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Pieter van Zwieten

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Co-Publications
Name
125
Pfaffendorf, Martin
24
Mathy, Marie-Jeanne
20
Chang, PC
18
Batink, HD
15
Balt, Jippe
15
Peters, Stephan
13
Blauw, Gerard
12
Doods, Henri
12
Nap, Alexander
7
Sand, Carsten
7
Streefkerk, Jörn
7
van Wezel, Harry
6
van Royen, EA
6
Somsen, Aernout
6
van der Lee, R

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Publications

TOP 3
de Groot Annemieke A; Mathy Marie-Jeanne; van Zwieten Pieter A; Peters Stephan L M
Vasodilator effects of nebivolol in a rat model of hypertension and a rabbit model of congestive heart failure.
Van Zwieten P A
Do we need new antihypertensive treatments?
Streefkerk J O; van Zwieten P A
Vasopressin receptor antagonists: pharmacological tools and potential therapeutic agents.

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All Publications

2007: de Groot Annemieke A; Mathy Marie-Jeanne; van Zwieten Pieter A; Peters Stephan L M
Vasodilator effects of nebivolol in a rat model of hypertension and a rabbit model of congestive heart failure.
Journal of cardiovascular pharmacology 2007;50(1):56-60.
2007: Van Zwieten P A
Do we need new antihypertensive treatments?
Blood pressure 2007;16(5):291-300.
2006: Streefkerk J O; van Zwieten P A
Vasopressin receptor antagonists: pharmacological tools and potential therapeutic agents.
Autonomic & autacoid pharmacology 2006;26(2):141-8.
2005: van Zwieten Peter A; Farsang Csaba
Combination of antihypertensive drugs from a historical perspective.
Blood pressure 2005;14(2):72-9.
2004: Nap Alexander; Mathy Marie-Jeanne; Balt Jippe C; Pfaffendorf Martin; van Zwieten Pieter A
The evaluation of the N-type channel blocking properties of cilnidipine and other voltage-dependent calcium antagonists.
Fundamental & clinical pharmacology 2004;18(3):309-19.
2004: Nap Alexander; Mathy Marie-Jeanne; Pfaffendorf Martin; van Zwieten Pieter A
Different prejunctional and postjunctional responses to angiotensin II and AT1-receptor inhibition: influence of maturation.
Journal of cardiovascular pharmacology 2004;43(3):432-9.
2004: Streefkerk Jörn O; Balt Jippe C; van Montfrans Gert A; van Lieshout Johan J; Pfaffendorf Martin; van Zwieten Pieter A
Vasopressin facilitates presynaptic sympathetic nerve activity in humans.
Journal of hypertension 2004;22(3):551-5.
2004: Streefkerk Jörn O; Hoogaars Willem M H; Christoffels Vincent M; Sand Carsten; Pfaffendorf Martin; Peters Stephan L M; Van Zwieten Pieter A
Vasopressin-induced vasoconstriction is dependent on MAPKerk1/2 phosphorylation.
Fundamental & clinical pharmacology 2004;18(1):45-50.
2004: de Groot Annemieke A; van Zwieten Pieter A; Peters Stephan L M
Involvement of reactive oxygen species in angiotensin II-induced vasoconstriction.
Journal of cardiovascular pharmacology 2004;43(1):154-9.
2004: de Groot Annemieke A; Mathy Marie-Jeanne; van Zwieten Pieter A; Peters Stephan L M
Antioxidant activity of nebivolol in the rat aorta.
Journal of cardiovascular pharmacology 2004;43(1):148-53.
2004: Nap Alexander; Balt Jippe C; Mathy Marie-Jeanne; Pfaffendorf Martin; van Zwieten Pieter A
Different AT1 receptor subtypes at pre- and postjunctional sites: AT1A versus AT1B receptors.
Journal of cardiovascular pharmacology 2004;43(1):14-20.
2003: Nap Alexander; Belterman Charly N W; Mathy Marie-Jeanne; Balt Jippe C; Pfaffendorf Martin; van Zwieten Pieter A
Impaired neuronal and vascular responses to angiotensin II in a rabbit congestive heart failure model.
Journal of the renin-angiotensin-aldosterone system : JRAAS 2003;4(4):220-7.
2003: Streefkerk Jörn O; Pfaffendorf Martin; van Zwieten Pieter A
Endothelium-dependent, vasopressin-induced contractions in rabbit renal arteries.
Journal of cardiovascular pharmacology 2003;42(6):703-9.
2003: Nap A; Balt J C; Mathy M J; Van Zwieten P A
AT(1)-receptor blockade and sympathetic neurotransmission in cardiovascular disease.
Autonomic & autacoid pharmacology 2003;23(5-6):285-96.
2003: de Groot Annemieke A; Mathy Marie-Jeanne; van Zwieten Pieter A; Peters Stephan L M
Involvement of the beta3 adrenoceptor in nebivolol-induced vasorelaxation in the rat aorta.
Journal of cardiovascular pharmacology 2003;42(2):232-6.
2003: Sand Carsten; Peters Stephan L M; Pfaffendorf Martin; van Zwieten Pieter A
The influence of endogenously generated reactive oxygen species on the inotropic and chronotropic effects of adrenoceptor and ET-receptor stimulation.
Naunyn-Schmiedeberg's archives of pharmacology 2003;367(6):635-9.
2003: Nap Alexander; Mathy Marie-Jeanne; Balt Jippe C; Pfaffendorf Martin; van Zwieten Pieter A
Pre- and postsynaptic inhibitory potencies of the angiotensin AT1 receptor antagonists eprosartan and candesartan.
European journal of pharmacology 2003;469(1-3):117-24.
2003: Sand Carsten; Peters Stephan L M; Pfaffendorf Martin; van Zwieten Pieter A
Effects of hypochlorite and hydrogen peroxide on cardiac autonomic receptors and vascular endothelial function.
Clinical and experimental pharmacology & physiology 2003;30(4):249-53.
2003: Balt Jippe C; Belterman Charly N W; Mathy Marie-Jeanne; Nap Alexander; Baartscheer Anton; Pfaffendorf Martin; Van Zwieten Pieter A
Decreased facilitation by angiotensin II of noradrenergic neurotransmission in isolated mesenteric artery of rabbits with chronic heart failure.
Journal of cardiovascular pharmacology 2003;41(3):356-62.
2003: Streefkerk J O; Pfaffendorf M; van Zwieten P A
Vasopressin-induced facilitation of adrenergic responses in the rat mesenteric artery is V1-receptor dependent.
Autonomic & autacoid pharmacology 2003;23(1):35-41.
2003: Balt Jippe C; Mathy Marie-Jeanne; Pfaffendorf Martin; van Zwieten Pieter A
Sympatho-inhibitory actions of irbesartan in pithed spontaneously hypertensive and Wistar-Kyoto rats.
Fundamental & clinical pharmacology 2003;17(1):83-91.
2002: Streefkerk Jörn O; de Groot Annemieke A; Pfaffendorf Martin; van Zwieten Pieter A
Influence of the nature of pre-contraction on the responses to commonly employed vasodilator agents in rat-isolated aortic rings.
Fundamental & clinical pharmacology 2002;16(6):485-94.
2002: Balt Jippe C; Mathy Marie-Jeanne; Nap Alex; Pfaffendorf Martin; van Zwieten Pieter A
Involvement of the AT(2)-receptor in angiotensin II-induced facilitation of sympathetic neurotransmission.
Journal of the renin-angiotensin-aldosterone system : JRAAS 2002;3(3):181-7.
2002: Nap Alexander; Balt Jippe C; Pfaffendorf Martin; Van Zwieten Pieter A
Sympatholytic properties of several AT1-receptor antagonists in the isolated rabbit thoracic aorta.
Journal of hypertension 2002;20(9):1821-8.
2002: Peters Stephan L M; Sand Carsten; Michel Martin C; Pfaffendorf Martin; Van Zwieten Pieter A
A mitogen-activated protein kinase is involved in the inotropic but not chronotropic actions of adrenoceptor agonists and endothelin-1.
Naunyn-Schmiedeberg's archives of pharmacology 2002;366(2):189-91.
2002: Balt Jippe C; Mathy Marie-Jeanne; Nap Alexander; Pfaffendorf Martin; van Zwieten Pieter A
Prejunctional and postjunctional inhibitory actions of eprosartan and candesartan in the isolated rabbit mesenteric artery.
Journal of cardiovascular pharmacology 2002;40(1):50-7.
2002: Balt Jippe C; Mathy Marie-Jeanne; Pfaffendorf Martin; van Zwieten Peter A
Sympatho-inhibitory properties of various AT1 receptor antagonists.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 2002;20(5):S3-11.
2002: van Zwieten Peter A; Julius Stevo
AT1 blockers: are there alternative pathways reducing cardiovascular risk? Introduction.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 2002;20(5):S1.
2002: Streefkerk Jörn O; Mathy Marie-Jeanne; Pfaffendorf Martin; van Zwieten Pieter A
Vasopressin-induced presynaptic facilitation of sympathetic neurotransmission in the pithed rat.
Journal of hypertension 2002;20(6):1175-80.
2002: Sand C; Peters S L M; Mathy M J; Pfaffendorf M; van Zwieten P A
The effects of hypochlorite-induced oxidative stress on presynaptic M2-receptors at sympathetic nerve endings in the rat tail artery.
Autonomic & autacoid pharmacology 2002;22(2):127-32.
2001: Balt J C; Mathy M J; Pfaffendorf M; van Zwieten P A
Inhibition of facilitation of sympathetic neurotransmission and angiotensin II-induced pressor effects in the pithed rat: comparison between valsartan, candesartan, eprosartan and embusartan.
Journal of hypertension 2001;19(12):2241-50.
2001: Nap A; Pfaffendorf M; van Zwieten P A
Characterisation of a modified approach to the study of sympathetic neurotransmission and its presynaptic modulation in the isolated rabbit thoracic aorta.
Journal of pharmacological and toxicological methods 2001;46(3):145-51.
2001: Sand C; Peters S L; Pfaffendorf M; van Zwieten P A
Oxidative stress impairs the haemodynamic activity of cardiovascular agents with antioxidant properties.
Naunyn-Schmiedeberg's archives of pharmacology 2001;364(5):454-61.
2001: Peters S L; Sand C; Batinik H D; Pfaffendorf M; van Zwieten P A
Reactive oxygen species potentiate the negative inotropic effect of cardiac M2-muscarinic receptor stimulation.
Naunyn-Schmiedeberg's archives of pharmacology 2001;364(2):166-71.
2001: Balt J C; Mathy M J; Nap A; Pfaffendorf M; van Zwieten P A
Effect of the AT1-receptor antagonists losartan, irbesartan, and telmisartan on angiotensin II-induced facilitation of sympathetic neurotransmission in the rat mesenteric artery.
Journal of cardiovascular pharmacology 2001;38(1):141-8.
2001: Li Q; Pfaffendorf M; van Zwieten P A
Different types of antagonism by losartan and irbesartan on the effects of angiotensin II and its degradation products in rabbit arteries.
Fundamental & clinical pharmacology 2001;15(2):143-50.
2001: Balt J C; Mathy M J; Pfaffendorf M; van Zwieten P A
Inhibition of angiotensin II-induced facilitation of sympathetic neurotransmission in the pithed rat: a comparison between losartan, irbesartan, telmisartan, and captopril.
Journal of hypertension 2001;19(3):465-73.
2001: van Zwieten P A
Centrally acting imidazoline I1-receptor agonists: do they have a place in the management of hypertension?
American journal of cardiovascular drugs : drugs, devices, and other interventions 2001;1(5):321-6.
2001: van der Lee R; Pfaffendorf M; Koopmans R P; van Lieshout J J; van Montfrans G A; van Zwieten P A
Comparison of the time courses and potencies of the vasodilator effects of nifedipine and felodipine in the human forearm.
Blood pressure 2001;10(4):217-22.
2000: Heijenbrok F J; Mathy M J; Pfaffendorf M; van Zwieten P A
The influence of chronic inhibition of nitric oxide synthesis on contractile and relaxant properties of rat carotid and mesenteric arteries.
Naunyn-Schmiedeberg's archives of pharmacology 2000;362(6):504-11.
2000: van der Lee R; Pfaffendorf M; van Zwieten P A
The differential time courses of the vasodilator effects of various 1,4-dihydropyridines in isolated human small arteries are correlated to their lipophilicity.
Journal of hypertension 2000;18(11):1677-82.
2000: Heijenbrok F J; Mathy M J; Pfaffendorf M; van Zwieten P A
Beta-adrenergic responses are significantly enhanced in rat carotid artery with intimal hyperplasia.
Naunyn-Schmiedeberg's archives of pharmacology 2000;362(3):276-83.
2000: Pfaffendorf M; Batink H D; Tränkle C; Mohr K; van Zwieten P A
Probing the selectivity of allosteric modulators of muscarinic receptors at other G-protein-coupled receptors.
Journal of autonomic pharmacology 2000;20(1):55-62.
2000: Pfaffendorf M; Mathy M J; van der Lee R; van Zwieten P A
Evidence for a sympatholytic effect of mibefradil in the pithed rat preparation.
Journal of hypertension 2000;18(2):203-7.
2000: Peters S L; Mathy M J; Pfaffendorf M; van Zwieten P A
Reactive oxygen species-induced aortic vasoconstriction and deterioration of functional integrity.
Naunyn-Schmiedeberg's archives of pharmacology 2000;361(2):127-33.
2000: van der Lee R; Pfaffendorf M; De Mey J G; van Zwieten P A
Inhibitory effect of mibefradil on contractions induced by sympathetic neurotransmitter release in the rat tail artery.
Naunyn-Schmiedeberg's archives of pharmacology 2000;361(1):74-9.
1999: van Zwieten P A
Beneficial interactions between pharmacological, pathophysiological and hypertension research.
Journal of hypertension 1999;17(12 Pt 2):1787-97.
1999: van Zwieten P A
The renaissance of centrally acting antihypertensive drugs.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1999;17(3):S15-21.
1999: van Zwieten P A; Julius S
The importance of the sympathetic nervous system in hypertension. Introduction.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1999;17(3):S1.
1999: van Zwieten P A
Centrally acting antihypertensive drugs. Present and future.
Clinical and experimental hypertension (New York, N.Y. : 1993) 1999;21(5-6):859-73.
1999: Van Zwieten P A; Peters S L
Central I1-imidazoline receptors as targets of centrally acting antihypertensive drugs. Clinical pharmacology of moxonidine and rilmenidine.
Annals of the New York Academy of Sciences 1999;881():420-9.
1999: Baan J; Chang P C; Vermeij P; Pfaffendorf M; van Zwieten P A
Effects of sodium depletion on the role of AT1- and alpha-adrenergic receptors in the regulation of forearm vascular tone in humans.
Journal of hypertension 1999;17(2):229-35.
1999: van Zwieten P A
Diabetes and hypertension: experimental models for pharmacological studies.
Clinical and experimental hypertension (New York, N.Y. : 1993) 1999;21(1-2):1-16.
1999: Van Zwieten P A; Hansson L
Calcium antagonists and safety: the turning of the tide.
Blood pressure 1999;8(1):5-8.
1999: van der Lee R; Pfaffendorf M; van Zwieten P A
Comparative effects of mibefradil and other calcium antagonists on resistance arteries of different end organs.
Fundamental & clinical pharmacology 1999;13(2):198-203.
1999: Baan J; Pfaffendorf M; van der Wal A C; Chang P C; van Zwieten P A
Influence of losartan and nicardipine on the contractile responses of human subcutaneous arteries and veins to angiotensin II.
Fundamental & clinical pharmacology 1999;13(1):43-9.
1998: van Zwieten P A
Introduction: the role of calcium antagonists.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1998;16(6):S1-2.
1998: Baan J; Chang P C; Vermeij P; Pfaffendorf M; van Zwieten P A
Effects of angiotensin II and losartan in the forearm of patients with essential hypertension.
Journal of hypertension 1998;16(9):1299-305.
1998: Li Q; Zhang J; Loro J F; Pfaffendorf M; van Zwieten P A
Bradykinin B2-receptor-mediated positive chronotropic effect of bradykinin in isolated rat atria.
Journal of cardiovascular pharmacology 1998;32(3):452-6.
1998: Peters S L; Batink H D; Michel M C; Pfaffendorf M; van Zwieten P A
Possible mechanism of the negative inotropic effect of alpha1-adrenoceptor agonists in rat isolated left atria after exposure to free radicals.
British journal of pharmacology 1998;123(5):952-8.
1998: Heijenbrok F J; van der Wal A C; Pfaffendorf M; van Zwieten P A
Morphologic and functional consequences of intimal hyperplasia in the rat carotid artery.
Naunyn-Schmiedeberg's archives of pharmacology 1998;357(2):133-42.
1998: Baan J; Chang P C; Vermeij P; Pfaffendorf M; van Zwieten P A
Venoconstriction by angiotensin II in the human forearm is inhibited by losartan but not by nicardipine.
Journal of cardiovascular pharmacology 1998;31(1):50-5.
1998: van Zwieten P A
The pharmacological properties of lipophilic calcium antagonists.
Blood pressure. Supplement 1998;2():5-9.
1998: van der Lee R; Kam K L; Pfaffendorf M; van Zwieten P A
Differential time course of the vasodilator action of various calcium antagonists.
Fundamental & clinical pharmacology 1998;12(6):607-12.
1998: van Zwieten P A
Pharmacological profile of barnidipine: a single optical isomer dihydropyridine calcium antagonist.
Blood pressure. Supplement 1998;1():5-8.
1997: Baan J; Chang P C; Vermeij P; Pfaffendorf M; van Zwieten P A
Influence of indomethacin and L-NMMA on vascular tone and angiotensin II-induced vasoconstriction in the human forearm.
Blood pressure 1997;6(5):279-85.
1997: Zwaveling J; Pfaffendorf M; van Zwieten P A
The influence of hyperthyroidism on vasoconstrictor and vasodilator responses in isolated coronary and renal resistance arteries.
Pharmacology 1997;55(3):117-25.
1997: Pfaffendorf M; Bruning T A; Batnik H D; van Zwieten P A
The interaction between methylene blue and the cholinergic system.
British journal of pharmacology 1997;122(1):95-8.
1997: Hüsken B C; van der Wal A C; Teeling P; Mathy M J; Mertens M J; Pul A J; Pfaffendorf M; van Zwieten P A
Heterogeneity in morphological characteristics of coronary arteries and aortae in various models of hypertension.
Blood pressure 1997;6(4):242-9.
1997: Li Q; Feenstra M; Pfaffendorf M; Eijsman L; van Zwieten P A
Comparative vasoconstrictor effects of angiotensin II, III, and IV in human isolated saphenous vein.
Journal of cardiovascular pharmacology 1997;29(4):451-6.
1997: Van Zwieten P A; Hansson L; Epstein M
Slowly acting calcium antagonists and their merits.
Blood pressure 1997;6(2):78-80.
1997: Peters S L; Pfaffendorf M; van Zwieten P A
The influence of oxidative stress on various inotropic responses in isolated rat left atria.
Naunyn-Schmiedeberg's archives of pharmacology 1997;355(3):390-7.
1997: van Zwieten P A
Central imidazoline (I1) receptors as targets of centrally acting antihypertensives: moxonidine and rilmenidine.
Journal of hypertension 1997;15(2):117-25.
1997: Beenen O H; Batink H D; Pfaffendorf M; van Zwieten P A
Beta-andrenoceptors in the hearts of diabetic-hypertensive rats: radioligand binding and functional experiments.
Blood pressure 1997;6(1):44-51.
1997: van Zwieten P A
Current and newer approaches in the drug treatment of congestive heart failure.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1997;10(6):693-702.
1997: Dubois E A; Somsen G A; van den Bos J C; Janssen A G; Batink H D; Boer G J; van Royen E A; Pfaffendorf M; van Zwieten P A
Development of radioligands for the imaging of cardiac beta-adrenoceptors using SPECT. Part II: Pharmacological characterization in vitro and in vivo of new 123I-labeled beta-adrenoceptor antagonists.
Nuclear medicine and biology 1997;24(1):9-13.
1997: van den Bos J C; van Doremalen P A; Dubois E A; Somsen G A; Vekemans J A; Janssen A G; Boer G J; Pfaffendorf M; van Royen E A; van Zwieten P A
Development of radioligands for the imaging of cardiac beta-adrenoceptors using SPECT. Part I: Asymmetric synthesis and structural characterization of five new iodine-containing beta-adrenoceptor antagonist derivatives.
Nuclear medicine and biology 1997;24(1):1-7.
1997: van Zwieten P A
Centrally acting antihypertensives: a renaissance of interest. Mechanisms and haemodynamics.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1997;15(1):S3-8.
1997: Hüsken B C; Pfaffendorf M; van Zwieten P A
Contribution of ATP-sensitive potassium channels to beta-adrenoceptor-mediated responses.
Naunyn-Schmiedeberg's archives of pharmacology 1997;355(1):97-102.
1997: Hüsken B C; Pfaffendorf M; van Zwieten P A
ATP-sensitive potassium channels in isolated rat aorta during physiologic, hypoxic, and low-glucose conditions.
Journal of cardiovascular pharmacology 1997;29(1):130-5.
1997: Van Zwieten P A
Endothelial dysfunction in hypertension. A critical evaluation.
Blood pressure. Supplement 1997;2():67-70.
1997: Zwaveling J; Pfaffendorf M; van Zwieten P A
The direct effects of thyroid hormones on rat mesenteric resistance arteries.
Fundamental & clinical pharmacology 1997;11(1):41-6.
1997: van Zwieten P A
Recent changes in the treatment of congestive heart failure. Introduction.
Cardiology 1997;88 Suppl 2():1.
1996: Zwaveling J; Batink H D; de Jong J; Winkler Prins E A; Pfaffendorf M; van Zwieten P A
Thyroid hormone modulates inotropic responses, alpha-adrenoceptor density and catecholamine concentrations in the rat heart.
Naunyn-Schmiedeberg's archives of pharmacology 1996;354(6):755-64.
1996: Bruning T A; Chang P C; Kemme M J; Vermeij P; Pfaffendorf M; van Zwieten P A
Comparison of cholinergic vasodilator responses to acetylcholine and methacholine in the human forearm.
Blood pressure 1996;5(6):333-41.
1996: Baan J; Chang P C; Vermeij P; Pfaffendorf M; van Zwieten P A
Effects of losartan on vasoconstrictor responses to angiotensin II in the forearm vascular bed of healthy volunteers.
Cardiovascular research 1996;32(5):973-9.
1996: van Zwieten P A
Clinical pharmacology of calcium antagonists as antihypertensive and anti-anginal drugs.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1996;14(3):S3-9.
1996: Vroom M B; van Wezel H B; vd Brink R B; vd Lee R; Eijsman L; Visser C A; van Zwieten P A
Effects of dobutamine and enoximone on transmitral and pulmonary venous flow characteristics in patients with left ventricular dysfunction after coronary artery bypass grafting.
Journal of cardiothoracic and vascular anesthesia 1996;10(6):756-63.
1996: Beenen O H; Pfaffendorf M; van Zwieten P A
Influence of the low thyroid state in diabetes mellitus on cardiac function and inotropic responsiveness to alpha 1-adrenoceptor stimulation: comparison with the role of hypothyroidism alone.
Journal of cardiovascular pharmacology 1996;28(4):553-7.
1996: Beenen O H; Mathy M J; Pfaffendorf M; van Zwieten P A
Vascular responsiveness in isolated perfused kidneys of diabetic hypertensive rats.
Journal of hypertension 1996;14(9):1125-30.
1996: van Zwieten P A
The role of public health authorities, scientific societies and the pharmaceutical industry in planning and conducting intervention trials.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1996;14(2):S135-9; discussion S139-40.
1996: Li Q; Zhang J; Pfaffendorf M; van Zwieten P A
Direct positive chronotropic effects of angiotensin II and angiotensin III in pithed rats and in rat isolated atria.
British journal of pharmacology 1996;118(7):1653-8.
1996: Dubois E A; van den Bos J C; Doornbos T; van Doremalen P A; Somsen G A; Vekemans J A; Janssen A G; Batink H D; Boer G J; Pfaffendorf M; van Royen E A; van Zwieten P A
Synthesis and in vitro and in vivo characteristics of an iodinated analogue of the beta-adrenoceptor antagonist carazolol.
Journal of medicinal chemistry 1996;39(17):3256-62.
1996: Dubois E A; Kam K L; Somsen G A; Boer G J; de Bruin K; Batink H D; Pfaffendorf M; van Royen E A; van Zwieten P A
Cardiac iodine-123 metaiodobenzylguanidine uptake in animals with diabetes mellitus and/or hypertension.
European journal of nuclear medicine 1996;23(8):901-8.
1996: Beenen O H; Mathy M J; Pfaffendorf M; van Zwieten P A
Influence of nifedipine on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed diabetic hypertensive rats.
Journal of hypertension 1996;14(7):847-53.
1996: van Zwieten P A
Modulation of sympathetic outflow by centrally acting antihypertensive drugs.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1996;10 Suppl 1():283-9.
1996: Dubois E A; Somsen G A; van den Bos J C; Janssen A G; Boer G J; Batink H D; van Royen E A; Pfaffendorf M; van Zwieten P A
Pharmacologic characterization in vitro and in vivo of iodine 123-labeled derivatives of the beta-adrenoceptor antagonist CGP12177, designed for the imaging of cardiac beta-receptors.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 1996;3(3):242-52.
1996: van der Stroom J G; van Wezel H B; Vergroesen I; Kal J E; Koolen J J; Dijkhuis J P; Swaan A; Porsius M; Kleinjans H A; van Zwieten P A
Comparison of the effects of urapidil and sodium nitroprusside on haemodynamic state, myocardial metabolism and function in patients during coronary artery surgery.
British journal of anaesthesia 1996;76(5):645-51.
1996: van Zwieten P A
New central mediators as targets of centrally acting antihypertensive drugs.
Clinical and experimental hypertension (New York, N.Y. : 1993) 1996;18(3-4):291-303.
1996: Zwaveling J; Prins E A; Maas M A; Pfaffendorf M; Van Zwieten P A
The influence of hyperthyroidism on pharmacologically induced contractions of isolated resistance arteries.
European journal of pharmacology 1996;300(1-2):91-7.
1996: Zwaveling J; Winkler Prins E A; Pfaffendorf M; van Zwieten P A
The influence of hyperthyroidism on beta-adrenoceptor-mediated relaxation of isolated small mesenteric arteries.
Naunyn-Schmiedeberg's archives of pharmacology 1996;353(4):438-44.
1996: Van Zwieten P A; Kam K L; Pijl A J; Hendriks M G; Beenen O H; Pfaffendorf M
Hypertensive diabetic rats in pharmacological studies.
Pharmacological research : the official journal of the Italian Pharmacological Society 1996;33(2):95-105.
1996: Somsen G A; Dubois E A; Brandsma K; de Jong J; van der Wouw P A; Batink H D; van Royen E A; Lie K I; van Zwieten P A
Cardiac sympathetic neuronal function in left ventricular volume and pressure overload.
Cardiovascular research 1996;31(1):132-8.
1996: Beenen O H; Mathy M J; Pfaffendorf M; van Zwieten P A
Opposite influences of hypertension and diabetes mellitus on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed rats.
Blood pressure 1996;5(1):57-63.
1996: Vroom M B; Pfaffendorf M; van Wezel H B; van Zwieten P A
Effect of phosphodiesterase inhibitors on human arteries in vitro.
British journal of anaesthesia 1996;76(1):122-9.
1996: Kam K L; Hendriks M G; Pijl A J; van Marle J; van Veen H A; Pfaffendorf M; van Zwieten P A
Contractile responses to various stimuli in isolated resistance vessels from simultaneously hypertensive and streptozotocin-diabetic rats.
Journal of cardiovascular pharmacology 1996;27(1):167-75.
1996: van Zwieten P A; Pfaffendorf M; Mancia G
Attempts to improve the selectivity of calcium antagonistic drugs.
Blood pressure. Supplement 1996;5():7-9.
1996: van Zwieten P A
From alpha and beta to I1: an overview of sympathetic receptors involved in blood pressure control targets for drug treatment.
Journal of cardiovascular pharmacology 1996;27 Suppl 3():S5-10.
1996: Kam K L; Pfaffendorf M; van Zwieten P A
Pharmacodynamic behaviour of isolated resistance vessels obtained from hypertensive-diabetic rats.
Fundamental & clinical pharmacology 1996;10(4):329-36.
1995: Hüsken B C; Vroom M B; Timmenga E J; Pfaffendorf M; Van Zwieten P A
Relaxant effect of levcromakalim in isolated human small subcutaneous arteries.
European journal of pharmacology 1995;287(3):313-6.
1995: Mertens M J; Batink H D; Mathy M J; Pfaffendorf M; van Zwieten P A
Reduced muscarinic cholinoceptor density and sensitivity in various models of experimental cardiac hypertrophy.
Journal of autonomic pharmacology 1995;15(6):465-74.
1995: Li Q; Zhang L; Pfaffendorf M; van Zwieten P A
Comparative effects of angiotensin II and its degradation products angiotensin III and angiotensin IV in rat aorta.
British journal of pharmacology 1995;116(7):2963-70.
1995: Beenen O H; Pfaffendorf M; van Zwieten P A
Contractile responses to various inotropic agents in isolated hearts obtained from hypertensive diabetic rats.
Blood pressure 1995;4(6):372-8.
1995: Vischjager M; Van Gulik T M; Pfaffendorf M; Van Zwieten P A; Van Marle J; Kromhout J G; Klopper P J; Jacobs M J
Morphology and function of dog arterial grafts preserved in UW-solution.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 1995;10(4):431-9.
1995: van Zwieten P A; Hendriks M G; Pfaffendorf M; Bruning T A; Chang P C
The parasympathetic system and its muscarinic receptors in hypertensive disease.
Journal of hypertension 1995;13(10):1079-90.
1995: Kemme M J; Bruning T A; Chang P C; Van Zwieten P A
Cholinergic receptor-mediated responses in the arteriolar and venous vascular beds of the human forearm.
Blood pressure 1995;4(5):293-9.
1995: Bruning T A; Chang P C; Hendriks M G; Vermeij P; Pfaffendorf M; van Zwieten P A
In vivo characterization of muscarinic receptor subtypes that mediate vasodilatation in patients with essential hypertension.
Hypertension 1995;26(1):70-7.
1995: van Zwieten P A; Safar M; Laurent S; Pfaffendorf M; Hendriks M G; Bruning T A
New insights into the role of endothelial dysfunction in hypertension.
Journal of hypertension 1995;13(7):713-6.
1995: Koch K T; Düren D R; van Zwieten P A
Long-term antiarrhythmic efficacy and safety of d-sotalol in patients with ventricular tachycardia and a low ejection fraction.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1995;9(3):437-43.
1995: Vroom M B; van Wezel H B; Visser C A; Eijsman L; van Zwieten P A
Hemodynamic effects of the novel selective cAMP-phosphodiesterase III inhibitor R 80122 in anesthetized patients with moderate left ventricular dysfunction before coronary artery bypass grafting.
Journal of cardiothoracic and vascular anesthesia 1995;9(3):272-7.
1995: Pijl A J; Van Wezel H B; Koolen J J; Piek J J; Koch K; Swaan A; David G K; Visser C A; Van Zwieten P A
The negative inotropic and chronotropic effects of intravenous R 56865 during percutaneous transluminal coronary angioplasty.
British journal of clinical pharmacology 1995;39(5):531-5.
1995: Zhang J; Pfaffendorf M; van Zwieten P A
Hemodynamic effects of angiotensin II and the influence of angiotensin receptor antagonists in pithed rabbits.
Journal of cardiovascular pharmacology 1995;25(5):724-31.
1995: Mertens M J; Pfaffendorf M; Van Zwieten P A
Sensitivity of cardiac tissues with moderate and advanced hypertrophy to calcium ions.
General pharmacology 1995;26(2):399-406.
1995: van Zwieten P A; Doods H N
Muscarinic receptors and drugs in cardiovascular medicine.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1995;9(1):159-67.
1995: Van Zwieten P A
Pharmacological backgrounds of the drug treatment of hypertension in the elderly.
Blood pressure. Supplement 1995;3():15-20.
1995: Zhang J; Pfaffendorf M; Zhang J S; van Zwieten P A
Influence of the vascular endothelium on angiotensin II-induced contractions in rabbit renal artery.
Fundamental & clinical pharmacology 1995;9(1):25-9.
1995: van den Ende R; Guttmann I; Scheufler E; Pfaffendorf M; van Zwieten P A
Effect of Na+ reduction and monensin on ion content and contractile response in normoxic and ischaemic reperfused rat hearts.
Fundamental & clinical pharmacology 1995;9(2):161-8.
1995: van Es N M; Bruning T A; Camps J; Chang P C; Blauw G J; Ferrari M D; Saxena P R; van Zwieten P A
Assessment of peripheral vascular effects of antimigraine drugs in humans.
Cephalalgia : an international journal of headache 1995;15(4):288-91.
1994: Pijl A J; van der Wal A C; Mathy M J; Kam K L; Hendriks M G; Pfaffendorf M; van Zwieten P A
Streptozotocin-induced diabetes mellitus in spontaneously hypertensive rats: a pathophysiological model for the combined effects of hypertension and diabetes.
Journal of pharmacological and toxicological methods 1994;32(4):225-33.
1994: van Zwieten P A; Chalmers J P
Different types of centrally acting antihypertensives and their targets in the central nervous system.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1994;8(6):787-99.
1994: Hüsken B C; Hendriks M G; Pfaffendorf M; Van Zwieten P A
Effects of aging and hypertension on the reactivity of isolated conduit and resistance vessels.
Microvascular research 1994;48(3):303-15.
1994: Kam K L; Pfaffendorf M; van Zwieten P A
Drug-induced endothelium-dependent and -independent relaxations in isolated resistance vessels taken from simultaneously hypertensive and streptozotocin-diabetic rats.
Blood pressure 1994;3(6):418-27.
1994: van Zwieten P A
Amlodipine: an overview of its pharmacodynamic and pharmacokinetic properties.
Clinical cardiology 1994;17(9 Suppl 3):III3-6.
1994: Bruning T A; Chang P C; Blauw G J; Vermeij P; Van Zwieten P A
Interactions between serotonin and endogenous and exogenous noradrenaline in the human forearm.
Blood pressure 1994;3(5):309-18.
1994: Zhang J; Van Meel J C; Pfaffendorf M; Zhang J; Van Zwieten P A
Endothelium-dependent, nitric oxide-mediated inhibition of angiotensin II-induced contractions in rabbit aorta.
European journal of pharmacology 1994;262(3):247-53.
1994: Bruning T A; van Zwieten P A; Blauw G J; Chang P C
No functional involvement of 5-hydroxytryptamine1A receptors in nitric oxide-dependent dilatation caused by serotonin in the human forearm vascular bed.
Journal of cardiovascular pharmacology 1994;24(3):454-61.
1994: Hüsken B C; Mertens M J; Pfaffendorf M; Van Zwieten P A
The influence of coarctation hypertension on the pharmacodynamic behaviour of rat isolated conduit vessels.
Blood pressure 1994;3(4):255-9.
1994: Zhang J; Pfaffendorf M; van Zwieten P A
Effect of various angiotensin receptor antagonists on cardiovascular responses to angiotensin II in pithed rats.
Journal of cardiovascular pharmacology 1994;24(1):108-13.
1994: Pijl A J; Hendriks M G; Kam K L; Paffendorf M; van Zwieten P A
Effects of R 56865 on postischemic ventricular function in isolated rat working heart preparations obtained from healthy, diabetic and hypertensive animals.
Naunyn-Schmiedeberg's archives of pharmacology 1994;349(6):619-26.
1994: Zhang J S; Van Meel J C; Pfaffendorf M; Van Zwieten P A
Different types of angiotensin II receptor antagonism induced by BIBS 222 in the rat portal vein and rabbit aorta; the influence of receptor reserve.
The Journal of pharmacology and experimental therapeutics 1994;269(2):509-14.
1994: Bruning T A; Hendriks M G; Chang P C; Kuypers E A; van Zwieten P A
In vivo characterization of vasodilating muscarinic-receptor subtypes in humans.
Circulation research 1994;74(5):912-9.
1994: Zhang J S; van Meel J C; Pfaffendorf M; van Zwieten P A
Inhibitory effect of dithiothreitol on angiotensin II-induced contractions mediated by AT1-receptors in rat portal vein and rabbit aorta.
Naunyn-Schmiedeberg's archives of pharmacology 1994;349(5):538-42.
1994: Zhang J S; Van Meel J C; Pfaffendorf M; Zhang J; Van Zwieten P A
Calcium dependency of the AT1-receptor mediated effects in the rat portal vein: influence of calcium antagonists.
Naunyn-Schmiedeberg's archives of pharmacology 1994;349(4):437-42.
1994: Pijl A J; Hendriks M G; Kam K L; Pfaffendorf M; van Zwieten P A
Antiischemic effects of nifedipine in isolated working heart preparations of healthy, diabetic, and hypertensive rats.
Journal of cardiovascular pharmacology 1994;23(3):379-86.
1994: Zhang J; Pfaffendorf M; Zhang J S; Van Zwieten P A
A non-competitive type of angiotensin-receptor antagonism by losartan in renal artery preparations.
European journal of pharmacology 1994;252(3):337-40.
1994: van den Ende R; Batink H D; Michel M C; van Zwieten P A
Influence of ischaemia and reperfusion on cardiac signal transduction. G protein content, adenylyl cyclase activity, cyclic AMP content, and forskolin and dibutyryl cyclic AMP-induced inotropy in the rat Langendorff heart.
Fundamental & clinical pharmacology 1994;8(5):408-16.
1994: Van der Stroom J G; Van Wezel H B; Koolen J J; Visser C A; Van Zwieten P A
Comparison of the effects of urapidil and nitroprusside on hemodynamics and myocardial function in hypertension following cardiac surgery.
Blood pressure. Supplement 1994;4():31-8.
1994: Van Zwieten P A; Bruning T A
Comparison of the hemodynamic effects of urapidil and flesinoxan in healthy volunteers.
Blood pressure. Supplement 1994;4():19-24.
1993: Hendriks M G; Pfaffendorf M; van Zwieten P A
The effect of muscarinic receptor alkylation on endothelium-dependent vasodilation in SHR.
Blood pressure 1993;2(4):332-8.
1993: van Zwieten P A; Pfaffendorf M
Pharmacology of the dihydropyridine calcium antagonists: relationship between lipophilicity and pharmacodynamic responses.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1993;11(6):S3-8.
1993: Hendriks M G; Kam K L; Pijl A J; Pfaffendorf M; van Zwieten P A
The effects of hypertension and diabetes mellitus on the vascular reactivity of perfused mesenteric resistance arteries.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1993;11(5):S268-9.
1993: Kam K L; Hendriks M G; Pijl A J; Pfaffendorf M; van Zwieten P A
Spontaneously hypertensive rats with diabetes: effects of some vasoconstrictors on isolated small arteries.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1993;11(5):S120-1.
1993: Hendriks M G; Pfaffendorf M; van Zwieten P A
Characterization of the muscarinic receptors in the mesenteric vascular bed of spontaneously hypertensive rats.
Journal of hypertension 1993;11(12):1329-35.
1993: Kam K L; Pfaffendorf M; van Zwieten P A
The influence of high glucose levels and/or hyperosmolarity on rat isolated aorta.
Journal of pharmacological and toxicological methods 1993;30(3):153-7.
1993: van Zwieten P A
New avenues in antihypertensive drug treatment.
Clinical and experimental hypertension (New York, N.Y. : 1993) 1993;15(6):1205-20.
1993: Hendriks M G; Pfaffendorf M; van Zwieten P A
The role of nitric oxide and potassium channels in endothelium-dependent vasodilation in SHR.
Blood pressure 1993;2(3):233-43.
1993: Pijl A J; Pfaffendorf M; van Zwieten P A
Hemodynamic and antiischemic effects of nifedipine, lacidipine, and nisoldipine in rat isolated working heart.
Journal of cardiovascular pharmacology 1993;22(3):381-7.
1993: Bruning T A; Chang P C; Blauw G J; Vermeij P; van Zwieten P A
Serotonin-induced vasodilatation in the human forearm is mediated by the "nitric oxide-pathway": no evidence for involvement of the 5-HT3-receptor.
Journal of cardiovascular pharmacology 1993;22(1):44-51.
1993: Zhang J; Pfaffendorf M; van Zwieten P A
Positive inotropic action of angiotensin II in the pithed rat.
Naunyn-Schmiedeberg's archives of pharmacology 1993;347(6):658-63.
1993: Zhang J; Van Meel J C; Van Zwieten P A
Antihypertensive activity of the novel, nonpeptide angiotensin II receptor antagonists BIBS 39 and BIBS 222 in conscious renal hypertensive rats.
Pharmacology 1993;46(5):241-7.
1993: Schwietert R; Wilhelm D; Wilffert B; van Zwieten P A
Functional study on the effects of nifedipine, cromakalim, and the absence of extracellular Ca2+ on alpha 1-adrenoceptor-mediated excitation-contraction coupling in isolated rat portal vein: comparison with depolarization-mediated excitation-contraction coupling.
Journal of cardiovascular pharmacology 1993;21(5):739-48.
1993: Heijnis J B; van Zwieten P A
Effects of calcium antagonists on K(+)-induced contraction in isolated aorta from diabetic and age-matched control rats.
Pharmacology 1993;46(4):193-7.
1993: van Zwieten P A; van Wezel H B
Antihypertensive drug treatment in the perioperative period.
Journal of cardiothoracic and vascular anesthesia 1993;7(2):213-26.
1993: van Zwieten P A
An overview of the pharmacodynamic properties and therapeutic potential of combined alpha- and beta-adrenoceptor antagonists.
Drugs 1993;45(4):509-17.
1993: van Zwieten P A; Pfaffendorf M
Similarities and differences between calcium antagonists: pharmacological aspects.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1993;11(1):S3-11.
1993: Hendriks M G; Kam K L; Pijl A J; Pfaffendorf M; van Zwieten P A
The effects of hypertension and diabetes mellitus on the vascular reactivity of resistance arteries.
Blood pressure 1993;2(1):69-76.
1993: Pfaffendorf M; Mathy M J; van Zwieten P A
In vitro effects of nifedipine, nisoldipine, and lacidipine on rat isolated coronary small arteries.
Journal of cardiovascular pharmacology 1993;21(3):496-502.
1993: Zhang J S; Van Meel J C; Pfaffendorf M; Van Zwieten P A
Characterization of the angiotensin II-receptor subtype in the longitudinal smooth muscle of the rat portal vein.
Naunyn-Schmiedeberg's archives of pharmacology 1993;347(2):220-4.
1993: Pfaffendorf M; Mathy M J; van Zwieten P A
Effects of manidipine and other calcium antagonists on rat renal arcuate arteries.
American heart journal 1993;125(2 Pt 2):571-7.
1993: van Zwieten P A
Protective effects of calcium antagonists in different organs and tissues.
American heart journal 1993;125(2 Pt 2):566-71.
1993: Pfaffendorf M; Van Zwieten P A
Mediation by the same muscarinic receptor subtype of phasic and tonic contractile activities in the rat isolated portal vein.
British journal of pharmacology 1993;108(1):132-8.
1993: Zhang J; Van Meel J C; Pfaffendorf M; Van Zwieten P A
Cholera toxin but not pertussis toxin inhibits angiotensin II-enhanced contractions in the rat portal vein.
European journal of pharmacology 1993;230(1):95-7.
1993: Pijl A J; Pfaffendorf M; Mathy M J; van Zwieten P A
Cardioprotection by nifedipine in isolated working hearts: a comparative study on three different types of experimental ischemia.
Journal of cardiovascular pharmacology 1993;21(1):70-6.
1993: van Zwieten P A
Pharmacodynamic profile of carvedilol.
Cardiology 1993;82 Suppl 3():19-23.
1993: Mertens M J; Pfaffendorf M; van Zwieten P A
Differential response of hypertrophied rat hearts to various alpha 1-adrenoceptor agonists.
Fundamental & clinical pharmacology 1993;7(2):93-101.
1992: van Zwieten P A
Comparative mechanisms of action of diuretic drugs in hypertension.
European heart journal 1992;13 Suppl G():2-4.
1992: Hendriks M G; Pfaffendorf M; Van Zwieten P A
Characterization of the muscarinic receptor subtype mediating vasodilation in the rat perfused mesenteric vascular bed preparation.
Journal of autonomic pharmacology 1992;12(6):411-20.
1992: van Zwieten P A
Development and trends in the drug treatment of essential hypertension.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1992;10(7):S1-12.
1992: Mertens M J; Pfaffendorf M; van Zwieten P A
Impaired vasodilator and chronotropic responses to 5-hydroxytryptamine in two models of hypertension-associated cardiac hypertrophy.
Blood pressure 1992;1(4):254-9.
1992: Mertens M J; Mathy M J; Pfaffendorf M; van Zwieten P A
Depressed inotropic response to beta-adrenoceptor agonists in the presence of advanced cardiac hypertrophy in hearts from rats with induced aortic stenosis and from spontaneously hypertensive rats.
Journal of hypertension 1992;10(11):1361-8.
1992: Heijnis J B; van Zwieten P A
Enhanced inotropic responsiveness to alpha 1-adrenoceptor stimulation in isolated working hearts from diabetic rats.
Journal of cardiovascular pharmacology 1992;20(4):559-62.
1992: Heijnis J B; Mathy M J; Pfaffendorf M; van Zwieten P A
Differential effects of alpha 1- and alpha 2-adrenoceptor agonists on peripheral vasoconstriction in pithed diabetic rats.
Journal of cardiovascular pharmacology 1992;20(4):554-8.
1992: Van Zwieten P A
The cholinergic nervous system in hypertension: a neglected issue.
Blood pressure 1992;1(2):68-71.
1992: van Zwieten P A; Blauw G J; van Brummelen P
Serotonergic receptors and drugs in hypertension.
Pharmacology & toxicology 1992;70(6 Pt 2):S17-22.
1992: Schwietert H R; Mathy M J; Wilhelm D; Wilffert B; Pfaffendorf M; van Zwieten P A
Alpha 1-adrenoceptor-mediated Ca(2+)-entry from the extracellular fluid and Ca(2+)-release from intracellular stores: no role for alpha 1A,B-adrenoceptor subtypes in the pithed rat.
Journal of autonomic pharmacology 1992;12(3):125-36.
1992: van Zwieten P A
Different types of centrally acting antihypertensive drugs.
European heart journal 1992;13 Suppl A():18-21.
1992: Mertens M J; Batink H D; Pfaffendorf M; van Zwieten P A
Impaired inotropic response to alpha 1- but not to beta-adrenoceptor stimulation in isolated hearts from spontaneously hypertensive rats.
Journal of hypertension 1992;10(2):143-8.
1992: Schwietert R; Wilhelm D; Wilffert B; Van Zwieten P A
The effect of some alpha-adrenoceptor antagonists on spontaneous myogenic activity in the rat portal vein and the putative involvement of ATP-sensitive K+ channels.
European journal of pharmacology 1992;211(1):87-95.
1992: van Zwieten P A
The role of alpha- and beta-adrenoceptor blockade in antihypertensive treatment.
The Clinical investigator 1992;70 Suppl 1():S7-12.
1991: Hendriks M G; Pfaffendorf M; van Zwieten P A
Characterization of the muscarinic receptors in the mesenteric vascular bed of spontaneously hypertensive rats.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1991;9(6):S188-9.
1991: van Zwieten P A
Adrenergic and muscarinergic receptors: classification, pathophysiological relevance and drug target.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1991;9(6):S18-27.
1991: Mertens M J; Pfaffendorf M; van Zwieten P A
Cardiac effects of serotonin in hypertension.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1991;9(6):S156-7.
1991: Heijnis J B; Coronel R; van Zwieten P A
The effects of calcium antagonists on extracellular potassium accumulation during global ischaemia in isolated perfused rat hearts.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1991;5(6):1035-41.
1991: Mertens M J; Batink H D; Pfaffendorf M; van Zwieten P A
Depressed inotropic response to alpha 1-adrenoceptor agonists in hearts from spontaneously hypertensive rats.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1991;9(6):S66-7.
1991: van den Ende R; Batink H D; Pfaffendorf M; van Zwieten P A
Discrepancies between inotropic responses and beta-adrenoceptor characteristics after global ischemia in isolated hearts.
Journal of cardiovascular pharmacology 1991;18(5):679-86.
1991: Heijnis J B; Mathy M J; van Zwieten P A
Effects of nifedipine on global myocardial ischemic injury in hearts from diabetic and age-matched control rats.
Journal of cardiovascular pharmacology 1991;18(4):542-7.
1991: Schwietert H R; Wilhelm D; Wilffert B; van Zwieten P A
Differences between full and partial alpha-adrenoceptor agonists in eliciting phasic and tonic types of responses in the longitudinal smooth muscle of the rat portal vein.
Naunyn-Schmiedeberg's archives of pharmacology 1991;344(2):206-12.
1991: van Heiningen P N; Batink H D; van Zwieten P A
Angiotensin II-induced increase in slowly exchanging 45Ca2+ in relation to contractile responses of rat and guinea-pig aorta.
Naunyn-Schmiedeberg's archives of pharmacology 1991;344(1):107-13.
1991: Heijnis J B; Mathy M J; van Zwieten P A
Effects of various calcium antagonists in isolated perfused hearts from diabetic and age-matched control rats.
Journal of cardiovascular pharmacology 1991;17(6):983-9.
1991: Hugtenburg J G; Mathy M J; de Haan N; Beckeringh J J; van Zwieten P A
The influence of calcium antagonists on the adenine nucleotide metabolism in the guinea-pig working heart during ischaemia and reperfusion.
Naunyn-Schmiedeberg's archives of pharmacology 1991;343(5):496-504.
1991: Schwietert H R; Gouw M A; Wilhelm D; Wilffert B; van Zwieten P A
The role of alpha 1-adrenoceptor subtypes in the phasic and tonic responses to phenylephrine in the longitudinal smooth muscle of the rat portal vein.
Naunyn-Schmiedeberg's archives of pharmacology 1991;343(5):463-71.
1991: Blauw G J; van Brummelen P; Doorenbos C J; van der Velde E A; van Zwieten P A
The acute and chronic antihypertensive effects of ketanserin cannot be explained by blockade of vascular serotonin, type 2, receptors or alpha 1-adrenergic receptors.
Clinical pharmacology and therapeutics 1991;49(4):377-84.
1991: Blauw G; Bom A H; van Brummelen P; Camps J; Arndt J W; Verdouw P D; Chang P C; van Zwieten P A; Saxena P R
Effects of 5-hydroxytryptamine on capillary and arteriovenous anastomotic blood flow in the human hand and forearm and in the pig hind leg.
Journal of cardiovascular pharmacology 1991;17(2):316-24.
1990: van Zwieten P A; Blauw G J; van Brummelen P
The role of serotonin in cardiovascular diseases and their treatment.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1990;4(6):1443-7.
1990: Gouw M A; Wilffert B; Van Zwieten P A
Effects of inorganic cations on K(+)-, 5-hydroxytryptamine- and noradrenaline-induced contractions of the isolated rat jugular vein and aorta.
European journal of pharmacology 1990;185(2-3):147-55.
1990: Hugtenburg J G; Van Voorst M J; Van Marle J; Mathy M J; Beckeringh J J; Van Veen H A; Hendriks M G; Van Zwieten P A
The influence of nifedipine and mioflazine on mitochondrial calcium overload in normoxic and ischaemic guinea-pig hearts.
European journal of pharmacology 1990;178(1):71-8.
1990: Gouw M A; Wilffert B; Wermelskirchen D; van Zwieten P A
Ca2+ influx insensitive to organic Ca2+ entry blockers contributes to noradrenaline-induced contractions of the isolated guinea pig aorta.
Pharmacology 1990;40(5):277-87.
1990: van Zwieten P A; Blauw G J; van Brummelen P
The role of 5-hydroxytryptamine and 5-hydroxytryptaminergic mechanisms in hypertension.
British journal of clinical pharmacology 1990;30 Suppl 1():69S-74S.
1990: van Zwieten P A
Pharmacology of antihypertensive agents with multiple actions.
European journal of clinical pharmacology 1990;38 Suppl 2():S77-81.
1990: van Zwieten P A; Blauw G J; van Brummelen P
Pathophysiological and pharmacotherapeutic aspects of serotonin and serotonergic drugs.
Clinical physiology and biochemistry 1990;8 Suppl 3():1-18.
1990: van Zwieten P A
Comparative properties of various beta-blockers, with an outlook to the future.
Clinical physiology and biochemistry 1990;8 Suppl 2():18-27.
1990: Jonkman F A; van Zwieten P A
Aggravation of the severity of the clonidine withdrawal syndrome in conscious rats by beta 2-adrenoceptor antagonists.
Drugs 1990;40 Suppl 4():45-7.
1990: Blauw G J; Doorenbos C J; Bruning T A; van Brummelen P; van Zwieten P A
Antihypertensive treatment with ketanserin shows no evidence of vascular serotonin2-receptor and alpha 1-adrenoceptor blockade.
Drugs 1990;40 Suppl 4():42-4.
1990: van Zwieten P A; Blauw G J; van Brummelen P
Pharmacological profile of antihypertensive drugs with serotonin receptor and alpha-adrenoceptor activity.
Drugs 1990;40 Suppl 4():1-8; discussion 28-30.
1989: van Heiningen P N; Bohnenn V A; van Zwieten P A
Calcium dependency of the angiotensin II-induced vasoconstriction in the rat.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1989;7(6):S158-9.
1989: Jonkman F A; Man P W; Breurkes R; van Zwieten P A
Beta 2-adrenoceptor antagonists intensify clonidine withdrawal syndrome in conscious rats.
Journal of cardiovascular pharmacology 1989;14(6):886-91.
1989: Hugtenburg J G; Mathy M J; Boddeke H W; Beckeringh J J; van Zwieten P A
Differences between negative inotropic and vasodilator effects of calcium antagonists acting on extra- and intracellular calcium movements in rat and guinea-pig cardiac preparations.
Naunyn-Schmiedeberg's archives of pharmacology 1989;340(5):567-75.
1989: Hugtenburg J G; Mathy M J; Beckeringh J J; van Zwieten P A
The differential effect of calcium antagonists on the positive inotropic effects induced by calcium and monensin in cardiac preparations of rats and guinea-pigs.
Naunyn-Schmiedeberg's archives of pharmacology 1989;340(5):558-66.
1989: Boddeke H W; Jap T J; Hugtenburg J G; Heynis J B; Veldsema-Currie R D; Wilffert B; van Zwieten P A
Protective activity of nifedipine and R 58735 upon damage caused by global ischemia in the guinea pig heart-lung preparation.
Basic research in cardiology 1989;84(5):489-98.
1989: van Zwieten P A
Conclusions on the position of urapidil.
The American journal of cardiology 1989;64(7):38D-39D.
1989: van Zwieten P A
Pharmacologic profile of urapidil.
The American journal of cardiology 1989;64(7):1D-6D.
1989: Hugtenburg J G; Mathy M J; Veldsema-Currie R D; Boddeke H W; Beckeringh J J; van Zwieten P A
A comparison of the cardioprotective effects of calcium antagonists from different classes upon ischaemic damage in the guinea-pig working heart.
Naunyn-Schmiedeberg's archives of pharmacology 1989;340(1):126-34.
1989: Hugtenburg J G; Jap T J; Mathy M J; van Heiningen P N; Bohnenn V A; Heijnis J B; Boddeke H W; van Zwieten P A
Cardioprotective effect of trimetazidine and nifedipine in guinea-pig hearts subjected to ischaemia.
Archives internationales de pharmacodynamie et de thérapie 1989;300():186-208.
1989: Blauw G J; van Brummelen P; Chang P C; Vermeij P; van Zwieten P A
Arterial and venous effects of serotonin in the forearm of healthy subjects are not age-related.
Journal of cardiovascular pharmacology 1989;14(1):14-21.
1989: Gouw M A; Wilffert B; van Zwieten P A
Effects of calcium entry blocking agents on 5-hydroxytryptamine- and noradrenaline-induced contractions of rat isolated jugular vein and aorta.
Naunyn-Schmiedeberg's archives of pharmacology 1989;339(5):533-9.
1989: van Zwieten P A
Drugs interacting with alpha adrenoceptors.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1989;3(2):121-33.
1989: Rondas A A; Boddeke H W; Doods H N; Thörig L; van Haeringen N J; van Zwieten P A
Cholinergic receptors in the extraocular rectus muscle of the rabbit.
Ophthalmic research 1989;21(3):162-6.
1989: Gouw M A; Wilffert B; van Zwieten P A
Different sensitivities for four calcium entry blockers of serotonin-, but not K+-induced contractions of isolated jugular vein and aorta of the rat.
Pharmacology 1989;38(5):289-97.
1988: van Heiningen P N; van Zwieten P A
Role of calcium in the vasoconstriction induced by angiotensin II.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1988;6(4):S640-2.
1988: Blauw G J; van Brummelen P; Chang P C; Vermeij P; van Zwieten P A
5HT3 receptor-mediated vasodilation in the human forearm.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1988;6(4):S33-5.
1988: van Zwieten P A
Basic pharmacology of alpha-adrenoceptor antagonists and hybrid drugs.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1988;6(2):S3-11.
1988: van Zwieten P A
Neuro-endocrine changes as new targets in the drug treatment of congestive heart failure.
Pharmacological research communications 1988;20(12):1017-23.
1988: van Heiningen P N; van Zwieten P A
Differential sensitivity to calcium entry blockade of angiotensin II-induced contractions of rat and guinea-pig aorta.
Archives internationales de pharmacodynamie et de thérapie 1988;296():118-30.
1988: Van Zwieten P A
The role of adrenoceptors in circulatory and metabolic regulation.
American heart journal 1988;116(5 Pt 2):1384-92.
1988: Knape J T; van Zwieten P A
Positive chronotropic activity of angiotensin II in the pithed normotensive rat is primarily due to activation of cardiac beta 1-adrenoceptors.
Naunyn-Schmiedeberg's archives of pharmacology 1988;338(2):185-90.
1988: van Zwieten P A
Receptor-mediated inotropic drugs.
European heart journal 1988;9 Suppl H():85-90.
1988: Van Charldorp K J; Davidesko D; Van Zwieten P A
Selectivity of methoctramine for muscarinic receptors in porcine cerebral arteries.
European journal of pharmacology 1988;150(1-2):197-9.
1988: Boddeke E W; Wilffert B; Heynis J B; Hugtenburg J G; Jap W T; Veldsema-Currie R D; Van Zwieten P A
The anti-ischaemic activity of the novel compound, CERM 11956, compared with that of bepridil and nifedipine in isolated guinea-pig hearts.
European journal of pharmacology 1988;149(3):195-203.
1988: Doods H N; Boddeke H W; Kalkman H O; Hoyer D; Mathy M J; van Zwieten P A
Central 5-HT1A receptors and the mechanism of the central hypotensive effect of (+)8-OH-DPAT, DP-5-CT, R28935, and urapidil.
Journal of cardiovascular pharmacology 1988;11(4):432-7.
1988: Korstanje C; Ten Brink E M; Van Zwieten P A
Interaction of calmodulin antagonists with alpha-adrenergic responses in pithed rats and in the perfused hindquarters of the rat.
European journal of pharmacology 1988;148(1):59-67.
1988: Blauw G J; van Brummelen P; Chang P C; Vermeij P; van Zwieten P A
Regional vascular effects of serotonin and ketanserin in young, healthy subjects.
Hypertension 1988;11(3):256-63.
1988: Boddeke H W; Wilffert B; Heynis J B; van Zwieten P A
Investigation of the mechanism of negative inotropic activity of some calcium antagonists.
Journal of cardiovascular pharmacology 1988;11(3):321-5.
1988: Rinner I; Doods H N; van Charldorp K J; Davidesko D; van Zwieten P A
Binding of muscarine receptor antagonists to pig coronary smooth muscle.
Naunyn-Schmiedeberg's archives of pharmacology 1988;337(2):146-50.
1988: Van Zwieten P A
Pharmacology of the alpha 2-adrenoceptor agonist rilmenidine.
The American journal of cardiology 1988;61(7):6D-14D.
1988: Knape J T; van Zwieten P A
Vasoconstrictor activity of vasopressin in the pithed rat.
Archives internationales de pharmacodynamie et de thérapie 1988;291():142-52.
1988: Jap T J; Boddeke H W; van de Haar V; van Zwieten P A
Hemodynamic effects of different calcium antagonists in the heart-lung preparation of the guinea pig.
Pharmacology 1988;36(6):371-9.
1988: Blauw G J; van Brummelen P; Chang P C; Vermeij P; van Zwieten P A
Arterial dilatation and venous constriction induced by serotonin in the elderly.
Drugs 1988;36 Suppl 1():74-7.
1988: Knape J T; van Zwieten P A
Enhanced pressor responses to angiotensin II caused by excessive sodium loading in the pithed rat.
Pharmacology 1988;37(3):165-70.
1988: Boddeke H W; Wilffert B; Hugtenburg J G; Jap T J; Veldsema-Currie R D; van Zwieten P A
Anti-ischaemic activity of various calmodulin antagonists.
Pharmacology 1988;37(4):240-7.
1988: Blauw G J; van Brummelen P; van Zwieten P A
Serotonin induced vasodilatation in the human forearm is antagonized by the selective 5-HT3 receptor antagonist ICS 205-930.
Life sciences 1988;43(18):1441-9.
1988: van Zwieten P A
Compensatory changes of sympathetic tone, the renin-angiotensin-aldosterone system, vasopressin, and ANF as potential therapeutic targets in congestive heart failure.
Zeitschrift für Kardiologie 1988;77 Suppl 5():67-76.
1988: van Zwieten P A
Antihypertensive drugs interacting with alpha- and beta-adrenoceptors. A review of basic pharmacology.
Drugs 1988;35 Suppl 6():6-19.
1988: Blauw G J; van Brummelen P; Bruning T; van Zwieten P A
Local hemodynamic effects of serotonin and ketanserin in healthy subjects: studies in the forearm.
Journal of cardiovascular pharmacology 1988;11 Suppl 1():S41-3.
1987: van Zwieten P A; Timmermans P B; van Heiningen P N
Receptor subtypes involved in the action of calcium antagonists.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1987;5(4):S21-8.
1987: Knape J T; van Zwieten P A
Stimulation of vascular postsynaptic alpha 1-adrenoceptors by noradrenaline, released by angiotensin II in pithed rat preparations.
Archives internationales de pharmacodynamie et de thérapie 1987;290(1):64-76.
1987: Korstanje C; van Zwieten P A
Inhibition of vasoconstriction to cirazoline by calcium-entry blockade after phenoxybenzamine in rat perfused hindquarters.
Naunyn-Schmiedeberg's archives of pharmacology 1987;336(4):409-14.
1987: Boddeke H W; Wilffert B; Heynis J B; van de Haar Keuken V; Jonkman F A; van Zwieten P A
A comparison of the cardiac and vasodilatory effects of some calcium entry blockers in perfused isolated guinea-pig hearts.
Archives internationales de pharmacodynamie et de thérapie 1987;288(2):175-85.
1987: van Brummelen P; Jie K; Timmermans P B; van Zwieten P A
Heterogeneity of vascular alpha-adrenoceptors in man.
Canadian journal of physiology and pharmacology 1987;65(8):1644-8.
1987: Doods H N; Mathy M J; Davidesko D; van Charldorp K J; de Jonge A; van Zwieten P A
Selectivity of muscarinic antagonists in radioligand and in vivo experiments for the putative M1, M2 and M3 receptors.
The Journal of pharmacology and experimental therapeutics 1987;242(1):257-62.
1987: Van Charldorp K J; De Jonge A; Davidesko D; Rinner I; Doods H N; Van Zwieten P A
Coronary constriction induced by vagal stimulation in the isolated rat heart.
European journal of pharmacology 1987;136(1):135-6.
1987: Jie K; Van Brummelen P; Vermey P; Timmermans P B; Van Zwieten P A
Postsynaptic alpha 1- and alpha 2-adrenoceptors in human blood vessels: interactions with exogenous and endogenous catecholamines.
European journal of clinical investigation 1987;17(2):174-81.
1987: Jie K; van Brummelen P; Vermey P; Timmermans P B; van Zwieten P A
Modulation of noradrenaline release by peripheral presynaptic alpha 2-adrenoceptors in humans.
Journal of cardiovascular pharmacology 1987;9(4):407-13.
1987: Jie K; van Brummelen P; Vermey P; Timmermans P B; van Zwieten P A
Influence of calcium entry blockade on alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in the forearm of hypertensive patients.
European journal of clinical pharmacology 1987;32(2):115-20.
1987: van Zwieten P A; Mathy M J; Boddeke H W; Doods H N
Central hypotensive activity of ketanserin in cats.
Journal of cardiovascular pharmacology 1987;10 Suppl 3():S54-8.
1987: van Zwieten P A
Pathophysiological relevance of serotonin.
Journal of cardiovascular pharmacology 1987;10 Suppl 3():S19-25.
1986: Jonkman F A; Boddeke H W; van Zwieten P A
Protective activity of calcium entry blockers against ouabain intoxication in anesthetized guinea pigs.
Journal of cardiovascular pharmacology 1986;8(5):1009-13.
1986: Doods H N; Davidesko D; Mathy M J; Batink H D; de Jonge A; van Zwieten P A
Discrimination by N-ethylmaleimide between the chronotropic and inotropic response to muscarinic receptor stimulation in rat atrium.
Naunyn-Schmiedeberg's archives of pharmacology 1986;333(2):182-5.
1986: Korstanje C; Sprenkels R; Doods H N; Hugtenburg J G; Boddeke E; Batink H D; Thoolen M J; Van Zwieten P A
Characterization of flufylline, fluprofylline, ritanserin, butanserin and R 56413 with respect to in-vivo alpha 1-,alpha 2- and 5-HT2-receptor antagonism and in-vitro affinity for alpha 1-,alpha 2- and 5-HT2-receptors: comparison with ketanserin.
The Journal of pharmacy and pharmacology 1986;38(5):374-9.
1986: van Zwieten P A; Thoolen M J; Jonkman F A; Wilffert B; de Jonge A; Timmermans P B
Central and peripheral effects of S 3341 [(N-dicyclopropylmethyl)-amino-2-oxazoline] in animal models.
Archives internationales de pharmacodynamie et de thérapie 1986;279(1):130-49.
1986: Jie K; van Brummelen P; Vermey P; Timmermans P B; van Zwieten P A
Alpha 1-and alpha 2-adrenoceptor mediated vasoconstriction in the forearm of normotensive and hypertensive subjects.
Journal of cardiovascular pharmacology 1986;8(1):190-6.
1985: van Charldorp K J; de Jonge A; Thoolen M J; van Zwieten P A
Subclassification of muscarinic receptors in the heart, urinary bladder and sympathetic ganglia in the pithed rat. Selectivity of some classical agonists.
Naunyn-Schmiedeberg's archives of pharmacology 1985;331(4):301-6.
1985: Jie K; van Brummelen P; Vermey P; Timmermans P B; van Zwieten P A
Alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in the forearm: differences between normotensive and hypertensive subjects.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1985;3(3):S89-91.
1985: Jie K; van Brummelen P; Vermey P; Timmermans P B; van Zwieten P A
Differences between exogenous and endogenous noradrenaline in the effects on vascular post-synaptic alpha 1- and alpha 2-adrenoceptors in man.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1985;3(3):S145-7.
1985: Korstanje C; Mathy M J; van Charldorp K; de Jonge A; van Zwieten P A
Influence of respiratory acidosis or alkalosis on pressor responses mediated by alpha 1- and alpha 2-adrenoceptors in pithed normotensive rats.
Naunyn-Schmiedeberg's archives of pharmacology 1985;330(3):187-92.
1985: Jonkman F A; Man P W; Thoolen M J; van Zwieten P A
Location of the mechanism of the clonidine withdrawal tachycardia in rats.
The Journal of pharmacy and pharmacology 1985;37(8):580-2.
1985: Doods H N; Kalkman H O; De Jonge A; Thoolen M J; Wilffert B; Timmermans P B; Van Zwieten P A
Differential selectivities of RU 24969 and 8-OH-DPAT for the purported 5-HT1A and 5-HT1B binding sites. Correlation between 5-HT1A affinity and hypotensive activity.
European journal of pharmacology 1985;112(3):363-70.
1985: Thörig L; Hoyng P F; Timmermans P B; van Zwieten P A
M-7 lowers rabbit intraocular pressure.
Ophthalmic research 1985;17(6):362-72.
1985: van Brummelen P; Jie K; Vermey P; Timmermans P B; van Zwieten P A
Vascular alpha-adrenoceptors in man: interactions with adrenaline and noradrenaline.
Clinical science (London, England : 1979) 1985;68 Suppl 10():151s-153s.
1984: Jie K; van Brummelen P; Vermey P; Timmermans P B; van Zwieten P A
Effects of exogenous adrenaline and noradrenaline on vascular postsynaptic alpha 1- and alpha 2-adrenoceptors in man.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1984;2(3):S119-21.
1984: Korstanje C; Doods H N; De Jonge A; Thoolen M J; Wilffert B; Timmermans P B; Van Zwieten P A
Affinity of WY 26703 for central and peripheral alpha 1- and alpha 2-adrenoreceptors in the rat; comparison with yohimbine.
Journal of autonomic pharmacology 1984;4(4):287-93.
1984: de Jonge A; Davidesko D; Mathy M J; Thoolen M J; Wilffert B; van Brummelen P; Timmermans P B; van Zwieten P A
Effect of pithing on the postjunctional sympatho-inhibitory action of captopril in cats.
Naunyn-Schmiedeberg's archives of pharmacology 1984;328(1):30-2.
1984: Korstanje C; Wilffert B; de Jonge A; Thoolen M J; Timmermans P B; van Zwieten P A
Calcium influx-dependent and -independent alpha 1-adrenoceptor-mediated processes of vasoconstriction in vivo do not operate via different alpha 1-adrenoceptor subtypes.
Journal of cardiovascular pharmacology 1984;6(6):1102-8.
1984: Wilffert B; van Heiningen P N; Mathy M J; de Jonge A; Thoolen M J; Timmermans P B; van Zwieten P A
Interactions between the putative calcium entry promotor Bay k 8644 and pressor responses produced by alpha 1- and alpha 2-adrenoceptor agonists in the pithed normotensive rat.
Naunyn-Schmiedeberg's archives of pharmacology 1984;328(1):76-82.
1984: Jonkman F A; Thoolen M J; Wilffert B; de Jonge A; Timmermans P B; Van Zwieten P A
Effect of salbutamol and the PDE-inhibitor RA 642 on the clonidine withdrawal syndrome in rats.
Journal of autonomic pharmacology 1984;4(3):199-206.
1984: Wilffert B; van Heiningen P N; Mathy M J; Batink H D; de Jonge A; Thoolen M J; Timmermans P B; van Zwieten P A
Lack of relationship between intrinsic activity and susceptibility of pressor responses to blockade by nifedipine among the alpha 2-adrenoceptor agonists B-HT 920 and B-HT 958.
Naunyn-Schmiedeberg's archives of pharmacology 1984;327(1):90-2.
1984: Wilffert B; Davidesko D; De Jonge A; Thoolen M J; Timmermans P B; Van Zwieten P A
Interaction between the calcium entry blocker nifedipine with the alpha 1-adrenoreceptor-mediated increase in diastolic pressure elicited by catecholamines.
Journal of autonomic pharmacology 1984;4(2):87-92.
1984: Jie K; van Brummelen P; Vermey P; Timmermans P B; van Zwieten P A
Identification of vascular postsynaptic alpha 1- and alpha 2-adrenoceptors in man.
Circulation research 1984;54(4):447-52.
1984: Timmermans P B; Mathy M J; Wilffert B; Kalkman H O; Smit G; Dijkstra D; Horn A S; Van Zwieten P A
Alpha 1/alpha 2-adrenoceptor agonist selectivity of mono- and dihydroxy-2-N,N-DI-n-propylaminotetralins.
European journal of pharmacology 1984;97(1-2):55-65.
1983: Kalkman H O; Boddeke H W; Timmermans P B; Van Zwieten P A
Calcium-dependency of the pressor responses to selective 5-hydroxytryptamine receptor agonists in pithed rats.
Journal of autonomic pharmacology 1983;3(4):281-6.
1983: Timmermans P B; Mathy M J; Wilffert B; Kalkman H O; Thoolen M J; de Jonge A; van Meel J C; van Zwieten P A
Differential effect of calcium entry blockers on alpha 1-adrenoceptor-mediated vasoconstriction in vivo.
Naunyn-Schmiedeberg's archives of pharmacology 1983;324(4):239-45.
1983: Thörig L; Van Haeringen N J; Timmermans P B; Van Zwieten P A
Peroxidase secretion from rat lacrimal gland cells in vitro: II. The role of calcium in stimulus-secretion coupling.
Experimental eye research 1983;37(5):485-92.
1983: Thörig L; Van Haeringen N J; Timmermans P B; Van Zwieten P A
Peroxidase secretion from rat lacrimal gland cells in vitro. I. Alpha-adrenergic stimulation in the absence of alpha-adrenoceptors.
Experimental eye research 1983;37(5):475-83.
1983: Wilffert B; Davidesko D; De Jonge A; Thoolen M J; Timmermans P B; Van Zwieten P A
Role of ganglionic M-1 and M-2 receptors in the neuronal control of the cardiovascular system of the normotensive rat as determined with pilocarpine.
European journal of pharmacology 1983;95(1-2):109-16.
1983: Wilffert B; Gouw M A; Timmermans P B; van Zwieten P A
Interaction between beta 2-adrenoceptor-mediated vasodilation and alpha 1-adrenoceptor-mediated vasoconstriction in the pithed normotensive rat.
Journal of cardiovascular pharmacology 1983;5(5):829-35.
1983: Wilffert B; Gouw M A; Timmermans P B; van Zwieten P A
Interaction between beta 2-adrenoceptor-mediated vasodilation and alpha 2-adrenoceptor-mediated vasoconstriction in the pithed normotensive rat.
Journal of cardiovascular pharmacology 1983;5(5):822-8.
1983: Wilffert B; Davidesko D; Timmermans P B; van Zwieten P A
Differential role of M-1 and M-2 receptors in sympathetic ganglia of the pithed normotensive rat in alpha adrenoceptor-mediated vasoconstriction.
The Journal of pharmacology and experimental therapeutics 1983;226(3):855-60.
1983: Kalkman H O; Boddeke H W; Doods H N; Timmermans P B; Van Zwieten P A
Hypotensive activity of serotonin receptor agonists in rats is related to their affinity for 5-HT1 receptors.
European journal of pharmacology 1983;91(1):155-6.
1983: Timmermans P B; Wilffert B; Davidesko D; Mathy M J; Dijkstra D; Horn A S; van Zwieten P A
Re-evaluation of the selectivity of 2-N,N-dimethylamino-5,6-dihydroxy-1,2,3, 4-tetrahydronaphthalene (M-7) as an agonist of postjunctional alpha-2 adrenoceptors in the pithed normotensive rat.
The Journal of pharmacology and experimental therapeutics 1983;225(2):407-9.
1983: De Jonge A; Knape J T; Van Meel J C; Kalkman H O; Wilffert B; Thoolen M J; Van Brummelen P; Timmermans P B; Van Zwieten P A
Effect of captopril on sympathetic neurotransmission in pithed normotensive rats.
European journal of pharmacology 1983;88(2-3):231-40.
1983: Timmermans P B; de Jonge A; van Meel J C; Mathy M J; van Zwieten P A
Influence of nifedipine on functional responses in vivo initiated at alpha 2-adrenoceptors.
Journal of cardiovascular pharmacology 1983;5(1):1-11.
1983: Wilffert B; Gouw M A; Timmermans P B; van Zwieten P A
Cardiovascular effects of dopamine and some methylated and fluorinated derivatives in pithed normotensive rats.
Pharmacology 1983;27(3):140-9.
1982: de Jonge A; Knape J T; van Meel J C; Kalkman H O; Wilffert B; Thoolen M J; Timmermanns P B; van Zwieten P A
Effect of converting enzyme inhibition and angiotensin receptor blockade on the vasoconstriction mediated by alpha 1-and alpha 2-adrenoceptor stimulation in pithed normotensive rats.
Naunyn-Schmiedeberg's archives of pharmacology 1982;321(4):309-13.
1982: Wilffert B; Gouw M A; De Jonge A; Timmermans P B; van Zwieten P A
Indications for vascular alpha- and beta-2 adrenoceptors in synapses of the muscarinic pathway in the pithed normotensive rat.
The Journal of pharmacology and experimental therapeutics 1982;223(1):219-23.
1982: Thörig L; van Haeringen N J; Timmermans P B; van Zwieten P A
Alpha-adrenoceptor control of peroxidase secretion from rat lacrimal gland cells in vitro.
Experimental eye research 1982;35(1):29-41.
1981: De Jonge A; Wilffert B; Kalkman H O; Van Meel J C; Thoolen M J; Timmermans P B; Van Zwieten P A
Captopril impairs the vascular smooth muscle contraction mediated by postsynaptic alpha 2-adrenoceptors in the pithed rat.
European journal of pharmacology 1981;74(4):385-6.
1981: Van Meel J C; de Jonge A; Kalkman H O; Wilffert B; Timmermans P B; van Zwieten P A
Organic and inorganic calcium antagonists reduce vasoconstriction in vivo mediated by postsynaptic alpha 2-adrenoceptors.
Naunyn-Schmiedeberg's archives of pharmacology 1981;316(4):288-93.
1981: Van Meel J C; De Jonge A; Kalkman H O; Wilffert B; Timmermans P B; Van Zwieten P A
Vascular smooth muscle contraction initiated by postsynaptic alpha 2-adrenoceptor activation is induced by an influx of extracellular calcium.
European journal of pharmacology 1981;69(2):205-8.

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