
Bioinformatics (Oxford, England) 2006;22(3):326-31.
2006: Tomasz Szczepański; V H J van der Velden; Jacques J M van Dongen
Flow-cytometric immunophenotyping of normal and malignant lymphocytes.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2006;44(7):775-96.
2006: Anton Langerak; Jacques J M van Dongen
Recombination in the human IGK locus.
Critical reviews in immunology 2006;26(1):23-42.
2006: Mirjam van der Burg; Lieneke R van Veelen; Nicole S Verkaik; Wouter W Wiegant; Nico G Hartwig; Barbara H Barendregt; Linda Brugmans; Anja Raams; Nicolaas G J Jaspers; Malgorzata Z Zdzienicka; Jacques J M van Dongen; Dik C van Gent
A new type of radiosensitive T-B-NK+ severe combined immunodeficiency caused by a LIG4 mutation.
The Journal of clinical investigation 2006;116(1):137-45.
2006: Yang Yang; Seisho Takeuchi; Wolf-Karsten Hofmann; Takayuki Ikezoe; Jacques J M van Dongen; Tomasz Szczepański; Claus R Bartram; Norihide Yoshino; Hirokuni Taguchi; H Phillip Koeffler
Aberrant methylation in promoter-associated CpG islands of multiple genes in acute lymphoblastic leukemia.
Leukemia research 2006;30(1):98-102.
2005: E Renate Panzer-Grümayer; Giovanni Cazzaniga; V H J van der Velden; Laura del Giudice; Martina Peham; Georg Mann; Cornelia Eckert; André Schrauder; Giuseppe Germano; Jochen Harbott; Giuseppe Basso; Andrea Biondi; Jacques J M van Dongen; Helmut Gadner; Oskar A Haas
Immunogenotype changes prevail in relapses of young children with TEL-AML1-positive acute lymphoblastic leukemia and derive mainly from clonal selection.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(21):7720-7.
2005: Menno van Zelm; Mirjam van der Burg; Dick de Ridder; Barbara H Barendregt; Edwin F E de Haas; Marcel J T Reinders; Arjan C Lankester; Tom Révész; Frank Staal; Jacques J M van Dongen
Ig gene rearrangement steps are initiated in early human precursor B cell subsets and correlate with specific transcription factor expression.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(9):5912-22.
2005: Nancy Boeckx; J De Roover; V H J van der Velden; J Maertens; Anne Uyttebroeck; Peter Vandenberghe; Jacques J M van Dongen
Quantification of CBFB-MYH11 fusion gene levels in paired peripheral blood and bone marrow samples by real-time PCR.
Leukemia 2005;19(11):1988-90.
2005: M W J C Jansen; V H J van der Velden; Jacques J M van Dongen
Efficient and easy detection of MLL-AF4, MLL-AF9 and MLL-ENL fusion gene transcripts by multiplex real-time quantitative RT-PCR in TaqMan and LightCycler.
Leukemia 2005;19(11):2016-8.
2005: Willem A Dik; Wajih Brahim; C Braun; Vahid Asnafi; Nicole Dastugue; Olivier A Bernard; Jacques J M van Dongen; Anton Langerak; Elizabeth Macintyre; Eric Delabesse
CALM-AF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes.
Leukemia 2005;19(11):1948-57.
2005: Yorick Sandberg; Ellen J van Gastel-Mol; Brenda Verhaaf; King H Lam; Jacques J M van Dongen; Anton Langerak
BIOMED-2 multiplex immunoglobulin/T-cell receptor polymerase chain reaction protocols can reliably replace Southern blot analysis in routine clonality diagnostics.
The Journal of molecular diagnostics : JMD 2005;7(4):495-503.
2005: Richard A Larson; Eric L Sievers; Edward A Stadtmauer; Bob Löwenberg; Elihu H Estey; Hervé Dombret; Matthias Theobald; Dimitris Voliotis; John M Bennett; Maria Richie; Lance H Leopold; Mark S Berger; Matthew L Sherman; Michael R Loken; Jacques J M van Dongen; Irwin D Bernstein; Frederick R Appelbaum
Final report of the efficacy and safety of gemtuzumab ozogamicin (Mylotarg) in patients with CD33-positive acute myeloid leukemia in first recurrence.
Cancer 2005;104(7):1442-52.
2005: Nancy Boeckx; M W J C Jansen; C Haskovec; Peter Vandenberghe; V H J van der Velden; Jacques J M van Dongen
Identification of e19a2 BCR-ABL fusions (mu-BCR breakpoints) at the DNA level by ligation-mediated PCR.
Leukemia 2005;19(7):1292-5.
2005: Willem A Dik; Karin Pike-Overzet; Floor Weerkamp; Dick de Ridder; Edwin F E de Haas; Miranda Baert; Peter van der Spek; Esther E L Koster; Marcel J T Reinders; Jacques J M van Dongen; Anton Langerak; Frank Staal
New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling.
The Journal of experimental medicine 2005;201(11):1715-23.
2005: Floor Weerkamp; Edwin F E de Haas; Brigitta A E Naber; W Marieke Comans-Bitter; Ad J J C Bogers; Jacques J M van Dongen; Frank Staal
Age-related changes in the cellular composition of the thymus in children.
The Journal of allergy and clinical immunology 2005;115(4):834-40.
2005: Dick de Ridder; C E van der Linden; T Schonewille; Willem A Dik; Marcel J T Reinders; Jacques J M van Dongen; Frank Staal
Purity for clarity: the need for purification of tumor cells in DNA microarray studies.
Leukemia 2005;19(4):618-27.
2005: Grzegorz K Przybylski; Willem A Dik; Jens Wanzeck; Piotr Grabarczyk; S Majunke; J I Martin-Subero; R Siebert; Gottfried Dölken; W-D Ludwig; Brenda Verhaaf; Jacques J M van Dongen; Christian A Schmidt; Anton Langerak
Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL.
Leukemia 2005;19(2):201-8.
2005: Claus Meyer; Bjoern Schneider; Martin Reichel; Sieglinde Angermueller; Sabine Strehl; Susanne Schnittger; Claudia Schoch; M W J C Jansen; Jacques J M van Dongen; Rob Pieters; Oskar A Haas; Theo Dingermann; Thomas Klingebiel; Rolf Marschalek
Diagnostic tool for the identification of MLL rearrangements including unknown partner genes.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(2):449-54.
2005: Jacques J M van Dongen; M van der Burg; Anton Langerak
Split-signal FISH for detection of chromosome aberrations.
Hematology (Amsterdam, Netherlands) 2005;10 Suppl 1():66-72.
2004: V H J van der Velden; Monika Brüggemann; Patricia G Hoogeveen; Maaike de Bie; P G Hart; Thorsten Raff; Heike Pfeifer; Silke Lüschen; T Szczepański; Elisabeth R van Wering; Michael Kneba; Jacques J M van Dongen
TCRB gene rearrangements in childhood and adult precursor-B-ALL: frequency, applicability as MRD-PCR target, and stability between diagnosis and relapse.
Leukemia 2004;18(12):1971-80.
2004: Anton Langerak; Bertrand Nadel; Anneke de Torbal; Ingrid L M Wolvers-Tettero; Ellen J van Gastel-Mol; Brenda Verhaaf; Ulrich Jäger; Jacques J M van Dongen
Unraveling the consecutive recombination events in the human IGK locus.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(6):3878-88.
2004: Birgit Levelink; Esther de Vries; Jaap T van Dissel; Jacques J M van Dongen
Pulmonary mycobacterium avium intracellulare infection in an immunocompetent child.
The Pediatric infectious disease journal 2004;23(9):892.
2004: Jo Droese; Anton Langerak; Patricia J T A Groenen; Monika Brüggemann; P Neumann; Ingrid L M Wolvers-Tettero; M C van Altena; Michael Kneba; Jacques J M van Dongen
Validation of BIOMED-2 multiplex PCR tubes for detection of TCRB gene rearrangements in T-cell malignancies.
Leukemia 2004;18(9):1531-8.
2004: Nancy Boeckx; V H J van der Velden; Marc Boogaerts; Anne Hagemeijer; Peter Vandenberghe; Jacques J M van Dongen
An inv(16)(p13q22) positive acute myeloid leukaemia relapsing as acute precursor B-cell lymphoblastic leukaemia.
Haematologica 2004;89(8):ECR28.
2004: Ellen G van Lochem; V H J van der Velden; Henk Wind; Jeroen te Marvelde; N A C Westerdaal; Jacques J M van Dongen
Immunophenotypic differentiation patterns of normal hematopoiesis in human bone marrow: reference patterns for age-related changes and disease-induced shifts.
Cytometry. Part B, Clinical cytometry 2004;60(1):1-13.
2004: Chise Matsushita; Yang Yang; Seisho Takeuchi; Masahide Matsushita; Jacques J M van Dongen; Tomasz Szczepanski; Claus R Bartram; Hiromi Seo; H Phillip Koeffler; Hirokuni Taguchi
Aberrant methylation in promoter-associated CpG islands of multiple genes in relapsed childhood acute lymphoblastic leukemia.
Oncology reports 2004;12(1):97-9.
2004: Laura J C M van Zutven; Sandra C J M Velthuizen; Ingrid L M Wolvers-Tettero; Jacques J M van Dongen; Tim S Poulsen; Roderick MacLeod; Berna Beverloo; Anton Langerak
Two dual-color split signal fluorescence in situ hybridization assays to detect t(5;14) involving HOX11L2 or CSX in T-cell acute lymphoblastic leukemia.
Haematologica 2004;89(6):671-8.
2004: A G S C Jansen; Jeroen G Noordzij; Annette H J T Bröcker-Vriends; Jacques J M van Dongen; Maarten J D van Tol; R G M Bredius
[Widely divergent clinical phenotype of x-linked agammaglobulinemia in two cousins].
Nederlands tijdschrift voor geneeskunde 2004;148(21):1053-6.
2004: Tomasz Szczepanski; V H J van der Velden; Patricia G Hoogeveen; Maaike de Bie; D C H Jacobs; Elisabeth R van Wering; Jacques J M van Dongen
Vdelta2-Jalpha rearrangements are frequent in precursor-B-acute lymphoblastic leukemia but rare in normal lymphoid cells.
Blood 2004;103(10):3798-804.
2004: Mirjam van der Burg; T S Poulsen; Stephen P Hunger; Berna Beverloo; Elisabeth M E Smit; Kirsten Vang Nielsen; Anton Langerak; Jacques J M van Dongen
Split-signal FISH for detection of chromosome aberrations in acute lymphoblastic leukemia.
Leukemia 2004;18(5):895-908.
2004: V H J van der Velden; Nancy Boeckx; Inge Jedema; Jeroen te Marvelde; Patricia G Hoogeveen; Marc Boogaerts; Jacques J M van Dongen
High CD33-antigen loads in peripheral blood limit the efficacy of gemtuzumab ozogamicin (Mylotarg) treatment in acute myeloid leukemia patients.
Leukemia 2004;18(5):983-8.
2004: V H J van der Velden; Nancy Boeckx; Elisabeth R van Wering; Jacques J M van Dongen
Detection of minimal residual disease in acute leukemia.
Journal of biological regulators and homeostatic agents 2004;18(2):146-54.
2004: Tomasz Szczepański; Gerard A M de Vaan; Auke Beishuizen; José Bogman; M W J C Jansen; Elisabeth R van Wering; Jacques J M van Dongen
Acute lymphoblastic leukemia followed by a clonally-unrelated EBV-positive non-Hodgkin lymphoma and a clonally-related myelomonocytic leukemia cutis.
Pediatric blood & cancer 2004;42(4):343-9.
2004: Monika Brüggemann; V H J van der Velden; Thorsten Raff; Jo Droese; Matthias Ritgen; Christiane Pott; A J M Wijkhuijs; Nicola Gökbuget; Dieter Hoelzer; Elisabeth R van Wering; Jacques J M van Dongen; Michael Kneba
Rearranged T-cell receptor beta genes represent powerful targets for quantification of minimal residual disease in childhood and adult T-cell acute lymphoblastic leukemia.
Leukemia 2004;18(4):709-19.
2004: V H J van der Velden; Nancy Boeckx; M Gonzalez; Maria Malec; G Barbany; Thomas Lion; Enrico Gottardi; N Pallisgaard; Emmanuel Beillard; W C J Hop; Patricia G Hoogeveen; Jean Gabert; Jacques J M van Dongen
Differential stability of control gene and fusion gene transcripts over time may hamper accurate quantification of minimal residual disease--a study within the Europe Against Cancer Program.
Leukemia 2004;18(4):884-6.
2004: Inge Jedema; Renée M Y Barge; V H J van der Velden; Bart A Nijmeijer; Jacques J M van Dongen; Rein Willemze; J H Frederik Falkenburg
Internalization and cell cycle-dependent killing of leukemic cells by Gemtuzumab Ozogamicin: rationale for efficacy in CD33-negative malignancies with endocytic capacity.
Leukemia 2004;18(2):316-25.
2004: Frank Staal; Floor Weerkamp; Miranda Baert; Caroline M M van den Burg; Mascha van Noort; Edwin F E de Haas; Jacques J M van Dongen
Wnt target genes identified by DNA microarrays in immature CD34+ thymocytes regulate proliferation and cell adhesion.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(2):1099-108.
2003: Jacques J M van Dongen; Anton Langerak; Monika Brüggemann; P A S Evans; M Hummel; Frances L Lavender; Eric Delabesse; Frédéric Davi; E Schuuring; R García-Sanz; J H J M van Krieken; Jo Droese; D González; Christian Bastard; H E White; M Spaargaren; M González; A Parreira; J L Smith; G J Morgan; Michael Kneba; Elizabeth Macintyre
Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936.
Leukemia 2003;17(12):2257-317.
2003: Tomasz Szczepański; V H J van der Velden; Jacques J M van Dongen
Classification systems for acute and chronic leukaemias.
Best practice & research. Clinical haematology 2003;16(4):561-82.
2003: Jean Gabert; Emmanuel Beillard; V H J van der Velden; W Bi; David Grimwade; N Pallisgaard; G Barbany; Giovanni Cazzaniga; Jean-Michel Cayuela; H Cavé; Fabrizio Pane; J L E Aerts; D De Micheli; Xavier Thirion; Vincent Pradel; M González; Susanne Viehmann; Maria Malec; Giuseppe Saglio; Jacques J M van Dongen
Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program.
Leukemia 2003;17(12):2318-57.
2003: Emmanuel Beillard; N Pallisgaard; V H J van der Velden; W Bi; R Dee; E van der Schoot; Eric Delabesse; Elizabeth Macintyre; Enrico Gottardi; Giuseppe Saglio; Franz Watzinger; Thomas Lion; Jacques J M van Dongen; Peter Hokland; Jean Gabert
Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time' quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR) - a Europe against cancer program.
Leukemia 2003;17(12):2474-86.
2003: Anton Langerak; Yorick Sandberg; Jacques J M van Dongen
Spectrum of T-large granular lymphocyte lymphoproliferations: ranging from expanded activated effector T cells to T-cell leukaemia.
British journal of haematology 2003;123(3):561-2.
2003: T Szczepański; V H J van der Velden; Thorsten Raff; D C H Jacobs; Elisabeth R van Wering; Monika Brüggemann; Michael Kneba; Jacques J M van Dongen
Comparative analysis of T-cell receptor gene rearrangements at diagnosis and relapse of T-cell acute lymphoblastic leukemia (T-ALL) shows high stability of clonal markers for monitoring of minimal residual disease and reveals the occurrence of second T-ALL.
Leukemia 2003;17(11):2149-56.
2003: Seisho Takeuchi; Taku Seriu; Jacques J M van Dongen; Tomasz Szczepański; Kunihiro Tsukasaki; Naoko Takeuchi; Anthony C Fermin; Hiromi Seo; Claus R Bartram; H Phillip Koeffler
Allelotype analysis in relapsed childhood acute lymphoblastic leukemia.
Oncogene 2003;22(44):6970-6.
2003: O Krejci; V H J van der Velden; Peter Bader; Hermann Kreyenberg; Nicholas J Goulden; J Hancock; M W Schilham; Arjan C Lankester; Tom Révész; Thomas Klingebiel; Jacques J M van Dongen
Level of minimal residual disease prior to haematopoietic stem cell transplantation predicts prognosis in paediatric patients with acute lymphoblastic leukaemia: a report of the Pre-BMT MRD Study Group.
Bone marrow transplantation 2003;32(8):849-51.
2003: V H J van der Velden; Tomasz Szczepanski; JM Wijkhuijs; P G Hart; Patricia G Hoogeveen; W C J Hop; Elisabeth R van Wering; Jacques J M van Dongen
Age-related patterns of immunoglobulin and T-cell receptor gene rearrangements in precursor-B-ALL: implications for detection of minimal residual disease.
Leukemia 2003;17(9):1834-44.
2003: Frank Staal; Mirjam van der Burg; Lodewyk F A Wessels; Barbara H Barendregt; Miranda Baert; Caroline M M van den Burg; Christophe Henri Van Huffel; Anton Langerak; V H J van der Velden; Marcel J T Reinders; Jacques J M van Dongen
DNA microarrays for comparison of gene expression profiles between diagnosis and relapse in precursor-B acute lymphoblastic leukemia: choice of technique and purification influence the identification of potential diagnostic markers.
Leukemia 2003;17(7):1324-32.
2003: Yorick Sandberg; Freerk Heule; King Lam; Pieternella J Lugtenburg; Ingrid L M Wolvers-Tettero; Jacques J M van Dongen; Anton Langerak
Molecular immunoglobulin/T- cell receptor clonality analysis in cutaneous lymphoproliferations. Experience with the BIOMED-2 standardized polymerase chain reaction protocol.
Haematologica 2003;88(6):659-70.
2003: V H J van der Velden; A Hochhaus; Giovanni Cazzaniga; Tomasz Szczepanski; Jean Gabert; Jacques J M van Dongen
Detection of minimal residual disease in hematologic malignancies by real-time quantitative PCR: principles, approaches, and laboratory aspects.
Leukemia 2003;17(6):1013-34.
2003: J H J M van Krieken; Anton Langerak; J F San Miguel; A Parreira; J L Smith; G M Morgan; Michael Kneba; Elizabeth Macintyre; Jacques J M van Dongen
Clonality analysis for antigen receptor genes: preliminary results from the Biomed-2 concerted action PL 96-3936.
Human pathology 2003;34(4):359-61.
2003: Jeroen G Noordzij; Nicole S Verkaik; Mirjam van der Burg; Lieneke R van Veelen; Sandra de Bruin-Versteeg; Wouter W Wiegant; Jaak M Vossen; Corry M R Weemaes; Ronald de Groot; Malgorzata Z Zdzienicka; Dik C van Gent; Jacques J M van Dongen
Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre-B-cell receptor checkpoint in bone marrow.
Blood 2003;101(4):1446-52.
2003: John Moppett; V H J van der Velden; A J M Wijkhuijs; J Hancock; Jacques J M van Dongen; Nicholas J Goulden
Inhibition affecting RQ-PCR-based assessment of minimal residual disease in acute lymphoblastic leukemia: reversal by addition of bovine serum albumin.
Leukemia 2003;17(1):268-70.
2003: Grzegorz K Przybylski; Jens Wanzeck; Martie C M Verschuren; Jacques J M van Dongen; Stephan Serke; Christian A Schmidt
Identification of a new cluster of T-cell receptor delta recombining elements.
Immunology 2003;108(1):16-23.
2002: Jeroen G Noordzij; Sandra de Bruin-Versteeg; Nicole S Verkaik; Jaak M Vossen; Ronald de Groot; Ewa Bernatowska; Anton Langerak; Dik C van Gent; Jacques J M van Dongen
The immunophenotypic and immunogenotypic B-cell differentiation arrest in bone marrow of RAG-deficient SCID patients corresponds to residual recombination activities of mutated RAG proteins.
Blood 2002;100(6):2145-52.
2002: Jeroen G Noordzij; Sandra de Bruin-Versteeg; Nico G Hartwig; Corry M R Weemaes; Egbert J A Gerritsen; Ewa Bernatowska; Stefaan van Lierde; Ronald de Groot; Jacques J M van Dongen
XLA patients with BTK splice-site mutations produce low levels of wild-type BTK transcripts.
Journal of clinical immunology 2002;22(5):306-18.
2002: Richard A Larson; M Boogaerts; E Estey; Chatchada Karanes; Edward A Stadtmauer; Eric L Sievers; P Mineur; John M Bennett; Mark S Berger; Catharine B Eten; M Munteanu; Michael R Loken; Jacques J M van Dongen; Irwin D Bernstein; Frederick R Appelbaum
Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin).
Leukemia 2002;16(9):1627-36.
2002: Anton Langerak; E Moreau; Ellen J van Gastel-Mol; Mirjam van der Burg; Jacques J M van Dongen
Detection of clonal EBV episomes in lymphoproliferations as a diagnostic tool.
Leukemia 2002;16(8):1572-3.
2002: Mirjam van der Burg; Barbara H Barendregt; T Szczepañski; Elisabeth R van Wering; Anton Langerak; Jacques J M van Dongen
Immunoglobulin light chain gene rearrangements display hierarchy in absence of selection for functionality in precursor-B-ALL.
Leukemia 2002;16(8):1448-53.
2002: V H J van der Velden; D C H Jacobs; A J M Wijkhuijs; W Marieke Comans-Bitter; Marja J Willemse; Karel Hählen; Willem A Kamps; Elisabeth R van Wering; Jacques J M van Dongen
Minimal residual disease levels in bone marrow and peripheral blood are comparable in children with T cell acute lymphoblastic leukemia (ALL), but not in precursor-B-ALL.
Leukemia 2002;16(8):1432-6.
2002: Annoek E C Broers; Jules P P Meijerink; Jacques J M van Dongen; Sandra J Posthumus; Bob Löwenberg; Eric Braakman; Jan J Cornelissen
Quantification of newly developed T cells in mice by real-time quantitative PCR of T-cell receptor rearrangement excision circles.
Experimental hematology 2002;30(7):745-50.
2002: V H J van der Velden; JM Wijkhuijs; D C H Jacobs; Elisabeth R van Wering; Jacques J M van Dongen
T cell receptor gamma gene rearrangements as targets for detection of minimal residual disease in acute lymphoblastic leukemia by real-time quantitative PCR analysis.
Leukemia 2002;16(7):1372-80.
2002: Mirjam van der Burg; Richard Bende; Wilhelmina M Aarts; Anton Langerak; Jacques J M van Dongen; Carel J M van Noesel
Biased Iglambda expression in hypermutated IgD multiple myelomas does not result from receptor revision.
Leukemia 2002;16(7):1358-61.
2002: Mirjam van der Burg; Barbara H Barendregt; Ellen J van Gastel-Mol; Talip Tümkaya; Anton Langerak; Jacques J M van Dongen
Unraveling of the polymorphic C lambda 2-C lambda 3 amplification and the Ke+Oz- polymorphism in the human Ig lambda locus.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(1):271-6.
2002: Marja J Willemse; Taku Seriu; Klaudia Hettinger; Elisabetta d'Aniello; Wim C J Hop; E Renate Panzer-Grümayer; Andrea Biondi; Martin Schrappe; Willem A Kamps; Guiseppe Masera; Helmut Gadner; Hansjörg Riehm; Claus R Bartram; Jacques J M van Dongen
Detection of minimal residual disease identifies differences in treatment response between T-ALL and precursor B-ALL.
Blood 2002;99(12):4386-93.
2002: V H J van der Velden; Marja J Willemse; C Ellen van der Schoot; Karel Hählen; Elisabeth R van Wering; Jacques J M van Dongen
Immunoglobulin kappa deleting element rearrangements in precursor-B acute lymphoblastic leukemia are stable targets for detection of minimal residual disease by real-time quantitative PCR.
Leukemia 2002;16(5):928-36.
2002: Mirjam van der Burg; B Smit; Bas Brinkhof; Barbara H Barendregt; M C M Verschuren; M Dib; Berna Beverloo; Jacques J M van Dongen; Anton Langerak
A single split-signal FISH probe set allows detection of TAL1 translocations as well as SIL-TAL1 fusion genes in a single test.
Leukemia 2002;16(4):755-61.
2002: Tomasz Szczepański; Marja J Willemse; Bas Brinkhof; Elisabeth R van Wering; Mirjam van der Burg; Jacques J M van Dongen
Comparative analysis of Ig and TCR gene rearrangements at diagnosis and at relapse of childhood precursor-B-ALL provides improved strategies for selection of stable PCR targets for monitoring of minimal residual disease.
Blood 2002;99(7):2315-23.
2002: Tomasz Szczepański; Thomas Flohr; V H J van der Velden; Claus R Bartram; Jacques J M van Dongen
Molecular monitoring of residual disease using antigen receptor genes in childhood acute lymphoblastic leukaemia.
Best practice & research. Clinical haematology 2002;15(1):37-57.
2002: Nancy Boeckx; Marja J Willemse; Tomasz Szczepanski; V H J van der Velden; Anton Langerak; P Vandekerckhove; Jacques J M van Dongen
Fusion gene transcripts and Ig/TCR gene rearrangements are complementary but infrequent targets for PCR-based detection of minimal residual disease in acute myeloid leukemia.
Leukemia 2002;16(3):368-75.
2002: Jeroen G Noordzij; Sandra de Bruin-Versteeg; W Marieke Comans-Bitter; Nico G Hartwig; Rudolf W Hendriks; Ronald de Groot; Jacques J M van Dongen
Composition of precursor B-cell compartment in bone marrow from patients with X-linked agammaglobulinemia compared with healthy children.
Pediatric research 2002;51(2):159-68.
2002: Dieter Hoelzer; Nicola Gökbuget; Oliver G Ottmann; Ching-Hon Pui; Mary Relling; Frederick R Appelbaum; Jacques J M van Dongen; Tomasz Szczepański
Acute lymphoblastic leukemia.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2002;():162-92.
2002: V de Haas; Willemijn B Breunis; R Dee; Onno J H M Verhagen; Wilma G M Kroes; Elisabeth R van Wering; Jacques J M van Dongen; H van den Berg; C Ellen van der Schoot
The TEL-AML1 real-time quantitative polymerase chain reaction (PCR) might replace the antigen receptor-based genomic PCR in clinical minimal residual disease studies in children with acute lymphoblastic leukaemia.
British journal of haematology 2002;116(1):87-93.
2001: K Aleman; Jeroen G Noordzij; Ronald de Groot; Jacques J M van Dongen; Nico G Hartwig
Reviewing Omenn syndrome.
European journal of pediatrics 2001;160(12):718-25.
2001: Mette D Hazenberg; M C Verschuren; Dörte Hamann; Frank Miedema; Jacques J M van Dongen
T cell receptor excision circles as markers for recent thymic emigrants: basic aspects, technical approach, and guidelines for interpretation.
Journal of molecular medicine (Berlin, Germany) 2001;79(11):631-40.
2001: Anton Langerak; Ingrid L M Wolvers-Tettero; Ellen J van Gastel-Mol; M E Oud; Jacques J M van Dongen
Basic helix-loop-helix proteins E2A and HEB induce immature T-cell receptor rearrangements in nonlymphoid cells.
Blood 2001;98(8):2456-65.
2001: E de Vries; Jeroen G Noordzij; T W Kuijpers; Jacques J M van Dongen
Flow cytometric immunophenotyping in the diagnosis and follow-up of immunodeficient children.
European journal of pediatrics 2001;160(10):583-91.
2001: V H J van der Velden; S A Joosten; Marja J Willemse; Elisabeth R van Wering; A W Lankester; Jacques J M van Dongen; P M Hoogerbrugge
Real-time quantitative PCR for detection of minimal residual disease before allogeneic stem cell transplantation predicts outcome in children with acute lymphoblastic leukemia.
Leukemia 2001;15(9):1485-7.
2001: T Szczepański; Marja J Willemse; Elisabeth R van Wering; JF van Weerden; Willem A Kamps; Jacques J M van Dongen
Precursor-B-ALL with D(H)-J(H) gene rearrangements have an immature immunogenotype with a high frequency of oligoclonality and hyperdiploidy of chromosome 14.
Leukemia 2001;15(9):1415-23.
2001: Elisabeth R van Wering; BE van der Linden-Schrever; V H van der Velden; T Szczepański; Jacques J M van Dongen
T-lymphocytes in bone marrow samples of children with acute lymphoblastic leukemia during and after chemotherapy might hamper PCR-based minimal residual disease studies.
Leukemia 2001;15(8):1301-3.
2001: Paulo Lucio; G Gaipa; Ellen G van Lochem; Elisabeth R van Wering; Anna Porwit-MacDonald; T Faria; E Bjorklund; A Biondi; MW Van den Beemd; EA Baars; B Vidriales; Antonio Parreira; Jacques J M van Dongen; Jesús F San Miguel; Alberto Orfao
BIOMED-I concerted action report: flow cytometric immunophenotyping of precursor B-ALL with standardized triple-stainings. BIOMED-1 Concerted Action Investigation of Minimal Residual Disease in Acute Leukemia: International Standardization and Clinical Evaluation.
Leukemia 2001;15(8):1185-92.
2001: V H J van der Velden; Marja J Willemse; M F Mulder; T Szczepański; Anton Langerak; JM Wijkhuijs; Jacques J M van Dongen
Clearance of maternal leukaemic cells in a neonate.
British journal of haematology 2001;114(1):104-6.
2001: Mirjam van der Burg; Barbara H Barendregt; Elisabeth R van Wering; Anton Langerak; T Szczepański; Jacques J M van Dongen
The presence of somatic mutations in immunoglobulin genes of B cell acute lymphoblastic leukemia (ALL-L3) supports assignment as Burkitt's leukemia-lymphoma rather than B-lineage ALL.
Leukemia 2001;15(7):1141-3.
2001: Eric L Sievers; Richard A Larson; Edward A Stadtmauer; E Estey; Bob Löwenberg; Hervé Dombret; Chatchada Karanes; M Theobald; John M Bennett; Matthew L Sherman; Mark S Berger; Catharine B Eten; Michael R Loken; Jacques J M van Dongen; Irwin D Bernstein; Frederick R Appelbaum
Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(13):3244-54.
2001: Anton Langerak; J H J M van Krieken; Ingrid L M Wolvers-Tettero; E Kerkhof; AH Mulder; L W Vrints; J W Coebergh; Ed Schuuring; Philip M Kluin; Jacques J M van Dongen
The role of molecular analysis of immunoglobulin and T cell receptor gene rearrangements in the diagnosis of lymphoproliferative disorders.
Journal of clinical pathology 2001;54(7):565-7.
2001: Anton Langerak; RW van den Beemd; Ingrid L M Wolvers-Tettero; P P Boor; Ellen G van Lochem; Herbert Hooijkaas; Jacques J M van Dongen
Molecular and flow cytometric analysis of the Vbeta repertoire for clonality assessment in mature TCRalphabeta T-cell proliferations.
Blood 2001;98(1):165-73.
2001: V H J van der Velden; C Schoch; Anton Langerak; S Schnittger; Patricia G Hoogeveen; Jacques J M van Dongen
Low frequency of reverse transcription polymerase chain reaction-detectable chromosome aberrations in relapsed acute myeloid leukaemia: implications for detection of minimal residual disease.
British journal of haematology 2001;113(4):1082-3.
2001: Marc Bierings; T Szczepański; Elisabeth R van Wering; Marja J Willemse; Anton Langerak; Tom Révész; Jacques J M van Dongen
Two consecutive immunophenotypic switches in a child with immunogenotypically stable acute leukaemia.
British journal of haematology 2001;113(3):757-62.
2001: V H J van der Velden; Jeroen te Marvelde; Patricia G Hoogeveen; Irwin D Bernstein; A B Houtsmuller; M S Berger; Jacques J M van Dongen
Targeting of the CD33-calicheamicin immunoconjugate Mylotarg (CMA-676) in acute myeloid leukemia: in vivo and in vitro saturation and internalization by leukemic and normal myeloid cells.
Blood 2001;97(10):3197-204.
2001: T Szczepański; Marja J Willemse; Willem A Kamps; Elisabeth R van Wering; Anton Langerak; Jacques J M van Dongen
Molecular discrimination between relapsed and secondary acute lymphoblastic leukemia: proposal for an easy strategy.
Medical and pediatric oncology 2001;36(3):352-8.
2001: Mirjam van der Burg; Talip Tümkaya; Marjan Boerma; Sandra de Bruin-Versteeg; Anton Langerak; Jacques J M van Dongen
Ordered recombination of immunoglobulin light chain genes occurs at the IGK locus but seems less strict at the IGL locus.
Blood 2001;97(4):1001-8.
2001: Talip Tümkaya; Mirjam van der Burg; R Garcia Sanz; M Gonzalez Diaz; Anton Langerak; JF San Miguel; Jacques J M van Dongen
Immunoglobulin lambda isotype gene rearrangements in B cell malignancies.
Leukemia 2001;15(1):121-7.
2000: Andrea Biondi; M G Valsecchi; Taku Seriu; Elisabetta d'Aniello; Marja J Willemse; Karin Fasching; A Pannunzio; Helmut Gadner; Martin Schrappe; Willem A Kamps; Claus R Bartram; Jacques J M van Dongen; E Renate Panzer-Grümayer
Molecular detection of minimal residual disease is a strong predictive factor of relapse in childhood B-lineage acute lymphoblastic leukemia with medium risk features. A case control study of the International BFM study group.
Leukemia 2000;14(11):1939-43.
2000: Mette D Hazenberg; Sigrid A Otto; James W T Cohen Stuart; M C Verschuren; Jan C C Borleffs; Charles A B Boucher; Roel A Coutinho; Joep M A Lange; Tobias F Rinke de Wit; Aster Tsegaye; Jacques J M van Dongen; Dörte Hamann; Rob J De Boer; Frank Miedema
Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection.
Nature medicine 2000;6(9):1036-42.
2000: Onno J H M Verhagen; Marja J Willemse; Willemijn B Breunis; A J M Wijkhuijs; D C H Jacobs; S A Joosten; Elisabeth R van Wering; Jacques J M van Dongen; C Ellen van der Schoot
Application of germline IGH probes in real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia.
Leukemia 2000;14(8):1426-35.
2000: RW van den Beemd; P P Boor; Ellen G van Lochem; Wim C J Hop; Anton Langerak; Ingrid L M Wolvers-Tettero; Herbert Hooijkaas; Jacques J M van Dongen
Flow cytometric analysis of the Vbeta repertoire in healthy controls.
Cytometry 2000;40(4):336-45.
2000: T Szczepański; Mars B van 't Veer; Ingrid L M Wolvers-Tettero; Anton Langerak; Jacques J M van Dongen
Molecular features responsible for the absence of immunoglobulin heavy chain protein synthesis in an IgH(-) subgroup of multiple myeloma.
Blood 2000;96(3):1087-93.
2000: Elisabeth R van Wering; BE van der Linden-Schrever; T Szczepański; Marja J Willemse; EA Baars; H M van Wijngaarde-Schmitz; Willem A Kamps; Jacques J M van Dongen
Regenerating normal B-cell precursors during and after treatment of acute lymphoblastic leukaemia: implications for monitoring of minimal residual disease.
British journal of haematology 2000;110(1):139-46.
2000: T Szczepański; Anton Langerak; Marja J Willemse; Ingrid L M Wolvers-Tettero; Elisabeth R van Wering; Jacques J M van Dongen
T cell receptor gamma (TCRG) gene rearrangements in T cell acute lymphoblastic leukemia refelct 'end-stage' recombinations: implications for minimal residual disease monitoring.
Leukemia 2000;14(7):1208-14.
2000: Jeroen G Noordzij; Nicole S Verkaik; Nico G Hartwig; Ronald de Groot; Dik C van Gent; Jacques J M van Dongen
N-terminal truncated human RAG1 proteins can direct T-cell receptor but not immunoglobulin gene rearrangements.
Blood 2000;96(1):203-9.
2000: E de Vries; Sandra de Bruin-Versteeg; W Marieke Comans-Bitter; Ronald de Groot; Wim C J Hop; GJ Boerma; Fred K Lotgering; Pieter J J Sauer; Jacques J M van Dongen
Neonatal blood lymphocyte subpopulations: a different perspective when using absolute counts.
Biology of the neonate 2000;77(4):230-5.
2000: Anna Porwit-MacDonald; Elisabet Björklund; Paulo Lucio; Ellen G van Lochem; Joanna Mazur; Antonio Parreira; MW Van den Beemd; Elisabeth R van Wering; EA Baars; G Gaipa; A Biondi; Juana Ciudad; Jacques J M van Dongen; Jesús F San Miguel; Alberto Orfao
BIOMED-1 concerted action report: flow cytometric characterization of CD7+ cell subsets in normal bone marrow as a basis for the diagnosis and follow-up of T cell acute lymphoblastic leukemia (T-ALL).
Leukemia 2000;14(5):816-25.
2000: Ellen G van Lochem; Y M Wiegers; RW van den Beemd; Karel Hählen; Jacques J M van Dongen; Herbert Hooijkaas
Regeneration pattern of precursor-B-cells in bone marrow of acute lymphoblastic leukemia patients depends on the type of preceding chemotherapy.
Leukemia 2000;14(4):688-95.
2000: E de Vries; Sandra de Bruin-Versteeg; W Marieke Comans-Bitter; Ronald de Groot; Wim C J Hop; GJ Boerma; Fred K Lotgering; Jacques J M van Dongen
Longitudinal survey of lymphocyte subpopulations in the first year of life.
Pediatric research 2000;47(4 Pt 1):528-37.
2000: Mirjam van der Burg; Ronald de Groot; W Marieke Comans-Bitter; J C den Hollander; Herbert Hooijkaas; H J Neijens; Rolf M F Berger; Arnold P Oranje; Anton Langerak; Jacques J M van Dongen
Autoimmune lymphoproliferative syndrome (ALPS) in a child from consanguineous parents: a dominant or recessive disease?
Pediatric research 2000;47(3):336-43.
2000: William J Romanow; Anton Langerak; Peter Goebel; Ingrid L M Wolvers-Tettero; Jacques J M van Dongen; Ann J Feeney; Cornelis Murre
E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells.
Molecular cell 2000;5(2):343-53.
1999: Jesús F San Miguel; Juana Ciudad; María-Belén Vidriales; Alberto Orfao; Paulo Lucio; A Porwit-MacDonald; G Gaipa; E van Wering; Jacques J M van Dongen
Immunophenotypical detection of minimal residual disease in acute leukemia.
Critical reviews in oncology/hematology 1999;32(3):175-85.
1999: Mirjam van der Burg; Berna Beverloo; Anton Langerak; J Wijsman; Ellen van Drunen; Rosalyn Slater; Jacques J M van Dongen
Rapid and sensitive detection of all types of MLL gene translocations with a single FISH probe set.
Leukemia 1999;13(12):2107-13.
1999: Jacques J M van Dongen; Elizabeth Macintyre; Jean Gabert; Eric Delabesse; V Rossi; Giuseppe Saglio; Enrico Gottardi; A Rambaldi; G Dotti; F Griesinger; A Parreira; Paula Gameiro; M G Diáz; Maria Malec; Anton Langerak; JF San Miguel; Andrea Biondi
Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: investigation of minimal residual disease in acute leukemia.
Leukemia 1999;13(12):1901-28.
1999: E J Moreau; Anton Langerak; Ellen J van Gastel-Mol; Ingrid L M Wolvers-Tettero; M Zhan; Q Zhou; B F Koop; Jacques J M van Dongen
Easy detection of all T cell receptor gamma (TCRG) gene rearrangements by Southern blot analysis: recommendations for optimal results.
Leukemia 1999;13(10):1620-6.
1999: E de Vries; Jeroen G Noordzij; E G Davies; Nico G Hartwig; M H Breuning; Jacques J M van Dongen; Maarten J D van Tol
The 78C --> T (T254M) XHIM mutation: lack of a tight phenotype-genotype relationship.
Blood 1999;94(4):1488-90.
1999: P W Derksen; Anton Langerak; E Kerkhof; Ingrid L M Wolvers-Tettero; P P Boor; AH Mulder; L W Vrints; J W Coebergh; J H J M van Krieken; Ed Schuuring; Philip M Kluin; Jacques J M van Dongen
Comparison of different polymerase chain reaction-based approaches for clonality assessment of immunoglobulin heavy-chain gene rearrangements in B-cell neoplasia.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1999;12(8):794-805.
1999: Onno J H M Verhagen; A J M Wijkhuijs; AJ van der Sluijs-Gelling; T Szczepański; BE van der Linden-Schrever; MJ Pongers-Willemse; Elisabeth R van Wering; Jacques J M van Dongen; C Ellen van der Schoot
Suitable DNA isolation method for the detection of minimal residual disease by PCR techniques.
Leukemia 1999;13(8):1298-9.
1999: E de Vries; Ronald de Groot; Sandra de Bruin-Versteeg; W Marieke Comans-Bitter; Jacques J M van Dongen
Analysing the developing lymphocyte system of neonates and infants.
European journal of pediatrics 1999;158(8):611-7.
1999: T Szczepański; MJ Pongers-Willemse; Anton Langerak; W A Harts; A J M Wijkhuijs; Elisabeth R van Wering; Jacques J M van Dongen
Ig heavy chain gene rearrangements in T-cell acute lymphoblastic leukemia exhibit predominant DH6-19 and DH7-27 gene usage, can result in complete V-D-J rearrangements, and are rare in T-cell receptor alpha beta lineage.
Blood 1999;93(12):4079-85.
1999: Anton Langerak; Ingrid L M Wolvers-Tettero; Jacques J M van Dongen
Detection of T cell receptor beta (TCRB) gene rearrangement patterns in T cell malignancies by Southern blot analysis.
Leukemia 1999;13(6):965-74.
1999: Bianca Blom; Mirjam H M Heemskerk; M C M Verschuren; Jacques J M van Dongen; AP Stegmann; Arjen Q Bakker; Franka Couwenberg; PC Res; Hergen Spits
Disruption of alpha beta but not of gamma delta T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors.
The EMBO journal 1999;18(10):2793-802.
1999: Bianca Blom; M C M Verschuren; Mirjam H M Heemskerk; Arjen Q Bakker; Ellen J van Gastel-Mol; Ingrid L M Wolvers-Tettero; Jacques J M van Dongen; Hergen Spits
TCR gene rearrangements and expression of the pre-T cell receptor complex during human T-cell differentiation.
Blood 1999;93(9):3033-43.
1999: E de Vries; Sandra de Bruin-Versteeg; W Marieke Comans-Bitter; Ronald de Groot; GJ Boerma; Fred K Lotgering; Jacques J M van Dongen
Correction for erythroid cell contamination in microassay for immunophenotyping of neonatal lymphocytes.
Archives of disease in childhood. Fetal and neonatal edition 1999;80(3):F226-9.
1999: Juana Ciudad; Jesús F San Miguel; Ma Consuelo López-Berges; María Antonia García-Marcos; Marcos González; Lourdes Vázquez; Maria Consuelo Del Cañizo; Antonio López; Jacques J M van Dongen; Alberto Orfao
Detection of abnormalities in B-cell differentiation pattern is a useful tool to predict relapse in precursor-B-ALL.
British journal of haematology 1999;104(4):695-705.
1999: Paulo Lucio; Antonio Parreira; MW Van den Beemd; Ellen G van Lochem; Elisabeth R van Wering; EA Baars; Anna Porwit-MacDonald; E Bjorklund; G Gaipa; A Biondi; Alberto Orfao; G Janossy; Jacques J M van Dongen; Jesús F San Miguel
Flow cytometric analysis of normal B cell differentiation: a frame of reference for the detection of minimal residual disease in precursor-B-ALL.
Leukemia 1999;13(3):419-27.
1999: Anton Langerak; Ingrid L M Wolvers-Tettero; MW Van den Beemd; Elisabeth R van Wering; W D Ludwig; Karel Hählen; A Necker; Jacques J M van Dongen
Immunophenotypic and immunogenotypic characteristics of TCRgammadelta+ T cell acute lymphoblastic leukemia.
Leukemia 1999;13(2):206-14.
1999: T Szczepański; Auke Beishuizen; MJ Pongers-Willemse; Karel Hählen; Elisabeth R van Wering; A J M Wijkhuijs; GJ Tibbe; MA de Bruijn; Jacques J M van Dongen
Cross-lineage T cell receptor gene rearrangements occur in more than ninety percent of childhood precursor-B acute lymphoblastic leukemias: alternative PCR targets for detection of minimal residual disease.
Leukemia 1999;13(2):196-205.
1999: T Szczepański; MJ Pongers-Willemse; Anton Langerak; Jacques J M van Dongen
Unusual immunoglobulin and T-cell receptor gene rearrangement patterns in acute lymphoblastic leukemias.
Current topics in microbiology and immunology 1999;246():205-13; discussion 214-5.
1999: MJ Pongers-Willemse; Taku Seriu; F Stolz; Elisabetta d'Aniello; Paula Gameiro; P Pisa; M Gonzalez; Claus R Bartram; E Renate Panzer-Grümayer; Andrea Biondi; JF San Miguel; Jacques J M van Dongen
Primers and protocols for standardized detection of minimal residual disease in acute lymphoblastic leukemia using immunoglobulin and T cell receptor gene rearrangements and TAL1 deletions as PCR targets: report of the BIOMED-1 CONCERTED ACTION: investigation of minimal residual disease in acute leukemia.
Leukemia 1999;13(1):110-8.
1998: M C M Verschuren; Bianca Blom; A J Bogers; Hergen Spits; Jacques J M van Dongen
PJA-BP expression and TCR delta deletion during human T cell differentiation.
International immunology 1998;10(12):1873-80.
1998: MJ Pongers-Willemse; Onno J H M Verhagen; GJ Tibbe; A J M Wijkhuijs; V de Haas; E Roovers; C Ellen van der Schoot; Jacques J M van Dongen
Real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia using junctional region specific TaqMan probes.
Leukemia 1998;12(12):2006-14.
1998: Jacques J M van Dongen; Taku Seriu; E Renate Panzer-Grümayer; Andrea Biondi; MJ Pongers-Willemse; L Corral; F Stolz; Martin Schrappe; Guiseppe Masera; Willem A Kamps; Helmut Gadner; Elisabeth R van Wering; W D Ludwig; G Basso; MA de Bruijn; Giovanni Cazzaniga; Klaudia Hettinger; Anna van der Does-van den Berg; Wim C J Hop; Hansjörg Riehm; Claus R Bartram
Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood.
Lancet 1998;352(9142):1731-8.
1998: Hergen Spits; Bianca Blom; AC Jaleco; Kees Weijer; M C M Verschuren; Jacques J M van Dongen; Mirjam H M Heemskerk; PC Res
Early stages in the development of human T, natural killer and thymic dendritic cells.
Immunological reviews 1998;165():75-86.
1998: E de Vries; Sandra de Bruin-Versteeg; W Marieke Comans-Bitter; Jacques J M van Dongen; Ronald de Groot; GJ Boerma; Fred K Lotgering
Longitudinal follow-up of blood lymphocyte subpopulations from birth to 1 year of age.
The Journal of pediatrics 1998;133(4):586-8.
1998: T Szczepański; MJ Pongers-Willemse; Karel Hählen; Jacques J M van Dongen
Intensified therapy for infants with acute lymphoblastic leukemia: results from the Dana-Farber Cancer Institute Consortium.
Cancer 1998;83(5):1055-7.
1998: T Szczepański; Anton Langerak; Jacques J M van Dongen; J H J M van Krieken
Lymphoma with multi-gene rearrangement on the level of immunoglobulin heavy chain, light chain, and T-cell receptor beta chain.
American journal of hematology 1998;59(1):99-100.
1998: T Szczepański; Anton Langerak; Ingrid L M Wolvers-Tettero; Gert Ossenkoppele; G Verhoef; Michel Stul; E J Petersen; MA de Bruijn; Mars B van't Veer; Jacques J M van Dongen
Immunoglobulin and T cell receptor gene rearrangement patterns in acute lymphoblastic leukemia are less mature in adults than in children: implications for selection of PCR targets for detection of minimal residual disease.
Leukemia 1998;12(7):1081-8.
1998: Hanneke C Kluin-Nelemans; Michel Kester; L van deCorput; P P Boor; JE Landegent; Jacques J M van Dongen; Rein Willemze; J H Frederik Falkenburg
Correction of abnormal T-cell receptor repertoire during interferon-alpha therapy in patients with hairy cell leukemia.
Blood 1998;91(11):4224-31.
1998: ME Massari; Richard R Rivera; J R Voland; Melanie W Quong; T M Breit; Jacques J M van Dongen; O de Smit; Cornelis Murre
Characterization of ABF-1, a novel basic helix-loop-helix transcription factor expressed in activated B lymphocytes.
Molecular and cellular biology 1998;18(6):3130-9.
1998: M C M Verschuren; Ingrid L M Wolvers-Tettero; TM Breit; Jacques J M van Dongen
T-cell receptor V delta-J alpha rearrangements in human thymocytes: the role of V delta-J alpha rearrangements in T-cell receptor-delta gene deletion.
Immunology 1998;93(2):208-12.
1997: Ellen G van Lochem; Kees Groeneveld; Jeroen te Marvelde; MW Van den Beemd; Herbert Hooijkaas; Jacques J M van Dongen
Flow cytometric detection of intracellular antigens for immunophenotyping of normal and malignant leukocytes: testing of a new fixation-permeabilization solution.
Leukemia 1997;11(12):2208-10.
1997: Auke Beishuizen; MA de Bruijn; MJ Pongers-Willemse; M A Verhoeven; Elisabeth R van Wering; Karel Hählen; TM Breit; Sandra de Bruin-Versteeg; Herbert Hooijkaas; Jacques J M van Dongen
Heterogeneity in junctional regions of immunoglobulin kappa deleting element rearrangements in B cell leukemias: a new molecular target for detection of minimal residual disease.
Leukemia 1997;11(12):2200-7.
1997: Anton Langerak; T Szczepański; Mirjam van der Burg; Ingrid L M Wolvers-Tettero; Jacques J M van Dongen
Heteroduplex PCR analysis of rearranged T cell receptor genes for clonality assessment in suspect T cell proliferations.
Leukemia 1997;11(12):2192-9.
1997: TM Breit; M C M Verschuren; Ingrid L M Wolvers-Tettero; Ellen J van Gastel-Mol; Karel Hählen; Jacques J M van Dongen
Human T cell leukemias with continuous V(D)J recombinase activity for TCR-delta gene deletion.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(9):4341-9.
1997: MA Hoijer; Marie-José Melief; J Calafat; D Roos; RW van den Beemd; Jacques J M van Dongen; MP Hazenberg
Expression and intracellular localization of the human N-acetylmuramyl-L-alanine amidase, a bacterial cell wall-degrading enzyme.
Blood 1997;90(3):1246-54.
1997: W Marieke Comans-Bitter; Ronald de Groot; RW van den Beemd; H J Neijens; Wim C J Hop; Kees Groeneveld; Herbert Hooijkaas; Jacques J M van Dongen
Immunophenotyping of blood lymphocytes in childhood. Reference values for lymphocyte subpopulations.
The Journal of pediatrics 1997;130(3):388-93.
1997: M C M Verschuren; Ingrid L M Wolvers-Tettero; TM Breit; Jeroen G Noordzij; Elisabeth R van Wering; Jacques J M van Dongen
Preferential rearrangements of the T cell receptor-delta-deleting elements in human T cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(3):1208-16.
1996: T Tümkaya; Auke Beishuizen; Ingrid L M Wolvers-Tettero; Jacques J M van Dongen
Identification of immunoglobulin lambda isotype gene rearrangements by Southern blot analysis.
Leukemia 1996;10(11):1834-9.
1996: Kees Groeneveld; Jeroen te Marvelde; MW Van den Beemd; Herbert Hooijkaas; Jacques J M van Dongen
Flow cytometric detection of intracellular antigens for immunophenotyping of normal and malignant leukocytes.
Leukemia 1996;10(8):1383-9.
1996: Jacques J M van Dongen; T Szczepański; MA de Bruijn; MW Van den Beemd; Sandra de Bruin-Versteeg; J M Wijkhuijs; GJ Tibbe; Ellen J van Gastel-Mol; Kees Groeneveld; Herbert Hooijkaas
Detection of minimal residual disease in acute leukemia patients.
Cytokines and molecular therapy 1996;2(2):121-33.
1996: M C M Verschuren; C J van Bergen; Ellen J van Gastel-Mol; A J Bogers; Jacques J M van Dongen
A DNA binding protein in human thymocytes recognizes the T cell receptor-delta-deleting element psi J alpha.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(10):3806-14.
1995: Jacques J M van Dongen
Proposals for immunological classification of acute leukemias.
Leukemia 1995;9(12):2149-50.
1995: T Tümkaya; W Marieke Comans-Bitter; M A Verhoeven; Jacques J M van Dongen
Southern blot detection of immunoglobulin lambda light chain gene rearrangements for clonality studies.
Leukemia 1995;9(12):2127-32.
1995: Elisabeth R van Wering; Auke Beishuizen; E T Roeffen; B E van der Linden-Schrever; M A Verhoeven; Karel Hählen; Herbert Hooijkaas; Jacques J M van Dongen
Immunophenotypic changes between diagnosis and relapse in childhood acute lymphoblastic leukemia.
Leukemia 1995;9(9):1523-33.
1994: Auke Beishuizen; M A Verhoeven; E J Mol; Jacques J M van Dongen
Detection of immunoglobulin kappa light-chain gene rearrangement patterns by Southern blot analysis.
Leukemia 1994;8(12):2228-36; discussion 2237-9.
1994: TM Breit; Ingrid L M Wolvers-Tettero; Jacques J M van Dongen
Lineage specific demethylation of tal-1 gene breakpoint region determines the frequency of tal-1 deletions in alpha beta lineage T-cells.
Oncogene 1994;9(7):1847-53.
1994: Auke Beishuizen; M A Verhoeven; Elisabeth R van Wering; Karel Hählen; Herbert Hooijkaas; Jacques J M van Dongen
Analysis of Ig and T-cell receptor genes in 40 childhood acute lymphoblastic leukemias at diagnosis and subsequent relapse: implications for the detection of minimal residual disease by polymerase chain reaction analysis.
Blood 1994;83(8):2238-47.
1994: TM Breit; Ingrid L M Wolvers-Tettero; Jacques J M van Dongen
Unique selection determinant in polyclonal V delta 2-J delta 1 junctional regions of human peripheral gamma delta T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(6):2860-4.
1994: TM Breit; Ingrid L M Wolvers-Tettero; Jacques J M van Dongen
Phenotypic and genotypic characteristics of human early T-cell differentiation: the T-cell acute lymphoblastic leukaemia model.
Research in immunology 1994;145(2):139-43; discussion 155-8.
1994: TM Breit; Ingrid L M Wolvers-Tettero; A J Bogers; Ronald R de Krijger; J W Wladimiroff; Jacques J M van Dongen
Rearrangements of the human TCRD-deleting elements.
Immunogenetics 1994;40(1):70-5.
1994: Frans J Los; JO van Hemel; H J Jacobs; Stenvert L S Drop; Jacques J M van Dongen
De novo deletion (2) (p11.2p13): clinical, cytogenetic, and immunological data.
Journal of medical genetics 1994;31(1):72-3.
1994: TM Breit; Jacques J M van Dongen
Unravelling human T-cell receptor junctional region sequences.
Thymus 1994;22(3):177-99.
1993: TM Breit; Auke Beishuizen; W D Ludwig; E J Mol; H J Adriaansen; Elisabeth R van Wering; Jacques J M van Dongen
tal-1 deletions in T-cell acute lymphoblastic leukemia as PCR target for detection of minimal residual disease.
Leukemia 1993;7(12):2004-11.
1993: M C M Verschuren; W Marieke Comans-Bitter; C A Kapteijn; David Y Mason; Gaby Brouns; Jannie Borst; H G Drexler; Jacques J M van Dongen
Transcription and protein expression of mb-1 and B29 genes in human hematopoietic malignancies and cell lines.
Leukemia 1993;7(12):1939-47.
1993: Auke Beishuizen; M A Verhoeven; E J Mol; TM Breit; Ingrid L M Wolvers-Tettero; Jacques J M van Dongen
Detection of immunoglobulin heavy-chain gene rearrangements by Southern blot analysis: recommendations for optimal results.
Leukemia 1993;7(12):2045-53.
1993: TM Breit; Ingrid L M Wolvers-Tettero; Auke Beishuizen; M A Verhoeven; Elisabeth R van Wering; Jacques J M van Dongen
Southern blot patterns, frequencies, and junctional diversity of T-cell receptor-delta gene rearrangements in acute lymphoblastic leukemia.
Blood 1993;82(10):3063-74.
1993: Pieter Sonneveld; Jacques J M van Dongen; Anne Hagemeijer; Kirsten van Lom; Kees Nooter; M Schoester; H J Adriaansen; T Tsuruo; K de Leeuw
High expression of the multidrug resistance P-glycoprotein in high-risk myelodysplasia is associated with immature phenotype.
Leukemia 1993;7(7):963-9.
1993: Auke Beishuizen; M A Verhoeven; Karel Hählen; Elisabeth R van Wering; Jacques J M van Dongen
Differences in immunoglobulin heavy chain gene rearrangmeent patterns between bone marrow and blood samples in childhood precursor B-acute lymphoblastic leaukemia at diagnosis.
Leukemia 1993;7(6):60-3.
1993: H J Adriaansen; P A te Boekhorst; Anne Hagemeijer; C Ellen van der Schoot; H R Delwel; Jacques J M van Dongen
Acute myeloid leukemia M4 with bone marrow eosinophilia (M4Eo) and inv(16)(p13q22) exhibits a specific immunophenotype with CD2 expression.
Blood 1993;81(11):3043-51.
1993: A C Knulst; H J Adriaansen; Karel Hählen; J C Stigter; MW Van den Beemd; Anne Hagemeijer; Jacques J M van Dongen; Herbert Hooijkaas
Early diagnosis of smoldering acute lymphoblastic leukemia using immunological marker analysis.
Leukemia 1993;7(4):532-6.
1993: TM Breit; E J Mol; Ingrid L M Wolvers-Tettero; W D Ludwig; Elisabeth R van Wering; Jacques J M van Dongen
Site-specific deletions involving the tal-1 and sil genes are restricted to cells of the T cell receptor alpha/beta lineage: T cell receptor delta gene deletion mechanism affects multiple genes.
The Journal of experimental medicine 1993;177(4):965-77.
1993: Jannie Borst; Gaby Brouns; Evert de Vries; M C M Verschuren; David Y Mason; Jacques J M van Dongen
Antigen receptors on T and B lymphocytes: parallels in organization and function.
Immunological reviews 1993;132():49-84.
1993: H J Adriaansen; Bart C Jacobs; M C Kappers-Klunne; Karel Hählen; Herbert Hooijkaas; Jacques J M van Dongen
Detection of residual disease in AML patients by use of double immunological marker analysis for terminal deoxynucleotidyl transferase and myeloid markers.
Leukemia 1993;7(3):472-81.
1993: Elisabeth R van Wering; P Brederoo; G J van Staalduinen; J van der Meulen; B E van der Linden-Schrever; Jacques J M van Dongen
Contribution of electron microscopy to the classification of minimally differentiated acute leukemias in children.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1993;131():77-87.
1993: Jacques J M van Dongen; TM Breit; H J Adriaansen; Auke Beishuizen; Herbert Hooijkaas
Immunophenotypic and immunogenotypic detection of minimal residual disease in acute lymphoblastic leukemia.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1993;131():157-84.
1992: K C Kuijpers; Jacques J M van Dongen; P van der Burg; Marijke Th L Roos; J Vonk; Ronney A De Abreu; D de Korte; Carel J M van Noesel; Ron S Weening; René A W van Lier
A combined immunodeficiency with oligoclonal CD8+, V beta 3-expressing, cytotoxic T lymphocytes in the peripheral blood.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(10):3403-10.
1992: David Y Mason; Carel J M van Noesel; J L Cordell; W Marieke Comans-Bitter; K Micklem; A G Tse; René A W van Lier; Jacques J M van Dongen
The B29 and mb-1 polypeptides are differentially expressed during human B cell differentiation.
European journal of immunology 1992;22(10):2753-6.
1992: J W van Oostveen; T M Breit; J Th M de Wolf; R M Brandt; Jan W Smit; Jacques J M van Dongen; Jannie Borst; Cornelis J M Melief
Polyclonal expansion of T-cell receptor-gamma delta+ T lymphocytes associated with neutropenia and thrombocytopenia.
Leukemia 1992;6(5):410-8.
1992: Pieter Sonneveld; Kees Nooter; J T Burghouts; H Herweijer; H J Adriaansen; Jacques J M van Dongen
High expression of the mdr3 multidrug-resistance gene in advanced-stage chronic lymphocytic leukemia.
Blood 1992;79(6):1496-500.
1992: TM Breit; L M Wolvers-Tettero; Karel Hählen; Elisabeth R van Wering; Jacques J M van Dongen
Extensive junctional diversity of gamma delta T-cell receptors expressed by T-cell acute lymphoblastic leukemias: implications for the detection of minimal residual disease.
Leukemia 1992;6(2):169-70.
1992: Jacques J M van Dongen; TM Breit; H J Adriaansen; Auke Beishuizen; Herbert Hooijkaas
Detection of minimal residual disease in acute leukemia by immunological marker analysis and polymerase chain reaction.
Leukemia 1992;6 Suppl 1():47-59.
1992: TM Breit; Ingrid L M Wolvers-Tettero; Jacques J M van Dongen
Receptor diversity of human T-cell receptor gamma delta expressing cells.
Progress in histochemistry and cytochemistry 1992;26(1-4):182-93.
1991: TM Breit; Ingrid L M Wolvers-Tettero; Karel Hählen; Elisabeth R van Wering; Jacques J M van Dongen
Extensive junctional diversity of gamma delta T-cell receptors expressed by T-cell acute lymphoblastic leukemias: implications for the detection of minimal residual disease.
Leukemia 1991;5(12):1076-86.
1991: David Y Mason; J L Cordell; A G Tse; Jacques J M van Dongen; Carel J M van Noesel; K Micklem; Karen Pulford; F Valensi; W Marieke Comans-Bitter; Jannie Borst
The IgM-associated protein mb-1 as a marker of normal and neoplastic B cells.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(11):2474-82.
1991: H J Adriaansen; P W Soeting; Ingrid L M Wolvers-Tettero; Jacques J M van Dongen
Immunoglobulin and T-cell receptor gene rearrangements in acute non-lymphocytic leukemias. Analysis of 54 cases and a review of the literature.
Leukemia 1991;5(9):744-51.
1991: Auke Beishuizen; Karel Hählen; Anne Hagemeijer; M A Verhoeven; Herbert Hooijkaas; H J Adriaansen; Ingrid L M Wolvers-Tettero; Elisabeth R van Wering; Jacques J M van Dongen
Multiple rearranged immunoglobulin genes in childhood acute lymphoblastic leukemia of precursor B-cell origin.
Leukemia 1991;5(8):657-67.
1991: Jacques J M van Dongen; Ingrid L M Wolvers-Tettero
Analysis of immunoglobulin and T cell receptor genes. Part II: Possibilities and limitations in the diagnosis and management of lymphoproliferative diseases and related disorders.
Clinica chimica acta; international journal of clinical chemistry 1991;198(1-2):93-174.
1991: Jacques J M van Dongen; Ingrid L M Wolvers-Tettero
Analysis of immunoglobulin and T cell receptor genes. Part I: Basic and technical aspects.
Clinica chimica acta; international journal of clinical chemistry 1991;198(1-2):1-91.
1991: Ger T Rijkers; J G Scharenberg; Jacques J M van Dongen; H J Neijens; BJ Zegers
Abnormal signal transduction in a patient with severe combined immunodeficiency disease.
Pediatric research 1991;29(3):306-9.
1991: TM Breit; Ingrid L M Wolvers-Tettero; Karel Hählen; Elisabeth R van Wering; Jacques J M van Dongen
Limited combinatorial repertoire of gamma delta T-cell receptors expressed by T-cell acute lymphoblastic leukemias.
Leukemia 1991;5(2):116-24.
1991: Jannie Borst; T M Vroom; J D Bos; Jacques J M van Dongen
Tissue distribution and repertoire selection of human gamma delta T cells: comparison with the murine system.
Current topics in microbiology and immunology 1991;173():41-6.
1991: H Herweijer; Kees Nooter; A Beishuizen; Pieter Sonneveld; R G Oostrum; A L Hesseling-Janssen; Jacques J M van Dongen
Expression of mdr1 and mdr3 multidrug-resistance genes in hairy cell leukaemia.
European journal of cancer (Oxford, England : 1990) 1991;27(3):297-8.
1991: Theo Van der Kwast; Jacques J M van Dongen; J J Michiels; Herbert Hooijkaas; M C Kappers; Anne Hagemeijer
T-lymphoblastic lymphoma terminating as malignant histiocytosis with rearrangement of immunoglobulin heavy chain gene.
Leukemia 1991;5(1):78-82.
1990: H J Adriaansen; C Osman; Jacques J M van Dongen; J H Wijdenes-de Bresser; C M Kappetijn-van Tilborg; Herbert Hooijkaas
Immunological marker analysis of mitogen-induced proliferating lymphocytes using BrdU incorporation or screening of metaphases. Staphylococcal protein A is a potent mitogen for CD4+ lymphocytes.
Scandinavian journal of immunology 1990;32(6):687-94.
1990: Jacques J M van Dongen; W Marieke Comans-Bitter; Ingrid L M Wolvers-Tettero; Jannie Borst
Development of human T lymphocytes and their thymus-dependency.
Thymus 1990;16(3-4):207-34.
1990: Jannie Borst; Jacques J M van Dongen; Evert de Vries; W Marieke Comans-Bitter; M J van Tol; J M Vossen; R Kurrle
BMA031, a monoclonal antibody suited to identify the T-cell receptor alpha beta/CD3 complex on viable human T lymphocytes in normal and disease states.
Human immunology 1990;29(3):175-88.
1990: Jannie Borst; Jacques J M van Dongen
Repertoire selection of human gamma delta T cells.
Research in immunology 1990;141(7):663-8.
1990: H J Adriaansen; Jacques J M van Dongen; M C Kappers-Klunne; Karel Hählen; M B van 't Veer; J H Wijdenes-de Bresser; A C Holdrinet; E J Harthoorn-Lasthuizen; J Abels; Herbert Hooijkaas
Terminal deoxynucleotidyl transferase positive subpopulations occur in the majority of ANLL: implications for the detection of minimal disease.
Leukemia 1990;4(6):404-10.
1990: David Y Mason; W Marieke Comans-Bitter; J L Cordell; M A Verhoeven; Jacques J M van Dongen
Antibody L26 recognizes an intracellular epitope on the B-cell-associated CD20 antigen.
The American journal of pathology 1990;136(6):1215-22.
1990: H J Adriaansen; A H Guerts van Kessel; J H Wijdenes-de Bresser; E van Drunen-Schoenmaker; Jacques J M van Dongen
Expression of the myeloid differentiation antigen CD33 depends on the presence of human chromosome 19 in human-mouse hybrids.
Annals of human genetics 1990;54(Pt 2):115-9.
1990: H J Adriaansen; Herbert Hooijkaas; M C Kappers-Klunne; Karel Hählen; Mars B van't Veer; Jacques J M van Dongen
Double marker analysis for terminal deoxynucleotidyl transferase and myeloid antigens in acute nonlymphocytic leukemia patients and healthy subjects.
Haematology and blood transfusion 1990;33():41-9.
1989: H J Neijens; J Frenkel; Sabine M P F de Muinck Keizer-Schrama; G Dzoljic-Danilovic; Morteza Meradji; Jacques J M van Dongen
Invasive Aspergillus infection in chronic granulomatous disease: treatment with itraconazole.
The Journal of pediatrics 1989;115(6):1016-9.
1989: J J Michiels; Jacques J M van Dongen; Anne Hagemeijer; Pieter Sonneveld; Rob E Ploemacher; H J Adriaansen; Theo Van der Kwast; P Brederoo; J Abels
Richter's syndrome with identical immunoglobulin gene rearrangements in the chronic lymphocytic leukemia and the supervening non-Hodgkin lymphoma.
Leukemia 1989;3(11):819-24.
1989: Jannie Borst; A Wicherink; Jacques J M van Dongen; Evert de Vries; W Marieke Comans-Bitter; F Wassenaar; P Van Den Elsen
Non-random expression of T cell receptor gamma and delta variable gene segments in functional T lymphocyte clones from human peripheral blood.
European journal of immunology 1989;19(9):1559-68.
1989: Herbert Hooijkaas; Karel Hählen; H J Adriaansen; I Dekker; G E van Zanen; Jacques J M van Dongen
Terminal deoxynucleotidyl transferase (TdT)-positive cells in cerebrospinal fluid and development of overt CNS leukemia: a 5-year follow-up study in 113 children with a TdT-positive leukemia or non-Hodgkin's lymphoma.
Blood 1989;74(1):416-22.
1989: Jacques J M van Dongen; Ingrid L M Wolvers-Tettero; F Wassenaar; Jannie Borst; P van den Elsen
Rearrangement and expression of T-cell receptor delta genes in T-cell acute lymphoblastic leukemias.
Blood 1989;74(1):334-42.
1988: J Frenkel; Herman J Neijens; J C den Hollander; Ingrid L M Wolvers-Tettero; Jacques J M van Dongen
Oligoclonal T cell proliferative disorder in combined immunodeficiency.
Pediatric research 1988;24(5):622-7.
1988: Jannie Borst; Jacques J M van Dongen; R L Bolhuis; Peter J Peters; D A Hafler; Evert de Vries; R J van de Griend
Distinct molecular forms of human T cell receptor gamma/delta detected on viable T cells by a monoclonal antibody.
The Journal of experimental medicine 1988;167(5):1625-44.
1988: Jan Jacques Michiels; H J Adriaansen; Anne Hagemeijer; Herbert Hooijkaas; Jacques J M van Dongen; J Abels
TdT positive B-cell acute lymphoblastic leukaemia (B-ALL) without Burkitt characteristics.
British journal of haematology 1988;68(4):423-6.
1988: H J Adriaansen; Jacques J M van Dongen; Herbert Hooijkaas; Karel Hählen; M B van 't Veer; Bob Löwenberg; Anne Hagemeijer
Translocation (6;9) may be associated with a specific TdT-positive immunological phenotype in ANLL.
Leukemia 1988;2(3):136-40.
1988: Jacques J M van Dongen; G W Krissansen; Ingrid L M Wolvers-Tettero; W Marieke Comans-Bitter; H J Adriaansen; Herbert Hooijkaas; Elisabeth R van Wering; C Terhorst
Cytoplasmic expression of the CD3 antigen as a diagnostic marker for immature T-cell malignancies.
Blood 1988;71(3):603-12.
1987: Jacques J M van Dongen; Ingrid L M Wolvers-Tettero; J G Seidman; S L Ang; R J Van de Griend; E F De Vries; Jannie Borst
Two types of gamma T cell receptors expressed by T cell acute lymphoblastic leukemias.
European journal of immunology 1987;17(12):1719-28.
1987: Jacques J M van Dongen; T Quertermous; C R Bartram; D P Gold; Ingrid L M Wolvers-Tettero; W Marieke Comans-Bitter; Herbert Hooijkaas; H J Adriaansen; A de Klein; A Raghavachar
T cell receptor-CD3 complex during early T cell differentiation. Analysis of immature T cell acute lymphoblastic leukemias (T-ALL) at DNA, RNA, and cell membrane level.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(4):1260-9.
1987: Anne Hagemeijer; Jacques J M van Dongen; R M Slater; Mars B van't Veer; H Behrendt; Karel Hählen; W Sizoo; J Abels
Characterization of the blast cells in acute leukemia with translocation (4;11): report of eight additional cases and of one case with a variant translocation.
Leukemia 1987;1(1):24-31.
1987: Jacques J M van Dongen; W Marieke Comans-Bitter
Phenotypic and genotypic characteristics of the human prothymocyte.
Immunologic research 1987;6(4):250-62.
1986: Herbert Hooijkaas; H J Adriaansen; Karel Hählen; G E van Zanen; Jacques J M van Dongen
[Terminal deoxynucleotidyltransferase (TdT)-positive cells in cerebrospinal fluid of children with leukemia or non-Hodgkin lymphoma: implications for the diagnosis of central nervous system leukemia].
Tijdschrift voor kindergeneeskunde 1986;54(2):46-50.
1986: Jacques J M van Dongen; Herbert Hooijkaas; H J Adriaansen; Karel Hählen; G E van Zanen
[Detection of low numbers of malignant cells in patients with leukemia or non-Hodgkin lymphoma: use of immunological markers].
Tijdschrift voor kindergeneeskunde 1986;54(2):41-5.
1985: Jacques J M van Dongen; Herbert Hooijkaas; M Comans-Bitter; Karel Hählen; A de Klein; G E van Zanen; Mars B van't Veer; J Abels; R Benner
Human bone marrow cells positive for terminal deoxynucleotidyl transferase (TdT), HLA-DR, and a T cell marker may represent prothymocytes.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(5):3144-50.
1985: Jacques J M van Dongen; Herbert Hooijkaas; W Marieke Comans-Bitter; K Benne; T M Van Os; J De Josselin de Jong
Triple immunological staining with colloidal gold, fluorescein and rhodamine as labels.
Journal of immunological methods 1985;80(1):1-6.
1985: Jacques J M van Dongen; Herbert Hooijkaas; W Marieke Comans-Bitter; Karel Hählen; G E van Zanen
The small subpopulation of T cell marker+/TdT+ cells in the human bone marrow may represent prothymocytes.
Advances in experimental medicine and biology 1985;186():889-99.
1984: Herbert Hooijkaas; Jacques J M van Dongen; Karel Hählen; G E van Zanen
Immunological characterisation of cells in cerebrospinal fluid from patients with lymphoid malignancies.
Lancet 1984;1(8375):518-9.