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Martin van Eijk

Research Profile

Chemicals & Drugs

Concepts & Ideas

Molecular Sequence Data

Living Beings

Anatomy

Genes & Molecular Sequences

Genes, MHC Class II

Physiology

Carbohydrate Metabolism

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Publications

TOP 3
Marine L B Hillaire; Nella J Nieuwkoop; Albert D M E Osterhaus; Ron A M Fouchier; Henk P Haagsman; Martin van Eijk; Stella E Vogelzang-van Trierum; Guus F Rimmelzwaan
The number and position of N-linked glycosylation sites in the hemagglutinin determine differential recognition of seasonal and 2009 pandemic H1N1 influenza virus by porcine surfactant protein D.
Martin van Eijk; Mitchell R White; Xueqing Zou; Tanya R Cafarella; Erika C Crouch; Henk P Haagsman; Kevan L Hartshorn; James F Head; Dong Luo; Michael J Rynkiewicz; Klaus Schulten; Barbara A Seaton
A unique sugar-binding site mediates the distinct anti-influenza activity of pig surfactant protein D.
Elisa Lombardo; Roelof Ottenhoff; Herman S Overkleeft; Martin van Eijk; Gijs H van Puijvelde; Cindy P A A van Roomen; Arthur J Verhoeven; Johannes M F G Aerts; Jan Aten; Albert K Groen; Johan Kuiper; Florence Bietrix
Correction of liver steatosis by a hydrophobic iminosugar modulating glycosphingolipids metabolism.

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All Publications

2012: Marine L B Hillaire; Nella J Nieuwkoop; Albert D M E Osterhaus; Ron A M Fouchier; Henk P Haagsman; Martin van Eijk; Stella E Vogelzang-van Trierum; Guus F Rimmelzwaan
The number and position of N-linked glycosylation sites in the hemagglutinin determine differential recognition of seasonal and 2009 pandemic H1N1 influenza virus by porcine surfactant protein D.
Virus research 2012;169(1):301-5.
2012: Martin van Eijk; Mitchell R White; Xueqing Zou; Tanya R Cafarella; Erika C Crouch; Henk P Haagsman; Kevan L Hartshorn; James F Head; Dong Luo; Michael J Rynkiewicz; Klaus Schulten; Barbara A Seaton
A unique sugar-binding site mediates the distinct anti-influenza activity of pig surfactant protein D.
The Journal of biological chemistry 2012;287(32):26666-77.
2012: Elisa Lombardo; Roelof Ottenhoff; Herman S Overkleeft; Martin van Eijk; Gijs H van Puijvelde; Cindy P A A van Roomen; Arthur J Verhoeven; Johannes M F G Aerts; Jan Aten; Albert K Groen; Johan Kuiper; Florence Bietrix
Correction of liver steatosis by a hydrophobic iminosugar modulating glycosphingolipids metabolism.
PloS one 2012;7(10):e38520.
2011: Edwin J A Veldhuizen; Martin van Eijk; Henk P Haagsman
The carbohydrate recognition domain of collectins.
The FEBS journal 2011;278(20):3930-41.
2011: Martin van Eijk; Laurie Bruinsma; Kevan L Hartshorn; Mitchell R White; Michael J Rynkiewicz; Barbara A Seaton; Wieger Hemrika; Roland A Romijn; Bas W M Van Balkom; Henk P Haagsman
Introduction of N-linked glycans in the lectin domain of surfactant protein D: impact on interactions with influenza A viruses.
The Journal of biological chemistry 2011;286(23):20137-51.
2011: Marine L B Hillaire; Thijs Kuiken; Albert D M E Osterhaus; Roland A Romijn; Xavier Saelens; Martin van Eijk; Debby van Riel; Stella E van Trierum; Ron A M Fouchier; Henk P Haagsman; Wieger Hemrika; Guus F Rimmelzwaan
Assessment of the antiviral properties of recombinant porcine SP-D against various influenza A viruses in vitro.
PloS one 2011;6(9):e25005.
2010: Martin van Eijk; Tineke Voorn-Brouwer; Saskia Scheij; Arthur J Verhoeven; Rolf G Boot; Johannes M F G Aerts
Curdlan-mediated regulation of human phagocyte-specific chitotriosidase.
FEBS letters 2010;584(14):3165-9.
2010: Tom Wennekes; Alfred J Meijer; Albert K Groen; Rolf G Boot; Johanna E M Groener; Martin van Eijk; Roelof Ottenhoff; Nora Bijl; Karen Ghauharali; Hang Song; Tom J O'Shea; Hanlan Liu; Nelson Yew; Diane Copeland; Richard J B H N van den Berg; Gijsbert A van der Marel; Herman S Overkleeft; Johannes M Aerts
Dual-action lipophilic iminosugar improves glycemic control in obese rodents by reduction of visceral glycosphingolipids and buffering of carbohydrate assimilation.
Journal of medicinal chemistry 2010;53(2):689-98.
2009: Nora Bijl; Milka Sokolović; Carlos Vrins; Mirjam Langeveld; Perry Moerland; Roelof Ottenhoff; Cindy P A A van Roomen; Nike Claessen; Rolf G Boot; Jan Aten; Albert K Groen; Johannes M F G Aerts; Martin van Eijk
Modulation of glycosphingolipid metabolism significantly improves hepatic insulin sensitivity and reverses hepatic steatosis in mice.
Hepatology (Baltimore, Md.) 2009;50(5):1431-41.
2009: Nora Bijl; Cindy P A A van Roomen; Vassilis Triantis; Milka Sokolović; Roelof Ottenhoff; Saskia Scheij; Martin van Eijk; Rolf G Boot; Johannes M Aerts; Albert K Groen
Reduction of glycosphingolipid biosynthesis stimulates biliary lipid secretion in mice.
Hepatology (Baltimore, Md.) 2009;49(2):637-45.
2009: Martin van Eijk; Jan Aten; Nora Bijl; Roelof Ottenhoff; Cindy P A A van Roomen; Peter F Dubbelhuis; Ingar Seeman; Karen Ghauharali-van der Vlugt; Herman S Overkleeft; Cynthia Arbeeny; Albert K Groen; Johannes M F G Aerts
Reducing glycosphingolipid content in adipose tissue of obese mice restores insulin sensitivity, adipogenesis and reduces inflammation.
PloS one 2009;4(3):e4723.
2008: Astrid Hogenkamp; Najiha Isohadouten; Sylvia S N Reemers; Roland A Romijn; Wieger Hemrika; Mitchell R White; Boris Tefsen; Lonneke Vervelde; Martin van Eijk; Edwin J A Veldhuizen; Henk P Haagsman
Chicken lung lectin is a functional C-type lectin and inhibits haemagglutination by influenza A virus.
Veterinary microbiology 2008;130(1-2):37-46.
2008: Henk P Haagsman; Astrid Hogenkamp; Martin van Eijk; Edwin J A Veldhuizen
Surfactant collectins and innate immunity.
Neonatology 2008;93(4):288-94.
2007: Martin van Eijk; Saskia Scheij; Cindy P A A van Roomen; Dave Speijer; Rolf G Boot; johannes aerts
TLR- and NOD2-dependent regulation of human phagocyte-specific chitotriosidase.
FEBS letters 2007;581(28):5389-95.
2007: Jörg Hamann; Nathalie Koning; Walter Pouwels; Laurien H Ulfman; Martin van Eijk; Martin Stacey; Hsi-Hsien Lin; Siamon Gordon; Mark J Kwakkenbos
EMR1, the human homolog of F4/80, is an eosinophil-specific receptor.
European journal of immunology 2007;37(10):2797-802.
2007: M Veronica Herías; Astrid Hogenkamp; Alphons J A M van Asten; Monique H G Tersteeg; Martin van Eijk; Henk P Haagsman
Expression sites of the collectin SP-D suggest its importance in first line host defence: power of combining in situ hybridisation, RT-PCR and immunohistochemistry.
Molecular immunology 2007;44(13):3324-32.
2007: Anton P Bussink; Paul F van Swieten; Karen Ghauharali; Saskia Scheij; Martin van Eijk; Tom Wennekes; Gijsbert A van der Marel; Rolf G Boot; johannes aerts; Herman S Overkleeft
N-azidoacetylmannosamine-mediated chemical tagging of gangliosides.
Journal of lipid research 2007;48(6):1417-21.
2007: johannes aerts; Roelof Ottenhoff; Andrew S Powlson; Aldo Grefhorst; Martin van Eijk; Peter F Dubbelhuis; Jan Aten; Folkert Kuipers; Mireille J Serlie; Tom Wennekes; Jaswinder Sethi; Stephen O'Rahilly; Herman S Overkleeft
Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity.
Diabetes 2007;56(5):1341-9.
2007: Xueyi Li; Dora Kaloyanova; Martin van Eijk; Ruud Eerland; Gisou van der Goot; Viola Oorschot; Judith Klumperman; Friedrich Lottspeich; Vytaute Starkuviene; Felix T Wieland; J Bernd Helms
Involvement of a Golgi-resident GPI-anchored protein in maintenance of the Golgi structure.
Molecular biology of the cell 2007;18(4):1261-71.
2006: Kirsten van Nierop; Femke J M Muller; Jan Stap; Cornelis J F Van Noorden; Martin van Eijk; Cornelis de Groot
Lysosomal destabilization contributes to apoptosis of germinal center B-lymphocytes.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2006;54(12):1425-35.
2006: Astrid Hogenkamp; Martin van Eijk; Albert van Dijk; Alphons J A M van Asten; Edwin J A Veldhuizen; Henk P Haagsman
Characterization and expression sites of newly identified chicken collectins.
Molecular immunology 2006;43(10):1604-16.
2006: Kevan L Hartshorn; Antoon J M Ligtenberg; Mitchell R White; Martin van Eijk; Max Hartshorn; Lily Pemberton; Uffe Holmskov; Erika Crouch
Salivary agglutinin and lung scavenger receptor cysteine-rich glycoprotein 340 have broad anti-influenza activities and interactions with surfactant protein D that vary according to donor source and sialylation.
The Biochemical journal 2006;393(Pt 2):545-53.
2006: Anton P Bussink; Martin van Eijk; G Herma Renkema; johannes aerts; Rolf G Boot
The biology of the Gaucher cell: the cradle of human chitinases.
International review of cytology 2006;252():71-128.
2005: Martin van Eijk; Cindy P A A van Roomen; G Herma Renkema; Anton P Bussink; Laura Andrews; Edward F C Blommaart; Alan Sugar; Arthur J Verhoeven; Rolf G Boot; johannes aerts
Characterization of human phagocyte-derived chitotriosidase, a component of innate immunity.
International immunology 2005;17(11):1505-12.
2005: Mitchell R White; Erika Crouch; Martin van Eijk; Max Hartshorn; Lily Pemberton; Ida Tornoe; Uffe Holmskov; Kevan L Hartshorn
Cooperative anti-influenza activities of respiratory innate immune proteins and neuraminidase inhibitor.
American journal of physiology. Lung cellular and molecular physiology 2005;288(5):L831-40.
2004: Martin van Eijk; Mitchell R White; Joseph J Batenburg; Arie B Vaandrager; Lambert M G van Golde; Henk P Haagsman; Kevan L Hartshorn
Interactions of influenza A virus with sialic acids present on porcine surfactant protein D.
American journal of respiratory cell and molecular biology 2004;30(6):871-9.
2003: Henk P Haagsman; V Herias; Martin van Eijk
Surfactant phospholipids and proteins in lung defence.
Acta pharmacologica Sinica 2003;24(12):1301-3.
2003: Martin van Eijk; Mitchell R White; Erika C Crouch; Joseph J Batenburg; Arie B Vaandrager; Lambert M G van Golde; Henk P Haagsman; Kevan L Hartshorn
Porcine pulmonary collectins show distinct interactions with influenza A viruses: role of the N-linked oligosaccharides in the carbohydrate recognition domain.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(3):1431-40.
2003: Martin van Eijk; Cornelis J F Van Noorden; Cornelis de Groot
Proteinases and their inhibitors in the immune system.
International review of cytology 2003;222():197-236.
2002: Martin van Eijk; Chris H A van de Lest; Joseph J Batenburg; Arie B Vaandrager; Joseph Meschi; Kevan L Hartshorn; Lambert M G van Golde; Henk P Haagsman
Porcine surfactant protein D is N-glycosylated in its carbohydrate recognition domain and is assembled into differently charged oligomers.
American journal of respiratory cell and molecular biology 2002;26(6):739-47.
2001: Martin van Eijk; Thierry Defrance; Anca Hennino; Cornelis de Groot
Death-receptor contribution to the germinal-center reaction.
Trends in immunology 2001;22(12):677-82.
2001: J Koenraad van de Wetering; Martin van Eijk; Lambert M G van Golde; Thomas Hartung; Jos van Strijp; Joseph J Batenburg
Characteristics of surfactant protein A and D binding to lipoteichoic acid and peptidoglycan, 2 major cell wall components of gram-positive bacteria.
The Journal of infectious diseases 2001;184(9):1143-51.
2001: Martin van Eijk; Jan Paul Medema; Cornelis de Groot
Cutting edge: cellular Fas-associated death domain-like IL-1-converting enzyme-inhibitory protein protects germinal center B cells from apoptosis during germinal center reactions.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(11):6473-6.
2001: Martin van Eijk; NA de Haan; Claire Rogel-Gaillard; carla zijlstra; PR Lawson; Anneke A Bosma
Assignment of surfactant protein A (SFTPA) and surfactant protein D (SFTPD) to pig chromosome band 14q25-->q26 by in situ hybridization.
Cytogenetics and cell genetics 2001;95(1-2):114-5.
2000: F Danlois; S Zaltash; Jan Johansson; Bengt Robertson; Henk P Haagsman; Martin van Eijk; M F Beers; Frédéric Rollin; Jean-Marie Ruysschaert; G Vandenbussche
Very low surfactant protein C contents in newborn Belgian White and Blue calves with respiratory distress syndrome.
The Biochemical journal 2000;351 Pt 3():779-87.
2000: P Kaliński; Hermelijn H Smits; Joost Schuitemaker; Pedro L Vieira; Martin van Eijk; Esther C de Jong; Eddy A Wierenga; Martien L Kapsenberg
IL-4 is a mediator of IL-12p70 induction by human Th2 cells: reversal of polarized Th2 phenotype by dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(4):1877-81.
2000: K Denzer; Martin van Eijk; Monique J Kleijmeer; E Jakobson; Cornelis de Groot; Hans J Geuze
Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(3):1259-65.
2000: Martin van Eijk; Henk P Haagsman; T Skinner; A Archibald; Kenneth B M Reid; PR Lawson; A Archibold
Porcine lung surfactant protein D: complementary DNA cloning, chromosomal localization, and tissue distribution.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1442-50.
1999: Martin van Eijk; Cornelis de Groot
Germinal center B cell apoptosis requires both caspase and cathepsin activity.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(5):2478-82.
1999: BA Van Rozendaal; Chris H A van de Lest; Martin van Eijk; Lambert M G van Golde; WF Voorhout; Herman P M Van Helden; Henk P Haagsman
Aerosolized endotoxin is immediately bound by pulmonary surfactant protein D in vivo.
Biochimica et biophysica acta 1999;1454(3):261-9.
1999: E Lindhout; Martin van Eijk; Melissa van Pel; Jan Lindeman; Huibert J Dinant; Cornelis de Groot
Fibroblast-like synoviocytes from rheumatoid arthritis patients have intrinsic properties of follicular dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(10):5949-56.
1999: Günther Putz; Monika Walch; Martin van Eijk; Henk P Haagsman
Hydrophobic lung surfactant proteins B and C remain associated with surface film during dynamic cyclic area changes.
Biochimica et biophysica acta 1999;1453(1):126-34.
1998: Günther Putz; Monika Walch; Martin van Eijk; Henk P Haagsman
A spreading technique for forming film in a captive bubble.
Biophysical journal 1998;75(5):2229-39.
1997: BA Van Rozendaal; Chris H A van de Lest; Martin van Eijk; Herman P M Van Helden; Henk P Haagsman
Pulmonary surfactant proteins A and D are involved in the early response to intratracheally aerosolized lipopolysaccharide.
Biochemical Society transactions 1997;25(4):S656.
1997: Wolfgang Bernhard; H P Haagsman; Thomas Tschernig; Christian F Poets; Anthony D Postle; Martin van Eijk; Horst von der Hardt
Conductive airway surfactant: surface-tension function, biochemical composition, and possible alveolar origin.
American journal of respiratory cell and molecular biology 1997;17(1):41-50.
1997: Herman P M Van Helden; Willem C Kuijpers; D Steenvoorden; C Go; Pieter L B Bruijnzeel; Martin van Eijk; Henk P Haagsman
Intratracheal aerosolization of endotoxin (LPS) in the rat: a comprehensive animal model to study adult (acute) respiratory distress syndrome.
Experimental lung research 1997;23(4):297-316.
1996: M Zanotti; G Poli; Wilma Ponti; M Polli; Mariano Rocchi; E Bolzani; M Longeri; S Russo; Harris Lewin; Martin van Eijk
Association of BoLA class II haplotypes with subclinical progression of bovine leukaemia virus infection in Holstein-Friesian cattle.
Animal genetics 1996;27(5):337-41.
1996: H T A Van Tol; Martin van Eijk; C L Mummery; Robert van den Hurk; Mart M Bevers
Influence of FSH and hCG on the resumption of meiosis of bovine oocytes surrounded by cumulus cells connected to membrana granulosa.
Molecular reproduction and development 1996;45(2):218-24.
1996: Martin van Eijk; J Mandelbaum; J Salat-Baroux; J Belaisch-Allart; M Plachot; A M Junca; C L Mummery
Expression of leukaemia inhibitory factor receptor subunits LIFR beta and gp130 in human oocytes and preimplantation embryos.
Molecular human reproduction 1996;2(5):355-60.
1995: Martin van Eijk; C G De Haas; Henk P Haagsman
Quantitative analysis of pulmonary surfactant proteins B and C.
Analytical biochemistry 1995;232(2):231-7.
1995: TW Vahlenkamp; Herman F Egberink; Martin van Eijk; A M Slotboom-Kamphorst; E J Verschoor; Marian C Horzinek; Anthony de Ronde
Competitive reverse transcription-polymerase chain reaction for quantitation of feline immunodeficiency virus.
Journal of virological methods 1995;52(3):335-46.
1995: TW Vahlenkamp; Anthony de Ronde; J Balzarini; L Naesens; E De Clercq; Martin van Eijk; Marian C Horzinek; Herman F Egberink
(R)-9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine is a potent inhibitor of feline immunodeficiency virus infection.
Antimicrobial agents and chemotherapy 1995;39(3):746-9.
1995: Martin van Eijk; Jonathan E Beever; Yang Da; J A Stewart; G E Nicholaides; C A Green; Harris Lewin
Genetic mapping of BoLA-A, CYP21, DRB3, DYA, and PRL on BTA23.
Mammalian genome : official journal of the International Mammalian Genome Society 1995;6(2):151-2.
1995: D Shalhevet; Yang Da; Jonathan E Beever; Martin van Eijk; R Ma; Harris Lewin; H. Rex Gaskins
Genetic mapping of the LMP2 proteasome subunit gene to the BoLA class IIb region.
Immunogenetics 1995;41(1):44-6.
1994: C J Davies; I Joosten; L Andersson; M A Arriens; D Bernoco; B Bissumbhar; G Byrns; Martin van Eijk; B Kristensen; Harris Lewin
Polymorphism of bovine MHC class II genes. Joint report of the Fifth International Bovine Lymphocyte Antigen (BoLA) Workshop, Interlaken, Switzerland, 1 August 1992.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 1994;21(4):259-89.
1993: A Xu; Martin van Eijk; C Park; Harris Lewin
Polymorphism in BoLA-DRB3 exon 2 correlates with resistance to persistent lymphocytosis caused by bovine leukemia virus.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(12):6977-85.
1993: Martin van Eijk; I Russ; Harris Lewin
Order of bovine DRB3, DYA, and PRL determined by sperm typing.
Mammalian genome : official journal of the International Mammalian Genome Society 1993;4(2):113-8.
1992: Marja A Oosterlaken-Dijksterhuis; Martin van Eijk; Lambert M G van Golde; Henk P Haagsman
Lipid mixing is mediated by the hydrophobic surfactant protein SP-B but not by SP-C.
Biochimica et biophysica acta 1992;1110(1):45-50.
1992: Harris Lewin; K Schmitt; R Hubert; Martin van Eijk; Norman Arnheim
Close linkage between bovine prolactin and BoLA-DRB3 genes: genetic mapping in cattle by single sperm typing.
Genomics 1992;13(1):44-8.
1992: Martin van Eijk; J A Stewart-Haynes; Jonathan E Beever; R L Fernando; Harris Lewin
Development of persistent lymphocytosis in cattle is closely associated with DRB2.
Immunogenetics 1992;37(1):64-8.
1992: Martin van Eijk; I Russ; Jonathan E Beever; Harris Lewin
Polymorphism in exon 2 of the bovine lymphocyte antigen (BoLA)-DYA gene.
Animal genetics 1992;23(5):476.
1992: Martin van Eijk; J A Stewart-Haynes; Harris Lewin
Extensive polymorphism of the BoLA-DRB3 gene distinguished by PCR-RFLP.
Animal genetics 1992;23(6):483-96.
1991: Marja A Oosterlaken-Dijksterhuis; Martin van Eijk; B L van Buel; Lambert M G van Golde; Henk P Haagsman
Surfactant protein composition of lamellar bodies isolated from rat lung.
The Biochemical journal 1991;274 ( Pt 1)():115-9.