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Ellen Van Obberghen-Schilling

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Juliette Thariat; Ellen Van Obberghen-Schilling; Sylvain Morinière; Frédérique Penault-Llorca; Séverine Racadot; Anne Sudaka; René-Jean Bensadoun; Francois Bertucci; Anne Cayre; Olivier Dassonville; Dominique De Raucourt; Marie-Christine Etienne-Grimaldi; Pascal Finetti; Lionel Geoffrois; Philippe Giraud; Dominique Grall; Gérard Milano
Contrasted outcomes to gefitinib on tumoral IGF1R expression in head and neck cancer patients receiving postoperative chemoradiation (GORTEC trial 2004-02).
Juliette Thariat; Laurence Veracini; René-Jean Bensadoun; Anne Cayre; Olivier Dassonville; Dominique De Raucourt; Marie-Christine Etienne-Grimaldi; Jean-Louis Formento; Mireille Francoual; Lionel Geoffrois; Philippe Giraud; Dominique Grall; Gérard Milano; Sylvain Morinière; Frédérique Penault-Llorca; Séverine Racadot; Ellen Van Obberghen-Schilling
Epidermal growth factor receptor protein detection in head and neck cancer patients: a many-faceted picture.
Ellen Van Obberghen-Schilling; Botond Cseh; Isabelle Gasser; Falk Saupe; Richard P Tucker; Gertraud Orend
Fibronectin and tenascin-C: accomplices in vascular morphogenesis during development and tumor growth.

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All Publications

2012: Juliette Thariat; Ellen Van Obberghen-Schilling; Sylvain Morinière; Frédérique Penault-Llorca; Séverine Racadot; Anne Sudaka; René-Jean Bensadoun; Francois Bertucci; Anne Cayre; Olivier Dassonville; Dominique De Raucourt; Marie-Christine Etienne-Grimaldi; Pascal Finetti; Lionel Geoffrois; Philippe Giraud; Dominique Grall; Gérard Milano
Contrasted outcomes to gefitinib on tumoral IGF1R expression in head and neck cancer patients receiving postoperative chemoradiation (GORTEC trial 2004-02).
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(18):5123-33.
2012: Juliette Thariat; Laurence Veracini; René-Jean Bensadoun; Anne Cayre; Olivier Dassonville; Dominique De Raucourt; Marie-Christine Etienne-Grimaldi; Jean-Louis Formento; Mireille Francoual; Lionel Geoffrois; Philippe Giraud; Dominique Grall; Gérard Milano; Sylvain Morinière; Frédérique Penault-Llorca; Séverine Racadot; Ellen Van Obberghen-Schilling
Epidermal growth factor receptor protein detection in head and neck cancer patients: a many-faceted picture.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(5):1313-22.
2011: Ellen Van Obberghen-Schilling; Botond Cseh; Isabelle Gasser; Falk Saupe; Richard P Tucker; Gertraud Orend
Fibronectin and tenascin-C: accomplices in vascular morphogenesis during development and tumor growth.
The International journal of developmental biology 2011;55(4-5):511-25.
2011: Sébastien Cagnol; Anna Mansour; Ellen Van Obberghen-Schilling; Jean-Claude Chambard
Raf-1 activation prevents caspase 9 processing downstream of apoptosome formation.
Journal of signal transduction 2011;2011():834948.
2010: Botond Cseh; Samantha Fernandez-Sauze; Dominique Grall; Sébastien Schaub; Eszter Doma; Ellen Van Obberghen-Schilling
Autocrine fibronectin directs matrix assembly and crosstalk between cell-matrix and cell-cell adhesion in vascular endothelial cells.
Journal of cell science 2010;123(Pt 22):3989-99.
2009: Samantha Fernandez-Sauze; Dominique Grall; Botond Cseh; Ellen Van Obberghen-Schilling
Regulation of fibronectin matrix assembly and capillary morphogenesis in endothelial cells by Rho family GTPases.
Experimental cell research 2009;315(12):2092-104.
2009: Fabio Stanchi; Carsten Grashoff; Carine Flore Nguemeni Yonga; Dominique Grall; Reinhard Fässler; Ellen Van Obberghen-Schilling
Molecular dissection of the ILK-PINCH-parvin triad reveals a fundamental role for the ILK kinase domain in the late stages of focal-adhesion maturation.
Journal of cell science 2009;122(Pt 11):1800-11.
2008: Paul Hofman; Catherine Butori; K Havet; Véronique Hofman; Eric Selva; N Guevara; José Santini; Ellen Van Obberghen-Schilling
Prognostic significance of cortactin levels in head and neck squamous cell carcinoma: comparison with epidermal growth factor receptor status.
British journal of cancer 2008;98(5):956-64.
2008: Ivana Fantozzi; Dominique Grall; Sébastien Cagnol; Fabio Stanchi; Anne Sudaka; Marie-Christine Brunstein; Alexandre Bozec; Jean-Louis Fischel; Gerard Milano; Ellen Van Obberghen-Schilling
Overexpression of cortactin in head and neck squamous cell carcinomas can be uncoupled from augmented EGF receptor expression.
Acta oncologica (Stockholm, Sweden) 2008;47(8):1502-12.
2007: Lia Rosso; Patricia M Pierson; Claire Golfier; Brigitta Peteri-Brunbäck; Christophe Deroanne; Ellen Van Obberghen-Schilling; Jean-Marc Mienville
Pituicyte stellation is prevented by RhoA-or Cdc42-dependent actin polymerization.
Cellular and molecular neurobiology 2007;27(6):791-804.
2006: Sylvie Maubant; Dominique Saint-Dizier; Morgane Boutillon; Françoise Perron-Sierra; Patrick J Casara; John A Hickman; Gordon C Tucker; Ellen Van Obberghen-Schilling
Blockade of alpha v beta3 and alpha v beta5 integrins by RGD mimetics induces anoikis and not integrin-mediated death in human endothelial cells.
Blood 2006;108(9):3035-44.
2006: Etienne Boulter; Dominique Grall; Sébastien Cagnol; Ellen Van Obberghen-Schilling
Regulation of cell-matrix adhesion dynamics and Rac-1 by integrin linked kinase.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(9):1489-91.
2006: Christine Varon; Florence Tatin; Violaine Moreau; Ellen Van Obberghen-Schilling; Samantha Fernandez-Sauze; Edith Reuzeau; Ijsbrand Kramer; Elisabeth Génot
Transforming growth factor beta induces rosettes of podosomes in primary aortic endothelial cells.
Molecular and cellular biology 2006;26(9):3582-94.
2006: Etienne Boulter; Ellen Van Obberghen-Schilling
Integrin-linked kinase and its partners: a modular platform regulating cell-matrix adhesion dynamics and cytoskeletal organization.
European journal of cell biology 2006;85(3-4):255-63.
2006: Sébastien Cagnol; Ellen Van Obberghen-Schilling; Jean-Claude Chambard
Prolonged activation of ERK1,2 induces FADD-independent caspase 8 activation and cell death.
Apoptosis : an international journal on programmed cell death 2006;11(3):337-46.
2004: Valérie Vouret-Craviari; Etienne Boulter; Dominique Grall; Cédric Matthews; Ellen Van Obberghen-Schilling
ILK is required for the assembly of matrix-forming adhesions and capillary morphogenesis in endothelial cells.
Journal of cell science 2004;117(Pt 19):4559-69.
2003: Maude Le Gall; Jean-Claude Chambard; Dominique Grall; Ellen Van Obberghen-Schilling
Adhesion-dependent control of Akt/protein kinase B occurs at multiple levels.
Journal of cellular physiology 2003;196(1):98-104.
2003: Valérie Vouret-Craviari; Dominique Grall; Ellen Van Obberghen-Schilling
Modulation of Rho GTPase activity in endothelial cells by selective proteinase-activated receptor (PAR) agonists.
Journal of thrombosis and haemostasis : JTH 2003;1(5):1103-11.
2002: Lia Rosso; Brigitta Peteri-Brunbäck; Valérie Vouret-Craviari; Christophe Deroanne; Ellen Van Obberghen-Schilling; Jean-Marc Mienville
Vasopressin and oxytocin reverse adenosine-induced pituicyte stellation via calcium-dependent activation of Cdc42.
The European journal of neuroscience 2002;16(12):2324-32.
2002: Valérie Vouret-Craviari; Christine Bourcier; Etienne Boulter; Ellen Van Obberghen-Schilling
Distinct signals via Rho GTPases and Src drive shape changes by thrombin and sphingosine-1-phosphate in endothelial cells.
Journal of cell science 2002;115(Pt 12):2475-84.
2002: Lia Rosso; Brigitta Peteri-Brunbäck; Valérie Vouret-Craviari; Christophe Deroanne; jean-denis troadec; S thirion; Ellen Van Obberghen-Schilling; Jean-Marc Mienville
RhoA inhibition is a key step in pituicyte stellation induced by A(1)-type adenosine receptor activation.
Glia 2002;38(4):351-62.
2000: K C Malcolm; Jean-Claude Chambard; Dominique Grall; Jacques Pouysségur; Ellen Van Obberghen-Schilling
Independent activation of endogenous p21-activated protein kinase-3 (PAK3) and JNK by thrombin in CCL39 fibroblasts.
Journal of cellular physiology 2000;185(2):235-43.
2000: Maude Le Gall; Jean-Claude Chambard; J P Breittmayer; Dominique Grall; Jacques Pouysségur; Ellen Van Obberghen-Schilling
The p42/p44 MAP kinase pathway prevents apoptosis induced by anchorage and serum removal.
Molecular biology of the cell 2000;11(3):1103-12.
1999: Valérie Vouret-Craviari; Dominique Grall; Gilles Flatau; Jacques Pouysségur; Patrice Boquet; Ellen Van Obberghen-Schilling
Effects of cytotoxic necrotizing factor 1 and lethal toxin on actin cytoskeleton and VE-cadherin localization in human endothelial cell monolayers.
Infection and immunity 1999;67(6):3002-8.
1998: Maude Le Gall; Dominique Grall; Jean-Claude Chambard; Jacques Pouysségur; Ellen Van Obberghen-Schilling
An anchorage-dependent signal distinct from p42/44 MAP kinase activation is required for cell cycle progression.
Oncogene 1998;17(10):1271-7.
1998: Valérie Vouret-Craviari; Patrice Boquet; Jacques Pouysségur; Ellen Van Obberghen-Schilling
Regulation of the actin cytoskeleton by thrombin in human endothelial cells: role of Rho proteins in endothelial barrier function.
Molecular biology of the cell 1998;9(9):2639-53.
1996: Y Chen; Dominique Grall; A E Salcini; P G Pelicci; Jacques Pouysségur; Ellen Van Obberghen-Schilling
Shc adaptor proteins are key transducers of mitogenic signaling mediated by the G protein-coupled thrombin receptor.
The EMBO journal 1996;15(5):1037-44.
1995: Ellen Van Obberghen-Schilling; Valérie Vouret-Craviari; Y H Chen; Dominique Grall; J C Chambard; Jacques Pouysségur
Thrombin and its receptor in growth control.
Annals of the New York Academy of Sciences 1995;766():431-41.
1995: Valérie Vouret-Craviari; Dominique Grall; J C Chambard; Ulla rasmussen; Jacques Pouysségur; Ellen Van Obberghen-Schilling
Post-translational and activation-dependent modifications of the G protein-coupled thrombin receptor.
The Journal of biological chemistry 1995;270(14):8367-72.
1995: Valérie Vouret-Craviari; Patrick Auberger; Jacques Pouysségur; Ellen Van Obberghen-Schilling
Distinct mechanisms regulate 5-HT2 and thrombin receptor desensitization.
The Journal of biological chemistry 1995;270(9):4813-21.
1994: Bernard Mari; V Imbert; Nathalie Belhacene; D F Far; Jean-François Peyron; Jacques Pouysségur; Ellen Van Obberghen-Schilling; Bernard Rossi; Patrick Auberger
Thrombin and thrombin receptor agonist peptide induce early events of T cell activation and synergize with TCR cross-linking for CD69 expression and interleukin 2 production.
The Journal of biological chemistry 1994;269(11):8517-23.
1993: Ulla rasmussen; Christian Gachet; Y Schlesinger; Daniel Hanau; Philippe Ohlmann; Ellen Van Obberghen-Schilling; Jacques Pouysségur; J P Cazenave; A Pavirani
A peptide ligand of the human thrombin receptor antagonizes alpha-thrombin and partially activates platelets.
The Journal of biological chemistry 1993;268(19):14322-8.
1993: Ellen Van Obberghen-Schilling; Ulla rasmussen; Valérie Vouret-Craviari; K U Lentes; A Pavirani; Jacques Pouysségur
Structure-activity analysis of synthetic alpha-thrombin-receptor-activating peptides.
The Biochemical journal 1993;292 ( Pt 3)():667-71.
1993: Jacques Pouysségur; G L'Allemain; Philippe Lenormand; G Pagès; A Pavirani; Ulla rasmussen; Ellen Van Obberghen-Schilling; Valérie Vouret-Craviari
Alpha-thrombin receptor and MAP kinases in the control of cell growth.
Nouvelle revue française d'hématologie 1993;35(3):263-4.
1993: Valérie Vouret-Craviari; Ellen Van Obberghen-Schilling; J C Scimeca; E Van Obberghen; Jacques Pouysségur
Differential activation of p44mapk (ERK1) by alpha-thrombin and thrombin-receptor peptide agonist.
The Biochemical journal 1993;289 ( Pt 1)():209-14.
1992: Valérie Vouret-Craviari; Ellen Van Obberghen-Schilling; Ulla rasmussen; A Pavirani; J P Lecocq; Jacques Pouysségur
Synthetic alpha-thrombin receptor peptides activate G protein-coupled signaling pathways but are unable to induce mitogenesis.
Molecular biology of the cell 1992;3(1):95-102.
1991: Ulla rasmussen; Valérie Vouret-Craviari; S Jallat; Y Schlesinger; G Pagès; A Pavirani; J P Lecocq; Jacques Pouysségur; Ellen Van Obberghen-Schilling
cDNA cloning and expression of a hamster alpha-thrombin receptor coupled to Ca2+ mobilization.
FEBS letters 1991;288(1-2):123-8.
1991: Ellen Van Obberghen-Schilling; Valérie Vouret-Craviari; R J Haslam; J C Chambard; Jacques Pouysségur
Cloning, functional expression and role in cell growth regulation of a hamster 5-HT2 receptor subtype.
Molecular endocrinology (Baltimore, Md.) 1991;5(7):881-9.
1990: J C Chambard; Ellen Van Obberghen-Schilling; R J Haslam; V Vouret; Jacques Pouysségur
Chinese hamster serotonin (5-HT) type 2 receptor cDNA sequence.
Nucleic acids research 1990;18(17):5282.
1990: Ellen Van Obberghen-Schilling; J C Chambard; Philippe Lory; Joël Nargeot; Jacques Pouysségur
Functional expression of Ca2(+)-mobilizing alpha-thrombin receptors in mRNA-injected Xenopus oocytes.
FEBS letters 1990;262(2):330-4.
1985: Ellen Van Obberghen-Schilling; J C Chambard; S Paris; G L'Allemain; Jacques Pouysségur
alpha-Thrombin-induced early mitogenic signalling events and G0 to S-phase transition of fibroblasts require continual external stimulation.
The EMBO journal 1985;4(11):2927-32.
1983: Ellen Van Obberghen-Schilling; R Pérez-Rodríguez; A Franchi; J C Chambard; Jacques Pouysségur
Analysis of growth factor "relaxation" in Chinese hamster lung fibroblasts required for tumoral expression.
Journal of cellular physiology 1983;115(2):123-30.
1982: Jacques Pouysségur; J C Chambard; A Franchi; S Paris; Ellen Van Obberghen-Schilling
Growth factor activation of an amiloride-sensitive Na+/H+ exchange system in quiescent fibroblasts: coupling to ribosomal protein S6 phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(13):3935-9.
1982: Ellen Van Obberghen-Schilling; R Pérez-Rodriguez; Jacques Pouysségur
Hirudin, a probe to analyze the growth-promoting activity of thrombin in fibroblasts; reevaluation of the temporal action of competence factors.
Biochemical and biophysical research communications 1982;106(1):79-86.
1981: R Pérez-Rodriguez; J C Chambard; Ellen Van Obberghen-Schilling; A Franchi; Jacques Pouysségur
Emergence of hamster fibroblast tumors in nude mice--evidence for in vivo selection leading to loss of growth factor requirement.
Journal of cellular physiology 1981;109(3):387-96.