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Frans van Roy

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
28
Fiers, Walter
26
Berx, Geert
25
Mareel, Marc
23
van Hengel, Jolanda
18
Nollet, Friedel
18
Bruyneel, Erik
17
Beyaert, Rudi
14
Bracke, Marc
14
Mareel, Marc
12
Vermeulen, Stefan
9
Speleman, Frank
9
Staes, Katrien
9
Bonné, Stefan
8
de Bruyne, Georges
8
Kools, Patrick

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Publications

TOP 3
Vandepoele Karl; Andries Vanessa; van Roy Frans
The NBPF1 promoter has been recruited from the unrelated EVI5 gene before simian radiation.
Chastre Eric; Abdessamad Mahmoud; Kruglov Alexey; Bruyneel Erik; Bracke Marc; Di Gioia Yolande; Beckerle Mary C; van Roy Frans; Kotelevets Larissa
TRIP6, a novel molecular partner of the MAGI-1 scaffolding molecule, promotes invasiveness.
Vandewalle C; Van Roy F; Berx G
The role of the ZEB family of transcription factors in development and disease.

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All Publications

2009: Vandepoele Karl; Andries Vanessa; van Roy Frans
The NBPF1 promoter has been recruited from the unrelated EVI5 gene before simian radiation.
Molecular biology and evolution 2009;26(6):1321-32.
2009: Chastre Eric; Abdessamad Mahmoud; Kruglov Alexey; Bruyneel Erik; Bracke Marc; Di Gioia Yolande; Beckerle Mary C; van Roy Frans; Kotelevets Larissa
TRIP6, a novel molecular partner of the MAGI-1 scaffolding molecule, promotes invasiveness.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(3):916-28.
2009: Vandewalle C; Van Roy F; Berx G
The role of the ZEB family of transcription factors in development and disease.
Cellular and molecular life sciences : CMLS 2009;66(5):773-87.
2009: Hulpiau Paco; van Roy Frans
Molecular evolution of the cadherin superfamily.
The international journal of biochemistry & cell biology 2009;41(2):349-69.
2008: van Roy F; Berx G
The cell-cell adhesion molecule E-cadherin.
Cellular and molecular life sciences : CMLS 2008;65(23):3756-88.
2008: Redies Christoph; Heyder Jessica; Kohoutek Tomás; Staes Katrien; Van Roy Frans
Expression of protocadherin-1 (Pcdh1) during mouse development.
Developmental dynamics : an official publication of the American Association of Anatomists 2008;237(9):2496-505.
2008: Denayer Tinneke; Locker Morgane; Borday Caroline; Deroo Tom; Janssens Sylvie; Hecht Andreas; van Roy Frans; Perron Muriel; Vleminckx Kris
Canonical Wnt signaling controls proliferation of retinal stem/progenitor cells in postembryonic Xenopus eyes.
Stem cells (Dayton, Ohio) 2008;26(8):2063-74.
2008: Sekkali Belaïd; Tran Hong Thi; Crabbe Ellen; De Beule Christophe; Van Roy Frans; Vleminckx Kris
Chicken beta-globin insulator overcomes variegation of transgenes in Xenopus embryos.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(7):2534-40.
2008: Bonnomet A; Polette M; Strumane K; Gilles C; Dalstein V; Kileztky C; Berx G; van Roy F; Birembaut P; Nawrocki-Raby B
The E-cadherin-repressed hNanos1 gene induces tumor cell invasion by upregulating MT1-MMP expression.
Oncogene 2008;27(26):3692-9.
2008: Sklyarova Tatyana; Bonné Stefan; D'Hooge Petra; Denecker Geertrui; Goossens Steven; De Rycke Riet; Borgonie Gaetan; Bösl Michael; van Roy Frans; van Hengel Jolanda
Plakophilin-3-deficient mice develop hair coat abnormalities and are prone to cutaneous inflammation.
The Journal of investigative dermatology 2008;128(6):1375-85.
2008: Wiesner C; Winsauer G; Resch U; Hoeth M; Schmid J A; van Hengel J; van Roy F; Binder B R; de Martin R
Alpha-catulin, a Rho signalling component, can regulate NF-kappaB through binding to IKK-beta, and confers resistance to apoptosis.
Oncogene 2008;27(15):2159-69.
2008: Vandepoele Karl; Andries Vanessa; Van Roy Nadine; Staes Katrien; Vandesompele Jo; Laureys Geneviève; De Smet Els; Berx Geert; Speleman Frank; van Roy Frans
A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the human NBPF1 and ACCN1 genes.
PloS one 2008;3(5):e2207.
2007: Goossens Steven; Janssens Barbara; Bonné Stefan; De Rycke Riet; Braet Filip; van Hengel Jolanda; van Roy Frans
A unique and specific interaction between alphaT-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs.
Journal of cell science 2007;120(Pt 12):2126-36.
2007: Vandepoele Karl; van Roy Frans
Insertion of an HERV(K) LTR in the intron of NBPF3 is not required for its transcriptional activity.
Virology 2007;362(1):1-5.
2007: Wielockx Ben; Staelens Jan; Puimège Leen; Vanlaere Ineke; Van Roy Maarten; van Lint Philippe; Van Roy Frans; Libert Claude
Description and mapping of the resistance of DBA/2 mice to TNF-induced lethal shock.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(8):5069-75.
2007: Aigner Kirsten; Descovich Luise; Mikula Mario; Sultan Aneesa; Dampier Brigitta; Bonné Stefan; van Roy Frans; Mikulits Wolfgang; Schreiber Martin; Brabletz Thomas; Sommergruber Wolfgang; Schweifer Norbert; Wernitznig Andreas; Beug Hartmut; Foisner Roland; Eger Andreas
The transcription factor ZEB1 (deltaEF1) represses Plakophilin 3 during human cancer progression.
FEBS letters 2007;581(8):1617-24.
2007: Goossens Steven; Janssens Barbara; Vanpoucke Griet; De Rycke Riet; van Hengel Jolanda; van Roy Frans
Truncated isoform of mouse alphaT-catenin is testis-restricted in expression and function.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(3):647-55.
2007: van Hengel Jolanda; van Roy Frans
Diverse functions of p120ctn in tumors.
Biochimica et biophysica acta 2007;1773(1):78-88.
2006: Strumane Kristin; Bonnomet Arnaud; Stove Christophe; Vandenbroucke Roosmarijn; Nawrocki-Raby Beatrice; Bruyneel Erik; Mareel Marc; Birembaut Philippe; Berx Geert; van Roy Frans
E-cadherin regulates human Nanos1, which interacts with p120ctn and induces tumor cell migration and invasion.
Cancer research 2006;66(20):10007-15.
2006: Bredan Amin S; van Roy Frans
Writing readable prose: when planning a scientific manuscript, following a few simple rules has a large impact.
EMBO reports 2006;7(9):846-9.
2006: Bindels S; Mestdagt M; Vandewalle C; Jacobs N; Volders L; Noël A; van Roy F; Berx G; Foidart J-M; Gilles C
Regulation of vimentin by SIP1 in human epithelial breast tumor cells.
Oncogene 2006;25(36):4975-85.
2006: Mahieu Tina; Park Jin Mo; Revets Hilde; Pasche Bastian; Lengeling Andreas; Staelens Jan; Wullaert Andy; Vanlaere Ineke; Hochepied Tino; van Roy Frans; Karin Michael; Libert Claude
The wild-derived inbred mouse strain SPRET/Ei is resistant to LPS and defective in IFN-beta production.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(7):2292-7.
2006: Vlieghe Dominique; Sandelin Albin; De Bleser Pieter J; Vleminckx Kris; Wasserman Wyeth W; van Roy Frans; Lenhard Boris
A new generation of JASPAR, the open-access repository for transcription factor binding site profiles.
Nucleic acids research 2006;34(Database issue):D95-7.
2006: Denayer Tinneke; Van Roy Frans; Vleminckx Kris
In vivo tracing of canonical Wnt signaling in Xenopus tadpoles by means of an inducible transgenic reporter tool.
FEBS letters 2006;580(2):393-8.
2005: van Roy Frans M; McCrea Pierre D
A role for Kaiso-p120ctn complexes in cancer?
Nature reviews. Cancer 2005;5(12):956-64.
2005: Bogaerts Sven; Vanlandschoot Ann; van Hengel Jolanda; van Roy Frans
Nuclear translocation of alphaN-catenin by the novel zinc finger transcriptional repressor ZASC1.
Experimental cell research 2005;311(1):1-13.
2005: Vandepoele Karl; Van Roy Nadine; Staes Katrien; Speleman Frank; van Roy Frans
A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.
Molecular biology and evolution 2005;22(11):2265-74.
2005: De Craene Bram; Gilbert Barbara; Stove Christophe; Bruyneel Erik; van Roy Frans; Berx Geert
The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program.
Cancer research 2005;65(14):6237-44.
2005: Vanhalst K; Kools P; Staes K; van Roy F; Redies C
delta-Protocadherins: a gene family expressed differentially in the mouse brain.
Cellular and molecular life sciences : CMLS 2005;62(11):1247-59.
2005: De Craene Bram; van Roy Frans; Berx Geert
Unraveling signalling cascades for the Snail family of transcription factors.
Cellular signalling 2005;17(5):535-47.
2005: Soubry Adelheid; van Hengel Jolanda; Parthoens Eef; Colpaert Cecile; Van Marck Eric; Waltregny David; Reynolds Albert B; van Roy Frans
Expression and nuclear location of the transcriptional repressor Kaiso is regulated by the tumor microenvironment.
Cancer research 2005;65(6):2224-33.
2005: Kotelevets Larissa; van Hengel Jolanda; Bruyneel Erik; Mareel Marc; van Roy Frans; Chastre Eric
Implication of the MAGI-1b/PTEN signalosome in stabilization of adherens junctions and suppression of invasiveness.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(1):115-7.
2005: Goossens Steven; van Roy Frans
Cadherin-mediated cell-cell adhesion in the testis.
Frontiers in bioscience : a journal and virtual library 2005;10():398-419.
2005: Vandewalle Cindy; Comijn Joke; De Craene Bram; Vermassen Petra; Bruyneel Erik; Andersen Henriette; Tulchinsky Eugene; Van Roy Frans; Berx Geert
SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions.
Nucleic acids research 2005;33(20):6566-78.
2004: Deroo Tom; Denayer Tinneke; Van Roy Frans; Vleminckx Kris
Global inhibition of Lef1/Tcf-dependent Wnt signaling at its nuclear end point abrogates development in transgenic Xenopus embryos.
The Journal of biological chemistry 2004;279(49):50670-5.
2004: van Dijk Marie; Mulders Joyce; Könst Andrea; Janssens Barbara; van Roy Frans; Blankenstein Marinus; Oudejans Cees
Differential downregulation of alphaT-catenin expression in placenta: trophoblast cell type-dependent imprinting of the CTNNA3 gene.
Gene expression patterns : GEP 2004;5(1):61-5.
2004: Ciesiolka Malgorzata; Delvaeye Mieke; Van Imschoot Griet; Verschuere Veerle; McCrea Pierre; van Roy Frans; Vleminckx Kris
p120 catenin is required for morphogenetic movements involved in the formation of the eyes and the craniofacial skeleton in Xenopus.
Journal of cell science 2004;117(Pt 18):4325-39.
2004: Staelens Jan; Puimège Leen; Mahieu Tina; Pynaert Gwenda; Hochepied Tino; Vandenabeele Annelies; Grooten Johan; Kontoyiannis Dimitris; Van Roy Frans; Kollias George; Libert Claude
Response of TNF-hyporesponsive SPRET/Ei mice in models of inflammatory disorders.
Mammalian genome : official journal of the International Mammalian Genome Society 2004;15(7):537-43.
2004: De Preter Katleen; Pattyn Filip; Berx Geert; Strumane Kristin; Menten Björn; Van Roy Frans; De Paepe Anne; Speleman Frank; Vandesompele Jo
Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons.
BMC genomics 2004;5(1):11.
2004: André Frédéric; Janssens Barbara; Bruyneel Erik; van Roy Frans; Gespach Christian; Mareel Marc; Bracke Marc
Alpha-catenin is required for IGF-I-induced cellular migration but not invasion in human colonic cancer cells.
Oncogene 2004;23(6):1177-86.
2004: Vanpoucke Griet; Goossens Steven; De Craene Bram; Gilbert Barbara; van Roy Frans; Berx Geert
GATA-4 and MEF2C transcription factors control the tissue-specific expression of the alphaT-catenin gene CTNNA3.
Nucleic acids research 2004;32(14):4155-65.
2004: Hochepied Tino; Schoonjans Luc; Staelens Jan; Kreemers Veerle; Danloy Sophie; Puimège Leen; Collen Désiré; Van Roy Frans; Libert Claude
Breaking the species barrier: derivation of germline-competent embryonic stem cells from Mus spretus x C57BL/6 hybrids.
Stem cells (Dayton, Ohio) 2004;22(4):441-7.
2003: Debruyne Philip R; Vermeulen Stefan J; Berx Geert; Pocard Marc; Correia da Rocha Ana-Sofia; Li Xuedong; Cirnes Luis; Poupon Marie-France; van Roy Frans M; Mareel Marc M
Functional and molecular characterization of the epithelioid to round transition in human colorectal cancer LoVo cells.
Oncogene 2003;22(46):7199-208.
2003: Nawrocki-Raby Béatrice; Gilles Christine; Polette Myriam; Martinella-Catusse Corinne; Bonnet Noël; Puchelle Edith; Foidart Jean-Michel; Van Roy Frans; Birembaut Philippe
E-Cadherin mediates MMP down-regulation in highly invasive bronchial tumor cells.
The American journal of pathology 2003;163(2):653-61.
2003: Bonné Stefan; Gilbert Barbara; Hatzfeld Mechthild; Chen Xinyu; Green Kathleen J; van Roy Frans
Defining desmosomal plakophilin-3 interactions.
The Journal of cell biology 2003;161(2):403-16.
2003: Colpaert C G; Vermeulen P B; Benoy I; Soubry A; van Roy F; van Beest P; Goovaerts G; Dirix L Y; van Dam P; Fox S B; Harris A L; van Marck E A
Inflammatory breast cancer shows angiogenesis with high endothelial proliferation rate and strong E-cadherin expression.
British journal of cancer 2003;88(5):718-25.
2003: Janssens Barbara; Mohapatra Bhagyalaxmi; Vatta Matteo; Goossens Steven; Vanpoucke Griet; Kools Patrick; Montoye Tony; van Hengel Jolanda; Bowles Neil E; van Roy Frans; Towbin Jeffrey A
Assessment of the CTNNA3 gene encoding human alpha T-catenin regarding its involvement in dilated cardiomyopathy.
Human genetics 2003;112(3):227-36.
2002: Ireton Renee C; Davis Michael A; van Hengel Jolanda; Mariner Deborah J; Barnes Kirk; Thoreson Molly A; Anastasiadis Panos Z; Matrisian Linsey; Bundy Linda M; Sealy Linda; Gilbert Barbara; van Roy Frans; Reynolds Albert B
A novel role for p120 catenin in E-cadherin function.
The Journal of cell biology 2002;159(3):465-76.
2002: Van Roy Nadine; Vandesompele Jo; Berx Geert; Staes Katrien; Van Gele Mireille; De Smet Els; De Paepe Anne; Laureys Geneviève; van der Drift Pauline; Versteeg Rogier; Van Roy Frans; Speleman Frank
Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type 1 patients.
Genes, chromosomes & cancer 2002;35(2):113-20.
2002: Müller Nicole; Reinacher-Schick Anke; Baldus Stephan; van Hengel Jolanda; Berx Geert; Baar Anke; van Roy Frans; Schmiegel Wolff; Schwarte-Waldhoff Irmgard
Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells.
Oncogene 2002;21(39):6049-58.
2002: Staelens Jan; Wielockx Ben; Puimège Leen; Van Roy Frans; Guénet Jean-Louis; Libert Claude
Hyporesponsiveness of SPRET/Ei mice to lethal shock induced by tumor necrosis factor and implications for a TNF-based antitumor therapy.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(14):9340-5.
2002: Vanpoucke Griet; Nollet Friedel; Tejpar Sabine; Cassiman Jean-Jacques; van Roy Frans
The human alphaE-catenin gene CTNNA1: mutational analysis and rare occurrence of a truncated splice variant.
Biochimica et biophysica acta 2002;1574(3):262-8.
2002: Chen Xinyu; Bonne Stefan; Hatzfeld Mechthild; van Roy Frans; Green Kathleen J
Protein binding and functional characterization of plakophilin 2. Evidence for its diverse roles in desmosomes and beta -catenin signaling.
The Journal of biological chemistry 2002;277(12):10512-22.
2002: Kim Si Wan; Fang Xiang; Ji Hong; Paulson Alicia F; Daniel Juliet M; Ciesiolka Malgorzata; van Roy Frans; McCrea Pierre D
Isolation and characterization of XKaiso, a transcriptional repressor that associates with the catenin Xp120(ctn) in Xenopus laevis.
The Journal of biological chemistry 2002;277(10):8202-8.
2001: Kotelevets L; van Hengel J; Bruyneel E; Mareel M; van Roy F; Chastre E
The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness.
The Journal of cell biology 2001;155(7):1129-35.
2001: Janssens B; Goossens S; Staes K; Gilbert B; van Hengel J; Colpaert C; Bruyneel E; Mareel M; van Roy F
alphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion.
Journal of cell science 2001;114(Pt 17):3177-88.
2001: Nawrocki Raby B; Polette M; Gilles C; Clavel C; Strumane K; Matos M; Zahm J M; Van Roy F; Bonnet N; Birembaut P
Quantitative cell dispersion analysis: new test to measure tumor cell aggressiveness.
International journal of cancer. Journal international du cancer 2001;93(5):644-52.
2001: Comijn J; Berx G; Vermassen P; Verschueren K; van Grunsven L; Bruyneel E; Mareel M; Huylebroeck D; van Roy F
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion.
Molecular cell 2001;7(6):1267-78.
2001: Clavel C E; Nollet F; Berx G; Tejpar S; Nawrocki-Raby B; Kaplan H H; van Roy F M; Birembaut P L
Expression of the E-cadherin-catenin complex in lung neuroendocrine tumours.
The Journal of pathology 2001;194(1):20-6.
2001: Vanhalst K; Kools P; Vanden Eynde E; van Roy F
The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.
FEBS letters 2001;495(1-2):120-5.
2000: Kools P; Van Imschoot G; van Roy F
Characterization of three novel human cadherin genes (CDH7, CDH19, and CDH20) clustered on chromosome 18q22-q23 and with high homology to chicken cadherin-7.
Genomics 2000;68(3):283-95.
2000: Keilhack H; Hellman U; van Hengel J; van Roy F; Godovac-Zimmermann J; Böhmer F D
The protein-tyrosine phosphatase SHP-1 binds to and dephosphorylates p120 catenin.
The Journal of biological chemistry 2000;275(34):26376-84.
2000: Nollet F; Kools P; van Roy F
Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.
Journal of molecular biology 2000;299(3):551-72.
2000: Bonné S; van Hengel J; van Roy F
Assignment of the plakophilin-2 gene (PKP2) and a plakophilin-2 pseudogene (PKP2P1) to human chromosome bands 12p11 and 12p13, respectively, by in situ hybridization.
Cytogenetics and cell genetics 2000;88(3-4):286-7.
1999: Tejpar S; Nollet F; Li C; Wunder J S; Michils G; dal Cin P; Van Cutsem E; Bapat B; van Roy F; Cassiman J J; Alman B A
Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor).
Oncogene 1999;18(47):6615-20.
1999: Janssens B; Staes K; van Roy F
Human alpha-catulin, a novel alpha-catenin-like molecule with conserved genomic structure, but deviating alternative splicing.
Biochimica et biophysica acta 1999;1447(2-3):341-7.
1999: Nollet F; Berx G; van Roy F
The role of the E-cadherin/catenin adhesion complex in the development and progression of cancer.
Molecular cell biology research communications : MCBRC 1999;2(2):77-85.
1999: van Hengel J; Vanhoenacker P; Staes K; van Roy F
Nuclear localization of the p120(ctn) Armadillo-like catenin is counteracted by a nuclear export signal and by E-cadherin expression.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(14):7980-5.
1999: Bonné S; van Hengel J; Nollet F; Kools P; van Roy F
Plakophilin-3, a novel armadillo-like protein present in nuclei and desmosomes of epithelial cells.
Journal of cell science 1999;112 ( Pt 14)():2265-76.
1999: Kools P; Vanhalst K; Van den Eynde E; van Roy F
The human cadherin-10 gene: complete coding sequence, predominant expression in the brain, and mapping on chromosome 5p13-14.
FEBS letters 1999;452(3):328-34.
1999: Vermeulen S J; Nollet F; Teugels E; Vennekens K M; Malfait F; Philippé J; Speleman F; Bracke M E; van Roy F M; Mareel M M
The alphaE-catenin gene (CTNNA1) acts as an invasion-suppressor gene in human colon cancer cells.
Oncogene 1999;18(4):905-15.
1999: Vermeulen S J; Debruyne P R; Marra G; Speleman F P; Boukamp P; Jiricny J; Cuthbert A P; Newbold R F; Nollet F H; van Roy F M; Mareel M M
hMSH6 deficiency and inactivation of the alphaE-catenin invasion-suppressor gene in HCT-8 colon cancer cells.
Clinical & experimental metastasis 1999;17(8):663-8.
1999: Kools P; Vanhalst K; van Roy F
Assignment of cadherin-4 (R-cadherin, CDH4) to human chromosome band 20q13.3.
Cytogenetics and cell genetics 1999;86(1):26-7.
1998: Nawrocki B; Polette M; Van Hengel J; Tournier J M; Van Roy F; Birembault P
Cytoplasmic redistribution of E-cadherin-catenin adhesion complex is associated with down-regulated tyrosine phosphorylation of E-cadherin in human bronchopulmonary carcinomas.
The American journal of pathology 1998;153(5):1521-30.
1998: Vermeulen S J; Chen T R; Speleman F; Nollet F; Van Roy F M; Mareel M M
Did the four human cancer cell lines DLD-1, HCT-15, HCT-8, and HRT-18 originate from one and the same patient?
Cancer genetics and cytogenetics 1998;107(1):76-9.
1998: Keirsebilck A; Bonné S; Bruyneel E; Vermassen P; Lukanidin E; Mareel M; van Roy F
E-cadherin and metastasin (mts-1/S100A4) expression levels are inversely regulated in two tumor cell families.
Cancer research 1998;58(20):4587-91.
1998: Bonné S; van Hengel J; van Roy F
Chromosomal mapping of human armadillo genes belonging to the p120(ctn)/plakophilin subfamily.
Genomics 1998;51(3):452-4.
1998: Keirsebilck A; Bonné S; Staes K; van Hengel J; Nollet F; Reynolds A; van Roy F
Molecular cloning of the human p120ctn catenin gene (CTNND1): expression of multiple alternatively spliced isoforms.
Genomics 1998;50(2):129-46.
1998: Keirsebilck A; Van Hoorde L; Gao Y; De Bruyne G; Bruyneel E; Vermassen P; Mareel M; van Roy F
Mechanisms of downregulation of transfected E-cadherin cDNA during formation of invasive tumors in syngeneic mice.
Invasion & metastasis 1998;18(1):44-56.
1998: Berx G; Nollet F; van Roy F
Dysregulation of the E-cadherin/catenin complex by irreversible mutations in human carcinomas.
Cell adhesion and communication 1998;6(2-3):171-84.
1998: Berx G; Becker K F; Höfler H; van Roy F
Mutations of the human E-cadherin (CDH1) gene.
Human mutation 1998;12(4):226-37.
1997: Vermeulen S J; Nollet F; Teugels E; Philippe J; Speleman F; van Roy F M; Bracke M E; Mareel M M
Mutation of alpha-catenin results in invasiveness of human HCT-8 colon cancer cells.
Annals of the New York Academy of Sciences 1997;833():186-9.
1997: Berx G; Nollet F; Strumane K; van Roy F
An efficient and reliable multiplex PCR-SSCP mutation analysis test applied to the human E-cadherin gene.
Human mutation 1997;9(6):567-74.
1997: Empereur S; Djelloul S; Di Gioia Y; Bruyneel E; Mareel M; Van Hengel J; Van Roy F; Comoglio P; Courtneidge S; Paraskeva C; Chastre E; Gespach C
Progression of familial adenomatous polyposis (FAP) colonic cells after transfer of the src or polyoma middle T oncogenes: cooperation between src and HGF/Met in invasion.
British journal of cancer 1997;75(2):241-50.
1996: Berx G; Cleton-Jansen A M; Strumane K; de Leeuw W J; Nollet F; van Roy F; Cornelisse C
E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain.
Oncogene 1996;13(9):1919-25.
1996: Vermeulen S; Van Marck V; Van Hoorde L; Van Roy F; Bracke M; Mareel M
Regulation of the invasion suppressor function of the cadherin/catenin complex.
Pathology, research and practice 1996;192(7):694-707.
1996: Mareel M; Berx G; Van Roy F; Bracke M
Cadherin/catenin complex: a target for antiinvasive therapy?
Journal of cellular biochemistry 1996;61(4):524-30.
1996: Leppä S; Vleminckx K; Van Roy F; Jalkanen M
Syndecan-1 expression in mammary epithelial tumor cells is E-cadherin-dependent.
Journal of cell science 1996;109 ( Pt 6)():1393-403.
1996: Van den Broecke C; Vleminckx K; De Bruyne G; Van Hoorde L; Vakaet L; Van Roy F; Mareel M
Morphotypic plasticity in vitro and in nude mice of epithelial mouse mammary cells (NMuMG) displaying an epithelioid (e) or a fibroblastic (f) morphotype in culture.
Clinical & experimental metastasis 1996;14(3):282-96.
1996: Nollet F; Berx G; Molemans F; van Roy F
Genomic organization of the human beta-catenin gene (CTNNB1).
Genomics 1996;32(3):413-24.
1995: Berx G; Cleton-Jansen A M; Nollet F; de Leeuw W J; van de Vijver M; Cornelisse C; van Roy F
E-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers.
The EMBO journal 1995;14(24):6107-15.
1995: Vermeulen S J; Bruyneel E A; van Roy F M; Mareel M M; Bracke M E
Activation of the E-cadherin/catenin complex in human MCF-7 breast cancer cells by all-trans-retinoic acid.
British journal of cancer 1995;72(6):1447-53.
1995: Vermeulen S J; Bruyneel E A; Bracke M E; De Bruyne G K; Vennekens K M; Vleminckx K L; Berx G J; van Roy F M; Mareel M M
Transition from the noninvasive to the invasive phenotype and loss of alpha-catenin in human colon cancer cells.
Cancer research 1995;55(20):4722-8.
1995: Nollet F; van Hengel J; Berx G; Molemans F; van Roy F
Isolation and characterization of a human pseudogene (CTNNAP1) for alpha E-catenin (CTNNA1): assignment of the pseudogene to 5q22 and the alpha E-catenin gene to 5q31.
Genomics 1995;26(2):410-3.
1995: Berx G; Staes K; van Hengel J; Molemans F; Bussemakers M J; van Bokhoven A; van Roy F
Cloning and characterization of the human invasion suppressor gene E-cadherin (CDH1).
Genomics 1995;26(2):281-9.
1995: van Hengel J; Nollet F; Berx G; van Roy N; Speleman F; van Roy F
Assignment of the human beta-catenin gene (CTNNB1) to 3p22-->p21.3 by fluorescence in situ hybridization.
Cytogenetics and cell genetics 1995;70(1-2):68-70.
1994: Vandenbossche G M; De Bruyne G K; Bruyneel E A; Clemminck G; Vleminckx K; Van Roy F M; Mareel M M
Micro-encapsulation of MDCK-ras-e cells prevents loss of E-cadherin invasion-suppressor function in vivo.
International journal of cancer. Journal international du cancer 1994;57(1):73-80.
1994: Vleminckx K L; Deman J J; Bruyneel E A; Vandenbossche G M; Keirsebilck A A; Mareel M M; van Roy F M
Enlarged cell-associated proteoglycans abolish E-cadherin functionality in invasive tumor cells.
Cancer research 1994;54(4):873-7.
1994: Mareel M; Vleminckx K; Vermeulen S; Yan G; Bracke M; van Roy F
Downregulation in vivo of the invasion-suppressor molecule E-cadherin in experimental and clinical cancer.
Princess Takamatsu symposia 1994;24():63-80.
1993: Chastre E; Empereur S; Di Gioia Y; el Mahdani N; Mareel M; Vleminckx K; Van Roy F; Bex V; Emami S; Spandidos D A
Neoplastic progression of human and rat intestinal cell lines after transfer of the ras and polyoma middle T oncogenes.
Gastroenterology 1993;105(6):1776-89.
1993: Bracke M E; Vyncke B M; Bruyneel E A; Vermeulen S J; De Bruyne G K; Van Larebeke N A; Vleminckx K; Van Roy F M; Mareel M M
Insulin-like growth factor I activates the invasion suppressor function of E-cadherin in MCF-7 human mammary carcinoma cells in vitro.
British journal of cancer 1993;68(2):282-9.
1993: Beyaert R; Heyninck K; De Valck D; Boeykens F; van Roy F; Fiers W
Enhancement of tumor necrosis factor cytotoxicity by lithium chloride is associated with increased inositol phosphate accumulation.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(1):291-300.
1993: Beyaert R; Vanhaesebroeck B; Heyninck K; Boone E; De Valck D; Schulze-Osthoff K; Haegeman G; Van Roy F; Fiers W
Sensitization of tumor cells to tumor necrosis factor action by the protein kinase inhibitor staurosporine.
Cancer research 1993;53(11):2623-30.
1993: Vanhaesebroeck B; Reed J C; De Valck D; Grooten J; Miyashita T; Tanaka S; Beyaert R; Van Roy F; Fiers W
Effect of bcl-2 proto-oncogene expression on cellular sensitivity to tumor necrosis factor-mediated cytotoxicity.
Oncogene 1993;8(4):1075-81.
1993: De Valck D; Beyaert R; Van Roy F; Fiers W
Tumor necrosis factor cytotoxicity is associated with phospholipase D activation.
European journal of biochemistry / FEBS 1993;212(2):491-7.
1992: Beyaert R; Schulze-Osthoff K; Van Roy F; Fiers W
Synergistic induction of interleukin-6 by tumor necrosis factor and lithium chloride in mice: possible role in the triggering and exacerbation of psoriasis by lithium treatment.
European journal of immunology 1992;22(8):2181-4.
1992: Vanhaesebroeck B; Decoster E; Van Ostade X; Van Bladel S; Lenaerts A; Van Roy F; Fiers W
Expression of an exogenous tumor necrosis factor (TNF) gene in TNF-sensitive cell lines confers resistance to TNF-mediated cell lysis.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(9):2785-94.
1992: Mareel M; Vleminckx K; Vermeulen S; Gao Y; Vakaet L; Bracke M; van Roy F
Homotypic cell-cell adhesion molecules and tumor invasion.
Progress in histochemistry and cytochemistry 1992;26(1-4):95-106.
1992: Mareel M; Vleminckx K; Vermeulen S; Bracke M; Van Roy F
E-cadherin expression: a counterbalance for cancer cell invasion.
Bulletin du cancer 1992;79(4):347-55.
1991: Coopman P; Verhasselt B; Bracke M; De Bruyne G; Castronovo V; Sobel M; Foidart J M; Van Roy F; Mareel M
Arrest of MCF-7 cell migration by laminin in vitro: possible mechanisms.
Clinical & experimental metastasis 1991;9(5):469-84.
1991: Vleminckx K; Vakaet L; Mareel M; Fiers W; van Roy F
Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role.
Cell 1991;66(1):107-19.
1991: Beyaert R; Schulze-Osthoff K; Van Roy F; Fiers W
Lithium chloride potentiates tumor necrosis factor-induced and interleukin 1-induced cytokine and cytokine receptor expression.
Cytokine 1991;3(4):284-91.
1991: Vanhaesebroeck B; Van Bladel S; Lenaerts A; Suffys P; Beyaert R; Lucas R; Van Roy F; Fiers W
Two discrete types of tumor necrosis factor-resistant cells derived from the same cell line.
Cancer research 1991;51(9):2469-77.
1991: Mareel M M; Behrens J; Birchmeier W; De Bruyne G K; Vleminckx K; Hoogewijs A; Fiers W C; Van Roy F M
Down-regulation of E-cadherin expression in Madin Darby canine kidney (MDCK) cells inside tumors of nude mice.
International journal of cancer. Journal international du cancer 1991;47(6):922-8.
1991: Vanhaesebroeck B; Mareel M; Van Roy F; Grooten J; Fiers W
Expression of the tumor necrosis factor gene in tumor cells correlates with reduced tumorigenicity and reduced invasiveness in vivo.
Cancer research 1991;51(8):2229-38.
1991: Coopman P J; Bracke M E; Lissitzky J C; De Bruyne G K; Van Roy F M; Foidart J M; Mareel M M
Influence of basement membrane molecules on directional migration of human breast cell lines in vitro.
Journal of cell science 1991;98 ( Pt 3)():395-401.
1991: Beyaert R; De Potter C; Vanhaesebroeck B; Van Roy F; Fiers W
Induction of inflammatory cell infiltration and necrosis in normal mouse skin by the combined treatment of tumor necrosis factor and lithium chloride.
The American journal of pathology 1991;138(3):727-39.
1991: Suffys P; Beyaert R; De Valck D; Vanhaesebroeck B; Van Roy F; Fiers W
Tumour-necrosis-factor-mediated cytotoxicity is correlated with phospholipase-A2 activity, but not with arachidonic acid release per se.
European journal of biochemistry / FEBS 1991;195(2):465-75.
1991: Vakaet L; Vleminckx K; Van Roy F; Mareel M
Numerical evaluation of the invasion of closely related cell lines into collagen type I gels.
Invasion & metastasis 1991;11(5):249-60.
1990: Van Roy F; Mareel M; Vleminckx K; Beyaert R; Fiers W; Devleeschouwer N; Muquardt C; Legros N; Bracke M; Leclercq G
Hormone sensitivity in vitro and in vivo of v-ras-transfected MCF-7 cell derivatives.
International journal of cancer. Journal international du cancer 1990;46(3):522-32.
1990: Vanhaesebroeck B; Timmers H T; Pronk G J; van Roy F; Van der Eb A J; Fiers W
Modulation of cellular susceptibility to the cytotoxic/cytostatic action of tumor necrosis factor by adenovirus E1 gene expression is cell type-dependent.
Virology 1990;176(2):362-8.
1990: Beyaert R; Suffys P; Van Roy F; Fiers W
Inhibition by glucocorticoids of tumor necrosis factor-mediated cytotoxicity. Evidence against lipocortin involvement.
FEBS letters 1990;262(1):93-6.
1990: Van Roy F; Liebaut G; Mareel M; Fiers W
Partial transformation of human tumor cell lines showing defective interaction between unusual p53 gene product and SV40 large-T antigen.
Oncogene 1990;5(2):207-18.
1990: Vanhaesebroeck B; Cragoe E J; Pouysségur J; Beyaert R; Van Roy F; Fiers W
Cytotoxic activity of tumor necrosis factor is inhibited by amiloride derivatives without involvement of the Na+/H+ antiporter.
FEBS letters 1990;261(2):319-22.
1989: Beyaert R; Vanhaesebroeck B; Suffys P; Van Roy F; Fiers W
Lithium chloride potentiates tumor necrosis factor-mediated cytotoxicity in vitro and in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(23):9494-8.
1989: Van Roy F M; Coopman P; Suffys P; Liebaut G; Vleminckx K; Gao J; Dragonetti C H; Fiers W; Mareel M M
Effect of oncogene transfection or passage in vivo on malignant phenotypes of rat2 cells.
Anticancer research 1989;9(6):1553-64.
1989: Coopman P; Van Roy F; Dragonetti C; Gao J; Fiers W; Meneguzzi G; Mareel M
Tumorigenicity, invasiveness and metastatic capability of FR3T3 rat cells before and after transfection with bovine papilloma virus type 1 DNA.
Clinical & experimental metastasis 1989;7(1):69-84.
1989: Suffys P; Beyaert R; Van Roy F; Fiers W
TNF in combination with interferon-gamma is cytotoxic to normal, untransformed mouse and rat embryo fibroblast-like cells.
Anticancer research 1989;9(1):167-71.
1988: Suffys P; Beyaert R; Van Roy F; Fiers W
Involvement of a serine protease in tumour-necrosis-factor-mediated cytotoxicity.
European journal of biochemistry / FEBS 1988;178(1):257-65.
1988: Suffys P; Van Roy F; Fiers W
Tumor necrosis factor and interleukin 1 activate phospholipase in rat chondrocytes.
FEBS letters 1988;232(1):24-8.
1988: Mareel M; van Roy F; Bruyneel E; Bolscher J; Schallier D; de Mets M
Molecular biology of minimal invasion.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1988;106():14-20.
1987: Suffys P; Beyaert R; Van Roy F; Fiers W
Reduced tumour necrosis factor-induced cytotoxicity by inhibitors of the arachidonic acid metabolism.
Biochemical and biophysical research communications 1987;149(2):735-43.
1987: Fiers W; Beyaert R; Brouckaert P; Everaert B; Suffys P; Tavernier J; Van Haesebroeck B; Van Roy F
Tumor necrosis factor: a potential antitumor agent?
Journal of interferon research 1987;7(5):627-34.
1987: Gao J; Van Roy F; Messiaen L; Cosaert J; Liebaut G; Coopman P; Fiers W; Mareel M
Pathology of tumours produced in syngeneic Fischer rats by fibroblast-like cells before and after transfection with oncogenes.
Pathology, research and practice 1987;182(1):48-57.
1987: Fiers W; Brouckaert P; Goldberg A L; Kettelhut I; Suffys P; Tavernier J; Vanhaesebroeck B; Van Roy F
Structure-function relationship of tumour necrosis factor and its mechanism of action.
Ciba Foundation symposium 1987;131():109-23.
1986: Van Roy F M; Messiaen L; Liebaut G; Gao J; Dragonetti C H; Fiers W C; Mareel M M
Invasiveness and metastatic capability of rat fibroblast-like cells before and after transfection with immortalizing and transforming genes.
Cancer research 1986;46(9):4787-95.

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