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Luk Van Parijs

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TOP 3
Luk Van Parijs; Yosef Refaeli; James D Lord; Brad H Nelson; Abul K Abbas; David Baltimore
Retraction. Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death.
Luk Van Parijs; Yosef Refaeli; Abul K Abbas; David Baltimore
Retraction. Autoimmunity as a consequence of retrovirus-mediated expression of C-FLIP in lymphocytes.
Luk Van Parijs; Daniel A Peterson; Abul K Abbas
Retraction. The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens.

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All Publications

2009: Luk Van Parijs; Yosef Refaeli; James D Lord; Brad H Nelson; Abul K Abbas; David Baltimore
Retraction. Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death.
Immunity 2009;30(4):611.
2009: Luk Van Parijs; Yosef Refaeli; Abul K Abbas; David Baltimore
Retraction. Autoimmunity as a consequence of retrovirus-mediated expression of C-FLIP in lymphocytes.
Immunity 2009;30(4):612.
2009: Luk Van Parijs; Daniel A Peterson; Abul K Abbas
Retraction. The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens.
Immunity 2009;30(4):611.
2006: Qiang Zhang; Thomas L Jang; Ximing Yang; Irwin Park; Robert E Meyer; Shilajit Kundu; Michael Pins; Borko Javonovic; Timothy Kuzel; Seong-Jin Kim; Luk Van Parijs; Norm Smith; Larry Wong; Norman M Greenberg; Yinglu Guo; Chung Lee
Infiltration of tumor-reactive transforming growth factor-beta insensitive CD8+ T cells into the tumor parenchyma is associated with apoptosis and rejection of tumor cells.
The Prostate 2006;66(3):235-47.
2005: Christopher P Dillon; Peter Sandy; Alessio Nencioni; Stephan Kissler; Douglas A Rubinson; Luk Van Parijs
Rnai as an experimental and therapeutic tool to study and regulate physiological and disease processes.
Annual review of physiology 2005;67():147-73.
2004: Stephan Kissler; Luk Van Parijs
Exploring the genetic basis of disease using RNA interference.
Expert review of molecular diagnostics 2004;4(5):645-51.
2004: Andrea Ventura; Alexander Meissner; Christopher P Dillon; Michael McManus; Phillip A Sharp; Luk Van Parijs; Rudolf Jaenisch; Tyler Jacks
Cre-lox-regulated conditional RNA interference from transgenes.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(28):10380-5.
2004: Wu-Shiun Hou; Luk Van Parijs
A Bcl-2-dependent molecular timer regulates the lifespan and immunogenicity of dendritic cells.
Nature immunology 2004;5(6):583-9.
2004: Alessio Nencioni; Peter Sandy; Christopher P Dillon; Stephan Kissler; Peter Blume-Jensen; Luk Van Parijs
RNA interference for the identification of disease-associated genes.
Current opinion in molecular therapeutics 2004;6(2):136-40.
2004: Alberto Ballestrero; Alessio Nencioni; Davide Boy; Ilaria Rocco; Anna Garuti; Giuseppe Sandro Mela; Luk Van Parijs; Peter Brossart; Sebastian Wesselborg; Franco Patrone
Tumor necrosis factor-related apoptosis-inducing ligand cooperates with anticancer drugs to overcome chemoresistance in antiapoptotic Bcl-2 family members expressing jurkat cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(4):1463-70.
2004: Jim (Jianxun) Song; Shahram Salek-Ardakani; Paul R Rogers; Mary Cheng; Luk Van Parijs; Michael Croft
The costimulation-regulated duration of PKB activation controls T cell longevity.
Nature immunology 2004;5(2):150-8.
2003: Alessio Nencioni; Kirsten Lauber; Frank Grünebach; Luk Van Parijs; Claudio Denzlinger; Sebastian Wesselborg; Peter Brossart
Cyclopentenone prostaglandins induce lymphocyte apoptosis by activating the mitochondrial apoptosis pathway independent of external death receptor signaling.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(10):5148-56.
2003: Andrey Antov; Lili Yang; Monika Vig; David Baltimore; Luk Van Parijs
Essential role for STAT5 signaling in CD25+CD4+ regulatory T cell homeostasis and the maintenance of self-tolerance.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(7):3435-41.
2003: Katrin Layer; Guosheng Lin; Alessio Nencioni; Wei Hu; Adam Schmucker; Andrey N Antov; Xiaoyu Li; Satoshi Takamatsu; Timothy Chevassut; Nancy A Dower; Stacey L Stang; David Beier; Janet Buhlmann; Roderick T Bronson; Keith B Elkon; James C Stone; Luk Van Parijs; Bing Lim
Autoimmunity as the consequence of a spontaneous mutation in Rasgrp1.
Immunity 2003;19(2):243-55.
2003: Ye Zheng; Monika Vig; Jesse Lyons; Luk Van Parijs; Amer A Beg
Combined deficiency of p50 and cRel in CD4+ T cells reveals an essential requirement for nuclear factor kappaB in regulating mature T cell survival and in vivo function.
The Journal of experimental medicine 2003;197(7):861-74.
2003: Douglas A Rubinson; Christopher P Dillon; Adam V Kwiatkowski; Claudia Sievers; Lili Yang; Johnny Kopinja; Dina L Rooney; Mingdi Zhang; Melanie M Ihrig; Michael McManus; Frank B Gertler; Martin L Scott; Luk Van Parijs
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference.
Nature genetics 2003;33(3):401-6.
2002: Ali H Shah; William B Tabayoyong; Shilajit D Kundu; Seong-Jin Kim; Luk Van Parijs; Victoria C Liu; Eugene Kwon; Norman M Greenberg; Chung Lee
Suppression of tumor metastasis by blockade of transforming growth factor beta signaling in bone marrow cells through a retroviral-mediated gene therapy in mice.
Cancer research 2002;62(24):7135-8.
2002: Michael McManus; Brian B Haines; Christopher P Dillon; Charles E Whitehurst; Luk Van Parijs; Jianzhu Chen; Phillip A Sharp
Small interfering RNA-mediated gene silencing in T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5754-60.
2002: Yosef Refaeli; Luk Van Parijs; Stephen I Alexander; Abul K Abbas
Interferon gamma is required for activation-induced death of T lymphocytes.
The Journal of experimental medicine 2002;196(7):999-1005.
2002: Ali H Shah; William B Tabayoyong; Simon Y Kimm; Seong-Jin Kim; Luk Van Parijs; Chung Lee
Reconstitution of lethally irradiated adult mice with dominant negative TGF-beta type II receptor-transduced bone marrow leads to myeloid expansion and inflammatory disease.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(7):3485-91.
2002: Hong Ruan; Nir Hacohen; Todd R Golub; Luk Van Parijs; Harvey Lodish
Tumor necrosis factor-alpha suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-kappaB activation by TNF-alpha is obligatory.
Diabetes 2002;51(5):1319-36.
2002: Lili Yang; Xiao-Feng Qin; David Baltimore; Luk Van Parijs
Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus-mediated expression of TCR cDNAs in hematopoietic precursor cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(9):6204-9.
2002: Erin Kelly; Angela Won; Yosef Refaeli; Luk Van Parijs
IL-2 and related cytokines can promote T cell survival by activating AKT.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(2):597-603.
2001: C Lois; Yosef Refaeli; Xiao-Feng Qin; Luk Van Parijs
Retroviruses as tools to study the immune system.
Current opinion in immunology 2001;13(4):496-504.
2000: S R Cherry; Detlev Biniszkiewicz; Luk Van Parijs; David Baltimore; Rudolf Jaenisch
Retroviral expression in embryonic stem cells and hematopoietic stem cells.
Molecular and cellular biology 2000;20(20):7419-26.
1999: Luk Van Parijs; Yosef Refaeli; Abul K Abbas; David Baltimore
Autoimmunity as a consequence of retrovirus-mediated expression of C-FLIP in lymphocytes.
Immunity 1999;11(6):763-70.
1999: Luk Van Parijs; Yosef Refaeli; JD Lord; Brad H Nelson; Abul K Abbas; David Baltimore
Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death.
Immunity 1999;11(3):281-8.
1999: Yosef Refaeli; Luk Van Parijs; Abul K Abbas
Genetic models of abnormal apoptosis in lymphocytes.
Immunological reviews 1999;169():273-82.
1998: Yosef Refaeli; Luk Van Parijs; CA London; J Tschopp; Abul K Abbas
Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis.
Immunity 1998;8(5):615-23.
1998: Luk Van Parijs; Abul K Abbas
Homeostasis and self-tolerance in the immune system: turning lymphocytes off.
Science (New York, N.Y.) 1998;280(5361):243-8.
1998: Luk Van Parijs; AJ Biuckians; Abul K Abbas
Functional roles of Fas and Bcl-2-regulated apoptosis of T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(5):2065-71.
1998: Luk Van Parijs; Daniel A Peterson; Abul K Abbas
The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens.
Immunity 1998;8(2):265-74.
1998: Luk Van Parijs; Victor Perez Quinones; Abul K Abbas
Mechanisms of peripheral T cell tolerance.
Novartis Foundation symposium 1998;215():5-14; discussion 14-20, 33-40.
1997: Luk Van Parijs; M P Sethna; A Nicola Schweitzer; F Borriello; Arlene H Sharpe; Abul K Abbas
Functional consequences of dysregulated B7-1 (CD80) and B7-2 (CD86) expression in B or T lymphocytes of transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(11):5336-44.
1997: Luk Van Parijs; Victor Perez Quinones; AJ Biuckians; ROBERT G MAKI; CA London; Abul K Abbas
Role of interleukin 12 and costimulators in T cell anergy in vivo.
The Journal of experimental medicine 1997;186(7):1119-28.
1997: Luk Van Parijs; AJ Biuckians; A Ibragimov; F W Alt; D M Willerford; Abul K Abbas
Functional responses and apoptosis of CD25 (IL-2R alpha)-deficient T cells expressing a transgenic antigen receptor.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(8):3738-45.
1997: Victor Perez Quinones; Luk Van Parijs; AJ Biuckians; X X Zheng; TB Strom; Abul K Abbas
Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.
Immunity 1997;6(4):411-7.
1996: Luk Van Parijs; Abul K Abbas
Role of Fas-mediated cell death in the regulation of immune responses.
Current opinion in immunology 1996;8(3):355-61.
1996: Luk Van Parijs; A Ibraghimov; Abul K Abbas
The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance.
Immunity 1996;4(3):321-8.
1995: Abul K Abbas; Victor Perez Quinones; Luk Van Parijs; R C Wong
Differentiation and tolerance of CD4+ T lymphocytes.
Ciba Foundation symposium 1995;195():7-13; discussion 13-9.
1994: M P Sethna; Luk Van Parijs; Arlene H Sharpe; Abul K Abbas; Gordon J Freeman
A negative regulatory function of B7 revealed in B7-1 transgenic mice.
Immunity 1994;1(5):415-21.