Username

Password

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Fred Van Leuven

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequence

Chemicals & Drugs

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Zabrocki Piotr; Bastiaens Ilse; Delay Charlotte; Bammens Tine; Ghillebert Ruben; Pellens Klaartje; De Virgilio Claudio; Van Leuven Fred; Winderickx Joris
Phosphorylation, lipid raft interaction and traffic of alpha-synuclein in a yeast model for Parkinson.
Winderickx Joris; Delay Charlotte; De Vos Ann; Klinger Harald; Pellens Klaartje; Vanhelmont Thomas; Van Leuven Fred; Zabrocki Piotr
Protein folding diseases and neurodegeneration: lessons learned from yeast.
Hirata-Fukae Chiho; Sidahmed Elkhansa Hassan; Gooskens Thomas P; Aisen Paul S; Dewachter Ilse; Devijver Herman; Van Leuven Fred; Matsuoka Yasuji
Beta-site amyloid precursor protein-cleaving enzyme-1 (BACE1)-mediated changes of endogenous amyloid beta in wild-type and transgenic mice in vivo.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Fred Van Leuven (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2008: Zabrocki Piotr; Bastiaens Ilse; Delay Charlotte; Bammens Tine; Ghillebert Ruben; Pellens Klaartje; De Virgilio Claudio; Van Leuven Fred; Winderickx Joris
Phosphorylation, lipid raft interaction and traffic of alpha-synuclein in a yeast model for Parkinson.
Biochimica et biophysica acta 2008;1783(10):1767-80.
2008: Winderickx Joris; Delay Charlotte; De Vos Ann; Klinger Harald; Pellens Klaartje; Vanhelmont Thomas; Van Leuven Fred; Zabrocki Piotr
Protein folding diseases and neurodegeneration: lessons learned from yeast.
Biochimica et biophysica acta 2008;1783(7):1381-95.
2008: Hirata-Fukae Chiho; Sidahmed Elkhansa Hassan; Gooskens Thomas P; Aisen Paul S; Dewachter Ilse; Devijver Herman; Van Leuven Fred; Matsuoka Yasuji
Beta-site amyloid precursor protein-cleaving enzyme-1 (BACE1)-mediated changes of endogenous amyloid beta in wild-type and transgenic mice in vivo.
Neuroscience letters 2008;435(3):186-9.
2008: Terwel Dick; Muyllaert David; Dewachter Ilse; Borghgraef Peter; Croes Sophie; Devijver Herman; Van Leuven Fred
Amyloid activates GSK-3beta to aggravate neuronal tauopathy in bigenic mice.
The American journal of pathology 2008;172(3):786-98.
2008: Muyllaert David; Terwel Dick; Kremer Anna; Sennvik Kristina; Borghgraef Peter; Devijver Herman; Dewachter Ilse; Van Leuven Fred
Neurodegeneration and neuroinflammation in cdk5/p25-inducible mice: a model for hippocampal sclerosis and neocortical degeneration.
The American journal of pathology 2008;172(2):470-85.
2008: Muyllaert D; Kremer A; Jaworski T; Borghgraef P; Devijver H; Croes S; Dewachter I; Van Leuven F
Glycogen synthase kinase-3beta, or a link between amyloid and tau pathology?
Genes, brain, and behavior 2008;7 Suppl 1():57-66.
2007: Thal Dietmar Rudolf; Larionov Sergey; Abramowski Dorothee; Wiederhold Karl-Heinz; Van Dooren Tom; Yamaguchi Haruyasu; Haass Christian; Van Leuven Fred; Staufenbiel Matthias; Capetillo-Zarate Estibaliz
Occurrence and co-localization of amyloid beta-protein and apolipoprotein E in perivascular drainage channels of wild-type and APP-transgenic mice.
Neurobiology of aging 2007;28(8):1221-30.
2007: Sennvik Kristina; Boekhoorn Karin; Lasrado Reena; Terwel Dick; Verhaeghe Steven; Korr Hubert; Schmitz Christoph; Tomiyama Takami; Mori Hiroshi; Krugers Harm; Joels Marian; Ramakers Ger J A; Lucassen Paul J; Van Leuven Fred
Tau-4R suppresses proliferation and promotes neuronal differentiation in the hippocampus of tau knockin/knockout mice.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(9):2149-61.
2007: Priller Christina; Dewachter Ilse; Vassallo Neville; Paluch Sandra; Pace Claudia; Kretzschmar Hans A; Van Leuven Fred; Herms Jochen
Mutant presenilin 1 alters synaptic transmission in cultured hippocampal neurons.
The Journal of biological chemistry 2007;282(2):1119-27.
2006: Muyllaert D; Terwel D; Borghgraef P; Devijver H; Dewachter I; Van Leuven F
Transgenic mouse models for Alzheimer's disease: the role of GSK-3B in combined amyloid and tau-pathology.
Revue neurologique 2006;162(10):903-7.
2006: Vandebroek Tom; Terwel Dick; Vanhelmont Thomas; Gysemans Maarten; Van Haesendonck Chris; Engelborghs Yves; Winderickx Joris; Van Leuven Fred
Microtubule binding and clustering of human Tau-4R and Tau-P301L proteins isolated from yeast deficient in orthologues of glycogen synthase kinase-3beta or cdk5.
The Journal of biological chemistry 2006;281(35):25388-97.
2006: Boekhoorn Karin; Terwel Dick; Biemans Barbara; Borghgraef Peter; Wiegert Olof; Ramakers Ger J A; de Vos Koos; Krugers Harm; Tomiyama Takami; Mori Hiroshi; Joels Marian; van Leuven Fred; Lucassen Paul J
Improved long-term potentiation and memory in young tau-P301L transgenic mice before onset of hyperphosphorylation and tauopathy.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(13):3514-23.
2006: Griffioen Gerard; Duhamel Hein; Van Damme Nele; Pellens Klaartje; Zabrocki Piotr; Pannecouque Christophe; van Leuven Fred; Winderickx Joris; Wera Stefaan
A yeast-based model of alpha-synucleinopathy identifies compounds with therapeutic potential.
Biochimica et biophysica acta 2006;1762(3):312-8.
2006: Sastre Magdalena; Dewachter Ilse; Rossner Steffen; Bogdanovic Nenad; Rosen Evan; Borghgraef Peter; Evert Bernd O; Dumitrescu-Ozimek Lucia; Thal Dietmar R; Landreth Gary; Walter Jochen; Klockgether Thomas; van Leuven Fred; Heneka Michael T
Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(2):443-8.
2006: Van Dooren Tom; Muyllaert David; Borghgraef Peter; Cresens Annelies; Devijver Herman; Van der Auwera Ingrid; Wera Stefaan; Dewachter Ilse; Van Leuven Fred
Neuronal or glial expression of human apolipoprotein e4 affects parenchymal and vascular amyloid pathology differentially in different brain regions of double- and triple-transgenic mice.
The American journal of pathology 2006;168(1):245-60.
2005: Boldron Christophe; Van der Auwera Ingrid; Deraeve Céline; Gornitzka Heinz; Wera Stefaan; Pitié Marguerite; Van Leuven Fred; Meunier Bernard
Preparation of cyclo-phen-type ligands: chelators of metal ions as potential therapeutic agents in the treatment of neurodegenerative diseases.
Chembiochem : a European journal of chemical biology 2005;6(11):1976-80.
2005: Van der Auwera Ingrid; Wera Stefaan; Van Leuven Fred; Henderson Samuel T
A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer's disease.
Nutrition & metabolism 2005;2():28.
2005: Heneka Michael T; Sastre Magdalena; Dumitrescu-Ozimek Lucia; Dewachter Ilse; Walter Jochen; Klockgether Thomas; Van Leuven Fred
Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice.
Journal of neuroinflammation 2005;2():22.
2005: Vandebroek Tom; Vanhelmont Thomas; Terwel Dick; Borghgraef Peter; Lemaire Katleen; Snauwaert Johan; Wera Stefaan; Van Leuven Fred; Winderickx Joris
Identification and isolation of a hyperphosphorylated, conformationally changed intermediate of human protein tau expressed in yeast.
Biochemistry 2005;44(34):11466-75.
2005: Van Laer Lut; Pfister Markus; Thys Sofie; Vrijens Karen; Mueller Marcus; Umans Lieve; Serneels Lutgarde; Van Nassauw Luc; Kooy Frank; Smith Richard J H; Timmermans Jean-Pierre; Van Leuven Fred; Van Camp Guy
Mice lacking Dfna5 show a diverging number of cochlear fourth row outer hair cells.
Neurobiology of disease 2005;19(3):386-99.
2005: Heneka Michael T; Sastre Magdalena; Dumitrescu-Ozimek Lucia; Hanke Anne; Dewachter Ilse; Kuiperi Cuno; O'Banion Kerry; Klockgether Thomas; Van Leuven Fred; Landreth Gary E
Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice.
Brain : a journal of neurology 2005;128(Pt 6):1442-53.
2005: Zabrocki Piotr; Pellens Klaartje; Vanhelmont Thomas; Vandebroek Tom; Griffioen Gerard; Wera Stefaan; Van Leuven Fred; Winderickx Joris
Characterization of alpha-synuclein aggregation and synergistic toxicity with protein tau in yeast.
The FEBS journal 2005;272(6):1386-400.
2005: Vanhoutte G; Dewachter I; Borghgraef P; Van Leuven F; Van der Linden A
Noninvasive in vivo MRI detection of neuritic plaques associated with iron in APP[V717I] transgenic mice, a model for Alzheimer's disease.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2005;53(3):607-13.
2005: Terwel Dick; Lasrado Reena; Snauwaert Johan; Vandeweert Erno; Van Haesendonck Chris; Borghgraef Peter; Van Leuven Fred
Changed conformation of mutant Tau-P301L underlies the moribund tauopathy, absent in progressive, nonlethal axonopathy of Tau-4R/2N transgenic mice.
The Journal of biological chemistry 2005;280(5):3963-73.
2005: Zurbriggen Rinaldo; Amacker Mario; Kammer Andreas R; Westerfeld Nicole; Borghgraef Peter; Van Leuven Fred; Van der Auwera Ingrid; Wera Stefaan
Virosome-based active immunization targets soluble amyloid species rather than plaques in a transgenic mouse model of Alzheimer's disease.
Journal of molecular neuroscience : MN 2005;27(2):157-66.
2005: van Dooren Tom; Dewachter Ilse; Borghgraef Peter; van Leuven Fred
Transgenic mouse models for APP processing and Alzheimer's disease: early and late defects.
Sub-cellular biochemistry 2005;38():45-63.
2004: Willem Michael; Dewachter Ilse; Smyth Neil; Van Dooren Tom; Borghgraef Peter; Haass Christian; Van Leuven Fred
beta-site amyloid precursor protein cleaving enzyme 1 increases amyloid deposition in brain parenchyma but reduces cerebrovascular amyloid angiopathy in aging BACE x APP[V717I] double-transgenic mice.
The American journal of pathology 2004;165(5):1621-31.
2004: Etcheberrigaray René; Tan Mathew; Dewachter Ilse; Kuipéri Cuno; Van der Auwera Ingrid; Wera Stefaan; Qiao Lixin; Bank Barry; Nelson Thomas J; Kozikowski Alan P; Van Leuven Fred; Alkon Daniel L
Therapeutic effects of PKC activators in Alzheimer's disease transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(30):11141-6.
2003: Ris Laurence; Dewachter Ilse; Reversé Delphine; Godaux Emile; Van Leuven Fred
Capacitative calcium entry induces hippocampal long term potentiation in the absence of presenilin-1.
The Journal of biological chemistry 2003;278(45):44393-9.
2003: Sastre Magdalena; Dewachter Ilse; Landreth Gary E; Willson Timothy M; Klockgether Thomas; van Leuven Fred; Heneka Michael T
Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(30):9796-804.
2003: Gilissen Christa; de Groot Tjibbe J; Bronfman Francesca; van Leuven Fred; Verbruggen Alfons M; Bormans Guy M
Evaluation of 18F-FA-4 and 11C-pipzA-4 as radioligands for the in vivo evaluation of the high-affinity choline uptake system.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2003;44(2):269-75.
2003: Herms Jochen; Schneider Ilka; Dewachter Ilse; Caluwaerts Nathalie; Kretzschmar Hans; Van Leuven Fred
Capacitive calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein.
The Journal of biological chemistry 2003;278(4):2484-9.
2003: Van Dorpe Jo; Spittaels Kurt; Van den Haute Chris Van; Dewachter Ilse; Moechars Dieder; Geerts Hugo; Van Leuven Fred
Neuropathobiology in transgenic mice. The case of Alzheimer's disease.
Methods in molecular biology (Clifton, N.J.) 2003;209():333-61.
2002: Dewachter Ilse; Van Leuven Fred
Secretases as targets for the treatment of Alzheimer's disease: the prospects.
Lancet neurology 2002;1(7):409-16.
2002: Smeijers Liesbet; Willems Stefan; Lauwers Annick; Thiry Els; van Leuven Fred; Roebroek Anton J M
Functional expression of murine LRP1 requires correction of Lrp1 cDNA sequences.
Biochimica et biophysica acta 2002;1577(1):155-8.
2002: Gourine Alexander V; Gourine Valery N; Tesfaigzi Yohannes; Caluwaerts Nathalie; Van Leuven Fred; Kluger Matthew J
Role of alpha(2)-macroglobulin in fever and cytokine responses induced by lipopolysaccharide in mice.
American journal of physiology. Regulatory, integrative and comparative physiology 2002;283(1):R218-26.
2002: Tilleman Kelly; Van den Haute Chris; Geerts Hugo; van Leuven Fred; Esmans Eddy L; Moens Luc
Proteomics analysis of the neurodegeneration in the brain of tau transgenic mice.
Proteomics 2002;2(6):656-65.
2002: Permanne Bruno; Adessi Céline; Saborio Gabriela P; Fraga Santiago; Frossard Marie-José; Van Dorpe Jo; Dewachter Ilse; Banks William A; Van Leuven Fred; Soto Claudio
Reduction of amyloid load and cerebral damage in a transgenic mouse model of Alzheimer's disease by treatment with a beta-sheet breaker peptide.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(8):860-2.
2002: Van Dorpe Jo; Dal Cin Paola; Weremowicz Stanislawa; Van Leuven Fred; de Wever Ivo; Van den Berghe Herman; Fletcher Christopher D M; Sciot Raf
Translocation of the HMGI-C ( HMGA2) gene in a benign mesenchymoma (chondrolipoangioma).
Virchows Archiv : an international journal of pathology 2002;440(5):485-90.
2002: Dewachter Ilse; Reversé Delphine; Caluwaerts Nathalie; Ris Laurence; Kuipéri Cuno; Van den Haute Chris; Spittaels Kurt; Umans Lieve; Serneels Lutgarde; Thiry Els; Moechars Dieder; Mercken Mark; Godaux Emile; Van Leuven Fred
Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(9):3445-53.
2002: Nuydens R; Van Den Kieboom G; Nolten C; Verhulst C; Van Osta P; Spittaels K; Van den Haute C; De Feyter E; Geerts H; Van Leuven F
Coexpression of GSK-3beta corrects phenotypic aberrations of dorsal root ganglion cells, cultured from adult transgenic mice overexpressing human protein tau.
Neurobiology of disease 2002;9(1):38-48.
2002: Tilleman Kelly; Stevens Ilse; Spittaels Kurt; Haute Chris Van den; Clerens Stefan; Van Den Bergh Gert; Geerts Hugo; Van Leuven Fred; Vandesande Frans; Moens Luc
Differential expression of brain proteins in glycogen synthase kinase-3 transgenic mice: a proteomics point of view.
Proteomics 2002;2(1):94-104.
2002: Terwel Dick; Dewachter Ilse; Van Leuven Fred
Axonal transport, tau protein, and neurodegeneration in Alzheimer's disease.
Neuromolecular medicine 2002;2(2):151-65.
2002: Spittaels K; Van den Haute C; Van Dorpe J; Terwel D; Vandezande K; Lasrado R; Bruynseels K; Irizarry M; Verhoye M; Van Lint J; Vandenheede J R; Ashton D; Mercken M; Loos R; Hyman B; Van der Linden A; Geerts H; Van Leuven F
Neonatal neuronal overexpression of glycogen synthase kinase-3 beta reduces brain size in transgenic mice.
Neuroscience 2002;113(4):797-808.
2001: Schneider I; Reverse D; Dewachter I; Ris L; Caluwaerts N; Kuiperi C; Gilis M; Geerts H; Kretzschmar H; Godaux E; Moechars D; Van Leuven F; Herms J
Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation.
The Journal of biological chemistry 2001;276(15):11539-44.
2001: Van Leuven F; Thiry E; Lambrechts M; Stas L; Boon T; Bruynseels K; Muls E; Descamps O
Sequencing of the coding exons of the LRP1 and LDLR genes on individual DNA samples reveals novel mutations in both genes.
Atherosclerosis 2001;154(3):567-77.
2001: Van den Haute C; Spittaels K; Van Dorpe J; Lasrado R; Vandezande K; Laenen I; Geerts H; Van Leuven F
Coexpression of human cdk5 and its activator p35 with human protein tau in neurons in brain of triple transgenic mice.
Neurobiology of disease 2001;8(1):32-44.
2001: Dewachter I; Moechars D; van Dorpe J; Tesseur I; Van den Haute C; Spittaels K; Van Leuven F
Modelling Alzheimer's disease in multiple transgenic mice.
Biochemical Society symposium 2001;(67):203-10.
2000: Spittaels K; Van den Haute C; Van Dorpe J; Geerts H; Mercken M; Bruynseels K; Lasrado R; Vandezande K; Laenen I; Boon T; Van Lint J; Vandenheede J; Moechars D; Loos R; Van Leuven F
Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice.
The Journal of biological chemistry 2000;275(52):41340-9.
2000: Barre A; Peumans W J; Menu-Bouaouiche L; Van Damme E J; May G D; Herrera A F; Van Leuven F; Rougé P
Purification and structural analysis of an abundant thaumatin-like protein from ripe banana fruit.
Planta 2000;211(6):791-9.
2000: Tesseur I; Van Dorpe J; Bruynseels K; Bronfman F; Sciot R; Van Lommel A; Van Leuven F
Prominent axonopathy and disruption of axonal transport in transgenic mice expressing human apolipoprotein E4 in neurons of brain and spinal cord.
The American journal of pathology 2000;157(5):1495-510.
2000: Van Dorpe J; Smeijers L; Dewachter I; Nuyens D; Spittaels K; Van Den Haute C; Mercken M; Moechars D; Laenen I; Kuiperi C; Bruynseels K; Tesseur I; Loos R; Vanderstichele H; Checler F; Sciot R; Van Leuven F
Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons.
The American journal of pathology 2000;157(4):1283-98.
2000: Dewachter I; van Dorpe J; Spittaels K; Tesseur I; Van Den Haute C; Moechars D; Van Leuven F
Modeling Alzheimer's disease in transgenic mice: effect of age and of presenilin1 on amyloid biochemistry and pathology in APP/London mice.
Experimental gerontology 2000;35(6-7):831-41.
2000: Peumans W J; Zhang W; Barre A; Houlès Astoul C; Balint-Kurti P J; Rovira P; Rougé P; May G D; Van Leuven F; Truffa-Bachi P; Van Damme E J
Fruit-specific lectins from banana and plantain.
Planta 2000;211(4):546-54.
2000: Dewachter I; Van Dorpe J; Smeijers L; Gilis M; Kuipéri C; Laenen I; Caluwaerts N; Moechars D; Checler F; Vanderstichele H; Van Leuven F
Aging increased amyloid peptide and caused amyloid plaques in brain of old APP/V717I transgenic mice by a different mechanism than mutant presenilin1.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(17):6452-8.
2000: Bronfman F C; Moechars D; Van Leuven F
Acetylcholinesterase-positive fiber deafferentation and cell shrinkage in the septohippocampal pathway of aged amyloid precursor protein london mutant transgenic mice.
Neurobiology of disease 2000;7(3):152-68.
2000: Van Damme E J; Hao Q; Charels D; Barre A; Rougé P; Van Leuven F; Peumans W J
Characterization and molecular cloning of two different type 2 ribosome-inactivating proteins from the monocotyledonous plant Polygonatum multiflorum.
European journal of biochemistry / FEBS 2000;267(9):2746-59.
2000: Tesseur I; Van Dorpe J; Spittaels K; Van den Haute C; Moechars D; Van Leuven F
Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice.
The American journal of pathology 2000;156(3):951-64.
2000: Van Damme E J; Hao Q; Barre A; Rougé P; Van Leuven F; Peumans W J
Major protein of resting rhizomes of Calystegia sepium (hedge bindweed) closely resembles plant RNases but has no enzymatic activity.
Plant physiology 2000;122(2):433-46.
2000: Peumans W J; Barre A; Derycke V; Rougé P; Zhang W; May G D; Delcour J A; Van Leuven F; Van Damme E J
Purification, characterization and structural analysis of an abundant beta-1,3-glucanase from banana fruit.
European journal of biochemistry / FEBS 2000;267(4):1188-95.
2000: Kumar-Singh S; Dewachter I; Moechars D; Lübke U; De Jonghe C; Ceuterick C; Checler F; Naidu A; Cordell B; Cras P; Van Broeckhoven C; Van Leuven F
Behavioral disturbances without amyloid deposits in mice overexpressing human amyloid precursor protein with Flemish (A692G) or Dutch (E693Q) mutation.
Neurobiology of disease 2000;7(1):9-22.
2000: Bronfman F C; Tesseur I; Hofker M H; Havekens L M; Van Leuven F
No evidence for cholinergic problems in apolipoprotein E knockout and apolipoprotein E4 transgenic mice.
Neuroscience 2000;97(3):411-8.
1999: Spittaels K; Van den Haute C; Van Dorpe J; Bruynseels K; Vandezande K; Laenen I; Geerts H; Mercken M; Sciot R; Van Lommel A; Loos R; Van Leuven F
Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein.
The American journal of pathology 1999;155(6):2153-65.
1999: Umans L; Overbergh L; Serneels L; Tesseur I; Van Leuven F
Analysis of expression of genes involved in apolipoprotein E-based lipoprotein metabolism in pregnant mice deficient in the receptor-associated protein, the low density lipoprotein receptor, or apolipoprotein E.
Biology of reproduction 1999;61(5):1216-25.
1999: Herreman A; Hartmann D; Annaert W; Saftig P; Craessaerts K; Serneels L; Umans L; Schrijvers V; Checler F; Vanderstichele H; Baekelandt V; Dressel R; Cupers P; Huylebroeck D; Zwijsen A; Van Leuven F; De Strooper B
Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(21):11872-7.
1999: Umans L; Serneels L; Overbergh L; Stas L; Van Leuven F
alpha2-macroglobulin- and murinoglobulin-1- deficient mice. A mouse model for acute pancreatitis.
The American journal of pathology 1999;155(3):983-93.
1999: Lévesque L; Annaert W; Craessaerts K; Mathews P M; Seeger M; Nixon R A; Van Leuven F; Gandy S; Westaway D; St George-Hyslop P; De Strooper B; Fraser P E
Developmental expression of wild-type and mutant presenilin-1 in hippocampal neurons from transgenic mice: evidence for novel species-specific properties of human presenilin-1.
Molecular medicine (Cambridge, Mass.) 1999;5(8):542-54.
1999: Bonaventure P; Umans L; Bakker M H; Cras P; Langlois X; Luyten W H; Megens A A; Serneels L; Van Leuven F; Leysen J E
Humanization of mouse 5-hydroxytryptamine1B receptor gene by homologous recombination: in vitro and in vivo characterization.
Molecular pharmacology 1999;56(1):54-67.
1999: Wavrant-DeVrièze F; Lambert J C; Stas L; Crook R; Cottel D; Pasquier F; Frigard B; Lambrechts M; Thiry E; Amouyel P; Tur J P; Chartier-Harlin M C; Hardy J; Van Leuven F
Association between coding variability in the LRP gene and the risk of late-onset Alzheimer's disease.
Human genetics 1999;104(5):432-4.
1999: Wright L M; Van Damme E J; Barre A; Allen A K; Van Leuven F; Reynolds C D; Rouge P; Peumans W J
Isolation, characterization, molecular cloning and molecular modelling of two lectins of different specificities from bluebell (Scilla campanulata) bulbs.
The Biochemical journal 1999;340 ( Pt 1)():299-308.
1999: Van Damme E J; Charels D; Roy S; Tierens K; Barre A; Martins J C; Rougé P; Van Leuven F; Does M; Peumans W J
A gene encoding a hevein-like protein from elderberry fruits is homologous to PR-4 and class V chitinase genes.
Plant physiology 1999;119(4):1547-56.
1999: Moechars D; Dewachter I; Lorent K; Reversé D; Baekelandt V; Naidu A; Tesseur I; Spittaels K; Haute C V; Checler F; Godaux E; Cordell B; Van Leuven F
Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain.
The Journal of biological chemistry 1999;274(10):6483-92.
1999: Umans L; Serneels L; Lorent K; Dewachter I; Tesseur I; Moechars D; Van Leuven F
Lipoprotein receptor-related protein in brain and in cultured neurons of mice deficient in receptor-associated protein and transgenic for apolipoprotein E4 or amyloid precursor protein.
Neuroscience 1999;94(1):315-21.
1999: Moechars D; Lorent K; Van Leuven F
Premature death in transgenic mice that overexpress a mutant amyloid precursor protein is preceded by severe neurodegeneration and apoptosis.
Neuroscience 1999;91(3):819-30.
1998: Van Leuven F; Torrekens S; Moechars D; Hilliker C; Buellens M; Bollen M; Delabie J
Molecular cloning of a gene on chromosome 19q12 coding for a novel intracellular protein: analysis of expression in human and mouse tissues and in human tumor cells, particularly Reed-Sternberg cells in Hodgkin disease.
Genomics 1998;54(3):511-20.
1998: Roebroek A J; Umans L; Pauli I G; Robertson E J; van Leuven F; Van de Ven W J; Constam D B
Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin.
Development (Cambridge, England) 1998;125(24):4863-76.
1998: Moechars D; Gilis M; Kuipéri C; Laenen I; Van Leuven F
Aggressive behaviour in transgenic mice expressing APP is alleviated by serotonergic drugs.
Neuroreport 1998;9(16):3561-4.
1998: Van Leuven F; Thiry E; Stas L; Nelissen B
Analysis of the human LRPAP1 gene coding for the lipoprotein receptor-associated protein: identification of 22 polymorphisms and one mutation.
Genomics 1998;52(2):145-51.
1998: Van Leuven F; Stas L; Thiry E; Nelissen B; Miyake Y
Strategy to sequence the 89 exons of the human LRP1 gene coding for the lipoprotein receptor related protein: identification of one expressed mutation among 48 polymorphisms.
Genomics 1998;52(2):138-44.
1998: Moechars D; Lorent K; Dewachter I; Baekelandt V; De Strooper B; Van Leuven F
Transgenic mice expressing an alpha-secretion mutant of the amyloid precursor protein in the brain develop a progressive CNS disorder.
Behavioural brain research 1998;95(1):55-64.
1998: Peumans W J; Roy S; Barre A; Rouge P; van Leuven F; van Damme E J
Elderberry (Sambucus nigra) contains truncated Neu5Ac(alpha-2,6)Gal/GalNAc-binding type 2 ribosome-inactivating proteins.
FEBS letters 1998;425(1):35-9.
1998: De Strooper B; Saftig P; Craessaerts K; Vanderstichele H; Guhde G; Annaert W; Von Figura K; Van Leuven F
Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein.
Nature 1998;391(6665):387-90.
1997: Van Damme E J; Roy S; Barre A; Rougé P; Van Leuven F; Peumans W J
The major elderberry (Sambucus nigra) fruit protein is a lectin derived from a truncated type 2 ribosome-inactivating protein.
The Plant journal : for cell and molecular biology 1997;12(6):1251-60.
1997: Smeets K; Van Damme E J; Van Leuven F; Peumans W J
Isolation, characterization and molecular cloning of a leaf-specific lectin from ramsons (Allium ursinum L.).
Plant molecular biology 1997;35(4):531-5.
1997: Van Damme E J; Van Leuven F; Peumans W J
Isolation, characterization and molecular cloning of the bark lectins from Maackia amurensis.
Glycoconjugate journal 1997;14(4):449-56.
1997: Van Damme E J; Barre A; Barbieri L; Valbonesi P; Rouge P; Van Leuven F; Stirpe F; Peumans W J
Type 1 ribosome-inactivating proteins are the most abundant proteins in iris (Iris hollandica var. Professor Blaauw) bulbs: characterization and molecular cloning.
The Biochemical journal 1997;324 ( Pt 3)():963-70.
1997: Van Damme E J; Roy S; Barre A; Citores L; Mostafapous K; Rougé P; Van Leuven F; Girbés T; Goldstein I J; Peumans W J
Elderberry (Sambucus nigra) bark contains two structurally different Neu5Ac(alpha2,6)Gal/GalNAc-binding type 2 ribosome-inactivating proteins.
European journal of biochemistry / FEBS 1997;245(3):648-55.
1997: Smeets K; Van Damme E J; Van Leuven F; Peumans W J
Isolation and characterization of lectins and lectin-alliinase complexes from bulbs of garlic (Allium sativum) and ramsons (Allium ursinum).
Glycoconjugate journal 1997;14(3):331-43.
1997: Van Damme E J; Barre A; Rougé P; Van Leuven F; Peumans W J
Isolation and molecular cloning of a novel type 2 ribosome-inactivating protein with an inactive B chain from elderberry (Sambucus nigra) bark.
The Journal of biological chemistry 1997;272(13):8353-60.
1997: Peumans W J; Winter H C; Bemer V; Van Leuven F; Goldstein I J; Truffa-Bachi P; Van Damme E J
Isolation of a novel plant lectin with an unusual specificity from Calystegia sepium.
Glycoconjugate journal 1997;14(2):259-65.
1997: De Strooper B; Beullens M; Contreras B; Levesque L; Craessaerts K; Cordell B; Moechars D; Bollen M; Fraser P; George-Hyslop P S; Van Leuven F
Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins.
The Journal of biological chemistry 1997;272(6):3590-8.
1997: Smeets K; Van Damme E J; Verhaert P; Barre A; Rougé P; Van Leuven F; Peumans W J
Isolation, characterization and molecular cloning of the mannose-binding lectins from leaves and roots of garlic (Allium sativum L.).
Plant molecular biology 1997;33(2):223-34.
1997: Peumans W J; Smeets K; Van Nerum K; Van Leuven F; Van Damme E J
Lectin and alliinase are the predominant proteins in nectar from leek (Allium porrum L.) flowers.
Planta 1997;201(3):298-302.
1996: Baumgart E; Vanhooren J C; Fransen M; Van Leuven F; Fahimi H D; Van Veldhoven P P; Mannaerts G P
Molecular cloning and further characterization of rat peroxisomal trihydroxycoprostanoyl-CoA oxidase.
The Biochemical journal 1996;320 ( Pt 1)():115-21.
1996: Saftig P; Peters C; von Figura K; Craessaerts K; Van Leuven F; De Strooper B
Amyloidogenic processing of human amyloid precursor protein in hippocampal neurons devoid of cathepsin D.
The Journal of biological chemistry 1996;271(44):27241-4.
1996: De Bolle M F; Osborn R W; Goderis I J; Noe L; Acland D; Hart C A; Torrekens S; Van Leuven F; Broekaert W F
Antimicrobial peptides from Mirabilis jalapa and Amaranthus caudatus: expression, processing, localization and biological activity in transgenic tobacco.
Plant molecular biology 1996;31(5):993-1008.
1996: Vanhooren J C; Fransen M; de Béthune B; Baumgart E; Baes M; Torrekens S; Van Leuven F; Mannaerts G P; Van Veldhoven P P
Rat pristanoyl-CoA oxidase. cDNA cloning and recognition of its C-terminal (SQL) by the peroxisomal-targeting signal 1 receptor.
European journal of biochemistry / FEBS 1996;239(2):302-9.
1996: Van Damme E J; Barre A; Rougé P; Van Leuven F; Balzarini J; Peumans W J
Molecular cloning of the lectin and a lectin-related protein from common Solomon's seal (Polygonatum multiflorum).
Plant molecular biology 1996;31(3):657-72.
1996: Berghman L R; Lescroart O; Roelants I; Ollevier F; Kühn E R; Verhaert P D; De Loof A; van Leuven F; Vandesande F
One-step immunoaffinity purification and partial characterization of hypophyseal growth hormone from the African catfish, Clarias gariepinus (Burchell).
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 1996;113(4):773-80.
1996: Van Damme E J; Barre A; Rougé P; Van Leuven F; Peumans W J
Characterization and molecular cloning of Sambucus nigra agglutinin V (nigrin b), a GalNAc-specific type-2 ribosome-inactivating protein from the bark of elderberry (Sambucus nigra).
European journal of biochemistry / FEBS 1996;237(2):505-13.
1996: Moechars D; Lorent K; De Strooper B; Dewachter I; Van Leuven F
Expression in brain of amyloid precursor protein mutated in the alpha-secretase site causes disturbed behavior, neuronal degeneration and premature death in transgenic mice.
The EMBO journal 1996;15(6):1265-74.
1996: Van Damme E J; Briké F; Winter H C; Van Leuven F; Goldstein I J; Peumans W J
Molecular cloning of two different mannose-binding lectins from tulip bulbs.
European journal of biochemistry / FEBS 1996;236(2):419-27.
1996: Van Leuven F; Stas L; Hilliker C; Miyake Y; Bilinski P; Gossler A
Molecular cloning and characterization of the human interleukin-11 receptor alpha-chain gene, IL11RA, located on chromosome 9p13.
Genomics 1996;31(1):65-70.
1996: Van Damme E J; Barre A; Rougé P; Van Leuven F; Peumans W J
The NeuAc(alpha-2,6)-Gal/GalNAc-binding lectin from elderberry (Sambucus nigra) bark, a type-2 ribosome-inactivating protein with an unusual specificity and structure.
European journal of biochemistry / FEBS 1996;235(1-2):128-37.
1996: De Strooper B; Wu R R; Jaspers M; Van der Schueren B; Vekemans S; Carmeliet G; Van Leuven F; Van Den Oord J; Cassiman J J
A 68-kD antigen, which is probably an N-terminal fragment of the VLA-5 alpha 5-subunit, is specific for differentiating keratinocytes.
Dermatology (Basel, Switzerland) 1996;193(3):212-20.
1995: Van Damme E J; Barre A; Rougé P; Van Leuven F; Peumans W J
The seed lectins of black locust (Robinia pseudoacacia) are encoded by two genes which differ from the bark lectin genes.
Plant molecular biology 1995;29(6):1197-210.
1995: De Strooper B; Craessaerts K; Van Leuven F; Van Den Berghe H
Exchanging the extracellular domain of amyloid precursor protein for horseradish peroxidase does not interfere with alpha-secretase cleavage of the beta-amyloid region, but randomizes secretion in Madin-Darby canine kidney cells.
The Journal of biological chemistry 1995;270(51):30310-4.
1995: Van Damme E J; Barre A; Bemer V; Rougé P; Van Leuven F; Peumans W J
A lectin and a lectin-related protein are the two most prominent proteins in the bark of yellow wood (Cladrastis lutea).
Plant molecular biology 1995;29(3):579-98.
1995: Van Eynde A; Wera S; Beullens M; Torrekens S; Van Leuven F; Stalmans W; Bollen M
Molecular cloning of NIPP-1, a nuclear inhibitor of protein phosphatase-1, reveals homology with polypeptides involved in RNA processing.
The Journal of biological chemistry 1995;270(47):28068-74.
1995: Overbergh L; Lorent K; Torrekens S; Van Leuven F; Van den Berghe H
Expression of mouse alpha-macroglobulins, lipoprotein receptor-related protein, LDL receptor, apolipoprotein E, and lipoprotein lipase in pregnancy.
Journal of lipid research 1995;36(8):1774-86.
1995: Umans L; Serneels L; Overbergh L; Lorent K; Van Leuven F; Van den Berghe H
Targeted inactivation of the mouse alpha 2-macroglobulin gene.
The Journal of biological chemistry 1995;270(34):19778-85.
1995: Osborn R W; De Samblanx G W; Thevissen K; Goderis I; Torrekens S; Van Leuven F; Attenborough S; Rees S B; Broekaert W F
Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae.
FEBS letters 1995;368(2):257-62.
1995: Terras F R; Eggermont K; Kovaleva V; Raikhel N V; Osborn R W; Kester A; Rees S B; Torrekens S; Van Leuven F; Vanderleyden J
Small cysteine-rich antifungal proteins from radish: their role in host defense.
The Plant cell 1995;7(5):573-88.
1995: Van Damme E J; Goossens K; Smeets K; Van Leuven F; Verhaert P; Peumans W J
The major tuber storage protein of araceae species is a lectin. Characterization and molecular cloning of the lectin from Arum maculatum L.
Plant physiology 1995;107(4):1147-58.
1995: Spittaels K; Vankeerberghen A; Torrekens S; Devreese B; Grauwels L; Van Leuven F; Hunt D; Shabanowitz J; Schoofs L; Van Beeumen J
Isolation of Ala1-proctolin, the first natural analogue of proctolin, from the brain of the Colorado potato beetle.
Molecular and cellular endocrinology 1995;110(1-2):119-24.
1995: Lorent K; Overbergh L; Moechars D; De Strooper B; Van Leuven F; Van den Berghe H
Expression in mouse embryos and in adult mouse brain of three members of the amyloid precursor protein family, of the alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein and of its ligands apolipoprotein E, lipoprotein lipase, alpha-2-macroglobulin and the 40,000 molecular weight receptor-associated protein.
Neuroscience 1995;65(4):1009-25.
1995: Van Damme E J; Barre A; Smeets K; Torrekens S; Van Leuven F; Rougé P; Peumans W J
The bark of Robinia pseudoacacia contains a complex mixture of lectins. Characterization of the proteins and the cDNA clones.
Plant physiology 1995;107(3):833-43.
1995: De Strooper B; Craessaerts K; Dewachter I; Moechars D; Greenberg B; Van Leuven F; Van den Berghe H
Basolateral secretion of amyloid precursor protein in Madin-Darby canine kidney cells is disturbed by alterations of intracellular pH and by introducing a mutation associated with familial Alzheimer's disease.
The Journal of biological chemistry 1995;270(8):4058-65.
1995: De Strooper B; Creemers J W; Moechars D; Huylebroeck D; Van De Ven W J; Van Leuven F; Van den Berghe H
Amyloid precursor protein is not processed by furin, PACE 4, PC1/3, PC2, PC4 and PC5/6 of the furin family of proprotein processing enzymes.
Biochimica et biophysica acta 1995;1246(2):185-8.
1995: Van Leuven F; Hilliker C; Serneels L; Umans L; Overbergh L; De Strooper B; Fryns J P; Van den Berghe H
Cloning, characterization, and chromosomal localization to 4p16 of the human gene (LRPAP1) coding for the alpha 2-macroglobulin receptor-associated protein and structural comparison with the murine gene coding for the 44-kDa heparin-binding protein.
Genomics 1995;25(2):492-500.
1995: Spittaels K; Vankeerberghen A; Schoofs L; Torrekens S; Grauwels L; Van Leuven F; De Loof A
Identification, characterization, and immunological localization of a novel myotropic neuropeptide in the Colorado potato beetle, Leptinotarsa decemlineata.
Peptides 1995;16(3):365-74.
1994: Van Leuven F; Stas L; Hilliker C; Lorent K; Umans L; Serneels L; Overbergh L; Torrekens S; Moechars D; De Strooper B
Structure of the gene (LRP1) coding for the human alpha 2-macroglobulin receptor lipoprotein receptor-related protein.
Genomics 1994;24(1):78-89.
1994: Van Leuven F; Serneels L; Raymakers L; Hilliker C; Umans L
The human and mouse genes coding for the alpha 2MR-associated protein.
Annals of the New York Academy of Sciences 1994;737():504-5.
1994: Van Leuven F; Stas L; Raymakers L; Hilliker C
Structure of the human alpha 2M receptor gene.
Annals of the New York Academy of Sciences 1994;737():502-3.
1994: Umans L; Serneels L; Hilliker C; Van Leuven F
Structure and targeting in ES cells of the gene coding for mouse alpha 2-macroglobulin.
Annals of the New York Academy of Sciences 1994;737():500-1.
1994: Lorent K; Overbergh L; Van Leuven F
Expression of mouse alpha 2M and its receptor in vivo.
Annals of the New York Academy of Sciences 1994;737():498-9.
1994: Overbergh L; Lorent K; Hilliker C; Van Leuven F
Characterization of the genes coding for the murinoglobulins and expression in vivo.
Annals of the New York Academy of Sciences 1994;737():496-7.
1994: Van Leuven F; Umans L; Lorent K; Hilliker C; Serneels L; Overbergh L; Stas L; Raymakers L
Molecular analysis of the human and mouse alpha 2M family.
Annals of the New York Academy of Sciences 1994;737():163-71.
1994: Van Damme E J; Balzarini J; Smeets K; Van Leuven F; Peumans W J
The monomeric and dimeric mannose-binding proteins from the Orchidaceae species Listera ovata and Epipactis helleborine: sequence homologies and differences in biological activities.
Glycoconjugate journal 1994;11(4):321-32.
1994: Overbergh L; Hilliker C; Lorent K; Van Leuven F; Van den Berghe H
Identification of four genes coding for isoforms of murinoglobulin, the monomeric mouse alpha 2-macroglobulin: characterization of the exons coding for the bait region.
Genomics 1994;22(3):530-9.
1994: Umans L; Serneels L; Hilliker C; Stas L; Overbergh L; De Strooper B; Van Leuven F; Van den Berghe H
Molecular cloning of the mouse gene coding for alpha 2-macroglobulin and targeting of the gene in embryonic stem cells.
Genomics 1994;22(3):519-29.
1994: Van Damme J M; Smeets K; Torrekens S; Van Leuven F; Peumans W J
Characterization and molecular cloning of mannose-binding lectins from the Orchidaceae species Listera ovata, Epipactis helleborine and Cymbidium hybrid.
European journal of biochemistry / FEBS 1994;221(2):769-77.
1994: Van Damme E J; Smeets K; Van Leuven F; Peumans W J
Molecular cloning of mannose-binding lectins from Clivia miniata.
Plant molecular biology 1994;24(5):825-30.
1994: Lorent K; Overbergh L; Delabie J; Van Leuven F; Van den Berghe H
Distribution of mRNA coding for alpha-2-macroglobulin, the murinoglobulins, the alpha-2-macroglobulin receptor and the alpha-2-macroglobulin receptor associated protein during mouse embryogenesis and in adult tissues.
Differentiation; research in biological diversity 1994;55(3):213-23.
1994: Hilliker C; Delabie J; Speleman F; Bilbe G; Bruggen J; Van Leuven F; Van den Berghe H
Localization of the gene (RSN) coding for restin, a marker for Reed-Sternberg cells in Hodgkin's disease, to human chromosome band 12q24.3 and YAC cloning of the locus.
Cytogenetics and cell genetics 1994;65(3):172-6.
1993: Delabie J; Bilbe G; Brüggen J; Van Leuven F; De Wolf-Peeters C
Restin in Hodgkin's disease and anaplastic large cell lymphoma.
Leukemia & lymphoma 1993;12(1-2):21-6.
1993: Van Damme J M; Smeets K; Torrekens S; Van Leuven F; Peumans W J
The mannose-specific lectins from ramsons (Allium ursinum L.) are encoded by three sets of genes.
European journal of biochemistry / FEBS 1993;217(1):123-9.
1993: Van Damme E J; Smeets K; Engelborghs I; Aelbers H; Balzarini J; Pusztai A; van Leuven F; Goldstein I J; Peumans W J
Cloning and characterization of the lectin cDNA clones from onion, shallot and leek.
Plant molecular biology 1993;23(2):365-76.
1993: Jaspers M; Vekemans S; Carmeliet G; van Leuven F; de Strooper B; Deckmyn H; Cassiman J J
A monoclonal antibody to the alpha 2 integrin subunit cross-reacts with RGD-dependent epitopes in fibrinogen.
Hybridoma 1993;12(4):467-74.
1993: Van Leuven F; Torrekens S; Van den Berghe H
Isolation, characterization and partial sequencing of Pregnancy Associated Mouse Protein PAMP1 identifies it as a novel female specific protein, unrelated to the alpha-2-macroglobulin family of proteinase inhibitors.
FEBS letters 1993;322(3):219-22.
1993: Van Leuven F; Stas L; Raymakers L; Overbergh L; De Strooper B; Hilliker C; Lorent K; Fias E; Umans L; Torrekens S
Molecular cloning and sequencing of the murine alpha-2-macroglobulin receptor cDNA.
Biochimica et biophysica acta 1993;1173(1):71-4.
1993: De Strooper B; Umans L; Van Leuven F; Van Den Berghe H
Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): cleavage of APP occurs in a late compartment of the default secretion pathway.
The Journal of cell biology 1993;121(2):295-304.
1993: Terras F R; Torrekens S; Van Leuven F; Osborn R W; Vanderleyden J; Cammue B P; Broekaert W F
A new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.
FEBS letters 1993;316(3):233-40.
1992: Delabie J; Shipman R; Brüggen J; De Strooper B; van Leuven F; Tarcsay L; Cerletti N; Odink K; Diehl V; Bilbe G
Expression of the novel intermediate filament-associated protein restin in Hodgkin's disease and anaplastic large-cell lymphoma.
Blood 1992;80(11):2891-6.
1992: van Leuven F; Torrekens S; Overbergh L; Lorent K; de Strooper B; van den Berghe H
The primary sequence and the subunit structure of mouse alpha-2-macroglobulin, deduced from protein sequencing of the isolated subunits and from molecular cloning of the cDNA.
European journal of biochemistry / FEBS 1992;210(1):319-27.
1992: Van Damme E J; Smeets K; Torrekens S; Van Leuven F; Peumans W J
Isolation and characterization of alliinase cDNA clones from garlic (Allium sativum L.) and related species.
European journal of biochemistry / FEBS 1992;209(2):751-7.
1992: Terras F R; Schoofs H M; De Bolle M F; Van Leuven F; Rees S B; Vanderleyden J; Cammue B P; Broekaert W F
Analysis of two novel classes of plant antifungal proteins from radish (Raphanus sativus L.) seeds.
The Journal of biological chemistry 1992;267(22):15301-9.
1992: De Strooper B; Van Leuven F; Van den Berghe H
Alpha 2-macroglobulin and other proteinase inhibitors do not interfere with the secretion of amyloid precursor protein in mouse neuroblastoma cells.
FEBS letters 1992;308(1):50-3.
1992: Hilliker C; Van Leuven F; Van den Berghe H
Assignment of the gene coding for the alpha 2-macroglobulin receptor to mouse chromosome 15 and to human chromosome 12q13-q14 by isotopic and nonisotopic in situ hybridization.
Genomics 1992;13(2):472-4.
1992: van Damme E J; Smeets K; Torrekens S; van Leuven F; Goldstein I J; Peumans W J
The closely related homomeric and heterodimeric mannose-binding lectins from garlic are encoded by one-domain and two-domain lectin genes, respectively.
European journal of biochemistry / FEBS 1992;206(2):413-20.
1992: Hilliker C; Overbergh L; Petit P; Van Leuven F; Van den Berghe H
Assignment of mouse alpha-2-macroglobulin gene to chromosome 6 band F1-G3.
Mammalian genome : official journal of the International Mammalian Genome Society 1992;3(8):469-71.
1991: De Strooper B; Van Leuven F; Van den Berghe H
The amyloid beta protein precursor or proteinase nexin II from mouse is closer related to its human homolog than previously reported.
Biochimica et biophysica acta 1991;1129(1):141-3.
1991: Overbergh L; Torrekens S; Van Leuven F; Van den Berghe H
Molecular characterization of the murinoglobulins.
The Journal of biological chemistry 1991;266(25):16903-10.
1991: De Strooper B; Van Leuven F; Carmeliet G; Van Den Berghe H; Cassiman J J
Cultured human fibroblasts contain a large pool of precursor beta 1-integrin but lack an intracellular pool of mature subunit.
European journal of biochemistry / FEBS 1991;199(1):25-33.
1989: Devriendt K; Zhang J; van Leuven F; van den Berghe H; Cassiman J J; Marynen P
A cluster of alpha 2-macroglobulin-related genes (alpha 2 M) on human chromosome 12p: cloning of the pregnancy-zone protein gene and an alpha 2M pseudogene.
Gene 1989;81(2):325-34.
1989: De Strooper B; Van der Schueren B; Jaspers M; Saison M; Spaepen M; Van Leuven F; Van den Berghe H; Cassiman J J
Distribution of the beta 1 subgroup of the integrins in human cells and tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1989;37(3):299-307.
1988: Van Leuven F; Marynen P; Cassiman J J; Van den Berghe H
Mapping of structure-function relationships in proteins with a panel of monoclonal antibodies. A study on human alpha 2 macroglobulin.
Journal of immunological methods 1988;111(1):39-49.
1988: Jaspers M; de Strooper B; Spaepen M; van Leuven F; David G; van den Berghe H; Cassiman J J
Post-translational modification of the beta-subunit of the human fibronectin receptor.
FEBS letters 1988;231(2):402-6.
1988: De Strooper B; Saison M; Jaspers M; Spaepen M; Van Leuven F; Van den Berghe H; Cassiman J J
Monoclonal antibody DH12 reacts with a cell surface and a precursor form of the beta subunit of the human fibronectin receptor.
Cell biology international reports 1988;12(1):9-16.
1988: Zhang Y; Saison M; Spaepen M; De Strooper B; Van Leuven F; David G; Van den Berghe H; Cassiman J J
Mapping of human fibronectin receptor beta subunit gene to chromosome 10.
Somatic cell and molecular genetics 1988;14(1):99-104.
1988: Van Leuven F; Marynen P; Cassiman J J; Van den Berghe H
Proteolysis of human alpha 2-macroglobulin without hydrolysis of the internal thiolesters or expression of the receptor recognition site.
The Journal of biological chemistry 1988;263(1):468-71.
1987: Van Leuven F; Marynen P; Cassiman J J; Van den Berghe H
A mouse monoclonal antibody to human alpha 2-macroglobulin (alpha 2M) crossreacts with alpha 2M from mouse: epitope mapping and characterization of subunit structure of murine alpha 2M.
Journal of biochemistry 1987;101(5):1181-9.
1983: Saison M; Verlinden J; Van Leuven F; Cassiman J J; Van den Berghe H
Identification of cell surface dipeptidylpeptidase IV in human fibroblasts.
The Biochemical journal 1983;216(1):177-83.
1981: Van Leuven F; Marynen P; Cassiman J J; Van den Berghe H
Receptor-mediated endocytosis of alpha 2macroglobulin-protease complexes by fibroblasts in culture. Competitive inhibition by bacitracin.
FEBS letters 1981;134(1):83-7.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Fred Van Leuven

Research Profile (preview)

Living Beings

Concepts & Ideas

Genes & Molecular Sequences

Chemicals & Drugs

Procedures

Disorders

Anatomy

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Fred Van Leuven (preview)

All Publications