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Bennard van Ravenzwaay

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Steffen Schneider; Roland Buesen; Sibylle Gröters; Heike Marxfeld; Bennard van Ravenzwaay
Vinclozolin--no transgenerational inheritance of anti-androgenic effects after maternal exposure during organogenesis via the intraperitoneal route.
Susanne N Kolle; Annette Mehling; Kristie M Sullivan; Bennard van Ravenzwaay; Robert LANDSIEDEL
Erratum to "Applicability of in vitro tests for skin irritation and corrosion to regulatory classification schemes: substantiating test strategies with data from routine studies" [Regul. Toxicol. Pharmacol. (2012) 402-414].
Susanne N Kolle; David A Basketter; Silvia Casati; William S Stokes; Judy Strickland; Bennard van Ravenzwaay; Hans-Werner Vohr; Robert LANDSIEDEL
Performance standards and alternative assays: practical insights from skin sensitization.

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2013: Steffen Schneider; Roland Buesen; Sibylle Gröters; Heike Marxfeld; Bennard van Ravenzwaay
Vinclozolin--no transgenerational inheritance of anti-androgenic effects after maternal exposure during organogenesis via the intraperitoneal route.
Reproductive toxicology (Elmsford, N.Y.) 2013;37():6-14.
2013: Susanne N Kolle; Annette Mehling; Kristie M Sullivan; Bennard van Ravenzwaay; Robert LANDSIEDEL
Erratum to "Applicability of in vitro tests for skin irritation and corrosion to regulatory classification schemes: substantiating test strategies with data from routine studies" [Regul. Toxicol. Pharmacol. (2012) 402-414].
Regulatory toxicology and pharmacology : RTP 2013;65(3):366-78.
2013: Susanne N Kolle; David A Basketter; Silvia Casati; William S Stokes; Judy Strickland; Bennard van Ravenzwaay; Hans-Werner Vohr; Robert LANDSIEDEL
Performance standards and alternative assays: practical insights from skin sensitization.
Regulatory toxicology and pharmacology : RTP 2013;65(2):278-85.
2013: Ursula G Sauer; Bennard van Ravenzwaay; Sandra Vogel; Annemarie Hess; Susanne N Kolle; L Ma-Hock; Robert LANDSIEDEL
In vivo-in vitro comparison of acute respiratory tract toxicity using human 3D airway epithelial models and human A549 and murine 3T3 monolayer cell systems.
Toxicology in vitro : an international journal published in association with BIBRA 2013;27(1):174-90.
2013: Tzutzuy Ramirez; Bjoern Riefke; Mark Seymour; Nigel Skinner; Lena Smirnova; Bennard van Ravenzwaay; Elwin Verheij; Silvia Wagner; Andreas Luch; Fozia Noor; Erik Peter; Frederic Y Bois; Malcolm R Clench; Muireann Coen; Mardas Daneshian; Beth Donley; Drew R Ekman; Eric Fabian; Steven M Fischer; Claude Guillou; Thomas Hartung; Joachim Heuer; Helena T Hogberg; Harald Jungnickel; Hennicke Kamp; Hector C Keun; Gerhard Krennrich; Eckart Krupp; Marcel Leist
Metabolomics in toxicology and preclinical research.
ALTEX 2013;30(2):209-25.
2012: Susanne N Kolle; Annette Mehling; Kristie M Sullivan; Bennard van Ravenzwaay; Robert LANDSIEDEL
Applicability of in vitro tests for skin irritation and corrosion to regulatory classification schemes: substantiating test strategies with data from routine studies.
Regulatory toxicology and pharmacology : RTP 2012;64(3):402-14.
2012: Hennicke Kamp; G Krennrich; E Leibold; R Looser; Werner Mellert; A Prokoudine; V Strauss; E Fabian; M Herold; T Walk; J Wiemer; Bennard van Ravenzwaay
Reproducibility and robustness of metabolome analysis in rat plasma of 28-day repeated dose toxicity studies.
Toxicology letters 2012;215(2):143-9.
2012: Bennard van Ravenzwaay; Roland Buesen; M Dammann; Burkhard Flick; S Schneider
The threshold of toxicological concern for prenatal developmental toxicity in rabbits and a comparison to TTC values in rats.
Regulatory toxicology and pharmacology : RTP 2012;64(1):1-8.
2012: Christine Jäckh; Eric Fabian; Bennard van Ravenzwaay; Robert LANDSIEDEL
Relevance of xenobiotic enzymes in human skin in vitro models to activate pro-sensitizers.
Journal of immunotoxicology 2012;9(4):426-38.
2012: Hennicke Kamp; G Krennrich; R Looser; W Mattes; Werner Mellert; A Prokoudine; P Ruiz-Noppinger; V Strauss; E Fabian; S Groeters; M Herold; T Walk; J Wiemer; Bennard van Ravenzwaay
Application of in vivo metabolomics to preclinical/toxicological studies: case study on phenytoin-induced systemic toxicity.
Bioanalysis 2012;4(18):2291-301.
2012: Bennard van Ravenzwaay; Gunnar Brunborg; Jos Kleinjans
Conclusions and outlook.
Mutation research 2012;746(2):171-2.
2012: Bennard van Ravenzwaay; Gunnar Brunborg; Malyka Galay Burgos; Jos Kleinjans; Hendrik Vrijhof
Use of 'omics to elucidate mechanism of action and integration of 'omics in a systems biology concept.
Mutation research 2012;746(2):95-6.
2012: Bennard van Ravenzwaay; T Walk; E Fabian; M Herold; Hennicke Kamp; M D Kapp; G Krennrich; R Looser; Werner Mellert; A Prokoudine; V Strauss; J Wiemer
Metabolomics: a tool for early detection of toxicological effects and an opportunity for biology based grouping of chemicals-from QSAR to QBAR.
Mutation research 2012;746(2):144-50.
2012: Annette Mehling; Tzutzuy Ramirez; Wera Teubner; Bennard van Ravenzwaay; Tobias Eltze; Tove Eriksson; Susanne Kolle; Robert LANDSIEDEL
Non-animal test methods for predicting skin sensitization potentials.
Archives of toxicology 2012;86(8):1273-95.
2012: Caroline Bauch; Tobias Eltze; Eric Fabian; Susanne N Kolle; Annette Mehling; Tzutzuy Ramirez; Wera Teubner; Bennard van Ravenzwaay; Robert LANDSIEDEL
Putting the parts together: combining in vitro methods to test for skin sensitizing potentials.
Regulatory toxicology and pharmacology : RTP 2012;63(3):489-504.
2012: Susanne N Kolle; David Basketter; Armin O Gamer; Arnhild Schrage; Bennard van Ravenzwaay; Robert LANDSIEDEL
Further experience with the local lymph node assay using standard radioactive and nonradioactive cell count measurements.
Journal of applied toxicology : JAT 2012;32(8):597-607.
2012: David Basketter; Armin O Gamer; Naveed Honarvar; Susanne N Kolle; Arnhild Schrage; Bennard van Ravenzwaay; Robert LANDSIEDEL
Experience with local lymph node assay performance standards using standard radioactivity and nonradioactive cell count measurements.
Journal of applied toxicology : JAT 2012;32(8):590-6.
2012: Robert LANDSIEDEL; L Ma-Hock; Bennard van Ravenzwaay; Hans-Juergen Haussmann; Martin Kayser; Karin Wiench
Inhalation studies for the safety assessment of nanomaterials: status quo and the way forward.
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 2012;4(4):399-413.
2012: Robert LANDSIEDEL; L Ma-Hock; Bennard van Ravenzwaay; Karin Wiench; Wendel Wohlleben; Eric Fabian; Franz Oesch
Toxico-/biokinetics of nanomaterials.
Archives of toxicology 2012;86(7):1021-60.
2012: Susanne N Kolle; Tzutzuy Ramirez; Volker Strauss; Roland Buesen; Burkhard Flick; Hennicke Kamp; Bennard van Ravenzwaay
A testing strategy for the identification of mammalian, systemic endocrine disruptors with particular focus on steroids.
Regulatory toxicology and pharmacology : RTP 2012;63(2):259-78.
2012: Christoph L Klein; L Ma-Hock; Bennard van Ravenzwaay; Martin Wiemann; Karin Wiench; Robert LANDSIEDEL
Hazard identification of inhaled nanomaterials: making use of short-term inhalation studies.
Archives of toxicology 2012;86(7):1137-51.
2012: Markus Schulz; Volker Strauss; Silke Treumann; Bennard van Ravenzwaay; Sandra Brill; Sibylle Gröters; L Ma-Hock; Robert LANDSIEDEL
Investigation on the genotoxicity of different sizes of gold nanoparticles administered to the lungs of rats.
Mutation research 2012;745(1-2):51-7.
2012: V Strauss; T Walk; J Wiemer; E Fabian; M Herold; Hennicke Kamp; G Krennrich; E Leibold; R Looser; Werner Mellert; A Prokoudine; Bennard van Ravenzwaay
Increased toxicity when fibrates and statins are administered in combination--a metabolomics approach with rats.
Toxicology letters 2012;211(2):187-200.
2012: Amechi Chukwudebe; Daniela Contri; Martina Dammann; Sibylle Groeters; Uwe Kaspers; Laura Privalle; Andrew Reed; Volker Strauss; Christine Wandelt; Bennard van Ravenzwaay
Health and nutritional status of Wistar rats following subchronic exposure to CV127 soybeans.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012;50(3-4):956-71.
2011: Werner Mellert; A Prokoudine; V Strauss; E Fabian; M Herold; Hennicke Kamp; M Kapp; G Krennrich; R Looser; T Walk; J Wiemer; Bennard van Ravenzwaay
Nutritional impact on the plasma metabolome of rats.
Toxicology letters 2011;207(2):173-81.
2011: Susanne N Kolle; Bennard van Ravenzwaay; Britta Wareing; Helena Kandarova; Robert LANDSIEDEL
In-house validation of the EpiOcular(TM) eye irritation test and its combination with the bovine corneal opacity and permeability test for the assessment of ocular irritation.
Alternatives to laboratory animals : ATLA 2011;39(4):365-87.
2011: Christine Jäckh; Veronika Blatz; Eric Fabian; Katharina Guth; Kerstin Reisinger; Bennard van Ravenzwaay; Robert LANDSIEDEL
Characterization of enzyme activities of Cytochrome P450 enzymes, Flavin-dependent monooxygenases, N-acetyltransferases and UDP-glucuronyltransferases in human reconstructed epidermis and full-thickness skin models.
Toxicology in vitro : an international journal published in association with BIBRA 2011;25(6):1209-14.
2011: Susanne N Kolle; Gerhard Krennrich; Robert LANDSIEDEL; Stephanie Melching-Kollmuss; Bennard van Ravenzwaay
Assessment of combinations of antiandrogenic compounds vinclozolin and flutamide in a yeast based reporter assay.
Regulatory toxicology and pharmacology : RTP 2011;60(3):373-80.
2011: Arnhild Schrage; Markus Schulz; Bennard van Ravenzwaay; Katja Hempel; Susanne N Kolle; Robert LANDSIEDEL
Refinement and reduction of acute oral toxicity testing: a critical review of the use of cytotoxicity data.
Alternatives to laboratory animals : ATLA 2011;39(3):273-95.
2011: G U Balcke; S N Kolle; Hennicke Kamp; B Bethan; R Looser; S Wagner; Robert Landsiedel; Bennard van Ravenzwaay
Linking energy metabolism to dysfunctions in mitochondrial respiration--a metabolomics in vitro approach.
Toxicology letters 2011;203(3):200-9.
2011: Arnhild Schrage; Susanne N Kolle; Maria C R Moreno; Kimberly Norman; Hans Raabe; rodger curren; Bennard van Ravenzwaay; Robert LANDSIEDEL
The bovine corneal opacity and permeability test in routine ocular irritation testing and its improvement within the limits of OECD test guideline 437.
Alternatives to laboratory animals : ATLA 2011;39(1):37-53.
2011: Steffen Schneider; Wolfgang Kaufmann; Volker Strauss; Bennard van Ravenzwaay
Vinclozolin: a feasibility and sensitivity study of the ILSI-HESI F1-extended one-generation rat reproduction protocol.
Regulatory toxicology and pharmacology : RTP 2011;59(1):91-100.
2010: Bennard van Ravenzwaay
Initiatives to decrease redundancy in animal testing of pesticides.
ALTEX 2010;27(3):159-61.
2009: Lan Ma-Hock; Silke Treumann; Volker Strauss; Sandra Brill; Frederic Luizi; Michael Mertler; Karin Wiench; Armin O Gamer; Bennard van Ravenzwaay; Robert LANDSIEDEL
Inhalation toxicity of multiwall carbon nanotubes in rats exposed for 3 months.
Toxicological sciences : an official journal of the Society of Toxicology 2009;112(2):468-81.
2009: Nigel Moore; Susanne Bremer; Neil Carmichael; George Daston; Matt Dent; Wassila Gaoua-Chapelle; Nina Hallmark; Thomas Hartung; Beate Holzum; Ulrich Hübel; Marie-Louise Meisters; Steffen Schneider; Bennard van Ravenzwaay; Christa Hennes
A modular approach to the extended one-generation reproduction toxicity study. The outcome of an ECETOC Task Force and International ECETOC/ECVAM Workshop.
Alternatives to laboratory animals : ATLA 2009;37(2):219-25.
2009: Lan Ma-Hock; Silke Burkhardt; Volker Strauss; Armin O Gamer; Karin Wiench; Bennard van Ravenzwaay; Robert LANDSIEDEL
Development of a short-term inhalation test in the rat using nano-titanium dioxide as a model substance.
Inhalation toxicology 2009;21(2):102-18.
2008: Steffen Schneider; Wolfgang Kaufmann; Roland Buesen; Bennard van Ravenzwaay
Vinclozolin--the lack of a transgenerational effect after oral maternal exposure during organogenesis.
Reproductive toxicology (Elmsford, N.Y.) 2008;25(3):352-60.
2007: Klaus Deckardt; I Weber; U Kaspers; Jürgen Hellwig; Henk Tennekes; Bennard van Ravenzwaay
The effects of inhalation anaesthetics on common clinical pathology parameters in laboratory rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2007;45(9):1709-18.
2007: L Ma-Hock; Armin Gamer; Robert LANDSIEDEL; E Leibold; T Frechen; B Sens; M Linsenbuehler; Bennard van Ravenzwaay
Generation and characterization of test atmospheres with nanomaterials.
Inhalation toxicology 2007;19(10):833-48.
2007: G Coelho-Palermo Cunha; Bennard van Ravenzwaay
Standardization of the perchlorate discharge assay for thyroid toxicity testing in rats.
Regulatory toxicology and pharmacology : RTP 2007;48(3):270-8.
2007: Bennard van Ravenzwaay; G Coelho-Palermo Cunha; E Leibold; R Looser; Werner Mellert; A Prokoudine; T Walk; J Wiemer
The use of metabolomics for the discovery of new biomarkers of effect.
Toxicology letters 2007;172(1-2):21-8.
2007: Werner Mellert; Klaus Deckardt; Wolfgang Kaufmann; Bennard van Ravenzwaay
Ethylbenzene: 4- and 13-week rat oral toxicity.
Archives of toxicology 2007;81(5):361-70.
2007: L Ma-Hock; Armin Gamer; Klaus Deckardt; E Leibold; Bennard van Ravenzwaay
Determination of pulmonary irritant threshold concentrations of hexamethylene-1,6-diisocyanate (HDI) prepolymers by bronchoalveolar lavage in acute rat inhalation studies according to TRGS 430.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2007;45(2):237-43.
2006: Armin Gamer; E Leibold; Bennard van Ravenzwaay
The in vitro absorption of microfine zinc oxide and titanium dioxide through porcine skin.
Toxicology in vitro : an international journal published in association with BIBRA 2006;20(3):301-7.
2006: John E Doe; Alan R Boobis; Ann Blacker; Vicki Dellarco; Nancy G Doerrer; Claire Franklin; Jay I Goodman; Joel M Kronenberg; Richard Lewis; Ernest E Mcconnell; Thierry Mercier; Angelo Moretto; Canice Nolan; Stephanie Padilla; Whang Phang; Roland Solecki; Lorraine Tilbury; Bennard van Ravenzwaay; Douglas Wolf
A tiered approach to systemic toxicity testing for agricultural chemical safety assessment.
Critical reviews in toxicology 2006;36(1):37-68.
2005: Awni Sarrif; Joost H M van Delft; Frederik J Van Schooten; Timothy W Gant; Barry M Elliott; Bennard van Ravenzwaay; Harry van Steeg; Hendrik Vrijhof
Toxicogenomics in genetic toxicology and hazard determination: introduction and overview.
Mutation research 2005;575(1-2):1-3.
2005: Steffen Schneider; Klaus Deckardt; Jürgen Hellwig; Karin Küttler; Werner Mellert; Stefan Schulte; Bennard van Ravenzwaay
Octyl methoxycinnamate: two generation reproduction toxicity in Wistar rats by dietary administration.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2005;43(7):1083-92.
2005: G Coelho-Palermo Cunha; Bennard van Ravenzwaay
Evaluation of mechanisms inducing thyroid toxicity and the ability of the enhanced OECD Test Guideline 407 to detect these changes.
Archives of toxicology 2005;79(7):390-405.
2005: Bennard van Ravenzwaay; Werner Mellert; Klaus Deckardt; Karin Küttler
The comparative toxicology of 4-chloro-2-methylphenoxyacetic acid and its plant metabolite 4-chloro-2-carboxyphenoxyacetic acid in rats.
Regulatory toxicology and pharmacology : RTP 2005;42(1):47-54.
2005: Wolfgang Kaufmann; Werner Mellert; Bennard van Ravenzwaay; Robert LANDSIEDEL; A Poole
Effects of styrene and its metabolites on different lung compartments of the mouse--cell proliferation and histomorphology.
Regulatory toxicology and pharmacology : RTP 2005;42(1):24-36.
2004: Henk Tennekes; Wolfgang Kaufmann; Martina Dammann; Bennard van Ravenzwaay
The stability of historical control data for common neoplasms in laboratory rats and the implications for carcinogenic risk assessment.
Regulatory toxicology and pharmacology : RTP 2004;40(3):293-304.
2004: Armin Gamer; E Leibold; Klaus Deckardt; B Kittel; Wolfgang Kaufmann; Henk Tennekes; Bennard van Ravenzwaay
The effects of styrene on lung cells in female mice and rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2004;42(10):1655-67.
2004: Bennard van Ravenzwaay; E Leibold
A comparison between in vitro rat and human and in vivo rat skin absorption studies.
Human & experimental toxicology 2004;23(9):421-30.
2004: Werner Mellert; Klaus Deckardt; Christian Gembardt; I Zwirner-Baier; R Jäckh; Bennard van Ravenzwaay
Aniline: early indicators of toxicity in male rats and their relevance to spleen carcinogenicity.
Human & experimental toxicology 2004;23(8):379-89.
2004: Henk Tennekes; Christian Gembardt; Martina Dammann; Bennard van Ravenzwaay
The stability of historical control data for common neoplasms in laboratory rats: adrenal gland (medulla), mammary gland, liver, endocrine pancreas, and pituitary gland.
Regulatory toxicology and pharmacology : RTP 2004;40(1):18-27.
2004: Bennard van Ravenzwaay; E Leibold
The significance of in vitro rat skin absorption studies to human risk assessment.
Toxicology in vitro : an international journal published in association with BIBRA 2004;18(2):219-25.
2004: Werner Mellert; Wolfgang Kaufmann; R Rossbacher; Bennard van Ravenzwaay
Investigations on cell proliferation in B6C3F(1) mouse liver by diethanolamine.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2004;42(1):127-34.
2004: Bennard van Ravenzwaay; Geoff Pigott; E Leibold
Absorption, distribution, metabolism and excretion of 4-chloro-2-methylphenoxyacetic acid (MCPA) in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2004;42(1):115-25.
2003: Werner Mellert; Klaus Deckardt; J Walter; S Gfatter; Bennard van Ravenzwaay
Detection of endocrine-modulating effects of the antithyroid acting drug 6-propyl-2-thiouracil in rats, based on the "Enhanced OECD Test Guideline 407".
Regulatory toxicology and pharmacology : RTP 2003;38(3):368-77.
2003: Bennard van Ravenzwaay; Armin Gamer; E Leibold; Wolfgang Kaufmann
Effect of cytochrome P-450 inhibition on tetrahydrofuran-induced hepatocellular proliferation in female mice.
Archives of toxicology 2003;77(8):459-64.
2002: Armin Gamer; Jürgen Hellwig; Bennard van Ravenzwaay; J Heliwig
Developmental toxicity of oral n-butylamine hydrochloride and inhaled n-butylamine in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2002;40(12):1833-42.
2002: Armin Gamer; R Jaeckh; E Leibold; Wolfgang Kaufmann; Christian Gembardt; R Bahnemann; Bennard van Ravenzwaay
Investigations on cell proliferation and enzyme induction in male rat kidney and female mouse liver caused by tetrahydrofuran.
Toxicological sciences : an official journal of the Society of Toxicology 2002;70(1):140-9.
2002: Werner Mellert; Klaus Deckardt; Christian Gembardt; Stefan Schulte; Bennard van Ravenzwaay; R Slesinski
Thirteen-week oral toxicity study of synthetic lycopene products in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2002;40(11):1581-8.
2002: Bennard van Ravenzwaay; Henk Tennekes
A Wistar rat strain prone to spontaneous liver tumor development: implications for carcinogenic risk assessment.
Regulatory toxicology and pharmacology : RTP 2002;36(1):86-95.
2001: E M Bellet; Bennard van Ravenzwaay; Jürgen Hellwig; Geoff Pigott
Reproductive toxicity of MCPA (4-chloro-2-methylphenoxyacetic acid) in the rat.
International journal of toxicology 2001;20(1):29-38.
2000: Jürgen Hellwig; Bennard van Ravenzwaay; M Mayer; Christian Gembardt
Pre- and postnatal oral toxicity of vinclozolin in Wistar and Long-Evans rats.
Regulatory toxicology and pharmacology : RTP 2000;32(1):42-50.
1999: E M Bellet; Bennard van Ravenzwaay; Geoff Pigott; N Leeming
Chronic dietary toxicity and oncogenicity evaluation of MCPA (4-chloro-2-methylphenoxyacetic acid) in rodents.
Regulatory toxicology and pharmacology : RTP 1999;30(3):223-32.