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Jacques van Dongen

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
van der Burg Mirjam; Ijspeert Hanna; Verkaik Nicole S; Turul Tuba; Wiegant Wouter W; Morotomi-Yano Keiko; Mari Pierre-Olivier; Tezcan Ilhan; Chen David J; Zdzienicka Malgorzata Z; van Dongen Jacques J M; van Gent Dik C
A DNA-PKcs mutation in a radiosensitive T-B- SCID patient inhibits Artemis activation and nonhomologous end-joining.
Luis Tiago C; Weerkamp Floor; Naber Brigitta A E; Baert Miranda R M; de Haas Edwin F E; Nikolic Tatjana; Heuvelmans Sjanneke; De Krijger Ronald R; van Dongen Jacques J M; Staal Frank J T
Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation.
Turul Tuba; Tezcan Ilhan; Artac Hasibe; de Bruin-Versteeg Sandra; Barendregt Barbara H; Reisli Ismail; Sanal Ozden; van Dongen Jacques J M; van der Burg Mirjam
Clinical heterogeneity can hamper the diagnosis of patients with ZAP70 deficiency.

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All Publications

2009: van der Burg Mirjam; Ijspeert Hanna; Verkaik Nicole S; Turul Tuba; Wiegant Wouter W; Morotomi-Yano Keiko; Mari Pierre-Olivier; Tezcan Ilhan; Chen David J; Zdzienicka Malgorzata Z; van Dongen Jacques J M; van Gent Dik C
A DNA-PKcs mutation in a radiosensitive T-B- SCID patient inhibits Artemis activation and nonhomologous end-joining.
The Journal of clinical investigation 2009;119(1):91-8.
2009: Luis Tiago C; Weerkamp Floor; Naber Brigitta A E; Baert Miranda R M; de Haas Edwin F E; Nikolic Tatjana; Heuvelmans Sjanneke; De Krijger Ronald R; van Dongen Jacques J M; Staal Frank J T
Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation.
Blood 2009;113(3):546-54.
2009: Turul Tuba; Tezcan Ilhan; Artac Hasibe; de Bruin-Versteeg Sandra; Barendregt Barbara H; Reisli Ismail; Sanal Ozden; van Dongen Jacques J M; van der Burg Mirjam
Clinical heterogeneity can hamper the diagnosis of patients with ZAP70 deficiency.
European journal of pediatrics 2009;168(1):87-93.
2009: Duijts Liesbeth; Bakker-Jonges Liesbeth E; Mook-Kanamori Dennis O; Labout Joost A M; Hofman Albert; van Duijn Cornelia M; van Dongen Jacques J M; Hooijkaas Herbert; Moll Henriëtte A; Jaddoe Vincent W V
Variation in the IGF-1 gene is associated with lymphocyte subset counts in neonates: the Generation R Study.
Clinical endocrinology 2009;70(1):53-9.
2009: van der Burg Mirjam; van Zelm Menno C; van Dongen Jacques J M
Molecular diagnostics of primary immunodeficiencies: benefits and future challenges.
Advances in experimental medicine and biology 2009;634():231-41.
2009: van der Velden Vincent H J; van Dongen Jacques J M
MRD detection in acute lymphoblastic leukemia patients using Ig/TCR gene rearrangements as targets for real-time quantitative PCR.
Methods in molecular biology (Clifton, N.J.) 2009;538():115-50.
2009: Duijts Liesbeth; Bakker-Jonges Liesbeth E; Labout Joost A M; Jaddoe Vincent W V; Hofman Albert; Steegers Eric A P; van Dongen Jacques J M; Hooijkaas Herbert; Moll Henriëtte A
Fetal growth influences lymphocyte subset counts at birth: the Generation R Study.
Neonatology 2009;95(2):149-56.
2008: Staal F J T; Pike-Overzet K; Ng Y Y; van Dongen J J M
Sola dosis facit venenum. Leukemia in gene therapy trials: a question of vectors, inserts and dosage?
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2008;22(10):1849-52.
2008: Groenen Patricia J T A; Langerak Anton W; van Dongen Jacques J M; van Krieken Johan H J M
Pitfalls in TCR gene clonality testing: teaching cases.
Journal of hematopathology 2008;1(2):97-109.
2008: Pedreira Carlos E; Costa Elaine S; Barrena Susana; Lecrevisse Quentin; Almeida Julia; van Dongen Jacques J M; Orfao Alberto;
Generation of flow cytometry data files with a potentially infinite number of dimensions.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2008;73(9):834-46.
2008: Jhunjhunwala Suchit; van Zelm Menno C; Peak Mandy M; Cutchin Steve; Riblet Roy; van Dongen Jacques J M; Grosveld Frank G; Knoch Tobias A; Murre Cornelis
The 3D structure of the immunoglobulin heavy-chain locus: implications for long-range genomic interactions.
Cell 2008;133(2):265-79.
2008: Duijts Liesbeth; Bakker-Jonges Liesbeth E; Labout Joost A M; Jaddoe Vincent W V; Hofman Albert; Steegers Eric A P; Van Dongen Jacques J M; Hooijkaas Herbert; Moll Henriëtte A
Perinatal stress influences lymphocyte subset counts in neonates. The generation R study.
Pediatric research 2008;63(3):292-8.
2008: van Zelm Menno C; Geertsema Corinne; Nieuwenhuis Nicole; de Ridder Dick; Conley Mary Ellen; Schiff Claudine; Tezcan Ilhan; Bernatowska Ewa; Hartwig Nico G; Sanders Elisabeth A M; Litzman Jiri; Kondratenko Irina; van Dongen Jacques J M; van der Burg Mirjam
Gross deletions involving IGHM, BTK, or Artemis: a model for genomic lesions mediated by transposable elements.
American journal of human genetics 2008;82(2):320-32.
2007: van Zelm Menno C; van der Burg Mirjam; van Dongen Jacques J M
Homeostatic and maturation-associated proliferation in the peripheral B-cell compartment.
Cell cycle (Georgetown, Tex.) 2007;6(23):2890-5.
2007: Pike-Overzet Karin; van der Burg Mirjam; Wagemaker Gerard; van Dongen Jacques J M; Staal Frank J T
New insights and unresolved issues regarding insertional mutagenesis in X-linked SCID gene therapy.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(11):1910-6.
2007: González David; van der Burg Mirjam; García-Sanz Ramón; Fenton James A; Langerak Anton W; González Marcos; van Dongen Jacques J M; San Miguel Jesus F; Morgan Gareth J
Immunoglobulin gene rearrangements and the pathogenesis of multiple myeloma.
Blood 2007;110(9):3112-21.
2007: Noordzij Jeroen G; Hartwig Nico G; Verreck Frank A W; De Bruin-Versteeg Sandra; De Boer Tjitske; Van Dissel Jaap T; De Groot Ronald; Ottenhoff Tom H M; Van Dongen Jacques J M
Two patients with complete defects in interferon gamma receptor-dependent signaling.
Journal of clinical immunology 2007;27(5):490-6.
2007: Boudewijns Michaël; van Dongen Jacques J M; Langerak Anton W
The human androgen receptor X-chromosome inactivation assay for clonality diagnostics of natural killer cell proliferations.
The Journal of molecular diagnostics : JMD 2007;9(3):337-44.
2007: Zuna J; Cavé H; Eckert C; Szczepanski T; Meyer C; Mejstrikova E; Fronkova E; Muzikova K; Clappier E; Mendelova D; Boutard P; Schrauder A; Sterba J; Marschalek R; van Dongen J J M; Hrusak O; Stary J; Trka J
Childhood secondary ALL after ALL treatment.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(7):1431-5.
2007: Dik Willem A; Nadel Bertrand; Przybylski Grzegorz K; Asnafi Vahid; Grabarczyk Piotr; Navarro Jean Marc; Verhaaf Brenda; Schmidt Christian A; Macintyre Elizabeth A; van Dongen Jacques J M; Langerak Anton W
Different chromosomal breakpoints impact the level of LMO2 expression in T-ALL.
Blood 2007;110(1):388-92.
2007: Walter Roland B; Gooley Ted A; van der Velden Vincent H J; Loken Michael R; van Dongen Jacques J M; Flowers David A; Bernstein Irwin D; Appelbaum Frederick R
CD33 expression and P-glycoprotein-mediated drug efflux inversely correlate and predict clinical outcome in patients with acute myeloid leukemia treated with gemtuzumab ozogamicin monotherapy.
Blood 2007;109(10):4168-70.
2007: van der Velden V H J; Panzer-Grümayer E R; Cazzaniga G; Flohr T; Sutton R; Schrauder A; Basso G; Schrappe M; Wijkhuijs J M; Konrad M; Bartram C R; Masera G; Biondi A; van Dongen J J M
Optimization of PCR-based minimal residual disease diagnostics for childhood acute lymphoblastic leukemia in a multi-center setting.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(4):706-13.
2007: van der Velden V H J; Cazzaniga G; Schrauder A; Hancock J; Bader P; Panzer-Grumayer E R; Flohr T; Sutton R; Cave H; Madsen H O; Cayuela J M; Trka J; Eckert C; Foroni L; Zur Stadt U; Beldjord K; Raff T; van der Schoot C E; van Dongen J J M;
Analysis of minimal residual disease by Ig/TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(4):604-11.
2007: Pike-Overzet K; de Ridder D; Weerkamp F; Baert M R M; Verstegen M M A; Brugman M H; Howe S J; Reinders M J T; Thrasher A J; Wagemaker G; van Dongen J J M; Staal F J T
Ectopic retroviral expression of LMO2, but not IL2Rgamma, blocks human T-cell development from CD34+ cells: implications for leukemogenesis in gene therapy.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(4):754-63.
2007: Jansen M W J C; Corral L; van der Velden V H J; Panzer-Grümayer R; Schrappe M; Schrauder A; Marschalek R; Meyer C; den Boer M L; Hop W J C; Valsecchi M G; Basso G; Biondi A; Pieters R; van Dongen J J M
Immunobiological diversity in infant acute lymphoblastic leukemia is related to the occurrence and type of MLL gene rearrangement.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(4):633-41.
2007: van Zelm Menno C; Szczepanski Tomasz; van der Burg Mirjam; van Dongen Jacques J M
Replication history of B lymphocytes reveals homeostatic proliferation and extensive antigen-induced B cell expansion.
The Journal of experimental medicine 2007;204(3):645-55.
2007: Brüggemann M; White H; Gaulard P; Garcia-Sanz R; Gameiro P; Oeschger S; Jasani B; Ott M; Delsol G; Orfao A; Tiemann M; Herbst H; Langerak A W; Spaargaren M; Moreau E; Groenen P J T A; Sambade C; Foroni L; Carter G I; Hummel M; Bastard C; Davi F; Delfau-Larue M-H; Kneba M; van Dongen J J M; Beldjord K; Molina T J
Powerful strategy for polymerase chain reaction-based clonality assessment in T-cell malignancies Report of the BIOMED-2 Concerted Action BHM4 CT98-3936.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(2):215-21.
2007: Langerak A W; Molina T J; Lavender F L; Pearson D; Flohr T; Sambade C; Schuuring E; Al Saati T; van Dongen J J M; van Krieken J H J M
Polymerase chain reaction-based clonality testing in tissue samples with reactive lymphoproliferations: usefulness and pitfalls. A report of the BIOMED-2 Concerted Action BMH4-CT98-3936.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(2):222-9.
2007: Sandberg Y; Verhaaf B; van Gastel-Mol E J; Wolvers-Tettero I L M; de Vos J; Macleod R A F; Noordzij J G; Dik W A; van Dongen J J M; Langerak A W
Human T-cell lines with well-defined T-cell receptor gene rearrangements as controls for the BIOMED-2 multiplex polymerase chain reaction tubes.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(2):230-7.
2007: Darroudi Firouz; Wiegant Wouter; Meijers Matty; Friedl Anna A; van der Burg Mirjam; Fomina Janna; van Dongen Jacques J M; van Gent Dik C; Zdzienicka Malgorzata Z
Role of Artemis in DSB repair and guarding chromosomal stability following exposure to ionizing radiation at different stages of cell cycle.
Mutation research 2007;615(1-2):111-24.
2006: van der Burg Mirjam; Weemaes Corry M R; Preijers Frank; Brons Paul; Barendregt Barbara H; van Tol Maarten J D; Hoogerbrugge Peter; van Dongen Jacques J M
B-cell recovery after stem cell transplantation of Artemis-deficient SCID requires elimination of autologous bone marrow precursor-B-cells.
Haematologica 2006;91(12):1705-9.
2006: Sandberg Y; Dezentjé V O; Szuhai K; van Houte A J; Tielemans D; Wolvers-Tettero I L M; van Dongen J J M; van der Griend R; Langerak A W
Clonal T- and natural killer-cell large granular lymphocyte proliferations in a single patient established by array-based comparative genomic hybridization analysis.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(12):2212-4.
2006: Weerkamp F; Luis T C; Naber B A E; Koster E E L; Jeannotte L; van Dongen J J M; Staal F J T
Identification of Notch target genes in uncommitted T-cell progenitors: No direct induction of a T-cell specific gene program.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(11):1967-77.
2006: Pike-Overzet Karin; de Ridder Dick; Weerkamp Floor; Baert Miranda R M; Verstegen Monique M; Brugman Martijn H; Howe Steven J; Reinders Marcel J T; Thrasher Adrian J; Wagemaker Gerard; van Dongen Jacques J M; Staal Frank J T
Gene therapy: is IL2RG oncogenic in T-cell development?
Nature 2006;443(7109):E5; discussion E6-7.
2006: Staal F J T; Cario G; Cazzaniga G; Haferlach T; Heuser M; Hofmann W-K; Mills K; Schrappe M; Stanulla M; Wingen L U; van Dongen J J M; Schlegelberger B
Consensus guidelines for microarray gene expression analyses in leukemia from three European leukemia networks.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(8):1385-92.
2006: Weerkamp F; van Dongen J J M; Staal F J T
Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(7):1197-205.
2006: van Zelm Menno C; Reisli Ismail; van der Burg Mirjam; Castaño Diana; van Noesel Carel J M; van Tol Maarten J D; Woellner Cristina; Grimbacher Bodo; Patiño Pablo J; van Dongen Jacques J M; Franco José L
An antibody-deficiency syndrome due to mutations in the CD19 gene.
The New England journal of medicine 2006;354(18):1901-12.
2006: van der Velden Vincent H J; Hoogeveen Patricia G; Pieters Rob; van Dongen Jacques J M
Impact of two independent bone marrow samples on minimal residual disease monitoring in childhood acute lymphoblastic leukaemia.
British journal of haematology 2006;133(4):382-8.
2006: van der Velden Vincent H J; de Bie Maaike; van Wering Elisabeth R; van Dongen Jacques J M
Immunoglobulin light chain gene rearrangements in precursor-B-acute lymphoblastic leukemia: characteristics and applicability for the detection of minimal residual disease.
Haematologica 2006;91(5):679-82.
2006: Neves Hélia; Weerkamp Floor; Gomes Andreia C; Naber Brigitta A E; Gameiro Paula; Becker Jörg D; Lúcio Paulo; Clode Nuno; van Dongen Jacques J M; Staal Frank J T; Parreira Leonor
Effects of Delta1 and Jagged1 on early human hematopoiesis: correlation with expression of notch signaling-related genes in CD34+ cells.
Stem cells (Dayton, Ohio) 2006;24(5):1328-37.
2006: Warnatz Klaus; Bossaller Lukas; Salzer Ulrich; Skrabl-Baumgartner Andrea; Schwinger Wolfgang; van der Burg Mirjam; van Dongen Jacques J M; Orlowska-Volk Marzena; Knoth Rolf; Durandy Anne; Draeger Ruth; Schlesier Michael; Peter Hans Hartmut; Grimbacher Bodo
Human ICOS deficiency abrogates the germinal center reaction and provides a monogenic model for common variable immunodeficiency.
Blood 2006;107(8):3045-52.
2006: Weerkamp Floor; Baert Miranda R M; Brugman Martijn H; Dik Willem A; de Haas Edwin F E; Visser Trudi P; de Groot Christianne J M; Wagemaker Gerard; van Dongen Jacques J M; Staal Frank J T
Human thymus contains multipotent progenitors with T/B lymphoid, myeloid, and erythroid lineage potential.
Blood 2006;107(8):3131-7.
2006: Przybylski Grzegorz K; Dik Willem A; Grabarczyk Piotr; Wanzeck Jens; Chudobska Paulina; Jankowski Kacper; von Bergh Anne; van Dongen Jacques J M; Schmidt Christian A; Langerak Anton W
The effect of a novel recombination between the homeobox gene NKX2-5 and the TRD locus in T-cell acute lymphoblastic leukemia on activation of the NKX2-5 gene.
Haematologica 2006;91(3):317-21.
2006: Sandberg Y; Almeida J; Gonzalez M; Lima M; Bárcena P; Szczepañski T; van Gastel-Mol E J; Wind H; Balanzategui A; van Dongen J J M; Miguel J F San; Orfao A; Langerak A W
TCRgammadelta+ large granular lymphocyte leukemias reflect the spectrum of normal antigen-selected TCRgammadelta+ T-cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(3):505-13.
2006: Weerkamp Floor; Baert Miranda R M; Naber Brigitta A E; Koster Esther E L; de Haas Edwin F E; Atkuri Kondala R; van Dongen Jacques J M; Herzenberg Leonard A; Staal Frank J T
Wnt signaling in the thymus is regulated by differential expression of intracellular signaling molecules.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(9):3322-6.
2006: de Ridder Dick; Staal Frank J T; van Dongen Jacques J M; Reinders Marcel J T
Maximum significance clustering of oligonucleotide microarrays.
Bioinformatics (Oxford, England) 2006;22(3):326-31.
2006: van der Burg Mirjam; van Veelen Lieneke R; Verkaik Nicole S; Wiegant Wouter W; Hartwig Nico G; Barendregt Barbara H; Brugmans Linda; Raams Anja; Jaspers Nicolaas G J; Zdzienicka Malgorzata Z; van Dongen Jacques J M; van Gent Dik C
A new type of radiosensitive T-B-NK+ severe combined immunodeficiency caused by a LIG4 mutation.
The Journal of clinical investigation 2006;116(1):137-45.
2006: Yang Yang; Takeuchi Seisho; Hofmann Wolf K; Ikezoe Takayuki; van Dongen Jacques J M; Szczepanski Tomasz; Bartram Claus R; Yoshino Norihide; Taguchi Hirokuni; Koeffler H Phillip
Aberrant methylation in promoter-associated CpG islands of multiple genes in acute lymphoblastic leukemia.
Leukemia research 2006;30(1):98-102.
2006: Szczepanski Tomasz; van der Velden Vincent H J; van Dongen Jacques J M
Flow-cytometric immunophenotyping of normal and malignant lymphocytes.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2006;44(7):775-96.
2006: Langerak Anton W; van Dongen Jacques J M
Recombination in the human IGK locus.
Critical reviews in immunology 2006;26(1):23-42.
2005: Panzer-Grümayer E Renate; Cazzaniga Giovanni; van der Velden Vincent H J; del Giudice Laura; Peham Martina; Mann Georg; Eckert Conny; Schrauder Andre; Germano Giuseppe; Harbott Jochen; Basso Giuseppe; Biondi Andrea; van Dongen Jacques J M; Gadner Helmut; Haas Oskar A
Immunogenotype changes prevail in relapses of young children with TEL-AML1-positive acute lymphoblastic leukemia and derive mainly from clonal selection.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(21):7720-7.
2005: van Zelm Menno C; van der Burg Mirjam; de Ridder Dick; Barendregt Barbara H; de Haas Edwin F E; Reinders Marcel J T; Lankester Arjan C; Révész Tom; Staal Frank J T; van Dongen Jacques J M
Ig gene rearrangement steps are initiated in early human precursor B cell subsets and correlate with specific transcription factor expression.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(9):5912-22.
2005: Boeckx N; De Roover J; van der Velden V H J; Maertens J; Uyttebroeck A; Vandenberghe P; van Dongen J J M
Quantification of CBFB-MYH11 fusion gene levels in paired peripheral blood and bone marrow samples by real-time PCR.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(11):1988-90.
2005: Jansen M W J C; van der Velden V H J; van Dongen J J M
Efficient and easy detection of MLL-AF4, MLL-AF9 and MLL-ENL fusion gene transcripts by multiplex real-time quantitative RT-PCR in TaqMan and LightCycler.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(11):2016-8.
2005: Dik W A; Brahim W; Braun C; Asnafi V; Dastugue N; Bernard O A; van Dongen J J M; Langerak A W; Macintyre E A; Delabesse E
CALM-AF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(11):1948-57.
2005: Sandberg Yorick; van Gastel-Mol Ellen J; Verhaaf Brenda; Lam King H; van Dongen Jacques J M; Langerak Anton W
BIOMED-2 multiplex immunoglobulin/T-cell receptor polymerase chain reaction protocols can reliably replace Southern blot analysis in routine clonality diagnostics.
The Journal of molecular diagnostics : JMD 2005;7(4):495-503.
2005: Larson Richard A; Sievers Eric L; Stadtmauer Edward A; Löwenberg Bob; Estey Elihu H; Dombret Hervé; Theobald Matthias; Voliotis Dimitris; Bennett John M; Richie Maria; Leopold Lance H; Berger Mark S; Sherman Matthew L; Loken Michael R; van Dongen Jacques J M; Bernstein Irwin D; Appelbaum Frederick R
Final report of the efficacy and safety of gemtuzumab ozogamicin (Mylotarg) in patients with CD33-positive acute myeloid leukemia in first recurrence.
Cancer 2005;104(7):1442-52.
2005: Boeckx N; Jansen M W J C; Haskovec C; Vandenberghe P; van der Velden V H J; van Dongen J J M
Identification of e19a2 BCR-ABL fusions (mu-BCR breakpoints) at the DNA level by ligation-mediated PCR.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(7):1292-5.
2005: Dik Willem A; Pike-Overzet Karin; Weerkamp Floor; de Ridder Dick; de Haas Edwin F E; Baert Miranda R M; van der Spek Peter; Koster Esther E L; Reinders Marcel J T; van Dongen Jacques J M; Langerak Anton W; Staal Frank J T
New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling.
The Journal of experimental medicine 2005;201(11):1715-23.
2005: Weerkamp Floor; de Haas Edwin F E; Naber Brigitta A E; Comans-Bitter W Marieke; Bogers Ad J J C; van Dongen Jacques J M; Staal Frank J T
Age-related changes in the cellular composition of the thymus in children.
The Journal of allergy and clinical immunology 2005;115(4):834-40.
2005: de Ridder D; van der Linden C E; Schonewille T; Dik W A; Reinders M J T; van Dongen J J M; Staal F J T
Purity for clarity: the need for purification of tumor cells in DNA microarray studies.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(4):618-27.
2005: Przybylski G K; Dik W A; Wanzeck J; Grabarczyk P; Majunke S; Martin-Subero J I; Siebert R; Dölken G; Ludwig W-D; Verhaaf B; van Dongen J J M; Schmidt C A; Langerak A W
Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(2):201-8.
2005: Meyer Claus; Schneider Bjoern; Reichel Martin; Angermueller Sieglinde; Strehl Sabine; Schnittger Susanne; Schoch Claudia; Jansen Mieke W J C; van Dongen Jacques J; Pieters Rob; Haas Oskar A; Dingermann Theo; Klingebiel Thomas; Marschalek Rolf
Diagnostic tool for the identification of MLL rearrangements including unknown partner genes.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(2):449-54.
2005: van Dongen J J M; van der Burg M; Langerak A W
Split-signal FISH for detection of chromosome aberrations.
Hematology (Amsterdam, Netherlands) 2005;10 Suppl 1():66-72.
2004: van der Velden V H J; Brüggemann M; Hoogeveen P G; de Bie M; Hart P G; Raff T; Pfeifer H; Lüschen S; Szczepanski T; van Wering E R; Kneba M; van Dongen J J M
TCRB gene rearrangements in childhood and adult precursor-B-ALL: frequency, applicability as MRD-PCR target, and stability between diagnosis and relapse.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004;18(12):1971-80.
2004: Levelink Birgit; de Vries Esther; van Dissel Jaap T; van Dongen Jacques J M
Pulmonary mycobacterium avium intracellulare infection in an immunocompetent child.
The Pediatric infectious disease journal 2004;23(9):892.
2004: Langerak Anton W; Nadel Bertrand; De Torbal Anneke; Wolvers-Tettero Ingrid L M; van Gastel-Mol Ellen J; Verhaaf Brenda; Jäger Ulrich; van Dongen Jacques J M
Unraveling the consecutive recombination events in the human IGK locus.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(6):3878-88.
2004: Droese J; Langerak A W; Groenen P J T A; Brüggemann M; Neumann P; Wolvers-Tettero I L M; van Altena M C; Kneba M; van Dongen J J M
Validation of BIOMED-2 multiplex PCR tubes for detection of TCRB gene rearrangements in T-cell malignancies.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004;18(9):1531-8.
2004: Boeckx Nancy; van der Velden Vincent H J; Boogaerts Marc; Hagemeijer Anne; Vandenberghe Peter; van Dongen Jacques J M
An inv(16)(p13q22) positive acute myeloid leukaemia relapsing as acute precursor B-cell lymphoblastic leukaemia.
Haematologica 2004;89(8):ECR28.
2004: van Lochem E G; van der Velden V H J; Wind H K; te Marvelde J G; Westerdaal N A C; van Dongen J J M
Immunophenotypic differentiation patterns of normal hematopoiesis in human bone marrow: reference patterns for age-related changes and disease-induced shifts.
Cytometry. Part B, Clinical cytometry 2004;60(1):1-13.
2004: Matsushita Chise; Yang Yang; Takeuchi Seisho; Matsushita Masahide; Van Dongen Jacques J M; Szczepanski Tomasz; Bartram Claus R; Seo Hiromi; Koeffler H Phillip; Taguchi Hirokuni
Aberrant methylation in promoter-associated CpG islands of multiple genes in relapsed childhood acute lymphoblastic leukemia.
Oncology reports 2004;12(1):97-9.
2004: van Zutven Laura J C M; Velthuizen Sandra C J M; Wolvers-Tettero Ingrid L M; van Dongen Jacques J M; Poulsen Tim S; MacLeod Roderick A F; Beverloo H Berna; Langerak Anton W
Two dual-color split signal fluorescence in situ hybridization assays to detect t(5;14) involving HOX11L2 or CSX in T-cell acute lymphoblastic leukemia.
Haematologica 2004;89(6):671-8.
2004: Jansen A G; Noordzij J G; Bröcker-Vriends A H; van Dongen J J; van Tol M J; Bredius R G
[Widely divergent clinical phenotype of x-linked agammaglobulinemia in two cousins]
Nederlands tijdschrift voor geneeskunde 2004;148(21):1053-6.
2004: van der Burg M; Poulsen T S; Hunger S P; Beverloo H B; Smit E M E; Vang-Nielsen K; Langerak A W; van Dongen J J M
Split-signal FISH for detection of chromosome aberrations in acute lymphoblastic leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004;18(5):895-908.
2004: van der Velden V H J; Boeckx N; Jedema I; te Marvelde J G; Hoogeveen P G; Boogaerts M; van Dongen J J M
High CD33-antigen loads in peripheral blood limit the efficacy of gemtuzumab ozogamicin (Mylotarg) treatment in acute myeloid leukemia patients.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004;18(5):983-8.
2004: Szczepanski Tomasz; van der Velden Vincent H J; Hoogeveen Patricia G; de Bie Maaike; Jacobs Daniëlle C H; van Wering Elisabeth R; van Dongen Jacques J M
Vdelta2-Jalpha rearrangements are frequent in precursor-B-acute lymphoblastic leukemia but rare in normal lymphoid cells.
Blood 2004;103(10):3798-804.
2004: van der Velden V H J; Boeckx N; van Wering E R; van Dongen J J M
Detection of minimal residual disease in acute leukemia.
Journal of biological regulators and homeostatic agents 2004;18(2):146-54.
2004: Szczepanski Tomasz; de Vaan Gerard A M; Beishuizen Auke; Bogman José; Jansen Mieke W J C; van Wering Elisabeth R; van Dongen Jacques J M
Acute lymphoblastic leukemia followed by a clonally-unrelated EBV-positive non-Hodgkin lymphoma and a clonally-related myelomonocytic leukemia cutis.
Pediatric blood & cancer 2004;42(4):343-9.
2004: Brüggemann M; van der Velden V H J; Raff T; Droese J; Ritgen M; Pott C; Wijkhuijs A J; Gökbuget N; Hoelzer D; van Wering E R; van Dongen J J M; Kneba M
Rearranged T-cell receptor beta genes represent powerful targets for quantification of minimal residual disease in childhood and adult T-cell acute lymphoblastic leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004;18(4):709-19.
2004: van der Velden V H J; Boeckx N; Gonzalez M; Malec M; Barbany G; Lion T; Gottardi E; Pallisgaard N; Beillard E; Hop W C J; Hoogeveen P G; Gabert J; van Dongen J J M;
Differential stability of control gene and fusion gene transcripts over time may hamper accurate quantification of minimal residual disease--a study within the Europe Against Cancer Program.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004;18(4):884-6.
2004: Jedema I; Barge R M Y; van der Velden V H J; Nijmeijer B A; van Dongen J J M; Willemze R; Falkenburg J H F
Internalization and cell cycle-dependent killing of leukemic cells by Gemtuzumab Ozogamicin: rationale for efficacy in CD33-negative malignancies with endocytic capacity.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004;18(2):316-25.
2004: Staal Frank J T; Weerkamp Floor; Baert Miranda R M; van den Burg Caroline M M; van Noort Mascha; de Haas Edwin F E; van Dongen Jacques J M
Wnt target genes identified by DNA microarrays in immature CD34+ thymocytes regulate proliferation and cell adhesion.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(2):1099-108.
2003: van Dongen J J M; Langerak A W; Brüggemann M; Evans P A S; Hummel M; Lavender F L; Delabesse E; Davi F; Schuuring E; García-Sanz R; van Krieken J H J M; Droese J; González D; Bastard C; White H E; Spaargaren M; González M; Parreira A; Smith J L; Morgan G J; Kneba M; Macintyre E A
Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(12):2257-317.
2003: Szczepanski Tomasz; van der Velden Vincent H J; van Dongen Jacques J M
Classification systems for acute and chronic leukaemias.
Best practice & research. Clinical haematology 2003;16(4):561-82.
2003: Gabert J; Beillard E; van der Velden V H J; Bi W; Grimwade D; Pallisgaard N; Barbany G; Cazzaniga G; Cayuela J M; Cavé H; Pane F; Aerts J L E; De Micheli D; Thirion X; Pradel V; González M; Viehmann S; Malec M; Saglio G; van Dongen J J M
Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(12):2318-57.
2003: Beillard E; Pallisgaard N; van der Velden V H J; Bi W; Dee R; van der Schoot E; Delabesse E; Macintyre E; Gottardi E; Saglio G; Watzinger F; Lion T; van Dongen J J M; Hokland P; Gabert J
Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time' quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR) - a Europe against cancer program.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(12):2474-86.
2003: Langerak Anton W; Sandberg Yorick; van Dongen Jacques J M
Spectrum of T-large granular lymphocyte lymphoproliferations: ranging from expanded activated effector T cells to T-cell leukaemia.
British journal of haematology 2003;123(3):561-2.
2003: Szczepanski T; van der Velden V H J; Raff T; Jacobs D C H; van Wering E R; Brüggemann M; Kneba M; van Dongen J J M
Comparative analysis of T-cell receptor gene rearrangements at diagnosis and relapse of T-cell acute lymphoblastic leukemia (T-ALL) shows high stability of clonal markers for monitoring of minimal residual disease and reveals the occurrence of second T-ALL.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(11):2149-56.
2003: Takeuchi Seisho; Seriu Taku; van Dongen Jacques J M; Szczepanski Tomasz; Tsukasaki Kunihiro; Takeuchi Naoko; Fermin Anthony C; Seo Hiromi; Bartram Claus R; Koeffler H Phillip
Allelotype analysis in relapsed childhood acute lymphoblastic leukemia.
Oncogene 2003;22(44):6970-6.
2003: Krejci O; van der Velden V H J; Bader P; Kreyenberg H; Goulden N; Hancock J; Schilham M W; Lankester A; Révész T; Klingebiel T; van Dongen J J M
Level of minimal residual disease prior to haematopoietic stem cell transplantation predicts prognosis in paediatric patients with acute lymphoblastic leukaemia: a report of the Pre-BMT MRD Study Group.
Bone marrow transplantation 2003;32(8):849-51.
2003: van der Velden V H J; Szczepanski T; Wijkhuijs J M; Hart P G; Hoogeveen P G; Hop W C J; van Wering E R; van Dongen J J M
Age-related patterns of immunoglobulin and T-cell receptor gene rearrangements in precursor-B-ALL: implications for detection of minimal residual disease.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(9):1834-44.
2003: Staal F J T; van der Burg M; Wessels L F A; Barendregt B H; Baert M R M; van den Burg C M M; van Huffel C; Langerak A W; van der Velden V H J; Reinders M J T; van Dongen J J M
DNA microarrays for comparison of gene expression profiles between diagnosis and relapse in precursor-B acute lymphoblastic leukemia: choice of technique and purification influence the identification of potential diagnostic markers.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(7):1324-32.
2003: Sandberg Yorick; Heule Freerk; Lam King; Lugtenburg Pieternella J; Wolvers-Tettero Ingrid L M; van Dongen Jacques J M; Langerak Anton W
Molecular immunoglobulin/T- cell receptor clonality analysis in cutaneous lymphoproliferations. Experience with the BIOMED-2 standardized polymerase chain reaction protocol.
Haematologica 2003;88(6):659-70.
2003: van der Velden V H J; Hochhaus A; Cazzaniga G; Szczepanski T; Gabert J; van Dongen J J M
Detection of minimal residual disease in hematologic malignancies by real-time quantitative PCR: principles, approaches, and laboratory aspects.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(6):1013-34.
2003: van Krieken J H J M; Langerak A W; San Miguel J F; Parreira A; Smith J L; Morgan G M; Kneba M; Macintyre E A; van Dongen J J M
Clonality analysis for antigen receptor genes: preliminary results from the Biomed-2 concerted action PL 96-3936.
Human pathology 2003;34(4):359-61.
2003: Noordzij Jeroen G; Verkaik Nicole S; van der Burg Mirjam; van Veelen Lieneke R; de Bruin-Versteeg Sandra; Wiegant Wouter; Vossen Jaak M J J; Weemaes Corry M R; de Groot Ronald; Zdzienicka Malgorzata Z; van Gent Dik C; van Dongen Jacques J M
Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre-B-cell receptor checkpoint in bone marrow.
Blood 2003;101(4):1446-52.
2003: Moppett J; van der Velden V H J; Wijkhuijs A J M; Hancock J; van Dongen J J M; Goulden N
Inhibition affecting RQ-PCR-based assessment of minimal residual disease in acute lymphoblastic leukemia: reversal by addition of bovine serum albumin.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(1):268-70.
2003: Przybylski Grzegorz K; Wanzeck Jens; Verschuren Martie C M; Van Dongen Jacques J M; Serke Stephan; Schmidt Christian A
Identification of a new cluster of T-cell receptor delta recombining elements.
Immunology 2003;108(1):16-23.
2002: Noordzij Jeroen G; de Bruin-Versteeg Sandra; Hartwig Nico G; Weemaes Corry M R; Gerritsen Egbert J A; Bernatowska Eva; van Lierde Stefaan; de Groot Ronald; van Dongen Jacques J M
XLA patients with BTK splice-site mutations produce low levels of wild-type BTK transcripts.
Journal of clinical immunology 2002;22(5):306-18.
2002: Larson R A; Boogaerts M; Estey E; Karanes C; Stadtmauer E A; Sievers E L; Mineur P; Bennett J M; Berger M S; Eten C B; Munteanu M; Loken M R; Van Dongen J J M; Bernstein I D; Appelbaum F R;
Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin).
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(9):1627-36.
2002: Noordzij Jeroen G; de Bruin-Versteeg Sandra; Verkaik Nicole S; Vossen Jaak M J J; de Groot Ronald; Bernatowska Ewa; Langerak Anton W; van Gent Dik C; van Dongen Jacques J M
The immunophenotypic and immunogenotypic B-cell differentiation arrest in bone marrow of RAG-deficient SCID patients corresponds to residual recombination activities of mutated RAG proteins.
Blood 2002;100(6):2145-52.
2002: Langerak A W; Moreau E; van Gastel-Mol E J; van der Burg M; van Dongen J J M
Detection of clonal EBV episomes in lymphoproliferations as a diagnostic tool.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(8):1572-3.
2002: van der Burg M; Barendregt B H; Szczepañski T; van Wering E R; Langerak A W; van Dongen J J M
Immunoglobulin light chain gene rearrangements display hierarchy in absence of selection for functionality in precursor-B-ALL.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(8):1448-53.
2002: van der Velden V H J; Jacobs D C H; Wijkhuijs A J M; Comans-Bitter W M; Willemse M J; Hählen K; Kamps W A; van Wering E R; van Dongen J J M
Minimal residual disease levels in bone marrow and peripheral blood are comparable in children with T cell acute lymphoblastic leukemia (ALL), but not in precursor-B-ALL.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(8):1432-6.
2002: Broers Annoek E C; Meijerink Jules P P; van Dongen Jacques J M; Posthumus Sandra J; Löwenberg Bob; Braakman Eric; Cornelissen Jan J
Quantification of newly developed T cells in mice by real-time quantitative PCR of T-cell receptor rearrangement excision circles.
Experimental hematology 2002;30(7):745-50.
2002: van der Velden V H J; Wijkhuijs J M; Jacobs D C H; van Wering E R; van Dongen J J M
T cell receptor gamma gene rearrangements as targets for detection of minimal residual disease in acute lymphoblastic leukemia by real-time quantitative PCR analysis.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(7):1372-80.
2002: van der Burg M; Bende R J; Aarts W M; Langerak A W; van Dongen J J M; van Noesel C J M
Biased Iglambda expression in hypermutated IgD multiple myelomas does not result from receptor revision.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(7):1358-61.
2002: van der Burg Mirjam; Barendregt Barbara H; van Gastel-Mol Ellen J; Tümkaya Talip; Langerak Anton W; van Dongen Jacques J M
Unraveling of the polymorphic C lambda 2-C lambda 3 amplification and the Ke+Oz- polymorphism in the human Ig lambda locus.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(1):271-6.
2002: Willemse Marja J; Seriu Taku; Hettinger Klaudia; d'Aniello Elisabetta; Hop Wim C J; Panzer-Grümayer E Renate; Biondi Andrea; Schrappe Martin; Kamps Willem A; Masera Guiseppe; Gadner Helmut; Riehm Hansjoerg; Bartram Claus R; van Dongen Jacques J M
Detection of minimal residual disease identifies differences in treatment response between T-ALL and precursor B-ALL.
Blood 2002;99(12):4386-93.
2002: van der Velden V H J; Willemse M J; van der Schoot C E; Hählen K; van Wering E R; van Dongen J J M
Immunoglobulin kappa deleting element rearrangements in precursor-B acute lymphoblastic leukemia are stable targets for detection of minimal residual disease by real-time quantitative PCR.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(5):928-36.
2002: van der Burg M; Smit B; Brinkhof B; Barendregt B H; Verschuren M C M; Dib M; Beverloo H B; van Dongen J J M; Langerak A W
A single split-signal FISH probe set allows detection of TAL1 translocations as well as SIL-TAL1 fusion genes in a single test.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(4):755-61.
2002: Szczepanski Tomasz; Willemse Marja J; Brinkhof Bas; van Wering Elisabeth R; van der Burg Mirjam; van Dongen Jacques J M
Comparative analysis of Ig and TCR gene rearrangements at diagnosis and at relapse of childhood precursor-B-ALL provides improved strategies for selection of stable PCR targets for monitoring of minimal residual disease.
Blood 2002;99(7):2315-23.
2002: Szczepanski Tomasz; Flohr Thomas; van der Velden Vincent H J; Bartram Claus R; van Dongen Jacques J M
Molecular monitoring of residual disease using antigen receptor genes in childhood acute lymphoblastic leukaemia.
Best practice & research. Clinical haematology 2002;15(1):37-57.
2002: Boeckx N; Willemse M J; Szczepanski T; van der Velden V H J; Langerak A W; Vandekerckhove P; van Dongen J J M
Fusion gene transcripts and Ig/TCR gene rearrangements are complementary but infrequent targets for PCR-based detection of minimal residual disease in acute myeloid leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(3):368-75.
2002: Noordzij Jeroen G; de Bruin-Versteeg Sandra; Comans-Bitter W Marieke; Hartwig Nico G; Hendriks Rudolf W; de Groot Ronald; van Dongen Jacques J M
Composition of precursor B-cell compartment in bone marrow from patients with X-linked agammaglobulinemia compared with healthy children.
Pediatric research 2002;51(2):159-68.
2002: de Haas V; Breunis W B; Dee R; Verhagen O J H M; Kroes W; van Wering E R; van Dongen J J M; van den Berg H; van der Schoot C E
The TEL-AML1 real-time quantitative polymerase chain reaction (PCR) might replace the antigen receptor-based genomic PCR in clinical minimal residual disease studies in children with acute lymphoblastic leukaemia.
British journal of haematology 2002;116(1):87-93.
2002: Hoelzer Dieter; Gökbuget Nicola; Ottmann Oliver; Pui Ching-Hon; Relling Mary V; Appelbaum Frederick R; van Dongen Jacques J M; Szczepanski Tomasz
Acute lymphoblastic leukemia.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2002;():162-92.
2001: Aleman K; Noordzij J G; de Groot R; van Dongen J J; Hartwig N G
Reviewing Omenn syndrome.
European journal of pediatrics 2001;160(12):718-25.
2001: Hazenberg M D; Verschuren M C; Hamann D; Miedema F; van Dongen J J
T cell receptor excision circles as markers for recent thymic emigrants: basic aspects, technical approach, and guidelines for interpretation.
Journal of molecular medicine (Berlin, Germany) 2001;79(11):631-40.
2001: de Vries E; Noordzij J G; Kuijpers T W; van Dongen J J
Flow cytometric immunophenotyping in the diagnosis and follow-up of immunodeficient children.
European journal of pediatrics 2001;160(10):583-91.
2001: Langerak A W; Wolvers-Tettero I L; van Gastel-Mol E J; Oud M E; van Dongen J J
Basic helix-loop-helix proteins E2A and HEB induce immature T-cell receptor rearrangements in nonlymphoid cells.
Blood 2001;98(8):2456-65.
2001: van der Velden V H; Joosten S A; Willemse M J; van Wering E R; Lankester A W; van Dongen J J; Hoogerbrugge P M
Real-time quantitative PCR for detection of minimal residual disease before allogeneic stem cell transplantation predicts outcome in children with acute lymphoblastic leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(9):1485-7.
2001: Szczepanski T; Willemse M J; van Wering E R; van Weerden J F; Kamps W A; van Dongen J J
Precursor-B-ALL with D(H)-J(H) gene rearrangements have an immature immunogenotype with a high frequency of oligoclonality and hyperdiploidy of chromosome 14.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(9):1415-23.
2001: van Wering E R; van der Linden-Schrever B E; van der Velden V H; Szczepanski T; van Dongen J J
T-lymphocytes in bone marrow samples of children with acute lymphoblastic leukemia during and after chemotherapy might hamper PCR-based minimal residual disease studies.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(8):1301-3.
2001: Lucio P; Gaipa G; van Lochem E G; van Wering E R; Porwit-MacDonald A; Faria T; Bjorklund E; Biondi A; van den Beemd M W; Baars E; Vidriales B; Parreira A; van Dongen J J; San Miguel J F; Orfao A;
BIOMED-I concerted action report: flow cytometric immunophenotyping of precursor B-ALL with standardized triple-stainings. BIOMED-1 Concerted Action Investigation of Minimal Residual Disease in Acute Leukemia: International Standardization and Clinical Evaluation.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(8):1185-92.
2001: van der Velden V H; Willemse M J; Mulder M F; Szczepanski T; Langerak A W; Wijkhuijs J M; van Dongen J J
Clearance of maternal leukaemic cells in a neonate.
British journal of haematology 2001;114(1):104-6.
2001: van der Burg M; Barendregt B H; van Wering E R; Langerak A W; Szczepanski T; van Dongen J J
The presence of somatic mutations in immunoglobulin genes of B cell acute lymphoblastic leukemia (ALL-L3) supports assignment as Burkitt's leukemia-lymphoma rather than B-lineage ALL.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(7):1141-3.
2001: Sievers E L; Larson R A; Stadtmauer E A; Estey E; Löwenberg B; Dombret H; Karanes C; Theobald M; Bennett J M; Sherman M L; Berger M S; Eten C B; Loken M R; van Dongen J J; Bernstein I D; Appelbaum F R;
Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(13):3244-54.
2001: Langerak A W; van Krieken J H; Wolvers-Tettero I L; Kerkhof E; Mulder A H; Vrints L W; Coebergh J W; Schuuring E; Kluin P M; van Dongen J J
The role of molecular analysis of immunoglobulin and T cell receptor gene rearrangements in the diagnosis of lymphoproliferative disorders.
Journal of clinical pathology 2001;54(7):565-7.
2001: Langerak A W; van Den Beemd R; Wolvers-Tettero I L; Boor P P; van Lochem E G; Hooijkaas H; van Dongen J J
Molecular and flow cytometric analysis of the Vbeta repertoire for clonality assessment in mature TCRalphabeta T-cell proliferations.
Blood 2001;98(1):165-73.
2001: van der Velden V H; Schoch C; Langerak A W; Schnittger S; Hoogeveen P G; van Dongen J J
Low frequency of reverse transcription polymerase chain reaction-detectable chromosome aberrations in relapsed acute myeloid leukaemia: implications for detection of minimal residual disease.
British journal of haematology 2001;113(4):1082-3.
2001: Bierings M; Szczepanski T; van Wering E R; Willemse M J; Langerak A W; Révész T; van Dongen J J
Two consecutive immunophenotypic switches in a child with immunogenotypically stable acute leukaemia.
British journal of haematology 2001;113(3):757-62.
2001: van Der Velden V H; te Marvelde J G; Hoogeveen P G; Bernstein I D; Houtsmuller A B; Berger M S; van Dongen J J
Targeting of the CD33-calicheamicin immunoconjugate Mylotarg (CMA-676) in acute myeloid leukemia: in vivo and in vitro saturation and internalization by leukemic and normal myeloid cells.
Blood 2001;97(10):3197-204.
2001: Szczepanski T; Willemse M J; Kamps W A; van Wering E R; Langerak A W; van Dongen J J
Molecular discrimination between relapsed and secondary acute lymphoblastic leukemia: proposal for an easy strategy.
Medical and pediatric oncology 2001;36(3):352-8.
2001: van der Burg M; Tümkaya T; Boerma M; de Bruin-Versteeg S; Langerak A W; van Dongen J J
Ordered recombination of immunoglobulin light chain genes occurs at the IGK locus but seems less strict at the IGL locus.
Blood 2001;97(4):1001-8.
2001: Tümkaya T; van der Burg M; Garcia Sanz R; Gonzalez Diaz M; Langerak A W; San Miguel J F; van Dongen J J
Immunoglobulin lambda isotype gene rearrangements in B cell malignancies.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(1):121-7.
2000: Biondi A; Valsecchi M G; Seriu T; D'Aniello E; Willemse M J; Fasching K; Pannunzio A; Gadner H; Schrappe M; Kamps W A; Bartram C R; van Dongen J J; Panzer-Grümayer E R
Molecular detection of minimal residual disease is a strong predictive factor of relapse in childhood B-lineage acute lymphoblastic leukemia with medium risk features. A case control study of the International BFM study group.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2000;14(11):1939-43.
2000: Hazenberg M D; Otto S A; Cohen Stuart J W; Verschuren M C; Borleffs J C; Boucher C A; Coutinho R A; Lange J M; Rinke de Wit T F; Tsegaye A; van Dongen J J; Hamann D; de Boer R J; Miedema F
Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection.
Nature medicine 2000;6(9):1036-42.
2000: Verhagen O J; Willemse M J; Breunis W B; Wijkhuijs A J; Jacobs D C; Joosten S A; van Wering E R; van Dongen J J; van der Schoot C E
Application of germline IGH probes in real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2000;14(8):1426-35.
2000: van den Beemd R; Boor P P; van Lochem E G; Hop W C; Langerak A W; Wolvers-Tettero I L; Hooijkaas H; van Dongen J J
Flow cytometric analysis of the Vbeta repertoire in healthy controls.
Cytometry 2000;40(4):336-45.
2000: Szczepanski T; van 't Veer M B; Wolvers-Tettero I L; Langerak A W; van Dongen J J
Molecular features responsible for the absence of immunoglobulin heavy chain protein synthesis in an IgH(-) subgroup of multiple myeloma.
Blood 2000;96(3):1087-93.
2000: van Wering E R; van der Linden-Schrever B E; Szczepanski T; Willemse M J; Baars E A; van Wijngaarde-Schmitz H M; Kamps W A; van Dongen J J
Regenerating normal B-cell precursors during and after treatment of acute lymphoblastic leukaemia: implications for monitoring of minimal residual disease.
British journal of haematology 2000;110(1):139-46.
2000: Szczepanski T; Langerak A W; Willemse M J; Wolvers-Tettero I L; van Wering E R; van Dongen J J
T cell receptor gamma (TCRG) gene rearrangements in T cell acute lymphoblastic leukemia refelct 'end-stage' recombinations: implications for minimal residual disease monitoring.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2000;14(7):1208-14.
2000: Noordzij J G; Verkaik N S; Hartwig N G; de Groot R; van Gent D C; van Dongen J J
N-terminal truncated human RAG1 proteins can direct T-cell receptor but not immunoglobulin gene rearrangements.
Blood 2000;96(1):203-9.
2000: de Vries E; de Bruin-Versteeg S; Comans-Bitter W M; de Groot R; Hop W C; Boerma G J; Lotgering F K; Sauer P J; van Dongen J J
Neonatal blood lymphocyte subpopulations: a different perspective when using absolute counts.
Biology of the neonate 2000;77(4):230-5.
2000: Porwit-MacDonald A; Björklund E; Lucio P; van Lochem E G; Mazur J; Parreira A; van den Beemd M W; van Wering E R; Baars E; Gaipa G; Biondi A; Ciudad J; van Dongen J J; San Miguel J F; Orfao A
BIOMED-1 concerted action report: flow cytometric characterization of CD7+ cell subsets in normal bone marrow as a basis for the diagnosis and follow-up of T cell acute lymphoblastic leukemia (T-ALL).
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2000;14(5):816-25.
2000: van Lochem E G; Wiegers Y M; van den Beemd R; Hählen K; van Dongen J J; Hooijkaas H
Regeneration pattern of precursor-B-cells in bone marrow of acute lymphoblastic leukemia patients depends on the type of preceding chemotherapy.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2000;14(4):688-95.
2000: de Vries E; de Bruin-Versteeg S; Comans-Bitter W M; de Groot R; Hop W C; Boerma G J; Lotgering F K; van Dongen J J
Longitudinal survey of lymphocyte subpopulations in the first year of life.
Pediatric research 2000;47(4 Pt 1):528-37.
2000: van der Burg M; de Groot R; Comans-Bitter W M; den Hollander J C; Hooijkaas H; Neijens H J; Berger R M; Oranje A P; Langerak A W; van Dongen J J
Autoimmune lymphoproliferative syndrome (ALPS) in a child from consanguineous parents: a dominant or recessive disease?
Pediatric research 2000;47(3):336-43.
2000: Romanow W J; Langerak A W; Goebel P; Wolvers-Tettero I L; van Dongen J J; Feeney A J; Murre C
E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells.
Molecular cell 2000;5(2):343-53.
1999: San Miguel J F; Ciudad J; Vidriales M B; Orfao A; Lucio P; Porwit-MacDonald A; Gaipa G; van Wering E; van Dongen J J
Immunophenotypical detection of minimal residual disease in acute leukemia.
Critical reviews in oncology/hematology 1999;32(3):175-85.
1999: van der Burg M; Beverloo H B; Langerak A W; Wijsman J; van Drunen E; Slater R; van Dongen J J
Rapid and sensitive detection of all types of MLL gene translocations with a single FISH probe set.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(12):2107-13.
1999: van Dongen J J; Macintyre E A; Gabert J A; Delabesse E; Rossi V; Saglio G; Gottardi E; Rambaldi A; Dotti G; Griesinger F; Parreira A; Gameiro P; Diáz M G; Malec M; Langerak A W; San Miguel J F; Biondi A
Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: investigation of minimal residual disease in acute leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(12):1901-28.
1999: Moreau E J; Langerak A W; van Gastel-Mol E J; Wolvers-Tettero I L; Zhan M; Zhou Q; Koop B F; van Dongen J J
Easy detection of all T cell receptor gamma (TCRG) gene rearrangements by Southern blot analysis: recommendations for optimal results.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(10):1620-6.
1999: de Vries E; Noordzij J G; Davies E G; Hartwig N; Breuning M H; van Dongen J J; van Tol M J
The 78C --> T (T254M) XHIM mutation: lack of a tight phenotype-genotype relationship.
Blood 1999;94(4):1488-90.
1999: Derksen P W; Langerak A W; Kerkhof E; Wolvers-Tettero I L; Boor P P; Mulder A H; Vrints L W; Coebergh J W; van Krieken J H; Schuuring E; Kluin P M; van Dongen J J
Comparison of different polymerase chain reaction-based approaches for clonality assessment of immunoglobulin heavy-chain gene rearrangements in B-cell neoplasia.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1999;12(8):794-805.
1999: Verhagen O J; Wijkhuijs A J; van der Sluijs-Gelling A J; Szczepanski T; van der Linden-Schrever B E; Pongers-Willemse M J; van Wering E R; van Dongen J J; van der Schoot C E
Suitable DNA isolation method for the detection of minimal residual disease by PCR techniques.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(8):1298-9.
1999: de Vries E; de Groot R; de Bruin-Versteeg S; Comans-Bitter W M; van Dongen J J
Analysing the developing lymphocyte system of neonates and infants.
European journal of pediatrics 1999;158(8):611-7.
1999: Szczepanski T; Pongers-Willemse M J; Langerak A W; Harts W A; Wijkhuijs A J; van Wering E R; van Dongen J J
Ig heavy chain gene rearrangements in T-cell acute lymphoblastic leukemia exhibit predominant DH6-19 and DH7-27 gene usage, can result in complete V-D-J rearrangements, and are rare in T-cell receptor alpha beta lineage.
Blood 1999;93(12):4079-85.
1999: Langerak A W; Wolvers-Tettero I L; van Dongen J J
Detection of T cell receptor beta (TCRB) gene rearrangement patterns in T cell malignancies by Southern blot analysis.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(6):965-74.
1999: Blom B; Heemskerk M H; Verschuren M C; van Dongen J J; Stegmann A P; Bakker A Q; Couwenberg F; Res P C; Spits H
Disruption of alpha beta but not of gamma delta T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors.
The EMBO journal 1999;18(10):2793-802.
1999: Blom B; Verschuren M C; Heemskerk M H; Bakker A Q; van Gastel-Mol E J; Wolvers-Tettero I L; van Dongen J J; Spits H
TCR gene rearrangements and expression of the pre-T cell receptor complex during human T-cell differentiation.
Blood 1999;93(9):3033-43.
1999: de Vries E; de Bruin-Versteeg S; Comans-Bitter W M; de Groot R; Boerma G J; Lotgering F K; van Dongen J J
Correction for erythroid cell contamination in microassay for immunophenotyping of neonatal lymphocytes.
Archives of disease in childhood. Fetal and neonatal edition 1999;80(3):F226-9.
1999: Ciudad J; San Miguel J F; López-Berges M C; García Marcos M A; González M; Vázquez L; del Cañizo M C; López A; Van Dongen J J; Orfao A
Detection of abnormalities in B-cell differentiation pattern is a useful tool to predict relapse in precursor-B-ALL.
British journal of haematology 1999;104(4):695-705.
1999: Lúcio P; Parreira A; van den Beemd M W; van Lochem E G; van Wering E R; Baars E; Porwit-MacDonald A; Bjorklund E; Gaipa G; Biondi A; Orfao A; Janossy G; van Dongen J J; San Miguel J F
Flow cytometric analysis of normal B cell differentiation: a frame of reference for the detection of minimal residual disease in precursor-B-ALL.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(3):419-27.
1999: Langerak A W; Wolvers-Tettero I L; van den Beemd M W; van Wering E R; Ludwig W D; Hählen K; Necker A; van Dongen J J
Immunophenotypic and immunogenotypic characteristics of TCRgammadelta+ T cell acute lymphoblastic leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(2):206-14.
1999: Szczepanski T; Beishuizen A; Pongers-Willemse M J; Hählen K; Van Wering E R; Wijkhuijs A J; Tibbe G J; De Bruijn M A; Van Dongen J J
Cross-lineage T cell receptor gene rearrangements occur in more than ninety percent of childhood precursor-B acute lymphoblastic leukemias: alternative PCR targets for detection of minimal residual disease.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(2):196-205.
1999: Pongers-Willemse M J; Seriu T; Stolz F; d'Aniello E; Gameiro P; Pisa P; Gonzalez M; Bartram C R; Panzer-Grümayer E R; Biondi A; San Miguel J F; van Dongen J J
Primers and protocols for standardized detection of minimal residual disease in acute lymphoblastic leukemia using immunoglobulin and T cell receptor gene rearrangements and TAL1 deletions as PCR targets: report of the BIOMED-1 CONCERTED ACTION: investigation of minimal residual disease in acute leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(1):110-8.
1999: Szczepanski T; Pongers-Willemse M J; Langerak A W; van Dongen J J
Unusual immunoglobulin and T-cell receptor gene rearrangement patterns in acute lymphoblastic leukemias.
Current topics in microbiology and immunology 1999;246():205-13; discussion 214-5.
1998: Verschuren M C; Blom B; Bogers A J; Spits H; van Dongen J J
PJA-BP expression and TCR delta deletion during human T cell differentiation.
International immunology 1998;10(12):1873-80.
1998: Pongers-Willemse M J; Verhagen O J; Tibbe G J; Wijkhuijs A J; de Haas V; Roovers E; van der Schoot C E; van Dongen J J
Real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia using junctional region specific TaqMan probes.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1998;12(12):2006-14.
1998: van Dongen J J; Seriu T; Panzer-Grümayer E R; Biondi A; Pongers-Willemse M J; Corral L; Stolz F; Schrappe M; Masera G; Kamps W A; Gadner H; van Wering E R; Ludwig W D; Basso G; de Bruijn M A; Cazzaniga G; Hettinger K; van der Does-van den Berg A; Hop W C; Riehm H; Bartram C R
Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood.
Lancet 1998;352(9142):1731-8.
1998: Spits H; Blom B; Jaleco A C; Weijer K; Verschuren M C; van Dongen J J; Heemskerk M H; Res P C
Early stages in the development of human T, natural killer and thymic dendritic cells.
Immunological reviews 1998;165():75-86.
1998: de Vries E; de Bruin-Versteeg S; Comans-Bitter W M; van Dongen J J; de Groot R; Boerma G J; Lotgering F K
Longitudinal follow-up of blood lymphocyte subpopulations from birth to 1 year of age.
The Journal of pediatrics 1998;133(4):586-8.
1998: Szczepanski T; Pongers-Willemse M J; Hählen K; van Dongen J J
Intensified therapy for infants with acute lymphoblastic leukemia: results from the Dana-Farber Cancer Institute Consortium.
Cancer 1998;83(5):1055-7.
1998: Szczepanski T; Langerak A W; van Dongen J J; van Krieken J H
Lymphoma with multi-gene rearrangement on the level of immunoglobulin heavy chain, light chain, and T-cell receptor beta chain.
American journal of hematology 1998;59(1):99-100.
1998: Szczepanski T; Langerak A W; Wolvers-Tettero I L; Ossenkoppele G J; Verhoef G; Stul M; Petersen E J; de Bruijn M A; van't Veer M B; van Dongen J J
Immunoglobulin and T cell receptor gene rearrangement patterns in acute lymphoblastic leukemia are less mature in adults than in children: implications for selection of PCR targets for detection of minimal residual disease.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1998;12(7):1081-8.
1998: Kluin-Nelemans H C; Kester M G; van deCorput L; Boor P P; Landegent J E; van Dongen J J; Willemze R; Falkenburg J H
Correction of abnormal T-cell receptor repertoire during interferon-alpha therapy in patients with hairy cell leukemia.
Blood 1998;91(11):4224-31.
1998: Massari M E; Rivera R R; Voland J R; Quong M W; Breit T M; van Dongen J J; de Smit O; Murre C
Characterization of ABF-1, a novel basic helix-loop-helix transcription factor expressed in activated B lymphocytes.
Molecular and cellular biology 1998;18(6):3130-9.
1998: Verschuren M C; Wolvers-Tettero I L; Breit T M; van Dongen J J
T-cell receptor V delta-J alpha rearrangements in human thymocytes: the role of V delta-J alpha rearrangements in T-cell receptor-delta gene deletion.
Immunology 1998;93(2):208-12.
1997: Van Lochem E G; Groeneveld K; Te Marvelde J G; Van den Beemd M W; Hooijkaas H; Van Dongen J J
Flow cytometric detection of intracellular antigens for immunophenotyping of normal and malignant leukocytes: testing of a new fixation-permeabilization solution.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1997;11(12):2208-10.
1997: Beishuizen A; de Bruijn M A; Pongers-Willemse M J; Verhoeven M A; van Wering E R; Hählen K; Breit T M; de Bruin-Versteeg S; Hooijkaas H; van Dongen J J
Heterogeneity in junctional regions of immunoglobulin kappa deleting element rearrangements in B cell leukemias: a new molecular target for detection of minimal residual disease.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1997;11(12):2200-7.
1997: Langerak A W; Szczepanski T; van der Burg M; Wolvers-Tettero I L; van Dongen J J
Heteroduplex PCR analysis of rearranged T cell receptor genes for clonality assessment in suspect T cell proliferations.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1997;11(12):2192-9.
1997: Breit T M; Verschuren M C; Wolvers-Tettero I L; Van Gastel-Mol E J; Hählen K; van Dongen J J
Human T cell leukemias with continuous V(D)J recombinase activity for TCR-delta gene deletion.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(9):4341-9.
1997: Hoijer M A; Melief M J; Calafat J; Roos D; van den Beemd R W; van Dongen J J; Hazenberg M P
Expression and intracellular localization of the human N-acetylmuramyl-L-alanine amidase, a bacterial cell wall-degrading enzyme.
Blood 1997;90(3):1246-54.
1997: Comans-Bitter W M; de Groot R; van den Beemd R; Neijens H J; Hop W C; Groeneveld K; Hooijkaas H; van Dongen J J
Immunophenotyping of blood lymphocytes in childhood. Reference values for lymphocyte subpopulations.
The Journal of pediatrics 1997;130(3):388-93.
1997: Verschuren M C; Wolvers-Tettero I L; Breit T M; Noordzij J; van Wering E R; van Dongen J J
Preferential rearrangements of the T cell receptor-delta-deleting elements in human T cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(3):1208-16.
1996: Tümkaya T; Beishuizen A; Wolvers-Tettero I L; van Dongen J J
Identification of immunoglobulin lambda isotype gene rearrangements by Southern blot analysis.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1996;10(11):1834-9.
1996: Groeneveld K; te Marvelde J G; van den Beemd M W; Hooijkaas H; van Dongen J J
Flow cytometric detection of intracellular antigens for immunophenotyping of normal and malignant leukocytes.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1996;10(8):1383-9.
1996: van Dongen J J; Szczepanski T; de Bruijn M A; van den Beemd M W; de Bruin-Versteeg S; Wijkhuijs J M; Tibbe G J; van Gastel-Mol E J; Groeneveld K; Hooijkaas H
Detection of minimal residual disease in acute leukemia patients.
Cytokines and molecular therapy 1996;2(2):121-33.
1996: Verschuren M C; van Bergen C J; van Gastel-Mol E J; Bogers A J; van Dongen J J
A DNA binding protein in human thymocytes recognizes the T cell receptor-delta-deleting element psi J alpha.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(10):3806-14.
1995: van Dongen J J
Proposals for immunological classification of acute leukemias.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(12):2149-50.
1995: Tümkaya T; Comans-Bitter W M; Verhoeven M A; van Dongen J J
Southern blot detection of immunoglobulin lambda light chain gene rearrangements for clonality studies.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(12):2127-32.
1995: van Wering E R; Beishuizen A; Roeffen E T; van der Linden-Schrever B E; Verhoeven M A; Hählen K; Hooijkaas H; van Dongen J J
Immunophenotypic changes between diagnosis and relapse in childhood acute lymphoblastic leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(9):1523-33.
1994: Beishuizen A; Verhoeven M A; Mol E J; van Dongen J J
Detection of immunoglobulin kappa light-chain gene rearrangement patterns by Southern blot analysis.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1994;8(12):2228-36; discussion 2237-9.
1994: Breit T M; Wolvers-Tettero I L; van Dongen J J
Lineage specific demethylation of tal-1 gene breakpoint region determines the frequency of tal-1 deletions in alpha beta lineage T-cells.
Oncogene 1994;9(7):1847-53.
1994: Beishuizen A; Verhoeven M A; van Wering E R; Hählen K; Hooijkaas H; van Dongen J J
Analysis of Ig and T-cell receptor genes in 40 childhood acute lymphoblastic leukemias at diagnosis and subsequent relapse: implications for the detection of minimal residual disease by polymerase chain reaction analysis.
Blood 1994;83(8):2238-47.
1994: Breit T M; Wolvers-Tettero I L; van Dongen J J
Unique selection determinant in polyclonal V delta 2-J delta 1 junctional regions of human peripheral gamma delta T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(6):2860-4.
1994: Breit T M; Wolvers-Tettero I L; van Dongen J J
Phenotypic and genotypic characteristics of human early T-cell differentiation: the T-cell acute lymphoblastic leukaemia model.
Research in immunology 1994;145(2):139-43; discussion 155-8.
1994: Los F J; Van Hemel J O; Jacobs H J; Drop S L; van Dongen J J
De novo deletion (2) (p11.2p13): clinical, cytogenetic, and immunological data.
Journal of medical genetics 1994;31(1):72-3.
1994: Breit T M; Wolvers-Tettero I L; Bogers A J; de Krijger R R; Wladimiroff J W; van Dongen J J
Rearrangements of the human TCRD-deleting elements.
Immunogenetics 1994;40(1):70-5.
1994: Breit T M; Van Dongen J J
Unravelling human T-cell receptor junctional region sequences.
Thymus 1994;22(3):177-99.
1993: Breit T M; Beishuizen A; Ludwig W D; Mol E J; Adriaansen H J; van Wering E R; van Dongen J J
tal-1 deletions in T-cell acute lymphoblastic leukemia as PCR target for detection of minimal residual disease.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1993;7(12):2004-11.
1993: Verschuren M C; Comans-Bitter W M; Kapteijn C A; Mason D Y; Brouns G S; Borst J; Drexler H G; van Dongen J J
Transcription and protein expression of mb-1 and B29 genes in human hematopoietic malignancies and cell lines.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1993;7(12):1939-47.
1993: Beishuizen A; Verhoeven M A; Mol E J; Breit T M; Wolvers-Tettero I L; van Dongen J J
Detection of immunoglobulin heavy-chain gene rearrangements by Southern blot analysis: recommendations for optimal results.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1993;7(12):2045-53.
1993: Breit T M; Wolvers-Tettero I L; Beishuizen A; Verhoeven M A; van Wering E R; van Dongen J J
Southern blot patterns, frequencies, and junctional diversity of T-cell receptor-delta gene rearrangements in acute lymphoblastic leukemia.
Blood 1993;82(10):3063-74.
1993: Sonneveld P; van Dongen J J; Hagemeijer A; van Lom K; Nooter K; Schoester M; Adriaansen H J; Tsuruo T; de Leeuw K
High expression of the multidrug resistance P-glycoprotein in high-risk myelodysplasia is associated with immature phenotype.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1993;7(7):963-9.
1993: Beishuizen A; Verhoeven M A; Hählen K; van Wering E R; van Dongen J J
Differences in immunoglobulin heavy chain gene rearrangmeent patterns between bone marrow and blood samples in childhood precursor B-acute lymphoblastic leaukemia at diagnosis.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1993;7(6):60-3.
1993: Adriaansen H J; te Boekhorst P A; Hagemeijer A M; van der Schoot C E; Delwel H R; van Dongen J J
Acute myeloid leukemia M4 with bone marrow eosinophilia (M4Eo) and inv(16)(p13q22) exhibits a specific immunophenotype with CD2 expression.
Blood 1993;81(11):3043-51.
1993: Knulst A C; Adriaansen H J; Hählen K; Stigter J C; van den Beemd M W; Hagemeijer A; van Dongen J J; Hooijkaas H
Early diagnosis of smoldering acute lymphoblastic leukemia using immunological marker analysis.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1993;7(4):532-6.
1993: Breit T M; Mol E J; Wolvers-Tettero I L; Ludwig W D; van Wering E R; van Dongen J J
Site-specific deletions involving the tal-1 and sil genes are restricted to cells of the T cell receptor alpha/beta lineage: T cell receptor delta gene deletion mechanism affects multiple genes.
The Journal of experimental medicine 1993;177(4):965-77.
1993: Borst J; Brouns G S; de Vries E; Verschuren M C; Mason D Y; van Dongen J J
Antigen receptors on T and B lymphocytes: parallels in organization and function.
Immunological reviews 1993;132():49-84.
1993: Adriaansen H J; Jacobs B C; Kappers-Klunne M C; Hählen K; Hooijkaas H; van Dongen J J
Detection of residual disease in AML patients by use of double immunological marker analysis for terminal deoxynucleotidyl transferase and myeloid markers.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1993;7(3):472-81.
1993: van Wering E R; Brederoo P; van Staalduinen G J; van der Meulen J; van der Linden-Schrever B E; van Dongen J J
Contribution of electron microscopy to the classification of minimally differentiated acute leukemias in children.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1993;131():77-87.
1993: van Dongen J J; Breit T M; Adriaansen H J; Beishuizen A; Hooijkaas H
Immunophenotypic and immunogenotypic detection of minimal residual disease in acute lymphoblastic leukemia.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1993;131():157-84.
1992: Kuijpers K C; van Dongen J J; van der Burg P; Roos M T; Vonk J; de Abreu R; de Korte D; van Noesel C J; Weening R S; van Lier R A
A combined immunodeficiency with oligoclonal CD8+, V beta 3-expressing, cytotoxic T lymphocytes in the peripheral blood.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(10):3403-10.
1992: Mason D Y; van Noesel C J; Cordell J L; Comans-Bitter W M; Micklem K; Tse A G; van Lier R A; van Dongen J J
The B29 and mb-1 polypeptides are differentially expressed during human B cell differentiation.
European journal of immunology 1992;22(10):2753-6.
1992: van Oostveen J W; Breit T M; de Wolf J T; Brandt R M; Smit J W; van Dongen J J; Borst J; Melief C J
Polyclonal expansion of T-cell receptor-gamma delta+ T lymphocytes associated with neutropenia and thrombocytopenia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1992;6(5):410-8.
1992: Sonneveld P; Nooter K; Burghouts J T; Herweijer H; Adriaansen H J; van Dongen J J
High expression of the mdr3 multidrug-resistance gene in advanced-stage chronic lymphocytic leukemia.
Blood 1992;79(6):1496-500.
1992: Breit T M; Wolvers-Tettero L M; Hählen K; van Wering E R; van Dongen J J
Extensive junctional diversity of gamma delta T-cell receptors expressed by T-cell acute lymphoblastic leukemias: implications for the detection of minimal residual disease.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1992;6(2):169-70.
1992: van Dongen J J; Breit T M; Adriaansen H J; Beishuizen A; Hooijkaas H
Detection of minimal residual disease in acute leukemia by immunological marker analysis and polymerase chain reaction.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1992;6 Suppl 1():47-59.
1992: Breit T M; Wolvers-Tettero I L; van Dongen J J
Receptor diversity of human T-cell receptor gamma delta expressing cells.
Progress in histochemistry and cytochemistry 1992;26(1-4):182-93.
1991: Breit T M; Wolvers-Tettero I L; Hählen K; van Wering E R; van Dongen J J
Extensive junctional diversity of gamma delta T-cell receptors expressed by T-cell acute lymphoblastic leukemias: implications for the detection of minimal residual disease.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1991;5(12):1076-86.
1991: Mason D Y; Cordell J L; Tse A G; van Dongen J J; van Noesel C J; Micklem K; Pulford K A; Valensi F; Comans-Bitter W M; Borst J
The IgM-associated protein mb-1 as a marker of normal and neoplastic B cells.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(11):2474-82.
1991: Adriaansen H J; Soeting P W; Wolvers-Tettero I L; van Dongen J J
Immunoglobulin and T-cell receptor gene rearrangements in acute non-lymphocytic leukemias. Analysis of 54 cases and a review of the literature.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1991;5(9):744-51.
1991: Beishuizen A; Hählen K; Hagemeijer A; Verhoeven M A; Hooijkaas H; Adriaansen H J; Wolvers-Tettero I L; van Wering E R; van Dongen J J
Multiple rearranged immunoglobulin genes in childhood acute lymphoblastic leukemia of precursor B-cell origin.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1991;5(8):657-67.
1991: van Dongen J J; Wolvers-Tettero I L
Analysis of immunoglobulin and T cell receptor genes. Part II: Possibilities and limitations in the diagnosis and management of lymphoproliferative diseases and related disorders.
Clinica chimica acta; international journal of clinical chemistry 1991;198(1-2):93-174.
1991: van Dongen J J; Wolvers-Tettero I L
Analysis of immunoglobulin and T cell receptor genes. Part I: Basic and technical aspects.
Clinica chimica acta; international journal of clinical chemistry 1991;198(1-2):1-91.
1991: Rijkers G T; Scharenberg J G; Van Dongen J J; Neijens H J; Zegers B J
Abnormal signal transduction in a patient with severe combined immunodeficiency disease.
Pediatric research 1991;29(3):306-9.
1991: Breit T M; Wolvers-Tettero I L; Hählen K; van Wering E R; van Dongen J J
Limited combinatorial repertoire of gamma delta T-cell receptors expressed by T-cell acute lymphoblastic leukemias.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1991;5(2):116-24.
1991: van der Kwast T H; van Dongen J J; Michiels J J; Hooijkaas H; Kappers M C; Hagemeijer A
T-lymphoblastic lymphoma terminating as malignant histiocytosis with rearrangement of immunoglobulin heavy chain gene.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1991;5(1):78-82.
1991: Borst J; Vroom T M; Bos J D; Van Dongen J J
Tissue distribution and repertoire selection of human gamma delta T cells: comparison with the murine system.
Current topics in microbiology and immunology 1991;173():41-6.
1991: Herweijer H; Nooter K; Beishuizen A; Sonneveld P; Oostrum R G; Hesseling-Janssen A L; van Dongen J J
Expression of mdr1 and mdr3 multidrug-resistance genes in hairy cell leukaemia.
European journal of cancer (Oxford, England : 1990) 1991;27(3):297-8.
1990: Adriaansen H J; Osman C; van Dongen J J; Wijdenes-de Bresser J H; Kappetijn-van Tilborg C M; Hooijkaas H
Immunological marker analysis of mitogen-induced proliferating lymphocytes using BrdU incorporation or screening of metaphases. Staphylococcal protein A is a potent mitogen for CD4+ lymphocytes.
Scandinavian journal of immunology 1990;32(6):687-94.
1990: van Dongen J J; Comans-Bitter W M; Wolvers-Tettero I L; Borst J
Development of human T lymphocytes and their thymus-dependency.
Thymus 1990;16(3-4):207-34.
1990: Borst J; van Dongen J J; de Vries E; Comans-Bitter W M; van Tol M J; Vossen J M; Kurrle R
BMA031, a monoclonal antibody suited to identify the T-cell receptor alpha beta/CD3 complex on viable human T lymphocytes in normal and disease states.
Human immunology 1990;29(3):175-88.
1990: Borst J; van Dongen J J
Repertoire selection of human gamma delta T cells.
Research in immunology 1990;141(7):663-8.
1990: Adriaansen H J; van Dongen J J; Kappers-Klunne M C; Hählen K; van 't Veer M B; Wijdenes-de Bresser J H; Holdrinet A C; Harthoorn-Lasthuizen E J; Abels J; Hooijkaas H
Terminal deoxynucleotidyl transferase positive subpopulations occur in the majority of ANLL: implications for the detection of minimal disease.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1990;4(6):404-10.
1990: Mason D Y; Comans-Bitter W M; Cordell J L; Verhoeven M A; van Dongen J J
Antibody L26 recognizes an intracellular epitope on the B-cell-associated CD20 antigen.
The American journal of pathology 1990;136(6):1215-22.
1990: Adriaansen H J; Guerts van Kessel A H; Wijdenes-de Bresser J H; van Drunen-Schoenmaker E; van Dongen J J
Expression of the myeloid differentiation antigen CD33 depends on the presence of human chromosome 19 in human-mouse hybrids.
Annals of human genetics 1990;54(Pt 2):115-9.
1990: Adriaansen H J; Hooijkaas H; Kappers-Klunne M C; Hählen K; van't Veer M B; van Dongen J J
Double marker analysis for terminal deoxynucleotidyl transferase and myeloid antigens in acute nonlymphocytic leukemia patients and healthy subjects.
Haematology and blood transfusion 1990;33():41-9.
1989: Neijens H J; Frenkel J; de Muinck Keizer-Schrama S M; Dzoljic-Danilovic G; Meradji M; van Dongen J J
Invasive Aspergillus infection in chronic granulomatous disease: treatment with itraconazole.
The Journal of pediatrics 1989;115(6):1016-9.
1989: Michiels J J; van Dongen J J; Hagemeijer A; Sonneveld P; Ploemacher R E; Adriaansen H J; van der Kwast T H; Brederoo P; Abels J
Richter's syndrome with identical immunoglobulin gene rearrangements in the chronic lymphocytic leukemia and the supervening non-Hodgkin lymphoma.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1989;3(11):819-24.
1989: Borst J; Wicherink A; Van Dongen J J; De Vries E; Comans-Bitter W M; Wassenaar F; Van Den Elsen P
Non-random expression of T cell receptor gamma and delta variable gene segments in functional T lymphocyte clones from human peripheral blood.
European journal of immunology 1989;19(9):1559-68.
1989: Hooijkaas H; Hählen K; Adriaansen H J; Dekker I; van Zanen G E; van Dongen J J
Terminal deoxynucleotidyl transferase (TdT)-positive cells in cerebrospinal fluid and development of overt CNS leukemia: a 5-year follow-up study in 113 children with a TdT-positive leukemia or non-Hodgkin's lymphoma.
Blood 1989;74(1):416-22.
1989: van Dongen J J; Wolvers-Tettero I L; Wassenaar F; Borst J; van den Elsen P
Rearrangement and expression of T-cell receptor delta genes in T-cell acute lymphoblastic leukemias.
Blood 1989;74(1):334-42.
1988: Frenkel J; Neijens H J; den Hollander J C; Wolvers-Tettero I L; van Dongen J J
Oligoclonal T cell proliferative disorder in combined immunodeficiency.
Pediatric research 1988;24(5):622-7.
1988: Borst J; van Dongen J J; Bolhuis R L; Peters P J; Hafler D A; de Vries E; van de Griend R J
Distinct molecular forms of human T cell receptor gamma/delta detected on viable T cells by a monoclonal antibody.
The Journal of experimental medicine 1988;167(5):1625-44.
1988: Michiels J J; Adriaansen H J; Hagemeijer A; Hooijkaas H; van Dongen J J; Abels J
TdT positive B-cell acute lymphoblastic leukaemia (B-ALL) without Burkitt characteristics.
British journal of haematology 1988;68(4):423-6.
1988: Adriaansen H J; van Dongen J J; Hooijkaas H; Hählen K; van 't Veer M B; Löwenberg B; Hagemeijer A
Translocation (6;9) may be associated with a specific TdT-positive immunological phenotype in ANLL.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1988;2(3):136-40.
1988: van Dongen J J; Krissansen G W; Wolvers-Tettero I L; Comans-Bitter W M; Adriaansen H J; Hooijkaas H; van Wering E R; Terhorst C
Cytoplasmic expression of the CD3 antigen as a diagnostic marker for immature T-cell malignancies.
Blood 1988;71(3):603-12.
1987: Van Dongen J J; Wolvers-Tettero I L; Seidman J G; Ang S L; Van de Griend R J; De Vries E F; Borst J
Two types of gamma T cell receptors expressed by T cell acute lymphoblastic leukemias.
European journal of immunology 1987;17(12):1719-28.
1987: van Dongen J J; Quertermous T; Bartram C R; Gold D P; Wolvers-Tettero I L; Comans-Bitter W M; Hooijkaas H; Adriaansen H J; de Klein A; Raghavachar A
T cell receptor-CD3 complex during early T cell differentiation. Analysis of immature T cell acute lymphoblastic leukemias (T-ALL) at DNA, RNA, and cell membrane level.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(4):1260-9.
1987: Hagemeijer A; van Dongen J J; Slater R M; van't Veer M B; Behrendt H; Hählen K; Sizoo W; Abels J
Characterization of the blast cells in acute leukemia with translocation (4;11): report of eight additional cases and of one case with a variant translocation.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1987;1(1):24-31.
1987: van Dongen J J; Comans-Bitter W M
Phenotypic and genotypic characteristics of the human prothymocyte.
Immunologic research 1987;6(4):250-62.
1986: Hooijkaas H; Adriaansen H J; Hählen K; van Zanen G E; van Dongen J J
[Terminal deoxynucleotidyltransferase (TdT)-positive cells in cerebrospinal fluid of children with leukemia or non-Hodgkin lymphoma: implications for the diagnosis of central nervous system leukemia]
Tijdschrift voor kindergeneeskunde 1986;54(2):46-50.
1986: van Dongen J J; Hooijkaas H; Adriaansen H J; Hählen K; van Zanen G E
[Detection of low numbers of malignant cells in patients with leukemia or non-Hodgkin lymphoma: use of immunological markers]
Tijdschrift voor kindergeneeskunde 1986;54(2):41-5.
1985: van Dongen J J; Hooijkaas H; Comans-Bitter M; Hählen K; de Klein A; van Zanen G E; van't Veer M B; Abels J; Benner R
Human bone marrow cells positive for terminal deoxynucleotidyl transferase (TdT), HLA-DR, and a T cell marker may represent prothymocytes.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(5):3144-50.
1985: Van Dongen J J; Hooijkaas H; Comans-Bitter W M; Benne K; Van Os T M; De Josselin de Jong J
Triple immunological staining with colloidal gold, fluorescein and rhodamine as labels.
Journal of immunological methods 1985;80(1):1-6.
1985: van Dongen J J; Hooijkaas H; Comans-Bitter W M; Hählen K; van Zanen G E
The small subpopulation of T cell marker+/TdT+ cells in the human bone marrow may represent prothymocytes.
Advances in experimental medicine and biology 1985;186():889-99.
1984: Hooijkaas H; van Dongen J J; Hählen K; van Zanen G E
Immunological characterisation of cells in cerebrospinal fluid from patients with lymphoid malignancies.
Lancet 1984;1(8375):518-9.

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