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Daniel Bout

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Marie-Noëlle Mévélec; Céline Ducournau; Alaa Bassuny Ismael; Michel Olivier; Edouard Sèche; Maryse Lebrun; Daniel Bout; Isabelle Dimier-Poisson
Mic1-3 Knockout Toxoplasma gondii is a good candidate for a vaccine against T. gondii-induced abortion in sheep.
Céline Beauvillain; Sophie Ruiz; Rachel Guiton; Daniel Bout; Isabelle Dimier-Poisson
A vaccine based on exosomes secreted by a dendritic cell line confers protection against T. gondii infection in syngeneic and allogeneic mice.
Marc Clastre; Armelle Goubard; Anne Prel; Zoia Mincheva; Marie-Claude Viaud-Massuart; Daniel Bout; Marc Rideau; Florence Velge-Roussel; Fabrice Laurent
The methylerythritol phosphate pathway for isoprenoid biosynthesis in coccidia: presence and sensitivity to fosmidomycin.

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All Publications

2010: Marie-Noëlle Mévélec; Céline Ducournau; Alaa Bassuny Ismael; Michel Olivier; Edouard Sèche; Maryse Lebrun; Daniel Bout; Isabelle Dimier-Poisson
Mic1-3 Knockout Toxoplasma gondii is a good candidate for a vaccine against T. gondii-induced abortion in sheep.
Veterinary research 2010;41(4):49.
2007: Céline Beauvillain; Sophie Ruiz; Rachel Guiton; Daniel Bout; Isabelle Dimier-Poisson
A vaccine based on exosomes secreted by a dendritic cell line confers protection against T. gondii infection in syngeneic and allogeneic mice.
Microbes and infection / Institut Pasteur 2007;9(14-15):1614-22.
2007: Marc Clastre; Armelle Goubard; Anne Prel; Zoia Mincheva; Marie-Claude Viaud-Massuart; Daniel Bout; Marc Rideau; Florence Velge-Roussel; Fabrice Laurent
The methylerythritol phosphate pathway for isoprenoid biosynthesis in coccidia: presence and sensitivity to fosmidomycin.
Experimental parasitology 2007;116(4):375-84.
2007: Fleur Aline; Denys Brand; Daniel Bout; Josette Pierre; Delphine Fouquenet; Bernard Verrier; Isabelle Dimier-Poisson
Generation of specific Th1 and CD8+ T-cell responses by immunization with mouse CD8+ dendritic cells loaded with HIV-1 viral lysate or envelope glycoproteins.
Microbes and infection / Institut Pasteur 2007;9(4):536-43.
2006: Alaa Bassuny ISMAEL; Isabelle Dimier-Poisson; Maryse Lebrun; Jean-François Dubremetz; Daniel Bout; Marie-Noëlle Mevelec
Mic1-3 knockout of Toxoplasma gondii is a successful vaccine against chronic and congenital toxoplasmosis in mice.
The Journal of infectious diseases 2006;194(8):1176-83.
2006: Isabelle Dimier-Poisson; Fleur Aline; Daniel Bout; Marie-Noëlle Mévélec
Induction of protective immunity against toxoplasmosis in mice by immunization with Toxoplasma gondii RNA.
Vaccine 2006;24(10):1705-9.
2005: Sophie Ruiz; Céline Beauvillain; Marie-Noëlle Mévélec; Philippe Roingeard; Pascal Breton; Daniel Bout; Isabelle Dimier-Poisson
A novel CD4-CD8alpha+CD205+CD11b- murine spleen dendritic cell line: establishment, characterization and functional analysis in a model of vaccination to toxoplasmosis.
Cellular microbiology 2005;7(11):1659-71.
2005: Marie-Noëlle Mévélec; Daniel Bout; Benoît Desolme; Hervé Marchand; Rémy Magné; Odile Bruneel; Dominique Buzoni-Gatel
Evaluation of protective effect of DNA vaccination with genes encoding antigens GRA4 and SAG1 associated with GM-CSF plasmid, against acute, chronical and congenital toxoplasmosis in mice.
Vaccine 2005;23(36):4489-99.
2005: Odile Cérède; Jean-François Dubremetz; Martine Soête; Didier Deslée; Henri VIAL; Daniel Bout; Maryse Lebrun
Synergistic role of micronemal proteins in Toxoplasma gondii virulence.
The Journal of experimental medicine 2005;201(3):453-63.
2004: Isabelle Dimier-Poisson; Daniel Bout; P Quéré
Chicken primary enterocytes: inhibition of Eimeria tenella replication after activation with crude interferon-gamma supernatants.
Avian diseases 2004;48(3):617-24.
2004: Mathieu-Benoît Voisin; Dominique Buzoni-Gatel; Daniel Bout; Florence Velge-Roussel
Both expansion of regulatory GR1+ CD11b+ myeloid cells and anergy of T lymphocytes participate in hyporesponsiveness of the lung-associated immune system during acute toxoplasmosis.
Infection and immunity 2004;72(9):5487-92.
2004: Fleur Aline; Daniel Bout; Sébastian Amigorena; Philippe Roingeard; Isabelle Dimier-Poisson
Toxoplasma gondii antigen-pulsed-dendritic cell-derived exosomes induce a protective immune response against T. gondii infection.
Infection and immunity 2004;72(7):4127-37.
2003: Alaa Bassuny ISMAEL; Dalila Sekkai; Christine Collin; Daniel Bout; Marie-Noëlle Mévélec
The MIC3 gene of Toxoplasma gondii is a novel potent vaccine candidate against toxoplasmosis.
Infection and immunity 2003;71(11):6222-8.
2003: Isabelle Dimier-Poisson; Fleur Aline; Marie-Noëlle Mévélec; Céline Beauvillain; Dominique Buzoni-Gatel; Daniel Bout
Protective mucosal Th2 immune response against Toxoplasma gondii by murine mesenteric lymph node dendritic cells.
Infection and immunity 2003;71(9):5254-65.
2003: Daniel Bout; Marie-Noëlle Mévélec; Florence Velge-Roussel; Isabelle Dimier-Poisson; Maryse Lebrun
[Vaccines on mucosal surfaces].
Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie 2003;10(6):565-70.
2002: Daniel Bout; Marie-Noëlle Mevelec; Florence Velge-Roussel; Isabelle Dimier-Poisson; Maryse Lebrun
Prospects for a human Toxoplasma vaccine.
Current drug targets. Immune, endocrine and metabolic disorders 2002;2(3):227-34.
2002: Odile Cérède; Jean-François Dubremetz; Daniel Bout; Maryse Lebrun
The Toxoplasma gondii protein MIC3 requires pro-peptide cleavage and dimerization to function as adhesin.
The EMBO journal 2002;21(11):2526-36.
2002: Fleur Aline; Daniel Bout; Isabelle Dimier-Poisson
Dendritic cells as effector cells: gamma interferon activation of murine dendritic cells triggers oxygen-dependent inhibition of Toxoplasma gondii replication.
Infection and immunity 2002;70(5):2368-74.
2002: Philippe Velge; Elisabeth Bottreau; Pascale Quéré; Pierre Pardon; Jean Claude Nicolle; Mireille Morisson; Daniel Bout; Isabelle Dimier
Establishment and characterization of partially differentiated chicken enterocyte cell clones.
European journal of cell biology 2002;81(4):203-12.
2001: Odile Cérède; N Garcia-Réguet; V Conseil; Daniel Bout; Jean-François Dubremetz; Maryse Lebrun
[Identification and molecular characterization of a Toxoplasma gondii microneme].
Annales pharmaceutiques françaises 2001;59(5):293-6.
2001: Florence Velge-Roussel; Isabelle Dimier-Poisson; Dominique Buzoni-Gatel; Daniel Bout
Anti-SAG1 peptide antibodies inhibit the penetration of Toxoplasma gondii tachyzoites into enterocyte cell lines.
Parasitology 2001;123(Pt 3):225-33.
2001: C Bonenfant; Isabelle Dimier-Poisson; Florence Velge-Roussel; Dominique Buzoni-Gatel; G Del Giudice; R Rappuoli; Daniel Bout
Intranasal immunization with SAG1 and nontoxic mutant heat-labile enterotoxins protects mice against Toxoplasma gondii.
Infection and immunity 2001;69(3):1605-12.
2000: N Garcia-Réguet; Maryse Lebrun; Marie Noëlle Fourmaux; Odile Mercereau-Puijalon; T Mann; Cornelis Beckers; Bart Samyn; J Van Beeumen; Daniel Bout; Jean-François Dubremetz
The microneme protein MIC3 of Toxoplasma gondii is a secretory adhesin that binds to both the surface of the host cells and the surface of the parasite.
Cellular microbiology 2000;2(4):353-64.
2000: B Desolme; Marie-Noëlle Mévélec; Dominique Buzoni-Gatel; Daniel Bout
Induction of protective immunity against toxoplasmosis in mice by DNA immunization with a plasmid encoding Toxoplasma gondii GRA4 gene.
Vaccine 2000;18(23):2512-21.
2000: Florence Velge-Roussel; P Marcelo; AC Lepage; Dominique Buzoni-Gatel; Daniel Bout
Intranasal immunization with Toxoplasma gondii SAG1 induces protective cells into both NALT and GALT compartments.
Infection and immunity 2000;68(2):969-72.
1999: Daniel Bout; magali moretto; Isabelle Dimier-Poisson; D B Gatel
Interaction between Toxoplasma gondii and enterocyte.
Immunobiology 1999;201(2):225-8.
1999: C Dupuy; Dominique Buzoni-Gatel; Antoine Touzé; Daniel Bout; Pierre Coursaget
Nasal immunization of mice with human papillomavirus type 16 (HPV-16) virus-like particles or with the HPV-16 L1 gene elicits specific cytotoxic T lymphocytes in vaginal draining lymph nodes.
Journal of virology 1999;73(11):9063-71.
1999: S Sagodira; S Iochmann; Marie-Noëlle Mevelec; Isabelle Dimier-Poisson; Daniel Bout
Nasal immunization of mice with Cryptosporidium parvum DNA induces systemic and intestinal immune responses.
Parasite immunology 1999;21(10):507-16.
1999: S Iochmann; S Sagodira; Marie-Noëlle Mévélec; J M Répérant; M Naciri; Pierre Coursaget; Daniel Bout
Comparison of the humoral and cellular immune responses to two preparations of Cryptosporidium parvum CP15/60 recombinant protein.
Microbial pathogenesis 1999;26(6):307-15.
1999: Dominique Buzoni-Gatel; Hajer Debbabi; magali moretto; Isabelle Dimier-Poisson; AC Lepage; Daniel Bout; Lloyd H Kasper
Intraepithelial lymphocytes traffic to the intestine and enhance resistance to Toxoplasma gondii oral infection.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(10):5846-52.
1999: S Sagodira; Dominique Buzoni-Gatel; S Iochmann; M Naciri; Daniel Bout
Protection of kids against Cryptosporidium parvum infection after immunization of dams with CP15-DNA.
Vaccine 1999;17(19):2346-55.
1999: Z Fermin; Daniel Bout; P Ricciardi-Castagnoli; Johan Hoebeke
Salbutamol as an adjuvant for nasal vaccination.
Vaccine 1999;17(15-16):1936-41.
1999: Isabelle Dimier-Poisson; Z Soundouss; Muriel Naciri; Daniel Bout; P Quéré
Mechanisms of the Eimeria tenella growth inhibitory activity induced by concanavalin A and reticuloendotheliosis virus supernatants with interferon gamma activity in chicken macrophages and fibroblasts.
Avian diseases 1999;43(1):65-74.
1998: AC Lepage; Dominique Buzoni-Gatel; Daniel Bout; Lloyd H Kasper
Gut-derived intraepithelial lymphocytes induce long term immunity against Toxoplasma gondii.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(9):4902-8.
1998: I Bourguin; M Moser; Dominique Buzoni-Gatel; F Tielemans; Daniel Bout; J Urbain; Oberdan Leo
Murine dendritic cells pulsed in vitro with Toxoplasma gondii antigens induce protective immunity in vivo.
Infection and immunity 1998;66(10):4867-74.
1998: Isabelle Dimier; Daniel Bout
Interferon-gamma-activated primary enterocytes inhibit Toxoplasma gondii replication: a role for intracellular iron.
Immunology 1998;94(4):488-95.
1998: Isabelle Dimier; P Quéré; Muriel Naciri; Daniel Bout
Inhibition of Eimeria tenella development in vitro mediated by chicken macrophages and fibroblasts treated with chicken cell supernatants with IFN-gamma activity.
Avian diseases 1998;42(2):239-47.
1998: Marie-Noëlle Mévélec; Odile Mercereau-Puijalon; Dominique Buzoni-Gatel; I Bourguin; T Chardès; Jean-François Dubremetz; Daniel Bout
Mapping of B epitopes in GRA4, a dense granule antigen of Toxoplasma gondii and protection studies using recombinant proteins administered by the oral route.
Parasite immunology 1998;20(4):183-95.
1997: Florence Velge-Roussel; magali moretto; Dominique Buzoni-Gatel; Isabelle Dimier-Poisson; M Ferrer; J Hoebeke; Daniel Bout
Differences in immunological response to a T. gondii protein (SAG1) derived peptide between two strains of mice: effect on protection in T. gondii infection.
Molecular immunology 1997;34(15):1045-53.
1997: Isabelle Dimier; Daniel Bout
Inhibition of Toxoplasma gondii replication in IFN-gamma-activated human intestinal epithelial cells.
Immunology and cell biology 1997;75(5):511-4.
1997: Dominique Buzoni-Gatel; AC Lepage; Isabelle Dimier-Poisson; Daniel Bout; Lloyd H Kasper
Adoptive transfer of gut intraepithelial lymphocytes protects against murine infection with Toxoplasma gondii.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(12):5883-9.
1997: C Dupuy; Dominique Buzoni-Gatel; A Touze; P Le Cann; Daniel Bout; Pierre Coursaget
Cell mediated immunity induced in mice by HPV 16 L1 virus-like particles.
Microbial pathogenesis 1997;22(4):219-25.
1996: Florence Velge-Roussel; Pascal Breton; X Guillon; F Lescure; N Bru; Daniel Bout; J Hoebeke
Immunochemical characterization of antibody-coated nanoparticles.
Experientia 1996;52(8):803-6.
1996: N Debard; Dominique Buzoni-Gatel; Daniel Bout
Intranasal immunization with SAG1 protein of Toxoplasma gondii in association with cholera toxin dramatically reduces development of cerebral cysts after oral infection.
Infection and immunity 1996;64(6):2158-66.
1996: Isabelle Dimier; Daniel Bout
Inhibitory effect of interferon-gamma activated ovine umbilical vein endothelial cells on the intracellular replication of Toxoplasma gondii.
Veterinary research 1996;27(4-5):527-34.
1995: I Bourguin; T Chardès; Daniel Bout
Peritoneal macrophages from C57BL/6 mice orally immunized with Toxoplasma gondii antigens in association with cholera toxin possess an enhanced ability to inhibit parasite multiplication.
FEMS immunology and medical microbiology 1995;12(2):121-6.
1995: Florence Velge-Roussel; Pascal Breton; F Lescure; X Guillon; Daniel Bout; J Hoebeke
Analysis of human CD4-antibody interaction using the BIAcore system.
Journal of immunological methods 1995;183(1):141-8.
1995: Daniel Bout; Dominique Buzoni-Gatel; T Chardès; N Debard; M N Mevelec
Mucosal vaccination against toxoplasmosis.
Veterinary research 1995;26(3):214-5.
1994: T Chardès; Dominique Buzoni-Gatel; AC Lepage; F Bernard; Daniel Bout
Toxoplasma gondii oral infection induces specific cytotoxic CD8 alpha/beta+ Thy-1+ gut intraepithelial lymphocytes, lytic for parasite-infected enterocytes.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(10):4596-603.
1994: J M Répérant; Muriel Naciri; S Iochmann; M Tilley; Daniel Bout
Major antigens of Cryptosporidium parvum recognised by serum antibodies from different infected animal species and man.
Veterinary parasitology 1994;55(1-2):1-13.
1994: Florence Velge-Roussel; T Chardès; P Mévélec; M Brillard; J Hoebeke; Daniel Bout
Epitopic analysis of the Toxoplasma gondii major surface antigen SAG1.
Molecular and biochemical parasitology 1994;66(1):31-8.
1993: Isabelle Dimier; Daniel Bout
Co-operation of interleukin-1 beta and tumour necrosis factor-alpha in the activation of human umbilical vein endothelial cells to inhibit Toxoplasma gondii replication.
Immunology 1993;79(2):336-8.
1993: I Bourguin; T Chardès; Daniel Bout
Oral immunization with Toxoplasma gondii antigens in association with cholera toxin induces enhanced protective and cell-mediated immunity in C57BL/6 mice.
Infection and immunity 1993;61(5):2082-8.
1993: Isabelle Dimier; Daniel Bout
Rat intestinal epithelial cell line IEC-6 is activated by recombinant interferon-gamma to inhibit replication of the coccidian Toxoplasma gondii.
European journal of immunology 1993;23(4):981-3.
1993: T Chardès; Florence Velge-Roussel; P Mevelec; M N Mevelec; Dominique Buzoni-Gatel; Daniel Bout
Mucosal and systemic cellular immune responses induced by Toxoplasma gondii antigens in cyst orally infected mice.
Immunology 1993;78(3):421-9.
1993: T Chardès; Daniel Bout
Mucosal immune response in toxoplasmosis.
Research in immunology 1993;144(1):57-60.
1992: M N Mevelec; T Chardès; Odile Mercereau-Puijalon; I Bourguin; A Achbarou; Jean-François Dubremetz; Daniel Bout
Molecular cloning of GRA4, a Toxoplasma gondii dense granule protein, recognized by mucosal IgA antibodies.
Molecular and biochemical parasitology 1992;56(2):227-38.
1992: J M Reperant; Muriel Naciri; T Chardes; Daniel Bout
Immunological characterization of a 17-kDa antigen from Cryptosporidium parvum recognized early by mucosal IgA antibodies.
FEMS microbiology letters 1992;78(1):7-14.
1992: Isabelle Dimier; J P Woodman; Daniel Bout
[Human endothelial cells activated by interferon gamma, by interleukin-1 and TNF inhibit the replication of Toxoplasma gondii].
Annales de recherches vétérinaires. Annals of veterinary research 1992;23(3):329-30.
1992: T Chardès; Florence Velge-Roussel; M N Mevelec; F Blaise; Daniel Bout
Local and systemic cellular immunity following oral infection of mice with Toxoplasma gondii cysts.
Annales de recherches vétérinaires. Annals of veterinary research 1992;23(3):290-1.
1992: Florence Velge-Roussel; T Chardès; P Mevelec; Daniel Bout
Cellular and humoral recognition of Toxoplasma gondii P30 antigen and its cleavage fragments.
Annales de recherches vétérinaires. Annals of veterinary research 1992;23(3):291-2.
1991: J P Woodman; Isabelle Dimier; Daniel Bout
Human endothelial cells are activated by IFN-gamma to inhibit Toxoplasma gondii replication. Inhibition is due to a different mechanism from that existing in mouse macrophages and human fibroblasts.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(6):2019-23.
1991: I Bourguin; T Chardes; M N Mevelec; J P Woodman; Daniel Bout
Amplification of the secretory IgA response to Toxoplasma gondii using cholera toxin.
FEMS microbiology letters 1991;65(3):265-71.
1990: T Chardès; I Bourguin; M N Mevelec; Jean-François Dubremetz; Daniel Bout
Antibody responses to Toxoplasma gondii in sera, intestinal secretions, and milk from orally infected mice and characterization of target antigens.
Infection and immunity 1990;58(5):1240-6.