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Jan van Maanen

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TOP 3
Ingrid T M Vermeer; Laila Y Henderson; Edwin J C Moonen; Leopold G J B Engels; Jan W Dallinga; Jan M S van Maanen; Jos C S Kleinjans
Neutrophil-mediated formation of carcinogenic N-nitroso compounds in an in vitro model for intestinal inflammation.
Jacob J Briedé; Roger Godschalk; Marijn T G Emans; Theo M C M De Kok; Ebienus van Agen; Jan M S van Maanen; Frederik J Van Schooten; Jos C S Kleinjans
In vitro and in vivo studies on oxygen free radical and DNA adduct formation in rat lung and liver during benzo[a]pyrene metabolism.
Jos C S Kleinjans; Marcel H M van Herwijnen; Jan M S van Maanen; Lou M Maas; Theo M C M De Kok; Harald J J Moonen; Jacob J Briedé
In vitro investigations into the interaction of beta-carotene with DNA: evidence for the role of carbon-centered free radicals.

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All Publications

2004: Ingrid T M Vermeer; Laila Y Henderson; Edwin J C Moonen; Leopold G J B Engels; Jan W Dallinga; Jan M S van Maanen; Jos C S Kleinjans
Neutrophil-mediated formation of carcinogenic N-nitroso compounds in an in vitro model for intestinal inflammation.
Toxicology letters 2004;154(3):175-82.
2004: Jacob J Briedé; Roger Godschalk; Marijn T G Emans; Theo M C M De Kok; Ebienus van Agen; Jan M S van Maanen; Frederik J Van Schooten; Jos C S Kleinjans
In vitro and in vivo studies on oxygen free radical and DNA adduct formation in rat lung and liver during benzo[a]pyrene metabolism.
Free radical research 2004;38(9):995-1002.
2004: Jos C S Kleinjans; Marcel H M van Herwijnen; Jan M S van Maanen; Lou M Maas; Theo M C M De Kok; Harald J J Moonen; Jacob J Briedé
In vitro investigations into the interaction of beta-carotene with DNA: evidence for the role of carbon-centered free radicals.
Carcinogenesis 2004;25(7):1249-56.
2002: Harald J J Moonen; Jacob J Briedé; Jan M S van Maanen; Jos C S Kleinjans; Theo M C M De Kok
Generation of free radicals and induction of DNA adducts by activation of heterocyclic aromatic amines via different metabolic pathways in vitro.
Molecular carcinogenesis 2002;35(4):196-203.
2002: Ingrid T M Vermeer; M M Gerrits; Edwin J C Moonen; Leopold G J B Engels; Jan W Dallinga; Jos C S Kleinjans; Jan M S van Maanen; Ernst J Kuipers; Johannes G Kusters
Helicobacter pylori does not mediate the formation of carcinogenic N-nitrosamines.
Helicobacter 2002;7(3):163-9.
2001: Jan M S van Maanen; M A De Vaan; A W Veldstra; W P Hendrix
Pesticides and nitrate in groundwater and rainwater in the Province of Limburg in The Netherlands.
Environmental monitoring and assessment 2001;72(1):95-114.
2001: Ingrid T M Vermeer; Leopold G J B Engels; Daniëlle M F A Pachen; Jan W Dallinga; Jos C S Kleinjans; Jan M S van Maanen
Intragastric volatile N-nitrosamines, nitrite, pH, and Helicobacter pylori during long-term treatment with omeprazole.
Gastroenterology 2001;121(3):517-25.
2001: Ingrid T M Vermeer; Jan M S van Maanen
Nitrate exposure and the endogenous formation of carcinogenic nitrosamines in humans.
Reviews on environmental health 2001;16(2):105-16.
2000: Patrick Levallois; Pierre Ayotte; Jan M S van Maanen; Thérèse Desrosiers; S Gingras; Jan W Dallinga; Ingrid T M Vermeer; John Zee; G Poirier
Excretion of volatile nitrosamines in a rural population in relation to food and drinking water consumption.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2000;38(11):1013-9.
2000: Theo M C M De Kok; Jan M S van Maanen
Evaluation of fecal mutagenicity and colorectal cancer risk.
Mutation research 2000;463(1):53-101.
2000: Jan M S van Maanen; Harma Albering; Theo M C M De Kok; Simone G J van Breda; Daniëlle M J Curfs; Ingrid T M Vermeer; Anton W Ambergen; Bruce Wolffenbuttel; Jos C S Kleinjans; H M Reeser
Does the risk of childhood diabetes mellitus require revision of the guideline values for nitrate in drinking water?
Environmental health perspectives 2000;108(5):457-61.
1999: Jan M S van Maanen; Paul J A Borm; Ad M Knaapen; Marcel H M van Herwijnen; P A E L Schilderman; K R Smith; A E Aust; Maura Tomatis; Bice Fubini
In vitro effects of coal fly ashes: hydroxyl radical generation, iron release, and DNA damage and toxicity in rat lung epithelial cells.
Inhalation toxicology 1999;11(12):1123-41.
1999: Jan M S van Maanen; Harma Albering; Simone G J van Breda; Daniëlle M J Curfs; Anton W Ambergen; Bruce Wolffenbuttel; J C Kleinjans; H M Reeser
Nitrate in drinking water and risk of childhood diabetes in The Netherlands.
Diabetes care 1999;22(10):1750.
1999: Ingrid T M Vermeer; Edwin J C Moonen; Jan W Dallinga; Jos C S Kleinjans; Jan M S van Maanen
Effect of ascorbic acid and green tea on endogenous formation of N-nitrosodimethylamine and N-nitrosopiperidine in humans.
Mutation research 1999;428(1-2):353-61.
1998: Ingrid T M Vermeer; Daniëlle M F A Pachen; Jan W Dallinga; Jos C S Kleinjans; Jan M S van Maanen
Volatile N-nitrosamine formation after intake of nitrate at the ADI level in combination with an amine-rich diet.
Environmental health perspectives 1998;106(8):459-63.
1998: Jan W Dallinga; Daniëlle M F A Pachen; A H Lousberg; J A van Geel; G M Houben; Reinhold W Stockbrügger; Jan M S van Maanen; Jos C S Kleinjans
Volatile N-nitrosamines in gastric juice of patients with various conditions of the gastrointestinal tract determined by gas chromatography-mass spectrometry and related to intragastric pH and nitrate and nitrite levels.
Cancer letters 1998;124(2):119-25.
1998: Jan M S van Maanen; Daniëlle M F A Pachen; Jan W Dallinga; Jos C S Kleinjans
Formation of nitrosamines during consumption of nitrate- and amine-rich foods, and the influence of the use of mouthwashes.
Cancer detection and prevention 1998;22(3):204-12.
1996: Jan M S van Maanen; Jan W Dallinga; Jos C S Kleinjans
Environmental exposure to N-nitroso compounds and their precursors.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 1996;5 Suppl 1():29-31.
1996: Jan M S van Maanen; I J Welle; GJ Hageman; Jan W Dallinga; Paul L J M Mertens; Jos C S Kleinjans
Nitrate contamination of drinking water: relationship with HPRT variant frequency in lymphocyte DNA and urinary excretion of N-nitrosamines.
Environmental health perspectives 1996;104(5):522-8.
1996: Jan M S van Maanen; A A van Geel; Jos C S Kleinjans
Modulation of nitrate-nitrite conversion in the oral cavity.
Cancer detection and prevention 1996;20(6):590-6.
1994: T M de Kok; Daniëlle M F A Pachen; Jan M S van Maanen; M Vincent M Lafleur; E J Westmijze; F ten Hoor; Jos C S Kleinjans
Role of oxidative DNA damage in the mechanism of fecapentaene-12 genotoxicity.
Carcinogenesis 1994;15(11):2559-65.
1994: Jan M S van Maanen; Edwin J C Moonen; Lou M Maas; Jos C S Kleinjans; Frederik J Van Schooten
Formation of aromatic DNA adducts in white blood cells in relation to urinary excretion of 1-hydroxypyrene during consumption of grilled meat.
Carcinogenesis 1994;15(10):2263-8.
1994: T M de Kok; F ten Vaarwerk; I Zwingman; Jan M S van Maanen; Jos C S Kleinjans
Peroxidation of linoleic, arachidonic and oleic acid in relation to the induction of oxidative DNA damage and cytogenetic effects.
Carcinogenesis 1994;15(7):1399-404.
1994: Jan M S van Maanen; A van Dijk; K Mulder; marc de baets; P C Menheere; D van der Heide; Paul L J M Mertens; Jos C S Kleinjans
Consumption of drinking water with high nitrate levels causes hypertrophy of the thyroid.
Toxicology letters 1994;72(1-3):365-74.
1994: Jan M S van Maanen; Lou M Maas; GJ Hageman; Jos C S Kleinjans; B van Agen
DNA adduct and mutation analysis in white blood cells of smokers and nonsmokers.
Environmental and molecular mutagenesis 1994;24(1):46-50.
1993: P A E L Schilderman; Jan M S van Maanen; F J ten Vaarwerk; M Vincent M Lafleur; E J Westmijze; F ten Hoor; Jos C S Kleinjans
The role of prostaglandin H synthase-mediated metabolism in the induction of oxidative DNA damage by BHA metabolites.
Carcinogenesis 1993;14(7):1297-302.
1993: P A E L Schilderman; Jan M S van Maanen; E J Smeets; F ten Hoor; Jos C S Kleinjans
Oxygen radical formation during prostaglandin H synthase-mediated biotransformation of butylated hydroxyanisole.
Carcinogenesis 1993;14(3):347-53.
1993: Jos C S Kleinjans; Jan M S van Maanen; Frederik J Van Schooten
Human respiratory disease: environmental carcinogens and lung cancer risk.
Ciba Foundation symposium 1993;175():171-8; discussion 178-81.
1992: T M de Kok; Jan M S van Maanen; Jan Lankelma; F ten Hoor; Jos C S Kleinjans
Electron spin resonance spectroscopy of oxygen radicals generated by synthetic fecapentaene-12 and reduction of fecapentaene mutagenicity to Salmonella typhimurium by hydroxyl radical scavenging.
Carcinogenesis 1992;13(7):1249-55.
1991: D R Mans; M Vincent M Lafleur; E J Westmijze; Jan M S van Maanen; M A van Schaik; Jan Lankelma; J Retèl
Formation of different reaction products with single- and double-stranded DNA by the ortho-quinone and the semi-quinone free radical of etoposide (VP-16-213).
Biochemical pharmacology 1991;42(11):2131-9.
1991: Jos C S Kleinjans; Harma Albering; A Marx; Jan M S van Maanen; B van Agen; F ten Hoor; G M Swaen; Paul L J M Mertens
Nitrate contamination of drinking water: evaluation of genotoxic risk in human populations.
Environmental health perspectives 1991;94():189-93.
1990: D R Mans; J Retèl; Jan M S van Maanen; M Vincent M Lafleur; M A van Schaik; HERBERT PINEDO; Jan Lankelma
Role of the semi-quinone free radical of the anti-tumour agent etoposide (VP-16-213) in the inactivation of single- and double-stranded phi X174 DNA.
British journal of cancer 1990;62(1):54-60.
1990: Jan M S van Maanen; D R Mans; M Vincent M Lafleur; M A Van Schaik; J de Vries; N P Vermeulen; J Retèl; Jan Lankelma
Effects of oxygen radical scavengers on the inactivation of SS phi X174 DNA by the semi-quinone free radical of the antitumor agent etoposide.
Free radical research communications 1990;9(2):69-86.
1988: Jan M S van Maanen; J Retèl; J de Vries; HERBERT PINEDO
Mechanism of action of antitumor drug etoposide: a review.
Journal of the National Cancer Institute 1988;80(19):1526-33.
1988: Jan M S van Maanen; M Vincent M Lafleur; D R Mans; E van den Akker; C de Ruiter; P R Kootstra; D Pappie; J de Vries; J Retèl; HERBERT PINEDO
Effects of the ortho-quinone and catechol of the antitumor drug VP-16-213 on the biological activity of single-stranded and double-stranded phi X174 DNA.
Biochemical pharmacology 1988;37(19):3579-89.
1988: Jan M S van Maanen; E van den Akker; J de Vries; T R Bakkenist; Jan Lankelma; J Retèl; HERBERT PINEDO
Structure-bioactivation relationship of a series of podophyllotoxin derivatives.
European journal of cancer & clinical oncology 1988;24(9):1415-9.
1988: Jan M S van Maanen; U H Verkerk; J Broersen; M Vincent M Lafleur; J De Vries; J Retèl; HERBERT PINEDO
Semi-quinone formation from the catechol and ortho-quinone metabolites of the antitumor agent VP-16-213.
Free radical research communications 1988;4(6):371-84.
1987: Jan M S van Maanen; J de Vries; D Pappie; E van den Akker; V M Lafleur; J Retèl; J van der Greef; HERBERT PINEDO
Cytochrome P-450-mediated O-demethylation: a route in the metabolic activation of etoposide (VP-16-213).
Cancer research 1987;47(17):4658-62.
1986: Jan M S van Maanen; C De Ruiter; P R Kootstra; J De Vries; HERBERT PINEDO
Free radical formation from the antineoplastic agent VP 16-213.
Free radical research communications 1986;1(4):263-72.
1985: Jan M S van Maanen; C de Ruiter; P R Kootstra; M Vincent M Lafleur; J de Vries; J Retèl; HERBERT PINEDO
Inactivation of phi X174 DNA by the ortho-quinone derivative or its reduction product of the antitumor agent VP 16-213.
European journal of cancer & clinical oncology 1985;21(10):1215-8.
1985: Jan M S van Maanen; C de Ruiter; J de Vries; P R Kootstra; F Gobas; HERBERT PINEDO
The role of metabolic activation by cytochrome P-450 in covalent binding of VP 16-213 to rat liver and HeLa cell microsomal proteins.
European journal of cancer & clinical oncology 1985;21(9):1099-106.