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Jennifer Van Eyk

Research Profile

Occupations

Proteomics

Chemicals & Drugs

Anatomy

Myocardium

Procedures

Genes & Molecular Sequences

Amino Acid Sequences

Phenomena

Concepts & Ideas

Living Beings

Physiology

Post Translational Protein Processing

Disorders

Heart Failure

Co-author Network

Publications

TOP 3
Zongming Fu; Richard S Vander Heide; David Herrington; Timothy Howard; Zhicheng Jin; Avraham Rosenberg; Grace Athas; Barbara Crain; Allen D Everett; Kun Yan; Jennifer E Van Eyk
Improved protein extraction and protein identification from archival formalin-fixed paraffin-embedded human aortas.
Ronald J Holewinski; Zhicheng Jin; Matthew D Maust; Matthew J Powell; Jennifer E Van Eyk
A fast and reproducible method for albumin isolation and depletion from serum and cerebrospinal fluid.
Jonathan A Kirk; Anne M Murphy; Pingbo Zhang; Jennifer E Van Eyk
Troponin I alterations detected by multiple-reaction monitoring: how might this impact the study of heart failure?

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All Publications

2013: Zongming Fu; Richard S Vander Heide; David Herrington; Timothy Howard; Zhicheng Jin; Avraham Rosenberg; Grace Athas; Barbara Crain; Allen D Everett; Kun Yan; Jennifer E Van Eyk
Improved protein extraction and protein identification from archival formalin-fixed paraffin-embedded human aortas.
Proteomics. Clinical applications 2013;7(3-4):217-24.
2013: Ronald J Holewinski; Zhicheng Jin; Matthew D Maust; Matthew J Powell; Jennifer E Van Eyk
A fast and reproducible method for albumin isolation and depletion from serum and cerebrospinal fluid.
Proteomics 2013;13(5):743-50.
2013: Jonathan A Kirk; Anne M Murphy; Pingbo Zhang; Jennifer E Van Eyk
Troponin I alterations detected by multiple-reaction monitoring: how might this impact the study of heart failure?
Expert review of proteomics 2013;10(1):5-8.
2013: Heaseung S Chung; Christopher I Murray; Vidya Venkatraman; Sheng-Bing Wang; Jennifer E Van Eyk
Cysteine oxidative posttranslational modifications: emerging regulation in the cardiovascular system.
Circulation research 2013;112(2):382-92.
2013: Ruedi Aebersold; Gary D Bader; Aled M Edwards; Martin Kussmann; Jun Qin; Jennifer E Van Eyk; Gilbert S Omenn
The biology/disease-driven human proteome project (B/D-HPP): enabling protein research for the life sciences community.
Journal of proteome research 2013;12(1):23-7.
2013: Miroslava Stastna; Jennifer E Van Eyk
Optimized method for identification of the proteomes secreted by cardiac cells.
Methods in molecular biology (Clifton, N.J.) 2013;1005():225-35.
2013: Eric Grote; Weihua Ji; Xiaoqian Liu; Qin Fu; Jennifer E Van Eyk
Using pure protein to build a multiple reaction monitoring mass spectrometry assay for targeted detection and quantitation.
Methods in molecular biology (Clifton, N.J.) 2013;1005():199-213.
2013: Christopher I Murray; Helge Uhrigshardt; Hea Seung Chung; Jennifer E Van Eyk
Quantification of Mitochondrial S-Nitrosylation by CysTMT(6) Switch Assay.
Methods in molecular biology (Clifton, N.J.) 2013;1005():169-79.
2013: Sheng-Bing Wang; Heaseung S Chung; Christopher I Murray; Jennifer E Van Eyk
Redox regulation of mitochondrial ATP synthase.
Trends in cardiovascular medicine 2013;23(1):14-8.
2012: Miroslava Stastna; Jennifer E Van Eyk
New and emerging technologies for clinical proteomics.
Proteomics. Clinical applications 2012;6(11-12):547.
2012: Christopher I Murray; Jennifer E Van Eyk
A twist on quantification: measuring the site occupancy of S-nitrosylation.
Circulation research 2012;111(10):1253-5.
2012: T S Lancaster; Veronica Lopez; Jennifer E Van Eyk; J Craig Hunter; S J Jefferson; E G Lakatta; D H Korzick
Quantitative proteomic analysis reveals novel mitochondrial targets of estrogen deficiency in the aged female rat heart.
Physiological genomics 2012;44(20):957-69.
2012: Pingbo Zhang; Jennifer E Van Eyk; Cristobal G dos Remedios; Weihua Ji; David A Kass; Jonathan A Kirk; Anne M Murphy
Multiple reaction monitoring to identify site-specific troponin I phosphorylated residues in the failing human heart.
Circulation 2012;126(15):1828-37.
2012: Miroslava Stastna; Jennifer E Van Eyk
Improved and emerging gel-free separation and detection methods for proteomics.
Proteomics 2012;12(19-20):2902-3.
2012: Christopher I Murray; Jennifer E Van Eyk
Chasing cysteine oxidative modifications: proteomic tools for characterizing cysteine redox status.
Circulation. Cardiovascular genetics 2012;5(5):591.
2012: Miroslava Stastna; Jennifer E Van Eyk
Analysis of protein isoforms: can we do it better?
Proteomics 2012;12(19-20):2937-48.
2012: Wei Dong Gao; S Bruce King; Christopher I Murray; Xiaoxu Shen; Brian A Stanley; Ye Tian; Jennifer E Van Eyk; David A Wink; Xin Zhong; Jenna F DuMond; Darren Foster; Nazareno Paolocci
Nitroxyl-mediated disulfide bond formation between cardiac myofilament cysteines enhances contractile function.
Circulation research 2012;111(8):1002-11.
2012: Roz Banks; Jennifer E Van Eyk
Introducing the "personal perspective" series.
Proteomics. Clinical applications 2012;6(7-8):339.
2012: Mark E Lindsay; Geert R Mortier; Loretha Myers; Gretchen Oswald; Dorien Schepers; Janneke Timmermans; Jennifer E Van Eyk; Lut Van Laer; Margaret H Yang; Britt-Marie Anderlid; Djahita Bjeda; Nikhita Ajit Bolar; Ernie M H F Bongers; Alan C Braverman; Han G Brunner; Peter H Byers; Natalie Canham; Yichun Chen; Harry C Dietz; Jefferson J Doyle; Abdallah F Elias; Justyna Fert-Bober; elliot fishman; Elena Gallo; Marlies J E Kempers; HOWARD LEVY; Bart Loeys
Loss-of-function mutations in TGFB2 cause a syndromic presentation of thoracic aortic aneurysm.
Nature genetics 2012;44(8):922-7.
2012: Rebekah L Gundry; Ondrej Juhasz; Shannon Marshall; Samuel Milanovich; Fallon K Noto; Kimberly Raginski; Sridhar Rao; Daniel R Riordon; Hyun-Jin Tae; Yelena Tarasova; Irina Tchernyshyov; Jennifer E Van Eyk; Robert P Wersto; Olena Wiedemeier; Bernd Wollscheid; Damaris Bausch-Fluck; Subarna Bhattacharya; Sandra Chuppa; Stephen A Duncan; Kenneth R Boheler
A cell surfaceome map for immunophenotyping and sorting pluripotent stem cells.
Molecular & cellular proteomics : MCP 2012;11(8):303-16.
2012: Euan Ashley; Colleen Caleshu; Patrick T Ellinor; Joe G. N. Garcia; David M Herrington; Ray E Hershberger; Carolyn Y Ho; Julie A Johnson; Steven Kittner; Calum A MacRae; Gia Mudd-Martin; Daniel J Rader; Dan M Roden; Derek Scholes; Frank W Sellke; Jeffrey A Towbin; Jennifer E Van Eyk; Bradford B Worrall
Genetics and cardiovascular disease: a policy statement from the American Heart Association.
Circulation 2012;126(1):142-57.
2012: Mingyi Wang; Robert P Wersto; James Wu; Jing Zhang; Mingming Zhao; Zongming Fu; Liqun Jiang; Benjamin Khazan; Alexander W Krug; Robert Monticone; Maria Pikilidou; Richard Telljohann; Jennifer E Van Eyk; Edward G Lakatta
MFG-E8 activates proliferation of vascular smooth muscle cells via integrin signaling.
Aging cell 2012;11(3):500-8.
2012: Cathrine Husberg; Giulio Agnetti; Geir Christensen; Ronald J Holewinski; Jennifer E Van Eyk
Dephosphorylation of cardiac proteins in vitro - a matter of phosphatase specificity.
Proteomics 2012;12(7):973-8.
2012: Byung-Min Chung; Christopher I Murray; Jennifer E Van Eyk; Pierre A Coulombe
Identification of novel interaction between annexin A2 and keratin 17: evidence for reciprocal regulation.
The Journal of biological chemistry 2012;287(10):7573-81.
2012: Maggie P Y Lam; Arjen Scholten; Jennifer E Van Eyk; Fernando Vivanco; Henning Hermjakob; Peipei Ping
HUPO 2011: The new Cardiovascular Initiative - integrating proteomics and cardiovascular biology in health and disease.
Proteomics 2012;12(6):749-51.
2012: Miroslava Stastna; Jennifer E Van Eyk
Investigating the secretome: lessons about the cells that comprise the heart.
Circulation. Cardiovascular genetics 2012;5(1):o8-o18.
2012: Miroslava Stastna; Jennifer E Van Eyk
Secreted proteins as a fundamental source for biomarker discovery.
Proteomics 2012;12(4-5):722-35.
2012: Christopher I Murray; Robert N O'Meally; Helge Uhrigshardt; Robert N Cole; Jennifer E Van Eyk
Identification and quantification of S-nitrosylation by cysteine reactive tandem mass tag switch assay.
Molecular & cellular proteomics : MCP 2012;11(2):M111.013441.
2012: Konstantinos Malliaras; Giselle Galang; John Terrovitis; Ke Cheng; Florian Schoenhoff; Yiqiang Zhang; Tao-Sheng Li; Linda Marbán; Jennifer E Van Eyk; Tarun Chakravarty; Daniel Luthringer; Eduardo Marbán
Safety and efficacy of allogeneic cell therapy in infarcted rats transplanted with mismatched cardiosphere-derived cells.
Circulation 2012;125(1):100-12.
2012: Jon T Giles; Felipe Andrade; Joan M Bathon; Clifton O Bingham; Justyna Fert-Bober; Karen Fox-Talbot; Dimitrios Pappas; Jin Kyun Park; Antony Rosen; Jennifer E Van Eyk; Marc K Halushka
Myocardial citrullination in rheumatoid arthritis: a correlative histopathologic study.
Arthritis research & therapy 2012;14(1):R39.
2011: Xiaoou Pan; Jennifer E Van Eyk; Lesley A Kane; Pierre A Coulombe
Type I keratin 17 protein is phosphorylated on serine 44 by p90 ribosomal protein S6 kinase 1 (RSK1) in a growth- and stress-dependent fashion.
The Journal of biological chemistry 2011;286(49):42403-13.
2011: Brian O'Rourke; Jennifer E Van Eyk; Darren Foster
Mitochondrial protein phosphorylation as a regulatory modality: implications for mitochondrial dysfunction in heart failure.
Congestive heart failure (Greenwich, Conn.) 2011;17(6):269-82.
2011: Jennifer E Van Eyk
Maximizing the utility of proteomics: an educational series.
Circulation. Cardiovascular genetics 2011;4(5):574.
2011: Sheng-Bing Wang; Darren Foster; David A Kass; Brian O'Rourke; Jasma Rucker; Jennifer E Van Eyk
Redox regulation of mitochondrial ATP synthase: implications for cardiac resynchronization therapy.
Circulation research 2011;109(7):750-7.
2011: William J Savage; EMILY BARRON-CASELLA; Zongming Fu; Pratima Dulloor; Lisa Williams; Barbara J Crain; Desiree A White; Jacky Jennings; Jennifer E Van Eyk; Michael R DeBaun; Allen Everett; James F Casella
Plasma glial fibrillary acidic protein levels in children with sickle cell disease.
American journal of hematology 2011;86(5):427-9.
2011: Carlo G Tocchetti; Brian A Stanley; Christopher I Murray; Vidhya Sivakumaran; Sonia Donzelli; Daniele Mancardi; Pasquale Pagliaro; Wei Dong Gao; Jennifer E Van Eyk; David A Kass; David A Wink; Nazareno Paolocci
Playing with cardiac "redox switches": the "HNO way" to modulate cardiac function.
Antioxidants & redox signaling 2011;14(9):1687-98.
2011: Brian A Stanley; David Raymond Graham; Jeanne James; Megan Mitsak; Patrick M Tarwater; Jeff Robbins; Jennifer E Van Eyk
Altered myofilament stoichiometry in response to heart failure in a cardioprotective α-myosin heavy chain transgenic rabbit model.
Proteomics. Clinical applications 2011;5(3-4):147-58.
2011: Chunling Fan; Zongming Fu; QINGNING SU; Daniel Angelini; Jennifer E Van Eyk; Roger Johns
S100A11 mediates hypoxia-induced mitogenic factor (HIMF)-induced smooth muscle cell migration, vesicular exocytosis, and nuclear activation.
Molecular & cellular proteomics : MCP 2011;10(3):M110.000901.
2011: Christopher I Murray; Lesley A Kane; Helge Uhrigshardt; Sheng-Bing Wang; Jennifer E Van Eyk
Site-mapping of in vitro S-nitrosation in cardiac mitochondria: implications for cardioprotection.
Molecular & cellular proteomics : MCP 2011;10(3):M110.004721.
2011: Giulio Agnetti; Cathrine Husberg; Jennifer E Van Eyk
Divide and conquer: the application of organelle proteomics to heart failure.
Circulation research 2011;108(4):512-26.
2011: Jennifer E Van Eyk
Overview: the maturing of proteomics in cardiovascular research.
Circulation research 2011;108(4):490-8.
2011: Melanie Y White; David A Brown; Simon Sheng; Robert N Cole; Brian O'Rourke; Jennifer E Van Eyk
Parallel proteomics to improve coverage and confidence in the partially annotated Oryctolagus cuniculus mitochondrial proteome.
Molecular & cellular proteomics : MCP 2011;10(2):M110.004291.
2011: Lei Zheng; Kelly Foley; LANQING HUANG; Ashley Leubner; Guanglan Mo; Kelly Olino; BARISH EDIL; Masamichi Mizuma; Rajni Sharma; DUNG LE; Robert A Anders; PETER ILLEI; Jennifer E Van Eyk; Anirban Maitra; Daniel Laheru; Elizabeth M Jaffee
Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.
PloS one 2011;6(4):e19390.
2011: Anthony Cammarato; Christian H Ahrens; Nakissa N Alayari; Ermir Qeli; Jasma Rucker; Mary C Reedy; Christian M Zmasek; Marjan Gucek; Robert N Cole; Jennifer E Van Eyk; Rolf Bodmer; Brian O'Rourke; Sanford I Bernstein; Darren Foster
A mighty small heart: the cardiac proteome of adult Drosophila melanogaster.
PloS one 2011;6(4):e18497.
2011: Simon Sheng; Helena Skalnikova; Andrew Meng; John Tra; Qin Fu; Allen Everett; Jennifer E Van Eyk
Intact protein separation by one- and two-dimensional liquid chromatography for the comparative proteomic separation of partitioned serum or plasma.
Methods in molecular biology (Clifton, N.J.) 2011;728():29-46.
2011: Miroslava Stastna; Ashley Behrens; Peter J McDonnell; Jennifer E Van Eyk
Analysis of protein composition of rabbit aqueous humor following two different cataract surgery incision procedures using 2-DE and LC-MS/MS.
Proteome science 2011;9(1):8.
2010: Kenneth A Ellenbogen; Michael R Gold; Timothy E Meyer; Ignacio Fernndez Lozano; Suneet Mittal; Alan D Waggoner; Bernd Lemke; Jagmeet P Singh; Francis G Spinale; Jennifer E Van Eyk; Jeffrey Whitehill; Stanislav Weiner; Maninder Bedi; Joshua Rapkin; Kenneth M Stein
Primary results from the SmartDelay determined AV optimization: a comparison to other AV delay methods used in cardiac resynchronization therapy (SMART-AV) trial: a randomized trial comparing empirical, echocardiography-guided, and algorithmic atrioventricular delay programming in cardiac resynchronization therapy.
Circulation 2010;122(25):2660-8.
2010: Lisa M Williams; Zongming Fu; Pratima Dulloor; Timothy Yen; EMILY BARRON-CASELLA; William J Savage; Jennifer E Van Eyk; James F Casella; Allen Everett
Hemoglobin depletion from plasma: considerations for proteomic discovery in sickle cell disease and other hemolytic processes.
Proteomics. Clinical applications 2010;4(12):926-30.
2010: Scott D Patterson; Jennifer E Van Eyk; Rosamonde E Banks
Report from the Wellcome Trust/EBA “Perspectives in Clinical Proteomics” retreat--a strategy to implement next-generation proteomic analyses to the clinic for patient benefit: pathway to translation.
Proteomics. Clinical applications 2010;4(12):883-7.
2010: Steven M Dudek; Eddie T Chiang; Sara M Camp; Yurong Guo; Jing Zhao; Mary E Brown; Patrick A Singleton; Lichun Wang; Anjali Desai; Fernando T Arce; Ratnesh Lal; Jennifer E Van Eyk; Syed Z Imam; Joe G. N. Garcia
Abl tyrosine kinase phosphorylates nonmuscle Myosin light chain kinase to regulate endothelial barrier function.
Molecular biology of the cell 2010;21(22):4042-56.
2010: Yixin Lin; Qin Fu; Jie Zhu; Julie M Miller; Jennifer E Van Eyk
Development of a qualitative sequential immunoassay for characterizing the intrinsic properties of circulating cardiac troponin I.
Clinical chemistry 2010;56(8):1307-19.
2010: Rebekah L Gundry; Irina Tchernyshyov; Shijun Sheng; Yelena Tarasova; Kimberly Raginski; Kenneth R Boheler; Jennifer E Van Eyk
Expanding the mouse embryonic stem cell proteome: combining three proteomic approaches.
Proteomics 2010;10(14):2728-32.
2010: Geoffrey G Hesketh; Manish Shah; Victoria L Halperin; CA Cooke; Fadi G Akar; Timothy E Yen; David A Kass; Carolyn E Machamer; Jennifer E Van Eyk; Gordon F Tomaselli
Ultrastructure and regulation of lateralized connexin43 in the failing heart.
Circulation research 2010;106(6):1153-63.
2010: Peter Matt; David L Huso; JENNIFER HABASHI; Tammy Holm; Jeff Doyle; Florian Schoenhoff; Guosheng Liu; James H Black; Jennifer E Van Eyk; Harry C Dietz
Murine model of surgically induced acute aortic dissection type A.
The Journal of thoracic and cardiovascular surgery 2010;139(4):1041-7.
2010: Kim A Eagle; Geoffrey S Ginsburg; Kiran Musunuru; William C Aird; Robert S Balaban; Susan K Bennett; Roger S Blumenthal; Shaun R Coughlin; Karina W Davidson; Edward D Frohlich; Philip Greenland; Gail P Jarvik; Peter Libby; Carl J Pepine; Jeremy N Ruskin; Arthur E Stillman; Jennifer E Van Eyk; H Eser Tolunay; Cheryl L McDonald; Sidney C Smith
Identifying patients at high risk of a cardiovascular event in the near future: current status and future directions: report of a national heart, lung, and blood institute working group.
Circulation 2010;121(12):1447-54.
2010: Agnieszka Galińska; Victoria Hatch; Roger Craig; Anne M Murphy; Jennifer E Van Eyk; C-L Albert Wang; William Lehman; Darren Foster
The C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filaments.
Circulation research 2010;106(4):705-11.
2010: Qin Fu; Florian S Schoenhoff; William J Savage; Pingbo Zhang; Jennifer E Van Eyk
Multiplex assays for biomarker research and clinical application: translational science coming of age.
Proteomics. Clinical applications 2010;4(3):271-84.
2010: Lesley A Kane; Matthew J Youngman; Robert E Jensen; Jennifer E Van Eyk
Phosphorylation of the F(1)F(o) ATP synthase beta subunit: functional and structural consequences assessed in a model system.
Circulation research 2010;106(3):504-13.
2010: Patrick T Ellinor; Jennifer E Van Eyk
Top advances in functional genomics and translational biology for 2009.
Circulation. Cardiovascular genetics 2010;3(1):106-8.
2010: Giulio Agnetti; Nina Kaludercic; Lesley A Kane; Steven T Elliott; Yurong Guo; Khalid Chakir; Daya Samantapudi; Nazareno Paolocci; Gordon F Tomaselli; David A Kass; Jennifer E Van Eyk
Modulation of mitochondrial proteome and improved mitochondrial function by biventricular pacing of dyssynchronous failing hearts.
Circulation. Cardiovascular genetics 2010;3(1):78-87.
2010: Qin Fu; Jie Zhu; Jennifer E Van Eyk
Comparison of multiplex immunoassay platforms.
Clinical chemistry 2010;56(2):314-8.
2010: Anna Köttgen; Shih-Jen Hwang; Martin G Larson; Jennifer E Van Eyk; Qin Fu; Emelia Benjamin; Abbas Dehghan; Nicole L Glazer; WEN KAO; Tamara B Harris; Vilmundur Gudnason; Michael G Shlipak; Qiong Yang; Josef Coresh; Daniel Levy; Caroline S Fox
Uromodulin levels associate with a common UMOD variant and risk for incident CKD.
Journal of the American Society of Nephrology : JASN 2010;21(2):337-44.
2010: Praveen Balabaskaran Nina; Natalya V Dudkina; Lesley A Kane; Jennifer E Van Eyk; Egbert J Boekema; Michael W Mather; Akhil B Vaidya
Highly divergent mitochondrial ATP synthase complexes in Tetrahymena thermophila.
PLoS biology 2010;8(7):e1000418.
2010: Miroslava Stastna; Isotta Chimenti; Eduardo Marban; Jennifer E Van Eyk
Identification and functionality of proteomes secreted by rat cardiac stem cells and neonatal cardiomyocytes.
Proteomics 2010;10(2):245-53.
2010: Kenneth M Stein; Kenneth A Ellenbogen; Michael R Gold; Bernd Lemke; Ignacio Fernández Lozano; Suneet Mittal; Francis G Spinale; Jennifer E Van Eyk; Alan D Waggoner; Timothy E Meyer
SmartDelay determined AV optimization: a comparison of AV delay methods used in cardiac resynchronization therapy (SMART-AV): rationale and design.
Pacing and clinical electrophysiology : PACE 2010;33(1):54-63.
2009: Rebekah L Gundry; Kimberly Raginski; Yelena Tarasova; Irina Tchernyshyov; Damaris Bausch-Fluck; Steven T Elliott; Kenneth R Boheler; Jennifer E Van Eyk; Bernd Wollscheid
The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation.
Molecular & cellular proteomics : MCP 2009;8(11):2555-69.
2009: Rebekah L Gundry; Melanie Y White; Christopher I Murray; Lesley A Kane; Qin Fu; Brian A Stanley; Jennifer E Van Eyk
Preparation of proteins and peptides for mass spectrometry analysis in a bottom-up proteomics workflow.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2009;Chapter 10():Unit10.25.
2009: Geoffrey G Hesketh; Jennifer E Van Eyk; Gordon F Tomaselli
Mechanisms of gap junction traffic in health and disease.
Journal of cardiovascular pharmacology 2009;54(4):263-72.
2009: Kate Hsu; Naiwen Chi; Marjan Gucek; Jennifer E Van Eyk; Robert N Cole; Marie Lin; Darren Foster
Miltenberger blood group antigen type III (Mi.III) enhances the expression of band 3.
Blood 2009;114(9):1919-28.
2009: Peter Matt; Florian Schoenhoff; JENNIFER HABASHI; Tammy Holm; Christel Van Erp; David Loch; Olga D Carlson; Benjamin F Griswold; Qin Fu; Julie De Backer; Bart Loeys; David L Huso; Nazli B McDonnell; Jennifer E Van Eyk; Harry C Dietz
Circulating transforming growth factor-beta in Marfan syndrome.
Circulation 2009;120(6):526-32.
2009: Christopher I Murray; Meagan Barrett; Jennifer E Van Eyk
Assessment of ProteoExtract subcellular fractionation kit reveals limited and incomplete enrichment of nuclear subproteome from frozen liver and heart tissue.
Proteomics 2009;9(15):3934-8.
2009: Zongming Fu; Mingyi Wang; Marjan Gucek; Jing Zhang; James Wu; Liqun Jiang; Robert Monticone; Benjamin Khazan; Richard Telljohann; Julie Mattison; Simon Sheng; Robert N Cole; Gaia Spinetti; Gianfranco Pintus; Lijuan Liu; Frank D Kolodgie; Renu Virmani; Harold A Spurgeon; Donald Ingram; Allen Everett; Edward G Lakatta; Jennifer E Van Eyk
Milk fat globule protein epidermal growth factor-8: a pivotal relay element within the angiotensin II and monocyte chemoattractant protein-1 signaling cascade mediating vascular smooth muscle cells invasion.
Circulation research 2009;104(12):1337-46.
2009: Miroslava Stastna; ROSELLE ABRAHAM; Jennifer E Van Eyk
Cardiac stem/progenitor cells, secreted proteins, and proteomics.
FEBS letters 2009;583(11):1800-7.
2009: Ping Gao; Irina Tchernyshyov; Tsung-Cheng Chang; Yun-Sil Lee; Kayoko Kita; Takafumi Ochi; Karen I Zeller; Angelo M DeMarzo; Jennifer E Van Eyk; Joshua T Mendell; Chi Dang
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism.
Nature 2009;458(7239):762-5.
2009: Darren Foster; Jennifer E Van Eyk; Eduardo Marban; Brian O'Rourke
Redox signaling and protein phosphorylation in mitochondria: progress and prospects.
Journal of bioenergetics and biomembranes 2009;41(2):159-68.
2009: Lesley A Kane; Jennifer E Van Eyk
Post-translational modifications of ATP synthase in the heart: biology and function.
Journal of bioenergetics and biomembranes 2009;41(2):145-50.
2009: Rebekah L Gundry; Melanie Y White; Julie Nogee; Irina Tchernyshyov; Jennifer E Van Eyk
Assessment of albumin removal from an immunoaffinity spin column: critical implications for proteomic examination of the albuminome and albumin-depleted samples.
Proteomics 2009;9(7):2021-8.
2009: Florian S Schoenhoff; Qin Fu; Jennifer E Van Eyk
Cardiovascular proteomics: implications for clinical applications.
Clinics in laboratory medicine 2009;29(1):87-99.
2008: David Raymond Graham; Megan J Mitsak; Steven T Elliott; Dawn Chen; Stephen A Whelan; Gerald W Hart; Jennifer E Van Eyk
Two-dimensional gel-based approaches for the assessment of N-Linked and O-GlcNAc glycosylation in human and simian immunodeficiency viruses.
Proteomics 2008;8(23-24):4919-30.
2008: Darren Foster; Brian O'Rourke; Jennifer E Van Eyk
What can mitochondrial proteomics tell us about cardioprotection afforded by preconditioning?
Expert review of proteomics 2008;5(5):633-6.
2008: Gail D Pearson; Richard Devereux; Bart Loeys; Cheryl L Maslen; Dianna Milewicz; Reed Pyeritz; Francesco Ramirez; Daniel Rifkin; Lynn Sakai; Lars Svensson; Andy Wessels; Jennifer E Van Eyk; Harry C Dietz
Report of the National Heart, Lung, and Blood Institute and National Marfan Foundation Working Group on research in Marfan syndrome and related disorders.
Circulation 2008;118(7):785-91.
2008: Giulio Agnetti; Karel Bezstarosti; Dick H W Dekkers; Adrie J M Verhoeven; Emanuele Giordano; Carlo Guarnieri; Claudio Marcello Caldarera; Jennifer E Van Eyk; Jos M J Lamers
Proteomic profiling of endothelin-1-stimulated hypertrophic cardiomyocytes reveals the increase of four different desmin species and alpha-B-crystallin.
Biochimica et biophysica acta 2008;1784(7-8):1068-76.
2008: Melanie Y White; Alistair V G Edwards; Stuart J Cordwell; Jennifer E Van Eyk
Mitochondria: A mirror into cellular dysfunction in heart disease.
Proteomics. Clinical applications 2008;2(6):845-61.
2008: Manuel Mayr; Jennifer E Van Eyk
Cardiovascular proteomics.
Proteomics. Clinical applications 2008;2(6):785-6.
2008: Ravi Tharakan; Lennart Martens; Jennifer E Van Eyk; David Raymond Graham
OMSSAGUI: An open-source user interface component to configure and run the OMSSA search engine.
Proteomics 2008;8(12):2376-8.
2008: Antoine Younes; Alexey E Lyashkov; David Raymond Graham; Anna Sheydina; Maria V Volkova; Megan Mitsak; Tatiana M Vinogradova; Yevgeniya O Lukyanenko; Yue Li; Abdul M Ruknudin; Kenneth R Boheler; Jennifer E Van Eyk; Edward G Lakatta
Ca(2+) -stimulated basal adenylyl cyclase activity localization in membrane lipid microdomains of cardiac sinoatrial nodal pacemaker cells.
The Journal of biological chemistry 2008;283(21):14461-8.
2008: Peter Matt; Zongming Fu; Qin Fu; Jennifer E Van Eyk
Biomarker discovery: proteome fractionation and separation in biological samples.
Physiological genomics 2008;33(1):12-7.
2008: Sarah Warburton; Melanie Y White; Jennifer E Van Eyk; Robert J Cotter; Peipei Ping; Michael J Dunn; Thomas M Vondriska
Cardiovascular Initiative of the Human Proteome Organisation, 5th Workshop October 2007, Seoul, Korea.
Proteomics 2008;8(5):924-6.
2008: M Suresh; Mukhtar Ahmed; Natalie G Ahn; Hainard Alexandre; Ramars Amanchy; Philip C Andrews; Joel S Bader; Brian M Balgley; Marcus Bantscheff; Keiryn Bennett; Erik Björling; Blagoy Blagoev; Ron Bose; Samir K Brahmachari; Alma S Burlingame; Xosé R Bustelo; Gerard Cagney; Greg T Cantin; Helene L Cardasis; Julio E Celis; Raghothama Chaerkady; Feixia Chu; Philip A Cole; Catherine E Costello; Robert J Cotter; David Crockett; James P DeLany; Angelo M DeMarzo; Leroi V DeSouza; Eric W Deutsch; Eric Dransfield; Gerard Drewes; Arnaud Droit; Michael J Dunn; Kojo Seys John Elenitoba-Johnson; Rob M Ewing; Jennifer E Van Eyk; Vitor Faca; Jayson Falkner; Xiangming Fang; Catherine Fenselau; Daniel Figeys; Pierre Gagné; Cecilia Gelfi; Kris Gevaert; Jeffrey M Gimble; Florian Gnad; renu goel; Pavel Gromov; Samir M Hanash; William S Hancock; H C Harsha; Gerald W Hart; Faith Hays; Fuchu He; Prashantha Hebbar; Kenny Helsens; Heiko Hermeking; Winston Hide; Karin Hjernø; Denis F Hochstrasser; Oliver Hofmann; David M Horn; Ralph Hruban; Nieves Ibarrola; Peter James; Ole N Jensen; Pia Hønnerup Jensen; Peter Jung; Richard Kumaran Kandasamy; Indu Kheterpal; Reiko F Kikuno; Ulrike Korf; Roman Körner; Bernhard Kuster; Min-Seok Kwon; Hyoung-Joo Lee; Young-Jin Lee; Michael Lefevre; Minna Lehvaslaiho; Pierre Lescuyer; Fredrik Levander; Megan S Lim; Christian Löbke; Joseph A Loo; Matthias Mann; Lennart Martens; Juan Martinez-Heredia; Mark McComb; James McRedmond; Alexander Mehrle; Rajasree Menon; Christine A Miller; Harald Mischak; S Sujatha Mohan; Riaz Mohmood; Henrik Molina; Michael F Moran; James D Morgan; Robert Moritz; Martine Morzel; David C Muddiman; Anuradha Nalli; J Daniel Navarro; Thomas A Neubert; Osamu Ohara; Rafael Oliva; Gilbert S Omenn; Masaaki Oyama; Young-Ki Paik; Kyla Pennington; Rainer Pepperkok; Balamurugan Periaswamy; Emanuel F Petricoin; Guy G Poirier; T S Keshava Prasad; Samuel O Purvine; B Abdul Rahiman; Prasanna Ramachandran; Y L Ramachandra; Robert H Rice; Jens Rick; Ragna H Ronnholm; Johanna Salonen; jean-charles sanchez; Thierry Sayd; Beerelli Seshi; Kripa Shankari; Shi Jun Sheng; Vivekananda Shetty; K Shivakumar; Richard J Simpson; Ravi Sirdeshmukh; K W Michael Siu; Jeffrey Smith; Richard D Smith; David J States; Sumio Sugano; Matthew Sullivan; Giulio Superti-Furga; Maarit Takatalo; Visith Thongboonkerd; Jonathan C Trinidad; Mathias Uhlen; Joël Vandekerckhove; Julian Vasilescu; Timothy D Veenstra; José-Manuel Vidal-Taboada; Mauno Vihinen; Robin Wait; Xiaoyue Wang; Stefan Wiemann; Billy Wu; Tao Xu; John R Yates; Jun Zhong; Ming Zhou; Yunping Zhu; Petra Zurbig; Akhilesh Pandey
Human Proteinpedia enables sharing of human protein data.
Nature biotechnology 2008;26(2):164-7.
2008: Peter Matt; JENNIFER HABASHI; Thierry Carrel; Duke E Cameron; Jennifer E Van Eyk; Harry C Dietz
Recent advances in understanding Marfan syndrome: should we now treat surgical patients with losartan?
The Journal of thoracic and cardiovascular surgery 2008;135(2):389-94.
2008: Carolyn M Feltes; Jennifer E Van Eyk; Hamid Rabb
Distant-organ changes after acute kidney injury.
Nephron. Physiology 2008;109(4):p80-4.
2008: Kirill V Tarasov; Yelena S Tarasova; Wai Leong Tam; Daniel R Riordon; Steven T Elliott; Gabriela Kania; Jinliang Li; Satoshi Yamanaka; David G Crider; Gianluca Testa; Ronald A Li; Bing Lim; Colin L Stewart; Yie Liu; Jennifer E Van Eyk; Robert P Wersto; Anna M Wobus; Kenneth R Boheler
B-MYB is essential for normal cell cycle progression and chromosomal stability of embryonic stem cells.
PloS one 2008;3(6):e2478.
2008: Satoshi Yamanaka; Jinliang Li; Gabriela Kania; Steve Elliott; Robert P Wersto; Jennifer E Van Eyk; Anna M Wobus; Kenneth R Boheler
Pluripotency of embryonic stem cells.
Cell and tissue research 2008;331(1):5-22.
2007: Miroslava Stastna; Ashley Behrens; Guillermo Noguera; Samantha Herretes; Peter J McDonnell; Jennifer E Van Eyk
Proteomics of the aqueous humor in healthy New Zealand rabbits.
Proteomics 2007;7(23):4358-75.
2007: Peter Matt; Zongming Fu; Thierry Carrel; David L Huso; Stefan Dirnhofer; Ivan Lefkovits; Hans Zerkowski; Jennifer E Van Eyk
Proteomic alterations in heat shock protein 27 and identification of phosphoproteins in ascending aortic aneurysm associated with bicuspid and tricuspid aortic valve.
Journal of molecular and cellular cardiology 2007;43(6):792-801.
2007: Rebekah L Gundry; Jennifer E Van Eyk
Unraveling the complexity of circulating forms of brain natriuretic peptide.
Clinical chemistry 2007;53(7):1181-2.
2007: Giulio Agnetti; Lesley A Kane; Carlo Guarnieri; Claudio Marcello Caldarera; Jennifer E Van Eyk
Proteomic technologies in the study of kinases: novel tools for the investigation of PKC in the heart.
Pharmacological research : the official journal of the Italian Pharmacological Society 2007;55(6):511-22.
2007: Yurong Guo; Patrick A Singleton; Austin Rowshan; Marjan Gucek; Robert N Cole; David Raymond Graham; Jennifer E Van Eyk; Joe G. N. Garcia
Quantitative proteomics analysis of human endothelial cell membrane rafts: evidence of MARCKS and MRP regulation in the sphingosine 1-phosphate-induced barrier enhancement.
Molecular & cellular proteomics : MCP 2007;6(4):689-96.
2007: Mischak Harald; Rolf Apweiler; Rosamonde E Banks; Mark Conaway; Joshua Coon; Anna Dominiczak; Jochen H H Ehrich; Danilo Fliser; Mark Girolami; Henning Hermjakob; Denis Hochstrasser; Joachim Jankowski; Bruce A Julian; Walter Kolch; Ziad A Massy; Christian Neusuess; Jan Novak; Karlheinz Peter; Kasper Rossing; Joost Schanstra; O John Semmes; Dan Theodorescu; Visith Thongboonkerd; Eva M Weissinger; Jennifer E Van Eyk; Tadashi Yamamoto
Clinical proteomics: A need to define the field and to begin to set adequate standards.
Proteomics. Clinical applications 2007;1(2):148-56.
2007: Santhi Ganesh; Yugal Sharma; Judith Dayhoff; Henry M Fales; Jennifer E Van Eyk; Thomas S Kickler; Eric M Billings; Elizabeth G Nabel
Detection of venous thromboembolism by proteomic serum biomarkers.
PloS one 2007;2(6):e544.
2007: Melanie Y White; Jennifer E Van Eyk
Cardiovascular proteomics: past, present, and future.
Molecular diagnosis & therapy 2007;11(2):83-95.
2007: Yurong Guo; Zongming Fu; Jennifer E Van Eyk
A proteomic primer for the clinician.
Proceedings of the American Thoracic Society 2007;4(1):9-17.
2007: Peter Matt; Thierry Carrel; Melanie White; Ivan Lefkovits; Jennifer E Van Eyk
Proteomics in cardiovascular surgery.
The Journal of thoracic and cardiovascular surgery 2007;133(1):210-4.
2007: Qin Fu; Diane E Bovenkamp; Jennifer E Van Eyk
A rapid, economical, and reproducible method for human serum delipidation and albumin and IgG removal for proteomic analysis.
Methods in molecular biology (Clifton, N.J.) 2007;357():365-71.
2007: Diane E Bovenkamp; Brian A Stanley; Jennifer E Van Eyk
Optimization of cardiac troponin I pull-down by IDM affinity beads and SELDI.
Methods in molecular biology (Clifton, N.J.) 2007;357():91-102.
2007: Lesley A Kane; Irina Neverova; Jennifer E Van Eyk
Subfractionation of heart tissue: the "in sequence" myofilament protein extraction of myocardial tissue.
Methods in molecular biology (Clifton, N.J.) 2007;357():87-90.
2007: Brian A Stanley; Jennifer E Van Eyk
A method for the effective depletion of albumin from cellular extracts: application to human myocardium.
Methods in molecular biology (Clifton, N.J.) 2007;357():67-70.
2007: Brian A Stanley; Jennifer E Van Eyk
A solubility optimization protocol for two-dimensional gel electrophoresis of cardiac tissue.
Methods in molecular biology (Clifton, N.J.) 2007;357():59-65.
2006: Todd McDonald; Simon Sheng; Brian Stanley; Dawn Chen; Young Ko; Robert N Cole; Peter L Pedersen; Jennifer E Van Eyk
Expanding the subproteome of the inner mitochondria using protein separation technologies: one- and two-dimensional liquid chromatography and two-dimensional gel electrophoresis.
Molecular & cellular proteomics : MCP 2006;5(12):2392-411.
2006: Lene H Madsen; Geir Christensen; Terje Lund; Victor L Serebruany; Chris B Granger; Ingvild Hoen; Zanina Grieg; John H Alexander; Allan S Jaffe; Jennifer E Van Eyk; Dan Atar
Time course of degradation of cardiac troponin I in patients with acute ST-elevation myocardial infarction: the ASSENT-2 troponin substudy.
Circulation research 2006;99(10):1141-7.
2006: Sara Arab; Anthony O Gramolini; Peipei Ping; Thomas Kislinger; Brian Stanley; Jennifer E Van Eyk; Maral Ouzounian; David H MacLennan; Andrew Emili; Peter P Liu
Cardiovascular proteomics: tools to develop novel biomarkers and potential applications.
Journal of the American College of Cardiology 2006;48(9):1733-41.
2006: Lesley A Kane; Christina K Yung; Giulio Agnetti; Irina Neverova; Jennifer E Van Eyk
Optimization of paper bridge loading for 2-DE analysis in the basic pH region: application to the mitochondrial subproteome.
Proteomics 2006;6(21):5683-7.
2006: Chunguang G Yang; Stephen J Granite; Jennifer E Van Eyk; Raimond L Winslow
MASCOT HTML and XML parser: an implementation of a novel object model for protein identification data.
Proteomics 2006;6(21):5688-93.
2006: Nadiya A Narolska; Nicoletta Piroddi; Alexandra Belus; Nicky M Boontje; Beatrice Scellini; Sascha Deppermann; Ruud Zaremba; René J P Musters; Cris dos Remedios; Kornelia Jaquet; Darren Foster; Anne M Murphy; Jennifer E Van Eyk; Chiara Tesi; Corrado Poggesi; Jolanda van der Velden; Ger J M Stienen
Impaired diastolic function after exchange of endogenous troponin I with C-terminal truncated troponin I in human cardiac muscle.
Circulation research 2006;99(9):1012-20.
2006: D. Kent Arrell; Steven T Elliott; Lesley A Kane; Yurong Guo; Young H Ko; Peter L Pedersen; John Robinson; Mitsushige Murata; Anne M Murphy; Eduardo Marban; Jennifer E Van Eyk
Proteomic analysis of pharmacological preconditioning: novel protein targets converge to mitochondrial metabolism pathways.
Circulation research 2006;99(7):706-14.
2006: Qin Fu; Jennifer E Van Eyk
Proteomics and heart disease: identifying biomarkers of clinical utility.
Expert review of proteomics 2006;3(2):237-49.
2006: J Gordon Boyd; Ali Jahed; Todd G McDonald; Karmen M Krol; Jennifer E Van Eyk; Ronald Doucette; Michael D Kawaja
Proteomic evaluation reveals that olfactory ensheathing cells but not Schwann cells express calponin.
Glia 2006;53(4):434-40.
2006: Yanbin Ji; Irina Neverova; Jennifer E Van Eyk; Brian M Bennett
Nitration of tyrosine 92 mediates the activation of rat microsomal glutathione s-transferase by peroxynitrite.
The Journal of biological chemistry 2006;281(4):1986-91.
2006: Marc R Wilkins; Ron D Appel; Jennifer E Van Eyk; Maxey C M Chung; Angelika Görg; Michael Hecker; Lukas A Huber; Hanno Langen; Andrew J Link; Young-Ki Paik; Scott D Patterson; Stephen R Pennington; Thierry Rabilloud; Richard J Simpson; Walter Weiss; Michael J Dunn
Guidelines for the next 10 years of proteomics.
Proteomics 2006;6(1):4-8.
2006: Simon Sheng; Dawn Chen; Jennifer E Van Eyk
Multidimensional liquid chromatography separation of intact proteins by chromatographic focusing and reversed phase of the human serum proteome: optimization and protein database.
Molecular & cellular proteomics : MCP 2006;5(1):26-34.
2005: Nina Buscemi; Chris Murray; Amanda Doherty-Kirby; Gilles Lajoie; Mark A Sussman; Jennifer E Van Eyk
Myocardial subproteomic analysis of a constitutively active Rac1-expressing transgenic mouse with lethal myocardial hypertrophy.
American journal of physiology. Heart and circulatory physiology 2005;289(6):H2325-33.
2005: Yurong Guo; Shwu-Fan Ma; Dmitry N Grigoryev; Jennifer E Van Eyk; Joe G. N. Garcia
1-DE MS and 2-D LC-MS analysis of the mouse bronchoalveolar lavage proteome.
Proteomics 2005;5(17):4608-24.
2005: David A Colantonio; Christy Dunkinson; Diane E Bovenkamp; Jennifer E Van Eyk
Effective removal of albumin from serum.
Proteomics 2005;5(15):3831-5.
2005: Qin Fu; Christopher P Garnham; Steven T Elliott; Diane E Bovenkamp; Jennifer E Van Eyk
A robust, streamlined, and reproducible method for proteomic analysis of serum by delipidation, albumin and IgG depletion, and two-dimensional gel electrophoresis.
Proteomics 2005;5(10):2656-64.
2005: David Raymond Graham; Christopher P Garnham; Qin Fu; Jeffrey Robbins; Jennifer E Van Eyk
Improvements in two-dimensional gel electrophoresis by utilizing a low cost "in-house" neutral pH sodium dodecyl sulfate-polyacrylamide gel electrophoresis system.
Proteomics 2005;5(9):2309-14.
2005: Jeremy A Simpson; Ralf Labugger; Christine P Collier; Robert J Brison; Steve Iscoe; Jennifer E Van Eyk
Fast and slow skeletal troponin I in serum from patients with various skeletal muscle disorders: a pilot study.
Clinical chemistry 2005;51(6):966-72.
2005: David Raymond Graham; Steven T Elliott; Jennifer E Van Eyk
Broad-based proteomic strategies: a practical guide to proteomics and functional screening.
The Journal of physiology 2005;563(Pt 1):1-9.
2005: Irina Neverova; Jennifer E Van Eyk
Role of chromatographic techniques in proteomic analysis.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;815(1-2):51-63.
2004: Steven T Elliott; David G Crider; Christopher P Garnham; Christopher P Garham; Kenneth R Boheler; Jennifer E Van Eyk
Two-dimensional gel electrophoresis database of murine R1 embryonic stem cells.
Proteomics 2004;4(12):3813-32.
2004: Jason L McDonough; Jennifer E Van Eyk
Developing the next generation of cardiac markers: disease-induced modifications of troponin I.
Progress in cardiovascular diseases 2004;47(3):207-16.
2004: David A Colantonio; Jennifer E Van Eyk; Karin Przyklenk
Stunned peri-infarct canine myocardium is characterized by degradation of troponin T, not troponin I.
Cardiovascular research 2004;63(2):217-25.
2004: Christopher B Granger; Jennifer E Van Eyk; Stephen Mockrin; N Leigh Anderson
National Heart, Lung, And Blood Institute Clinical Proteomics Working Group report.
Circulation 2004;109(14):1697-703.
2004: Marcella Canton; Irina Neverova; Roberta Menabò; Jennifer E Van Eyk; Fabio Di Lisa
Evidence of myofibrillar protein oxidation induced by postischemic reperfusion in isolated rat hearts.
American journal of physiology. Heart and circulatory physiology 2004;286(3):H870-7.
2004: Jennifer E Van Eyk
Lessons from old and new kinases.
Circulation research 2004;94(2):135-7.
2004: Jeremy A Simpson; Jennifer E Van Eyk; Steve Iscoe
Respiratory muscle injury, fatigue and serum skeletal troponin I in rat.
The Journal of physiology 2004;554(Pt 3):891-903.
2004: Brian A Stanley; Rebekah L Gundry; Robert J Cotter; Jennifer E Van Eyk
Heart disease, clinical proteomics and mass spectrometry.
Disease markers 2004;20(3):167-78.
2003: Monica X Li; Xu Wang; Darrin A Lindhout; Nina Buscemi; Jennifer E Van Eyk; Brian D Sykes
Phosphorylation and mutation of human cardiac troponin I deferentially destabilize the interaction of the functional regions of troponin I with troponin C.
Biochemistry 2003;42(49):14460-8.
2003: Darren Foster; Teruo Noguchi; Peter VanBuren; Anne M Murphy; Jennifer E Van Eyk
C-terminal truncation of cardiac troponin I causes divergent effects on ATPase and force: implications for the pathophysiology of myocardial stunning.
Circulation research 2003;93(10):917-24.
2003: Nina Buscemi; Amanda Doherty-Kirby; Mark A Sussman; Gilles Lajoie; Jennifer E Van Eyk
Proteomic analysis of Rac1 transgenic mice displaying dilated cardiomyopathy reveals an increase in creatine kinase M-chain protein abundance.
Molecular and cellular biochemistry 2003;251(1-2):145-51.
2003: Todd G McDonald; Jennifer E Van Eyk
Mitochondrial proteomics. Undercover in the lipid bilayer.
Basic research in cardiology 2003;98(4):219-27.
2003: Brian A Stanley; Irina Neverova; Heather A Brown; Jennifer E Van Eyk
Optimizing protein solubility for two-dimensional gel electrophoresis analysis of human myocardium.
Proteomics 2003;3(6):815-20.
2003: Ralf Labugger; Jeremy A Simpson; Michelle Quick; Heather A Brown; Christine E Collier; Irina Neverova; Jennifer E Van Eyk
Strategy for analysis of cardiac troponins in biological samples with a combination of affinity chromatography and mass spectrometry.
Clinical chemistry 2003;49(6 Pt 1):873-9.
2003: PK McFawn; L Shen; Sandra G Vincent; A Mak; Jennifer E Van Eyk; John T Fisher
Calcium-independent contraction and sensitization of airway smooth muscle by p21-activated protein kinase.
American journal of physiology. Lung cellular and molecular physiology 2003;284(5):L863-70.
2003: Dan Atar; Lene H Madsen; Ralf Labugger; Jennifer E Van Eyk
[Molecular modifications of troponin I and T detected in serum from patients with acute myocardial infarction].
Ugeskrift for laeger 2003;165(2):116-20.
2003: Cristobal G dos Remedios; C C Liew; P D Allen; Raimond L Winslow; Jennifer E Van Eyk; M J Dunn
Genomics, proteomics and bioinformatics of human heart failure.
Journal of muscle research and cell motility 2003;24(4-6):251-60.
2002: Wenhong Xu; Yongge Liu; Sheng Wang; Todd McDonald; Jennifer E Van Eyk; Agnieszka Sidor; Brian O'Rourke
Cytoprotective role of Ca2+- activated K+ channels in the cardiac inner mitochondrial membrane.
Science (New York, N.Y.) 2002;298(5595):1029-33.
2002: Nina Buscemi; Darren Foster; Irina Neverova; Jennifer E Van Eyk
p21-activated kinase increases the calcium sensitivity of rat triton-skinned cardiac muscle fiber bundles via a mechanism potentially involving novel phosphorylation of troponin I.
Circulation research 2002;91(6):509-16.
2002: Jason L McDonough; Irina Neverova; Jennifer E Van Eyk
Proteomic analysis of human biopsy samples by single two-dimensional electrophoresis: Coomassie, silver, mass spectrometry, and Western blotting.
Proteomics 2002;2(8):978-87.
2002: Jeremy A Simpson; Ralf Labugger; Geoffrey G Hesketh; Christine D'Arsigny; Denis O'Donnell; Nobuko Matsumoto; Christine P Collier; Steve Iscoe; Jennifer E Van Eyk
Differential detection of skeletal troponin I isoforms in serum of a patient with rhabdomyolysis: markers of muscle injury?
Clinical chemistry 2002;48(7):1112-4.
2002: Ralf Labugger; Jason L McDonough; Irina Neverova; Jennifer E Van Eyk
Solubilization, two-dimensional separation and detection of the cardiac myofilament protein troponin T.
Proteomics 2002;2(6):673-8.
2002: David A Colantonio; William Pickett; Robert J Brison; Christine E Collier; Jennifer E Van Eyk
Detection of cardiac troponin I early after onset of chest pain in six patients.
Clinical chemistry 2002;48(4):668-71.
2002: Irina Neverova; Jennifer E Van Eyk
Application of reversed phase high performance liquid chromatography for subproteomic analysis of cardiac muscle.
Proteomics 2002;2(1):22-31.
2001: Jennifer E Van Eyk
Proteomics: unraveling the complexity of heart disease and striving to change cardiology.
Current opinion in molecular therapeutics 2001;3(6):546-53.
2001: Song-Jung Kim; Raymond K Kudej; Atsuko Yatani; Young-Kwon Kim; Gen Takagi; R Honda; David A Colantonio; Jennifer E Van Eyk; Dorothy E Vatner; R L Rasmusson; Stephen F Vatner
A novel mechanism for myocardial stunning involving impaired Ca(2+) handling.
Circulation research 2001;89(9):831-7.
2001: D. Kent Arrell; Irina Neverova; H Fraser; Eduardo Marban; Jennifer E Van Eyk
Proteomic analysis of pharmacologically preconditioned cardiomyocytes reveals novel phosphorylation of myosin light chain 1.
Circulation research 2001;89(6):480-7.
2001: Jennifer E Van Eyk; Anne M Murphy
The role of troponin abnormalities as a cause for stunned myocardium.
Coronary artery disease 2001;12(5):343-7.
2001: D. Kent Arrell; Irina Neverova; Jennifer E Van Eyk
Cardiovascular proteomics: evolution and potential.
Circulation research 2001;88(8):763-73.
2001: G K Davis; Ralf Labugger; Jennifer E Van Eyk; F S Apple
Cardiac troponin T is not detected in Western blots of diseased renal tissue.
Clinical chemistry 2001;47(4):782-3.
2001: Jason L McDonough; Ralf Labugger; W Pickett; M Y Tse; S MacKenzie; Stephen C Pang; Dan Atar; Glorianne Ropchan; Jennifer E Van Eyk
Cardiac troponin I is modified in the myocardium of bypass patients.
Circulation 2001;103(1):58-64.
2000: William Lehman; Victoria Hatch; VL Korman; Michael S Rosol; L Thomas; Robin Maytum; Michael A Geeves; Jennifer E Van Eyk; Larry Tobacman; Roger Craig
Tropomyosin and actin isoforms modulate the localization of tropomyosin strands on actin filaments.
Journal of molecular biology 2000;302(3):593-606.
2000: Ralf Labugger; L Organ; Christine P Collier; Dan Atar; Jennifer E Van Eyk
Extensive troponin I and T modification detected in serum from patients with acute myocardial infarction.
Circulation 2000;102(11):1221-6.
2000: Jeremy A Simpson; Jennifer E Van Eyk; Steve Iscoe
Hypoxemia-induced modification of troponin I and T in canine diaphragm.
Journal of applied physiology (Bethesda, Md. : 1985) 2000;88(2):753-60.
2000: Anne M Murphy; Harald Kögler; Gerasimos F. Kremmydas; Jason L McDonough; David A Kass; Jennifer E Van Eyk; Eduardo Marban
Transgenic mouse model of stunned myocardium.
Science (New York, N.Y.) 2000;287(5452):488-91.
2000: Darren Foster; L H Shen; John Kelly; Pierre Thibault; Jennifer E Van Eyk; Alan S Mak
Phosphorylation of caldesmon by p21-activated kinase. Implications for the Ca(2+) sensitivity of smooth muscle contraction.
The Journal of biological chemistry 2000;275(3):1959-65.
1999: Darren Foster; Jennifer E Van Eyk
In search of the proteins that cause myocardial stunning.
Circulation research 1999;85(5):470-2.
1999: Jason L McDonough; D. Kent Arrell; Jennifer E Van Eyk
Troponin I degradation and covalent complex formation accompanies myocardial ischemia/reperfusion injury.
Circulation research 1999;84(1):9-20.
1998: Jennifer E Van Eyk; D. Kent Arrell; Darren Foster; JD Strauss; T Y Heinonen; Emilia Furmaniak-Kazmierczak; Graham P Côté; Alan S Mak
Different molecular mechanisms for Rho family GTPase-dependent, Ca2+-independent contraction of smooth muscle.
The Journal of biological chemistry 1998;273(36):23433-9.
1998: Jennifer E Van Eyk; FM Powers; W Law; Catherine Larue; R S Hodges; R John Solaro
Breakdown and release of myofilament proteins during ischemia and ischemia/reperfusion in rat hearts: identification of degradation products and effects on the pCa-force relation.
Circulation research 1998;82(2):261-71.
1997: L D Fraker; Jennifer E Van Eyk; R John Solaro
Reversal of phosphate induced decreases in force by the benzimidazole pyridazinone, UD-CG 212 CL, in myofilaments from human ventricle.
Molecular and cellular biochemistry 1997;176(1-2):83-8.
1997: Brian Tripet; Jennifer E Van Eyk; Robert S Hodges
Mapping of a second actin-tropomyosin and a second troponin C binding site within the C terminus of troponin I, and their importance in the Ca2+-dependent regulation of muscle contraction.
Journal of molecular biology 1997;271(5):728-50.
1997: Jennifer E Van Eyk; L T Thomas; Brian Tripet; R J Wiesner; Joyce R Pearlstone; Chuck S Farah; Fernando C Reinach; Robert S Hodges
Distinct regions of troponin I regulate Ca2+-dependent activation and Ca2+ sensitivity of the acto-S1-TM ATPase activity of the thin filament.
The Journal of biological chemistry 1997;272(16):10529-37.
1996: J D Strauss; Jennifer E Van Eyk; Z Barth; L Kluwe; Rudolf J Wiesner; K Maéda; J Caspar Rüegg
Recombinant troponin I substitution and calcium responsiveness in skinned cardiac muscle.
Pflügers Archiv : European journal of physiology 1996;431(6):853-62.
1996: R John Solaro; Jennifer E Van Eyk
Altered interactions among thin filament proteins modulate cardiac function.
Journal of molecular and cellular cardiology 1996;28(2):217-30.
1995: Z Barth; J D Strauss; S Heyder; Jennifer E Van Eyk; Rudolf J Wiesner; J Caspar Rüegg
Ca2+ sensitizing effects of EMD 53998 after troponin replacement in skinned fibres from porcine atria and ventricles.
Pflügers Archiv : European journal of physiology 1995;430(2):220-9.
1995: Jennifer E Van Eyk; R A Caday-Malcolm; L Yu; Randall T Irvin; Robert S Hodges
Anti-peptide monoclonal antibody imaging of a common binding domain involved in muscle regulation.
Protein science : a publication of the Protein Society 1995;4(4):781-90.
1993: Jennifer E Van Eyk; J D Strauss; Robert S Hodges; J Caspar Rüegg
A synthetic peptide mimics troponin I function in the calcium-dependent regulation of muscle contraction.
FEBS letters 1993;323(3):223-8.
1992: A Patricia Campbell; Jennifer E Van Eyk; Robert S Hodges; Brian D Sykes
Interaction of troponin I and troponin C: use of the two-dimensional transferred nuclear Overhauser effect to determine the structure of a Gly-110 inhibitory troponin I peptide analog when bound to cardiac troponin C.
Biochimica et biophysica acta 1992;1160(1):35-54.
1992: J D Strauss; C Zeugner; Jennifer E Van Eyk; C Bletz; M Troschka; J Caspar Rüegg
Troponin replacement in permeabilized cardiac muscle. Reversible extraction of troponin I by incubation with vanadate.
FEBS letters 1992;310(3):229-34.
1992: F D Sönnichsen; Jennifer E Van Eyk; Robert S Hodges; Brian D Sykes
Effect of trifluoroethanol on protein secondary structure: an NMR and CD study using a synthetic actin peptide.
Biochemistry 1992;31(37):8790-8.
1991: Jennifer E Van Eyk; Robert S Hodges
A synthetic peptide of the N-terminus of actin interacts with myosin.
Biochemistry 1991;30(50):11676-82.
1991: Jennifer E Van Eyk; Cyril M Kay; Robert S Hodges
A comparative study of the interactions of synthetic peptides of the skeletal and cardiac troponin I inhibitory region with skeletal and cardiac troponin C.
Biochemistry 1991;30(41):9974-81.
1989: J Caspar Rüegg; C Zeugner; Jennifer E Van Eyk; Cyril M Kay; Robert S Hodges
Inhibition of TnI-TnC interaction and contraction of skinned muscle fibres by the synthetic peptide TnI [104-115].
Pflügers Archiv : European journal of physiology 1989;414(4):430-6.
1988: Jennifer E Van Eyk; Robert S Hodges
The biological importance of each amino acid residue of the troponin I inhibitory sequence 104-115 in the interaction with troponin C and tropomyosin-actin.
The Journal of biological chemistry 1988;263(4):1726-32.
1987: Jennifer E Van Eyk; Robert S Hodges
Calmodulin and troponin C: affinity chromatographic study of divalent cation requirements for troponin I inhibitory peptide (residues 104-115), mastoparan and fluphenazine binding.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1987;65(11):982-8.
1986: P J Cachia; Jennifer E Van Eyk; R H Ingraham; W D McCubbin; C M Kay; R S Hodges
Calmodulin and troponin C: a comparative study of the interaction of mastoparan and troponin I inhibitory peptide [104-115].
Biochemistry 1986;25(12):3553-62.
1985: P J Cachia; Jennifer E Van Eyk; W D McCubbin; C M Kay; R S Hodges
Ion-exchange high-performance liquid chromatographic purification of bovine cardiac and rabbit skeletal muscle troponin subunits.
Journal of chromatography 1985;343(2):315-28.