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Peter van Endert

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Physiology

Antigen Presentation

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Loredana Saveanu; Joël Babdor; Myriam Lawand; Peter van Endert
Insulin-regulated aminopeptidase and its compartment in dendritic cells.
Yuting Ma; Isabelle Martins; Stephen R Mattarollo; Laurie Menger; Mickaël Michaud; João Paulo Portela Catani; Frederic Schlemmer; Mark J Smyth; Eric Solary; Kim Steegh; Abdul Qader Sukkurwala; Philip R Taylor; Erika Vacchelli; Peter van Endert; Takahiro Yamazaki; Heng Yang; Laurence Zitvogel; Sandy Adjemian; Laetitia Aymeric; Nathalie Droin; Helene Duret; Lorenzo Galluzzi; Siamon Gordon; Dalil Hannani; Oliver Kepp; Roman Krzysiek; Guido Kroemer
Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells.
Jan P Böttcher; Dirk H Busch; Svenja Debey-Pascher; Linda Diehl; Jessica Grell; Silke Hegenbarth; Bastian Höchst; Waldemar Kolanus; Christian Kurts; Andreas Limmer; Markus F Neurath; Oliver Schanz; Edgar Schmitt; Joachim L Schultze; Andrea Staratschek-Jox; Peter van Endert; Dirk Wohlleber; Zeinab Abdullah; Imke Atreya; Percy A Knolle
Liver-primed memory T cells generated under noninflammatory conditions provide anti-infectious immunity.

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All Publications

2013: Loredana Saveanu; Joël Babdor; Myriam Lawand; Peter van Endert
Insulin-regulated aminopeptidase and its compartment in dendritic cells.
Molecular immunology 2013;55(2):153-5.
2013: Yuting Ma; Isabelle Martins; Stephen R Mattarollo; Laurie Menger; Mickaël Michaud; João Paulo Portela Catani; Frederic Schlemmer; Mark J Smyth; Eric Solary; Kim Steegh; Abdul Qader Sukkurwala; Philip R Taylor; Erika Vacchelli; Peter van Endert; Takahiro Yamazaki; Heng Yang; Laurence Zitvogel; Sandy Adjemian; Laetitia Aymeric; Nathalie Droin; Helene Duret; Lorenzo Galluzzi; Siamon Gordon; Dalil Hannani; Oliver Kepp; Roman Krzysiek; Guido Kroemer
Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells.
Immunity 2013;38(4):729-41.
2013: Jan P Böttcher; Dirk H Busch; Svenja Debey-Pascher; Linda Diehl; Jessica Grell; Silke Hegenbarth; Bastian Höchst; Waldemar Kolanus; Christian Kurts; Andreas Limmer; Markus F Neurath; Oliver Schanz; Edgar Schmitt; Joachim L Schultze; Andrea Staratschek-Jox; Peter van Endert; Dirk Wohlleber; Zeinab Abdullah; Imke Atreya; Percy A Knolle
Liver-primed memory T cells generated under noninflammatory conditions provide anti-infectious immunity.
Cell reports 2013;3(3):779-95.
2013: Mirjana Weimershaus; Irini Evnouchidou; Loredana Saveanu; Peter van Endert
Peptidases trimming MHC class I ligands.
Current opinion in immunology 2013;25(1):90-6.
2013: Loredana Saveanu; Peter van Endert
Preparing antigens suitable for cross-presentation assays in vitro and in vivo.
Methods in molecular biology (Clifton, N.J.) 2013;960():389-400.
2013: Mirjana Weimershaus; Peter van Endert
Preparation of dendritic cells by in vitro cultures.
Methods in molecular biology (Clifton, N.J.) 2013;960():351-7.
2012: Émmanuelle Énée; Jean-Baptiste Arnoux; Emilie Barilleau; Jacques Beltrand; Lucienne Chatenoud; Yamina Hamel; Roland Kratzer; Christophe Marchi; Bénédicte Michaud; Jean-Jacques Robert; Peter van Endert
ZnT8 is a major CD8+ T cell-recognized autoantigen in pediatric type 1 diabetes.
Diabetes 2012;61(7):1779-84.
2012: Mirjana Weimershaus; Bénédicte Manoury; Sophia Maschalidi; Fernando Sepulveda; Peter van Endert; Loredana Saveanu
Conventional dendritic cells require IRAP-Rab14 endosomes for efficient cross-presentation.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(4):1840-6.
2012: Sophia Maschalidi; Fernando E Sepulveda; Mustapha Si-Tahar; Mira Tohme; Peter van Endert; Fany Blanc; Michel Chignard; Delphyne Descamps; Signe Hässler; Bénédicte Manoury
Asparagine endopeptidase controls anti-influenza virus immune responses through TLR7 activation.
PLoS pathogens 2012;8(8):e1002841.
2012: Loredana Saveanu; Peter van Endert
The role of insulin-regulated aminopeptidase in MHC class I antigen presentation.
Frontiers in immunology 2012;3():57.
2011: Nawel Merzougui; Loredana Saveanu; Roland Kratzer; Peter van Endert
A proteasome-dependent, TAP-independent pathway for cross-presentation of phagocytosed antigen.
EMBO reports 2011;12(12):1257-64.
2011: P M Saunders; Peter van Endert
Running the gauntlet: from peptide generation to antigen presentation by MHC class I.
Tissue antigens 2011;78(3):161-70.
2011: Sylvain Cardinaud; Gesa Consiglieri; Romain Bouziat; Alejandra Urrutia; Stéphanie Graff-Dubois; Slim Fourati; Isabelle Malet; Julien Guergnon; Amélie Guihot; Christine Katlama; Brigitte Autran; Peter van Endert; François A Lemonnier; Victor Appay; Olivier Schwartz; Peter M Kloetzel; Arnaud Moris
CTL escape mediated by proteasomal destruction of an HIV-1 cryptic epitope.
PLoS pathogens 2011;7(5):e1002049.
2011: Peter van Endert
Post-proteasomal and proteasome-independent generation of MHC class I ligands.
Cellular and molecular life sciences : CMLS 2011;68(9):1553-67.
2011: Peter van Endert
Providing ligands for MHC class I molecules.
Cellular and molecular life sciences : CMLS 2011;68(9):1467-9.
2011: Chantal Kuhn; Sylvaine You; Fabrice Valette; Geoff Hale; Peter van Endert; Jean-François Bach; Herman Waldmann; Lucienne Chatenoud
Human CD3 transgenic mice: preclinical testing of antibodies promoting immune tolerance.
Science translational medicine 2011;3(68):68ra10.
2010: Esther Ghanem; Susanne Fritzsche; Mohammed Al-Balushi; Jood Hashem; Lana Ghuneim; Lena Thomer; Hubert Kalbacher; Peter van Endert; Emmanuel Wiertz; Robert Tampé; Sebastian Springer
The transporter associated with antigen processing (TAP) is active in a post-ER compartment.
Journal of cell science 2010;123(Pt 24):4271-9.
2010: Oliver Kepp; Abdelaziz Gdoura; Isabelle Martins; Theocharis Panaretakis; Frederic Schlemmer; Antoine Tesniere; Gian Maria Fimia; Fabiola Ciccosanti; Anne Burgevin; Mauro Piacentini; Paul Eggleton; Philip J Young; Laurence Zitvogel; Peter van Endert; Guido Kroemer
Lysyl tRNA synthetase is required for the translocation of calreticulin to the cell surface in immunogenic death.
Cell cycle (Georgetown, Tex.) 2010;9(15):3072-7.
2010: Esther Kamphausen; Christiane Kellert; Tarish Abbas; Nadja Akkad; Stefan Tenzer; Graham Pawelec; Hansjoerg Schild; Peter van Endert; Barbara Seliger
Distinct molecular mechanisms leading to deficient expression of ER-resident aminopeptidases in melanoma.
Cancer immunology, immunotherapy : CII 2010;59(8):1273-84.
2010: Roland Kratzer; François-Xavier Mauvais; Anne Burgevin; Emilie Barilleau; Peter van Endert
Fusion proteins for versatile antigen targeting to cell surface receptors reveal differential capacity to prime immune responses.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(12):6855-64.
2010: Nicolas Parmentier; Vincent Stroobant; Didier Colau; Philippe de Diesbach; Sandra Morel; Jacques Chapiro; Peter van Endert; Benoît J Van den Eynde
Production of an antigenic peptide by insulin-degrading enzyme.
Nature immunology 2010;11(5):449-54.
2010: Avital Lev; Michael F Princiotta; Damian Zanker; Kazuyo Takeda; James S Gibbs; Chiharu Kumagai; Elizabeth Waffarn; Brian P Dolan; Anne Burgevin; Peter van Endert; Weisan Chen; Jack R Bennink; Jonathan W Yewdell
Compartmentalized MHC class I antigen processing enhances immunosurveillance by circumventing the law of mass action.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(15):6964-9.
2010: Antoine Tesniere; F Schlemmer; V Boige; O Kepp; I Martins; François Ghiringhelli; L Aymeric; M Michaud; Lionel Apetoh; L Barault; J Mendiboure; J-P Pignon; V Jooste; Peter van Endert; M Ducreux; Laurence Zitvogel; F Piard; Guido Kroemer
Immunogenic death of colon cancer cells treated with oxaliplatin.
Oncogene 2010;29(4):482-91.
2010: Anna Moser; Hsiang-Ting Hsu; Peter van Endert
Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets.
F1000 biology reports 2010;2():75.
2009: Peter van Endert
Toll-like receptor 9: AEP takes control.
Immunity 2009;31(5):696-8.
2009: Francesca Fallarino; Giovanni Luca; Mario Calvitti; Francesco Mancuso; Claudio Nastruzzi; Maria C Fioretti; Ursula Grohmann; ennio becchetti; Anne Burgevin; Roland Kratzer; Peter van Endert; Louis Boon; Paolo Puccetti; Riccardo Calafiore
Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone.
The Journal of experimental medicine 2009;206(11):2511-26.
2009: Sylvain Cardinaud; Romain Bouziat; Pierre-Simon Rohrlich; sophie tourdot; Laurence Weiss; Pierre Langlade-Demoyen; Anne Burgevin; Susana Fiorentino; Peter van Endert; François A Lemonnier
Design of a HIV-1-derived HLA-B07.02-restricted polyepitope construct.
AIDS (London, England) 2009;23(15):1945-54.
2009: Loredana Saveanu; Oliver Carroll; Mirjana Weimershaus; Pierre Guermonprez; Elke Firat; Vivian Lindo; Fiona Greer; Jean Davoust; Roland Kratzer; Susanna R Keller; Gabriele Niedermann; Peter van Endert
IRAP identifies an endosomal compartment required for MHC class I cross-presentation.
Science (New York, N.Y.) 2009;325(5937):213-7.
2009: Stefan Tenzer; Edmund Wee; Anne Burgevin; Guillaume Stewart-Jones; Lone Friis; Kasper Lamberth; Chih-hao Chang; Mikkel Harndahl; Mirjana Weimershaus; Jan Gerstoft; Nadja Akkad; Paul Klenerman; Lars Fugger; E Yvonne Jones; Andrew J McMichael; Søren Buus; Hansjörg Schild; Peter van Endert; Astrid K N Iversen
Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance.
Nature immunology 2009;10(6):636-46.
2009: Sarah Nicholls; Karen P Piper; Fiyaz Mohammed; Timothy R Dafforn; Stefan Tenzer; Mahboob Salim; Premini Mahendra; Charles Craddock; Peter van Endert; Hansjörg Schild; Mark Cobbold; Victor H Engelhard; Paul A H Moss; Benjamin E Willcox
Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(10):3889-94.
2009: Theocharis Panaretakis; Oliver Kepp; Ulf Brockmeier; Antoine Tesniere; Ann-Charlotte Bjorklund; Daniel C Chapman; Michael Durchschlag; Nicholas Joza; Gérard Pierron; Peter van Endert; Junying Yuan; Laurence Zitvogel; Frank Madeo; David B Williams; Guido Kroemer
Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death.
The EMBO journal 2009;28(5):578-90.
2008: Theocharis Panaretakis; Nicholas Joza; Nazanine Modjtahedi; Antoine Tesniere; Ilio Vitale; M Durchschlag; Gian Maria Fimia; O Kepp; Mauro Piacentini; K-U Froehlich; Peter van Endert; Laurence Zitvogel; Frank Madeo; Guido Kroemer
The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death.
Cell death and differentiation 2008;15(9):1499-509.
2008: Doriana Fruci; Patrizio Giacomini; Maria Rita Nicotra; Matteo Forloni; Rocco Fraioli; Loredana Saveanu; Peter van Endert; Pier Giorgio Natali
Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non-lymphoid human tissues.
Journal of cellular physiology 2008;216(3):742-9.
2008: Andreas O Weinzierl; Despina Rudolf; Nina Hillen; Stefan Tenzer; Peter van Endert; Hansjörg Schild; Hans-Georg Rammensee; Stefan Stevanović
Features of TAP-independent MHC class I ligands revealed by quantitative mass spectrometry.
European journal of immunology 2008;38(6):1503-10.
2008: Emanuela Martinuzzi; Giulia Novelli; Matthieu Scotto; Philippe Blancou; Jean-Marie Bach; Lucy Chaillous; Graziella Bruno; Lucienne Chatenoud; Peter van Endert; Roberto Mallone
The frequency and immunodominance of islet-specific CD8+ T-cell responses change after type 1 diabetes diagnosis and treatment.
Diabetes 2008;57(5):1312-20.
2008: Emanuela Martinuzzi; Matthieu Scotto; Emmanuelle Enée; Vedran Brezar; Jean-Antoine Ribeil; Peter van Endert; Roberto Mallone
Serum-free culture medium and IL-7 costimulation increase the sensitivity of ELISpot detection.
Journal of immunological methods 2008;333(1-2):61-70.
2008: Emmanuelle Enée; Emanuela Martinuzzi; Philippe Blancou; Jean-Marie Bach; Roberto Mallone; Peter van Endert
Equivalent specificity of peripheral blood and islet-infiltrating CD8+ T lymphocytes in spontaneously diabetic HLA-A2 transgenic NOD mice.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(8):5430-8.
2008: Roberto Mallone; Peter van Endert
T cells in the pathogenesis of type 1 diabetes.
Current diabetes reports 2008;8(2):101-6.
2008: Jisen Huai; Elke Firat; Ahmed Nil; Daniele Million; Simone Gaedicke; Benoit Kanzler; Marina A Freudenberg; Peter van Endert; Gabriele Kohler; Heike L Pahl; Peter Aichele; Klaus Eichmann; Gabriele Niedermann
Activation of cellular death programs associated with immunosenescence-like phenotype in TPPII knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(13):5177-82.
2008: Mark M Schatz; Björn Peters; Nadja Akkad; Nina Ullrich; Alejandra Nacarino Martinez; Oliver Carroll; Sascha Bulik; Hans-Georg Rammensee; Peter van Endert; Hermann-Georg Holzhütter; Stefan Tenzer; Hansjörg Schild
Characterizing the N-terminal processing motif of MHC class I ligands.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(5):3210-7.
2008: Anne Burgevin; Loredana Saveanu; Yohan Kim; Emilie Barilleau; Maya Kotturi; Alessandro Sette; Peter van Endert; Bjoern Peters
A detailed analysis of the murine TAP transporter substrate specificity.
PloS one 2008;3(6):e2402.
2007: Elke Firat; Jisen Huai; Loredana Saveanu; Simone Gaedicke; Peter Aichele; Klaus Eichmann; Peter van Endert; Gabriele Niedermann
Analysis of direct and cross-presentation of antigens in TPPII knockout mice.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(12):8137-45.
2007: Michel Obeid; Antoine Tesniere; Theocharis Panaretakis; Roberta Tufi; Nick Joza; Peter van Endert; François Ghiringhelli; Lionel Apetoh; Nathalie Chaput; Caroline Flament; Evelyn Ullrich; Stéphane de Botton; Laurence Zitvogel; Guido Kroemer
Ecto-calreticulin in immunogenic chemotherapy.
Immunological reviews 2007;220():22-34.
2007: Michel Obeid; Theocharis Panaretakis; Nick Joza; Roberta Tufi; Antoine Tesniere; Peter van Endert; Laurence Zitvogel; Guido Kroemer
Calreticulin exposure is required for the immunogenicity of gamma-irradiation and UVC light-induced apoptosis.
Cell death and differentiation 2007;14(10):1848-50.
2007: Philippe Blancou; Roberto Mallone; Emanuela Martinuzzi; Sabine Sévère; Sylvie Pogu; Giulia Novelli; Graziella Bruno; Bernard Charbonnel; Manuel Dolz; Lucy Chaillous; Peter van Endert; Jean-Marie Bach
Immunization of HLA class I transgenic mice identifies autoantigenic epitopes eliciting dominant responses in type 1 diabetes patients.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(11):7458-66.
2007: Roberto Mallone; Emanuela Martinuzzi; Philippe Blancou; Giulia Novelli; Georgia Afonso; Manuel Dolz; Graziella Bruno; Lucy Chaillous; Lucienne Chatenoud; Jean-Marie Bach; Peter van Endert
CD8+ T-cell responses identify beta-cell autoimmunity in human type 1 diabetes.
Diabetes 2007;56(3):613-21.
2007: Elke Firat; Loredana Saveanu; Peter Aichele; Peter Staeheli; Jisen Huai; Simone Gaedicke; Ahmed Nil; Gilles Besin; Benoît Kanzler; Peter van Endert; Gabriele Niedermann
The role of endoplasmic reticulum-associated aminopeptidase 1 in immunity to infection and in cross-presentation.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(4):2241-8.
2007: Peter van Endert; Jose A Villadangos
Antigen processing and recognition.
Current opinion in immunology 2007;19(1):63-5.
2007: Michel Obeid; Antoine Tesniere; François Ghiringhelli; Gian Maria Fimia; Lionel Apetoh; Jean-Luc PERFETTINI; Maria Castedo; Grégoire Mignot; Theocharis Panaretakis; Noelia Casares; Didier Métivier; Nathanael Larochette; Peter van Endert; Fabiola Ciccosanti; Mauro Piacentini; Laurence Zitvogel; Guido Kroemer
Calreticulin exposure dictates the immunogenicity of cancer cell death.
Nature medicine 2007;13(1):54-61.
2006: Peter van Endert; Yousra Hassainya; Vivian Lindo; Jean-Marie Bach; Philippe Blancou; François Lemonnier; Roberto Mallone
HLA class I epitope discovery in type 1 diabetes.
Annals of the New York Academy of Sciences 2006;1079():190-7.
2006: Peter van Endert
[Processing of MHC class I presented antigens].
Médecine sciences : M/S 2006;22(8-9):727-32.
2006: David Ghez; yves lepelletier; Sophie Lambert; Jean-Marie Fourneau; Vincent Blot; Sébastien Janvier; Bertrand Arnulf; Peter van Endert; Nikolaus Heveker; Claudine Pique; Olivier Hermine
Neuropilin-1 is involved in human T-cell lymphotropic virus type 1 entry.
Journal of virology 2006;80(14):6844-54.
2006: Doriana Fruci; Silvia Ferracuti; Maria Zaira Limongi; Veronica Cunsolo; Ezio Giorda; Rocco Fraioli; Leonardo Sibilio; Oliver Carroll; Akira Hattori; Peter van Endert; Patrizio Giacomini
Expression of endoplasmic reticulum aminopeptidases in EBV-B cell lines from healthy donors and in leukemia/lymphoma, carcinoma, and melanoma cell lines.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(8):4869-79.
2006: Yolanda Samino; Daniel López; Sara Guil; Loredana Saveanu; Peter van Endert; Margarita Del-Val
A long N-terminal-extended nested set of abundant and antigenic major histocompatibility complex class I natural ligands from HIV envelope protein.
The Journal of biological chemistry 2006;281(10):6358-65.
2006: Soraya Abouzahr; Georges Bismuth; Catherine Gaudin; Oliver Caroll; Peter van Endert; Abdelali JALIL; Jean Dausset; Isabelle Vergnon; Catherine Richon; Audrey Kauffmann; Jérôme Galon; Graça Raposo; Fathia Mami-Chouaib; Salem Chouaib
Identification of target actin content and polymerization status as a mechanism of tumor resistance after cytolytic T lymphocyte pressure.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(5):1428-33.
2005: Loredana Saveanu; Oliver Carroll; Yousra Hassainya; Peter van Endert
Complexity, contradictions, and conundrums: studying post-proteasomal proteolysis in HLA class I antigen presentation.
Immunological reviews 2005;207():42-59.
2005: Yousra Hassainya; Francisco Garcia-Pons; Roland Kratzer; Vivian Lindo; Fiona Greer; François A Lemonnier; Gabriele Niedermann; Peter van Endert
Identification of naturally processed HLA-A2--restricted proinsulin epitopes by reverse immunology.
Diabetes 2005;54(7):2053-9.
2005: Loredana Saveanu; Oliver Carroll; Vivian Lindo; Margarita Del-Val; DANIEL LOPEZ; yves lepelletier; Fiona Greer; Lutz Schomburg; Doriana Fruci; Gabriele Niedermann; Peter van Endert
Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.
Nature immunology 2005;6(7):689-97.
2005: Loredana Saveanu; Peter van Endert
Dendritic cells: open for presentation business.
Nature immunology 2005;6(1):7-8.
2004: Slobodan Culina; Gregoire Lauvau; Brigitte Gubler; Peter van Endert
Calreticulin promotes folding of functional human leukocyte antigen class I molecules in vitro.
The Journal of biological chemistry 2004;279(52):54210-5.
2004: Stuart I Mannering; Jessica S Morris; Natalie L Stone; Kent P Jensen; Peter van Endert; Leonard C Harrison
CD4+ T cell proliferation in response to GAD and proinsulin in healthy, pre-diabetic, and diabetic donors.
Annals of the New York Academy of Sciences 2004;1037():16-21.
2004: Fabrice Lemaître; Manuelle Viguier; Min-Sun Cho; Jean-Marie Fourneau; Bernard Maillère; Philippe Kourilsky; Peter van Endert; Laurent Ferradini
Detection of low-frequency human antigen-specific CD4(+) T cells using MHC class II multimer bead sorting and immunoscope analysis.
European journal of immunology 2004;34(10):2941-9.
2004: Mariette Lisbonne; Patricia Hachem; Marie-Béatrice Tonanny; Jean-Marie Fourneau; Stephane Sidobre; Mitchell Kronenberg; Peter van Endert; Michel Dy; Elke Schneider; Maria C Leite-de-Moraes
In vivo activation of invariant V alpha 14 natural killer T cells by alpha-galactosylceramide sequentially induces Fas-dependent and -independent cytotoxicity.
European journal of immunology 2004;34(5):1381-8.
2004: Jean-Marie Fourneau; Hélène Cohen; Peter van Endert
A chaperone-assisted high yield system for the production of HLA-DR4 tetramers in insect cells.
Journal of immunological methods 2004;285(2):253-64.
2004: Jean-Marie Fourneau; Jean-Marie Bach; Peter van Endert; Jean-François Bach
The elusive case for a role of mimicry in autoimmune diseases.
Molecular immunology 2004;40(14-15):1095-102.
2004: Beatriz C Gil-Torregrosa; Ana-Maria Lennon-Duménil; Benedikt Kessler; Pierre Guermonprez; Hidde L Ploegh; Doriana Fruci; Peter van Endert; Sebastian Amigorena
Control of cross-presentation during dendritic cell maturation.
European journal of immunology 2004;34(2):398-407.
2003: Stuart I Mannering; Jessica S Morris; Kent P Jensen; Anthony W Purcell; Margo Honeyman; Peter van Endert; Leonard C Harrison
A sensitive method for detecting proliferation of rare autoantigen-specific human T cells.
Journal of immunological methods 2003;283(1-2):173-83.
2003: Pierre Guermonprez; Loredana Saveanu; Monique J Kleijmeer; Jean Davoust; Peter van Endert; Sebastian Amigorena
ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells.
Nature 2003;425(6956):397-402.
2003: Björn Peters; Sascha Bulik; Robert Tampe; Peter van Endert; Hermann-Georg Holzhütter
Identifying MHC class I epitopes by predicting the TAP transport efficiency of epitope precursors.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(4):1741-9.
2003: Mariette Lisbonne; Séverine Diem; Alexandre de Castro Keller; Jean Lefort; Luiza M Araujo; Patricia Hachem; Jean-Marie Fourneau; Stéphane Sidobre; Mitchell Kronenberg; Masuru Taniguchi; Peter van Endert; Michel Dy; Philip W Askenase; Momtchilo Russo; B Boris Vargaftig; André Herbelin; Maria C Leite-de-Moraes
Cutting edge: invariant V alpha 14 NKT cells are required for allergen-induced airway inflammation and hyperreactivity in an experimental asthma model.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(4):1637-41.
2003: Maria Lucchiari-Hartz; Viv Lindo; Niclas Hitziger; Simone Gaedicke; Loredana Saveanu; Peter van Endert; Fiona Greer; Klaus Eichmann; Gabriele Niedermann
Differential proteasomal processing of hydrophobic and hydrophilic protein regions: contribution to cytotoxic T lymphocyte epitope clustering in HIV-1-Nef.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(13):7755-60.
2003: Doriana Fruci; Gregoire Lauvau; Loredana Saveanu; Massimo Amicosante; Richard H Butler; Axel Polack; Ginhoux Florent; François Lemonnier; Hueseyin Firat; Peter van Endert
Quantifying recruitment of cytosolic peptides for HLA class I presentation: impact of TAP transport.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(6):2977-84.
2002: William Cohen; A Bianco; Francine Connan; Luc Camoin; Marc Dalod; Gregoire Lauvau; E Ferriès; B Culmann-Penciolelli; Peter van Endert; Jean-Paul Briand; Jeannine Choppin; Jean-Gérard Guillet
Study of antigen-processing steps reveals preferences explaining differential biological outcomes of two HLA-A2-restricted immunodominant epitopes from human immunodeficiency virus type 1.
Journal of virology 2002;76(20):10219-25.
2002: Loredana Saveanu; Doriana Fruci; Peter van Endert
Beyond the proteasome: trimming, degradation and generation of MHC class I ligands by auxiliary proteases.
Molecular immunology 2002;39(3-4):203-15.
2002: Peter van Endert; Loredana Saveanu; Eric W Hewitt; Paul Lehner
Powering the peptide pump: TAP crosstalk with energetic nucleotides.
Trends in biochemical sciences 2002;27(9):454-61.
2001: Heth R Turnquist; Shanna E Vargas; Adrian Reber; Mary M McIlhaney; S Li; P Wang; Sam D Sanderson; B Gubler; Peter van Endert; Joyce C Solheim
A region of tapasin that affects L(d) binding and assembly.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(8):4443-9.
2001: Doriana Fruci; Gabriele Niedermann; Richard H Butler; Peter van Endert
Efficient MHC class I-independent amino-terminal trimming of epitope precursor peptides in the endoplasmic reticulum.
Immunity 2001;15(3):467-76.
2001: Loredana Saveanu; S Daniel; Peter van Endert
Distinct functions of the ATP binding cassettes of transporters associated with antigen processing: a mutational analysis of Walker A and B sequences.
The Journal of biological chemistry 2001;276(25):22107-13.
2001: Loredana Saveanu; Peter van Endert
Regulation of transporters associated with antigen processing (TAPs) by nucleotide binding to, and hydrolysis by, Walker consensus sequences.
Advances in experimental medicine and biology 2001;495():79-82.
2000: D B De Oliveira; E Harfouch-Hammoud; H Otto; Nikolaos Papandreou; Lawrence J Stern; H Cohen; B O Boehm; J Bach; S Caillat-Zucman; T Walk; G Jung; Elias Eliopoulos; George K Papadopoulos; Peter van Endert
Structural analysis of two HLA-DR-presented autoantigenic epitopes: crucial role of peripheral but not central peptide residues for T-cell receptor recognition.
Molecular immunology 2000;37(14):813-25.
2000: Maria Lucchiari-Hartz; Peter van Endert; Gregoire Lauvau; R Maier; Andreas Meyerhans; D Mann; Klaus Eichmann; Gabriele Niedermann
Cytotoxic T lymphocyte epitopes of HIV-1 Nef: Generation of multiple definitive major histocompatibility complex class I ligands by proteasomes.
The Journal of experimental medicine 2000;191(2):239-52.
1999: Gregoire Lauvau; K Kakimi; Gabriele Niedermann; M Ostankovitch; Patricia Yotnda; Hueseyin Firat; F V Chisari; Peter van Endert
Human transporters associated with antigen processing (TAPs) select epitope precursor peptides for processing in the endoplasmic reticulum and presentation to T cells.
The Journal of experimental medicine 1999;190(9):1227-40.
1999: Gregoire Lauvau; Brigitte Gubler; H Cohen; S Daniel; S Caillat-Zucman; Peter van Endert
Tapasin enhances assembly of transporters associated with antigen processing-dependent and -independent peptides with HLA-A2 and HLA-B27 expressed in insect cells.
The Journal of biological chemistry 1999;274(44):31349-58.
1999: E Harfouch-Hammoud; T Walk; H Otto; G Jung; Jean-François Bach; Peter van Endert; Sophie Caillat-Zucman
Identification of peptides from autoantigens GAD65 and IA-2 that bind to HLA class II molecules predisposing to or protecting from type 1 diabetes.
Diabetes 1999;48(10):1937-47.
1999: Peter van Endert
Role of nucleotides and peptide substrate for stability and functional state of the human ABC family transporters associated with antigen processing.
The Journal of biological chemistry 1999;274(21):14632-8.
1998: Katharina Fleischhauer; Luca Gattinoni; P Dalerba; Gregoire Lauvau; E Zanaria; B Dabovic; Peter van Endert; Claudio Bordignon; Catia Traversari
The DAM gene family encodes a new group of tumor-specific antigens recognized by human leukocyte antigen A2-restricted cytotoxic T lymphocytes.
Cancer research 1998;58(14):2969-72.
1998: S Daniel; Vladimir Brusic; Sophie Caillat-Zucman; Nikolai Petrovsky; L Harrison; D Riganelli; Francesco Sinigaglia; F Gallazzi; Juergen Hammer; Peter van Endert
Relationship between peptide selectivities of human transporters associated with antigen processing and HLA class I molecules.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(2):617-24.
1998: Brigitte Gubler; S Daniel; E A Armandola; J Hammer; S Caillat-Zucman; Peter van Endert
Substrate selection by transporters associated with antigen processing occurs during peptide binding to TAP.
Molecular immunology 1998;35(8):427-33.
1998: Jean-Marie Bach; H Otto; G Jung; H Cohen; Christian Boitard; Jean-François Bach; Peter van Endert
Identification of mimicry peptides based on sequential motifs of epitopes derived from 65-kDa glutamic acid decarboxylase.
European journal of immunology 1998;28(6):1902-10.
1998: C A White; Scott A Thomson; L Cooper; Peter van Endert; R Tampe; Barbara E H Coupar; L Qiu; P G Parsons; Denis Moss; Rajiv Khanna
Constitutive transduction of peptide transporter and HLA genes restores antigen processing function and cytotoxic T cell-mediated immune recognition of human melanoma cells.
International journal of cancer. Journal international du cancer 1998;75(4):590-5.
1997: Silvia Tanzarella; Katharina Fleischhauer; Peter van Endert; Claudio Bordignon; Catia Traversari
Characterization of antigenic peptide epitopes by reverse immunology: induction of cytotoxic T lymphocytes specific for exogenous peptide only.
International journal of cancer. Journal international du cancer 1997;72(5):912-5.
1997: S Daniel; Sophie Caillat-Zucman; Juergen Hammer; Jean-François Bach; Peter van Endert
Absence of functional relevance of human transporter associated with antigen processing polymorphism for peptide selection.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(5):2350-7.
1997: Jean-Marie Bach; H Otto; Gerald Nepom; G Jung; H Cohen; J Timsit; Christian Boitard; Peter van Endert
High affinity presentation of an autoantigenic peptide in type I diabetes by an HLA class II protein encoded in a haplotype protecting from disease.
Journal of autoimmunity 1997;10(4):375-86.
1996: Katharina Fleischhauer; Doriana Fruci; Peter van Endert; J Herman; Silvia Tanzarella; H J Wallny; Pierre G Coulie; Claudio Bordignon; Catia Traversari
Characterization of antigenic peptides presented by HLA-B44 molecules on tumor cells expressing the gene MAGE-3.
International journal of cancer. Journal international du cancer 1996;68(5):622-8.
1996: Peter van Endert
Peptide selection for presentation by HLA class I: a role for the human transporter associated with antigen processing?
Immunologic research 1996;15(4):265-79.
1995: Peter van Endert; D Riganelli; G Greco; Katharina Fleischhauer; J Sidney; A Sette; Jean-François Bach
The peptide-binding motif for the human transporter associated with antigen processing.
The Journal of experimental medicine 1995;182(6):1883-95.
1995: M Delamaire; J Timsit; S Caillat-Zucman; Didier Maugendre; H Roussely; Gilbert Semana; A M Yamamoto; Peter van Endert; Christian Boitard; B Genetet
HLA-associated heterogeneity of the humoral response to islet antigens in insulin-dependent diabetes.
Journal of autoimmunity 1995;8(5):645-57.
1995: Klaus J Frueh; K Ahn; Hakim Djaballah; P Sempé; Peter van Endert; Robert Tampé; PA Peterson; Y Yang
A viral inhibitor of peptide transporters for antigen presentation.
Nature 1995;375(6530):415-8.
1994: T H Meyer; Peter van Endert; S Uebel; B Ehring; Robert Tampé
Functional expression and purification of the ABC transporter complex associated with antigen processing (TAP) in insect cells.
FEBS letters 1994;351(3):443-7.
1994: Peter van Endert; Robert Tampé; T H Meyer; Roland Tisch; J F Bach; H O McDevitt
A sequential model for peptide binding and transport by the transporters associated with antigen processing.
Immunity 1994;1(6):491-500.