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H K F Van Saene

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L Silvestri; N Taylor; C Negri; D F Zandstra; H K F Van Saene
Inappropriate dose of enteral antimicrobials promotes resistance.
S C Donnell; N Taylor; H K F Van Saene
Randomized clinical trial of glutamine-supplemented versus standard parenteral nutrition in infants with surgical gastrointestinal disease (Br J Surg 2012; 99: 929-938).
Durk F Zandstra; Francisco Abecasis; Vladimir Damjanovic; Luciano Silvestri; Nia Taylor; H K F Van Saene
For control of colonisation with extended-spectrum β-lactamase-producing bacteria, SDD does work.

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All Publications

2013: L Silvestri; N Taylor; C Negri; D F Zandstra; H K F Van Saene
Inappropriate dose of enteral antimicrobials promotes resistance.
Journal of clinical microbiology 2013;51(5):1644.
2013: S C Donnell; N Taylor; H K F Van Saene
Randomized clinical trial of glutamine-supplemented versus standard parenteral nutrition in infants with surgical gastrointestinal disease (Br J Surg 2012; 99: 929-938).
The British journal of surgery 2013;100(6):841.
2013: Durk F Zandstra; Francisco Abecasis; Vladimir Damjanovic; Luciano Silvestri; Nia Taylor; H K F Van Saene
For control of colonisation with extended-spectrum β-lactamase-producing bacteria, SDD does work.
Intensive care medicine 2013;39(3):539.
2012: L Silvestri; N Taylor; M A De La Cal; A J Petros; J H Rommes; H K F Van Saene
Why are we still mesmerized by the old fashioned Medicine Man?
Minerva anestesiologica 2012;78(12):1415.
2012: H K F Van Saene; M A de la Cal; A J Petros; L Silvestri; N Taylor; D F Zandstra
Selective decontamination and ecology.
Anaerobe 2012;18(3):361-2.
2012: L Silvestri; N Taylor; A J Petros; D F Zandstra; H K F Van Saene
Gravity may be the law, but it does not impact critical illness related carriage in overgrowth.
Minerva anestesiologica 2012;78(4):507-8; author reply 509-10.
2012: L Silvestri; H K F Van Saene
Selective decontamination of the digestive tract: an update of the evidence.
HSR proceedings in intensive care & cardiovascular anesthesia 2012;4(1):21-9.
2011: A J Petros; J H Rommes; L Silvestri; N Taylor; H K F Van Saene
Early steroid therapy for patients with H1N1 influenza A virus infection.
Intensive care medicine 2011;37(9):1563-4; author reply 1565.
2011: Durk F Zandstra; H K F Van Saene
Selective decontamination of the digestive tract as infection prevention in the critically ill. A level 1 evidence-based strategy.
Minerva anestesiologica 2011;77(2):212-9.
2010: D F Zandstra; A J Petros; L Silvestri; M A de la Cal; N Taylor; V Damjanovic; H K F Van Saene
Selective decontamination of the digestive tract: selectivity is not required.
Intensive care medicine 2010;36(10):1783-4.
2010: L Silvestri; H K F Van Saene; S Tomasino; N Taylor
Current status on VAP prevention: evidence-based medicine makes the ethics of withholding SDD questionable.
Journal of clinical monitoring and computing 2010;24(4):305-6.
2010: Marino Viviani; H K F Van Saene; Federica Edith Pisa; Umberto Lucangelo; L Silvestri; E Momesso; Giorgio Berlot
The role of admission surveillance cultures in patients requiring prolonged mechanical ventilation in the intensive care unit.
Anaesthesia and intensive care 2010;38(2):325-35.
2010: L Silvestri; A Solidoro; M Milanese; H K F Van Saene; F Fontana; D Gregori; A Gullo
Topical oropharyngeal vancomycin to control methicillin-resistant Staphylococcus aureus lower airway infection in ventilated patients.
Minerva anestesiologica 2010;76(3):193-202.
2010: V Damjanovic; C M Damjanovic; N Taylor; H K F Van Saene
Comment on reply of Miranda et al., Re: 'is the endogenous pathogenesis of Candida parapsilosis infection underreported?'.
The Journal of hospital infection 2010;74(2):187-8; author reply 188-9.
2009: V Damjanovic; N Taylor; H K F Van Saene
Origin of epidemic clones of acinetobacter in the critically ill.
The Journal of hospital infection 2009;73(3):285-6; author reply 286-7.
2009: V Damjanovic; C M Damjanovic; N Taylor; H K F Van Saene
Is the endogenous pathogenesis of Candida parapsilosis infection underreported?
The Journal of hospital infection 2009;73(1):93-4.
2009: Paloma García Hierro; Miguel A de la Cal; H K F Van Saene; Luciano Silvestri
[A new clinical trial with selective digestive decontamination].
Medicina intensiva / Sociedad Española de Medicina Intensiva y Unidades Coronarias 2009;33(6):297-300.
2009: Kentigern Thorburn; Michelle Jardine; Nia Taylor; Nicola Reilly; Richard E Sarginson; H K F Van Saene
Antibiotic-resistant bacteria and infection in children with cerebral palsy requiring mechanical ventilation.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2009;10(2):222-6.
2009: Luciano Silvestri; H K F Van Saene; Marco Milanese; Eraldo Zei; Miranda Blazic
Prevention of ventilator-associated pneumonia by use of oral chlorhexidine.
Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 2009;30(1):101-2; author reply 102-3.
2008: M Viviani; L Silvestri; H K F Van Saene; D F Zandstra; G Berlot; A Gullo
My brother has severe sepsis. Should he receive selective decontamination of the digestive tract (SDD)?
Minerva anestesiologica 2008;74(9):507.
2008: Andy J Petros; R E Sarginson; M Ashworth; N Reilly; J J M van Saene; H K F Van Saene; D F Zandstra
Selective decontamination is not sticky.
Intensive care medicine 2008;34(9):1734-5; author reply 1736.
2008: L Silvestri; H K F Van Saene; M A de la Cal; R E Sarginson; C Thomann
Prevention of ventilator-associated pneumonia by selective decontamination of the digestive tract.
The European respiratory journal 2008;32(1):241-3.
2008: L Silvestri; H K F Van Saene; M A de la Cal; R E Sarginson
To review or not to review: that is the question.
The Journal of hospital infection 2008;69(2):189-90; author reply 190-1.
2008: L Silvestri; H K F Van Saene; A Casarin; G Berlot; A Gullo
Impact of selective decontamination of the digestive tract on carriage and infection due to Gram-negative and Gram-positive bacteria: a systematic review of randomised controlled trials.
Anaesthesia and intensive care 2008;36(3):324-38.
2008: H K F Van Saene; N Taylor; V Damjanovic; R E Sarginson
Microbial gut overgrowth guarantees increased spontaneous mutation leading to polyclonality and antibiotic resistance in the critically ill.
Current drug targets 2008;9(5):419-21.
2007: H K F Van Saene; Joris van Saene; Luciano Silvestri; Miguel A de la Cal; Richard Sarginson; Durk F Zandstra
Iseganan failure due to the wrong pharmaceutical technology.
Chest 2007;132(4):1412.
2007: Luciano Silvestri; Joris J M van Saene; H K F Van Saene; Ian Weir
Topical chlorhexidine and ventilator-associated pneumonia.
Critical care medicine 2007;35(10):2468.
2007: Nitin Verma; Ray W Clarke; Paula H B Bolton-Maggs; H K F Van Saene
Gut overgrowth of vancomycin-resistant enterococci (VRE) results in linezolid-resistant mutation in a child with severe congenital neutropenia: a case report.
Journal of pediatric hematology/oncology 2007;29(8):557-60.
2007: F Abecasis; S Kerr; Richard Sarginson; L Silvestri; Miguel A de la Cal; Durk F Zandstra; albertus beishuizen; Vladimir Damjanovic; H K F Van Saene
Comment on: emergence of multidrug-resistant Gram-negative bacteria during selective decontamination of the digestive tract on an intensive care unit.
The Journal of antimicrobial chemotherapy 2007;60(2):445; author reply 446.
2007: L Silvestri; H K F Van Saene; C Thomann; M Perić
Selective decontamination of the digestive tract reduces pneumonia and mortality without resistance emerging.
American journal of infection control 2007;35(5):354-7.
2007: Luciano Silvestri; H K F Van Saene; Richard Sarginson; Antonino Gullo
Selective decontamination of the digestive tract and ventilator-associated pneumonia: we cannot let misinformation go uncorrected.
Journal of intensive care medicine 2007;22(3):181-2; author reply 183.
2007: N Taylor; H K F Van Saene; A Abella; L Silvestri; M Vucic; M Peric
[Selective digestive decontamination. Why don't we apply the evidence in the clinical practice?].
Medicina intensiva / Sociedad Española de Medicina Intensiva y Unidades Coronarias 2007;31(3):136-45.
2007: Luciano Silvestri; H K F Van Saene; Antonino Gullo; Miguel A de la Cal
Guidelines for prevention, diagnosis, and treatment of ventilator-associated pneumonia (VAP) in the trauma patient.
The Journal of trauma 2007;62(4):1062-4; author reply 1064-5.
2007: Enrique Cerdá; Ana Abella; Miguel A de la Cal; José A Lorente; Paloma García Hierro; H K F Van Saene; Inmaculada Alía; Ainhoa Aranguren
Enteral vancomycin controls methicillin-resistant Staphylococcus aureus endemicity in an intensive care burn unit: a 9-year prospective study.
Annals of surgery 2007;245(3):397-407.
2007: L Silvestri; H K F Van Saene; M Milanese; Dario Gregori; Antonino Gullo
Selective decontamination of the digestive tract reduces bacterial bloodstream infection and mortality in critically ill patients. Systematic review of randomized, controlled trials.
The Journal of hospital infection 2007;65(3):187-203.
2007: Kentigern Thorburn; H K F Van Saene
Pulmonary bacterial co-infection in children ventilated for severe respiratory syncytial virus bronchiolitis is common.
Intensive care medicine 2007;33(3):565.
2007: CP Stoutenbeek; H K F Van Saene; R A Little; A Whitehead
The effect of selective decontamination of the digestive tract on mortality in multiple trauma patients: a multicenter randomized controlled trial.
Intensive care medicine 2007;33(2):261-70.
2006: Vladimir Damjanovic; H K F Van Saene
Polyclonal outbreaks: a story not yet told.
The Journal of hospital infection 2006;64(4):408-9.
2006: Luciano Silvestri; H K F Van Saene
Selective decontamination of the digestive tract does not increase resistance in critically ill patients: evidence from randomized controlled trials.
Critical care medicine 2006;34(7):2027-9; author reply 2029-30.
2006: Kentigern Thorburn; S Harigopal; V Reddy; Nia Taylor; H K F Van Saene
High incidence of pulmonary bacterial co-infection in children with severe respiratory syncytial virus (RSV) bronchiolitis.
Thorax 2006;61(7):611-5.
2006: H K F Van Saene; L Silvestri; Miguel A de la Cal; Richard Sarginson
Selective decontamination of the digestive tract reduces lower airway and bloodstream infection and mortality and prevents emergence of antimicrobial resistance.
Microbes and infection / Institut Pasteur 2006;8(3):953-4.
2006: Kentigern Thorburn; Nia Taylor; S M Saladi; H K F Van Saene
Use of surveillance cultures and enteral vancomycin to control methicillin-resistant Staphylococcus aureus in a paediatric intensive care unit.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2006;12(1):35-42.
2006: H K F Van Saene; Vladimir Damjanovic; Luciano Silvestri; Miguel A de la Cal; Durk F Zandstra
Selective decontamination of the digestive tract and ventilator-associated pneumonia (part 2).
Respiratory care 2006;51(1):72-5; author reply 75.
2006: Luciano Silvestri; Andy J Petros; Marino Viviani; Johannes H Rommes; H K F Van Saene
Selective decontamination of the digestive tract and ventilator-associated pneumonia (part 1).
Respiratory care 2006;51(1):67-9; author reply 70-2.
2006: Luciano Silvestri; H K F Van Saene; Miguel A de la Cal; Antonino Gullo
Adult hospital and ventilator-associated pneumonia guidelines: eminence- rather than evidence-based.
American journal of respiratory and critical care medicine 2006;173(1):131-3; author reply 133.
2005: Kentigern Thorburn; Nia Taylor; Lucia Lopez-Rodriguez; Michael Ashworth; Miguel A de la Cal; H K F Van Saene
High mortality of invasive pneumococcal disease compared with meningococcal disease in critically ill children.
Intensive care medicine 2005;31(11):1550-7.
2005: S C Paulus; H K F Van Saene; S Hemsworth; J Hughes; A Ng; Barry Pizer
A prospective study of septicaemia on a paediatric oncology unit: a three-year experience at The Royal Liverpool Children's Hospital, Alder Hey, UK.
European journal of cancer (Oxford, England : 1990) 2005;41(14):2132-40.
2005: Luciano Silvestri; H K F Van Saene; Marco Milanese; Dario Gregori
Impact of selective decontamination of the digestive tract on fungal carriage and infection: systematic review of randomized controlled trials.
Intensive care medicine 2005;31(7):898-910.
2005: Mark A Fox; Richard Sarginson; Durk F Zandstra; Iwan A Meynaar; H K F Van Saene
Comment on "risk factors for late-onset ventilator-associated pneumonia in trauma patients receiving selective digestive decontamination" by Leone et al.
Intensive care medicine 2005;31(7):999; author reply 1000.
2005: Marino Viviani; H K F Van Saene; R Dezzoni; L Silvestri; Roberto Di Lenarda; Giorgio Berlot; Antonino Gullo
Control of imported and acquired methicillin-resistant Staphylococcus aureus (MRSA) in mechanically ventilated patients: a dose-response study of enteral vancomycin to reduce absolute carriage and infection.
Anaesthesia and intensive care 2005;33(3):361-72.
2005: Juranko Kolak; H K F Van Saene; Miguel A de la Cal; Luciano Silvestre; Mladen Peric
Control of bacterial pneumonia during mechanical ventilation.
Croatian medical journal 2005;46(2):183-96.
2005: H K F Van Saene; L Silvestri; Miguel A de la Cal
Impact of nutrition route on fungal infections.
Clinical nutrition (Edinburgh, Scotland) 2005;24(2):326-7; author reply 328-9.
2005: Vladimir Damjanovic; H K F Van Saene
Microbial mutation as a source of polyclonality in the gut of the critically ill.
The Journal of hospital infection 2005;59(4):374-5.
2005: Miguel A de la Cal; Enrique Cerdá; Paloma García Hierro; H K F Van Saene; Dulce Gómez-Santos; Eva Negro; José A Lorente
Survival benefit in critically ill burned patients receiving selective decontamination of the digestive tract: a randomized, placebo-controlled, double-blind trial.
Annals of surgery 2005;241(3):424-30.
2005: L Silvestri; Andy J Petros; Richard Sarginson; Miguel A de la Cal; A E Murray; H K F Van Saene
Handwashing in the intensive care unit: a big measure with modest effects.
The Journal of hospital infection 2005;59(3):172-9.
2005: Marino Viviani; Luciano Silvestri; H K F Van Saene; Antonino Gullo
Surviving Sepsis Campaign Guidelines: selective decontamination of the digestive tract still neglected.
Critical care medicine 2005;33(2):462-3; author reply 463-4.
2004: Paul Baines; H K F Van Saene
Selective decontamination of the digestive tract and prevention of ventilator-associated pneumonia.
Annals of internal medicine 2004;141(7):577; author reply 577-8.
2004: H K F Van Saene; M Ashworth; A J Petros; M Sanchez; Miguel A de la Cal
Do not suction above the cuff.
Critical care medicine 2004;32(10):2160-2.
2004: H K F Van Saene; Durk F Zandstra
Selective decontamination of the digestive tract: rationale behind evidence-based use in liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2004;10(7):828-33.
2004: Kentigern Thorburn; S Kerr; Nia Taylor; H K F Van Saene
RSV outbreak in a paediatric intensive care unit.
The Journal of hospital infection 2004;57(3):194-201.
2004: L Silvestri; H K F Van Saene; M Milanese; F Fontana; Dario Gregori; L Oblach; N Piacente; M Blazic
Prevention of MRSA pneumonia by oral vancomycin decontamination: a randomised trial.
The European respiratory journal 2004;23(6):921-6.
2004: Viviane M Conraads; Philippe G Jorens; Luc S De Clerck; H K F Van Saene; Margareta Ieven; Johan M Bosmans; Annemie J Schuerwegh; Chris H Bridts; Floris L Wuyts; Wim J Stevens; Stefan D Anker; Mathias Rauchhaus; Christiaan Vrints
Selective intestinal decontamination in advanced chronic heart failure: a pilot trial.
European journal of heart failure 2004;6(4):483-91.
2004: Richard Sarginson; N Taylor; N Reilly; Paul Baines; H K F Van Saene
Infection in prolonged pediatric critical illness: A prospective four-year study based on knowledge of the carrier state.
Critical care medicine 2004;32(3):839-47.
2004: H K F Van Saene; W I Weir; Miguel A de la Cal; L Silvestri; Andy J Petros; S P Barrett
MRSA--time for a more pragmatic approach?
The Journal of hospital infection 2004;56(3):170-4.
2004: Stephen C Donnell; N Taylor; H K F Van Saene
Translocation cannot be ignored during parenteral nutrition.
The Journal of hospital infection 2004;56(3):246-7.
2004: Miguel A de la Cal; Enrique Cerdá; H K F Van Saene; Paloma García Hierro; E Negro; M L Parra; S Arias; D Ballesteros
Effectiveness and safety of enteral vancomycin to control endemicity of methicillin-resistant Staphylococcus aureus in a medical/surgical intensive care unit.
The Journal of hospital infection 2004;56(3):175-83.
2004: Vladimir Damjanovic; H K F Van Saene
Polyclonal outbreaks-more common than you expect.
The Journal of hospital infection 2004;56(1):76-7.
2003: A Solís; D Brown; J Hughes; H K F Van Saene; D P Heaf
Methicillin-resistant Staphylococcus aureus in children with cystic fibrosis: An eradication protocol.
Pediatric pulmonology 2003;36(3):189-95.
2003: H K F Van Saene; L Silvestri; Andy J Petros; Marino Viviani; Miguel A de la Cal; Durk F Zandstra
Comment on "Prevention of severe Candida infections in non-neutropenic, high-risk, critically ill patients," by Garbino et al.
Intensive care medicine 2003;29(7):1192-3; author reply 1194-5.
2003: H K F Van Saene; L Silvestri; J L Bams; Peter H J van der Voort; Durk F Zandstra
Selective decontamination of the digestive tract: use in liver transplantation is evidence based.
Critical care medicine 2003;31(5):1600-1.
2003: H K F Van Saene; Andy J Petros; Graham Ramsay; Derrick Baxby
All great truths are iconoclastic: selective decontamination of the digestive tract moves from heresy to level 1 truth.
Intensive care medicine 2003;29(5):677-90.
2003: H K F Van Saene; N Taylor; Stephen C Donnell; J Glynn; V L Magnall; Y Okada; N J Klein; Agostino Pierro; David A Lloyd
Gut overgrowth with abnormal flora: the missing link in parenteral nutrition-related sepsis in surgical neonates.
European journal of clinical nutrition 2003;57(4):548-53.
2003: Heleen Oudemans-van Straaten; H K F Van Saene; Durk F Zandstra
Selective decontamination of the digestive tract: use of the correct antibiotics is crucial.
Critical care medicine 2003;31(1):334-5.
2002: Stephen C Donnell; N Taylor; H K F Van Saene; V L Magnall; Agostino Pierro; David A Lloyd
Infection rates in surgical neonates and infants receiving parenteral nutrition: a five-year prospective study.
The Journal of hospital infection 2002;52(4):273-80.
2002: Luciano Silvestri; Marco Milanese; Luisa Oblach; Francesco Fontana; Dario Gregori; Romano Guerra; H K F Van Saene
Enteral vancomycin to control methicillin-resistant Staphylococcus aureus outbreak in mechanically ventilated patients.
American journal of infection control 2002;30(7):391-9.
2002: L Silvestri; Richard Sarginson; Julie Hughes; M Milanese; Dario Gregori; H K F Van Saene
Most nosocomial pneumonias are not due to nosocomial bacteria in ventilated patients. Evaluation of the accuracy of the 48 h time cut-off using carriage as the gold standard.
Anaesthesia and intensive care 2002;30(3):275-82.
2001: Paul Baines; N Reilly; H K F Van Saene
Control of resistance to sulphonamides.
Lancet 2001;358(9283):761.
2001: L Silvestri; F Mannucci; H K F Van Saene
Selective decontamination of the digestive tract.
The Journal of hospital infection 2001;48(4):322-4.
2001: D F Zandstra; H K F Van Saene
Selective decontamination of the digestive tract as infection prevention in the critically ill. Does it lead to resistance?
Minerva anestesiologica 2001;67(4):292-7.
2001: Miguel A de la Cal; Enrique Cerdá; Paloma García Hierro; L Lorente; M Sánchez-Concheiro; C Díaz; H K F Van Saene
Pneumonia in patients with severe burns : a classification according to the concept of the carrier state.
Chest 2001;119(4):1160-5.
2001: Andy J Petros; M O'Connell; C Roberts; P Wade; H K F Van Saene
Systemic antibiotics fail to clear multidrug-resistant Klebsiella from a pediatric ICU.
Chest 2001;119(3):862-6.
2001: KR Shankar; D Brown; J Hughes; Graham L Lamont; Paul D Losty; David A Lloyd; H K F Van Saene
Classification and risk-factor analysis of infections in a surgical neonatal unit.
Journal of pediatric surgery 2001;36(2):276-81.
2000: L Silvestri; F Mannucci; H K F Van Saene
Selective decontamination of the digestive tract: a life saver.
The Journal of hospital infection 2000;45(3):185-90.
2000: H K F Van Saene; Miguel A de la Cal; A J Petros
Semirecumbent position in intensive care patients.
Lancet 2000;355(9208):1012-3.
2000: H K F Van Saene
To suction or not to suction, above the cuff.
Critical care medicine 2000;28(2):596-8.
2000: Y Okada; Nigel J Klein; H K F Van Saene; G Webb; H Holzel; Agostino Pierro
Bactericidal activity against coagulase-negative staphylococci is impaired in infants receiving long-term parenteral nutrition.
Annals of surgery 2000;231(2):276-81.
2000: H F McAndrew; D A Lloyd; R Rintala; H K F Van Saene
The effects of intravenous epidermal growth factor on bacterial translocation and central venous catheter infection in the rat total parenteral nutrition model.
Pediatric surgery international 2000;16(3):169-73.
1999: KJ Mobbs; H K F Van Saene; D Sunderland; P D Davies
Oropharyngeal gram-negative bacillary carriage in chronic obstructive pulmonary disease: relation to severity of disease.
Respiratory medicine 1999;93(8):540-5.
1999: H K F Van Saene; Paul Baines
The prevention of ventilator-associated pneumonia.
The New England journal of medicine 1999;341(4):293-4.
1999: L Silvestri; C Monti Bragadin; M Milanese; Dario Gregori; C Consales; Antonino Gullo; H K F Van Saene
Are most ICU infections really nosocomial? A prospective observational cohort study in mechanically ventilated patients.
The Journal of hospital infection 1999;42(2):125-33.
1999: KJ Mobbs; H K F Van Saene; D Sunderland; P D Davies
Oropharyngeal Gram-negative bacillary carriage: a survey of 120 healthy individuals.
Chest 1999;115(6):1570-5.
1999: H K F Van Saene; Vladimir Damjanovic; Barry Pizer; A J Petros
Fungal infections in ICU.
The Journal of hospital infection 1999;41(4):337-40.
1999: Johannes H Rommes; D F Zandstra; H K F Van Saene
[Selective decontamination of the digestive tract reduces mortality in intensive care patients].
Nederlands tijdschrift voor geneeskunde 1999;143(12):602-6.
1999: H F McAndrew; D A Lloyd; R Rintala; H K F Van Saene
Intravenous glutamine or short-chain fatty acids reduce central venous catheter infection in a model of total parenteral nutrition.
Journal of pediatric surgery 1999;34(2):281-5.
1998: Stephen C Donnell; N Taylor; H K F Van Saene; Agostino Pierro; David A Lloyd
Nutritional implications of gut overgrowth and selective decontamination of the digestive tract.
The Proceedings of the Nutrition Society 1998;57(3):381-7.
1998: Agostino Pierro; H K F Van Saene; Matthew O Jones; D Brown; A J Nunn; David A Lloyd
Clinical impact of abnormal gut flora in infants receiving parenteral nutrition.
Annals of surgery 1998;227(4):547-52.
1998: H K F Van Saene; Vladimir Damjanovic; T Williets; S M Mostafa; M A Fox; A J Petros
Pathogenesis of ventilator-associated pneumonia: is the contribution of biofilm clinically significant?
The Journal of hospital infection 1998;38(3):231-5.
1998: H K F Van Saene; CP Stoutenbeek; Durk F Zandstra
Selective decontamination of the digestive tract (SDD) in multiple trauma patients.
The Journal of trauma 1998;44(3):570-2.
1998: Y Okada; N Klein; H K F Van Saene; A Pierro
Small volumes of enteral feedings normalise immune function in infants receiving parenteral nutrition.
Journal of pediatric surgery 1998;33(1):16-9.
1997: CP Stoutenbeek; H K F Van Saene
Nonantibiotic measures in the prevention of ventilator-associated pneumonia.
Seminars in respiratory infections 1997;12(4):294-9.
1997: Vladimir Damjanovic; H K F Van Saene
Outbreaks of infection in neonatal intensive care units (NICU)
The Journal of hospital infection 1997;35(3):237-44.
1996: T S Leenstra; J J van Saene; H K F Van Saene; M V Martin
Oral endotoxin in healthy adults.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 1996;82(6):637-43.
1996: K Cheng; Rosalind Smyth; John R W Govan; C Doherty; Craig Winstanley; N Denning; D P Heaf; H K F Van Saene; C Anthony Hart
Spread of beta-lactam-resistant Pseudomonas aeruginosa in a cystic fibrosis clinic.
Lancet 1996;348(9028):639-42.
1996: D Baxby; H K F Van Saene; C P Stoutenbeek; Durk F Zandstra
Selective decontamination of the digestive tract: 13 years on, what it is and what it is not.
Intensive care medicine 1996;22(7):699-706.
1996: V Damjanovic; H K F Van Saene
Coagulase-negative staphylococci (CNS) and necrotizing enterocolitis (NEC)
The Journal of hospital infection 1996;33(2):153-5.
1996: H K F Van Saene; V Damjanovic; A E Murray; M A de la Cal
How to classify infections in intensive care units--the carrier state, a criterion whose time has come?
The Journal of hospital infection 1996;33(1):1-12.
1996: Agostino Pierro; H K F Van Saene; S C Donnell; J Hughes; C Ewan; A J Nunn; David A Lloyd
Microbial translocation in neonates and infants receiving long-term parenteral nutrition.
Archives of surgery (Chicago, Ill. : 1960) 1996;131(2):176-9.
1995: H K F Van Saene; A J Nunn; C P Stoutenbeek
Selective decontamination of the digestive tract in intensive care patients.
British journal of hospital medicine 1995;54(11):558-61.
1995: V Damjanovic; H K F Van Saene; C Anthony Hart
Surveillance cultures on neonatal intensive care units.
The Journal of hospital infection 1995;31(1):73-5.
1995: H K F Van Saene; M A Fox; C P Stoutenbeek
Treating selective decontamination of the digestive tract vs cost-effectiveness analysis.
Chest 1995;108(1):288.
1995: V Damjanovic; H K F Van Saene
Coagulase-negative staphylococcal sepsis in preterm neonates.
Lancet 1995;346(8966):51.
1995: H K F Van Saene; C P Stoutenbeek; J C Marshall
Selective digestive decontamination in critically ill patients.
Critical care medicine 1995;23(3):601-2.
1995: Simon Kenny; Agostino Pierro; D Isherwood; S C Donnell; H K F Van Saene; David A Lloyd
Hypoalbuminaemia in surgical neonates receiving parenteral nutrition.
Journal of pediatric surgery 1995;30(3):454-7.
1995: H K F Van Saene; D F Zandstra
[Selective decontamination of the digestive tract in patients with artificial respiration in an intensive care unit: more arguments for than against].
Nederlands tijdschrift voor geneeskunde 1995;139(1):42-3.
1994: V Damjanovic; H K F Van Saene; A M Weindling; R W Cook; C Anthony Hart
The multiple value of surveillance cultures: an alternative view.
The Journal of hospital infection 1994;28(1):71-5.
1994: C P Stoutenbeek; H K F Van Saene
[The intestine as a central organ in infection].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 1994;29(5):259-63.
1994: H K F Van Saene; A J Nunn; A J Petros
Viewpoint: survival benefit by selective decontamination of the digestive tract (SDD).
Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 1994;15(7):443-6.
1994: H K F Van Saene; S R Alcock; J H Rommes; D Baxby; A Percival
Impact of SDD on ICU ecology.
Intensive care medicine 1994;20(6):459-60.
1994: C J Rogers; H K F Van Saene; P M Suter; R Horner; M L Orme
Infection control in critically ill patients: effects of selective decontamination of the digestive tract.
American journal of hospital pharmacy 1994;51(5):631-48; quiz 698-9.
1993: V Damjanovic; H K F Van Saene; R W Cooke; A Pierro
Oral vancomycin in staphylococcal septicaemia of bowel origin in neonates.
The Journal of hospital infection 1993;25(3):215-8.
1993: V Damjanovic; C M Connolly; H K F Van Saene; R W Cooke; J E Corkill; Alex Van Belkum; D van Velzen
Selective decontamination with nystatin for control of a Candida outbreak in a neonatal intensive care unit.
The Journal of hospital infection 1993;24(4):245-59.
1993: H K F Van Saene; K E Unertl; S R Alcock; C P Stoutenbeek; C Anthony Hart
Emergence of antibiotic resistance during selective digestive decontamination?
The Journal of hospital infection 1993;24(2):158-61.
1993: H K F Van Saene; A Percival; C A Hart; A Liberati; C P Stoutenbeek
Selective decontamination of the gut.
BMJ (Clinical research ed.) 1993;306(6884):1064.
1993: L E Rhodes; H K F Van Saene; S White; S Fairclough; L M Ball; J Martin
Microbial carriage, sepsis, infection and acute GVHD in the first 25 BMT at the Royal Liverpool Children's Hospital.
Bone marrow transplantation 1993;11(4):261-9.
1992: P McClelland; A Murray; M Yaqoob; H K F Van Saene; J M Bone; S M Mostafa
Prevention of bacterial infection and sepsis in acute severe pancreatitis.
Annals of the Royal College of Surgeons of England 1992;74(5):329-34.
1992: A Kaufhold; W Behrendt; T Kräuss; H K F Van Saene
Selective decontamination of the digestive tract and methicillin-resistant Staphylococcus aureus.
Lancet 1992;339(8806):1411-2.
1992: H K F Van Saene; C P Stoutenbeek; A Torres
The abnormal oropharyngeal carrier state: symptom or disease?
Respiratory medicine 1992;86(3):183-6.
1992: H K F Van Saene; C C Stoutenbeek; J K Stoller
Selective decontamination of the digestive tract in the intensive care unit: current status and future prospects.
Critical care medicine 1992;20(5):691-703.
1992: C P Stoutenbeek; H K F Van Saene
Prevention of pneumonia by selective decontamination of the digestive tract (SDD).
Intensive care medicine 1992;18 Suppl 1():S18-23.
1991: M A Fox; S Peterson; B M Fabri; H K F Van Saene
Selective decontamination of the digestive tract in cardiac surgical patients.
Critical care medicine 1991;19(12):1486-90.
1991: H K F Van Saene; A Percival
Bowel microorganisms--a target for selective antimicrobial control.
The Journal of hospital infection 1991;19 Suppl C():19-41.
1991: H K F Van Saene; C P Stoutenbeek; C Anthony Hart
Selective decontamination of the digestive tract (SDD) in intensive care patients: a critical evaluation of the clinical, bacteriological and epidemiological benefits.
The Journal of hospital infection 1991;18(4):261-77.
1991: P H Bolton-Maggs; H K F Van Saene; H P McDowell; J Martin
Clinical evaluation of ticarcillin, with clavulanic acid, and gentamicin in the treatment of febrile episodes in neutropenic children.
The Journal of antimicrobial chemotherapy 1991;27(5):669-76.
1990: A M Dalzell; H K F Van Saene; D P Heaf
Cystic fibrosis, Pseudomonas aeruginosa, and selective decontamination.
Archives of disease in childhood 1990;65(12):1365-7.
1990: H K F Van Saene; M V Martin
Do microorganisms play a role in irradiation mucositis?
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1990;9(12):861-3.
1990: P McClelland; A E Murray; P S Williams; H K F Van Saene; A A Gilbertson; S M Mostafa; J Michael Bone
Reducing sepsis in severe combined acute renal and respiratory failure by selective decontamination of the digestive tract.
Critical care medicine 1990;18(9):935-9.
1990: V Damjanovic; T H Williets; D Glynne-Thomas; H K F Van Saene
Eradication of Salmonella by oral ciprofloxacin in food handlers.
Lancet 1990;335(8695):974.
1990: E M Leonard; H K F Van Saene; P Shears; J Walker; P K Tam
Pathogenesis of colonization and infection in a neonatal surgical unit.
Critical care medicine 1990;18(3):264-9.
1990: E J Vollaard; H A Clasener; H K F Van Saene; N F Muller
Effect on colonization resistance: an important criterion in selecting antibiotics.
DICP : the annals of pharmacotherapy 1990;24(1):60-6.
1990: H K F Van Saene; C P Stoutenbeek; A A Gilbertson
Review of available trials of selective decontamination of the digestive tract (SDD).
Infection 1990;18 Suppl 1():S5-9.
1990: A M Dalzell; H K F Van Saene; D P Heaf
Selective oral decontamination in cystic fibrosis: an attempt to prevent pseudomonas colonisation.
Acta Universitatis Carolinae. Medica 1990;36(1-4):40-1.
1990: C P Stoutenbeek; H K F Van Saene
How to improve infection prevention by selective decontamination of the digestive tract (SDD).
Infection 1990;18 Suppl 1():S10-3.
1990: H K F Van Saene; C P Stoutenbeek
Oropharyngeal and gastrointestinal carriage in the critically ill.
Agressologie: revue internationale de physio-biologie et de pharmacologie appliquées aux effets de l'agression 1990;31(8 Spec No):557-9.
1989: C P Stoutenbeek; H K F Van Saene; C Krier
[Selective decontamination of the intestine--a principle of infection prevention on its way to becoming an established method?].
Anästhesie, Intensivtherapie, Notfallmedizin 1989;24(6):321-2.
1989: H K F Van Saene; J C Van Putte; J J Van Saene; T W Van de Gronde; E G Van Warmerdam
Sink flora in a long-stay hospital is determined by the patients' oral and rectal flora.
Epidemiology and infection 1989;102(2):231-8.
1988: H K F Van Saene; S E Lemmens; J J van Saene
Gut decontamination by oral ofloxacin and ciprofloxacin in healthy volunteers.
The Journal of antimicrobial chemotherapy 1988;22 Suppl C():127-34.
1988: H K F Van Saene; C P Stoutenbeek; Durk F Zandstra
Cefotaxime combined with selective decontamination in long term intensive care unit patients. Virtual absence of emergence of resistance.
Drugs 1988;35 Suppl 2():29-34.
1988: Durk F Zandstra; C P Stoutenbeek; H K F Van Saene; J L Bams
Selective decontamination of the digestive tract improves survival in patients receiving differential lung ventilation.
Intensive care medicine 1988;15(1):15-8.
1987: H K F Van Saene; C P Stoutenbeek
Selective decontamination.
The Journal of antimicrobial chemotherapy 1987;20(4):462-5.
1987: C P Stoutenbeek; H K F Van Saene; Durk F Zandstra
The effect of oral non-absorbable antibiotics on the emergence of resistant bacteria in patients in an intensive care unit.
The Journal of antimicrobial chemotherapy 1987;19(4):513-20.
1987: C P Stoutenbeek; H K F Van Saene; D R Miranda; Durk F Zandstra; D Langrehr
The effect of oropharyngeal decontamination using topical nonabsorbable antibiotics on the incidence of nosocomial respiratory tract infections in multiple trauma patients.
The Journal of trauma 1987;27(4):357-64.
1987: H A Clasener; E J Vollaard; H K F Van Saene
Long-term prophylaxis of infection by selective decontamination in leukopenia and in mechanical ventilation.
Reviews of infectious diseases 1987;9(2):295-328.
1987: R van Uffelen; J H Rommes; H K F Van Saene
Preventing lower airway colonization and infection in mechanically ventilated patients.
Critical care medicine 1987;15(2):99-102.
1987: H K F Van Saene; C P Stoutenbeek; Durk F Zandstra; A A Gilbertston; A Murray; C Anthony Hart
Nosocomial infections in severely traumatized patients: magnitude of problem, pathogenesis, prevention and therapy.
Acta anaesthesiologica Belgica 1987;38(4):347-53.
1986: H K F Van Saene; C P Stoutenbeek; D R Miranda; Durk F Zandstra; D Langrehr
Recent advances in the control of infection in patients with thoracic injury.
Injury 1986;17(5):332-5.
1986: H K F Van Saene; C P Stoutenbeek
[Airway infections in patients in intensive care units; pathogenesis and prevention].
Nederlands tijdschrift voor geneeskunde 1986;130(28):1291.
1986: J J Van Saene; H K F Van Saene; J N Geitz; N J Tarko-Smit; C F Lerk
Quinolones and colonization resistance in human volunteers.
Pharmaceutisch weekblad. Scientific edition 1986;8(1):67-71.
1986: C P Stoutenbeek; H K F Van Saene; D R Miranda; Durk F Zandstra; D Langrehr
Nosocomial gram-negative pneumonia in critically ill patients. A 3-year experience with a novel therapeutic regimen.
Intensive care medicine 1986;12(6):419-23.
1984: C P Stoutenbeek; H K F Van Saene; D R Miranda; Durk F Zandstra; B Binnendijk
The prevention of superinfection in multiple trauma patients.
The Journal of antimicrobial chemotherapy 1984;14 Suppl B():203-11.
1984: R van Uffelen; H K F Van Saene; Vaclav Fidler; A Löwenberg
Oropharyngeal flora as a source of bacteria colonizing the lower airways in patients on artificial ventilation.
Intensive care medicine 1984;10(5):233-7.
1984: C P Stoutenbeek; H K F Van Saene; D R Miranda; Durk F Zandstra
The effect of selective decontamination of the digestive tract on colonisation and infection rate in multiple trauma patients.
Intensive care medicine 1984;10(4):185-92.
1984: D F Vieira; H K F Van Saene; D R Miranda
Invasive pulmonary aspergillosis after near-drowning.
Intensive care medicine 1984;10(4):203-4.
1983: D R Miranda; H K F Van Saene; C P Stoutenbeek; Durk F Zandstra
Environment and costs in surgical intensive care unit. The implication of selective decontamination of the digestive tract (SDD).
Acta anaesthesiologica Belgica 1983;34(3):223-32.
1983: H K F Van Saene; C P Stoutenbeek; D R Miranda; Durk F Zandstra
A novel approach to infection control in the intensive care unit.
Acta anaesthesiologica Belgica 1983;34(3):193-208.
1983: C P Stoutenbeek; H K F Van Saene; D R Miranda; Durk F Zandstra
A new technique of infection prevention in the intensive care unit by selective decontamination of the digestive tract.
Acta anaesthesiologica Belgica 1983;34(3):209-21.
1983: C P Stoutenbeek; H K F Van Saene; D R Miranda; D van der Waaij
Acinetobacter mediastinitis and pneumonia in a thorotrastoma patient. The oropharyngeal flora as source of infection.
Intensive care medicine 1983;9(3):139-41.
1982: H G de Vries-Hospers; N H Mulder; D T Sleijfer; H K F Van Saene
The effect of amphotericin B lozenges on the presence and number of Candida cells in the oropharynx of neutropenic leukemia patients.
Infection 1982;10(2):71-5.
1981: H G de Vries-Hospers; D T Sleijfer; N H Mulder; D van der Waaij; H O Neiweg; H K F Van Saene
Bacteriological aspects of selective decontamination of the digestive tract as a method of infection prevention in granulocytopenic patients.
Antimicrobial agents and chemotherapy 1981;19(5):813-20.
1979: H K F Van Saene; D Van der Waaij
A novel technique for detecting IgA coated potentially pathogenic microorganisms in the human intestine.
Journal of immunological methods 1979;30(1):87-96.
1979: H K F Van Saene; J P Nicolai
The prevention of wound infections in burn patients.
Scandinavian journal of plastic and reconstructive surgery 1979;13(1):63-7.