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Yvette van Kooyk

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Anatomy

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Mice
HIV-1

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Amino Acid Sequence

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Co-Publications
Name
63
Geijtenbeek, Teunis
45
Figdor, Carl
36
van Vliet, Sandra
15
Engering, Anneke
10
Appelmelk, Ben
9
van Duijnhoven, Gerard
9
Garcia Vallejo, Juan Jesus
8
Van Die, Irma
8
Koppel, Estella
7
Ludwig, Irene
7
van Liempt, Ellis
7
Saeland, Eirikur
6
van Gisbergen, Klaas
6
Bleijs, DA
5
Aarnoudse, Corlien

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Publications

TOP 3
van Vliet Sandra J; Steeghs Liana; Bruijns Sven C M; Vaezirad Medi M; Snijders Blok Christian; Arenas Busto Jésus A; Deken Marcel; van Putten Jos P M; van Kooyk Yvette
Variation of Neisseria gonorrhoeae lipooligosaccharide directs dendritic cell-induced T helper responses.
Chamorro Sonia; García-Vallejo Juan J; Unger Wendy W J; Fernandes Rosette J; Bruijns Sven C M; Laban Sandra; Roep Bart O; 't Hart Bert A; van Kooyk Yvette
TLR triggering on tolerogenic dendritic cells results in TLR2 up-regulation and a reduced proinflammatory immune program.
García-Vallejo Juan J; van Kooyk Yvette
Endogenous ligands for C-type lectin receptors: the true regulators of immune homeostasis.

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All Publications

2009: van Vliet Sandra J; Steeghs Liana; Bruijns Sven C M; Vaezirad Medi M; Snijders Blok Christian; Arenas Busto Jésus A; Deken Marcel; van Putten Jos P M; van Kooyk Yvette
Variation of Neisseria gonorrhoeae lipooligosaccharide directs dendritic cell-induced T helper responses.
PLoS pathogens 2009;5(10):e1000625.
2009: Chamorro Sonia; García-Vallejo Juan J; Unger Wendy W J; Fernandes Rosette J; Bruijns Sven C M; Laban Sandra; Roep Bart O; 't Hart Bert A; van Kooyk Yvette
TLR triggering on tolerogenic dendritic cells results in TLR2 up-regulation and a reduced proinflammatory immune program.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(5):2984-94.
2009: García-Vallejo Juan J; van Kooyk Yvette
Endogenous ligands for C-type lectin receptors: the true regulators of immune homeostasis.
Immunological reviews 2009;230(1):22-37.
2009: Saeland Eirikur; de Jong Marein A W P; Nabatov Alexey A; Kalay Hakan; Geijtenbeek Teunis B H; van Kooyk Yvette
MUC1 in human milk blocks transmission of human immunodeficiency virus from dendritic cells to T cells.
Molecular immunology 2009;46(11-12):2309-16.
2009: Singh Satwinder Kaur; Streng-Ouwehand Ingeborg; Litjens Manja; Weelij Danny R; García-Vallejo Juan Jesús; van Vliet Sandra J; Saeland Eirikur; van Kooyk Yvette
Characterization of murine MGL1 and MGL2 C-type lectins: distinct glycan specificities and tumor binding properties.
Molecular immunology 2009;46(6):1240-9.
2009: De Koker Stefaan; De Geest Bruno G; Singh Satwinder K; De Rycke Riet; Naessens Thomas; Van Kooyk Yvette; Demeester Jo; De Smedt Stefaan C; Grooten Johan
Polyelectrolyte microcapsules as antigen delivery vehicles to dendritic cells: uptake, processing, and cross-presentation of encapsulated antigens.
Angewandte Chemie (International ed. in English) 2009;48(45):8485-9.
2009: Bax Marieke; van Vliet Sandra J; Litjens Manja; García-Vallejo Juan J; van Kooyk Yvette
Interaction of polysialic acid with CCL21 regulates the migratory capacity of human dendritic cells.
PloS one 2009;4(9):e6987.
2008: Charoensap Jaruek; Engering Anneke; Utaisincharoen Pongsak; van Kooyk Yvette; Sirisinha Stitaya
Activation of human monocyte-derived dendritic cells by Burkholderia pseudomallei does not require binding to the C-type lectin DC-SIGN.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2008;102 Suppl 1():S76-81.
2008: Konstantinov Sergey R; Smidt Hauke; de Vos Willem M; Bruijns Sven C M; Singh Satwinder Kaur; Valence Florence; Molle Daniel; Lortal Sylvie; Altermann Eric; Klaenhammer Todd R; van Kooyk Yvette
S layer protein A of Lactobacillus acidophilus NCFM regulates immature dendritic cell and T cell functions.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(49):19474-9.
2008: van Kooyk Yvette
C-type lectins on dendritic cells: key modulators for the induction of immune responses.
Biochemical Society transactions 2008;36(Pt 6):1478-81.
2008: de Jong Marein A W P; de Witte Lot; Bolmstedt Anders; van Kooyk Yvette; Geijtenbeek Teunis B H
Dendritic cells mediate herpes simplex virus infection and transmission through the C-type lectin DC-SIGN.
The Journal of general virology 2008;89(Pt 10):2398-409.
2008: van Vliet Sandra J; García-Vallejo Juan J; van Kooyk Yvette
Dendritic cells and C-type lectin receptors: coupling innate to adaptive immune responses.
Immunology and cell biology 2008;86(7):580-7.
2008: van Vliet Sandra J; Paessens Lutz C; Broks-van den Berg Venice C M; Geijtenbeek Teunis B H; van Kooyk Yvette
The C-type lectin macrophage galactose-type lectin impedes migration of immature APCs.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(5):3148-55.
2008: Gaudart Narintorn; Ekpo Pattama; Pattanapanyasat Kovit; van Kooyk Yvette; Engering Anneke
Leptospira interrogans is recognized through DC-SIGN and induces maturation and cytokine production by human dendritic cells.
FEMS immunology and medical microbiology 2008;53(3):359-67.
2008: van Kooyk Yvette; Rabinovich Gabriel A
Protein-glycan interactions in the control of innate and adaptive immune responses.
Nature immunology 2008;9(6):593-601.
2008: Koppel Estella A; Litjens Manja; van den Berg Venice C; van Kooyk Yvette; Geijtenbeek Teunis B H
Interaction of SIGNR1 expressed by marginal zone macrophages with marginal zone B cells is essential to early IgM responses against Streptococcus pneumoniae.
Molecular immunology 2008;45(10):2881-7.
2008: García-Vallejo Juan J; van Liempt Ellis; da Costa Martins Paula; Beckers Cora; van het Hof Bert; Gringhuis Sonja I; Zwaginga Jaap-Jan; van Dijk Willem; Geijtenbeek Teunis B H; van Kooyk Yvette; van Die Irma
DC-SIGN mediates adhesion and rolling of dendritic cells on primary human umbilical vein endothelial cells through LewisY antigen expressed on ICAM-2.
Molecular immunology 2008;45(8):2359-69.
2008: Appelmelk B J; den Dunnen J; Driessen N N; Ummels R; Pak M; Nigou J; Larrouy-Maumus G; Gurcha S S; Movahedzadeh F; Geurtsen J; Brown E J; Eysink Smeets M M; Besra G S; Willemsen P T J; Lowary T L; van Kooyk Y; Maaskant J J; Stoker N G; van der Ley P; Puzo G; Vandenbroucke-Grauls C M J E; Wieland C W; van der Poll T; Geijtenbeek T B H; van der Sar A M; Bitter W
The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction.
Cellular microbiology 2008;10(4):930-44.
2008: van Vliet Sandra J; Saeland Eirikur; van Kooyk Yvette
Sweet preferences of MGL: carbohydrate specificity and function.
Trends in immunology 2008;29(2):83-90.
2008: Aarnoudse Corlien A; Bax Marieke; Sánchez-Hernández Marta; García-Vallejo Juan J; van Kooyk Yvette
Glycan modification of the tumor antigen gp100 targets DC-SIGN to enhance dendritic cell induced antigen presentation to T cells.
International journal of cancer. Journal international du cancer 2008;122(4):839-46.
2008: Paessens L C; Fluitsma D M; van Kooyk Y
Haematopoietic antigen-presenting cells in the human thymic cortex: evidence for a role in selection and removal of apoptotic thymocytes.
The Journal of pathology 2008;214(1):96-103.
2008: Paessens Lutz C; Singh Satwinder K; Fernandes Rosette J; van Kooyk Yvette
Vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1) provide co-stimulation in positive selection along with survival of selected thymocytes.
Molecular immunology 2008;45(1):42-8.
2007: Bax Marieke; García-Vallejo Juan J; Jang-Lee Jihye; North Simon J; Gilmartin Tim J; Hernández Gilberto; Crocker Paul R; Leffler Hakon; Head Steven R; Haslam Stuart M; Dell Anne; van Kooyk Yvette
Dendritic cell maturation results in pronounced changes in glycan expression affecting recognition by siglecs and galectins.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(12):8216-24.
2007: van Vliet Sandra J; den Dunnen Jeroen; Gringhuis Sonja I; Geijtenbeek Teunis Bh; van Kooyk Yvette
Innate signaling and regulation of Dendritic cell immunity.
Current opinion in immunology 2007;19(4):435-40.
2007: van Vliet Sandra J; Aarnoudse Corlien A; Broks-van den Berg Venice C M; Boks Martine; Geijtenbeek Teunis B H; van Kooyk Yvette
MGL-mediated internalization and antigen presentation by dendritic cells: a role for tyrosine-5.
European journal of immunology 2007;37(8):2075-81.
2007: Saeland Eirikur; van Vliet Sandra J; Bäckström Malin; van den Berg Venice C M; Geijtenbeek Teunis B H; Meijer Gerrit A; van Kooyk Yvette
The C-type lectin MGL expressed by dendritic cells detects glycan changes on MUC1 in colon carcinoma.
Cancer immunology, immunotherapy : CII 2007;56(8):1225-36.
2007: Paessens Lutz C; García-Vallejo Juan J; Fernandes Rosette J; van Kooyk Yvette
The glycosylation of thymic microenvironments. A microscopic study using plant lectins.
Immunology letters 2007;110(1):65-73.
2007: Gringhuis Sonja I; den Dunnen Jeroen; Litjens Manja; van Het Hof Bert; van Kooyk Yvette; Geijtenbeek Teunis B H
C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaB.
Immunity 2007;26(5):605-16.
2007: van Liempt Ellis; van Vliet Sandra J; Engering Anneke; García Vallejo Juan Jesus; Bank Christine M C; Sanchez-Hernandez Marta; van Kooyk Yvette; van Die Irma
Schistosoma mansoni soluble egg antigens are internalized by human dendritic cells through multiple C-type lectins and suppress TLR-induced dendritic cell activation.
Molecular immunology 2007;44(10):2605-15.
2007: de Witte Lot; Nabatov Alexey; Pion Marjorie; Fluitsma Donna; de Jong Marein A W P; de Gruijl Tanja; Piguet Vincent; van Kooyk Yvette; Geijtenbeek Teunis B H
Langerin is a natural barrier to HIV-1 transmission by Langerhans cells.
Nature medicine 2007;13(3):367-71.
2007: Wieland Catharina W; Koppel Estella A; den Dunnen Jeroen; Florquin Sandrine; McKenzie Andrew N J; van Kooyk Yvette; van der Poll Tom; Geijtenbeek Teunis B H
Mice lacking SIGNR1 have stronger T helper 1 responses to Mycobacterium tuberculosis.
Microbes and infection / Institut Pasteur 2007;9(2):134-41.
2007: de Witte Lot; Zoughlami Younes; Aengeneyndt Birgit; David Guido; van Kooyk Yvette; Gissmann Lutz; Geijtenbeek Teunis B H
Binding of human papilloma virus L1 virus-like particles to dendritic cells is mediated through heparan sulfates and induces immune activation.
Immunobiology 2007;212(9-10):679-91.
2006: van Vliet Sandra J; Gringhuis Sonja I; Geijtenbeek Teunis B H; van Kooyk Yvette
Regulation of effector T cells by antigen-presenting cells via interaction of the C-type lectin MGL with CD45.
Nature immunology 2006;7(11):1200-8.
2006: van Kooyk Yvette; Geijtenbeek Teunis B H
Toll-like receptors keep antigen sorting on the right track.
Immunity 2006;25(4):525-7.
2006: Ludwig Irene S; Geijtenbeek Teunis B H; van Kooyk Yvette
Two way communication between neutrophils and dendritic cells.
Current opinion in pharmacology 2006;6(4):408-13.
2006: Grün Christian H; van Vliet Sandra J; Schiphorst Wietske E C M; Bank Christine M C; Meyer Sandra; van Die Irma; van Kooyk Yvette
One-step biotinylation procedure for carbohydrates to study carbohydrate-protein interactions.
Analytical biochemistry 2006;354(1):54-63.
2006: Lekkerkerker Annemarie N; van Kooyk Yvette; Geijtenbeek Teunis B H
Viral piracy: HIV-1 targets dendritic cells for transmission.
Current HIV research 2006;4(2):169-76.
2006: de Witte Lot; Abt Marion; Schneider-Schaulies Sibylle; van Kooyk Yvette; Geijtenbeek Teunis B H
Measles virus targets DC-SIGN to enhance dendritic cell infection.
Journal of virology 2006;80(7):3477-86.
2006: Wiedemann Agnès; Patel Jayesh C; Lim Jenson; Tsun Andy; van Kooyk Yvette; Caron Emmanuelle
Two distinct cytoplasmic regions of the beta2 integrin chain regulate RhoA function during phagocytosis.
The Journal of cell biology 2006;172(7):1069-79.
2006: Steeghs Liana; van Vliet Sandra J; Uronen-Hansson Heli; van Mourik Andries; Engering Anneke; Sanchez-Hernandez Martha; Klein Nigel; Callard Robin; van Putten Jos P M; van der Ley Peter; van Kooyk Yvette; van de Winkel Jan G J
Neisseria meningitidis expressing lgtB lipopolysaccharide targets DC-SIGN and modulates dendritic cell function.
Cellular microbiology 2006;8(2):316-25.
2006: Bergman Mathijs; Del Prete Gianfranco; van Kooyk Yvette; Appelmelk Ben
Helicobacter pylori phase variation, immune modulation and gastric autoimmunity.
Nature reviews. Microbiology 2006;4(2):151-9.
2006: Aarnoudse Corlien A; Garcia Vallejo Juan J; Saeland Eiríkur; van Kooyk Yvette
Recognition of tumor glycans by antigen-presenting cells.
Current opinion in immunology 2006;18(1):105-11.
2006: van Vliet Sandra J; van Liempt Ellis; Geijtenbeek Teunis B H; van Kooyk Yvette
Differential regulation of C-type lectin expression on tolerogenic dendritic cell subsets.
Immunobiology 2006;211(6-8):577-85.
2005: van Gisbergen Klaas P J M; Geijtenbeek Teunis B H; van Kooyk Yvette
Close encounters of neutrophils and DCs.
Trends in immunology 2005;26(12):626-31.
2005: van Gisbergen Klaas P J M; Ludwig Irene S; Geijtenbeek Teunis B H; van Kooyk Yvette
Interactions of DC-SIGN with Mac-1 and CEACAM1 regulate contact between dendritic cells and neutrophils.
FEBS letters 2005;579(27):6159-68.
2005: Meyer Sandra; van Liempt Ellis; Imberty Anne; van Kooyk Yvette; Geyer Hildegard; Geyer Rudolf; van Die Irma
DC-SIGN mediates binding of dendritic cells to authentic pseudo-LewisY glycolipids of Schistosoma mansoni cercariae, the first parasite-specific ligand of DC-SIGN.
The Journal of biological chemistry 2005;280(45):37349-59.
2005: Koppel Estella A; Wieland Catharina W; van den Berg Venice C M; Litjens Manja; Florquin Sandrine; van Kooyk Yvette; van der Poll Tom; Geijtenbeek Teunis B H
Specific ICAM-3 grabbing nonintegrin-related 1 (SIGNR1) expressed by marginal zone macrophages is essential for defense against pulmonary Streptococcus pneumoniae infection.
European journal of immunology 2005;35(10):2962-9.
2005: van Gisbergen Klaas P J M; Aarnoudse Corlien A; Meijer Gerrit A; Geijtenbeek Teunis B H; van Kooyk Yvette
Dendritic cells recognize tumor-specific glycosylation of carcinoembryonic antigen on colorectal cancer cells through dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin.
Cancer research 2005;65(13):5935-44.
2005: Smits Hermelijn H; Engering Anneke; van der Kleij Desiree; de Jong Esther C; Schipper Kim; van Capel Toni M M; Zaat Bas A J; Yazdanbakhsh Maria; Wierenga Eddy A; van Kooyk Yvette; Kapsenberg Martien L
Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin.
The Journal of allergy and clinical immunology 2005;115(6):1260-7.
2005: van Vliet Sandra J; van Liempt Ellis; Saeland Eirikur; Aarnoudse Corlien A; Appelmelk Ben; Irimura Tatsuro; Geijtenbeek Teunis B H; Blixt Ola; Alvarez Richard; van Die Irma; van Kooyk Yvette
Carbohydrate profiling reveals a distinctive role for the C-type lectin MGL in the recognition of helminth parasites and tumor antigens by dendritic cells.
International immunology 2005;17(5):661-9.
2005: van Gisbergen Klaas P J M; Sanchez-Hernandez Marta; Geijtenbeek Teunis B H; van Kooyk Yvette
Neutrophils mediate immune modulation of dendritic cells through glycosylation-dependent interactions between Mac-1 and DC-SIGN.
The Journal of experimental medicine 2005;201(8):1281-92.
2005: van Gisbergen Klaas P J M; Paessens Lutz C; Geijtenbeek Teunis B H; van Kooyk Yvette
Molecular mechanisms that set the stage for DC-T cell engagement.
Immunology letters 2005;97(2):199-208.
2005: Groot Fedde; Geijtenbeek Teunis B H; Sanders Rogier W; Baldwin Christopher E; Sanchez-Hernandez Marta; Floris René; van Kooyk Yvette; de Jong Esther C; Berkhout Ben
Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN--gp120 interaction.
Journal of virology 2005;79(5):3009-15.
2005: Koppel Estella A; van Gisbergen Klaas P J M; Geijtenbeek Teunis B H; van Kooyk Yvette
Distinct functions of DC-SIGN and its homologues L-SIGN (DC-SIGNR) and mSIGNR1 in pathogen recognition and immune regulation.
Cellular microbiology 2005;7(2):157-65.
2005: Koppel Estella A; Saeland Eirikur; de Cooker Désirée J M; van Kooyk Yvette; Geijtenbeek Teunis B H
DC-SIGN specifically recognizes Streptococcus pneumoniae serotypes 3 and 14.
Immunobiology 2005;210(2-4):203-10.
2005: Koppel Estella A; Ludwig Irene S; Appelmelk Ben J; van Kooyk Yvette; Geijtenbeek Teunis B H
Carbohydrate specificities of the murine DC-SIGN homologue mSIGNR1.
Immunobiology 2005;210(2-4):195-201.
2004: Martin Maureen P; Lederman Michael M; Hutcheson Holli B; Goedert James J; Nelson George W; van Kooyk Yvette; Detels Roger; Buchbinder Susan; Hoots Keith; Vlahov David; O'Brien Stephen J; Carrington Mary
Association of DC-SIGN promoter polymorphism with increased risk for parenteral, but not mucosal, acquisition of human immunodeficiency virus type 1 infection.
Journal of virology 2004;78(24):14053-6.
2004: Arrighi Jean-François; Pion Marjorie; Garcia Eduardo; Escola Jean-Michel; van Kooyk Yvette; Geijtenbeek Teunis B; Piguet Vincent
DC-SIGN-mediated infectious synapse formation enhances X4 HIV-1 transmission from dendritic cells to T cells.
The Journal of experimental medicine 2004;200(10):1279-88.
2004: Lekkerkerker Annemarie N; Ludwig Irene S; van Vliet Sandra J; van Kooyk Yvette; Geijtenbeek Teunis B H
Potency of HIV-1 envelope glycoprotein gp120 antibodies to inhibit the interaction of DC-SIGN with HIV-1 gp120.
Virology 2004;329(2):465-76.
2004: Bergman Mathijs P; Engering Anneke; Smits Hermelijn H; van Vliet Sandra J; van Bodegraven Ad A; Wirth Hans-Peter; Kapsenberg Martien L; Vandenbroucke-Grauls Christina M J E; van Kooyk Yvette; Appelmelk Ben J
Helicobacter pylori modulates the T helper cell 1/T helper cell 2 balance through phase-variable interaction between lipopolysaccharide and DC-SIGN.
The Journal of experimental medicine 2004;200(8):979-90.
2004: Arrighi Jean-François; Pion Marjorie; Wiznerowicz Maciej; Geijtenbeek Teunis B; Garcia Eduardo; Abraham Shahnaz; Leuba Florence; Dutoit Valérie; Ducrey-Rundquist Odile; van Kooyk Yvette; Trono Didier; Piguet Vincent
Lentivirus-mediated RNA interference of DC-SIGN expression inhibits human immunodeficiency virus transmission from dendritic cells to T cells.
Journal of virology 2004;78(20):10848-55.
2004: Lekkerkerker Annemarie N; Van Kooyk Yvette; Geijtenbeek Teunis B H
Mucosal-targeted AIDS vaccines: the next generation?
Trends in microbiology 2004;12(10):447-50.
2004: 't Hart Bert A; Laman Jon D; Bauer Jan; Blezer Erwin; van Kooyk Yvette; Hintzen Rogier Q
Modelling of multiple sclerosis: lessons learned in a non-human primate.
Lancet neurology 2004;3(10):588-97.
2004: Ludwig Irene S; Lekkerkerker Annemarie N; Depla Erik; Bosman Fons; Musters René J P; Depraetere Stany; van Kooyk Yvette; Geijtenbeek Teunis B H
Hepatitis C virus targets DC-SIGN and L-SIGN to escape lysosomal degradation.
Journal of virology 2004;78(15):8322-32.
2004: van Kooyk Yvette; Engering Anneke; Lekkerkerker Annemarie N; Ludwig Irene S; Geijtenbeek Teunis B H
Pathogens use carbohydrates to escape immunity induced by dendritic cells.
Current opinion in immunology 2004;16(4):488-93.
2004: Van Liempt Ellis; Imberty Anne; Bank Christine M C; Van Vliet Sandra J; Van Kooyk Yvette; Geijtenbeek Teunis B H; Van Die Irma
Molecular basis of the differences in binding properties of the highly related C-type lectins DC-SIGN and L-SIGN to Lewis X trisaccharide and Schistosoma mansoni egg antigens.
The Journal of biological chemistry 2004;279(32):33161-7.
2004: 't Hart Bert A; van Kooyk Yvette
Yin-Yang regulation of autoimmunity by DCs.
Trends in immunology 2004;25(7):353-9.
2004: Engering Anneke; van Vliet Sandra J; Hebeda Konnie; Jackson David G; Prevo Remko; Singh Satwinder K; Geijtenbeek Teunis B H; van Krieken Han; van Kooyk Yvette
Dynamic populations of dendritic cell-specific ICAM-3 grabbing nonintegrin-positive immature dendritic cells and liver/lymph node-specific ICAM-3 grabbing nonintegrin-positive endothelial cells in the outer zones of the paracortex of human lymph nodes.
The American journal of pathology 2004;164(5):1587-95.
2004: Ploquin Mickaël J-Y; Diop Ousmane M; Sol-Foulon Nathalie; Mortara Lorenzo; Faye Abdourahmane; Soares Marcelo A; Nerrienet Eric; Le Grand Roger; Van Kooyk Yvette; Amara Ali; Schwartz Olivier; Barré-Sinoussi Françoise; Müller-Trutwin Michaela C
DC-SIGN from African green monkeys is expressed in lymph nodes and mediates infection in trans of simian immunodeficiency virus SIVagm.
Journal of virology 2004;78(2):798-810.
2004: Koppel Estella A; Ludwig Irene S; Hernandez Marta Sanchez; Lowary Todd L; Gadikota Rajendrakumar R; Tuzikov Alexander B; Vandenbroucke-Grauls Christina M J E; van Kooyk Yvette; Appelmelk Ben J; Geijtenbeek Teunis B H
Identification of the mycobacterial carbohydrate structure that binds the C-type lectins DC-SIGN, L-SIGN and SIGNR1.
Immunobiology 2004;209(1-2):117-27.
2004: Geijtenbeek Teunis B H; van Vliet Sandra J; Engering Anneke; 't Hart Bert A; van Kooyk Yvette
Self- and nonself-recognition by C-type lectins on dendritic cells.
Annual review of immunology 2004;22():33-54.
2003: van Kooyk Yvette; Geijtenbeek Teunis B H
DC-SIGN: escape mechanism for pathogens.
Nature reviews. Immunology 2003;3(9):697-709.
2003: Geijtenbeek Teunis B H; van Kooyk Yvette
Pathogens target DC-SIGN to influence their fate DC-SIGN functions as a pathogen receptor with broad specificity.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003;111(7-8):698-714.
2003: van Die Irma; van Vliet Sandra J; Nyame A Kwame; Cummings Richard D; Bank Christine M C; Appelmelk Ben; Geijtenbeek Teunis B H; van Kooyk Yvette
The dendritic cell-specific C-type lectin DC-SIGN is a receptor for Schistosoma mansoni egg antigens and recognizes the glycan antigen Lewis x.
Glycobiology 2003;13(6):471-8.
2003: van Kooyk Yvette; Appelmelk Ben; Geijtenbeek Teunis B H
A fatal attraction: Mycobacterium tuberculosis and HIV-1 target DC-SIGN to escape immune surveillance.
Trends in molecular medicine 2003;9(4):153-9.
2003: Kämmerer Ulrike; Eggert Andreas O; Kapp Michaela; McLellan Alexander D; Geijtenbeek Teunis B H; Dietl Johannes; van Kooyk Yvette; Kämpgen Eckhart
Unique appearance of proliferating antigen-presenting cells expressing DC-SIGN (CD209) in the decidua of early human pregnancy.
The American journal of pathology 2003;162(3):887-96.
2003: Appelmelk Ben J; van Die Irma; van Vliet Sandra J; Vandenbroucke-Grauls Christina M J E; Geijtenbeek Teunis B H; van Kooyk Yvette
Cutting edge: carbohydrate profiling identifies new pathogens that interact with dendritic cell-specific ICAM-3-grabbing nonintegrin on dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(4):1635-9.
2003: te Velde Anje A; van Kooyk Yvette; Braat Henri; Hommes Daan W; Dellemijn Trees A M; Slors J Frederik M; van Deventer Sander J H; Vyth-Dreese Florry A
Increased expression of DC-SIGN+IL-12+IL-18+ and CD83+IL-12-IL-18- dendritic cell populations in the colonic mucosa of patients with Crohn's disease.
European journal of immunology 2003;33(1):143-51.
2003: Geijtenbeek Teunis B H; Van Vliet Sandra J; Koppel Estella A; Sanchez-Hernandez Marta; Vandenbroucke-Grauls Christine M J E; Appelmelk Ben; Van Kooyk Yvette
Mycobacteria target DC-SIGN to suppress dendritic cell function.
The Journal of experimental medicine 2003;197(1):7-17.
2003: Geijtenbeek T B H; van Kooyk Y
DC-SIGN: a novel HIV receptor on DCs that mediates HIV-1 transmission.
Current topics in microbiology and immunology 2003;276():31-54.
2002: Geijtenbeek Teunis B H; Groot Peter C; Nolte Martijn A; van Vliet Sandra J; Gangaram-Panday Shanti T; van Duijnhoven Gerard C F; Kraal Georg; van Oosterhout Antoon J M; van Kooyk Yvette
Marginal zone macrophages express a murine homologue of DC-SIGN that captures blood-borne antigens in vivo.
Blood 2002;100(8):2908-16.
2002: Engering Anneke; Geijtenbeek Teunis B H; van Kooyk Yvette
Immune escape through C-type lectins on dendritic cells.
Trends in immunology 2002;23(10):480-5.
2002: Shamri Revital; Grabovsky Valentin; Feigelson Sara W; Dwir Oren; Van Kooyk Yvette; Alon Ronen
Chemokine stimulation of lymphocyte alpha 4 integrin avidity but not of leukocyte function-associated antigen-1 avidity to endothelial ligands under shear flow requires cholesterol membrane rafts.
The Journal of biological chemistry 2002;277(42):40027-35.
2002: Engering Anneke; Van Vliet Sandra J; Geijtenbeek Teunis B H; Van Kooyk Yvette
Subset of DC-SIGN(+) dendritic cells in human blood transmits HIV-1 to T lymphocytes.
Blood 2002;100(5):1780-6.
2002: van Kooyk Yvette; Geijtenbeek Teunis B H
A novel adhesion pathway that regulates dendritic cell trafficking and T cell interactions.
Immunological reviews 2002;186():47-56.
2002: Velders Gerjo A; Pruijt Johannes F M; Verzaal Perry; van Os Ronald; van Kooyk Yvette; Figdor Carl G; de Kruijf Evert-Jan F M; Willemze Roel; Fibbe Willem E
Enhancement of G-CSF-induced stem cell mobilization by antibodies against the beta 2 integrins LFA-1 and Mac-1.
Blood 2002;100(1):327-33.
2002: Geijtenbeek Teunis B H; Engering Anneke; Van Kooyk Yvette
DC-SIGN, a C-type lectin on dendritic cells that unveils many aspects of dendritic cell biology.
Journal of leukocyte biology 2002;71(6):921-31.
2002: Loré Karin; Sönnerborg Anders; Broström Christina; Goh Li-Ean; Perrin Luc; McDade Hugh; Stellbrink Hans-Jürgen; Gazzard Brian; Weber Rainer; Napolitano Laura A; van Kooyk Yvette; Andersson Jan
Accumulation of DC-SIGN+CD40+ dendritic cells with reduced CD80 and CD86 expression in lymphoid tissue during acute HIV-1 infection.
AIDS (London, England) 2002;16(5):683-92.
2002: Engering Anneke; Geijtenbeek Teunis B H; van Vliet Sandra J; Wijers Mietske; van Liempt Ellis; Demaurex Nicolas; Lanzavecchia Antonio; Fransen Jack; Figdor Carl G; Piguet Vincent; van Kooyk Yvette
The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(5):2118-26.
2002: Geijtenbeek Teunis B H; van Duijnhoven Gerard C F; van Vliet Sandra J; Krieger Elmar; Vriend Gert; Figdor Carl G; van Kooyk Yvette
Identification of different binding sites in the dendritic cell-specific receptor DC-SIGN for intercellular adhesion molecule 3 and HIV-1.
The Journal of biological chemistry 2002;277(13):11314-20.
2002: Figdor Carl G; van Kooyk Yvette; Adema Gosse J
C-type lectin receptors on dendritic cells and Langerhans cells.
Nature reviews. Immunology 2002;2(2):77-84.
2002: Smits Hermelijn H; de Jong Esther C; Schuitemaker Joost H N; Geijtenbeek Theo B H; van Kooyk Yvette; Kapsenberg Martien L; Wierenga Eddy A
Intercellular adhesion molecule-1/LFA-1 ligation favors human Th1 development.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1710-6.
2002: Sol-Foulon Nathalie; Moris Arnaud; Nobile Cinzia; Boccaccio Claire; Engering Anneke; Abastado Jean-Pierre; Heard Jean-Michel; van Kooyk Yvette; Schwartz Olivier
HIV-1 Nef-induced upregulation of DC-SIGN in dendritic cells promotes lymphocyte clustering and viral spread.
Immunity 2002;16(1):145-55.
2001: Geijtenbeek T B; Koopman G; van Duijnhoven G C; van Vliet S J; van Schijndel A C; Engering A; Heeney J L; van Kooyk Y
Rhesus macaque and chimpanzee DC-SIGN act as HIV/SIV gp120 trans-receptors, similar to human DC-SIGN.
Immunology letters 2001;79(1-2):101-7.
2001: Wagener F A; Eggert A; Boerman O C; Oyen W J; Verhofstad A; Abraham N G; Adema G; van Kooyk Y; de Witte T; Figdor C G
Heme is a potent inducer of inflammation in mice and is counteracted by heme oxygenase.
Blood 2001;98(6):1802-11.
2001: Bleijs D A; Geijtenbeek T B; Figdor C G; van Kooyk Y
DC-SIGN and LFA-1: a battle for ligand.
Trends in immunology 2001;22(8):457-63.
2001: Geijtenbeek T B; van Vliet S J; van Duijnhoven G C; Figdor C G; van Kooyk Y
DC-SIGN, a dentritic cell-specific HIV-1 receptor present in placenta that infects T cells in trans-a review.
Placenta 2001;22 Suppl A():S19-23.
2001: Bashirova A A; Geijtenbeek T B; van Duijnhoven G C; van Vliet S J; Eilering J B; Martin M P; Wu L; Martin T D; Viebig N; Knolle P A; KewalRamani V N; van Kooyk Y; Carrington M
A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection.
The Journal of experimental medicine 2001;193(6):671-8.
2001: Bleijs D A; van Duijnhoven G C; van Vliet S J; Thijssen J P; Figdor C G; van Kooyk Y
A single amino acid in the cytoplasmic domain of the beta 2 integrin lymphocyte function-associated antigen-1 regulates avidity-dependent inside-out signaling.
The Journal of biological chemistry 2001;276(13):10338-46.
2000: Geijtenbeek T B; Krooshoop D J; Bleijs D A; van Vliet S J; van Duijnhoven G C; Grabovsky V; Alon R; Figdor C G; van Kooyk Y
DC-SIGN-ICAM-2 interaction mediates dendritic cell trafficking.
Nature immunology 2000;1(4):353-7.
2000: van Kooyk Y; Figdor C G
Avidity regulation of integrins: the driving force in leukocyte adhesion.
Current opinion in cell biology 2000;12(5):542-7.
2000: Sigal A; Bleijs D A; Grabovsky V; van Vliet S J; Dwir O; Figdor C G; van Kooyk Y; Alon R
The LFA-1 integrin supports rolling adhesions on ICAM-1 under physiological shear flow in a permissive cellular environment.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(1):442-52.
2000: Nelissen J M; Peters I M; de Grooth B G; van Kooyk Y; Figdor C G
Dynamic regulation of activated leukocyte cell adhesion molecule-mediated homotypic cell adhesion through the actin cytoskeleton.
Molecular biology of the cell 2000;11(6):2057-68.
2000: Nelissen J M; Torensma R; Pluyter M; Adema G J; Raymakers R A; van Kooyk Y; Figdor C G
Molecular analysis of the hematopoiesis supporting osteoblastic cell line U2-OS.
Experimental hematology 2000;28(4):422-32.
2000: Reedquist K A; Ross E; Koop E A; Wolthuis R M; Zwartkruis F J; van Kooyk Y; Salmon M; Buckley C D; Bos J L
The small GTPase, Rap1, mediates CD31-induced integrin adhesion.
The Journal of cell biology 2000;148(6):1151-8.
2000: Geijtenbeek T B; Kwon D S; Torensma R; van Vliet S J; van Duijnhoven G C; Middel J; Cornelissen I L; Nottet H S; KewalRamani V N; Littman D R; Figdor C G; van Kooyk Y
DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells.
Cell 2000;100(5):587-97.
2000: Geijtenbeek T B; Torensma R; van Vliet S J; van Duijnhoven G C; Adema G J; van Kooyk Y; Figdor C G
Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses.
Cell 2000;100(5):575-85.
2000: Bleijs D A; Binnerts M E; van Vliet S J; Figdor C G; van Kooyk Y
Low-affinity LFA-1/ICAM-3 interactions augment LFA-1/ICAM-1-mediated T cell adhesion and signaling by redistribution of LFA-1.
Journal of cell science 2000;113 ( Pt 3)():391-400.
2000: Fibbe W E; Pruijt J F; van Kooyk Y; Figdor C G; Opdenakker G; Willemze R
The role of metalloproteinases and adhesion molecules in interleukin-8-induced stem-cell mobilization.
Seminars in hematology 2000;37(1 Suppl 2):19-24.
1999: van Kooyk Y; van Vliet S J; Figdor C G
The actin cytoskeleton regulates LFA-1 ligand binding through avidity rather than affinity changes.
The Journal of biological chemistry 1999;274(38):26869-77.
1999: Bleijs D A; de Waal-Malefyt R; Figdor C G; van Kooyk Y
Co-stimulation of T cells results in distinct IL-10 and TNF-alpha cytokine profiles dependent on binding to ICAM-1, ICAM-2 or ICAM-3.
European journal of immunology 1999;29(7):2248-58.
1999: Peters I M; van Kooyk Y; van Vliet S J; de Grooth B G; Figdor C G; Greve J
3D single-particle tracking and optical trap measurements on adhesion proteins.
Cytometry 1999;36(3):189-94.
1999: Binnerts M E; van Kooyk Y
How LFA-1 binds to different ligands.
Immunology today 1999;20(5):240-5.
1999: Fibbe W E; Pruijt J F; Velders G A; Opdenakker G; van Kooyk Y; Figdor C G; Willemze R
Biology of IL-8-induced stem cell mobilization.
Annals of the New York Academy of Sciences 1999;872():71-82.
1999: Pruijt J F; van Kooyk Y; Figdor C G; Willemze R; Fibbe W E
Murine hematopoietic progenitor cells with colony-forming or radioprotective capacity lack expression of the beta 2-integrin LFA-1.
Blood 1999;93(1):107-12.
1998: Willemsen O H; Snel M M; van der Werf K O; de Grooth B G; Greve J; Hinterdorfer P; Gruber H J; Schindler H; van Kooyk Y; Figdor C G
Simultaneous height and adhesion imaging of antibody-antigen interactions by atomic force microscopy.
Biophysical journal 1998;75(5):2220-8.
1998: Pruijt J F; van Kooyk Y; Figdor C G; Lindley I J; Willemze R; Fibbe W E
Anti-LFA-1 blocking antibodies prevent mobilization of hematopoietic progenitor cells induced by interleukin-8.
Blood 1998;91(11):4099-105.
1998: Degen W G; van Kempen L C; Gijzen E G; van Groningen J J; van Kooyk Y; Bloemers H P; Swart G W
MEMD, a new cell adhesion molecule in metastasizing human melanoma cell lines, is identical to ALCAM (activated leukocyte cell adhesion molecule).
The American journal of pathology 1998;152(3):805-13.
1998: van Kooyk Y; Lub M; Figdor C G
Adhesion and signaling mediated by the cytoplasmic tails of leucocyte integrins.
Cell adhesion and communication 1998;6(2-3):247-54.
1997: van Kooyk Y; Figdor C G
Signalling and adhesive properties of the integrin leucocyte function-associated antigen 1 (LFA-1).
Biochemical Society transactions 1997;25(2):515-20.
1997: Lub M; van Vliet S J; Oomen S P; Pieters R A; Robinson M; Figdor C G; van Kooyk Y
Cytoplasmic tails of beta 1, beta 2, and beta 7 integrins differentially regulate LFA-1 function in K562 cells.
Molecular biology of the cell 1997;8(4):719-28.
1997: Lub M; van Kooyk Y; van Vliet S J; Figdor C G
Dual role of the actin cytoskeleton in regulating cell adhesion mediated by the integrin lymphocyte function-associated molecule-1.
Molecular biology of the cell 1997;8(2):341-51.
1996: Lub M; van Kooyk Y; Figdor C G
Competition between lymphocyte function-associated antigen 1 (CD11a/CD18) and Mac-1 (CD11b/CD18) for binding to intercellular adhesion molecule-1 (CD54).
Journal of leukocyte biology 1996;59(5):648-55.
1996: Torensma R; Raymakers R A; van Kooyk Y; Figdor C G
Induction of LFA-1 on pluripotent CD34+ bone marrow cells does not affect lineage commitment.
Blood 1996;87(10):4120-8.
1996: Binnerts M E; van Kooyk Y; Edwards C P; Champe M; Presta L; Bodary S C; Figdor C G; Berman P W
Antibodies that selectively inhibit leukocyte function-associated antigen 1 binding to intercellular adhesion molecule-3 recognize a unique epitope within the CD11a I domain.
The Journal of biological chemistry 1996;271(17):9962-8.
1996: van Kooyk Y; Binnerts M E; Edwards C P; Champe M; Berman P W; Figdor C G; Bodary S C
Critical amino acids in the lymphocyte function-associated antigen-1 I domain mediate intercellular adhesion molecule 3 binding and immune function.
The Journal of experimental medicine 1996;183(3):1247-52.
1995: Lub M; van Kooyk Y; Figdor C G
Ins and outs of LFA-1.
Immunology today 1995;16(10):479-83.
1994: Binnerts M E; van Kooyk Y; Simmons D L; Figdor C G
Distinct binding of T lymphocytes to ICAM-1, -2 or -3 upon activation of LFA-1.
European journal of immunology 1994;24(9):2155-60.
1994: van Kooyk Y; de Vries-van der Zwan A; de Waal L P; Figdor C G
Efficiency of antibodies directed against adhesion molecules to prolong skin graft survival in mice.
Transplantation proceedings 1994;26(2):401-3.
1994: van Kooyk Y; Weder P; Heije K; Figdor C G
Extracellular Ca2+ modulates leukocyte function-associated antigen-1 cell surface distribution on T lymphocytes and consequently affects cell adhesion.
The Journal of cell biology 1994;124(6):1061-70.
1993: Vyth-Dreese F A; Dellemijn T A; Frijhoff A; van Kooyk Y; Figdor C G
Role of LFA-1/ICAM-1 in interleukin-2-stimulated lymphocyte proliferation.
European journal of immunology 1993;23(12):3292-9.
1993: van Kooyk Y; Figdor C G
Lymphocyte adhesion mediated by integrins.
Research in immunology 1993;144(9):709-22; discussion 754-62.
1993: van Kooyk Y; Weder P; Heije K; de Waal Malefijt R; Figdor C G
Role of intracellular Ca2+ levels in the regulation of CD11a/CD18 mediated cell adhesion.
Cell adhesion and communication 1993;1(1):21-32.
1993: Vyth-Dreese F A; Van Kooyk Y; Dellemijn T A; Melief C J; Figdor C G
Regulatory effect of interleukin-4 (IL-4) on the expression and function of lymphocyte adhesion receptors involved in IL-2-induced cell aggregation.
Immunology 1993;78(2):244-51.
1993: van Kooyk Y; van de Wiel-van Kemenade E; Weder P; Huijbens R J; Figdor C G
Lymphocyte function-associated antigen 1 dominates very late antigen 4 in binding of activated T cells to endothelium.
The Journal of experimental medicine 1993;177(1):185-90.
1993: van Kooyk Y; Figdor C G
Activation and inactivation of adhesion molecules.
Current topics in microbiology and immunology 1993;184():235-56.
1992: van de Wiel-van Kemenade E; van Kooyk Y; de Boer A J; Huijbens R J; Weder P; van de Kasteele W; Melief C J; Figdor C G
Adhesion of T and B lymphocytes to extracellular matrix and endothelial cells can be regulated through the beta subunit of VLA.
The Journal of cell biology 1992;117(2):461-70.
1991: van Kooyk Y; Weder P; Hogervorst F; Verhoeven A J; van Seventer G; te Velde A A; Borst J; Keizer G D; Figdor C G
Activation of LFA-1 through a Ca2(+)-dependent epitope stimulates lymphocyte adhesion.
The Journal of cell biology 1991;112(2):345-54.
1990: Figdor C G; van Kooyk Y; Keizer G D
On the mode of action of LFA-1.
Immunology today 1990;11(8):277-80.
1989: van Kooyk Y; van de Wiel-van Kemenade P; Weder P; Kuijpers T W; Figdor C G
Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes.
Nature 1989;342(6251):811-3.

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