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Tibor van Welsem

Research Profile

Chemicals & Drugs

Anatomy

Genes & Molecular Sequences

BRCA1 Genes

Living Beings

Saccharomyces cerevisiae

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Disorders

Breast Neoplasms

Physiology

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Publications

TOP 3
Joke G van Bemmel; F van Leeuwen; Tibor van Welsem; Marcel de Haas; Guillaume J Filion; Arantxa Rosado; Wendy Talhout; Bas van Steensel
A network model of the molecular organization of chromatin in Drosophila.
Marta Radman-Livaja; Oliver J Rando; Lourdes Valenzuela; F van Leeuwen; Tibor van Welsem; Jennifer A Armstrong; Stephen Buratowski; Taesoo Kim; Laura J Lee; Tiffani K Quan; Grant A Hartzog
A key role for Chd1 in histone H3 dynamics at the 3' ends of long genes in yeast.
Kitty F Verzijlbergen; Tibor van Welsem; Frank C P Holstege; Ron Kerkhoven; Tineke L Lenstra; Daoud Sie; Daniel J Turner; F van Leeuwen
A barcode screen for epigenetic regulators reveals a role for the NuB4/HAT-B histone acetyltransferase complex in histone turnover.

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All Publications

2013: Joke G van Bemmel; F van Leeuwen; Tibor van Welsem; Marcel de Haas; Guillaume J Filion; Arantxa Rosado; Wendy Talhout; Bas van Steensel
A network model of the molecular organization of chromatin in Drosophila.
Molecular cell 2013;49(4):759-71.
2012: Marta Radman-Livaja; Oliver J Rando; Lourdes Valenzuela; F van Leeuwen; Tibor van Welsem; Jennifer A Armstrong; Stephen Buratowski; Taesoo Kim; Laura J Lee; Tiffani K Quan; Grant A Hartzog
A key role for Chd1 in histone H3 dynamics at the 3' ends of long genes in yeast.
PLoS genetics 2012;8(7):e1002811.
2011: Kitty F Verzijlbergen; Tibor van Welsem; Frank C P Holstege; Ron Kerkhoven; Tineke L Lenstra; Daoud Sie; Daniel J Turner; F van Leeuwen
A barcode screen for epigenetic regulators reveals a role for the NuB4/HAT-B histone acetyltransferase complex in histone turnover.
PLoS genetics 2011;7(10):e1002284.
2011: Dirk De Vos; Floor Frederiks; Albert J R Heck; Ekaterina Iachina; Jeroen Krijgsveld; Gideon Oudgenoeg; Marit Terweij; Barbara M Bakker; Erik L de Graaf; Tibor van Welsem; Kitty F Verzijlbergen; A F Maarten Altelaar; Fred van Leeuwen
Progressive methylation of ageing histones by Dot1 functions as a timer.
EMBO reports 2011;12(9):956-62.
2011: Marta Radman-Livaja; Oliver J Rando; Tibor van Welsem; Kitty F Verzijlbergen; Assaf Weiner; Nir Friedman; Fred van Leeuwen
Patterns and mechanisms of ancestral histone protein inheritance in budding yeast.
PLoS biology 2011;9(6):e1001075.
2011: Iris Je Stulemeijer; Brietta L Pike; Alex W Faber; Kitty F Verzijlbergen; Tibor van Welsem; Floor Frederiks; Tineke L Lenstra; Frank Cp Holstege; Susan M Gasser; Fred van Leeuwen
Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms.
Epigenetics & chromatin 2011;4(1):2.
2010: Floor Frederiks; Tibor van Welsem; Gideon Oudgenoeg; Albert J R Heck; Christian J Janzen; F van Leeuwen
Heterologous expression reveals distinct enzymatic activities of two DOT1 histone methyltransferases of Trypanosoma brucei.
Journal of cell science 2010;123(Pt 23):4019-23.
2010: Kitty F Verzijlbergen; Victoria Menendez-Benito; Tibor van Welsem; Sjoerd J van Deventer; Derek L Lindstrom; Huib Ovaa; Jacques Neefjes; Daniel E Gottschling; F van Leeuwen
Recombination-induced tag exchange to track old and new proteins.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(1):64-8.
2008: Floor Frederiks; Manuel Tzouros; Gideon Oudgenoeg; Tibor van Welsem; Maarten Fornerod; Jeroen Krijgsveld; F van Leeuwen
Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states.
Nature structural & molecular biology 2008;15(6):550-7.
2008: Tibor van Welsem; Floor Frederiks; Kitty F Verzijlbergen; alex faber; Zara W Nelson; David A Egan; Daniel E Gottschling; F van Leeuwen
Synthetic lethal screens identify gene silencing processes in yeast and implicate the acetylated amino terminus of Sir3 in recognition of the nucleosome core.
Molecular and cellular biology 2008;28(11):3861-72.
2005: erik van beers; Tibor van Welsem; Lodewyk F A Wessels; Yunlei Li; Rogier A Oldenburg; Peter Devilee; Cees J Cornelisse; Senno Verhoef; Frans B L Hogervorst; Laura J van't Veer; petra nederlof
Comparative genomic hybridization profiles in human BRCA1 and BRCA2 breast tumors highlight differential sets of genomic aberrations.
Cancer research 2005;65(3):822-7.
2003: Frans B L Hogervorst; petra nederlof; Johan J P Gille; Cathal J McElgunn; Maartje Grippeling; Roelof Pruntel; Rein Regnerus; Tibor van Welsem; Rosalina Spaendonk; Fred H Menko; Irma Kluijt; Charlotte Dommering; Senno Verhoef; Jan P Schouten; Laura J van't Veer; Gerard Pals
Large genomic deletions and duplications in the BRCA1 gene identified by a novel quantitative method.
Cancer research 2003;63(7):1449-53.
2002: Lodewyk F A Wessels; Tibor van Welsem; Augustinus A M Hart; Laura J van't Veer; Marcel J T Reinders; petra nederlof
Molecular classification of breast carcinomas by comparative genomic hybridization: a specific somatic genetic profile for BRCA1 tumors.
Cancer research 2002;62(23):7110-7.
2000: Jacqueline J L Jacobs; P Keblusek; Els C Robanus-Maandag; Petra M P Kristel; Merel Lingbeek; petra nederlof; Tibor van Welsem; Marc J van de Vijver; Eugene Koh; George Q Daley; Maarten van Lohuizen
Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.
Nature genetics 2000;26(3):291-9.