Username

Password

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Nico van Rooijen

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

Anatomy

Chemicals & Drugs

Disorders

Animal Disease Models

Physiology

Cell Movement

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Koh Andrew Y; Priebe Gregory P; Ray Christopher; Van Rooijen Nico; Pier Gerald B
Inescapable need for neutrophils as mediators of cellular innate immunity to acute Pseudomonas aeruginosa pneumonia.
Kurowska-Stolarska Mariola; Stolarski Bartosz; Kewin Peter; Murphy Grace; Corrigan Christopher J; Ying Sun; Pitman Nick; Mirchandani Ananda; Rana Batika; van Rooijen Nico; Shepherd Malcolm; McSharry Charlie; McInnes Iain B; Xu Damo; Liew Foo Y
IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation.
Lee Pui Y; Li Yi; Kumagai Yutaro; Xu Yuan; Weinstein Jason S; Kellner Erinn S; Nacionales Dina C; Butfiloski Edward J; van Rooijen Nico; Akira Shizuo; Sobel Eric S; Satoh Minoru; Reeves Westley H
Type I interferon modulates monocyte recruitment and maturation in chronic inflammation.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Nico van Rooijen (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Koh Andrew Y; Priebe Gregory P; Ray Christopher; Van Rooijen Nico; Pier Gerald B
Inescapable need for neutrophils as mediators of cellular innate immunity to acute Pseudomonas aeruginosa pneumonia.
Infection and immunity 2009;77(12):5300-10.
2009: Kurowska-Stolarska Mariola; Stolarski Bartosz; Kewin Peter; Murphy Grace; Corrigan Christopher J; Ying Sun; Pitman Nick; Mirchandani Ananda; Rana Batika; van Rooijen Nico; Shepherd Malcolm; McSharry Charlie; McInnes Iain B; Xu Damo; Liew Foo Y
IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(10):6469-77.
2009: Lee Pui Y; Li Yi; Kumagai Yutaro; Xu Yuan; Weinstein Jason S; Kellner Erinn S; Nacionales Dina C; Butfiloski Edward J; van Rooijen Nico; Akira Shizuo; Sobel Eric S; Satoh Minoru; Reeves Westley H
Type I interferon modulates monocyte recruitment and maturation in chronic inflammation.
The American journal of pathology 2009;175(5):2023-33.
2009: Chung Eui-Sang; Chauhan Sunil Kumar; Jin Yiping; Nakao Shintaro; Hafezi-Moghadam Ali; van Rooijen Nico; Zhang Qiang; Chen Lu; Dana Reza
Contribution of macrophages to angiogenesis induced by vascular endothelial growth factor receptor-3-specific ligands.
The American journal of pathology 2009;175(5):1984-92.
2009: Clementi Alicia H; Gaudy Allison M; van Rooijen Nico; Pierce Robert H; Mooney Robert A
Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling.
Biochimica et biophysica acta 2009;1792(11):1062-72.
2009: Wernli Gwenaelle; Hasan Wohaib; Bhattacherjee Aritra; van Rooijen Nico; Smith Peter G
Macrophage depletion suppresses sympathetic hyperinnervation following myocardial infarction.
Basic research in cardiology 2009;104(6):681-93.
2009: Zhao Jincun; Zhao Jingxian; Van Rooijen Nico; Perlman Stanley
Evasion by stealth: inefficient immune activation underlies poor T cell response and severe disease in SARS-CoV-infected mice.
PLoS pathogens 2009;5(10):e1000636.
2009: Ghulam Muhammad A K M; Candolfi Marianela; King Gwendalyn D; Yagiz Kader; Foulad David; Mineharu Yohei; Kroeger Kurt M; Treuer Katherine A; Nichols W Stephen; Sanderson Nicholas S; Yang Jieping; Khayznikov Maksim; Van Rooijen Nico; Lowenstein Pedro R; Castro Maria G
Antiglioma immunological memory in response to conditional cytotoxic/immune-stimulatory gene therapy: humoral and cellular immunity lead to tumor regression.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(19):6113-27.
2009: McKee Amy S; Munks Michael W; MacLeod Megan K L; Fleenor Courtney J; Van Rooijen Nico; Kappler John W; Marrack Philippa
Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(7):4403-14.
2009: Fink Katja; Ng Cedrig; Nkenfou Celine; Vasudevan Subhash G; van Rooijen Nico; Schul Wouter
Depletion of macrophages in mice results in higher dengue virus titers and highlights the role of macrophages for virus control.
European journal of immunology 2009;39(10):2809-21.
2009: Gupta Rohini; Van Rooijen Nico; Sefton Michael V
Fate of endothelialized modular constructs implanted in an omental pouch in nude rats.
Tissue engineering. Part A 2009;15(10):2875-87.
2009: Kirby Alun C; Beattie Lynette; Maroof Asher; van Rooijen Nico; Kaye Paul M
SIGNR1-negative red pulp macrophages protect against acute streptococcal sepsis after Leishmania donovani-induced loss of marginal zone macrophages.
The American journal of pathology 2009;175(3):1107-15.
2009: Holub Martin; Cheng Chao-Wen; Mott Stephanie; Wintermeyer Philip; van Rooijen Nico; Gregory Stephen H
Neutrophils sequestered in the liver suppress the proinflammatory response of Kupffer cells to systemic bacterial infection.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(5):3309-16.
2009: Ye Zhan; Kerschen Edward J; Cohen Donald A; Kaplan Alan M; van Rooijen Nico; Straley Susan C
Gr1+ cells control growth of YopM-negative yersinia pestis during systemic plague.
Infection and immunity 2009;77(9):3791-806.
2009: Woodman Michael E; Cooley Anne E; Avdiushko Rita; Bowman Amy; Botto Marina; Wooten R Mark; van Rooijen Nico; Cohen Donald A; Stevenson Brian
Roles for phagocytic cells and complement in controlling relapsing fever infection.
Journal of leukocyte biology 2009;86(3):727-36.
2009: Mircescu Monica M; Lipuma Lauren; van Rooijen Nico; Pamer Eric G; Hohl Tobias M
Essential role for neutrophils but not alveolar macrophages at early time points following Aspergillus fumigatus infection.
The Journal of infectious diseases 2009;200(4):647-56.
2009: Imamura Michiko; Tsutsui Hiroko; Yasuda Koubun; Uchiyama Ryosuke; Yumikura-Futatsugi Shizue; Mitani Keiko; Hayashi Shuhei; Akira Shizuo; Taniguchi Shun-Ichiro; Van Rooijen Nico; Tschopp Jurg; Yamamoto Tetsuya; Fujimoto Jiro; Nakanishi Kenji
Contribution of TIR domain-containing adapter inducing IFN-beta-mediated IL-18 release to LPS-induced liver injury in mice.
Journal of hepatology 2009;51(2):333-41.
2009: Wan Hui; Coppens Jojanneke M C; van Helden-Meeuwsen Cornelia G; Leenen Pieter J M; van Rooijen Nico; Khan Nisar A; Kiekens Rebecca C M; Benner Robbert; Versnel Marjan A
Chorionic gonadotropin alleviates thioglycollate-induced peritonitis by affecting macrophage function.
Journal of leukocyte biology 2009;86(2):361-70.
2009: Majeti Ravindra; Chao Mark P; Alizadeh Ash A; Pang Wendy W; Jaiswal Siddhartha; Gibbs Kenneth D; van Rooijen Nico; Weissman Irving L
CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells.
Cell 2009;138(2):286-99.
2009: Jaiswal Siddhartha; Jamieson Catriona H M; Pang Wendy W; Park Christopher Y; Chao Mark P; Majeti Ravindra; Traver David; van Rooijen Nico; Weissman Irving L
CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis.
Cell 2009;138(2):271-85.
2009: Markovic D S; Vinnakota K; Chirasani S; Synowitz M; Raguet H; Stock K; Sliwa M; Lehmann S; Kälin R; van Rooijen N; Holmbeck K; Heppner F L; Kiwit J; Matyash V; Lehnardt S; Kaminska B; Glass R; Kettenmann H
Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(30):12530-5.
2009: Betting David J; Yamada Reiko E; Kafi Kamran; Said Jonathan; van Rooijen Nico; Timmerman John M
Intratumoral but not systemic delivery of CpG oligodeoxynucleotide augments the efficacy of anti-CD20 monoclonal antibody therapy against B cell lymphoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009;32(6):622-31.
2009: Perrigoue Jacqueline G; Saenz Steven A; Siracusa Mark C; Allenspach Eric J; Taylor Betsy C; Giacomin Paul R; Nair Meera G; Du Yurong; Zaph Colby; van Rooijen Nico; Comeau Michael R; Pearce Edward J; Laufer Terri M; Artis David
MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity.
Nature immunology 2009;10(7):697-705.
2009: Seki Ekihiro; de Minicis Samuele; Inokuchi Sayaka; Taura Kojiro; Miyai Katsumi; van Rooijen Nico; Schwabe Robert F; Brenner David A
CCR2 promotes hepatic fibrosis in mice.
Hepatology (Baltimore, Md.) 2009;50(1):185-97.
2009: Alba Raul; Bradshaw Angela C; Parker Alan L; Bhella David; Waddington Simon N; Nicklin Stuart A; van Rooijen Nico; Custers Jerome; Goudsmit Jaap; Barouch Dan H; McVey John H; Baker Andrew H
Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer.
Blood 2009;114(5):965-71.
2009: Lu Peirong; Li Longbiao; Liu Gaoqin; van Rooijen Nico; Mukaida Naofumi; Zhang Xueguang
Opposite roles of CCR2 and CX3CR1 macrophages in alkali-induced corneal neovascularization.
Cornea 2009;28(5):562-9.
2009: Donnelly Dustin J; Gensel John C; Ankeny Daniel P; van Rooijen Nico; Popovich Phillip G
An efficient and reproducible method for quantifying macrophages in different experimental models of central nervous system pathology.
Journal of neuroscience methods 2009;181(1):36-44.
2009: Horst Andrea K; Bickert Thomas; Brewig Nancy; Ludewig Peter; van Rooijen Nico; Schumacher Udo; Beauchemin Nicole; Ito Wulf D; Fleischer Bernhard; Wagener Christoph; Ritter Uwe
CEACAM1+ myeloid cells control angiogenesis in inflammation.
Blood 2009;113(26):6726-36.
2009: Cawood Ryan; Chen Hannah H; Carroll Fionnadh; Bazan-Peregrino Miriam; van Rooijen Nico; Seymour Leonard W
Use of tissue-specific microRNA to control pathology of wild-type adenovirus without attenuation of its ability to kill cancer cells.
PLoS pathogens 2009;5(5):e1000440.
2009: Machnik Agnes; Neuhofer Wolfgang; Jantsch Jonathan; Dahlmann Anke; Tammela Tuomas; Machura Katharina; Park Joon-Keun; Beck Franz-Xaver; Müller Dominik N; Derer Wolfgang; Goss Jennifer; Ziomber Agata; Dietsch Peter; Wagner Hubertus; van Rooijen Nico; Kurtz Armin; Hilgers Karl F; Alitalo Kari; Eckardt Kai-Uwe; Luft Friedrich C; Kerjaschki Dontscho; Titze Jens
Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism.
Nature medicine 2009;15(5):545-52.
2009: Wilson Michael R; O'Dea Kieran P; Zhang Da; Shearman Alexander D; van Rooijen Nico; Takata Masao
Role of lung-marginated monocytes in an in vivo mouse model of ventilator-induced lung injury.
American journal of respiratory and critical care medicine 2009;179(10):914-22.
2009: Campion Sarah N; Tatis-Rios Cristina; Augustine Lisa M; Goedken Michael J; van Rooijen Nico; Cherrington Nathan J; Manautou José E
Effect of allyl alcohol on hepatic transporter expression: zonal patterns of expression and role of Kupffer cell function.
Toxicology and applied pharmacology 2009;236(1):49-58.
2009: Hernandez Lorena; Smirnova Tatiana; Kedrin Dmitriy; Wyckoff Jeffrey; Zhu Liyin; Stanley E Richard; Cox Dianne; Muller William J; Pollard Jeffrey W; Van Rooijen Nico; Segall Jeffrey E
The EGF/CSF-1 paracrine invasion loop can be triggered by heregulin beta1 and CXCL12.
Cancer research 2009;69(7):3221-7.
2009: Redecha Patricia; van Rooijen Nico; Torry Donald; Girardi Guillermina
Pravastatin prevents miscarriages in mice: role of tissue factor in placental and fetal injury.
Blood 2009;113(17):4101-9.
2009: Di Paolo Nelson C; van Rooijen Nico; Shayakhmetov Dmitry M
Redundant and synergistic mechanisms control the sequestration of blood-born adenovirus in the liver.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(4):675-84.
2009: Roychowdhury Sanjoy; McMullen Megan R; Pritchard Michele T; Hise Amy G; van Rooijen Nico; Medof M Edward; Stavitsky Abram B; Nagy Laura E
An early complement-dependent and TLR-4-independent phase in the pathogenesis of ethanol-induced liver injury in mice.
Hepatology (Baltimore, Md.) 2009;49(4):1326-34.
2009: Gensel John C; Nakamura Satoshi; Guan Zhen; van Rooijen Nico; Ankeny Daniel P; Popovich Phillip G
Macrophages promote axon regeneration with concurrent neurotoxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(12):3956-68.
2009: Manicone Anne M; Birkland Timothy P; Lin Michelle; Betsuyaku Tomoko; van Rooijen Nico; Lohi Jouko; Keski-Oja Jorma; Wang Ying; Skerrett Shawn J; Parks William C
Epilysin (MMP-28) restrains early macrophage recruitment in Pseudomonas aeruginosa pneumonia.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(6):3866-76.
2009: Eidsmo Liv; Allan Rhys; Caminschi Irina; van Rooijen Nico; Heath William R; Carbone Francis R
Differential migration of epidermal and dermal dendritic cells during skin infection.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(5):3165-72.
2009: Zandbergen Harmen R; Sharma Umesh C; Gupta Sudhir; Verjans Johan W H; van den Borne Susanne; Pokharel Saraswati; van Brakel Thomas; Duijvestijn Adriaan; van Rooijen Nico; Maessen Jos G; Reutelingsperger Chris; Pinto Yigal M; Narula Jagat; Hofstra Leo
Macrophage depletion in hypertensive rats accelerates development of cardiomyopathy.
Journal of cardiovascular pharmacology and therapeutics 2009;14(1):68-75.
2009: Pande Kalyan; Ueda Roanna; Machemer Todd; Sathe Manjiri; Tsai Van; Brin Elena; Delano Matthew J; Van Rooijen Nico; McClanahan Terrill K; Talmadge James E; Moldawer Lyle L; Phillips Joseph H; LaFace Drake M
Cancer-induced expansion and activation of CD11b+ Gr-1+ cells predispose mice to adenoviral-triggered anaphylactoid-type reactions.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(3):508-15.
2009: Kolaczkowska Elzbieta; Grzybek Weronika; van Rooijen Nico; Piccard Helene; Plytycz Barbara; Arnold Bernd; Opdenakker Ghislain
Neutrophil elastase activity compensates for a genetic lack of matrix metalloproteinase-9 (MMP-9) in leukocyte infiltration in a model of experimental peritonitis.
Journal of leukocyte biology 2009;85(3):374-81.
2009: Nuki Yoshitsugu; Matsumoto Melissa M; Tsang Eric; Young William L; van Rooijen Nico; Kurihara Chie; Hashimoto Tomoki
Roles of macrophages in flow-induced outward vascular remodeling.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(3):495-503.
2009: Leendertse Masja; Willems Rob J L; Giebelen Ida A J; Roelofs Joris J T H; van Rooijen Nico; Bonten Marc J M; van der Poll Tom
Peritoneal macrophages are important for the early containment of Enterococcus faecium peritonitis in mice.
Innate immunity 2009;15(1):3-12.
2009: Halin Sofia; Rudolfsson Stina Häggström; Van Rooijen Nico; Bergh Anders
Extratumoral macrophages promote tumor and vascular growth in an orthotopic rat prostate tumor model.
Neoplasia (New York, N.Y.) 2009;11(2):177-86.
2009: O'Dea Kieran P; Wilson Michael R; Dokpesi Justina O; Wakabayashi Kenji; Tatton Louise; van Rooijen Nico; Takata Masao
Mobilization and margination of bone marrow Gr-1high monocytes during subclinical endotoxemia predisposes the lungs toward acute injury.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(2):1155-66.
2009: Parker Alan L; Waddington Simon N; Buckley Suzanne M K; Custers Jerome; Havenga Menzo J E; van Rooijen Nico; Goudsmit Jaap; McVey John H; Nicklin Stuart A; Baker Andrew H
Effect of neutralizing sera on factor x-mediated adenovirus serotype 5 gene transfer.
Journal of virology 2009;83(1):479-83.
2009: Larsson Christer; Lundqvist Jenny; van Rooijen Nico; Bergström Sven
A Novel Animal Model of Borrelia recurrentis Louse-Borne Relapsing Fever Borreliosis Using Immunodeficient Mice.
PLoS neglected tropical diseases 2009;3(9):e522.
2009: Gyorki David E; Asselin-Labat Marie-Liesse; van Rooijen Nico; Lindeman Geoffrey J; Visvader Jane E
Resident macrophages influence stem cell activity in the mammary gland.
Breast cancer research : BCR 2009;11(4):R62.
2009: Traeger Tobias; Kessler Wolfram; Hilpert Anne; Mikulcak Marlene; Entleutner Markus; Koerner Pia; Westerholt Alexandra; Cziupka Katharina; van Rooijen Nico; Heidecke Claus-Dieter; Maier Stefan
Selective depletion of alveolar macrophages in polymicrobial sepsis increases lung injury, bacterial load and mortality but does not affect cytokine release.
Respiration; international review of thoracic diseases 2009;77(2):203-13.
2008: Galea Ian; Felton Leigh M; Waters Sara; van Rooijen Nico; Perry V Hugh; Newman Tracey A
Immune-to-brain signalling: the role of cerebral CD163-positive macrophages.
Neuroscience letters 2008;448(1):41-6.
2008: Färber Katrin; Synowitz Michael; Zahn Grit; Vossmeyer Dörte; Stragies Roland; van Rooijen Nico; Kettenmann Helmut
An alpha5beta1 integrin inhibitor attenuates glioma growth.
Molecular and cellular neurosciences 2008;39(4):579-85.
2008: Geiben-Lynn Ralf; Greenland John R; Frimpong-Boateng Kwesi; van Rooijen Nico; Hovav Avi-Hai; Letvin Norman L
CD4+ T lymphocytes mediate in vivo clearance of plasmid DNA vaccine antigen expression and potentiate CD8+ T-cell immune responses.
Blood 2008;112(12):4585-90.
2008: Robertson Charles M; Perrone Erin E; McConnell Kevin W; Dunne W Michael; Boody Barrett; Brahmbhatt Tejal; Diacovo M Julia; Van Rooijen Nico; Hogue Lisa A; Cannon Carolyn L; Buchman Timothy G; Hotchkiss Richard S; Coopersmith Craig M
Neutrophil depletion causes a fatal defect in murine pulmonary Staphylococcus aureus clearance.
The Journal of surgical research 2008;150(2):278-85.
2008: Bystrom Jonas; Evans Ian; Newson Justine; Stables Melanie; Toor Iqbal; van Rooijen Nico; Crawford Mark; Colville-Nash Paul; Farrow Stuart; Gilroy Derek W
Resolution-phase macrophages possess a unique inflammatory phenotype that is controlled by cAMP.
Blood 2008;112(10):4117-27.
2008: Corjon Stéphanie; Wortmann Andreas; Engler Tatjana; van Rooijen Nico; Kochanek Stefan; Kreppel Florian
Targeting of adenovirus vectors to the LRP receptor family with the high-affinity ligand RAP via combined genetic and chemical modification of the pIX capsomere.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(11):1813-24.
2008: Engel Daniel R; Maurer Juliane; Tittel André P; Weisheit Christina; Cavlar Taner; Schumak Beatrix; Limmer Andreas; van Rooijen Nico; Trautwein Christian; Tacke Frank; Kurts Christian
CCR2 mediates homeostatic and inflammatory release of Gr1(high) monocytes from the bone marrow, but is dispensable for bladder infiltration in bacterial urinary tract infection.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(8):5579-86.
2008: Okamoto Akiko; Fujio Keishi; van Rooijen Nico; Tsuno Nelson H; Takahashi Koki; Tsurui Hiromichi; Hirose Sachiko; Elkon Keith B; Yamamoto Kazuhiko
Splenic phagocytes promote responses to nucleosomes in (NZB x NZW) F1 mice.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(8):5264-71.
2008: Sivanandam Vijayshankar Ganesh; Stephen Sam Laurel; Hernandez-Alcoceba Ruben; Alzuguren Pilar; Zabala Maider; van Rooijen Nico; Qian Cheng; Berger Irina; Gross Marie-Luise; Prieto Jesus; Kochanek Stefan
Lethality in an anti-angiogenic tumor gene therapy model upon constitutive but not inducible expression of the soluble vascular endothelial growth factor receptor 1.
The journal of gene medicine 2008;10(10):1083-91.
2008: Campbell Sandra J; Zahid Imran; Losey Patrick; Law Shing; Jiang Yanyan; Bilgen Mehmet; van Rooijen Nico; Morsali Damineh; Davis Andrew E M; Anthony Daniel C
Liver Kupffer cells control the magnitude of the inflammatory response in the injured brain and spinal cord.
Neuropharmacology 2008;55(5):780-7.
2008: Fux Michaela; van Rooijen Nico; Owens Trevor
Macrophage-independent T cell infiltration to the site of injury-induced brain inflammation.
Journal of neuroimmunology 2008;203(1):64-72.
2008: Hippen Keli L; Harker-Murray Paul; Porter Stephen B; Merkel Sarah C; Londer Aryel; Taylor Dawn K; Bina Megan; Panoskaltsis-Mortari Angela; Rubinstein Pablo; Van Rooijen Nico; Golovina Tatiana N; Suhoski Megan M; Miller Jeffrey S; Wagner John E; June Carl H; Riley James L; Blazar Bruce R
Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells.
Blood 2008;112(7):2847-57.
2008: Zhou Zimei; Barrett Ronald P; McClellan Sharon A; Zhang Yunfan; Szliter Elizabeth A; van Rooijen Nico; Hazlett Linda D
Substance P delays apoptosis, enhancing keratitis after Pseudomonas aeruginosa infection.
Investigative ophthalmology & visual science 2008;49(10):4458-67.
2008: Horn Kevin P; Busch Sarah A; Hawthorne Alicia L; van Rooijen Nico; Silver Jerry
Another barrier to regeneration in the CNS: activated macrophages induce extensive retraction of dystrophic axons through direct physical interactions.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(38):9330-41.
2008: Getts Daniel R; Terry Rachael L; Getts Meghann Teague; Müller Marcus; Rana Sabita; Shrestha Bimmi; Radford Jane; Van Rooijen Nico; Campbell Iain L; King Nicholas J C
Ly6c+ "inflammatory monocytes" are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis.
The Journal of experimental medicine 2008;205(10):2319-37.
2008: van Rooijen Nico
Liposomes for targeting of antigens and drugs: immunoadjuvant activity and liposome-mediated depletion of macrophages.
Journal of drug targeting 2008;16(7):529-34.
2008: Appledorn Daniel M; Patial Sonika; McBride Aaron; Godbehere Sarah; Van Rooijen Nico; Parameswaran Narayanan; Amalfitano Andrea
Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(3):2134-44.
2008: Qiu Hongyu; Fan Yijun; Joyee Antony George; Wang Shuhe; Han Xiaobing; Bai Hong; Jiao Lei; Van Rooijen Nico; Yang Xi
Type I IFNs enhance susceptibility to Chlamydia muridarum lung infection by enhancing apoptosis of local macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(3):2092-102.
2008: Campion Sarah N; Johnson Rachel; Aleksunes Lauren M; Goedken Michael J; van Rooijen Nico; Scheffer George L; Cherrington Nathan J; Manautou José E
Hepatic Mrp4 induction following acetaminophen exposure is dependent on Kupffer cell function.
American journal of physiology. Gastrointestinal and liver physiology 2008;295(2):G294-304.
2008: Soehnlein O; Oehmcke S; Ma X; Rothfuchs A G; Frithiof R; van Rooijen N; Mörgelin M; Herwald H; Lindbom L
Neutrophil degranulation mediates severe lung damage triggered by streptococcal M1 protein.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2008;32(2):405-12.
2008: Horne Phillip H; Zimmerer Jason M; Fisher Mason G; Lunsford Keri E; Nadasdy Gyongyi; Nadasdy Tibor; van Rooijen Nico; Bumgardner Ginny L
Critical role of effector macrophages in mediating CD4-dependent alloimmune injury of transplanted liver parenchymal cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(2):1224-31.
2008: McGill Jodi; Van Rooijen Nico; Legge Kevin L
Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs.
The Journal of experimental medicine 2008;205(7):1635-46.
2008: Theurl Milan; Theurl Igor; Hochegger Kathrin; Obrist Peter; Subramaniam Nathan; van Rooijen Nico; Schuemann Klaus; Weiss Guenter
Kupffer cells modulate iron homeostasis in mice via regulation of hepcidin expression.
Journal of molecular medicine (Berlin, Germany) 2008;86(7):825-35.
2008: Zhao Aiping; Urban Joseph F; Anthony Robert M; Sun Rex; Stiltz Jennifer; van Rooijen Nico; Wynn Thomas A; Gause William C; Shea-Donohue Terez
Th2 cytokine-induced alterations in intestinal smooth muscle function depend on alternatively activated macrophages.
Gastroenterology 2008;135(1):217-225.e1.
2008: Lidbury Brett A; Rulli Nestor E; Suhrbier Andreas; Smith Paul N; McColl Shaun R; Cunningham Anthony L; Tarkowski Andrej; van Rooijen Nico; Fraser Robert J; Mahalingam Suresh
Macrophage-derived proinflammatory factors contribute to the development of arthritis and myositis after infection with an arthrogenic alphavirus.
The Journal of infectious diseases 2008;197(11):1585-93.
2008: Roth Kimberly M; Oghumu Steve; Satoskar Anjali A; Gunn John S; van Rooijen Nico; Satoskar Abhay R
Respiratory infection with Francisella novicida induces rapid dystrophic cardiac calcinosis (DCC).
FEMS immunology and medical microbiology 2008;53(1):72-8.
2008: Rival C; Theas M S; Suescun M O; Jacobo P; Guazzone V; van Rooijen N; Lustig L
Functional and phenotypic characteristics of testicular macrophages in experimental autoimmune orchitis.
The Journal of pathology 2008;215(2):108-17.
2008: Moraes Luciana Borsoi; Murakami Abel Hiroshi F; Fontes Belchor; Poggetti Renato Sergio; van Rooijen Nico; Younes Riad Nain; Heimbecker Ana Maria Cattani; Birolini Dario
Gut ischemia/reperfusion induced acute lung injury is an alveolar macrophage dependent event.
The Journal of trauma 2008;64(5):1196-200; discussion 1200-1.
2008: Kaparakis Maria; Walduck Anna K; Price Jason D; Pedersen John S; van Rooijen Nico; Pearse Martin J; Wijburg Odilia L C; Strugnell Richard A
Macrophages are mediators of gastritis in acute Helicobacter pylori infection in C57BL/6 mice.
Infection and immunity 2008;76(5):2235-9.
2008: Bakker Erik N T P; Matlung Hanke L; Bonta Peter; de Vries Carlie J; van Rooijen Nico; Vanbavel Ed
Blood flow-dependent arterial remodelling is facilitated by inflammation but directed by vascular tone.
Cardiovascular research 2008;78(2):341-8.
2008: Kim Heui Man; Lee Young-Won; Lee Ki-Ja; Kim Hyun Soo; Cho Sung Whan; van Rooijen Nico; Guan Yi; Seo Sang Heui
Alveolar macrophages are indispensable for controlling influenza viruses in lungs of pigs.
Journal of virology 2008;82(9):4265-74.
2008: Miselis Nathan R; Wu Zhijin J; Van Rooijen Nico; Kane Agnes B
Targeting tumor-associated macrophages in an orthotopic murine model of diffuse malignant mesothelioma.
Molecular cancer therapeutics 2008;7(4):788-99.
2008: Huang Y; Cen L-P; Luo J-M; Wang N; Zhang M-Z; van Rooijen N; Pang C P; Cui Q
Differential roles of phosphatidylinositol 3-kinase/akt pathway in retinal ganglion cell survival in rats with or without acute ocular hypertension.
Neuroscience 2008;153(1):214-25.
2008: Lee Pui Y; Weinstein Jason S; Nacionales Dina C; Scumpia Philip O; Li Yi; Butfiloski Edward; van Rooijen Nico; Moldawer Lyle; Satoh Minoru; Reeves Westley H
A novel type I IFN-producing cell subset in murine lupus.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(7):5101-8.
2008: Fraccarollo Daniela; Galuppo Paolo; Schraut Susanne; Kneitz Susanne; van Rooijen Nico; Ertl Georg; Bauersachs Johann
Immediate mineralocorticoid receptor blockade improves myocardial infarct healing by modulation of the inflammatory response.
Hypertension 2008;51(4):905-14.
2008: Jakubzick Claudia; Tacke Frank; Ginhoux Florent; Wagers Amy J; van Rooijen Nico; Mack Matthias; Merad Miriam; Randolph Gwendalyn J
Blood monocyte subsets differentially give rise to CD103+ and CD103- pulmonary dendritic cell populations.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(5):3019-27.
2008: Koh Andrew Y; Köhler Julia R; Coggshall Kathleen T; Van Rooijen Nico; Pier Gerald B
Mucosal damage and neutropenia are required for Candida albicans dissemination.
PLoS pathogens 2008;4(2):e35.
2008: Waddington Simon N; McVey John H; Bhella David; Parker Alan L; Barker Kristeen; Atoda Hideko; Pink Rebecca; Buckley Suzanne M K; Greig Jenny A; Denby Laura; Custers Jerome; Morita Takashi; Francischetti Ivo M B; Monteiro Robson Q; Barouch Dan H; van Rooijen Nico; Napoli Claudio; Havenga Menzo J E; Nicklin Stuart A; Baker Andrew H
Adenovirus serotype 5 hexon mediates liver gene transfer.
Cell 2008;132(3):397-409.
2008: Kelly Margaret M; McNagny Kelly; Williams David L; van Rooijen Nico; Maxwell Lori; Gwozd Carol; Mody Christopher H; Kubes Paul
The lung responds to zymosan in a unique manner independent of toll-like receptors, complement, and dectin-1.
American journal of respiratory cell and molecular biology 2008;38(2):227-38.
2008: Wakim Linda M; Waithman Jason; van Rooijen Nico; Heath William R; Carbone Francis R
Dendritic cell-induced memory T cell activation in nonlymphoid tissues.
Science (New York, N.Y.) 2008;319(5860):198-202.
2008: Bryer Scott C; Fantuzzi Giamila; Van Rooijen Nico; Koh Timothy J
Urokinase-type plasminogen activator plays essential roles in macrophage chemotaxis and skeletal muscle regeneration.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(2):1179-88.
2008: Huang Yao; Li Zhiwei; Wang Ningli; van Rooijen Nico; Cui Qi
Roles of PI3K and JAK pathways in viability of retinal ganglion cells after acute elevation of intraocular pressure in rats with different autoimmune backgrounds.
BMC neuroscience 2008;9():78.
2008: Pistea Adrian; Bakker Erik N T P; Spaan Jos A E; Hardeman Max R; van Rooijen Nico; VanBavel Ed
Small artery remodeling and erythrocyte deformability in L-NAME-induced hypertension: role of transglutaminases.
Journal of vascular research 2008;45(1):10-8.
2007: Mott Kevin; Brick David J; van Rooijen Nico; Ghiasi Homayon
Macrophages are important determinants of acute ocular HSV-1 infection in immunized mice.
Investigative ophthalmology & visual science 2007;48(12):5605-15.
2007: Couper Kevin N; Blount Daniel G; Hafalla Julius C R; van Rooijen Nico; de Souza J Brian; Riley Eleanor M
Macrophage-mediated but gamma interferon-independent innate immune responses control the primary wave of Plasmodium yoelii parasitemia.
Infection and immunity 2007;75(12):5806-18.
2007: Oflazoglu Ezogelin; Stone Ivan J; Gordon Kristine A; Grewal Iqbal S; van Rooijen Nico; Law Che-Leung; Gerber Hans-Peter
Macrophages contribute to the antitumor activity of the anti-CD30 antibody SGN-30.
Blood 2007;110(13):4370-2.
2007: Price Jason D; Simpfendorfer Kim R; Mantena Radhakrishnam R; Holden James; Heath William R; van Rooijen Nico; Strugnell Richard A; Wijburg Odilia L C
Gamma interferon-independent effects of interleukin-12 on immunity to Salmonella enterica serovar Typhimurium.
Infection and immunity 2007;75(12):5753-62.
2007: Fischer Christian; Jonckx Bart; Mazzone Massimiliano; Zacchigna Serena; Loges Sonja; Pattarini Lucia; Chorianopoulos Emmanuel; Liesenborghs Laurens; Koch Marta; De Mol Maria; Autiero Monica; Wyns Sabine; Plaisance Stephane; Moons Lieve; van Rooijen Nico; Giacca Mauro; Stassen Jean-Marie; Dewerchin Mieke; Collen Desire; Carmeliet Peter
Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels.
Cell 2007;131(3):463-75.
2007: Junt Tobias; Moseman E Ashley; Iannacone Matteo; Massberg Steffen; Lang Philipp A; Boes Marianne; Fink Katja; Henrickson Sarah E; Shayakhmetov Dmitry M; Di Paolo Nelson C; van Rooijen Nico; Mempel Thorsten R; Whelan Sean P; von Andrian Ulrich H
Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells.
Nature 2007;450(7166):110-4.
2007: Huang Yao; Cen Ling-Ping; Choy Kwong Wai; van Rooijen Nico; Wang Ningli; Pang Chi Pui; Cui Qi
JAK/STAT pathway mediates retinal ganglion cell survival after acute ocular hypertension but not under normal conditions.
Experimental eye research 2007;85(5):684-95.
2007: Borders A S; Hersh M A; Getchell M L; van Rooijen N; Cohen D A; Stromberg A J; Getchell T V
Macrophage-mediated neuroprotection and neurogenesis in the olfactory epithelium.
Physiological genomics 2007;31(3):531-43.
2007: Kolaczkowska Elzbieta; Lelito Monika; Kozakiewicz Elzbieta; van Rooijen Nico; Plytycz Barbara; Arnold Bernd
Resident peritoneal leukocytes are important sources of MMP-9 during zymosan peritonitis: superior contribution of macrophages over mast cells.
Immunology letters 2007;113(2):99-106.
2007: Huang Yao; Li Zhiwei; van Rooijen Nico; Wang Ningli; Pang Chi Pui; Cui Qi
Different responses of macrophages in retinal ganglion cell survival after acute ocular hypertension in rats with different autoimmune backgrounds.
Experimental eye research 2007;85(5):659-66.
2007: Kumar Kota Arun; Garcia Celia R S; Chandran Vandana R; Van Rooijen N; Zhou Yingyao; Winzeler Elizabeth; Nussenzweig Victor
Exposure of Plasmodium sporozoites to the intracellular concentration of potassium enhances infectivity and reduces cell passage activity.
Molecular and biochemical parasitology 2007;156(1):32-40.
2007: Flierl Michael A; Rittirsch Daniel; Nadeau Brian A; Chen Anthony J; Sarma J Vidya; Zetoune Firas S; McGuire Stephanie R; List Rachel P; Day Danielle E; Hoesel L Marco; Gao Hongwei; Van Rooijen Nico; Huber-Lang Markus S; Neubig Richard R; Ward Peter A
Phagocyte-derived catecholamines enhance acute inflammatory injury.
Nature 2007;449(7163):721-5.
2007: Fulci Giulia; Dmitrieva Nina; Gianni Davide; Fontana Elisabeth J; Pan Xiaogang; Lu Yanhui; Kaufman Claire S; Kaur Balveen; Lawler Sean E; Lee Robert J; Marsh Clay B; Brat Daniel J; van Rooijen Nico; Stemmer-Rachamimov Anat O; Hochberg Fred H; Weissleder Ralph; Martuza Robert L; Chiocca E Antonio
Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses.
Cancer research 2007;67(19):9398-406.
2007: Ohnmacht Caspar; Pullner Andrea; van Rooijen Nico; Voehringer David
Analysis of eosinophil turnover in vivo reveals their active recruitment to and prolonged survival in the peritoneal cavity.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(7):4766-74.
2007: Gonzalez Norberto C; Allen Julie; Blanco V Gustavo; Schmidt Eric J; van Rooijen Nico; Wood John G
Alveolar macrophages are necessary for the systemic inflammation of acute alveolar hypoxia.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;103(4):1386-94.
2007: DiPasquale Dana M; Cheng Ming; Billich William; Huang Sharon A; van Rooijen Nico; Hornberger Troy A; Koh Timothy J
Urokinase-type plasminogen activator and macrophages are required for skeletal muscle hypertrophy in mice.
American journal of physiology. Cell physiology 2007;293(4):C1278-85.
2007: Rivera Chantal A; Adegboyega Patrick; van Rooijen Nico; Tagalicud Arlene; Allman Monique; Wallace Matthew
Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis.
Journal of hepatology 2007;47(4):571-9.
2007: Greten Florian R; Arkan Melek C; Bollrath Julia; Hsu Li-Chung; Goode Jason; Miething Cornelius; Göktuna Serkan I; Neuenhahn Michael; Fierer Joshua; Paxian Stephan; Van Rooijen Nico; Xu Yajun; O'Cain Timothy; Jaffee Bruce B; Busch Dirk H; Duyster Justus; Schmid Roland M; Eckmann Lars; Karin Michael
NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta.
Cell 2007;130(5):918-31.
2007: Khandelwal Sanjay; van Rooijen Nico; Saxena Rajiv K
Reduced expression of CD47 during murine red blood cell (RBC) senescence and its role in RBC clearance from the circulation.
Transfusion 2007;47(9):1725-32.
2007: Cen Ling-Ping; Luo Jian-Min; Zhang Cheng-Wu; Fan You-Ming; Song Yue; So Kwok-Fai; van Rooijen Nico; Pang Chi Pui; Lam Dennis S C; Cui Qi
Chemotactic effect of ciliary neurotrophic factor on macrophages in retinal ganglion cell survival and axonal regeneration.
Investigative ophthalmology & visual science 2007;48(9):4257-66.
2007: Galea Ian; Bernardes-Silva Martine; Forse Penny A; van Rooijen Nico; Liblau Roland S; Perry V Hugh
An antigen-specific pathway for CD8 T cells across the blood-brain barrier.
The Journal of experimental medicine 2007;204(9):2023-30.
2007: Bauer Dirk; Wasmuth Susanne; Hermans Pia; Hennig Maren; Meller Karl; Meller Daniel; van Rooijen Nico; Tseng Scheffer C G; Steuhl Klaus-Peter; Heiligenhaus Arnd
On the influence of neutrophils in corneas with necrotizing HSV-1 keratitis following amniotic membrane transplantation.
Experimental eye research 2007;85(3):335-45.
2007: Luo Jian-Min; Cen Ling-Ping; Zhang Xin-Mei; Chiang Sylvia Wai-Yee; Huang Yao; Lin Dusheng; Fan You-Ming; van Rooijen Nico; Lam Dennis Shun Chiu; Pang Chi Pui; Cui Qi
PI3K/akt, JAK/STAT and MEK/ERK pathway inhibition protects retinal ganglion cells via different mechanisms after optic nerve injury.
The European journal of neuroscience 2007;26(4):828-42.
2007: Wang Hui; Madariaga Maria Lucia; Wang Shumei; Van Rooijen Nico; Oldenborg Per-Arne; Yang Yong-Guang
Lack of CD47 on nonhematopoietic cells induces split macrophage tolerance to CD47null cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(34):13744-9.
2007: Gazzaniga Silvina; Bravo Alicia I; Guglielmotti Angelo; van Rooijen Nico; Maschi Fabricio; Vecchi Annunciata; Mantovani Alberto; Mordoh José; Wainstok Rosa
Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft.
The Journal of investigative dermatology 2007;127(8):2031-41.
2007: Robinson-Smith Toni M; Isaacsohn Idit; Mercer Carol A; Zhou Mingfu; Van Rooijen Nico; Husseinzadeh Nader; McFarland-Mancini Molly M; Drew Angela F
Macrophages mediate inflammation-enhanced metastasis of ovarian tumors in mice.
Cancer research 2007;67(12):5708-16.
2007: Arnold Ludovic; Henry Adeline; Poron Françoise; Baba-Amer Yasmine; van Rooijen Nico; Plonquet Anne; Gherardi Romain K; Chazaud Bénédicte
Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis.
The Journal of experimental medicine 2007;204(5):1057-69.
2007: Reese Tiffany A; Liang Hong-Erh; Tager Andrew M; Luster Andrew D; Van Rooijen Nico; Voehringer David; Locksley Richard M
Chitin induces accumulation in tissue of innate immune cells associated with allergy.
Nature 2007;447(7140):92-6.
2007: Mocanu Joseph D; Yip Kenneth W; Alajez Nehad M; Shi Wei; Li Jian-Hua; Lunt Sarah J; Moriyama Eduardo H; Wilson Brian C; Milosevic Michael; Lo Kwok-Wai; van Rooijen Nico; Busson Pierre; Bastianutto Carlo; Liu Fei-Fei
Imaging the modulation of adenoviral kinetics and biodistribution for cancer gene therapy.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(5):921-9.
2007: Smith Philip; Mangan Niamh E; Walsh Caitriona M; Fallon Rosie E; McKenzie Andrew N J; van Rooijen Nico; Fallon Padraic G
Infection with a helminth parasite prevents experimental colitis via a macrophage-mediated mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(7):4557-66.
2007: Carbonetti Nicholas H; Artamonova Galina V; Van Rooijen Nico; Ayala Victor I
Pertussis toxin targets airway macrophages to promote Bordetella pertussis infection of the respiratory tract.
Infection and immunity 2007;75(4):1713-20.
2007: van Amerongen Machteld J; Harmsen Martin C; van Rooijen Nico; Petersen Arjen H; van Luyn Marja J A
Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice.
The American journal of pathology 2007;170(3):818-29.
2007: Gray Michael; Palispis Winnie; Popovich Phillip G; van Rooijen Nico; Gupta Ranjan
Macrophage depletion alters the blood-nerve barrier without affecting Schwann cell function after neural injury.
Journal of neuroscience research 2007;85(4):766-77.
2007: Borders Aaron S; Getchell Marilyn L; Etscheidt Jordan T; van Rooijen Nico; Cohen Donald A; Getchell Thomas V
Macrophage depletion in the murine olfactory epithelium leads to increased neuronal death and decreased neurogenesis.
The Journal of comparative neurology 2007;501(2):206-18.
2007: Lundberg Patric; Welander Paula V; Edwards Carl K; van Rooijen Nico; Cantin Edouard
Tumor necrosis factor (TNF) protects resistant C57BL/6 mice against herpes simplex virus-induced encephalitis independently of signaling via TNF receptor 1 or 2.
Journal of virology 2007;81(3):1451-60.
2007: McEarchern Julie A; Oflazoglu Ezogelin; Francisco Leigh; McDonagh Charlotte F; Gordon Kristine A; Stone Ivan; Klussman Kerry; Turcott Eileen; van Rooijen Nico; Carter Paul; Grewal Iqbal S; Wahl Alan F; Law Che-Leung
Engineered anti-CD70 antibody with multiple effector functions exhibits in vitro and in vivo antitumor activities.
Blood 2007;109(3):1185-92.
2007: Baer Kerstin; Roosevelt Michael; Clarkson Allen B; van Rooijen Nico; Schnieder Thomas; Frevert Ute
Kupffer cells are obligatory for Plasmodium yoelii sporozoite infection of the liver.
Cellular microbiology 2007;9(2):397-412.
2007: Tacke Frank; Alvarez David; Kaplan Theodore J; Jakubzick Claudia; Spanbroek Rainer; Llodra Jaime; Garin Alexandre; Liu Jianhua; Mack Matthias; van Rooijen Nico; Lira Sergio A; Habenicht Andreas J; Randolph Gwendalyn J
Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques.
The Journal of clinical investigation 2007;117(1):185-94.
2007: Blom Arjen B; van Lent Peter L; Libregts Sten; Holthuysen Astrid E; van der Kraan Peter M; van Rooijen Nico; van den Berg Wim B
Crucial role of macrophages in matrix metalloproteinase-mediated cartilage destruction during experimental osteoarthritis: involvement of matrix metalloproteinase 3.
Arthritis and rheumatism 2007;56(1):147-57.
2006: Furtado Glaucia C; Piña Beatrice; Tacke Frank; Gaupp Stefanie; van Rooijen Nico; Moran Thomas M; Randolph Gwendalyn J; Ransohoff Richard M; Chensue Stephen W; Raine Cedric S; Lira Sergio A
A novel model of demyelinating encephalomyelitis induced by monocytes and dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):6871-9.
2006: Breitbach Katrin; Klocke Sonja; Tschernig Thomas; van Rooijen Nico; Baumann Ulrich; Steinmetz Ivo
Role of inducible nitric oxide synthase and NADPH oxidase in early control of Burkholderia pseudomallei infection in mice.
Infection and immunity 2006;74(11):6300-9.
2006: Keijser S; de Keizer R J W; Prins F A; Tanke H J; van Rooijen N; Vrensen G F J M; Jager M J
A new model for limbal transplantation using E-GFP for follow-up of transplant survival.
Experimental eye research 2006;83(5):1188-95.
2006: Qualls Joseph E; Kaplan Alan M; van Rooijen Nico; Cohen Donald A
Suppression of experimental colitis by intestinal mononuclear phagocytes.
Journal of leukocyte biology 2006;80(4):802-15.
2006: Synowitz Michael; Glass Rainer; Färber Katrin; Markovic Darko; Kronenberg Golo; Herrmann Ken; Schnermann Juergen; Nolte Christiane; van Rooijen Nico; Kiwit Juergen; Kettenmann Helmut
A1 adenosine receptors in microglia control glioblastoma-host interaction.
Cancer research 2006;66(17):8550-7.
2006: Crettaz Julien; Berraondo Pedro; Mauleón Itsaso; Ochoa Laura; Shankar Vijay; Barajas Miguel; van Rooijen Nico; Kochanek Stefan; Qian Cheng; Prieto Jesús; Hernández-Alcoceba Rubén; González-Aseguinolaza Gloria
Intrahepatic injection of adenovirus reduces inflammation and increases gene transfer and therapeutic effect in mice.
Hepatology (Baltimore, Md.) 2006;44(3):623-32.
2006: Louten Jennifer; van Rooijen Nico; Biron Christine A
Type 1 IFN deficiency in the absence of normal splenic architecture during lymphocytic choriomeningitis virus infection.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(5):3266-72.
2006: Anthony Robert M; Urban Joseph F; Alem Farhang; Hamed Hossein A; Rozo Cristina T; Boucher Jean-Luc; Van Rooijen Nico; Gause William C
Memory T(H)2 cells induce alternatively activated macrophages to mediate protection against nematode parasites.
Nature medicine 2006;12(8):955-60.
2006: Wang Honglin; Peters Thorsten; Kess Daniel; Sindrilaru Anca; Oreshkova Tsvetelina; Van Rooijen Nico; Stratis Athanasios; Renkl Andreas C; Sunderkötter Cord; Wlaschek Meinhard; Haase Ingo; Scharffetter-Kochanek Karin
Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation.
The Journal of clinical investigation 2006;116(8):2105-14.
2006: Stratis Athanasios; Pasparakis Manolis; Rupec Rudolf A; Markur Doreen; Hartmann Karin; Scharffetter-Kochanek Karin; Peters Thorsten; van Rooijen Nico; Krieg Thomas; Haase Ingo
Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation.
The Journal of clinical investigation 2006;116(8):2094-104.
2006: Boonman Zita F H M; Schurmans Lucas R H M; van Rooijen Nico; Melief Cornelis J M; Toes René E M; Jager Martine J
Macrophages are vital in spontaneous intraocular tumor eradication.
Investigative ophthalmology & visual science 2006;47(7):2959-65.
2006: Bakker Erik N T P; Pistea Adrian; Spaan Jos A E; Rolf Titia; de Vries Carlie J; van Rooijen Nico; Candi Eleonara; VanBavel Ed
Flow-dependent remodeling of small arteries in mice deficient for tissue-type transglutaminase: possible compensation by macrophage-derived factor XIII.
Circulation research 2006;99(1):86-92.
2006: Kolaczkowska Elzbieta; Scislowska-Czarnecka Anna; Chadzinska Magdalena; Plytycz Barbara; van Rooijen Nico; Opdenakker Ghislain; Arnold Bernd
Enhanced early vascular permeability in gelatinase B (MMP-9)-deficient mice: putative contribution of COX-1-derived PGE2 of macrophage origin.
Journal of leukocyte biology 2006;80(1):125-32.
2006: Summan Mukesh; Warren Gordon L; Mercer Robert R; Chapman Rebecca; Hulderman Tracy; Van Rooijen Nico; Simeonova Petia P
Macrophages and skeletal muscle regeneration: a clodronate-containing liposome depletion study.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;290(6):R1488-95.
2006: Agrawal Smriti; Anderson Per; Durbeej Madeleine; van Rooijen Nico; Ivars Fredrik; Opdenakker Ghislain; Sorokin Lydia M
Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis.
The Journal of experimental medicine 2006;203(4):1007-19.
2006: Morosan Serban; Hez-Deroubaix Stéphanie; Lunel Francoise; Renia Laurent; Giannini Carlo; Van Rooijen Nico; Battaglia Serena; Blanc Catherine; Eling Wijnand; Sauerwein Robert; Hannoun Laurent; Belghiti Jacques; Brechot Christian; Kremsdorf Dina; Druilhe Pierre
Liver-stage development of Plasmodium falciparum, in a humanized mouse model.
The Journal of infectious diseases 2006;193(7):996-1004.
2006: Gehring Stephan; Dickson Elizabeth M; San Martin Maryann E; van Rooijen Nico; Papa Elaine F; Harty Mark W; Tracy Thomas F; Gregory Stephen H
Kupffer cells abrogate cholestatic liver injury in mice.
Gastroenterology 2006;130(3):810-22.
2006: Jakubzick Claudia; Tacke Frank; Llodra Jaime; van Rooijen Nico; Randolph Gwendalyn J
Modulation of dendritic cell trafficking to and from the airways.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(6):3578-84.
2006: Tacke Frank; Ginhoux Florent; Jakubzick Claudia; van Rooijen Nico; Merad Miriam; Randolph Gwendalyn J
Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery.
The Journal of experimental medicine 2006;203(3):583-97.
2006: Moreno Alicia; Ferrer Elizabeth; Arahuetes Susana; Eguiluz Cesar; Van Rooijen Nico; Benito Agustin
The course of infections and pathology in immunomodulated NOD/LtSz-SCID mice inoculated with Plasmodium falciparum laboratory lines and clinical isolates.
International journal for parasitology 2006;36(3):361-9.
2006: Le Borgne Marie; Etchart Nathalie; Goubier Anne; Lira Sergio A; Sirard Jean Claude; van Rooijen Nico; Caux Christophe; Aït-Yahia Smina; Vicari Alain; Kaiserlian Dominique; Dubois Bertrand
Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo.
Immunity 2006;24(2):191-201.
2006: Golay Josee; Cittera Elena; Di Gaetano Nicola; Manganini Massimiliano; Mosca Michela; Nebuloni Manuela; van Rooijen Nico; Vago Luca; Introna Martino
The role of complement in the therapeutic activity of rituximab in a murine B lymphoma model homing in lymph nodes.
Haematologica 2006;91(2):176-83.
2006: Frid Maria G; Brunetti Jacqueline A; Burke Danielle L; Carpenter Todd C; Davie Neil J; Reeves John T; Roedersheimer Mark T; van Rooijen Nico; Stenmark Kurt R
Hypoxia-induced pulmonary vascular remodeling requires recruitment of circulating mesenchymal precursors of a monocyte/macrophage lineage.
The American journal of pathology 2006;168(2):659-69.
2006: Haque Ashraful; Easton Anna; Smith Debbie; O'Garra Anne; Van Rooijen Nico; Lertmemongkolchai Ganjana; Titball Richard W; Bancroft Gregory J
Role of T cells in innate and adaptive immunity against murine Burkholderia pseudomallei infection.
The Journal of infectious diseases 2006;193(3):370-9.
2006: Evans Krystal J; Hansen Diana S; van Rooijen Nico; Buckingham Lynn A; Schofield Louis
Severe malarial anemia of low parasite burden in rodent models results from accelerated clearance of uninfected erythrocytes.
Blood 2006;107(3):1192-9.
2006: Cote Christopher K; Van Rooijen Nico; Welkos Susan L
Roles of macrophages and neutrophils in the early host response to Bacillus anthracis spores in a mouse model of infection.
Infection and immunity 2006;74(1):469-80.
2006: Mangan Niamh E; van Rooijen Nico; McKenzie Andrew N J; Fallon Padraic G
Helminth-modified pulmonary immune response protects mice from allergen-induced airway hyperresponsiveness.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(1):138-47.
2005: Keller Melanie; Gerbes Alexander L; Kulhanek-Heinze Stefanie; Gerwig Tobias; Grutzner Uwe; van Rooijen Nico; Vollmar Angelika M; Kiemer Alexandra K
Hepatocyte cytoskeleton during ischemia and reperfusion--influence of ANP-mediated p38 MAPK activation.
World journal of gastroenterology : WJG 2005;11(47):7418-29.
2005: Lawlor Kate E; Wong Peter K K; Campbell Ian K; van Rooijen Nico; Wicks Ian P
Acute CD4+ T lymphocyte-dependent interleukin-1-driven arthritis selectively requires interleukin-2 and interleukin-4, joint macrophages, granulocyte-macrophage colony-stimulating factor, interleukin-6, and leukemia inhibitory factor.
Arthritis and rheumatism 2005;52(12):3749-54.
2005: Tumpey Terrence M; García-Sastre Adolfo; Taubenberger Jeffery K; Palese Peter; Swayne David E; Pantin-Jackwood Mary J; Schultz-Cherry Stacey; Solórzano Alicia; Van Rooijen Nico; Katz Jacqueline M; Basler Christopher F
Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice.
Journal of virology 2005;79(23):14933-44.
2005: Höltje Markus; Hoffmann Anja; Hofmann Fred; Mucke Christian; Grosse Gisela; Van Rooijen Nico; Kettenmann Helmut; Just Ingo; Ahnert-Hilger Gudrun
Role of Rho GTPase in astrocyte morphology and migratory response during in vitro wound healing.
Journal of neurochemistry 2005;95(5):1237-48.
2005: Ezendam Janine; Kosterman Kevin; Spijkerboer Henneke; Bleumink Rob; Hassing Ine; van Rooijen Nico; Vos Joseph G; Pieters Raymond
Macrophages are involved in hexachlorobenzene-induced adverse immune effects.
Toxicology and applied pharmacology 2005;209(1):19-27.
2005: Ciavarra Richard P; Taylor Lisa; Greene Amy R; Yousefieh Nazita; Horeth Dale; van Rooijen Nico; Steel Christina; Gregory Betsy; Birkenbach Mark; Sekellick Margaret
Impact of macrophage and dendritic cell subset elimination on antiviral immunity, viral clearance and production of type 1 interferon.
Virology 2005;342(2):177-89.
2005: Oosterling Steven J; van der Bij Gerben J; Meijer Gerrit A; Tuk Cornelis W; van Garderen Evert; van Rooijen Nico; Meijer Sybren; van der Sijp Joost R M; Beelen Robert H J; van Egmond Marjolein
Macrophages direct tumour histology and clinical outcome in a colon cancer model.
The Journal of pathology 2005;207(2):147-55.
2005: Kresse Matthias; Latta Markus; Künstle Gerald; Riehle Hans-Martin; van Rooijen Nico; Hentze Hannes; Tiegs Gisa; Biburger Markus; Lucas Rudolf; Wendel Albrecht
Kupffer cell-expressed membrane-bound TNF mediates melphalan hepatotoxicity via activation of both TNF receptors.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(6):4076-83.
2005: Maruyama Kazuichi; Ii Masaaki; Cursiefen Claus; Jackson David G; Keino Hiroshi; Tomita Minoru; Van Rooijen Nico; Takenaka Hideya; D'Amore Patricia A; Stein-Streilein Joan; Losordo Douglas W; Streilein J Wayne
Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages.
The Journal of clinical investigation 2005;115(9):2363-72.
2005: Shao Xiuping; Mednick Aron; Alvarez Mauricio; van Rooijen Nico; Casadevall Arturo; Goldman David L
An innate immune system cell is a major determinant of species-related susceptibility differences to fungal pneumonia.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(5):3244-51.
2005: Newman Tracey A; Galea Ian; van Rooijen Nico; Perry V Hugh
Blood-derived dendritic cells in an acute brain injury.
Journal of neuroimmunology 2005;166(1-2):167-72.
2005: Ali Sumia; King Gwendalyn D; Curtin James F; Candolfi Marianela; Xiong Weidong; Liu Chunyan; Puntel Mariana; Cheng Queng; Prieto Jesus; Ribas Antoni; Kupiec-Weglinski Jerzy; van Rooijen Nico; Lassmann Hans; Lowenstein Pedro R; Castro Maria G
Combined immunostimulation and conditional cytotoxic gene therapy provide long-term survival in a large glioma model.
Cancer research 2005;65(16):7194-204.
2005: Machemer Todd; Engler Heidrun; Tsai Van; Lee Seoju; Cannon-Carlson Susan; Voloch Marcio; Schluep Thomas; Ravindran Sundari; Vellekamp Gary; Brin Elena; Cornell Douglas; Sutjipto Suganto; Wen Shu Fen; Horn Mark; Van Rooijen Nico; Maneval Dan; Hutchins Beth; LaFace Drake
Characterization of hemodynamic events following intravascular infusion of recombinant adenovirus reveals possible solutions for mitigating cardiovascular responses.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(2):254-63.
2005: Nierkens Stefan; Bleumink Rob; Bol Marianne; Hassing Ine; van Rooijen Nico; Pieters Raymond
The reactive D-glucopyranose moiety of streptozotocin is responsible for activation of macrophages and subsequent stimulation of CD8+ T cells.
Chemical research in toxicology 2005;18(5):872-9.
2005: Lou Dan-Qing; Lesbordes Jeanne-Claire; Nicolas Gaël; Viatte Lydie; Bennoun Myriam; Van Rooijen Nico; Kahn Axel; Renia Laurent; Vaulont Sophie
Iron- and inflammation-induced hepcidin gene expression in mice is not mediated by Kupffer cells in vivo.
Hepatology (Baltimore, Md.) 2005;41(5):1056-64.
2005: Stamatovic Svetlana M; Shakui Parvin; Keep Richard F; Moore Bethany B; Kunkel Steven L; Van Rooijen Nico; Andjelkovic Anuska V
Monocyte chemoattractant protein-1 regulation of blood-brain barrier permeability.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(5):593-606.
2005: Fukushima Atsuki; Ozaki Akemi; Ishida Waka; van Rooijen Nico; Fukata Kazuyo; Ueno Hisayuki
Suppression of macrophage infiltration into the conjunctiva by clodronate liposomes in experimental immune-mediated blepharoconjunctivitis.
Cell biology international 2005;29(4):277-86.
2005: Nemmar Abderrahim; Nemery Benoit; Hoet Peter H M; Van Rooijen Nico; Hoylaerts Marc F
Silica particles enhance peripheral thrombosis: key role of lung macrophage-neutrophil cross-talk.
American journal of respiratory and critical care medicine 2005;171(8):872-9.
2005: Nikolic Tatjana; Geutskens Sacha B; van Rooijen Nico; Drexhage Hemmo A; Leenen Pieter J M
Dendritic cells and macrophages are essential for the retention of lymphocytes in (peri)-insulitis of the nonobese diabetic mouse: a phagocyte depletion study.
Laboratory investigation; a journal of technical methods and pathology 2005;85(4):487-501.
2005: Skokowa Julia; Ali Syed R; Felda Olga; Kumar Varsha; Konrad Stephanie; Shushakova Nelli; Schmidt Reinhold E; Piekorz Roland P; Nürnberg Bernd; Spicher Karsten; Birnbaumer Lutz; Zwirner Jörg; Claassens Jill W C; Verbeek Josef S; van Rooijen Nico; Köhl Jörg; Gessner J Engelbert
Macrophages induce the inflammatory response in the pulmonary Arthus reaction through G alpha i2 activation that controls C5aR and Fc receptor cooperation.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(5):3041-50.
2005: Geier Andreas; Zollner Gernot; Dietrich Christoph G; Wagner Martin; Fickert Peter; Denk Helmut; van Rooijen Nico; Matern Siegfried; Gartung Carsten; Trauner Michael
Cytokine-independent repression of rodent Ntcp in obstructive cholestasis.
Hepatology (Baltimore, Md.) 2005;41(3):470-7.
2005: Garzón Manolo Rodrigo; Berraondo Pedro; Crettaz Julien; Ochoa Laura; Vera Maria; Lasarte Juan Jose; Vales Africa; Van Rooijen Nico; Ruiz Juan; Prieto Jesús; Zulueta Javier; González-Aseguinolaza Gloria
Induction of gp120-specific protective immune responses by genetic vaccination with linear polyethylenimine-plasmid complex.
Vaccine 2005;23(11):1384-92.
2005: Kotter Mark R; Zhao Chao; van Rooijen Nico; Franklin Robin J M
Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression.
Neurobiology of disease 2005;18(1):166-75.
2005: Galea Ian; Palin Karine; Newman Tracey A; Van Rooijen Nico; Perry V Hugh; Boche Delphine
Mannose receptor expression specifically reveals perivascular macrophages in normal, injured, and diseased mouse brain.
Glia 2005;49(3):375-84.
2005: Schmieg John; Yang Guangli; Franck Richard W; Van Rooijen Nico; Tsuji Moriya
Glycolipid presentation to natural killer T cells differs in an organ-dependent fashion.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(4):1127-32.
2005: Sturm Ekkehard; Havinga Rick; Baller Julius F W; Wolters Henk; van Rooijen Nico; Kamps Jan A A M; Verkade Henkjan J; Karpen Saul J; Kuipers Folkert
Kupffer cell depletion with liposomal clodronate prevents suppression of Ntcp expression in endotoxin-treated rats.
Journal of hepatology 2005;42(1):102-9.
2005: Tribulatti María Virginia; Mucci Juan; Van Rooijen Nico; Leguizamón María Susana; Campetella Oscar
The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents.
Infection and immunity 2005;73(1):201-7.
2005: Leemans Jaklien C; Thepen Theo; Weijer Sebastiaan; Florquin Sandrine; van Rooijen Nico; van de Winkel Jan G; van der Poll Tom
Macrophages play a dual role during pulmonary tuberculosis in mice.
The Journal of infectious diseases 2005;191(1):65-74.
2005: Moreno Sabater Alicia; Moreno Marta; Moreno Francisco Javier; Eguiluz Cesar; van Rooijen Nico; Benito Agustin
Experimental infection of immunomodulated NOD/LtSz-SCID mice as a new model for Plasmodium falciparum erythrocytic stages.
Parasitology research 2005;95(2):97-105.
2005: Bustuoabad Oscar D; Ruggiero Raúl A; di Gianni Pedro; Lombardi M Gabriela; Belli Carolina; Camerano Gabriela V; Dran Graciela; Schere-Levy Carolina; Costa Héctor; Isturiz Martin A; Narvaitz Marina; van Rooijen Nico; Bustuoabad Victoria de los A; Meiss Roberto P
Tumor transition zone: a putative new morphological and functional hallmark of tumor aggressiveness.
Oncology research 2005;15(3):169-82.
2004: Qu Chunfeng; Edwards Emmerson W; Tacke Frank; Angeli Véronique; Llodrá Jaime; Sanchez-Schmitz Guzman; Garin Alexandre; Haque Nasreen S; Peters Wendy; van Rooijen Nico; Sanchez-Torres Carmen; Bromberg Jonathan; Charo Israel F; Jung Steffen; Lira Sergio A; Randolph Gwendalyn J
Role of CCR8 and other chemokine pathways in the migration of monocyte-derived dendritic cells to lymph nodes.
The Journal of experimental medicine 2004;200(10):1231-41.
2004: Mangan Niamh E; Fallon Rosemary E; Smith Philip; van Rooijen Nico; McKenzie Andrew N; Fallon Padraic G
Helminth infection protects mice from anaphylaxis via IL-10-producing B cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(10):6346-56.
2004: Cote Christopher K; Rea Kelly M; Norris Sarah L; van Rooijen Nico; Welkos Susan L
The use of a model of in vivo macrophage depletion to study the role of macrophages during infection with Bacillus anthracis spores.
Microbial pathogenesis 2004;37(4):169-75.
2004: Jiang Zhilong; Schiedner Gudrun; van Rooijen Nico; Liu Chau-Ching; Kochanek Stefan; Clemens Paula R
Sustained muscle expression of dystrophin from a high-capacity adenoviral vector with systemic gene transfer of T cell costimulatory blockade.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(4):688-96.
2004: Godau Jeanne; Heller Tanja; Hawlisch Heiko; Trappe Matthew; Howells Elaine; Best Jennifer; Zwirner Jörg; Verbeek J Sjef; Hogarth P Mark; Gerard Craig; Van Rooijen Nico; Klos Andreas; Gessner J Engelbert; Köhl Jörg
C5a initiates the inflammatory cascade in immune complex peritonitis.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(5):3437-45.
2004: Blom Arjen B; van Lent Peter L E M; Holthuysen Astrid E M; van der Kraan Peter M; Roth Johannes; van Rooijen Nico; van den Berg Wim B
Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2004;12(8):627-35.
2004: Sammels Leanne M; Bosio Erika; Fragall Clayton T; Grounds Miranda D; van Rooijen Nico; Beilharz Manfred W
Innate inflammatory cells are not responsible for early death of donor myoblasts after myoblast transfer therapy.
Transplantation 2004;77(12):1790-7.
2004: Slegers Tanja P A M; Broersma Lidy; van Rooijen Nico; Hooymans Johanna M M; van Rij Gabriel; van der Gaag Ruth
Macrophages play a role in the early phase of corneal allograft rejection in rats.
Transplantation 2004;77(11):1641-6.
2004: Gao Hongwei; Guo Ren-Feng; Speyer Cecilia L; Reuben Jayne; Neff Thomas A; Hoesel L Marco; Riedemann Niels C; McClintock Shannon D; Sarma J Vidya; Van Rooijen Nico; Zetoune Firas S; Ward Peter A
Stat3 activation in acute lung injury.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(12):7703-12.
2004: Lee Ann M; Fryer Allison D; van Rooijen Nico; Jacoby David B
Role of macrophages in virus-induced airway hyperresponsiveness and neuronal M2 muscarinic receptor dysfunction.
American journal of physiology. Lung cellular and molecular physiology 2004;286(6):L1255-9.
2004: Hughes Edward H; Schlichtenbrede Frank C; Murphy Conor C; Broderick Cathryn; van Rooijen Nico; Ali Robin R; Dick Andrew D
Minocycline delays photoreceptor death in the rds mouse through a microglia-independent mechanism.
Experimental eye research 2004;78(6):1077-84.
2004: Wolff Randal A; Tomas Jeffrey J; Hullett Debra A; Stark V Emily; van Rooijen Nico; Hoch John R
Macrophage depletion reduces monocyte chemotactic protein-1 and transforming growth factor-beta1 in healing rat vein grafts.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter 2004;39(4):878-88.
2004: Drevets Douglas A; Dillon Marilyn J; Schawang Jennifer S; Van Rooijen Nico; Ehrchen Jan; Sunderkötter Cord; Leenen Pieter J M
The Ly-6Chigh monocyte subpopulation transports Listeria monocytogenes into the brain during systemic infection of mice.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(7):4418-24.
2004: Sunderkötter Cord; Nikolic Tatjana; Dillon Marilyn J; Van Rooijen Nico; Stehling Martin; Drevets Douglas A; Leenen Pieter J M
Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(7):4410-7.
2004: Silva Grace C; Nagib Patrícia R A; Chiari Egler; van Rooijen Nico; Machado Conceição R S; Camargos Elizabeth R S
Peripheral macrophage depletion reduces central nervous system parasitism and damage in Trypanosoma cruzi-infected suckling rats.
Journal of neuroimmunology 2004;149(1-2):50-8.
2004: Jasinski Marek; Pantazopoulos Panagiotis; Rother Russell P; van Rooijen Nico; Song Wen-Chao; Molina Hector; Bessler Monica
A novel mechanism of complement-independent clearance of red cells deficient in glycosyl phosphatidylinositol-linked proteins.
Blood 2004;103(7):2827-34.
2004: Mühlen Katrin A; Schümann Jens; Wittke Frederick; Stenger Steffen; Van Rooijen Nico; Van Kaer Luc; Tiegs Gisa
NK cells, but not NKT cells, are involved in Pseudomonas aeruginosa exotoxin A-induced hepatotoxicity in mice.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(5):3034-41.
2004: Marín-Teva José Luis; Dusart Isabelle; Colin Catherine; Gervais Annie; van Rooijen Nico; Mallat Michel
Microglia promote the death of developing Purkinje cells.
Neuron 2004;41(4):535-47.
2004: van Lent P L E M; Blom A B; van der Kraan P; Holthuysen A E M; Vitters E; van Rooijen N; Smeets R L; Nabbe K C A M; van den Berg W B
Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation.
Arthritis and rheumatism 2004;50(1):103-11.
2004: Chadzinska Magdalena; Kolaczkowska Elzbieta; Scislowska-Czarnecka Anna; Van Rooijen Nico; Plytycz Barbara
Effects of macrophage depletion on peritoneal inflammation in swiss mice, edible frogs and goldfish.
Folia biologica 2004;52(3-4):225-31.
2004: Landoni V I; Vermeulen M; Van Rooijen N; Gómez S; Palermo M; Isturiz M A; Alves-Rosa F
Macrophage derived signalling regulates negatively the megakaryocyte compartment.
Cellular and molecular biology (Noisy-le-Grand, France) 2004;50 Online Pub():OL667-75.
2003: Saeij Jeroen P J; Groeneveld Adrie; Van Rooijen Nico; Haenen Olga L M; Wiegertjes Geert F
Minor effect of depletion of resident macrophages from peritoneal cavity on resistance of common carp Cyprinus carpio to blood flagellates.
Diseases of aquatic organisms 2003;57(1-2):67-75.
2003: Schiedner Gudrun; Bloch Wilhelm; Hertel Sabine; Johnston Marion; Molojavyi Andrei; Dries Volker; Varga Georg; Van Rooijen Nico; Kochanek Stefan
A hemodynamic response to intravenous adenovirus vector particles is caused by systemic Kupffer cell-mediated activation of endothelial cells.
Human gene therapy 2003;14(17):1631-41.
2003: Jose Matthew D; Ikezumi Yohei; van Rooijen Nico; Atkins Robert C; Chadban Steven J
Macrophages act as effectors of tissue damage in acute renal allograft rejection.
Transplantation 2003;76(7):1015-22.
2003: Emoto Masashi; Miyamoto Mamiko; Emoto Yoshiko; Yoshizawa Izumi; Brinkmann Volker; van Rooijen Nico; Kaufmann Stefan H E
Highly biased type 1 immune responses in mice deficient in LFA-1 in Listeria monocytogenes infection are caused by elevated IL-12 production by granulocytes.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(8):3970-6.
2003: Sheikh Nadeem A; Attard George S; van Rooijen Nico; Rajananthanan Palasingam; Hariharan Kandasamy; Yang Ya-Wun; Morrow W John W
Differential requirements for CTL generation by novel immunostimulants: APC tropism, use of the TAP-independent processing pathway, and dependency on CD80/CD86 costimulation.
Vaccine 2003;21(25-26):3775-88.
2003: Nolte Martijn A; Beliën Jeroen A M; Schadee-Eestermans Inge; Jansen Wendy; Unger Wendy W J; van Rooijen Nico; Kraal Georg; Mebius Reina E
A conduit system distributes chemokines and small blood-borne molecules through the splenic white pulp.
The Journal of experimental medicine 2003;198(3):505-12.
2003: Popovich Phillip G; van Rooijen Nico; Hickey William F; Preidis Geoff; McGaughy Violeta
Hematogenous macrophages express CD8 and distribute to regions of lesion cavitation after spinal cord injury.
Experimental neurology 2003;182(2):275-87.
2003: Sakurai Eiji; Anand Akshay; Ambati Balamurali K; van Rooijen Nico; Ambati Jayakrishna
Macrophage depletion inhibits experimental choroidal neovascularization.
Investigative ophthalmology & visual science 2003;44(8):3578-85.
2003: Naidu Babu V; Krishnadasan Baiya; Farivar Alexander S; Woolley Steven M; Thomas Robert; Van Rooijen Nico; Verrier Edward D; Mulligan Michael S
Early activation of the alveolar macrophage is critical to the development of lung ischemia-reperfusion injury.
The Journal of thoracic and cardiovascular surgery 2003;126(1):200-7.
2003: Emoto Masashi; Emoto Yoshiko; Brinkmann Volker; Miyamoto Mamiko; Yoshizawa Izumi; Stäber Manuela; van Rooijen Nico; Hamann Alf; Kaufmann Stefan H E
Increased resistance of LFA-1-deficient mice to lipopolysaccharide-induced shock/liver injury in the presence of TNF-alpha and IL-12 is mediated by IL-10: a novel role for LFA-1 in the regulation of the proinflammatory and anti-inflammatory cytokine balance.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):584-93.
2003: Belnoue Elodie; Costa Fabio T M; Vigário Ana M; Voza Tatiana; Gonnet Françoise; Landau Irène; Van Rooijen Nico; Mack Matthias; Kuziel William A; Rénia Laurent
Chemokine receptor CCR2 is not essential for the development of experimental cerebral malaria.
Infection and immunity 2003;71(6):3648-51.
2003: McClellan Sharon A; Huang Xi; Barrett Ronald P; van Rooijen Nico; Hazlett Linda D
Macrophages restrict Pseudomonas aeruginosa growth, regulate polymorphonuclear neutrophil influx, and balance pro- and anti-inflammatory cytokines in BALB/c mice.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(10):5219-27.
2003: Slegers Tanja P A M; van der Veen Gerard; Hermans L Joep A; Broersma Lidy; van Rooijen Nico; Völker-Dieben Hendrika J; van Rij Gabriel; van der Gaag Ruth
Adhesion molecule expression in local-macrophage-depleted rats bearing orthotopic corneal allografts.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2003;241(5):432-8.
2003: Omer Abdulkadir; Keegan Mitchell; Czismadia Eva; De Vos Paul; Van Rooijen Nico; Bonner-Weir Susan; Weir Gordon C
Macrophage depletion improves survival of porcine neonatal pancreatic cell clusters contained in alginate macrocapsules transplanted into rats.
Xenotransplantation 2003;10(3):240-51.
2003: Wu Guosheng; Korsgren Olle; Sun Shibo; Van Rooijen Nico; Tibell Annika
Effect of plasma exchange in combination with deoxyspergualin on the survival of guinea-pig hearts in macrophage-depleted C6-deficient rats.
Xenotransplantation 2003;10(3):214-22.
2003: Rivas Christelle; Djeraba Aouatef; Musset Eugène; van Rooijen Nico; Baaten Bas; Quéré Pascale
Intravenous treatment with liposome-encapsulated dichloromethylene bisphosphonate (Cl2MBP) suppresses nitric oxide production and reduces genetic resistance to Marek's disease.
Avian pathology : journal of the W.V.P.A 2003;32(2):139-49.
2003: Alves-Rosa Fernanda; Vermeulen Mónica; Cabrera Juana; Stanganelli Carmen; Capozzo Alejandra; Narbaitz Marina; van Rooijen Nico; Palermo Marina; Isturiz Martín A
Macrophage depletion following liposomal-encapsulated clodronate (LIP-CLOD) injection enhances megakaryocytopoietic and thrombopoietic activities in mice.
British journal of haematology 2003;121(1):130-8.
2003: Masztalerz Agnieszka; Van Rooijen Nico; Den Otter Willem; Everse Linda A
Mechanisms of macrophage cytotoxicity in IL-2 and IL-12 mediated tumour regression.
Cancer immunology, immunotherapy : CII 2003;52(4):235-42.
2003: Dickson Brendan C; Yang Hua; Savelkoul Huub F J; Rowden Geoff; van Rooijen Nico; Wright James R
Islet transplantation in the discordant tilapia-to-mouse model: a novel application of alginate microencapsulation in the study of xenograft rejection.
Transplantation 2003;75(5):599-606.
2003: Selzner Nazia; Selzner Markus; Odermatt Bernhard; Tian Yinghua; Van Rooijen Nico; Clavien Pierre-Alain
ICAM-1 triggers liver regeneration through leukocyte recruitment and Kupffer cell-dependent release of TNF-alpha/IL-6 in mice.
Gastroenterology 2003;124(3):692-700.
2003: Yi Shounan; Hawthorne Wayne J; Lehnert Anne M; Ha Hong; Wong Jeferey Kwok Wah; van Rooijen Nico; Davey Kelly; Patel Anita T; Walters Stacey N; Chandra Abhilash; O'Connell Philip J
T cell-activated macrophages are capable of both recognition and rejection of pancreatic islet xenografts.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(5):2750-8.
2003: Chuah Marinee K L; Schiedner Gudrun; Thorrez Lieven; Brown Brian; Johnston Marion; Gillijns Veerle; Hertel Sabine; Van Rooijen Nico; Lillicrap David; Collen Désiré; VandenDriessche Thierry; Kochanek Stefan
Therapeutic factor VIII levels and negligible toxicity in mouse and dog models of hemophilia A following gene therapy with high-capacity adenoviral vectors.
Blood 2003;101(5):1734-43.
2003: Slegers Tanja P A M; van der Gaag Ruth; van Rooijen Nico; van Rij Gabriel; Streilein J Wayne
Effect of local macrophage depletion on cellular immunity and tolerance evoked by corneal allografts.
Current eye research 2003;26(2):73-9.
2003: Schiedner Gudrun; Hertel Sabine; Johnston Marion; Dries Volker; van Rooijen Nico; Kochanek Stefan
Selective depletion or blockade of Kupffer cells leads to enhanced and prolonged hepatic transgene expression using high-capacity adenoviral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;7(1):35-43.
2003: Knapp Sylvia; Leemans Jaklien C; Florquin Sandrine; Branger Judith; Maris Nico A; Pater Jennie; van Rooijen Nico; van der Poll Tom
Alveolar macrophages have a protective antiinflammatory role during murine pneumococcal pneumonia.
American journal of respiratory and critical care medicine 2003;167(2):171-9.
2003: Jordan Michael B; van Rooijen Nico; Izui Shozo; Kappler John; Marrack Philippa
Liposomal clodronate as a novel agent for treating autoimmune hemolytic anemia in a mouse model.
Blood 2003;101(2):594-601.
2003: van Rooijen Nico; van Kesteren-Hendrikx Esther
"In vivo" depletion of macrophages by liposome-mediated "suicide".
Methods in enzymology 2003;373():3-16.
2002: Belnoue Elodie; Kayibanda Michèle; Vigario Ana M; Deschemin Jean-Christophe; van Rooijen Nico; Viguier Mireille; Snounou Georges; Rénia Laurent
On the pathogenic role of brain-sequestered alphabeta CD8+ T cells in experimental cerebral malaria.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(11):6369-75.
2002: Sedger Lisa M; Hou Sam; Osvath Sarah R; Glaccum Moira B; Peschon Jacques J; van Rooijen Nico; Hyland Lisa
Bone marrow B cell apoptosis during in vivo influenza virus infection requires TNF-alpha and lymphotoxin-alpha.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(11):6193-201.
2002: Knudsen Eirunn; Iversen Per Ole; Van Rooijen Nico; Benestad Haakon Breien
Macrophage-dependent regulation of neutrophil mobilization and chemotaxis during development of sterile peritonitis in the rat.
European journal of haematology 2002;69(5-6):284-96.
2002: Haeberle Helene A; Takizawa Ryuta; Casola Antonella; Brasier Allan R; Dieterich Hans-Juergen; Van Rooijen Nico; Gatalica Zoran; Garofalo Roberto P
Respiratory syncytial virus-induced activation of nuclear factor-kappaB in the lung involves alveolar macrophages and toll-like receptor 4-dependent pathways.
The Journal of infectious diseases 2002;186(9):1199-206.
2002: Bauer Dirk; Schmitz Andreas; Van Rooijen Nico; Steuhl Klaus-Peter; Heiligenhaus Arnd
Conjunctival macrophage-mediated influence of the local and systemic immune response after corneal herpes simplex virus-1 infection.
Immunology 2002;107(1):118-28.
2002: Wijburg Odilia L C; Van Rooijen Nico; Strugnell Richard A
Induction of CD8+ T lymphocytes by Salmonella typhimurium is independent of Salmonella pathogenicity island 1-mediated host cell death.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(6):3275-83.
2002: Marshall John; McEachern Kerry Anne; Kyros Julie A Cavanagh; Nietupski Jennifer B; Budzinski Tracey; Ziegler Robin J; Yew Nelson S; Sullivan Jennifer; Scaria Abraham; van Rooijen Nico; Barranger John A; Cheng Seng H
Demonstration of feasibility of in vivo gene therapy for Gaucher disease using a chemically induced mouse model.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(2):179-89.
2002: Guo Ren-Feng; Lentsch Alex B; Sarma J Vidya; Sun Lei; Riedemann Niels C; McClintock Shannon D; McGuire Stephanie R; Van Rooijen Nico; Ward Peter A
Activator protein-1 activation in acute lung injury.
The American journal of pathology 2002;161(1):275-82.
2002: Ziegler Robin J; Li Chester; Cherry Maribeth; Zhu Yunxiang; Hempel Donna; van Rooijen Nico; Ioannou Yiannis A; Desnick Robert J; Goldberg Mark A; Yew Nelson S; Cheng Seng H
Correction of the nonlinear dose response improves the viability of adenoviral vectors for gene therapy of Fabry disease.
Human gene therapy 2002;13(8):935-45.
2002: Djeraba Aouatef; Musset Eugène; van Rooijen Nico; Quéré Pascale
Resistance and susceptibility to Marek's disease: nitric oxide synthase/arginase activity balance.
Veterinary microbiology 2002;86(3):229-44.
2002: Kolaczkowska Elzbieta; Shahzidi Susan; Seljelid Rolf; van Rooijen Nico; Plytycz Barbara
Early vascular permeability in murine experimental peritonitis is co-mediated by resident peritoneal macrophages and mast cells: crucial involvement of macrophage-derived cysteinyl-leukotrienes.
Inflammation 2002;26(2):61-71.
2002: van Rooijen Nico; van Kesteren-Hendrikx Esther
Clodronate liposomes: perspectives in research and therapeutics.
Journal of liposome research 2002;12(1-2):81-94.
2002: Alves-Rosa Fernanda; Stanganelli Carmen; Cabrera Juana; Cymberknop Dora; Rubel Carolina; Vanzulli Silvia; van Rooijen Nico; Palermo Marina; Isturiz Martín A
Rapid recovery of platelet count following administration of liposome-encapsulated clodronate in a mouse model of immune thrombocytopenia.
British journal of haematology 2002;116(2):357-66.
2002: Kielian Tammy; van Rooijen Nico; Hickey William F
MCP-1 expression in CNS-1 astrocytoma cells: implications for macrophage infiltration into tumors in vivo.
Journal of neuro-oncology 2002;56(1):1-12.
2002: Polfliet Machteld M J; van de Veerdonk F; Döpp Ed A; van Kesteren-Hendrikx Esther M L; van Rooijen Nico; Dijkstra Christine D; van den Berg Timo K
The role of perivascular and meningeal macrophages in experimental allergic encephalomyelitis.
Journal of neuroimmunology 2002;122(1-2):1-8.
2002: Gregory Stephen H; Cousens Leslie P; van Rooijen Nico; Döpp Ed A; Carlos Timothy M; Wing Edward J
Complementary adhesion molecules promote neutrophil-Kupffer cell interaction and the elimination of bacteria taken up by the liver.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):308-15.
2001: Wu G; Korsgren O; van Rooijen N; Tibell A
Suppression of T cells results in long-term survival of mouse heart xenografts in C6-deficient rats.
Xenotransplantation 2001;8(4):303-9.
2001: Polfliet M M; Zwijnenburg P J; van Furth A M; van der Poll T; Döpp E A; Renardel de Lavalette C; van Kesteren-Hendrikx E M; van Rooijen N; Dijkstra C D; van den Berg T K
Meningeal and perivascular macrophages of the central nervous system play a protective role during bacterial meningitis.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(8):4644-50.
2001: Kotter M R; Setzu A; Sim F J; Van Rooijen N; Franklin R J
Macrophage depletion impairs oligodendrocyte remyelination following lysolecithin-induced demyelination.
Glia 2001;35(3):204-12.
2001: Laverman P; Carstens M G; Boerman O C; Dams E T; Oyen W J; van Rooijen N; Corstens F H; Storm G
Factors affecting the accelerated blood clearance of polyethylene glycol-liposomes upon repeated injection.
The Journal of pharmacology and experimental therapeutics 2001;298(2):607-12.
2001: Polfliet M M; Goede P H; van Kesteren-Hendrikx E M; van Rooijen N; Dijkstra C D; van den Berg T K
A method for the selective depletion of perivascular and meningeal macrophages in the central nervous system.
Journal of neuroimmunology 2001;116(2):188-95.
2001: Moreno A; Badell E; Van Rooijen N; Druilhe P
Human malaria in immunocompromised mice: new in vivo model for chemotherapy studies.
Antimicrobial agents and chemotherapy 2001;45(6):1847-53.
2001: Salez L; Balloy V; van Rooijen N; Lebastard M; Touqui L; McCormack F X; Chignard M
Surfactant protein A suppresses lipopolysaccharide-induced IL-10 production by murine macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(10):6376-82.
2001: Guillot C; Coathalem H; Chetritt J; David A; Lowenstein P; Gilbert E; Tesson L; van Rooijen N; Cuturi M C; Soulillou J P; Anegon I
Lethal hepatitis after gene transfer of IL-4 in the liver is independent of immune responses and dependent on apoptosis of hepatocytes: a rodent model of IL-4-induced hepatitis.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(8):5225-35.
2001: Leemans J C; Juffermans N P; Florquin S; van Rooijen N; Vervoordeldonk M J; Verbon A; van Deventer S J; van der Poll T
Depletion of alveolar macrophages exerts protective effects in pulmonary tuberculosis in mice.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(7):4604-11.
2001: Bauer D; Mrzyk S; Van Rooijen N; Steuhl K P; Heiligenhaus A
Incidence and severity of herpetic stromal keratitis: impaired by the depletion of lymph node macrophages.
Experimental eye research 2001;72(3):261-9.
2001: Lehner M D; Ittner J; Bundschuh D S; van Rooijen N; Wendel A; Hartung T
Improved innate immunity of endotoxin-tolerant mice increases resistance to Salmonella enterica serovar typhimurium infection despite attenuated cytokine response.
Infection and immunity 2001;69(1):463-71.
2000: Ciavarra R P; Greene A R; Horeth D R; Buhrer K; van Rooijen N; Tedeschi B
Antigen processing of vesicular stomatitis virus in situ. Interdigitating dendritic cells present viral antigens independent of marginal dendritic cells but fail to prime CD4(+) and CD8(+) T cells.
Immunology 2000;101(4):512-20.
2000: Badell E; Oeuvray C; Moreno A; Soe S; van Rooijen N; Bouzidi A; Druilhe P
Human malaria in immunocompromised mice: an in vivo model to study defense mechanisms against Plasmodium falciparum.
The Journal of experimental medicine 2000;192(11):1653-60.
2000: Schümann J; Wolf D; Pahl A; Brune K; Papadopoulos T; van Rooijen N; Tiegs G
Importance of Kupffer cells for T-cell-dependent liver injury in mice.
The American journal of pathology 2000;157(5):1671-83.
2000: Emoto M; Miyamoto M; Namba K; Schmits R; Van Rooijen N; Kita E; Kaufmann S H
Participation of leukocyte function-associated antigen-1 and NK cells in the homing of thymic CD8+NKT cells to the liver.
European journal of immunology 2000;30(10):3049-56.
2000: Alves-Rosa F; Stanganelli C; Cabrera J; van Rooijen N; Palermo M S; Isturiz M A
Treatment with liposome-encapsulated clodronate as a new strategic approach in the management of immune thrombocytopenic purpura in a mouse model.
Blood 2000;96(8):2834-40.
2000: Wu G; Korsgren O; Zhang J; Song Z; van Rooijen N; Tibell A
Pig islet xenograft rejection is markedly delayed in macrophage-depleted mice: a study in streptozotocin diabetic animals.
Xenotransplantation 2000;7(3):214-20.
2000: Wu G S; Korsgren O; Zhang J G; Song Z S; Van Rooijen N; Tibell A
Role of macrophages and natural killer cells in the rejection of pig islet xenografts in mice.
Transplantation proceedings 2000;32(5):1069.
2000: Miyamoto M; Emoto M; Brinkmann V; van Rooijen N; Schmits R; Kita E; Kaufmann S H
Cutting edge: contribution of NK cells to the homing of thymic CD4+NKT cells to the liver.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(4):1729-32.
2000: Slegers T P; Torres P F; Broersma L; van Rooijen N; van Rij G; van der Gaag R
Effect of macrophage depletion on immune effector mechanisms during corneal allograft rejection in rats.
Investigative ophthalmology & visual science 2000;41(8):2239-47.
2000: Laverman P; Brouwers A H; Dams E T; Oyen W J; Storm G; van Rooijen N; Corstens F H; Boerman O C
Preclinical and clinical evidence for disappearance of long-circulating characteristics of polyethylene glycol liposomes at low lipid dose.
The Journal of pharmacology and experimental therapeutics 2000;293(3):996-1001.
2000: Slegers T P; van Rooijen N; van Rij G; van der Gaag R
Delayed graft rejection in pre-vascularised corneas after subconjunctival injection of clodronate liposomes.
Current eye research 2000;20(4):322-4.
2000: Wijburg O L; Simmons C P; van Rooijen N; Strugnell R A
Dual role for macrophages in vivo in pathogenesis and control of murine Salmonella enterica var. Typhimurium infections.
European journal of immunology 2000;30(3):944-53.
2000: Meijer C; Wiezer M J; Diehl A M; Schouten H J; Schouten H J; Meijer S; van Rooijen N; van Lambalgen A A; Dijkstra C D; van Leeuwen P A
Kupffer cell depletion by CI2MDP-liposomes alters hepatic cytokine expression and delays liver regeneration after partial hepatectomy.
Liver 2000;20(1):66-77.
2000: Westerhuis R; van Straaten S C; van Dixhoorn M G; van Rooijen N; Verhagen N A; Dijkstra C D; de Heer E; Daha M R
Distinctive roles of neutrophils and monocytes in anti-thy-1 nephritis.
The American journal of pathology 2000;156(1):303-10.
2000: Bauer D; Mrzyk S; van Rooijen N; Steuhl K P; Heiligenhaus A
Macrophage-depletion influences the course of murine HSV-1 keratitis.
Current eye research 2000;20(1):45-53.
1999: Torres P F; Slegers T P; Peek R; van Rooijen N; van der Gaag R; Kijlstra A; de Vos A F
Changes in cytokine mRNA levels in experimental corneal allografts after local clodronate-liposome treatment.
Investigative ophthalmology & visual science 1999;40(13):3194-201.
1999: Wu G; Korsgren O; van Rooijen N; Wennberg L; Tibell A
The effect of macrophage depletion on delayed xenograft rejection: studies in the guinea pig-to-C6-deficient rat heart transplantation model.
Xenotransplantation 1999;6(4):262-70.
1999: Hoch J R; Stark V K; van Rooijen N; Kim J L; Nutt M P; Warner T F
Macrophage depletion alters vein graft intimal hyperplasia.
Surgery 1999;126(2):428-37.
1999: Popovich P G; Guan Z; Wei P; Huitinga I; van Rooijen N; Stokes B T
Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury.
Experimental neurology 1999;158(2):351-65.
1999: Kopydlowski K M; Salkowski C A; Cody M J; van Rooijen N; Major J; Hamilton T A; Vogel S N
Regulation of macrophage chemokine expression by lipopolysaccharide in vitro and in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(3):1537-44.
1999: Hanson L K; Slater J S; Karabekian Z; Virgin H W; Biron C A; Ruzek M C; van Rooijen N; Ciavarra R P; Stenberg R M; Campbell A E
Replication of murine cytomegalovirus in differentiated macrophages as a determinant of viral pathogenesis.
Journal of virology 1999;73(7):5970-80.
1999: Jiang Q; Detolla L; Singh I S; Gatdula L; Fitzgerald B; van Rooijen N; Cross A S; Hasday J D
Exposure to febrile temperature upregulates expression of pyrogenic cytokines in endotoxin-challenged mice.
The American journal of physiology 1999;276(6 Pt 2):R1653-60.
1999: Palermo M S; Alves Rosa M F; Van Rooijen N; Isturiz M A
Depletion of liver and splenic macrophages reduces the lethality of Shiga toxin-2 in a mouse model.
Clinical and experimental immunology 1999;116(3):462-7.
1999: Jiang Q; DeTolla L; van Rooijen N; Singh I S; Fitzgerald B; Lipsky M M; Kane A S; Cross A S; Hasday J D
Febrile-range temperature modifies early systemic tumor necrosis factor alpha expression in mice challenged with bacterial endotoxin.
Infection and immunity 1999;67(4):1539-46.
1998: Van der Veen G; Broersma L; Van Rooijen N; Van Rij G; Van der Gaag R
Cytotoxic T lymphocytes and antibodies after orthotropic penetrating keratoplasty in rats treated with dichloromethylene diphosphonate encapsulated liposomes.
Current eye research 1998;17(10):1018-26.
1998: Bakker J; Sanders A; Van Rooijen N
Effects of liposome-encapsulated drugs on macrophages: comparative activity of the diamidine 4',6-diamidino-2-phenylindole and the phenanthridinium salts ethidium bromide and propidium iodide.
Biochimica et biophysica acta 1998;1373(1):93-100.
1998: Gregory S H; Wing E J; Danowski K L; van Rooijen N; Dyer K F; Tweardy D J
IL-6 produced by Kupffer cells induces STAT protein activation in hepatocytes early during the course of systemic listerial infections.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(12):6056-61.
1998: Oussoren C; Velinova M; Scherphof G; van der Want J J; van Rooijen N; Storm G
Lymphatic uptake and biodistribution of liposomes after subcutaneous injection . IV. Fate of liposomes in regional lymph nodes.
Biochimica et biophysica acta 1998;1370(2):259-72.
1998: Wijburg O L; van den Dobbelsteen G P; Vadolas J; Sanders A; Strugnell R A; van Rooijen N
The role of macrophages in the induction and regulation of immunity elicited by exogenous antigens.
European journal of immunology 1998;28(2):479-87.
1997: van Rooijen N; Sanders A
Elimination, blocking, and activation of macrophages: three of a kind?
Journal of leukocyte biology 1997;62(6):702-9.
1997: Wijburg O L; DiNatale S; Vadolas J; van Rooijen N; Strugnell R A
Alveolar macrophages regulate the induction of primary cytotoxic T-lymphocyte responses during influenza virus infection.
Journal of virology 1997;71(12):9450-7.
1997: Wijburg O L; Heemskerk M H; Boog C J; Van Rooijen N
Role of spleen macrophages in innate and acquired immune responses against mouse hepatitis virus strain A59.
Immunology 1997;92(2):252-8.
1997: van Rooijen N; Bakker J; Sanders A
Transient suppression of macrophage functions by liposome-encapsulated drugs.
Trends in biotechnology 1997;15(5):178-85.
1997: Rossi C P; Delcroix M; Huitinga I; McAllister A; van Rooijen N; Claassen E; Brahic M
Role of macrophages during Theiler's virus infection.
Journal of virology 1997;71(4):3336-40.
1997: Reinders M E; van Wagensveld B A; van Gulik T M; Corssmit N P; Frederiks W M; Chamuleau R A; van Rooijen N; Obertop H
No attenuation of ischemic and reperfusion injury in Kupffer cell-depleted, cold-preserved rat livers.
Transplantation 1997;63(3):449-54.
1997: Ciavarra R P; Buhrer K; Van Rooijen N; Tedeschi B
T cell priming against vesicular stomatitis virus analyzed in situ: red pulp macrophages, but neither marginal metallophilic nor marginal zone macrophages, are required for priming CD4+ and CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(4):1749-55.
1997: Salkowski C A; Detore G; McNally R; van Rooijen N; Vogel S N
Regulation of inducible nitric oxide synthase messenger RNA expression and nitric oxide production by lipopolysaccharide in vivo: the roles of macrophages, endogenous IFN-gamma, and TNF receptor-1-mediated signaling.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(2):905-12.
1997: Wolff G; Worgall S; van Rooijen N; Song W R; Harvey B G; Crystal R G
Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ.
Journal of virology 1997;71(1):624-9.
1996: Buiting A M; Zhou F; Bakker J A; van Rooijen N; Huang L
Biodistribution of clodronate and liposomes used in the liposome mediated macrophage 'suicide' approach.
Journal of immunological methods 1996;192(1-2):55-62.
1996: van Rooijen N; Sanders A; van den Berg T K
Apoptosis of macrophages induced by liposome-mediated intracellular delivery of clodronate and propamidine.
Journal of immunological methods 1996;193(1):93-9.
1996: Van Rooijen N; Sanders A
Kupffer cell depletion by liposome-delivered drugs: comparative activity of intracellular clodronate, propamidine, and ethylenediaminetetraacetic acid.
Hepatology (Baltimore, Md.) 1996;23(5):1239-43.
1996: Buiting A M; De Rover Z; Kraal G; Van Rooijen N
Humoral immune responses against particulate bacterial antigens are dependent on marginal metallophilic macrophages in the spleen.
Scandinavian journal of immunology 1996;43(4):398-405.
1996: Boelen A; Platvoet-ter Schiphorst M C; van Rooijen N; Wiersinga W M
Selective macrophage depletion in the liver does not prevent the development of the sick euthyroid syndrome in the mouse.
European journal of endocrinology / European Federation of Endocrine Societies 1996;134(4):513-8.
1996: Wijburg O L; Heemskerk M H; Sanders A; Boog C J; Van Rooijen N
Role of virus-specific CD4+ cytotoxic T cells in recovery from mouse hepatitis virus infection.
Immunology 1996;87(1):34-41.
1996: van Rooijen N; Wijburg O L; van den Dobbelsteen G P; Sanders A
Macrophages in host defense mechanisms.
Current topics in microbiology and immunology 1996;210():159-65.
1995: Salkowski C A; Neta R; Wynn T A; Strassmann G; van Rooijen N; Vogel S N
Effect of liposome-mediated macrophage depletion on LPS-induced cytokine gene expression and radioprotection.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(6):3168-79.
1995: Fraser C C; Chen B P; Webb S; van Rooijen N; Kraal G
Circulation of human hematopoietic cells in severe combined immunodeficient mice after Cl2MDP-liposome-mediated macrophage depletion.
Blood 1995;86(1):183-92.
1995: Huitinga I; Ruuls S R; Jung S; Van Rooijen N; Hartung H P; Dijkstra C D
Macrophages in T cell line-mediated, demyelinating, and chronic relapsing experimental autoimmune encephalomyelitis in Lewis rats.
Clinical and experimental immunology 1995;100(2):344-51.
1995: Biewenga J; van der Ende M B; Krist L F; Borst A; Ghufron M; van Rooijen N
Macrophage depletion in the rat after intraperitoneal administration of liposome-encapsulated clodronate: depletion kinetics and accelerated repopulation of peritoneal and omental macrophages by administration of Freund's adjuvant.
Cell and tissue research 1995;280(1):189-96.
1995: Schotanus K; Holtkamp G M; van Rooijen N; Tilders F J; Berkenbosch F
Circulating tumor necrosis factor-alpha does not mediate endotoxin-induced hypothermia in rats.
The American journal of physiology 1995;268(4 Pt 2):R989-96.
1995: Buiting A M; De Rover Z; Van Rooijen N
Brucella abortus causes an accelerated repopulation of the spleen and liver of mice by macrophages after their liposome-mediated depletion.
Journal of medical microbiology 1995;42(2):133-40.
1995: van Rooijen N; Bakker J; Sanders A; Mellink J
Killing of Entamoeba invadens using liposome-encapsulated drugs.
Parasitology research 1995;81(3):258-61.
1994: Van Rooijen N; Sanders A
Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications.
Journal of immunological methods 1994;174(1-2):83-93.
1994: Wijffels J F; de Rover Z; Beelen R H; Kraal G; van Rooijen N
Macrophage subpopulations in the mouse spleen renewed by local proliferation.
Immunobiology 1994;191(1):52-64.
1994: Derijk R H; Van Kampen M; Van Rooijen N; Berkenbosch F
Hypothermia to endotoxin involves reduced thermogenesis, macrophage-dependent mechanisms, and prostaglandins.
The American journal of physiology 1994;266(1 Pt 2):R1-8.
1994: van Rooijen N
Liposome mediated modulation of macrophage functions.
Advances in experimental medicine and biology 1994;355():69-74.
1994: Buiting A M; Van Rooijen N
Liposome mediated depletion of macrophages: an approach for fundamental studies.
Journal of drug targeting 1994;2(5):357-62.
1993: Derijk R H; Strijbos P J; van Rooijen N; Rothwell N J; Berkenbosch F
Fever and thermogenesis in response to bacterial endotoxin involve macrophage-dependent mechanisms in rats.
The American journal of physiology 1993;265(5 Pt 2):R1179-83.
1993: Van Rooijen N
The role of the FDC-retained immune complex network and its dynamics in the activity of germinal centres.
Research in immunology 1993;144(8):545-52.
1993: van den Dobbelsteen G P; Brunekreef K; Kroes H; van Rooijen N; van Rees E P
Enhanced triggering of mucosal immune responses by reducing splenic phagocytic functions.
European journal of immunology 1993;23(7):1488-93.
1993: Buiting A M; de Rover Z; Claassen E; van Rooijen N
In vivo distribution of particulate antigens and liposomes in murine spleen. A possible role in the humoral immune response.
Immunobiology 1993;188(1-2):13-22.
1993: van Rooijen N
Extracellular and intracellular action of clodronate in osteolytic bone diseases? A hypothesis.
Calcified tissue international 1993;52(6):407-10.
1993: Dulak J; Bauer J; Döpp E A; Van Rooijen N
Immune-complex-trapping cells in the spleen of the oriental fire-bellied toad, Bombina orientalis.
Cell and tissue research 1993;271(1):155-8.
1992: van Rooijen N; Poppema A
Efficacy of various water-soluble chelator molecules in the liposome-mediated macrophage "suicide" technique.
Journal of pharmacological and toxicological methods 1992;28(4):217-21.
1992: van Rooijen N
Macrophages as accessory cells in the in vivo humoral immune response: from processing of particulate antigens to regulation by suppression.
Seminars in immunology 1992;4(4):237-45.
1992: van Rooijen N; ter Hart H; Kraal G; Kors N; Claassen E
Monoclonal antibody mediated targeting of enzymes. A comparative study using the mouse spleen as a model system.
Journal of immunological methods 1992;151(1-2):149-55.
1992: Buiting A M; van Rooijen N; Claassen E
Liposomes as antigen carriers and adjuvants in vivo.
Research in immunology 1992;143(5):541-8; discussion 578-9.
1992: Huitinga I; Damoiseaux J G; van Rooijen N; Döpp E A; Dijkstra C D
Liposome mediated affection of monocytes.
Immunobiology 1992;185(1):11-9.
1992: Derijk R H; van Rooijen N; Berkenbosch F
The role of macrophages in the hypothalamic-pituitary-adrenal activation in response to endotoxin (LPS).
Research in immunology 1992;143(2):224-9.
1991: Wijffels J F; de Rover Z; van Rooijen N; Kraal G; Beelen R H
Chronic inflammation induces the expression of dendritic cell markers not related to functional antigen presentation on peritoneal exudate macrophages.
Immunobiology 1991;184(1):83-92.
1991: Delemarre F G; Kors N; van Rooijen N
Development of antibody-forming cells in follicles of lymph nodes of mice after continuous antigenic stimulation.
Immunobiology 1991;184(1):75-82.
1991: van den Dobbelsteen G P; van Rooijen N; Sminia T; van Rees E P
The immune response in the rat to Streptococcus pneumoniae type 3 and type 4 capsular polysaccharide. Detection by double immunocytochemical staining of antibody-containing cells in situ and ELISA.
Journal of immunological methods 1991;145(1-2):93-103.
1991: Soesatyo M; Biewenga J; van Rooijen N; Kors N; Sminia T
The in situ immune response of the rat after intraperitoneal depletion of macrophages by liposome-encapsulated dichloromethylene diphosphonate.
Research in immunology 1991;142(7):533-40.
1991: Derijk R; Van Rooijen N; Tilders F J; Besedovsky H O; Del Rey A; Berkenbosch F
Selective depletion of macrophages prevents pituitary-adrenal activation in response to subpyrogenic, but not to pyrogenic, doses of bacterial endotoxin in rats.
Endocrinology 1991;129(1):330-8.
1991: Van Rooijen N
High and low cytosolic Ca2+ induced macrophage death? Hypothesis.
Cell calcium 1991;12(6):381-4.
1991: Van Rooijen N
The humoral immune response in the spleen.
Research in immunology 1991;142(4):328-30.
1991: van Rooijen N
The role of antigens, antibodies and immune complexes in the functional activity of germinal centres.
Research in immunology 1991;142(3):272-5.
1990: Delemarre F G; Kors N; van Rooijen N
Elimination of spleen and of lymph node macrophages and its difference in the effect on the immune response to particulate antigens.
Immunobiology 1990;182(1):70-8.
1990: van Rooijen N
Antigen processing and presentation in vivo: the microenvironment as a crucial factor.
Immunology today 1990;11(12):436-9.
1990: Huitinga I; van Rooijen N; de Groot C J; Uitdehaag B M; Dijkstra C D
Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages.
The Journal of experimental medicine 1990;172(4):1025-33.
1990: Laman J D; Kors N; Van Rooijen N; Claassen E
Mechanism of follicular trapping: localization of immune complexes and cell remnants after elimination and repopulation of different spleen cell populations.
Immunology 1990;71(1):57-62.
1990: Delemarre F G; Kors N; van Rooijen N
The in situ immune response in popliteal lymph nodes of mice after macrophage depletion. Differential effects of macrophages on thymus-dependent and thymus-independent immune responses.
Immunobiology 1990;180(4-5):395-404.
1990: van Rooijen N
Direct intrafollicular differentiation of memory B cells into plasma cells.
Immunology today 1990;11(5):154-7.
1990: Van Rooijen N; Kors N; vd Ende M; Dijkstra C D
Depletion and repopulation of macrophages in spleen and liver of rat after intravenous treatment with liposome-encapsulated dichloromethylene diphosphonate.
Cell and tissue research 1990;260(2):215-22.
1990: Delemarre F G; Kors N; Kraal G; van Rooijen N
Repopulation of macrophages in popliteal lymph nodes of mice after liposome-mediated depletion.
Journal of leukocyte biology 1990;47(3):251-7.
1989: Van Rooijen N
The liposome-mediated macrophage 'suicide' technique.
Journal of immunological methods 1989;124(1):1-6.
1989: Kraal G; Rodrigues H; Hoeben K; Van Rooijen N
Lymphocyte migration in the spleen: the effect of macrophage elimination.
Immunology 1989;68(2):227-32.
1989: Claassen E; Ott A; Boersma W J; Deen C; Schellekens M M; Dijkstra C D; Kors N; Van Rooijen N
Marginal zone of the murine spleen in autotransplants: functional and histological observations in the response against a thymus-independent type 2 antigen.
Clinical and experimental immunology 1989;77(3):445-51.
1989: van Rooijen N; Kors N
Effects of intracellular diphosphonates on cells of the mononuclear phagocyte system: in vivo effects of liposome-encapsulated diphosphonates on different macrophage subpopulations in the spleen.
Calcified tissue international 1989;45(3):153-6.
1989: Thepen T; Van Rooijen N; Kraal G
Alveolar macrophage elimination in vivo is associated with an increase in pulmonary immune response in mice.
The Journal of experimental medicine 1989;170(2):499-509.
1989: Su D; Van Rooijen N
The role of macrophages in the immunoadjuvant action of liposomes: effects of elimination of splenic macrophages on the immune response against intravenously injected liposome-associated albumin antigen.
Immunology 1989;66(3):466-70.
1989: Delemarre F G; Claassen E; Van Rooijen N
Primary in situ immune response in popliteal lymph nodes and spleen of mice after subcutaneous immunization with thymus-dependent or thymus-independent (type 1 and 2) antigens.
The Anatomical record 1989;223(2):152-7.
1989: van Rooijen N; Kors N; Kraal G
Macrophage subset repopulation in the spleen: differential kinetics after liposome-mediated elimination.
Journal of leukocyte biology 1989;45(2):97-104.
1988: Claassen E; Westerhof Y; Versluis B; Kors N; Schellekens M; van Rooijen N
Effects of chronic injection of sphingomyelin-containing liposomes on lymphoid and non-lymphoid cells in the spleen. Transient suppression of marginal zone macrophages.
British journal of experimental pathology 1988;69(6):865-75.
1988: Groeneveld P H; Claassen E; Kuper C F; Van Rooijen N
The role of macrophages in LPS-induced lethality and tissue injury.
Immunology 1988;63(3):521-7.
1988: van Rooijen N; Kors N
Specific antibody forming cells in lymphoid follicles of spleen: an aspect of the late immune response.
Advances in experimental medicine and biology 1988;237():221-5.
1988: van Rooijen N; Kors N; Kraal G
Characterization of cell populations, reappearing in the mouse spleen after elimination by liposome encapsulated dichloromethylene diphosphonate: reappearance of marginal zone lymphocytes is independent of marginal zone macrophages.
Advances in experimental medicine and biology 1988;237():889-93.
1988: van Rooijen N; Kors N; ter Hart H; Claassen E
In vitro and in vivo elimination of macrophage tumor cells using liposome-encapsulated dichloromethylene diphosphonate.
Virchows Archiv. B, Cell pathology including molecular pathology 1988;54(4):241-5.
1987: van Rees E P; Dijkstra C D; van Rooijen N
The early postnatal development of the primary immune response in rat popliteal lymph node, stimulated with thymus-independent type-1 and type-2 antigens.
Cell and tissue research 1987;250(3):695-9.
1987: van Rooijen N
The "in situ" immune response in lymph nodes: a review.
The Anatomical record 1987;218(4):359-64.
1987: van Rooijen N
The limitations of immunoenzyme approaches to distinguish between 'specific' and 'non-specific' antibody-forming cells, with particular respect to immunocytochemical studies on the in situ immune response.
The Histochemical journal 1987;19(6-7):369-74.
1987: van der Brugge-Gamelkoorn G J; Kors N; van Rooijen N
Development of specific antibody-forming cells in various lymphoid organs of rabbit after intravenous antigen administration.
The Anatomical record 1987;217(1):56-60.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Nico van Rooijen

Research Profile (preview)

Living Beings

Anatomy

Chemicals & Drugs

Disorders

Physiology

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Nico van Rooijen (preview)

All Publications