Koen Van Rompay

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Rosati Margherita; Bergamaschi Cristina; Valentin Antonio; Kulkarni Viraj; Jalah Rashmi; Alicea Candido; Patel Vainav; von Gegerfelt Agneta S; Montefiori David C; Venzon David J; Khan Amir S; Draghia-Akli Ruxandra; Van Rompay Koen K A; Felber Barbara K; Pavlakis George N
DNA vaccination in rhesus macaques induces potent immune responses and decreases acute and chronic viremia after SIVmac251 challenge.
Durand-Gasselin Lucie; Van Rompay Koen K A; Vela Jennifer E; Henne Ilana N; Lee William A; Rhodes Gerry R; Ray Adrian S
Nucleotide analogue prodrug tenofovir disoproxil enhances lymphoid cell loading following oral administration in monkeys.
Van Rompay Koen K A; Durand-Gasselin Lucie; Brignolo Laurie L; Ray Adrian S; Abel Kristina; Cihlar Tomas; Spinner Abigail; Jerome Christopher; Moore Joseph; Kearney Brian P; Marthas Marta L; Reiser Hans; Bischofberger Norbert
Chronic administration of tenofovir to rhesus macaques from infancy through adulthood and pregnancy: summary of pharmacokinetics and biological and virological effects.

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2009: Rosati Margherita; Bergamaschi Cristina; Valentin Antonio; Kulkarni Viraj; Jalah Rashmi; Alicea Candido; Patel Vainav; von Gegerfelt Agneta S; Montefiori David C; Venzon David J; Khan Amir S; Draghia-Akli Ruxandra; Van Rompay Koen K A; Felber Barbara K; Pavlakis George N
DNA vaccination in rhesus macaques induces potent immune responses and decreases acute and chronic viremia after SIVmac251 challenge.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(37):15831-6.
2009: Durand-Gasselin Lucie; Van Rompay Koen K A; Vela Jennifer E; Henne Ilana N; Lee William A; Rhodes Gerry R; Ray Adrian S
Nucleotide analogue prodrug tenofovir disoproxil enhances lymphoid cell loading following oral administration in monkeys.
Molecular pharmaceutics 2009;6(4):1145-51.
2008: Van Rompay Koen K A; Durand-Gasselin Lucie; Brignolo Laurie L; Ray Adrian S; Abel Kristina; Cihlar Tomas; Spinner Abigail; Jerome Christopher; Moore Joseph; Kearney Brian P; Marthas Marta L; Reiser Hans; Bischofberger Norbert
Chronic administration of tenofovir to rhesus macaques from infancy through adulthood and pregnancy: summary of pharmacokinetics and biological and virological effects.
Antimicrobial agents and chemotherapy 2008;52(9):3144-60.
2007: Van Rompay Koen K A; Johnson Jeffrey A; Blackwood Emily J; Singh Raman P; Lipscomb Jonathan; Matthews Timothy B; Marthas Marta L; Pedersen Niels C; Bischofberger Norbert; Heneine Walid; North Thomas W
Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection.
Retrovirology 2007;4():25.
2006: Florese Ruth H; Van Rompay Koen K A; Aldrich Kris; Forthal Donald N; Landucci Gary; Mahalanabis Madhumita; Haigwood Nancy; Venzon David; Kalyanaraman Vaniambadi S; Marthas Marta L; Robert-Guroff Marjorie
Evaluation of passively transferred, nonneutralizing antibody-dependent cellular cytotoxicity-mediating IgG in protection of neonatal rhesus macaques against oral SIVmac251 challenge.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(6):4028-36.
2006: Forthal Donald N; Landucci Gary; Cole Kelly Stefano; Marthas Marta; Becerra Juan C; Van Rompay Koen
Rhesus macaque polyclonal and monoclonal antibodies inhibit simian immunodeficiency virus in the presence of human or autologous rhesus effector cells.
Journal of virology 2006;80(18):9217-25.
2006: Van Rompay Koen K A; Kearney Brian P; Sexton Jonathan J; Colón Roxana; Lawson Jonathan R; Blackwood Emily J; Lee William A; Bischofberger Norbert; Marthas Marta L
Evaluation of oral tenofovir disoproxil fumarate and topical tenofovir GS-7340 to protect infant macaques against repeated oral challenges with virulent simian immunodeficiency virus.
Journal of acquired immune deficiency syndromes (1999) 2006;43(1):6-14.
2006: Van Rompay Koen K A; Singh Raman P; Heneine Walid; Johnson Jeffrey A; Montefiori David C; Bischofberger Norbert; Marthas Marta L
Structured treatment interruptions with tenofovir monotherapy for simian immunodeficiency virus-infected newborn macaques.
Journal of virology 2006;80(13):6399-410.
2006: Abel Kristina; Pahar Bapi; Van Rompay Koen K A; Fritts Linda; Sin Clarissa; Schmidt Kimberli; Colón Roxana; McChesney Mike; Marthas Marta L
Rapid virus dissemination in infant macaques after oral simian immunodeficiency virus exposure in the presence of local innate immune responses.
Journal of virology 2006;80(13):6357-67.
2006: von Gegerfelt Agneta S; Alicea Candido; Valentin Antonio; Morrow Matthew; van Rompay Koen K A; Ayash-Rashkovsky Mila; Markham Phillip; Else James G; Marthas Marta L; Pavlakis George N; Ruprecht Ruth M; Felber Barbara K
Long lasting control and lack of pathogenicity of the attenuated Rev-independent SIV in rhesus macaques.
AIDS research and human retroviruses 2006;22(6):516-28.
2006: Van Rompay Koen K A; Blackwood Emily J; Landucci Gary; Forthal Don; Marthas Marta L
Role of CD8+ cells in controlling replication of nonpathogenic Simian Immunodeficiency Virus SIVmac1A11.
Virology journal 2006;3():22.
2005: North Thomas W; Van Rompay Koen K A; Higgins Joanne; Matthews Timothy B; Wadford Debra A; Pedersen Niels C; Schinazi Raymond F
Suppression of virus load by highly active antiretroviral therapy in rhesus macaques infected with a recombinant simian immunodeficiency virus containing reverse transcriptase from human immunodeficiency virus type 1.
Journal of virology 2005;79(12):7349-54.
2005: Van Rompay Koen K A; Hamilton Marta; Kearney Brian; Bischofberger Norbert
Pharmacokinetics of tenofovir in breast milk of lactating rhesus macaques.
Antimicrobial agents and chemotherapy 2005;49(5):2093-4.
2005: Van Rompay Koen K A
Antiretroviral drug studies in nonhuman primates: a valid animal model for innovative drug efficacy and pathogenesis experiments.
AIDS reviews 2005;7(2):67-83.
2005: Van Rompay Koen K A; Abel Kristina; Lawson Jonathan R; Singh Raman P; Schmidt Kimberli A; Evans Thomas; Earl Patricia; Harvey Danielle; Franchini Genoveffa; Tartaglia James; Montefiori David; Hattangadi Shilpa; Moss Bernard; Marthas Marta L
Attenuated poxvirus-based simian immunodeficiency virus (SIV) vaccines given in infancy partially protect infant and juvenile macaques against repeated oral challenge with virulent SIV.
Journal of acquired immune deficiency syndromes (1999) 2005;38(2):124-34.
2005: Greenier Jennifer L; Van Rompay Koen K A; Montefiori David; Earl Patricia; Moss Bernard; Marthas Marta L
Simian immunodeficiency virus (SIV) envelope quasispecies transmission and evolution in infant rhesus macaques after oral challenge with uncloned SIVmac251: increased diversity is associated with neutralizing antibodies and improved survival in previously immunized animals.
Virology journal 2005;2():11.
2004: Van Rompay Koen K A
Motor-biking through rural India on an HIV mission.
AIDS (London, England) 2004;18(16):N13-6.
2004: Van Rompay Koen K A; Marthas Marta L; Bischofberger Norbert
Tenofovir primes rhesus macaque cells in vitro for enhanced interleukin-12 secretion.
Antiviral research 2004;63(2):133-8.
2004: Van Rompay Koen K A; Singh Raman P; Brignolo Laurie L; Lawson Jonathan R; Schmidt Kimberli A; Pahar Bapi; Canfield Don R; Tarara Ross P; Sodora Donald L; Bischofberger Norbert; Marthas Marta L
The clinical benefits of tenofovir for simian immunodeficiency virus-infected macaques are larger than predicted by its effects on standard viral and immunologic parameters.
Journal of acquired immune deficiency syndromes (1999) 2004;36(4):900-14.
2004: Belshe Robert; Franchini Genoveffa; Girard Marc P; Gotch Frances; Kaleebu Pontiano; Marthas Marta L; McChesney Michael B; McCullough Rose; Mhalu Fred; Salmon-Ceron Dominique; Sekaly Rafick-Pierre; van Rompay Koen; Verrier Bernard; Wahren Britta; Weissenbacher Mercedes
Support for the RV144 HIV vaccine trial.
Science (New York, N.Y.) 2004;305(5681):177-80; author reply 177-80.
2004: Bulterys Marc; Fowler Mary Glenn; Van Rompay Koen K; Kourtis Athena P
Prevention of mother-to-child transmission of HIV-1 through breast-feeding: past, present, and future.
The Journal of infectious diseases 2004;189(12):2149-53.
2004: Van Rompay Koen K A; Singh Raman P; Pahar Bapi; Sodora Donald L; Wingfield Casey; Lawson Jonathan R; Marthas Marta L; Bischofberger Norbert
CD8+-cell-mediated suppression of virulent simian immunodeficiency virus during tenofovir treatment.
Journal of virology 2004;78(10):5324-37.
2004: Van Rompay Koen K A; Brignolo Laurie L; Meyer Dennis J; Jerome Christopher; Tarara Ross; Spinner Abigail; Hamilton Marta; Hirst Linda L; Bennett David R; Canfield Don R; Dearman Trish G; Von Morgenland Wilhelm; Allen Phil C; Valverde Celia; Castillo Alesha B; Martin R Bruce; Samii Valerie F; Bendele Ray; Desjardins John; Marthas Marta L; Pedersen Niels C; Bischofberger Norbert
Biological effects of short-term or prolonged administration of 9-[2-(phosphonomethoxy)propyl]adenine (tenofovir) to newborn and infant rhesus macaques.
Antimicrobial agents and chemotherapy 2004;48(5):1469-87.
2004: Bernardin Flavien; Magierowska Magdalena; Dandekar Satya; Van Rompay Koen K A; Delwart Eric L
Number of CD4+ and CD8+ T-cell CDR3 clonotypes expanding during acute infection of macaques with simian immunodeficiency virus.
Virology 2004;322(1):105-17.
2004: Magierowska Magdalena; Bernardin Flavien; Garg Seema; Staprans Silvija; Miller Michael D; Van Rompay Koen K A; Delwart Eric L
Highly uneven distribution of tenofovir-selected simian immunodeficiency virus in different anatomical sites of rhesus macaques.
Journal of virology 2004;78(5):2434-44.
2004: Gaillard Philippe; Fowler Mary-Glenn; Dabis Francois; Coovadia Hoosen; Van Der Horst Charles; Van Rompay Koen; Ruff Andrea; Taha Taha; Thomas Tim; De Vincenzi Isabelle; Newell Marie-Louise;
Use of antiretroviral drugs to prevent HIV-1 transmission through breast-feeding: from animal studies to randomized clinical trials.
Journal of acquired immune deficiency syndromes (1999) 2004;35(2):178-87.
2004: Safrit Jeffrey T; Ruprecht Ruth; Ferrantelli Flavia; Xu Weidong; Kitabwalla Moiz; Van Rompay Koen; Marthas Marta; Haigwood Nancy; Mascola John R; Luzuriaga Katherine; Jones Samuel Adeniyi; Mathieson Bonnie J; Newell Marie-Louise;
Immunoprophylaxis to prevent mother-to-child transmission of HIV-1.
Journal of acquired immune deficiency syndromes (1999) 2004;35(2):169-77.
2003: Murry Jeffrey P; Higgins Joanne; Matthews Timothy B; Huang Victoria Y; Van Rompay Koen K A; Pedersen Niels C; North Thomas W
Reversion of the M184V mutation in simian immunodeficiency virus reverse transcriptase is selected by tenofovir, even in the presence of lamivudine.
Journal of virology 2003;77(2):1120-30.
2003: Van Rompay Koen K A; Greenier Jennifer L; Cole Kelly Stefano; Earl Patricia; Moss Bernard; Steckbeck Jonathan D; Pahar Bapi; Rourke Tracy; Montelaro Ronald C; Canfield Don R; Tarara Ross P; Miller Christopher; McChesney Michael B; Marthas Marta L
Immunization of newborn rhesus macaques with simian immunodeficiency virus (SIV) vaccines prolongs survival after oral challenge with virulent SIVmac251.
Journal of virology 2003;77(1):179-90.
2002: Van Rompay Koen K A; Schmidt Kimberli A; Lawson Jonathan R; Singh Raman; Bischofberger Norbert; Marthas Marta L
Topical administration of low-dose tenofovir disoproxil fumarate to protect infant macaques against multiple oral exposures of low doses of simian immunodeficiency virus.
The Journal of infectious diseases 2002;186(10):1508-13.
2002: Van Rompay Koen K A; Matthews Tim B; Higgins Joanne; Canfield Don R; Tarara Ross P; Wainberg Mark A; Schinazi Raymond F; Pedersen Niels C; North Thomas W
Virulence and reduced fitness of simian immunodeficiency virus with the M184V mutation in reverse transcriptase.
Journal of virology 2002;76(12):6083-92.
2001: Van Rompay K K; McChesney M B; Aguirre N L; Schmidt K A; Bischofberger N; Marthas M L
Two low doses of tenofovir protect newborn macaques against oral simian immunodeficiency virus infection.
The Journal of infectious diseases 2001;184(4):429-38.
2000: Van Rompay K K; Miller M D; Marthas M L; Margot N A; Dailey P J; Canfield D R; Tarara R P; Cherrington J M; Aguirre N L; Bischofberger N; Pedersen N C
Prophylactic and therapeutic benefits of short-term 9-[2-(R)-(phosphonomethoxy)propyl]adenine (PMPA) administration to newborn macaques following oral inoculation with simian immunodeficiency virus with reduced susceptibility to PMPA.
Journal of virology 2000;74(4):1767-74.
1999: Van Rompay K K; Cherrington J M; Marthas M L; Lamy P D; Dailey P J; Canfield D R; Tarara R P; Bischofberger N; Pedersen N C
9-[2-(Phosphonomethoxy)propyl]adenine (PMPA) therapy prolongs survival of infant macaques inoculated with simian immunodeficiency virus with reduced susceptibility to PMPA.
Antimicrobial agents and chemotherapy 1999;43(4):802-12.
1999: van Rompay K K; Dailey P J; Tarara R P; Canfield D R; Aguirre N L; Cherrington J M; Lamy P D; Bischofberger N; Pedersen N C; Marthas M L
Early short-term 9-[2-(R)-(phosphonomethoxy)propyl]adenine treatment favorably alters the subsequent disease course in simian immunodeficiency virus-infected newborn Rhesus macaques.
Journal of virology 1999;73(4):2947-55.
1998: Van Rompay K K; Berardi C J; Aguirre N L; Bischofberger N; Lietman P S; Pedersen N C; Marthas M L
Two doses of PMPA protect newborn macaques against oral simian immunodeficiency virus infection.
AIDS (London, England) 1998;12(9):F79-83.
1998: Van Rompay K K; Marthas M L; Lifson J D; Berardi C J; Vasquez G M; Agatep E; Dehqanzada Z A; Cundy K C; Bischofberger N; Pedersen N C
Administration of 9-[2-(phosphonomethoxy)propyl]adenine (PMPA) for prevention of perinatal simian immunodeficiency virus infection in rhesus macaques.
AIDS research and human retroviruses 1998;14(9):761-73.
1998: Van Rompay K K; Berardi C J; Dillard-Telm S; Tarara R P; Canfield D R; Valverde C R; Montefiori D C; Cole K S; Montelaro R C; Miller C J; Marthas M L
Passive immunization of newborn rhesus macaques prevents oral simian immunodeficiency virus infection.
The Journal of infectious diseases 1998;177(5):1247-59.
1997: Van Rompay K K; Marthas M L
Antiretroviral drug trials.
Science (New York, N.Y.) 1997;276(5318):1482-4.
1997: Van Rompay K K; Greenier J L; Marthas M L; Otsyula M G; Tarara R P; Miller C J; Pedersen N C
A zidovudine-resistant simian immunodeficiency virus mutant with a Q151M mutation in reverse transcriptase causes AIDS in newborn macaques.
Antimicrobial agents and chemotherapy 1997;41(2):278-83.
1996: Van Rompay K K; Cherrington J M; Marthas M L; Berardi C J; Mulato A S; Spinner A; Tarara R P; Canfield D R; Telm S; Bischofberger N; Pedersen N C
9-[2-(Phosphonomethoxy)propyl]adenine therapy of established simian immunodeficiency virus infection in infant rhesus macaques.
Antimicrobial agents and chemotherapy 1996;40(11):2586-91.
1996: Otsyula M G; Miller C J; Tarantal A F; Marthas M L; Greene T P; Collins J R; van Rompay K K; McChesney M B
Fetal or neonatal infection with attenuated simian immunodeficiency virus results in protective immunity against oral challenge with pathogenic SIVmac251.
Virology 1996;222(1):275-8.
1996: Van Rompay K K; Otsyula M G; Tarara R P; Canfield D R; Berardi C J; McChesney M B; Marthas M L
Vaccination of pregnant macaques protects newborns against mucosal simian immunodeficiency virus infection.
The Journal of infectious diseases 1996;173(6):1327-35.
1996: Otsyula M G; Miller C J; Marthas M L; Van Rompay K K; Collins J R; Pedersen N C; McChesney M B
Virus-induced immunosuppression is linked to rapidly fatal disease in infant rhesus macaques infected with simian immunodeficiency virus.
Pediatric research 1996;39(4 Pt 1):630-5.
1995: Van Rompay K K; Spinner A; Otsyula M; McChesney M B; Marthas M L
Attenuated retrovirus vaccines and AIDS.
Science (New York, N.Y.) 1995;270(5239):1218-9; author reply 1220-2.
1995: Marthas M L; van Rompay K K; Otsyula M; Miller C J; Canfield D R; Pedersen N C; McChesney M B
Viral factors determine progression to AIDS in simian immunodeficiency virus-infected newborn rhesus macaques.
Journal of virology 1995;69(7):4198-205.
1995: Van Rompay K; Marthas M L
"The Duesberg phenomenon": what does it mean?
Science (New York, N.Y.) 1995;267(5195):157.
1995: Van Rompay K K; Otsyula M G; Marthas M L; Miller C J; McChesney M B; Pedersen N C
Immediate zidovudine treatment protects simian immunodeficiency virus-infected newborn macaques against rapid onset of AIDS.
Antimicrobial agents and chemotherapy 1995;39(1):125-31.
1994: Lohman B L; McChesney M B; Miller C J; McGowan E; Joye S M; Van Rompay K K; Reay E; Antipa L; Pedersen N C; Marthas M L
A partially attenuated simian immunodeficiency virus induces host immunity that correlates with resistance to pathogenic virus challenge.
Journal of virology 1994;68(11):7021-9.
1994: van Rompay K K; Marthas M L; Pedersen N C
Prophylactic ZDV dosing frequency in macaques.
Journal of acquired immune deficiency syndromes 1994;7(6):627-9.
1993: Marthas M L; Ramos R A; Lohman B L; Van Rompay K K; Unger R E; Miller C J; Banapour B; Pedersen N C; Luciw P A
Viral determinants of simian immunodeficiency virus (SIV) virulence in rhesus macaques assessed by using attenuated and pathogenic molecular clones of SIVmac.
Journal of virology 1993;67(10):6047-55.
1992: Van Rompay K K; Marthas M L; Ramos R A; Mandell C P; McGowan E K; Joye S M; Pedersen N C
Simian immunodeficiency virus (SIV) infection of infant rhesus macaques as a model to test antiretroviral drug prophylaxis and therapy: oral 3'-azido-3'-deoxythymidine prevents SIV infection.
Antimicrobial agents and chemotherapy 1992;36(11):2381-6.
1992: Unger R E; Marthas M L; Lackner A A; Pratt-Lowe E; Lohman B L; Van Rompay K; Luciw P A
Detection of simian immunodeficiency virus DNA in macrophages from infected rhesus macaques.
Journal of medical primatology 1992;21(2-3):74-81.

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Koen Van Rompay

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