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Jeremy van Raamsdonk

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Jeremy M van Raamsdonk; Zoe Murphy; David M Selva; Reza Hamidizadeh; Jacqueline Pearson; Asa Petersén; Maria Björkqvist; Cameron Muir; Ian R A Mackenzie; Geoffrey L Hammond; A Wayne Vogl; Michael R Hayden; Blair R Leavitt
Testicular degeneration in Huntington disease.
Jeremy M van Raamsdonk; Simon Warby; Michael R Hayden
Selective degeneration in YAC mouse models of Huntington disease.
Jeremy M van Raamsdonk; Martina Metzler; Elizabeth J Slow; Jacqueline Pearson; Claudia Schwab; Jeffrey Carroll; Graham Kyrenia Rona; Blair R Leavitt; Michael R Hayden
Phenotypic abnormalities in the YAC128 mouse model of Huntington disease are penetrant on multiple genetic backgrounds and modulated by strain.

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All Publications

2007: Jeremy M van Raamsdonk; Zoe Murphy; David M Selva; Reza Hamidizadeh; Jacqueline Pearson; Asa Petersén; Maria Björkqvist; Cameron Muir; Ian R A Mackenzie; Geoffrey L Hammond; A Wayne Vogl; Michael R Hayden; Blair R Leavitt
Testicular degeneration in Huntington disease.
Neurobiology of disease 2007;26(3):512-20.
2007: Jeremy M van Raamsdonk; Simon Warby; Michael R Hayden
Selective degeneration in YAC mouse models of Huntington disease.
Brain research bulletin 2007;72(2-3):124-31.
2007: Jeremy M van Raamsdonk; Martina Metzler; Elizabeth J Slow; Jacqueline Pearson; Claudia Schwab; Jeffrey Carroll; Graham Kyrenia Rona; Blair R Leavitt; Michael R Hayden
Phenotypic abnormalities in the YAC128 mouse model of Huntington disease are penetrant on multiple genetic backgrounds and modulated by strain.
Neurobiology of disease 2007;26(1):189-200.
2006: Yu Zhang; Blair R Leavitt; Jeremy M van Raamsdonk; Ioannis Dragatsis; Dan Goldowitz; Marcy E MacDonald; Michael R Hayden; Robert M Friedlander
Huntingtin inhibits caspase-3 activation.
The EMBO journal 2006;25(24):5896-906.
2006: J Thiele; Jeremy M van Raamsdonk
Gene discovery in methylmalonic aciduria and homocystinuria.
Clinical genetics 2006;69(5):402-3.
2006: Jeremy M van Raamsdonk
Loss of function mutations in SIL1 cause Marinesco-Sjögren syndrome.
Clinical genetics 2006;69(5):399-400.
2006: Jeremy M van Raamsdonk; William T Gibson; Jacqueline Pearson; Zoe Murphy; Ge Lu; Blair R Leavitt; Michael R Hayden
Body weight is modulated by levels of full-length huntingtin.
Human molecular genetics 2006;15(9):1513-23.
2006: Blair R Leavitt; Jeremy M van Raamsdonk; Jacqueline Shehadeh; Herman B Fernandes; Zoe Murphy; Graham Kyrenia Rona; Cheryl L Wellington; Lynn A Raymond; Michael R Hayden
Wild-type huntingtin protects neurons from excitotoxicity.
Journal of neurochemistry 2006;96(4):1121-9.
2006: Jeremy M van Raamsdonk; Jacqueline Pearson; Zoe Murphy; Michael R Hayden; Blair R Leavitt
Wild-type huntingtin ameliorates striatal neuronal atrophy but does not prevent other abnormalities in the YAC128 mouse model of Huntington disease.
BMC neuroscience 2006;7():80.
2005: Jeremy M van Raamsdonk; Zoe Murphy; Elizabeth J Slow; Blair R Leavitt; Michael R Hayden
Selective degeneration and nuclear localization of mutant huntingtin in the YAC128 mouse model of Huntington disease.
Human molecular genetics 2005;14(24):3823-35.
2005: Jeremy M van Raamsdonk; Jacqueline Pearson; Daniel A Rogers; Ge Lu; Vilte E Barakauskas; Alasdair M Barr; William Honer; Michael R Hayden; Blair R Leavitt
Ethyl-EPA treatment improves motor dysfunction, but not neurodegeneration in the YAC128 mouse model of Huntington disease.
Experimental neurology 2005;196(2):266-72.
2005: Jeremy M van Raamsdonk; Jacqueline Pearson; Craig D C Bailey; Daniel A Rogers; Gail Johnson; Michael R Hayden; Blair R Leavitt
Cystamine treatment is neuroprotective in the YAC128 mouse model of Huntington disease.
Journal of neurochemistry 2005;95(1):210-20.
2005: John Pinto; Jeremy M van Raamsdonk; Blair R Leavitt; Michael R Hayden; Thomas M Jeitner; Howard T Thaler; Boris Krasnikov; Arthur J L Cooper
Treatment of YAC128 mice and their wild-type littermates with cystamine does not lead to its accumulation in plasma or brain: implications for the treatment of Huntington disease.
Journal of neurochemistry 2005;94(4):1087-101.
2005: Jeremy M van Raamsdonk; Jacqueline Pearson; Daniel A Rogers; Nagat Bissada; A Wayne Vogl; Michael R Hayden; Blair R Leavitt
Loss of wild-type huntingtin influences motor dysfunction and survival in the YAC128 mouse model of Huntington disease.
Human molecular genetics 2005;14(10):1379-92.
2005: Jeremy M van Raamsdonk; Jacqueline Pearson; Elizabeth J Slow; Sazzad M Hossain; Blair R Leavitt; Michael R Hayden
Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(16):4169-80.
2003: Elizabeth J Slow; Jeremy M van Raamsdonk; Daniel Rogers; Sarah H Coleman; Graham Kyrenia Rona; Yu Deng; Rosemary Oh; Nagat Bissada; Sazzad M Hossain; Yu-Zhou Yang; Xiao-Jiang Li; Elizabeth M Simpson; Claire-Anne Gutekunst; Blair R Leavitt; Michael R Hayden
Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.
Human molecular genetics 2003;12(13):1555-67.
2002: Cheryl L Wellington; Lisa M Ellerby; Claire-Anne Gutekunst; Danny Rogers; Simon Warby; Graham Kyrenia Rona; Odell Loubser; Jeremy M van Raamsdonk; Roshni R Singaraja; Yu-Zhou Yang; Juliette Gafni; Dale E Bredesen; Steven M Hersch; Blair R Leavitt; Sophie Roy; Donald W Nicholson; Michael R Hayden
Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(18):7862-72.