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Rhona Aird

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TOP 3
Rhona E Aird; M Thomson; Janet S Macpherson; D E Thurston; D I Jodrell; S M Guichard
ABCB1 genetic polymorphism influences the pharmacology of the new pyrrolobenzodiazepine derivative SJG-136.
E R Brown; K A Charles; S A Hoare; R L Rye; Duncan I Jodrell; Rhona E Aird; R Vora; U Prabhakar; M Nakada; R E Corringham; Mark DeWitte; C Sturgeon; D Propper; F R Balkwill; John F Smyth
A clinical study assessing the tolerability and biological effects of infliximab, a TNF-alpha inhibitor, in patients with advanced cancer.
Abraha Habtemariam; Michael Melchart; Rafael Fernandez; Simon Parsons; Iain D H Oswald; Andrew Parkin; Francesca P A Fabbiani; James E Davidson; Alice Dawson; Rhona E Aird; Duncan I Jodrell; Peter J Sadler
Structure-activity relationships for cytotoxic ruthenium(II) arene complexes containing N,N-, N,O-, and O,O-chelating ligands.

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All Publications

2008: Rhona E Aird; M Thomson; Janet S Macpherson; D E Thurston; D I Jodrell; S M Guichard
ABCB1 genetic polymorphism influences the pharmacology of the new pyrrolobenzodiazepine derivative SJG-136.
The pharmacogenomics journal 2008;8(4):289-96.
2008: E R Brown; K A Charles; S A Hoare; R L Rye; Duncan I Jodrell; Rhona E Aird; R Vora; U Prabhakar; M Nakada; R E Corringham; Mark DeWitte; C Sturgeon; D Propper; F R Balkwill; John F Smyth
A clinical study assessing the tolerability and biological effects of infliximab, a TNF-alpha inhibitor, in patients with advanced cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19(7):1340-6.
2006: Abraha Habtemariam; Michael Melchart; Rafael Fernandez; Simon Parsons; Iain D H Oswald; Andrew Parkin; Francesca P A Fabbiani; James E Davidson; Alice Dawson; Rhona E Aird; Duncan I Jodrell; Peter J Sadler
Structure-activity relationships for cytotoxic ruthenium(II) arene complexes containing N,N-, N,O-, and O,O-chelating ligands.
Journal of medicinal chemistry 2006;49(23):6858-68.
2006: Sylvie M Guichard; R Else; E Reid; Benjamin Zeitlin; Rhona E Aird; M Muir; M Dodds; H Fiebig; Peter J Sadler; Duncan I Jodrell
Anti-tumour activity in non-small cell lung cancer models and toxicity profiles for novel ruthenium(II) based organo-metallic compounds.
Biochemical pharmacology 2006;71(4):408-15.
2006: Anna F A Peacock; Abraha Habtemariam; Rafael Fernández; Victoria Walland; Francesca P A Fabbiani; Simon Parsons; Rhona E Aird; Duncan I Jodrell; Peter J Sadler
Tuning the reactivity of osmium(II) and ruthenium(II) arene complexes under physiological conditions.
Journal of the American Chemical Society 2006;128(5):1739-48.
2005: Fuyi Wang; Abraha Habtemariam; Erwin P L van der Geer; Rafael Fernández; Michael Melchart; Robert J Deeth; Rhona E Aird; Sylvie M Guichard; Francesca P A Fabbiani; Patricia Lozano-Casal; Iain D H Oswald; Duncan I Jodrell; Simon Parsons; Peter J Sadler
Controlling ligand substitution reactions of organometallic complexes: tuning cancer cell cytotoxicity.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(51):18269-74.
2005: Richard L Hayward; Q C Schornagel; R Tente; Janet S Macpherson; Rhona E Aird; Sylvie M Guichard; Abraha Habtemariam; Peter J Sadler; Duncan I Jodrell
Investigation of the role of Bax, p21/Waf1 and p53 as determinants of cellular responses in HCT116 colorectal cancer cells exposed to the novel cytotoxic ruthenium(II) organometallic agent, RM175.
Cancer chemotherapy and pharmacology 2005;55(6):577-83.
2002: Rhona E Aird; Jeff Cummings; AA Ritchie; M Muir; Robert E Morris; Haimei Chen; Peter J Sadler; Duncan I Jodrell
In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer.
British journal of cancer 2002;86(10):1652-7.
2001: Robert E Morris; Rhona E Aird; P del S Murdoch; Haimei Chen; Jeff Cummings; N D Hughes; Simon Parsons; Andrew Parkin; G Boyd; Duncan I Jodrell; Peter J Sadler
Inhibition of cancer cell growth by ruthenium(II) arene complexes.
Journal of medicinal chemistry 2001;44(22):3616-21.
2001: Duncan I Jodrell; Moira Stewart; Rhona E Aird; Gillian Knowles; Angela Bowman; L Wall; C McLean
5-fluorouracil steady state pharmacokinetics and outcome in patients receiving protracted venous infusion for advanced colorectal cancer.
British journal of cancer 2001;84(5):600-3.