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Jurphaas van Rietschoten

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Genes & Molecular Sequences

Amino Acid Sequences

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Sarrah M'barek; Ziad Fajloun; Sandrine Cestèle; Christiane Devaux; Pascal Mansuelle; Amor Mosbah; Besma Jouirou; Massimo Mantegazza; Jurphaas van Rietschoten; Mohamed El Ayeb; Hervé Rochat; Jean-Marc Sabatier; François Sampieri
First chemical synthesis of a scorpion alpha-toxin affecting sodium channels: the Aah I toxin of Androctonus australis hector.
Besma Jouirou; Amor Mosbah; Violeta Visan; Stephan Grissmer; Sarrah M'barek; Ziad Fajloun; Jurphaas van Rietschoten; Christiane Devaux; Hervé Rochat; Guy Lippens; Mohamed El Ayeb; Michel De Waard; Kamel Mabrouk; Jean-Marc Sabatier
Cobatoxin 1 from Centruroides noxius scorpion venom: chemical synthesis, three-dimensional structure in solution, pharmacology and docking on K+ channels.
Jean de Mareuil; Kamel Mabrouk; Evelyne Doria; Maxime Moulard; Stéphanie de Chasteigner; Razika Oughideni; Jurphaas van Rietschoten; Hervé Rochat; Michel De Waard; Jean-Marc Sabatier
Liposomal encapsulation enhances antiviral efficacy of SPC3 against human immunodeficiency virus type-1 infection in human lymphocytes.

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All Publications

2004: Sarrah M'barek; Ziad Fajloun; Sandrine Cestèle; Christiane Devaux; Pascal Mansuelle; Amor Mosbah; Besma Jouirou; Massimo Mantegazza; Jurphaas van Rietschoten; Mohamed El Ayeb; Hervé Rochat; Jean-Marc Sabatier; François Sampieri
First chemical synthesis of a scorpion alpha-toxin affecting sodium channels: the Aah I toxin of Androctonus australis hector.
Journal of peptide science : an official publication of the European Peptide Society 2004;10(11):666-77.
2004: Besma Jouirou; Amor Mosbah; Violeta Visan; Stephan Grissmer; Sarrah M'barek; Ziad Fajloun; Jurphaas van Rietschoten; Christiane Devaux; Hervé Rochat; Guy Lippens; Mohamed El Ayeb; Michel De Waard; Kamel Mabrouk; Jean-Marc Sabatier
Cobatoxin 1 from Centruroides noxius scorpion venom: chemical synthesis, three-dimensional structure in solution, pharmacology and docking on K+ channels.
The Biochemical journal 2004;377(Pt 1):37-49.
2002: Jean de Mareuil; Kamel Mabrouk; Evelyne Doria; Maxime Moulard; Stéphanie de Chasteigner; Razika Oughideni; Jurphaas van Rietschoten; Hervé Rochat; Michel De Waard; Jean-Marc Sabatier
Liposomal encapsulation enhances antiviral efficacy of SPC3 against human immunodeficiency virus type-1 infection in human lymphocytes.
Antiviral research 2002;54(3):175-88.
1999: C Lecomte; Gilles Ferrat; Ziad Fajloun; Jurphaas van Rietschoten; Hervé Rochat; Marie-France Martin-Eauclaire; Hervé Darbon; Jean-Marc Sabatier
Chemical synthesis and structure-activity relationships of Ts kappa, a novel scorpion toxin acting on apamin-sensitive SK channel.
The journal of peptide research : official journal of the American Peptide Society 1999;54(5):369-76.
1999: Maxime Moulard; Kamel Mabrouk; I Martin; Jurphaas van Rietschoten; Hervé Rochat; Jean-Marc Sabatier
V3 loop-derived peptide SPC3 inhibits infection of CD4- and galactosylceramide- cells by LAV-2/B.
The journal of peptide research : official journal of the American Peptide Society 1999;53(6):647-55.
1998: Rym Barbouche; Naziha Marrakchi; Kamel Mabrouk; Mohamed Naceur Krifi; Jurphaas van Rietschoten; Emmanuel Fenouillet; Mohamed El Ayeb; Hervé Rochat
Anti-platelet activity of the peptides composing the lebetin 1 family, a new class of inhibitors of platelet aggregation.
Toxicon : official journal of the International Society on Toxinology 1998;36(12):1939-47.
1998: Hervé Rochat; Riadh Kharrat; Jean-Marc Sabatier; Pascal Mansuelle; Marcel Crest; Marie-France Martin-Eauclaire; François Sampieri; Razika Oughideni; Kamel Mabrouk; Guy Jacquet; Jurphaas van Rietschoten; Mohamed El Ayeb
Maurotoxin, a four disulfide bridges scorpion toxin acting on K+ channels.
Toxicon : official journal of the International Society on Toxinology 1998;36(11):1609-11.
1998: C Lecomte; Jean-Marc Sabatier; Jurphaas van Rietschoten; Hervé Rochat
Synthetic peptides as tools to investigate the structure and pharmacology of potassium channel-acting short-chain scorpion toxins.
Biochimie 1998;80(2):151-4.
1997: E Blanc; Jean-Marc Sabatier; Riadh Kharrat; S Meunier; Mohamed El Ayeb; Jurphaas van Rietschoten; Hervé Darbon
Solution structure of maurotoxin, a scorpion toxin from Scorpio maurus, with high affinity for voltage-gated potassium channels.
Proteins 1997;29(3):321-33.
1997: Margarida Gairí; R Romi; I Fernández; Hervé Rochat; Marie-France Martin-Eauclaire; Jurphaas van Rietschoten; Miquel Pons; Ernest Giralt
3D structure of kaliotoxin: is residue 34 a key for channel selectivity?
Journal of peptide science : an official publication of the European Peptide Society 1997;3(4):314-9.
1997: Riadh Kharrat; Pascal Mansuelle; François Sampieri; Marcel Crest; Razika Oughideni; Jurphaas van Rietschoten; Marie-France Martin-Eauclaire; Hervé Rochat; Mohamed El Ayeb
Maurotoxin, a four disulfide bridge toxin from Scorpio maurus venom: purification, structure and action on potassium channels.
FEBS letters 1997;406(3):284-90.
1997: Ilhem Zenouaki; Riadh Kharrat; Jean-Marc Sabatier; Christiane Devaux; Habib Karoui; Jurphaas van Rietschoten; Mohamed El Ayeb; Hervé Rochat
In vivo protection against Androctonus australis hector scorpion toxin and venom by immunization with a synthetic analog of toxin II.
Vaccine 1997;15(2):187-94.
1996: Riadh Kharrat; Kamel Mabrouk; Marcel Crest; Hervé Darbon; Razika Oughideni; Marie-France Martin-Eauclaire; Guy Jacquet; Mohamed El Ayeb; Jurphaas van Rietschoten; Hervé Rochat; Jean-Marc Sabatier
Chemical synthesis and characterization of maurotoxin, a short scorpion toxin with four disulfide bridges that acts on K+ channels.
European journal of biochemistry / FEBS 1996;242(3):491-8.
1996: H Zerrouk; F Laraba-Djebari; V Fremont; A Meki; Hervé Darbon; Pascal Mansuelle; Razika Oughideni; Jurphaas van Rietschoten; Hervé Rochat; Marie-France Martin-Eauclaire
Characterization of PO1, a new peptide ligand of the apamin-sensitive Ca2+ activated K+ channel.
International journal of peptide and protein research 1996;48(6):514-21.
1996: Jean-Marc Sabatier; Kamel Mabrouk; Maxime Moulard; Hervé Rochat; Jurphaas van Rietschoten; Emmanuel Fenouillet
Anti-HIV activity of multibranched peptide constructs derived either from the cleavage sequence or from the transmembrane domain (gp41) of the human immunodeficiency virus type 1 envelope.
Virology 1996;223(2):406-8.
1996: Jean-Marc Sabatier; C Lecomte; Kamel Mabrouk; Hervé Darbon; Razika Oughideni; S Canarelli; Hervé Rochat; Marie-France Martin-Eauclaire; Jurphaas van Rietschoten
Synthesis and characterization of leiurotoxin I analogs lacking one disulfide bridge: evidence that disulfide pairing 3-21 is not required for full toxin activity.
Biochemistry 1996;35(33):10641-7.
1996: E Blanc; V Fremont; P Sizun; S Meunier; Jurphaas van Rietschoten; A Thevand; J M Bernassau; Hervé Darbon
Solution structure of P01, a natural scorpion peptide structurally analogous to scorpion toxins specific for apamin-sensitive potassium channel.
Proteins 1996;24(3):359-69.
1995: Christiane Devaux; M Knibiehler; M L Defendini; Kamel Mabrouk; Hervé Rochat; Jurphaas van Rietschoten; Daniel Baty; Claude Granier
Recombinant and chemical derivatives of apamin. Implication of post-transcriptional C-terminal amidation of apamin in biological activity.
European journal of biochemistry / FEBS 1995;231(3):544-50.
1995: Kamel Mabrouk; Jurphaas van Rietschoten; Hervé Rochat; E P Loret
Correlation of antiviral activity with beta-turn types for V3 synthetic multibranched peptides from HIV-1 gp120.
Biochemistry 1995;34(26):8294-8.
1995: Jean-Marc Sabatier; S Baghdiguian; Nouara Yahi; H Rochat; Jurphaas van Rietschoten; Jacques Fantini
SPC3, a nontoxic peptide inhibitor of HIV infection.
In vitro cellular & developmental biology. Animal 1995;31(6):415-8.
1995: Nouara Yahi; Jacques Fantini; S Baghdiguian; Kamel Mabrouk; Catherine Tamalet; H Rochat; Jurphaas van Rietschoten; Jean-Marc Sabatier
SPC3, a synthetic peptide derived from the V3 domain of human immunodeficiency virus type 1 (HIV-1) gp120, inhibits HIV-1 entry into CD4+ and CD4- cells by two distinct mechanisms.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):4867-71.
1995: Olivier Delezay; B Verrier; Kamel Mabrouk; Jurphaas van Rietschoten; Jacques Fantini; J Mauchamp; C Gerard
Characterization of an electrogenic sodium/glucose cotransporter in a human colon epithelial cell line.
Journal of cellular physiology 1995;163(1):120-8.
1994: F Laraba-Djebari; Christian Legros; Marcel Crest; B Céard; R Romi; Pascal Mansuelle; Guy Jacquet; Jurphaas van Rietschoten; M Gola; Hervé Rochat
The kaliotoxin family enlarged. Purification, characterization, and precursor nucleotide sequence of KTX2 from Androctonus australis venom.
The Journal of biological chemistry 1994;269(52):32835-43.
1994: I Fernández; R Romi; S Szendeffy; Marie-France Martin-Eauclaire; Hervé Rochat; Jurphaas van Rietschoten; Miquel Pons; Ernest Giralt
Kaliotoxin (1-37) shows structural differences with related potassium channel blockers.
Biochemistry 1994;33(47):14256-63.
1994: Nouara Yahi; Jacques Fantini; Kamel Mabrouk; Catherine Tamalet; P de Micco; Jurphaas van Rietschoten; H Rochat; Jean-Marc Sabatier
Multibranched V3 peptides inhibit human immunodeficiency virus infection in human lymphocytes and macrophages.
Journal of virology 1994;68(9):5714-20.
1994: Riadh Kharrat; I Zenouaki; Jean-Marc Sabatier; Z Belasfar; K Miled; Habib Karoui; Jurphaas van Rietschoten; Koussay Dellagi; Hervé Rochat; Mohamed El Ayeb
[Preparation of antivenins to scorpion venoms and a protection trials in animal models].
Archives de l'Institut Pasteur de Tunis 1994;71(3-4):473-6.
1994: E Vives; P Charneau; Jurphaas van Rietschoten; Hervé Rochat; Elmostafa Bahraoui
Effects of the Tat basic domain on human immunodeficiency virus type 1 transactivation, using chemically synthesized Tat protein and Tat peptides.
Journal of virology 1994;68(5):3343-53.
1994: Jean-Marc Sabatier; V Fremont; Kamel Mabrouk; Marcel Crest; Hervé Darbon; Hervé Rochat; Jurphaas van Rietschoten; Marie-France Martin-Eauclaire
Leiurotoxin I, a scorpion toxin specific for Ca(2+)-activated K+ channels. Structure-activity analysis using synthetic analogs.
International journal of peptide and protein research 1994;43(5):486-95.
1993: S Meunier; J M Bernassau; Jean-Marc Sabatier; Marie-France Martin-Eauclaire; Jurphaas van Rietschoten; C Cambillau; Hervé Darbon
Solution structure of P05-NH2, a scorpion toxin analog with high affinity for the apamin-sensitive potassium channel.
Biochemistry 1993;32(45):11969-76.
1993: Jacques Fantini; Nouara Yahi; Kamel Mabrouk; Jurphaas van Rietschoten; H Rochat; Jean-Marc Sabatier
Multi-branched peptides based on the HIV-1 V3 loop consensus motif inhibit HIV-1 and HIV-2 infection in CD4+ and CD4- cells.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1993;316(11):1381-7.
1993: M Tordjeman; G Fontan; V Rabillon; J Martin; C Trepo; A Hoffenbach; Kamel Mabrouk; Jean-Marc Sabatier; Jurphaas van Rietschoten; G Somme
Characterization of minor and major antigenic regions within the hepatitis B virus nucleocapsid.
Journal of medical virology 1993;41(3):221-9.
1993: Kamel Mabrouk; Maxime Moulard; J C Gluckman; R Romi; Hervé Rochat; Jurphaas van Rietschoten; Elmostafa Bahraoui
Evaluation of structure-antigenicity relationship of peptides from human immunodeficiency virus type 1 (HIV-1) p18 protein by circular dichroism.
Molecular immunology 1993;30(5):503-12.
1993: Jean-Marc Sabatier; H Zerrouk; Hervé Darbon; Kamel Mabrouk; A Benslimane; Hervé Rochat; Marie-France Martin-Eauclaire; Jurphaas van Rietschoten
P05, a new leiurotoxin I-like scorpion toxin: synthesis and structure-activity relationships of the alpha-amidated analog, a ligand of Ca(2+)-activated K+ channels with increased affinity.
Biochemistry 1993;32(11):2763-70.
1993: Abdelaziz Benjouad; Kamel Mabrouk; Maxime Moulard; J C Gluckman; Hervé Rochat; Jurphaas van Rietschoten; Jean-Marc Sabatier
Cytotoxic effect on lymphocytes of Tat from human immunodeficiency virus (HIV-1).
FEBS letters 1993;319(1-2):119-24.
1992: Kamel Mabrouk; Abdelaziz Benjouad; J C Gluckman; Hervé Rochat; Jurphaas van Rietschoten; Elmostafa Bahraoui
Specificity of anti-P25 antibodies produced against whole HIV-1 particles or soluble forms of the protein.
Molecular immunology 1992;29(11):1309-18.
1991: B Clerget-Raslain; Abdelaziz Benjouad; Jurphaas van Rietschoten; Luc Montagnier; Hervé Rochat; Elmostafa Bahraoui
Specificity of anti-peptide antibodies elicited against synthetic peptides mimicking conserved regions of HIV1 envelope glycoprotein.
Research in virology 1991;142(6):423-38.
1991: Kamel Mabrouk; Jurphaas van Rietschoten; E Vives; Hervé Darbon; Hervé Rochat; Jean-Marc Sabatier
Lethal neurotoxicity in mice of the basic domains of HIV and SIV Rev proteins. Study of these regions by circular dichroism.
FEBS letters 1991;289(1):13-7.
1991: E P Loret; E Vives; P Shing Ho; Hervé Rochat; Jurphaas van Rietschoten; W Curtis Johnson
Activating region of HIV-1 Tat protein: vacuum UV circular dichroism and energy minimization.
Biochemistry 1991;30(24):6013-23.
1991: CATHERINE LABBE-JULLIE; Claude Granier; Fernando Albericio; M L Defendini; B Ceard; Hervé Rochat; Jurphaas van Rietschoten
Binding and toxicity of apamin. Characterization of the active site.
European journal of biochemistry / FEBS 1991;196(3):639-45.
1990: Jean-Marc Sabatier; G Fontan; E Loret; Kamel Mabrouk; Hervé Rochat; Jean Claude Gluckman; Luc Montagnier; Claude Granier; Elmostafa Bahraoui; Jurphaas van Rietschoten
Large fragments of nef-protein and gp110 envelope glycoprotein from HIV-1. Synthesis, CD analysis and immunoreactivity.
International journal of peptide and protein research 1990;35(1):63-72.
1990: Luc Montagnier; D Berneman; Denise Guétard; Alain Blanchard; S Chamaret; V Rame; Jurphaas van Rietschoten; Kamel Mabrouk; Elmostafa Bahraoui
[Infectivity inhibition of HIV prototype strains by antibodies directed against a peptide sequence of mycoplasma].
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1990;311(12):425-30.
1990: M L Defendini; Elmostafa Bahraoui; CATHERINE LABBE-JULLIE; A Regnier-Vigouroux; Mohamed El Ayeb; Jurphaas van Rietschoten; Hervé Rochat; Claude Granier
Identification of antigenic residues on apamin recognized by polyclonal antibodies.
Molecular immunology 1990;27(1):37-44.
1989: A Regnier-Vigouroux; B Ceard; Jurphaas van Rietschoten; Claude Granier; M Pierres
Structural analysis of the interaction of apamin with Ia and its recognition by Ad- or Ab-restricted mouse T cells.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(10):3167-74.
1989: Elmostafa Bahraoui; B Clerget-Raslain; Claude Granier; Jurphaas van Rietschoten; Jean-Marc Sabatier; C Labbé-Julie; B Ceard; Hervé Rochat; Jean Claude Gluckman; Luc Montagnier
Accessibility of the highly conserved amino- and carboxy-terminal regions from HIV-1 external envelope glycoproteins.
AIDS research and human retroviruses 1989;5(4):451-63.
1989: Jean-Marc Sabatier; B Clerget-Raslain; G Fontan; Emmanuel Fenouillet; Hervé Rochat; Claude Granier; Jean Claude Gluckman; Jurphaas van Rietschoten; Luc Montagnier; Elmostafa Bahraoui
Use of synthetic peptides for the detection of antibodies against the nef regulating protein in sera of HIV-infected patients.
AIDS (London, England) 1989;3(4):215-20.
1989: Sophie Goyard; C Orlando; Jean-Marc Sabatier; E Labruyere; J d'Alayer; G Fontan; Jurphaas van Rietschoten; Michèle Mock; Antoine Danchin; Agnes Ullmann
Identification of a common domain in calmodulin-activated eukaryotic and bacterial adenylate cyclases.
Biochemistry 1989;28(5):1964-7.
1988: P Fourquet; Elmostafa Bahraoui; J C Fontecilla-Camps; Jurphaas van Rietschoten; H Rochat; C Granier
Immunochemistry of scorpion toxins. Synthesis and antigenic properties of a model of a loop region specific to alpha-toxins.
International journal of peptide and protein research 1988;32(2):81-8.
1988: Pascale Marchot; Pierre E Bougis; B Ceard; Jurphaas van Rietschoten; Hervé Rochat
Localization of the toxic site of Naja mossambica cardiotoxins: small synthetic peptides express an in vivo lethality.
Biochemical and biophysical research communications 1988;153(2):642-7.
1987: Jean-Marc Sabatier; Hervé Darbon; P Fourquet; H Rochat; Jurphaas van Rietschoten
Reduction and reoxidation of the neurotoxin II from the scorpion Androctonus australis Hector.
International journal of peptide and protein research 1987;30(1):125-34.
1986: Michael Seagar; CATHERINE LABBE-JULLIE; Claude Granier; A Goll; H Glossmann; Jurphaas van Rietschoten; François Couraud
Molecular structure of rat brain apamin receptor: differential photoaffinity labeling of putative K+ channel subunits and target size analysis.
Biochemistry 1986;25(14):4051-7.
1986: Elmostafa Bahraoui; Claude Granier; Jurphaas van Rietschoten; H Rochat; Mohamed El Ayeb
Specificity and neutralizing capacity of antibodies elicited by a synthetic peptide of scorpion toxin.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(9):3371-7.
1986: Elizabeth Trifilieff; B Luu; JL Nussbaum; Guy Roussel; A Espinosa de los Monteros; Jean-Marc Sabatier; Jurphaas van Rietschoten
A specific immunological probe for the major myelin proteolipid. Confirmation of a deletion in DM-20.
FEBS letters 1986;198(2):235-9.
1985: Michael Seagar; CATHERINE LABBE-JULLIE; Claude Granier; Jurphaas van Rietschoten; François Couraud
Photoaffinity labeling of components of the apamin-sensitive K+ channel in neuronal membranes.
The Journal of biological chemistry 1985;260(7):3895-8.
1984: Geneviève ROUGON; B Ceard; Jurphaas van Rietschoten; B Jordan; J Barbet
Induction with a synthetic peptide of antibodies to HLA class I C-terminal intracytoplasmic region.
Molecular immunology 1984;21(6):461-8.
1984: Mohamed El Ayeb; Elmostafa Bahraoui; Claude Granier; P Delori; Jurphaas van Rietschoten; Hervé Rochat
Immunochemistry of scorpion alpha-toxins: purification and characterization of two functionally independent IgG populations raised against toxin II of Androctonus australis Hector.
Molecular immunology 1984;21(3):223-32.
1983: CATHERINE LABBE-JULLIE; D Blanot; J L Morgat; P Kitabgi; F Checler; J P Vincent; C Granier; Jurphaas van Rietschoten
[Radioactive analogs of neurotensin. II. Preparation of tritiated neurotensin from a synthetic multi-unsaturated derivative].
Biochimie 1983;65(10):553-62.
1983: CATHERINE LABBE-JULLIE; P Kitabgi; C Granier; J P Vincent; Jurphaas van Rietschoten
[Radioactive analogs of neurotensin. I. Solid phase synthesis and biological characterization of Trp 11-neurotensin, a precursor of an iodized ligand].
Biochimie 1983;65(10):543-51.
1983: M Tessier; Fernando Albericio; Enrique Pedroso; Anna Grandas; Ramon Eritja; Ernest Giralt; Claude Granier; Jurphaas van Rietschoten
Amino-acids condensations in the preparation of N alpha-9-fluorenylmethyloxycarbonylamino-acids with 9-fluorenylmethylchloroformate.
International journal of peptide and protein research 1983;22(1):125-8.
1983: Pierre E Bougis; M Tessier; Jurphaas van Rietschoten; Hervé Rochat; J F Faucon; J Dufourcq
Are interactions with phospholipids responsible for pharmacological activities of cardiotoxins?
Molecular and cellular biochemistry 1983;55(1):49-64.
1982: Hervé Darbon; E Zlotkin; C Kopeyan; Jurphaas van Rietschoten; H Rochat
Covalent structure of the insect toxin of the North African scorpion Androctonus australis Hector.
International journal of peptide and protein research 1982;20(4):320-30.
1982: J Dufourcq; J F Faucon; E Bernard; M Pezolet; M Tessier; Jurphaas van Rietschoten; P Delori; Hervé Rochat
Structure-function relationships for cardiotoxins interacting with phospholipids.
Toxicon : official journal of the International Society on Toxinology 1982;20(1):165-74.
1981: P Delori; Jurphaas van Rietschoten; Hervé Rochat
Scorpion venoms and neurotoxins: an immunological study.
Toxicon : official journal of the International Society on Toxinology 1981;19(3):393-407.