FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

P L E M van Lent

Research Profile

Living Beings

Disorders

Anatomy

Chemicals & Drugs

Procedures

Injections, Intra-Articular

Co-author Network

Publications

TOP 3
P L E M van Lent; Thomas Vogl; Arjen B Blom; Hans Cats; Floris P J G Lafeber; Willem F Lems; Johannes Roth; Rik F P Schelbergen; Annet W Slöetjes; Wim B van den Berg
Active involvement of alarmins S100A8 and S100A9 in the regulation of synovial activation and joint destruction during mouse and human osteoarthritis.
Rik F P Schelbergen; B Wim Schreurs; Annet W Slöetjes; Wim B van den Berg; Martijn H J van den Bosch; Shahla Abdollahi-Roodsaz; Arjen B Blom; John S Mort; Johannes Roth; Thomas Vogl; P L E M van Lent
Alarmins S100A8 and S100A9 elicit a catabolic effect in human osteoarthritic chondrocytes that is dependent on Toll-like receptor 4.
Wouter Hofkens; Pieter J M Leenen; Gert Storm; Wim B van den Berg; Teun J de Vries; Vincent Everts; Lilyanne C Grevers; Birgitte Walgreen; P L E M van Lent
Intravenously delivered glucocorticoid liposomes inhibit osteoclast activity and bone erosion in murine antigen-induced arthritis.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of P L E M van Lent (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: P L E M van Lent; Thomas Vogl; Arjen B Blom; Hans Cats; Floris P J G Lafeber; Willem F Lems; Johannes Roth; Rik F P Schelbergen; Annet W Slöetjes; Wim B van den Berg
Active involvement of alarmins S100A8 and S100A9 in the regulation of synovial activation and joint destruction during mouse and human osteoarthritis.
Arthritis and rheumatism 2012;64(5):1466-76.
2012: Rik F P Schelbergen; B Wim Schreurs; Annet W Slöetjes; Wim B van den Berg; Martijn H J van den Bosch; Shahla Abdollahi-Roodsaz; Arjen B Blom; John S Mort; Johannes Roth; Thomas Vogl; P L E M van Lent
Alarmins S100A8 and S100A9 elicit a catabolic effect in human osteoarthritic chondrocytes that is dependent on Toll-like receptor 4.
Arthritis and rheumatism 2012;64(5):1477-87.
2011: Wouter Hofkens; Pieter J M Leenen; Gert Storm; Wim B van den Berg; Teun J de Vries; Vincent Everts; Lilyanne C Grevers; Birgitte Walgreen; P L E M van Lent
Intravenously delivered glucocorticoid liposomes inhibit osteoclast activity and bone erosion in murine antigen-induced arthritis.
Journal of controlled release : official journal of the Controlled Release Society 2011;152(3):363-9.
2011: Lilyanne C Grevers; Teun J de Vries; Thomas Vogl; Shahla Abdollahi-Roodsaz; Annet Sloetjes; Pieter J M Leenen; Johannes Roth; Vincent Everts; Wim B van den Berg; P L E M van Lent
S100A8 enhances osteoclastic bone resorption in vitro through activation of Toll-like receptor 4: implications for bone destruction in murine antigen-induced arthritis.
Arthritis and rheumatism 2011;63(5):1365-75.
2010: P L E M van Lent; Lilyanne C Grevers; Rik Schelbergen; Arjen Blom; Jeroen Geurts; Annet Sloetjes; Thomas Vogl; Johannes Roth; Wim B van den Berg
S100A8 causes a shift toward expression of activatory Fcγ receptors on macrophages via toll-like receptor 4 and regulates Fcγ receptor expression in synovium during chronic experimental arthritis.
Arthritis and rheumatism 2010;62(11):3353-64.
2010: Bas Heinhuis; Marije I Koenders; Fons A J van de Loo; P L E M van Lent; Soo-Hyun Kim; Charles A Dinarello; Leo A B Joosten; Wim B van den Berg
IL-32gamma and Streptococcus pyogenes cell wall fragments synergise for IL-1-dependent destructive arthritis via upregulation of TLR-2 and NOD2.
Annals of the rheumatic diseases 2010;69(10):1866-72.
2010: Arjen B Blom; P L E M van Lent; Peter van der Kraan; Wim B van den Berg
To seek shelter from the WNT in osteoarthritis? WNT-signaling as a target for osteoarthritis therapy.
Current drug targets 2010;11(5):620-9.
2009: P L E M van Lent; W Hofkens; Arjen B Blom; L Grevers; Annet Sloetjes; N Takahashi; L J van Tits; T Vogl; Johannes Roth; M P de Winther; Wim B van den Berg
Scavenger receptor class A type I/II determines matrix metalloproteinase-mediated cartilage destruction and chondrocyte death in antigen-induced arthritis.
Arthritis and rheumatism 2009;60(10):2954-65.
2009: Lilyanne C Grevers; P L E M van Lent; Marije I Koenders; Birgitte Walgreen; Annet Sloetjes; Falk Nimmerjahn; J Sjef Verbeek; Wim B van den Berg
Different amplifying mechanisms of interleukin-17 and interferon-gamma in Fcgamma receptor-mediated cartilage destruction in murine immune complex-mediated arthritis.
Arthritis and rheumatism 2009;60(2):396-407.
2009: Arjen B Blom; Sarah M Brockbank; P L E M van Lent; Henk M van Beuningen; Jeroen Geurts; Nozomi Takahashi; Peter van der Kraan; Fons A J van de Loo; B Willem Schreurs; Kristen Clements; Peter Newham; Wim B van den Berg
Involvement of the Wnt signaling pathway in experimental and human osteoarthritis: prominent role of Wnt-induced signaling protein 1.
Arthritis and rheumatism 2009;60(2):501-12.
2009: P L E M van Lent; Gerard C Krijger; Wouter Hofkens; Victor A Nievaart; Annet Sloetjes; Ray L Moss; Gerben A Koning; Wim B van den Berg
Selectively induced death of macrophages in the synovial lining of murine knee joints using 10B-liposomes and boron neutron capture synovectomy.
International journal of radiation biology 2009;85(10):860-71.
2008: P L E M van Lent; L C Grevers; Arjen B Blom; Onno J Arntz; Fons A J van de Loo; Peter van der Kraan; Shahla Abdollahi-Roodsaz; G Srikrishna; H Freeze; Annet Sloetjes; W Nacken; T Vogl; Johannes Roth; Wim B van den Berg
Stimulation of chondrocyte-mediated cartilage destruction by S100A8 in experimental murine arthritis.
Arthritis and rheumatism 2008;58(12):3776-87.
2008: Shahla Abdollahi-Roodsaz; Leo A B Joosten; Monique M A Helsen; Birgitte Walgreen; P L E M van Lent; Liduine Van Den Bersselaar; Marije I Koenders; Wim B van den Berg
Shift from toll-like receptor 2 (TLR-2) toward TLR-4 dependency in the erosive stage of chronic streptococcal cell wall arthritis coincident with TLR-4-mediated interleukin-17 production.
Arthritis and rheumatism 2008;58(12):3753-64.
2008: P L E M van Lent; L Grevers; Arjen B Blom; Annet Sloetjes; J S Mort; T Vogl; W Nacken; Wim B van den Berg; Johannes Roth
Myeloid-related proteins S100A8/S100A9 regulate joint inflammation and cartilage destruction during antigen-induced arthritis.
Annals of the rheumatic diseases 2008;67(12):1750-8.
2008: Peter I Boross; P L E M van Lent; Javier Martin-Ramirez; Jos van der Kaa; Melissa H C M Mulder; Jill W C Claassens; Wim B van den Berg; Victoria L Arandhara; Sjef Verbeek
Destructive arthritis in the absence of both FcgammaRI and FcgammaRIII.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(7):5083-91.
2007: Wim B van den Berg; P L E M van Lent; Leo A B Joosten; Shahla Abdollahi-Roodsaz; Marije I Koenders
Amplifying elements of arthritis and joint destruction.
Annals of the rheumatic diseases 2007;66 Suppl 3():iii45-8.
2007: P L E M van Lent; Arjen B Blom; L Grevers; Annet Sloetjes; Wim B van den Berg
Toll-like receptor 4 induced FcgammaR expression potentiates early onset of joint inflammation and cartilage destruction during immune complex arthritis: Toll-like receptor 4 largely regulates FcgammaR expression by interleukin 10.
Annals of the rheumatic diseases 2007;66(3):334-40.
2007: Wim B van den Berg; Leo A B Joosten; P L E M van Lent
Murine antigen-induced arthritis.
Methods in molecular medicine 2007;136():243-53.
2007: Esmeralda N Blaney Davidson; Elly L Vitters; P L E M van Lent; Fons A J van de Loo; Wim B van den Berg; Peter van der Kraan
Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling.
Arthritis research & therapy 2007;9(5):R102.
2007: Arjen B Blom; P L E M van Lent; Sten Libregts; A E M Holthuysen; Peter van der Kraan; Nico van Rooijen; Wim B van den Berg
Crucial role of macrophages in matrix metalloproteinase-mediated cartilage destruction during experimental osteoarthritis: involvement of matrix metalloproteinase 3.
Arthritis and rheumatism 2007;56(1):147-57.
2006: P L E M van Lent; Lilyanne Grevers; Erik Lubberts; Teun J de Vries; K C A M Nabbe; Sjef Verbeek; Birgit Oppers; Annet Sloetjes; Arjen B Blom; Wim B van den Berg
Fcgamma receptors directly mediate cartilage, but not bone, destruction in murine antigen-induced arthritis: uncoupling of cartilage damage from bone erosion and joint inflammation.
Arthritis and rheumatism 2006;54(12):3868-77.
2006: P L E M van Lent; Annet Sloetjes; A Blom; G Krijger; G Koning; S Nievaart; Wim B van den Berg; R Moss
Selective elimination of synovial macrophages by boron neutron capture therapy prevents onset of murine experimental arthritis.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):e106-7.
2005: Timothy Radstake; K C A M Nabbe; Mark Wenink; Mieke F Roelofs; A Oosterlaar; Antoine W T van Lieshout; Pilar Barrera; P L E M van Lent; Wim B van den Berg
Dendritic cells from patients with rheumatoid arthritis lack the interleukin 13 mediated increase of Fc gamma RII expression, which has clear functional consequences.
Annals of the rheumatic diseases 2005;64(12):1737-43.
2005: K C A M Nabbe; Peter I Boross; A E M Holthuysen; A W Sloëtjes; Jay K Kolls; Sjef Verbeek; P L E M van Lent; Wim B van den Berg
Joint inflammation and chondrocyte death become independent of Fcgamma receptor type III by local overexpression of interferon-gamma during immune complex-mediated arthritis.
Arthritis and rheumatism 2005;52(3):967-74.
2005: P L E M van Lent; Paul Span; Annet Sloetjes; Timothy Radstake; Antoine W T van Lieshout; Joop J T M Heuvel; C G J Sweep; Wim B van den Berg
Expression and localisation of the new metalloproteinase inhibitor RECK (reversion inducing cysteine-rich protein with Kazal motifs) in inflamed synovial membranes of patients with rheumatoid arthritis.
Annals of the rheumatic diseases 2005;64(3):368-74.
2005: P L E M van Lent; K C A M Nabbe; Arjen B Blom; Annet Sloetjes; A E M Holthuysen; Jay K Kolls; Fons A J van de Loo; Steven M Holland; Wim B van den Berg
NADPH-oxidase-driven oxygen radical production determines chondrocyte death and partly regulates metalloproteinase-mediated cartilage matrix degradation during interferon-gamma-stimulated immune complex arthritis.
Arthritis research & therapy 2005;7(4):R885-95.
2005: K C A M Nabbe; P L E M van Lent; A E M Holthuysen; Annet W Sloëtjes; Alisa E Koch; Timothy Radstake; Wim B van den Berg
Local IL-13 gene transfer prior to immune-complex arthritis inhibits chondrocyte death and matrix-metalloproteinase-mediated cartilage matrix degradation despite enhanced joint inflammation.
Arthritis research & therapy 2005;7(2):R392-401.
2004: Timothy Radstake; Arjen B Blom; Annet W Slöetjes; E O F van Gorselen; Gerard J Pesman; Linda P H Engelen; Ruurd Torensma; Wim B van den Berg; Carl G Figdor; P L E M van Lent; Gosse J Adema; Pilar Barrera
Increased FcgammaRII expression and aberrant tumour necrosis factor alpha production by mature dendritic cells from patients with active rheumatoid arthritis.
Annals of the rheumatic diseases 2004;63(12):1556-63.
2004: Arjen B Blom; P L E M van Lent; A E M Holthuysen; Peter van der Kraan; Johannes Roth; Nico van Rooijen; Wim B van den Berg
Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2004;12(8):627-35.
2004: Timothy Radstake; P L E M van Lent; Gerard J Pesman; Arjen B Blom; Fred G J Sweep; J Rönnelid; Gosse J Adema; Pilar Barrera; Wim B van den Berg
High production of proinflammatory and Th1 cytokines by dendritic cells from patients with rheumatoid arthritis, and down regulation upon FcgammaR triggering.
Annals of the rheumatic diseases 2004;63(6):696-702.
2004: Josbert M Metselaar; Wim B van den Berg; A E M Holthuysen; Marca H M Wauben; Gert Storm; P L E M van Lent
Liposomal targeting of glucocorticoids to synovial lining cells strongly increases therapeutic benefit in collagen type II arthritis.
Annals of the rheumatic diseases 2004;63(4):348-53.
2004: P L E M van Lent; Arjen B Blom; Peter van der Kraan; A E M Holthuysen; Elly L Vitters; Nico van Rooijen; Ruben L Smeets; K C A M Nabbe; Wim B van den Berg
Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation.
Arthritis and rheumatism 2004;50(1):103-11.
2003: P L E M van Lent; K C A M Nabbe; Peter I Boross; Arjen B Blom; Johannes Roth; A E M Holthuysen; Annet Sloetjes; Sjef Verbeek; Wim B van den Berg
The inhibitory receptor FcgammaRII reduces joint inflammation and destruction in experimental immune complex-mediated arthritides not only by inhibition of FcgammaRI/III but also by efficient clearance and endocytosis of immune complexes.
The American journal of pathology 2003;163(5):1839-48.
2003: Fons A J van de Loo; Miranda B Bennink; Onno J Arntz; Ruben L Smeets; Erik Lubberts; Leo A B Joosten; P L E M van Lent; Christina J J Coenen-de Roo; Salvatore Cuzzocrea; Brahm H Segal; Steven M Holland; Wim B van den Berg
Deficiency of NADPH oxidase components p47phox and gp91phox caused granulomatous synovitis and increased connective tissue destruction in experimental arthritis models.
The American journal of pathology 2003;163(4):1525-37.
2003: K C A M Nabbe; P L E M van Lent; A E M Holthuysen; Jay K Kolls; Sjef Verbeek; Wim B van den Berg
FcgammaRI up-regulation induced by local adenoviral-mediated interferon-gamma production aggravates chondrocyte death during immune complex-mediated arthritis.
The American journal of pathology 2003;163(2):743-52.
2003: Alfons S K de Hooge; Fons A J van de Loo; Miranda B Bennink; Onno J Arntz; Theo J W Fiselier; Marcel J A M Franssen; Leo A B Joosten; P L E M van Lent; Carl D Richards; Wim B van den Berg
Growth plate damage, a feature of juvenile idiopathic arthritis, can be induced by adenoviral gene transfer of oncostatin M: a comparative study in gene-deficient mice.
Arthritis and rheumatism 2003;48(6):1750-61.
2003: Arjen B Blom; P L E M van Lent; A E M Holthuysen; C Jacobs; Wim B van den Berg
Skewed balance in basal expression and regulation of activating v inhibitory Fcgamma receptors in macrophages of collagen induced arthritis sensitive mice.
Annals of the rheumatic diseases 2003;62(5):465-71.
2003: Arjen B Blom; Timothy Radstake; A E M Holthuysen; Annet W Slöetjes; Gerard J Pesman; Fred G J Sweep; Fons A J van de Loo; Leo A B Joosten; Pilar Barrera; P L E M van Lent; Wim B van den Berg
Increased expression of Fcgamma receptors II and III on macrophages of rheumatoid arthritis patients results in higher production of tumor necrosis factor alpha and matrix metalloproteinase.
Arthritis and rheumatism 2003;48(4):1002-14.
2003: P L E M van Lent; Carl G Figdor; Pilar Barrera; Karin van Ginkel; Annet W Slöetjes; Wim B van den Berg; Ruurd Torensma
Expression of the dendritic cell-associated C-type lectin DC-SIGN by inflammatory matrix metalloproteinase-producing macrophages in rheumatoid arthritis synovium and interaction with intercellular adhesion molecule 3-positive T cells.
Arthritis and rheumatism 2003;48(2):360-9.
2003: Leo A B Joosten; Timothy Radstake; Erik Lubberts; Liduine Van Den Bersselaar; P L C M van Riel; P L E M van Lent; Pilar Barrera; Wim B van den Berg
Association of interleukin-18 expression with enhanced levels of both interleukin-1beta and tumor necrosis factor alpha in knee synovial tissue of patients with rheumatoid arthritis.
Arthritis and rheumatism 2003;48(2):339-47.
2003: K C A M Nabbe; Arjen B Blom; A E M Holthuysen; Peter I Boross; Johannes Roth; Sjef Verbeek; P L E M van Lent; Wim B van den Berg
Coordinate expression of activating Fc gamma receptors I and III and inhibiting Fc gamma receptor type II in the determination of joint inflammation and cartilage destruction during immune complex-mediated arthritis.
Arthritis and rheumatism 2003;48(1):255-65.
2002: P L E M van Lent; A E M Holthuysen; Annet W Slöetjes; Erik Lubberts; Wim B van den Berg
Local overexpression of adeno-viral IL-4 protects cartilage from metallo proteinase-induced destruction during immune complex-mediated arthritis by preventing activation of pro-MMPs.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2002;10(3):234-43.
2002: Josbert M Metselaar; Marca H M Wauben; Otto Boerman; P L E M van Lent; Gert Storm
Long-circulating liposomes for i.v. targeted delivery of glucocorticoids in arthritis.
Cellular & molecular biology letters 2002;7(2):291-2.
2001: P L E M van Lent; K C A M Nabbe; Arjen B Blom; A E M Holthuysen; Annet Sloetjes; L B A Van De Putte; Sjef Verbeek; Wim B van den Berg
Role of activatory Fc gamma RI and Fc gamma RIII and inhibitory Fc gamma RII in inflammation and cartilage destruction during experimental antigen-induced arthritis.
The American journal of pathology 2001;159(6):2309-20.
2001: P L E M van Lent; R Licht; H Dijkman; A E M Holthuysen; J H Berden; Wim B van den Berg
Uptake of apoptotic leukocytes by synovial lining macrophages inhibits immune complex-mediated arthritis.
Journal of leukocyte biology 2001;70(5):708-14.
2001: Andrew C Bakker; Fons A J van de Loo; Henk M van Beuningen; P Sime; P L E M van Lent; Peter van der Kraan; C D Richards; Wim B van den Berg
Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2001;9(2):128-36.
2000: Wim B van den Berg; Leo A B Joosten; Erik Lubberts; Fons A J van de Loo; P L E M van Lent
Cytokine directed targeting in chronic arthritis.
European cytokine network 2000;11(3):481-2.
2000: Pilar Barrera; A Blom; P L E M van Lent; L van Bloois; J H Beijnen; N van Rooijen; Maarten C de Waal Malefijt; L B A Van De Putte; G Storm; Wim B van den Berg
Synovial macrophage depletion with clodronate-containing liposomes in rheumatoid arthritis.
Arthritis and rheumatism 2000;43(9):1951-9.
2000: Pilar Barrera; CJ van der Laken; Otto Boerman; Wim J G Oyen; MT van de Ven; P L E M van Lent; L B van de Putte; Frans H M Corstens
Radiolabelled interleukin-1 receptor antagonist for detection of synovitis in patients with rheumatoid arthritis.
Rheumatology (Oxford, England) 2000;39(8):870-4.
2000: P L E M van Lent; A J van Vuuren; Arjen B Blom; A E M Holthuysen; L B A Van De Putte; J G van de Winkel; Wim B van den Berg
Role of Fc receptor gamma chain in inflammation and cartilage damage during experimental antigen-induced arthritis.
Arthritis and rheumatism 2000;43(4):740-52.
2000: Arjen B Blom; P L E M van Lent; H van Vuuren ; A E M Holthuysen; C Jacobs; L B A Van De Putte; J G van de Winkel ; Wim B van den Berg
Fc gamma R expression on macrophages is related to severity and chronicity of synovial inflammation and cartilage destruction during experimental immune-complex-mediated arthritis (ICA).
Arthritis research 2000;2(6):489-503.
1999: Arjen B Blom; P L E M van Lent; A E M Holthuysen; Wim B van den Berg
Immune complexes, but not streptococcal cell walls or zymosan, cause chronic arthritis in mouse strains susceptible for collagen type II auto-immune arthritis.
Cytokine 1999;11(12):1046-56.
1999: JB Van Meurs; P L E M van Lent; A E M Holthuysen; D Lambrou; Ellen K Bayne; Irwin I Singer; Wim B van den Berg
Active matrix metalloproteinases are present in cartilage during immune complex-mediated arthritis: a pivotal role for stromelysin-1 in cartilage destruction.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(10):5633-9.
1999: JB Van Meurs; P L E M van Lent; reinout stoop; A E M Holthuysen; Irwin I Singer; Ellen K Bayne; J Mudgett; R Poole; C Billinghurst; Peter van der Kraan; Pieter Buma; Wim B van den Berg
Cleavage of aggrecan at the Asn341-Phe342 site coincides with the initiation of collagen damage in murine antigen-induced arthritis: a pivotal role for stromelysin 1 in matrix metalloproteinase activity.
Arthritis and rheumatism 1999;42(10):2074-84.
1999: JB Van Meurs; P L E M van Lent; A E M Holthuysen; Irwin I Singer; Ellen K Bayne; Wim B van den Berg
Kinetics of aggrecanase- and metalloproteinase-induced neoepitopes in various stages of cartilage destruction in murine arthritis.
Arthritis and rheumatism 1999;42(6):1128-39.
1999: JB Van Meurs; P L E M van Lent; A A van de Loo; A E M Holthuysen; Ellen K Bayne; Irwin I Singer; Wim B van den Berg
Increased vulnerability of postarthritic cartilage to a second arthritic insult: accelerated MMP activity in a flare up of arthritis.
Annals of the rheumatic diseases 1999;58(6):350-6.
1998: P L E M van Lent; A E M Holthuysen; N Van Rooijen; L B A Van De Putte; Wim B van den Berg
Local removal of phagocytic synovial lining cells by clodronate-liposomes decreases cartilage destruction during collagen type II arthritis.
Annals of the rheumatic diseases 1998;57(7):408-13.
1998: P L E M van Lent; A E M Holthuysen; N van Rooijen; Fons A J van de Loo; L B A Van De Putte; Wim B van den Berg
Phagocytic synovial lining cells regulate acute and chronic joint inflammation after antigenic exacerbation of smouldering experimental murine arthritis.
The Journal of rheumatology 1998;25(6):1135-45.
1998: JB Van Meurs; P L E M van Lent; Irwin I Singer; Ellen K Bayne; Fons A J van de Loo; Wim B van den Berg
Interleukin-1 receptor antagonist prevents expression of the metalloproteinase-generated neoepitope VDIPEN in antigen-induced arthritis.
Arthritis and rheumatism 1998;41(4):647-56.
1998: Fons A J van de Loo; Onno J Arntz; F H van Enckevort; P L E M van Lent; Wim B van den Berg
Reduced cartilage proteoglycan loss during zymosan-induced gonarthritis in NOS2-deficient mice and in anti-interleukin-1-treated wild-type mice with unabated joint inflammation.
Arthritis and rheumatism 1998;41(4):634-46.
1997: P L E M van Lent; A Blom; A E M Holthuysen; C W Jacobs; L B A Van De Putte; Wim B van den Berg
Monocytes/macrophages rather than PMN are involved in early cartilage degradation in cationic immune complex arthritis in mice.
Journal of leukocyte biology 1997;61(3):267-78.
1997: JB Van Meurs; P L E M van Lent; L A Joosten; Peter van der Kraan; Wim B van den Berg
Quantification of mRNA levels in joint capsule and articular cartilage of the murine knee joint by RT-PCR: kinetics of stromelysin and IL-1 mRNA levels during arthritis.
Rheumatology international 1997;16(5):197-205.
1996: Wim B van den Berg; P L E M van Lent
The role of macrophages in chronic arthritis.
Immunobiology 1996;195(4-5):614-23.
1996: P L E M van Lent; A E M Holthuysen; L A van den Bersselaar; N van Rooijen; Leo A B Joosten; Fons A J van de Loo; L B A Van De Putte; Wim B van den Berg
Phagocytic lining cells determine local expression of inflammation in type II collagen-induced arthritis.
Arthritis and rheumatism 1996;39(9):1545-55.
1995: P L E M van Lent; Fons A J van de Loo; A E M Holthuysen; L A Van Den Bersselaar; H Vermeer; Wim B van den Berg
Major role for interleukin 1 but not for tumor necrosis factor in early cartilage damage in immune complex arthritis in mice.
The Journal of rheumatology 1995;22(12):2250-8.
1995: Fons A J van de Loo; Leo A B Joosten; P L E M van Lent; Onno J Arntz; Wim B van den Berg
Role of interleukin-1, tumor necrosis factor alpha, and interleukin-6 in cartilage proteoglycan metabolism and destruction. Effect of in situ blocking in murine antigen- and zymosan-induced arthritis.
Arthritis and rheumatism 1995;38(2):164-72.
1995: A A van de Loo; Onno J Arntz; Andrew C Bakker; P L E M van Lent; M J Jacobs; Wim B van den Berg
Role of interleukin 1 in antigen-induced exacerbations of murine arthritis.
The American journal of pathology 1995;146(1):239-49.
1995: P L E M van Lent; A E M Holthuysen; L van den Bersselaar; N van Rooijen; L B A Van De Putte; Wim B van den Berg
Role of macrophage-like synovial lining cells in localization and expression of experimental arthritis.
Scandinavian journal of rheumatology. Supplement 1995;101():83-9.
1994: M J Jacobs; A E van den Hoek; P L E M van Lent; Fons A J van de Loo; L B A Van De Putte; Wim B van den Berg
Role of IL-2 and IL-4 in exacerbations of murine antigen-induced arthritis.
Immunology 1994;83(3):390-6.
1994: A G van de Langerijt; I Huitinga; Leo A B Joosten; C D Dijkstra; P L E M van Lent; Wim B van den Berg
Role of beta 2 integrins in the recruitment of phagocytic cells in joint inflammation in the rat.
Clinical immunology and immunopathology 1994;73(1):123-31.
1994: Peter van der Kraan; J de Lange; Elly L Vitters; Henk M van Beuningen; Gerjo J V M van Osch; P L E M van Lent; Wim B van den Berg
Analysis of changes in proteoglycan content in murine articular cartilage using image analysis.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 1994;2(3):207-14.
1994: A G van de Langerijt; P L E M van Lent; A R Hermus; C G J Sweep; Alexander R Cools; Wim B van den Berg
Susceptibility to adjuvant arthritis: relative importance of adrenal activity and bacterial flora.
Clinical and experimental immunology 1994;97(1):33-8.
1994: A G van de Langerijt; A E Kingston; P L E M van Lent; M E Billingham; Wim B van den Berg
Cross-reactivity to proteoglycans in bacterial arthritis: lack of evidence for in vivo role in induction of disease.
Clinical immunology and immunopathology 1994;71(3):273-80.
1994: P L E M van Lent; A E van den Hoek; L A van den Bersselaar; Fons A J van de Loo; H E Eykholt; W F Brouwer; L B A Van De Putte; Wim B van den Berg
Early cartilage degradation in cationic immune complex arthritis in mice: relative role of interleukin 1, the polymorphonuclear cell (PMN) and PMN elastase.
The Journal of rheumatology 1994;21(2):321-9.
1993: A G van de Langerijt; P L E M van Lent; A R Hermus; L B A Van De Putte; Wim B van den Berg
Regulation of resistance against adjuvant arthritis in the Fisher rat.
Clinical and experimental immunology 1993;94(1):150-5.
1993: P L E M van Lent; A E Van den Hoek; L A Van den Bersselaar; M F Spanjaards; N Van Rooijen; C D Dijkstra; L B A Van De Putte; Wim B van den Berg
In vivo role of phagocytic synovial lining cells in onset of experimental arthritis.
The American journal of pathology 1993;143(4):1226-37.
1993: P L E M van Lent; L van den Bersselaar; A E van den Hoek; M van de Ende; C D Dijkstra; N van Rooijen; L B A Van De Putte; Wim B van den Berg
Reversible depletion of synovial lining cells after intra-articular treatment with liposome-encapsulated dichloromethylene diphosphonate.
Rheumatology international 1993;13(1):21-30.
1993: Wim B van den Berg; Fons A J van de Loo; P L E M van Lent; Leo A B Joosten
Mechanisms of cartilage destruction in joint inflammation.
Agents and actions. Supplements 1993;39():49-60.
1993: P L E M van Lent; A E van den Hoek; L van den Bersselaar; N van Rooijen; Wim B van den Berg
Role of phagocytic synovial lining cells in experimental arthritis.
Agents and actions 1993;38 Spec No():C92-4.
1992: P L E M van Lent; L A van den Bersselaar; A E van den Hoek; A A van de Loo; Wim B van den Berg
Cationic immune complex arthritis in mice--a new model. Synergistic effect of complement and interleukin-1.
The American journal of pathology 1992;140(6):1451-61.
1992: P L E M van Lent; A Van den Hoek; L Van den Bersselaar; C D Dijkstra; N Van Rooijen; Wim B van den Berg
Role of synovial macrophages in experimental arthritis.
Research in immunology 1992;143(2):229-34.
1991: P L E M van Lent; Fons A J van de Loo; L van den Bersselaar; Wim B van den Berg
Chondrocyte nonresponsiveness of arthritic articular cartilage caused by short term immobilization.
The Journal of rheumatology 1991;18(5):709-15.
1991: P L E M van Lent; Leo A B Joosten; L van den Bersselaar; Wim B van den Berg
Role of PMN in early cartilage destruction.
Agents and actions 1991;32(1-2):94-5.
1990: P L E M van Lent; L van den Bersselaar; L B A Van De Putte; Wim B van den Berg
Immobilization aggravates cartilage damage during antigen-induced arthritis in mice. Attachment of polymorphonuclear leukocytes to articular cartilage.
The American journal of pathology 1990;136(6):1407-16.
1990: P L E M van Lent; L van den Bersselaar; Wim B van den Berg
Allergic arthritis induced by cationic proteins.
Agents and actions 1990;29(1-2):98-9.
1989: P L E M van Lent; F H Wilms; Wim B van den Berg
Interaction of polymorphonuclear leucocytes with patellar cartilage of immobilised arthritic joints: a scanning electron microscopic study.
Annals of the rheumatic diseases 1989;48(10):832-7.
1989: P L E M van Lent; L van den Bersselaar; G J Grutters; Wim B van den Berg
Fate of antigen after intravenous and intraarticular injection into mice. Role of molecular weight and charge.
The Journal of rheumatology 1989;16(10):1295-303.
1989: P L E M van Lent; C Dekker; J Mosterd; L van den Bersselaar; Wim B van den Berg
Allergic arthritis induced by cationic proteins: role of molecular weight.
Immunology 1989;67(4):447-52.
1989: P L E M van Lent; A A van de Loo; L van den Bersselaar; Wim B van den Berg
Short-term immobilization restores and prevents inhibition of chondrocyte synthesis caused by IL-1.
Agents and actions 1989;26(1-2):191-2.
1989: A A van de Loo; Henk M van Beuningen; P L E M van Lent; Wim B van den Berg
Direct effect of murine rIL-1 on cartilage metabolism in vivo.
Agents and actions 1989;26(1-2):153-5.
1988: P L E M van Lent; Wim B van den Berg; L B A Van De Putte; L van den Bersselaar
Electrical charge of a protein determines penetration and localization in hyaline articular cartilage. Quantitative and autoradiographic studies on cartilage of different species, including man.
Rheumatology international 1988;8(4):145-52.
1987: P L E M van Lent; Wim B van den Berg; Joost Schalkwijk; L B A Van De Putte; L van den Bersselaar
Allergic arthritis induced by cationic antigens: relationship of chronicity with antigen retention and T-cell reactivity.
Immunology 1987;62(2):265-72.
1987: P L E M van Lent; Wim B van den Berg; Joost Schalkwijk; L B A Van De Putte; L van den Bersselaar
The impact of protein size and charge on its retention in articular cartilage.
The Journal of rheumatology 1987;14(4):798-805.