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Koen Van Laere

Research Profile

Chemicals & Drugs

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Anatomy

Brain

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Image Processing, Computer-Assisted

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Physiology

Cerebrovascular Circulation

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Parkinson's Disease

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Publications

TOP 3
Daisy van Veghel; Alfons Verbruggen; Peter M Blumberg; Jan Cleynhens; Ian A Deandrea-Lazarus; Larry V Pearce; Koen Van Laere; Guy Bormans
New transient receptor potential vanilloid subfamily member 1 positron emission tomography radioligands: synthesis, radiolabeling, and preclinical evaluation.
Shana Wauters; Geert M Verleden; Peter Vermaelen; Michel Koole; Jana Somers; Koen Van Laere; Johannes van Loon; Dirk Van Raemdonck
Fluoro-D-glucose-micro positron emission tomography as a diagnostic tool to confirm brain death in a murine donor lung injury model.
Esther Wolfs; Guy Bormans; Olivier Gheysens; Ivo Lambrichts; Frank P Luyten; Tineke Notelaers; Scott J Roberts; Abhishek Sohni; Tom Struys; Koen Van Laere; Catherine M Verfaillie; Christophe M Deroose
18F-FDG labeling of mesenchymal stem cells and multipotent adult progenitor cells for PET imaging: effects on ultrastructure and differentiation capacity.

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All Publications

2013: Daisy van Veghel; Alfons Verbruggen; Peter M Blumberg; Jan Cleynhens; Ian A Deandrea-Lazarus; Larry V Pearce; Koen Van Laere; Guy Bormans
New transient receptor potential vanilloid subfamily member 1 positron emission tomography radioligands: synthesis, radiolabeling, and preclinical evaluation.
ACS chemical neuroscience 2013;4(4):624-34.
2013: Shana Wauters; Geert M Verleden; Peter Vermaelen; Michel Koole; Jana Somers; Koen Van Laere; Johannes van Loon; Dirk Van Raemdonck
Fluoro-D-glucose-micro positron emission tomography as a diagnostic tool to confirm brain death in a murine donor lung injury model.
The Journal of surgical research 2013;180(2):343-8.
2013: Esther Wolfs; Guy Bormans; Olivier Gheysens; Ivo Lambrichts; Frank P Luyten; Tineke Notelaers; Scott J Roberts; Abhishek Sohni; Tom Struys; Koen Van Laere; Catherine M Verfaillie; Christophe M Deroose
18F-FDG labeling of mesenchymal stem cells and multipotent adult progenitor cells for PET imaging: effects on ultrastructure and differentiation capacity.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2013;54(3):447-54.
2013: Eric D Hostetler; Aniket D Joshi; Hiroshi Kawamoto; Stephen M Krause; Hisashi Ohta; Osamu Okamoto; Stacey O'Malley; Satoshi Ozaki; Shailendra Patel; Tom Reynders; Kerry Riffel; Christine Ryan; Sandra Sanabria; Koen Van Laere; Sheng Bi; Guy Bormans; H Donald Burns; William Cho; Jacquelynn J Cook; Tjibbe de Groot; Jan de Hoon; Inge De Lepeleire; M Depré; Michael Egan; Waisi Eng; Raymond E Gibson; Richard J Hargreaves
Evaluation of [¹⁸F]MK-0911, a positron emission tomography (PET) tracer for opioid receptor-like 1 (ORL1), in rhesus monkey and human.
NeuroImage 2013;68():1-10.
2013: Elske Vrieze; Guy Bormans; Jenny Ceccarini; Koen Demyttenaere; Diego A Pizzagalli; Koen Van Laere; Mathieu Vandenbulcke; Stephan Claes
Measuring extrastriatal dopamine release during a reward learning task.
Human brain mapping 2013;34(3):575-86.
2013: Koen Van Laere; Mark E Schmidt; Rawaha U Ahmad; Guy Bormans; Sofie Celen; Kristof Dubois; Hendra Hudyana; Michel Koole
Human biodistribution and dosimetry of 18F-JNJ42259152, a radioligand for phosphodiesterase 10A imaging.
European journal of nuclear medicine and molecular imaging 2013;40(2):254-61.
2013: Daisy van Veghel; Alfons Verbruggen; Peter M Blumberg; Jan Cleynhens; Larry V Pearce; Koen Van Laere; Guy Bormans
Synthesis and biological evaluation of [¹¹C]SB366791: a new PET-radioligand for in vivo imaging of the TRPV1 receptor.
Nuclear medicine and biology 2013;40(1):141-7.
2013: Rik Vandenberghe; Allan Andersen; David J Brooks; Steen Hasselbalch; Adrian Ivanoiu; Alex Korner; Lennart Minthon; Natalie Nelissen; Eric Salmon; Koen Van Laere; Patrick Dupont
Binary classification of ¹⁸F-flutemetamol PET using machine learning: comparison with visual reads and structural MRI.
NeuroImage 2013;64():517-25.
2013: Agneta Nordberg; Aren Okello; Daniela Perani; Juha Rinne; Noora Scheinin; Koen Van Laere; Rik Vandenberghe; Mathieu Vandenbulcke; Ove Almkvist; David J Brooks; Stephen F Carter; Alexander Drzezga; Paul Edison; Anton Forsberg; Valentina Garibotto; Timo Grimmer; Rainer Hinz; Elke Kalbe; Mira Karrasch; Bengt Långström; Isabelle Miederer; Kjell Någren; Natalie Nelissen; Karl Herholz
A European multicentre PET study of fibrillar amyloid in Alzheimer's disease.
European journal of nuclear medicine and molecular imaging 2013;40(1):104-14.
2012: Caroline Vandeputte; Daisy van Veghel; Guy Bormans; Cindy Casteels; Tom Dresselaers; Nele Evens; Anneleen Gerits; Uwe Himmelreich; Michel Koole; Ivo Lambrichts; Tom Struys; Koen Van Laere
Small-animal PET imaging of the type 1 and type 2 cannabinoid receptors in a photothrombotic stroke model.
European journal of nuclear medicine and molecular imaging 2012;39(11):1796-806.
2012: Jenny Ceccarini; Stephan Claes; Michel Koole; Tom Muylle; Guy Bormans; Elske Vrieze; Koen Van Laere
Optimized in vivo detection of dopamine release using 18F-fallypride PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2012;53(10):1565-72.
2012: Cindy Casteels; Sofie Celen; Michel Koole; Guy Bormans; Koen Van Laere
Preclinical evaluation and quantification of [¹⁸F]MK-9470 as a radioligand for PET imaging of the type 1 cannabinoid receptor in rat brain.
European journal of nuclear medicine and molecular imaging 2012;39(9):1467-77.
2012: Jan Van den Stock; Koen Van Laere; Beatrice de Gelder; François-Laurent De Winter; Mathieu Vandenbulcke
A strange face in the mirror. Face-selective self-misidentification in a patient with right lateralized occipito-temporal hypo-metabolism.
Cortex; a journal devoted to the study of the nervous system and behavior 2012;48(8):1088-90.
2012: Nele Evens; Peter Janssen; Raf Sciot; Koen Van Laere; Caroline Vandeputte; Alfons M Verbruggen; Veerle Baekelandt; Charlotte Coolen; zeger debyser; Guy M Bormans
Preclinical evaluation of [11C]NE40, a type 2 cannabinoid receptor PET tracer.
Nuclear medicine and biology 2012;39(3):389-99.
2012: Kathleen Vunckx; Anthonin Reilhac; Koen Van Laere; Ameya Atre; Kristof Baete; Christophe M Deroose; Johan Nuyts
Evaluation of three MRI-based anatomical priors for quantitative PET brain imaging.
IEEE transactions on medical imaging 2012;31(3):599-612.
2012: Koen Van Laere; Guy Bormans; Cindy Casteels; Karolien Goffin; Igor D Grachev; Sophie Lunskens; Wim Vandenberghe
Regional changes in type 1 cannabinoid receptor availability in Parkinson's disease in vivo.
Neurobiology of aging 2012;33(3):620.e1-8.
2011: Nicola Trotta; Patrick Van Bogaert; Koen Van Laere; Kristof Baete; Serge Goldman; Nathalie Guerry; Benjamin Legros; Noémie Ligot; Xavier De Tiège
Metabolic evidence for episodic memory plasticity in the nonepileptic temporal lobe of patients with mesial temporal epilepsy.
Epilepsia 2011;52(11):2003-12.
2011: Philippe Demaerel; Wim Van Dessel; Koen Van Laere; Wim Van Paesschen; Rik Vandenberghe; Jennifer Linn
Autoimmune-mediated encephalitis.
Neuroradiology 2011;53(11):837-51.
2011: Nathalie Gérard; Karolien Goffin; Guido Pieters; Guy Bormans; Koen Van Laere
Brain type 1 cannabinoid receptor availability in patients with anorexia and bulimia nervosa.
Biological psychiatry 2011;70(8):777-84.
2011: Johan Barbier; Loes Gabriëls; Koen Van Laere; Bart Nuttin
Successful anterior capsulotomy in comorbid anorexia nervosa and obsessive-compulsive disorder: case report.
Neurosurgery 2011;69(3):E745-51; discussion E751.
2011: Nele Evens; Didier M Lambert; Giulio G Muccioli; Koen Van Laere; Caroline Vandeputte; Alfons M Verbruggen; Veerle Baekelandt; zeger debyser; Guy M Bormans
Synthesis, in vitro and in vivo evaluation of fluorine-18 labelled FE-GW405833 as a PET tracer for type 2 cannabinoid receptor imaging.
Bioorganic & medicinal chemistry 2011;19(15):4499-505.
2011: Caroline Vandeputte; Catherine Verfaillie; Debby Thomas; Koen Van Laere; Veerle Baekelandt; Annelies Crabbe; Tom Dresselaers; Uwe Himmelreich
Characterization of the inflammatory response in a photothrombotic stroke model by MRI: implications for stem cell transplantation.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2011;13(4):663-71.
2011: Caroline Vandeputte; Alfons Verbruggen; Veerle Baekelandt; Guy Bormans; Barbara Bosier; zeger debyser; Christophe M Deroose; Nele Evens; Rik Gijsbers; Abdelilah Ibrahimi; Peter Janssen; Didier M Lambert; Jaan Toelen; Anke Van der Perren; Koen Van Laere
A PET brain reporter gene system based on type 2 cannabinoid receptors.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011;52(7):1102-9.
2011: Cindy Casteels; C Vandeputte; J R Rangarajan; T Dresselaers; O Riess; Guy Bormans; F Maes; U Himmelreich; H Nguyen; Koen Van Laere
Metabolic and type 1 cannabinoid receptor imaging of a transgenic rat model in the early phase of Huntington disease.
Experimental neurology 2011;229(2):440-9.
2011: Lujia Zhou; Nathalie Brouwers; Iryna Benilova; Annelies Vandersteen; Marc Mercken; Koen Van Laere; Philip Van Damme; David Demedts; Fred Van Leuven; Kristel Sleegers; Kerensa Broersen; Christine Van Broeckhoven; Rik Vandenberghe; Bart De Strooper
Amyloid precursor protein mutation E682K at the alternative β-secretase cleavage β'-site increases Aβ generation.
EMBO molecular medicine 2011;3(5):291-302.
2011: Karolien Goffin; Wim Van Paesschen; Koen Van Laere
In vivo activation of endocannabinoid system in temporal lobe epilepsy with hippocampal sclerosis.
Brain : a journal of neurology 2011;134(Pt 4):1033-40.
2010: Cindy Casteels; Emili Martinez; Guy Bormans; Lluïsa Camon; Núria de Vera; Veerle Baekelandt; Anna M Planas; Koen Van Laere
Type 1 cannabinoid receptor mapping with [18F]MK-9470 PET in the rat brain after quinolinic acid lesion: a comparison to dopamine receptors and glucose metabolism.
European journal of nuclear medicine and molecular imaging 2010;37(12):2354-63.
2010: Sofie Celen; Michel Koole; Meri De Angelis; Ivan Sannen; Satish K Chitneni; Jesus Alcazar; Stefanie Dedeurwaerdere; Dieder Moechars; Mark Schmidt; Alfons Verbruggen; Xavier Langlois; Koen Van Laere; José Ignacio Andrés; Guy Bormans
Preclinical evaluation of 18F-JNJ41510417 as a radioligand for PET imaging of phosphodiesterase-10A in the brain.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(10):1584-91.
2010: Nathalie Gérard; Jenny Ceccarini; Guy Bormans; Bert Vanbilloen; Cindy Casteels; Karolien Goffin; Barbara Bosier; Didier M Lambert; Koen Van Laere
Influence of chronic nicotine administration on cerebral type 1 cannabinoid receptor binding: an in vivo micro-PET study in the rat using [18F]MK-9470.
Journal of molecular neuroscience : MN 2010;42(2):162-7.
2010: Koen Van Laere; Cindy Casteels; Isabel Dhollander; Karolien Goffin; Igor Grachev; Guy Bormans; Wim Vandenberghe
Widespread decrease of type 1 cannabinoid receptor availability in Huntington disease in vivo.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(9):1413-7.
2010: Rik Vandenberghe; Koen Van Laere; Adrian Ivanoiu; Eric Salmon; Christine Bastin; Eric Triau; Steen Hasselbalch; Ian Law; Allan Andersen; Alex Korner; Lennart Minthon; Gaëtan Garraux; Natalie Nelissen; Guy Bormans; Chris Buckley; Rikard Owenius; Lennart Thurfjell; Gill Farrar; David J Brooks
18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: a phase 2 trial.
Annals of neurology 2010;68(3):319-29.
2010: Sandra Sanabria; Koen Van Laere
Quantitative PET imaging of radioligands with slow kinetics in human brain.
European journal of nuclear medicine and molecular imaging 2010;37(8):1613-5.
2010: Cindy Casteels; Bert Vanbilloen; Dorien Vercammen; Barbara Bosier; Didier M Lambert; Guy Bormans; Koen Van Laere
Influence of chronic bromocriptine and levodopa administration on cerebral type 1 cannabinoid receptor binding.
Synapse (New York, N.Y.) 2010;64(8):617-23.
2010: Karolien Goffin; Wim Van Paesschen; Patrick Dupont; Kristof Baete; André Palmini; Johan Nuyts; Koen Van Laere
Anatomy-based reconstruction of FDG-PET images with implicit partial volume correction improves detection of hypometabolic regions in patients with epilepsy due to focal cortical dysplasia diagnosed on MRI.
European journal of nuclear medicine and molecular imaging 2010;37(6):1148-55.
2010: Cindy Casteels; Guy Bormans; Koen Van Laere
The effect of anaesthesia on [(18)F]MK-9470 binding to the type 1 cannabinoid receptor in the rat brain.
European journal of nuclear medicine and molecular imaging 2010;37(6):1164-73.
2010: Sandra Sanabria; Terence G Hamill; Karolien Goffin; Inge De Lepeleire; Guy Bormans; H Donald Burns; Koen Van Laere
Kinetic analysis of the cannabinoid-1 receptor PET tracer [(18)F]MK-9470 in human brain.
European journal of nuclear medicine and molecular imaging 2010;37(5):920-33.
2010: Koen Van Laere; Kristien Clerinx; Eduard D'Hondt; Tjibbe de Groot; Wim Vandenberghe
Combined striatal binding and cerebral influx analysis of dynamic 11C-raclopride PET improves early differentiation between multiple-system atrophy and Parkinson disease.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(4):588-95.
2010: Cindy Casteels; Erwin Lauwers; Abdelbari Baitar; Guy Bormans; Veerle Baekelandt; Koen Van Laere
In vivo type 1 cannabinoid receptor mapping in the 6-hydroxydopamine lesion rat model of Parkinson's disease.
Brain research 2010;1316():153-62.
2010: Koen Van Laere; Andrea Varrone; Jan Booij; Thierry Vander Borght; Flavio Nobili; Ozlem L Kapucu; Zuzana Walker; Kjell Någren; Klaus Tatsch; Jacques Darcourt
EANM procedure guidelines for brain neurotransmission SPECT/PET using dopamine D2 receptor ligands, version 2.
European journal of nuclear medicine and molecular imaging 2010;37(2):434-42.
2010: Jacques Darcourt; Jan Booij; Klaus Tatsch; Andrea Varrone; Thierry Vander Borght; Ozlem L Kapucu; Kjell Någren; Flavio Nobili; Zuzana Walker; Koen Van Laere
EANM procedure guidelines for brain neurotransmission SPECT using (123)I-labelled dopamine transporter ligands, version 2.
European journal of nuclear medicine and molecular imaging 2010;37(2):443-50.
2010: Caroline Vandeputte; Jean-Marc Taymans; Cindy Casteels; Frea Coun; Yicheng Ni; Koen Van Laere; Veerle Baekelandt
Automated quantitative gait analysis in animal models of movement disorders.
BMC neuroscience 2010;11():92.
2010: Annelies Crabbe; Caroline Vandeputte; Tom Dresselaers; Angel Ayuso Sacido; Jose Manuel Garcia Verdugo; Jeroen Eyckmans; Frank P Luyten; Koen Van Laere; Catherine M Verfaillie; Uwe Himmelreich
Effects of MRI contrast agents on the stem cell phenotype.
Cell transplantation 2010;19(8):919-36.
2009: Andrea Varrone; Susanne Asenbaum; Thierry Vander Borght; Jan Booij; Flavio Nobili; Kjell Någren; Jacques Darcourt; Ozlem L Kapucu; Klaus Tatsch; Peter Bartenstein; Koen Van Laere
EANM procedure guidelines for PET brain imaging using [18F]FDG, version 2.
European journal of nuclear medicine and molecular imaging 2009;36(12):2103-10.
2009: Ozlem L Kapucu; Flavio Nobili; Andrea Varrone; Jan Booij; Thierry Vander Borght; Kjell Någren; Jacques Darcourt; Klaus Tatsch; Koen Van Laere
EANM procedure guideline for brain perfusion SPECT using 99mTc-labelled radiopharmaceuticals, version 2.
European journal of nuclear medicine and molecular imaging 2009;36(12):2093-102.
2009: Kim Serdons; Koen Van Laere; Peter Janssen; Hank F Kung; Guy Bormans; Alfons Verbruggen
Synthesis and evaluation of three 18F-labeled aminophenylbenzothiazoles as amyloid imaging agents.
Journal of medicinal chemistry 2009;52(22):7090-102.
2009: Kris van Kuyck; Nathalie Gérard; Koen Van Laere; Cindy Casteels; Guido Pieters; Loes Gabriëls; Bart Nuttin
Towards a neurocircuitry in anorexia nervosa: evidence from functional neuroimaging studies.
Journal of psychiatric research 2009;43(14):1133-45.
2009: Natalie Nelissen; Koen Van Laere; Lennart Thurfjell; Rikard Owenius; Mathieu Vandenbulcke; Michel Koole; Guy Bormans; David J Brooks; Rik Vandenberghe
Phase 1 study of the Pittsburgh compound B derivative 18F-flutemetamol in healthy volunteers and patients with probable Alzheimer disease.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(8):1251-9.
2009: Hans Hallez; M De Vos; Bart Vanrumste; Peter Van Hese; Sara Assecondi; Koen Van Laere; P Dupont; W Van Paesschen; Sabine Van Huffel; Ignace Lemahieu
Removing muscle and eye artifacts using blind source separation techniques in ictal EEG source imaging.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2009;120(7):1262-72.
2009: Nele Evens; Giulio G Muccioli; Nele Houbrechts; Didier M Lambert; Alfons M Verbruggen; Koen Van Laere; Guy M Bormans
Synthesis and biological evaluation of carbon-11- and fluorine-18-labeled 2-oxoquinoline derivatives for type 2 cannabinoid receptor positron emission tomography imaging.
Nuclear medicine and biology 2009;36(4):455-65.
2009: Kim Serdons; Christelle Terwinghe; Peter Vermaelen; Koen Van Laere; Hank Kung; Luc Mortelmans; Guy Bormans; Alfons Verbruggen
Synthesis and evaluation of 18F-labeled 2-phenylbenzothiazoles as positron emission tomography imaging agents for amyloid plaques in Alzheimer's disease.
Journal of medicinal chemistry 2009;52(5):1428-37.
2009: Koen Van Laere; Karolien Goffin; Guy Bormans; Cindy Casteels; Luc Mortelmans; Jan de Hoon; Igor Grachev; Mathieu Vandenbulcke; Guido Pieters
Relationship of type 1 cannabinoid receptor availability in the human brain to novelty-seeking temperament.
Archives of general psychiatry 2009;66(2):196-204.
2009: Wim Vandenberghe; Koen Van Laere; Frederik Debruyne; Christine Van Broeckhoven; Gert Van Goethem
Neurodegenerative Parkinsonism and progressive external ophthalmoplegia with a Twinkle mutation.
Movement disorders : official journal of the Movement Disorder Society 2009;24(2):308-9.
2009: L Zhou; Patrick Dupont; Kristof Baete; Wim Van Paesschen; Koen Van Laere; Johan Nuyts
Detection of inter-hemispheric metabolic asymmetries in FDG-PET images using prior anatomical information.
NeuroImage 2009;44(1):35-42.
2008: Kristl Vonck; Veerle De Herdt; Tommy Bosman; Stefanie Dedeurwaerdere; Koen Van Laere; Paul Boon
Thalamic and limbic involvement in the mechanism of action of vagus nerve stimulation, a SPECT study.
Seizure : the journal of the British Epilepsy Association 2008;17(8):699-706.
2008: Koen Van Laere; Guy Bormans; Sandra Sanabria; Tjibbe de Groot; Patrick Dupont; Inge De Lepeleire; Jan de Hoon; Luc Mortelmans; Richard Hargreaves; John R Atack; H Donald Burns
In vivo characterization and dynamic receptor occupancy imaging of TPA023B, an alpha 2/alpha 3/alpha 5 subtype selective gamma-aminobutyric acid-a partial agonist.
Biological psychiatry 2008;64(2):153-61.
2008: Karolien Goffin; Stefanie Dedeurwaerdere; Koen Van Laere; Wim Van Paesschen
Neuronuclear assessment of patients with epilepsy.
Seminars in nuclear medicine 2008;38(4):227-39.
2008: Koen Van Laere; Ludwig Everaert; Lieven Annemans; Michel Gonce; Wim Vandenberghe; Thierry Vander Borght
The cost effectiveness of 123I-FP-CIT SPECT imaging in patients with an uncertain clinical diagnosis of parkinsonism.
European journal of nuclear medicine and molecular imaging 2008;35(7):1367-76.
2008: Koen Van Laere; Michel Koole; Sandra M Sanabria Bohorquez; Karolien Goffin; Ilonka Guenther; Marie J Belanger; Josee Cote; Paul Rothenberg; Inge De Lepeleire; Igor D Grachev; Richard J Hargreaves; Guy Bormans; H Donald Burns
Whole-body biodistribution and radiation dosimetry of the human cannabinoid type-1 receptor ligand 18F-MK-9470 in healthy subjects.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(3):439-45.
2008: Koen Van Laere; Karolien Goffin; Cindy Casteels; Patrick Dupont; Luc Mortelmans; Jan de Hoon; Guy Bormans
Gender-dependent increases with healthy aging of the human cerebral cannabinoid-type 1 receptor binding using [(18)F]MK-9470 PET.
NeuroImage 2008;39(4):1533-41.
2008: Satish K Chitneni; Lucette Garreau; Bernard J Cleynhens; Nele Evens; Marva Bex; Peter Vermaelen; Sylvie Chalon; Roger Busson; Denis Guilloteau; Koen Van Laere; Alfons Verbruggen; Guy Bormans
Improved synthesis and metabolic stability analysis of the dopamine transporter ligand [(18)F]FECT.
Nuclear medicine and biology 2008;35(1):75-82.
2008: Cindy Casteels; Erwin Lauwers; Guy Bormans; Veerle Baekelandt; Koen Van Laere
Metabolic-dopaminergic mapping of the 6-hydroxydopamine rat model for Parkinson's disease.
European journal of nuclear medicine and molecular imaging 2008;35(1):124-34.
2007: Gérard Moulin-Romsée; Eduard D'Hondt; Tjibbe de Groot; Jan Goffin; Raf Sciot; Luc Mortelmans; Johan J Menten; Guy Bormans; Koen Van Laere
Non-invasive grading of brain tumours using dynamic amino acid PET imaging: does it work for 11C-methionine?
European journal of nuclear medicine and molecular imaging 2007;34(12):2082-7.
2007: Koen Van Laere
In vivo imaging of the endocannabinoid system: a novel window to a central modulatory mechanism in humans.
European journal of nuclear medicine and molecular imaging 2007;34(11):1719-26.
2007: Wim Van Paesschen; Kathleen Porke; Katrien Fannes; Rik Vandenberghe; André Palmini; Koen Van Laere; Patrick Dupont
Cognitive deficits during status epilepticus and time course of recovery: a case report.
Epilepsia 2007;48(10):1979-83.
2007: Wim Vandenberghe; Raf Sciot; Philippe Demaerel; Koen Van Laere
Sparing of the substantia nigra in sporadic Creutzfeldt-Jakob disease presenting as an acute corticobasal syndrome.
Movement disorders : official journal of the Movement Disorder Society 2007;22(11):1668-9.
2007: Natalie Nelissen; Mathieu Vandenbulcke; Katrien Fannes; Alfons Verbruggen; Ronald Peeters; Patrick Dupont; Koen Van Laere; Guy Bormans; Rik Vandenberghe
Abeta amyloid deposition in the language system and how the brain responds.
Brain : a journal of neurology 2007;130(Pt 8):2055-69.
2007: Karolien Goffin; Jari Nissinen; Koen Van Laere; Asla Pitkänen
Cyclicity of spontaneous recurrent seizures in pilocarpine model of temporal lobe epilepsy in rat.
Experimental neurology 2007;205(2):501-5.
2007: Wim Van Paesschen; Patrick Dupont; Stefan Sunaert; Karolien Goffin; Koen Van Laere
The use of SPECT and PET in routine clinical practice in epilepsy.
Current opinion in neurology 2007;20(2):194-202.
2007: Kris van Kuyck; Cindy Casteels; Peter Vermaelen; Guy Bormans; Bart Nuttin; Koen Van Laere
Motor- and food-related metabolic cerebral changes in the activity-based rat model for anorexia nervosa: a voxel-based microPET study.
NeuroImage 2007;35(1):214-21.
2007: Erwin Lauwers; Dirk Bequé; Koen Van Laere; Johan Nuyts; Guy Bormans; Luc Mortelmans; Cindy Casteels; Linda Vercammen; Olivier Bockstael; Bart Nuttin; zeger debyser; Veerle Baekelandt
Non-invasive imaging of neuropathology in a rat model of alpha-synuclein overexpression.
Neurobiology of aging 2007;28(2):248-57.
2006: Cindy Casteels; Peter Vermaelen; Johan Nuyts; Annemie Van Der Linden; Veerle Baekelandt; Luc Mortelmans; Guy Bormans; Koen Van Laere
Construction and evaluation of multitracer small-animal PET probabilistic atlases for voxel-based functional mapping of the rat brain.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(11):1858-66.
2006: Patrick Dupont; Wim Van Paesschen; André Palmini; Rudo Ambayi; Johannes van Loon; Jan Goffin; Sarah Weckhuysen; Stefan Sunaert; Bejoy Thomas; Philippe Demaerel; Raf Sciot; Albert J Becker; Hubert P Vanbilloen; Luc Mortelmans; Koen Van Laere
Ictal perfusion patterns associated with single MRI-visible focal dysplastic lesions: implications for the noninvasive delineation of the epileptogenic zone.
Epilepsia 2006;47(9):1550-7.
2006: N Nelissen; Wim Van Paesschen; Kristof Baete; Koen Van Laere; André Palmini; H Van Billoen; Patrick Dupont
Correlations of interictal FDG-PET metabolism and ictal SPECT perfusion changes in human temporal lobe epilepsy with hippocampal sclerosis.
NeuroImage 2006;32(2):684-95.
2006: Sarah Ceyssens; Koen Van Laere; Tjibbe de Groot; Jan Goffin; Guy Bormans; Luc Mortelmans
[11C]methionine PET, histopathology, and survival in primary brain tumors and recurrence.
AJNR. American journal of neuroradiology 2006;27(7):1432-7.
2006: Stefanie Dedeurwaerdere; Kristl Vonck; Veerle De Herdt; Liesbeth Waterschoot; Tim De Smedt; Robrecht Raedt; Tine Wyckhuys; Benjamin Legros; Peter Van Hese; Koen Van Laere; Jean Delbeke; Wytse J Wadman; Paul Boon
Neuromodulation with levetiracetam and vagus nerve stimulation in experimental animal models of epilepsy.
Acta neurologica Belgica 2006;106(2):91-7.
2006: Koen Van Laere; Bart Nuttin; Loes gabriels; Patrick Dupont; Steve Rasmussen; Benjamin D Greenberg; Paul Cosyns
Metabolic imaging of anterior capsular stimulation in refractory obsessive-compulsive disorder: a key role for the subgenual anterior cingulate and ventral striatum.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(5):740-7.
2006: Koen Van Laere; Cindy Casteels; Liesbet De Ceuninck; Bert Vanbilloen; Alex Maes; Luc Mortelmans; Wim Vandenberghe; Alfons Verbruggen; René Dom
Dual-tracer dopamine transporter and perfusion SPECT in differential diagnosis of parkinsonism using template-based discriminant analysis.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(3):384-92.
2005: Stefanie Dedeurwaerdere; Bart Cornelissen; Koen Van Laere; Kristl Vonck; Eric Achten; Guido Slegers; Paul Boon
Small animal positron emission tomography during vagus nerve stimulation in rats: a pilot study.
Epilepsy research 2005;67(3):133-41.
2005: G Moulin-Romsee; A Maes; D Silverman; L Mortelmans; Koen Van Laere
Cost-effectiveness of 18F-fluorodeoxyglucose positron emission tomography in the assessment of early dementia from a Belgian and European perspective.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2005;12(4):254-63.
2005: Koen Van Laere; Sarah Ceyssens; Frank Van Calenbergh; Tjibbe de Groot; Johan J Menten; Patrick Flamen; Guy Bormans; Luc Mortelmans
Direct comparison of 18F-FDG and 11C-methionine PET in suspected recurrence of glioma: sensitivity, inter-observer variability and prognostic value.
European journal of nuclear medicine and molecular imaging 2005;32(1):39-51.
2004: Kristof Baete; Johan Nuyts; Koen Van Laere; Wim Van Paesschen; Sarah Ceyssens; Liesbet De Ceuninck; Olivier Gheysens; Annemarie Kelles; Jimmy Van den Eynden; Paul Suetens; Patrick Dupont
Evaluation of anatomy based reconstruction for partial volume correction in brain FDG-PET.
NeuroImage 2004;23(1):305-17.
2004: Koen Van Laere; Liesbet De Ceuninck; René Dom; J Van den Eynden; Hubert P Vanbilloen; J Cleynhens; Patrick Dupont; Guy Bormans; Alfons Verbruggen; Luc Mortelmans
Dopamine transporter SPECT using fast kinetic ligands: 123I-FP-beta-CIT versus 99mTc-TRODAT-1.
European journal of nuclear medicine and molecular imaging 2004;31(8):1119-27.
2004: Koen Van Laere; Patrick Santens; Tommy Bosman; Jacques de Reuck; Luc Mortelmans; Rudi Dierckx
Statistical parametric mapping of (99m)Tc-ECD SPECT in idiopathic Parkinson's disease and multiple system atrophy with predominant parkinsonian features: correlation with clinical parameters.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(6):933-42.
2004: Filip Gemmel; Frederic De Winter; Koen Van Laere; Dirk Vogelaers; Dirk Uyttendaele; Rudi A Dierckx
99mTc ciprofloxacin imaging for the diagnosis of infection in the postoperative spine.
Nuclear medicine communications 2004;25(3):277-83.
2004: Frederic De Winter; Filip Gemmel; Koen Van Laere; Olivier De Winter; Bart Poffijn; Rudi A Dierckx; Christophe Van De Wiele
99mTc-ciprofloxacin planar and tomographic imaging for the diagnosis of infection in the postoperative spine: experience in 48 patients.
European journal of nuclear medicine and molecular imaging 2004;31(2):233-9.
2003: Kristl Vonck; Paul Boon; Lut Goossens; Stefanie Dedeurwaerdere; Pieter Claeys; Fleur Gossiaux; Peter Van Hese; Tim De Smedt; Robrecht Raedt; Eric Achten; Karel Deblaere; Ann Thieleman; Pieter Vandemaele; evert thiery; Guy Vingerhoets; Marijke Miatton; Jacques Caemaert; Dirk Van Roost; Edward Baert; Geert Michielsen; Frank Dewaele; Koen Van Laere; Vijay Thadani; Dave Robertson; Peter Williamson
Neurostimulation for refractory epilepsy.
Acta neurologica Belgica 2003;103(4):213-7.
2003: Jan Versijpt; Koen Van Laere; Filip Dumont; Danny Decoo; Marleen Vandecapelle; Patrick Santens; Ingeborg Goethals; Kurt Audenaert; Guido Slegers; Rudi A Dierckx; Jakob Korf
Imaging of the 5-HT2A system: age-, gender-, and Alzheimer's disease-related findings.
Neurobiology of aging 2003;24(4):553-61.
2003: Jan C Debruyne; Jan Versijpt; Koen Van Laere; Filip De Vos; J Keppens; Karel Strijckmans; Eric Achten; Guido Slegers; Rudi A Dierckx; Jakob Korf; Jacques de Reuck
PET visualization of microglia in multiple sclerosis patients using [11C]PK11195.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2003;10(3):257-64.
2003: Cees Van Heeringen; Kurt Audenaert; Koen Van Laere; Filip Dumont; Guido Slegers; John Mertens; Rudi A Dierckx
Prefrontal 5-HT2a receptor binding index, hopelessness and personality characteristics in attempted suicide.
Journal of affective disorders 2003;74(2):149-58.
2003: Kurt Audenaert; Koen Van Laere; Filip Dumont; Myriam Vervaet; Ingeborg Goethals; Guido Slegers; John Mertens; Cees Van Heeringen; Rudi A Dierckx
Decreased 5-HT2a receptor binding in patients with anorexia nervosa.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2003;44(2):163-9.
2003: Jan Versijpt; Koen Van Laere; Rudi A Dierckx; Filip Dumont; P P De Deyn; Guido Slegers; Jakob Korf
Scintigraphic visualization of inflammation in neurodegenerative disorders.
Nuclear medicine communications 2003;24(2):209-21.
2003: Jan Versijpt; Filip Dumont; Koen Van Laere; Danny Decoo; Patrick Santens; Kurt Audenaert; Eric Achten; Guido Slegers; Rudi A Dierckx; Jakob Korf
Assessment of neuroinflammation and microglial activation in Alzheimer's disease with radiolabelled PK11195 and single photon emission computed tomography. A pilot study.
European neurology 2003;50(1):39-47.
2003: Patrick Santens; T De Corte; Guy Vingerhoets; Koen Van Laere; Rudi Dierckx; Jacques de Reuck
Regional cerebral blood flow and episodic memory in Parkinson's disease: a single photon emission tomography study.
European neurology 2003;49(4):238-42.
2003: Tommy Bosman; Koen Van Laere; Patrick Santens
Anatomically standardised 99mTc-ECD brain perfusion SPET allows accurate differentiation between healthy volunteers, multiple system atrophy and idiopathic Parkinson's disease.
European journal of nuclear medicine and molecular imaging 2003;30(1):16-24.
2002: Jan C Debruyne; Koen Van Laere; Jan Versijpt; Filip De Vos; Johan Keppens Eng; Karel Strijckmans; Patrick Santens; Eric Achten; Guido Slegers; Jakob Korf; Rudi A Dierckx; Jacques de Reuck
Semiquantification of the peripheral-type benzodiazepine ligand [11C]PK11195 in normal human brain and application in multiple sclerosis patients.
Acta neurologica Belgica 2002;102(3):127-35.
2002: Kurt Audenaert; Ingeborg Goethals; Koen Van Laere; Philippe Lahorte; Boudewijn Brans; Jan Versijpt; Myriam Vervaet; L Beelaert; Kees van Heeringen; Rudi Dierckx
SPECT neuropsychological activation procedure with the Verbal Fluency Test in attempted suicide patients.
Nuclear medicine communications 2002;23(9):907-16.
2002: Boudewijn Brans; Koen Van Laere; Filip Gemmel; Luc Defreyne; Peter Vanlangenhove; Roberto Troisi; Hans Van Vlierberghe; Isabelle Colle; Bernard De Hemptinne; Rudi A Dierckx
Combining iodine-131 Lipiodol therapy with low-dose cisplatin as a radiosensitiser: preliminary results in hepatocellular carcinoma.
European journal of nuclear medicine and molecular imaging 2002;29(7):928-32.
2002: Koen Van Laere; Kristl Vonck; Paul Boon; Jan Versijpt; Rudi Dierckx
Perfusion SPECT changes after acute and chronic vagus nerve stimulation in relation to prestimulus condition and long-term clinical efficacy.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2002;43(6):733-44.
2002: Koen Van Laere; Jan Versijpt; Michel Koole; Stefaan Vandenberghe; Philippe Lahorte; Ignace Lemahieu; Rudi A Dierckx
Experimental performance assessment of SPM for SPECT neuroactivation studies using a subresolution sandwich phantom design.
NeuroImage 2002;16(1):200-16.
2002: Koen Van Laere; James Warwick; Jan Versijpt; Ingeborg Goethals; Kurt Audenaert; Ben Van Heerden; Rudi Dierckx
Analysis of clinical brain SPECT data based on anatomic standardization and reference to normal data: an ROC-based comparison of visual, semiquantitative, and voxel-based methods.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2002;43(4):458-69.
2001: Koen Van Laere; Rudi A Dierckx
Brain perfusion SPECT: age- and sex-related effects correlated with voxel-based morphometric findings in healthy adults.
Radiology 2001;221(3):810-7.
2001: Kathelijne Peremans; Pieter De Bondt; Kurt Audenaert; Koen Van Laere; Ingrid M Gielen; Michel Koole; Jan Versijpt; Henri van Bree; Francis Verschooten; Rudi Dierckx
Regional brain perfusion in 10 normal dogs measured using Technetium-99m ethyl cysteinate dimer spect.
Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association 2001;42(6):562-8.
2001: Kristl Vonck; Koen Van Laere; Stefanie Dedeurwaerdere; Jacques Caemaert; Jacques de Reuck; Paul Boon
The mechanism of action of vagus nerve stimulation for refractory epilepsy: the current status.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society 2001;18(5):394-401.
2001: Koen Van Laere; Jan Versijpt; Kurt Audenaert; Michel Koole; Ingeborg Goethals; Eric Achten; Rudi Dierckx
99mTc-ECD brain perfusion SPET: variability, asymmetry and effects of age and gender in healthy adults.
European journal of nuclear medicine 2001;28(7):873-87.
2001: Koen Van Laere; Filip Dumont; Michel Koole; Rudi Dierckx
Non-invasive methods for absolute cerebral blood flow measurement using 99mTc-ECD: a study in healthy volunteers.
European journal of nuclear medicine 2001;28(7):862-72.
2001: Jan Versijpt; Danny Decoo; Koen Van Laere; Eric Achten; Kurt Audenaert; Yves D'Asseler; Guido Slegers; Rudi A Dierckx; Jakob Korf
57Co SPECT, 99mTc-ECD SPECT, MRI and neuropsychological testing in senile dementia of the Alzheimer type.
Nuclear medicine communications 2001;22(6):713-9.
2001: Koen Van Laere; Michel Koole; Jan Versijpt; Stefaan Vandenberghe; Boudewijn Brans; Yves D'Asseler; Olivier De Winter; Alain Kalmar; Rudi Dierckx
Transfer of normal 99mTc-ECD brain SPET databases between different gamma cameras.
European journal of nuclear medicine 2001;28(4):435-49.
2001: Koen Van Laere; Michel Koole; Ignace Lemahieu; Rudi Dierckx
Image filtering in single-photon emission computed tomography: principles and applications.
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society 2001;25(2):127-33.
2001: Stefaan Vandenberghe; Yves D'Asseler; Rik Van de Walle; T Kauppinen; Michel Koole; LR Bouwens; Koen Van Laere; Ignace Lemahieu; Rudi A Dierckx
Iterative reconstruction algorithms in nuclear medicine.
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society 2001;25(2):105-11.
2001: Kurt Audenaert; Koen Van Laere; Filip Dumont; Guido Slegers; John Mertens; Cees Van Heeringen; Rudi A Dierckx
Decreased frontal serotonin 5-HT 2a receptor binding index in deliberate self-harm patients.
European journal of nuclear medicine 2001;28(2):175-82.
2001: Kurt Audenaert; Philippe Lahorte; Boudewijn Brans; Koen Van Laere; Ingeborg Goethals; Kees van Heeringen; Rudi A Dierckx
The classical stroop interference task as a prefrontal activation probe: a validation study using 99Tcm-ECD brain SPECT.
Nuclear medicine communications 2001;22(2):135-43.
2001: Koen Van Laere; Michel Koole; Yves D'Asseler; Jan Versijpt; Kurt Audenaert; Filip Dumont; Rudi Dierckx
Automated stereotactic standardization of brain SPECT receptor data using single-photon transmission images.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2001;42(2):361-75.
2001: Guy Vingerhoets; Patrick Santens; Koen Van Laere; Philippe Lahorte; Rudi A Dierckx; J De Reuck
Regional brain activity during different paradigms of mental rotation in healthy volunteers: a positron emission tomography study.
NeuroImage 2001;13(2):381-91.
2001: Koen Van Laere; Michel Koole; Jan Versijpt; Rudi Dierckx
Non-uniform versus uniform attenuation correction in brain perfusion SPET of healthy volunteers.
European journal of nuclear medicine 2001;28(1):90-8.
2000: Koen Van Laere; Chris van der Linden; Patrick Santens; V Vandewalle; Jacques Caemaert; P L Ir; Dirk Van den Abbeele; Rudi Dierckx
99Tc(m)-ECD SPET perfusion changes by internal pallidum stimulation in Parkinson's disease.
Nuclear medicine communications 2000;21(12):1103-12.
2000: Kurt Audenaert; Boudewijn Brans; Koen Van Laere; Philippe Lahorte; Jan Versijpt; Kees van Heeringen; Rudi Dierckx
Verbal fluency as a prefrontal activation probe: a validation study using 99mTc-ECD brain SPET.
European journal of nuclear medicine 2000;27(12):1800-8.
2000: Koen Van Laere; Michel Koole; T Kauppinen; Myriam A Monsieurs; LR Bouwens; Rudi Andre Dierck
Nonuniform transmission in brain SPECT using 201Tl, 153Gd, and 99mTc static line sources: anthropomorphic dosimetry studies and influence on brain quantification.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(12):2051-62.
2000: Philippe Lahorte; Stefaan Vandenberghe; Koen Van Laere; Kurt Audenaert; Ignace Lemahieu; Rudi A Dierckx
Assessing the performance of SPM analyses of spect neuroactivation studies. Statistical Parametric Mapping.
NeuroImage 2000;12(6):757-64.
2000: Carlos De Sadeleer; Koen Van Laere; B Georges; Amy Piepsz; Hamphrey R Ham
Influence of time interval and number of blood samples on the error in renal clearance determination using a mono-exponential model: a Monte Carlo simulation.
Nuclear medicine communications 2000;21(8):741-5.
2000: Koen Van Laere; Kristl Vonck; Paul Boon; Boudewijn Brans; T Vandekerckhove; Rudi Dierckx
Vagus nerve stimulation in refractory epilepsy: SPECT activation study.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(7):1145-54.
2000: Kristl Vonck; Paul Boon; Koen Van Laere; Michel D'Havé; T Vandekerckhove; S O'Connor; Boudewijn Brans; Rudi Dierckx; Jacques de Reuck
Acute single photon emission computed tomographic study of vagus nerve stimulation in refractory epilepsy.
Epilepsia 2000;41(5):601-9.
2000: Yves D'Asseler; Michel Koole; Koen Van Laere; Stefaan Vandenberghe; LR Bouwens; Rik Van de Walle; Christophe Van De Wiele; Ignace Lemahieu; Rudi A Dierckx
PACS and multimodality in medical imaging.
Technology and health care : official journal of the European Society for Engineering and Medicine 2000;8(1):35-52.
1999: Koen Van Laere; Carlos De Sadeleer; André Dobbeleir; Axel Bossuyt; Peter Paul De Deyn; Rudi Dierckx
Quantification of 99Tcm-HMPAO brain SPET in two series of healthy volunteers using different triple-headed SPET configurations: normal databases and methodological considerations.
Nuclear medicine communications 1999;20(11):1031-40.
1999: Michel Koole; Yves D'Asseler; Koen Van Laere; Rik Van de Walle; Christophe Van De Wiele; Ignace Lemahieu; Rudi A Dierckx
MRI-SPET and SPET-SPET brain co-registration: evaluation of the performance of eight different algorithms.
Nuclear medicine communications 1999;20(7):659-69.
1999: Barbara A Pickut; R A Dierckx; André Dobbeleir; Kurt Audenaert; Koen Van Laere; Ann M Vervaet; Peter Paul De Deyn
Validation of the cerebellum as a reference region for SPECT quantification in patients suffering from dementia of the Alzheimer type.
Psychiatry research 1999;90(2):103-12.
1999: Christophe Van De Wiele; Boudewijn Brans; Raymond Vanholder; H Hoeben; Koen Van Laere; Rudi A Dierckx
Predictive value of 99Tcm-DTPA captopril scintigraphy in patients with a solitary kidney and reduced kidney function.
Nuclear medicine communications 1999;20(3):263-6.
1999: Koen Van Laere; Christophe Van De Wiele; Y Van Belle; Kurt Audenaert; Rudi Dierckx
Variability study of a non-invasive approach to the absolute quantification of cerebral blood flow with 99Tcm-ECD using aortic activity as the arterial input estimate.
Nuclear medicine communications 1999;20(1):33-40.
1998: Koen Van Laere; K Casier; Dirk Uyttendaele; W Mondelaers; Carlos De Sadeleer; M Simons; Rudi Dierckx
Technetium-99m-MDP scintigraphy and long-term follow-up of treated primary malignant bone tumors.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1998;39(9):1563-9.
1997: Christophe Van De Wiele; K Osmanagaoglu; Myriam A Monsieurs; Koen Van Laere; Jean-Marc Kaufman; Rudi A Dierckx
201Tl scintigraphy does not allow visualization of the thyroid in euthyroid and hyperthyroid patients treated with amiodarone.
Nuclear medicine communications 1997;18(6):513-6.