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Pieter van Zwieten

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Annemieke A de Groot; Marie-Jeanne Mathy; Pieter A van Zwieten; Stephan L M Peters
Vasodilator effects of nebivolol in a rat model of hypertension and a rabbit model of congestive heart failure.
Pieter A van Zwieten
Do we need new antihypertensive treatments?
Jörn O Streefkerk; Pieter A van Zwieten
Vasopressin receptor antagonists: pharmacological tools and potential therapeutic agents.

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All Publications

2007: Annemieke A de Groot; Marie-Jeanne Mathy; Pieter A van Zwieten; Stephan L M Peters
Vasodilator effects of nebivolol in a rat model of hypertension and a rabbit model of congestive heart failure.
Journal of cardiovascular pharmacology 2007;50(1):56-60.
2007: Pieter A van Zwieten
Do we need new antihypertensive treatments?
Blood pressure 2007;16(5):291-300.
2006: Jörn O Streefkerk; Pieter A van Zwieten
Vasopressin receptor antagonists: pharmacological tools and potential therapeutic agents.
Autonomic & autacoid pharmacology 2006;26(2):141-8.
2005: Pieter A van Zwieten; Csaba Farsang
Combination of antihypertensive drugs from a historical perspective.
Blood pressure 2005;14(2):72-9.
2004: Alexander Nap; Marie-Jeanne Mathy; Jippe C Balt; Martin Pfaffendorf; Pieter A van Zwieten
The evaluation of the N-type channel blocking properties of cilnidipine and other voltage-dependent calcium antagonists.
Fundamental & clinical pharmacology 2004;18(3):309-19.
2004: Alexander Nap; Marie-Jeanne Mathy; Martin Pfaffendorf; Pieter A van Zwieten
Different prejunctional and postjunctional responses to angiotensin II and AT1-receptor inhibition: influence of maturation.
Journal of cardiovascular pharmacology 2004;43(3):432-9.
2004: Jörn O Streefkerk; Jippe C Balt; Gert A van Montfrans; Johannes Van Lieshout; Martin Pfaffendorf; Pieter A van Zwieten
Vasopressin facilitates presynaptic sympathetic nerve activity in humans.
Journal of hypertension 2004;22(3):551-5.
2004: Jörn O Streefkerk; Willem M H Hoogaars; Vincent M Christoffels; Carsten Sand; Martin Pfaffendorf; Stephan L M Peters; Pieter A van Zwieten
Vasopressin-induced vasoconstriction is dependent on MAPKerk1/2 phosphorylation.
Fundamental & clinical pharmacology 2004;18(1):45-50.
2004: Annemieke A de Groot; Pieter A van Zwieten; Stephan L M Peters
Involvement of reactive oxygen species in angiotensin II-induced vasoconstriction.
Journal of cardiovascular pharmacology 2004;43(1):154-9.
2004: Annemieke A de Groot; Marie-Jeanne Mathy; Pieter A van Zwieten; Stephan L M Peters
Antioxidant activity of nebivolol in the rat aorta.
Journal of cardiovascular pharmacology 2004;43(1):148-53.
2004: Alexander Nap; Jippe C Balt; Marie-Jeanne Mathy; Martin Pfaffendorf; Pieter A van Zwieten
Different AT1 receptor subtypes at pre- and postjunctional sites: AT1A versus AT1B receptors.
Journal of cardiovascular pharmacology 2004;43(1):14-20.
2003: Alexander Nap; Charly N W Belterman; Marie-Jeanne Mathy; Jippe C Balt; Martin Pfaffendorf; Pieter A van Zwieten
Impaired neuronal and vascular responses to angiotensin II in a rabbit congestive heart failure model.
Journal of the renin-angiotensin-aldosterone system : JRAAS 2003;4(4):220-7.
2003: Jörn O Streefkerk; Martin Pfaffendorf; Pieter A van Zwieten
Endothelium-dependent, vasopressin-induced contractions in rabbit renal arteries.
Journal of cardiovascular pharmacology 2003;42(6):703-9.
2003: Alexander Nap; Jippe C Balt; Marie-Jeanne Mathy; Pieter A van Zwieten
AT(1)-receptor blockade and sympathetic neurotransmission in cardiovascular disease.
Autonomic & autacoid pharmacology 2003;23(5-6):285-96.
2003: Annemieke A de Groot; Marie-Jeanne Mathy; Pieter A van Zwieten; Stephan L M Peters
Involvement of the beta3 adrenoceptor in nebivolol-induced vasorelaxation in the rat aorta.
Journal of cardiovascular pharmacology 2003;42(2):232-6.
2003: Carsten Sand; Stephan L M Peters; Martin Pfaffendorf; Pieter A van Zwieten
The influence of endogenously generated reactive oxygen species on the inotropic and chronotropic effects of adrenoceptor and ET-receptor stimulation.
Naunyn-Schmiedeberg's archives of pharmacology 2003;367(6):635-9.
2003: Alexander Nap; Marie-Jeanne Mathy; Jippe C Balt; Martin Pfaffendorf; Pieter A van Zwieten
Pre- and postsynaptic inhibitory potencies of the angiotensin AT1 receptor antagonists eprosartan and candesartan.
European journal of pharmacology 2003;469(1-3):117-24.
2003: Carsten Sand; Stephan L M Peters; Martin Pfaffendorf; Pieter A van Zwieten
Effects of hypochlorite and hydrogen peroxide on cardiac autonomic receptors and vascular endothelial function.
Clinical and experimental pharmacology & physiology 2003;30(4):249-53.
2003: Jippe C Balt; Charly N W Belterman; Marie-Jeanne Mathy; Alexander Nap; Antonius Baartscheer; Martin Pfaffendorf; Pieter A van Zwieten
Decreased facilitation by angiotensin II of noradrenergic neurotransmission in isolated mesenteric artery of rabbits with chronic heart failure.
Journal of cardiovascular pharmacology 2003;41(3):356-62.
2003: Jörn O Streefkerk; Martin Pfaffendorf; Pieter A van Zwieten
Vasopressin-induced facilitation of adrenergic responses in the rat mesenteric artery is V1-receptor dependent.
Autonomic & autacoid pharmacology 2003;23(1):35-41.
2003: Jippe C Balt; Marie-Jeanne Mathy; Martin Pfaffendorf; Pieter A van Zwieten
Sympatho-inhibitory actions of irbesartan in pithed spontaneously hypertensive and Wistar-Kyoto rats.
Fundamental & clinical pharmacology 2003;17(1):83-91.
2002: Jörn O Streefkerk; Annemieke A de Groot; Martin Pfaffendorf; Pieter A van Zwieten
Influence of the nature of pre-contraction on the responses to commonly employed vasodilator agents in rat-isolated aortic rings.
Fundamental & clinical pharmacology 2002;16(6):485-94.
2002: Jippe C Balt; Marie-Jeanne Mathy; Alexander Nap; Martin Pfaffendorf; Pieter A van Zwieten
Involvement of the AT(2)-receptor in angiotensin II-induced facilitation of sympathetic neurotransmission.
Journal of the renin-angiotensin-aldosterone system : JRAAS 2002;3(3):181-7.
2002: Alexander Nap; Jippe C Balt; Martin Pfaffendorf; Pieter A van Zwieten
Sympatholytic properties of several AT1-receptor antagonists in the isolated rabbit thoracic aorta.
Journal of hypertension 2002;20(9):1821-8.
2002: Stephan L M Peters; Carsten Sand; Martin C Michel; Martin Pfaffendorf; Pieter A van Zwieten
A mitogen-activated protein kinase is involved in the inotropic but not chronotropic actions of adrenoceptor agonists and endothelin-1.
Naunyn-Schmiedeberg's archives of pharmacology 2002;366(2):189-91.
2002: Jippe C Balt; Marie-Jeanne Mathy; Alexander Nap; Martin Pfaffendorf; Pieter A van Zwieten
Prejunctional and postjunctional inhibitory actions of eprosartan and candesartan in the isolated rabbit mesenteric artery.
Journal of cardiovascular pharmacology 2002;40(1):50-7.
2002: Jippe C Balt; Marie-Jeanne Mathy; Martin Pfaffendorf; Pieter A van Zwieten
Sympatho-inhibitory properties of various AT1 receptor antagonists.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 2002;20(5):S3-11.
2002: Pieter A van Zwieten; Stevo Julius
AT1 blockers: are there alternative pathways reducing cardiovascular risk? Introduction.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 2002;20(5):S1.
2002: Jörn O Streefkerk; Marie-Jeanne Mathy; Martin Pfaffendorf; Pieter A van Zwieten
Vasopressin-induced presynaptic facilitation of sympathetic neurotransmission in the pithed rat.
Journal of hypertension 2002;20(6):1175-80.
2002: Carsten Sand; Stephan L M Peters; Marie-Jeanne Mathy; Martin Pfaffendorf; Pieter A van Zwieten
The effects of hypochlorite-induced oxidative stress on presynaptic M2-receptors at sympathetic nerve endings in the rat tail artery.
Autonomic & autacoid pharmacology 2002;22(2):127-32.
2001: Jippe C Balt; Marie-Jeanne Mathy; Martin Pfaffendorf; Pieter A van Zwieten
Inhibition of facilitation of sympathetic neurotransmission and angiotensin II-induced pressor effects in the pithed rat: comparison between valsartan, candesartan, eprosartan and embusartan.
Journal of hypertension 2001;19(12):2241-50.
2001: Alexander Nap; Martin Pfaffendorf; Pieter A van Zwieten
Characterisation of a modified approach to the study of sympathetic neurotransmission and its presynaptic modulation in the isolated rabbit thoracic aorta.
Journal of pharmacological and toxicological methods 2001;46(3):145-51.
2001: Carsten Sand; Stephan L M Peters; Martin Pfaffendorf; Pieter A van Zwieten
Oxidative stress impairs the haemodynamic activity of cardiovascular agents with antioxidant properties.
Naunyn-Schmiedeberg's archives of pharmacology 2001;364(5):454-61.
2001: Stephan L M Peters; Carsten Sand; H D Batinik; Martin Pfaffendorf; Pieter A van Zwieten
Reactive oxygen species potentiate the negative inotropic effect of cardiac M2-muscarinic receptor stimulation.
Naunyn-Schmiedeberg's archives of pharmacology 2001;364(2):166-71.
2001: Jippe C Balt; Marie-Jeanne Mathy; Alexander Nap; Martin Pfaffendorf; Pieter A van Zwieten
Effect of the AT1-receptor antagonists losartan, irbesartan, and telmisartan on angiotensin II-induced facilitation of sympathetic neurotransmission in the rat mesenteric artery.
Journal of cardiovascular pharmacology 2001;38(1):141-8.
2001: Q Li; Martin Pfaffendorf; Pieter A van Zwieten
Different types of antagonism by losartan and irbesartan on the effects of angiotensin II and its degradation products in rabbit arteries.
Fundamental & clinical pharmacology 2001;15(2):143-50.
2001: Jippe C Balt; Marie-Jeanne Mathy; Martin Pfaffendorf; Pieter A van Zwieten
Inhibition of angiotensin II-induced facilitation of sympathetic neurotransmission in the pithed rat: a comparison between losartan, irbesartan, telmisartan, and captopril.
Journal of hypertension 2001;19(3):465-73.
2001: Pieter A van Zwieten
Centrally acting imidazoline I1-receptor agonists: do they have a place in the management of hypertension?
American journal of cardiovascular drugs : drugs, devices, and other interventions 2001;1(5):321-6.
2001: R van der Lee; Martin Pfaffendorf; R P Koopmans; Johannes Van Lieshout; Gert A van Montfrans; Pieter A van Zwieten
Comparison of the time courses and potencies of the vasodilator effects of nifedipine and felodipine in the human forearm.
Blood pressure 2001;10(4):217-22.
2000: FJ Heijenbrok; Marie-Jeanne Mathy; Martin Pfaffendorf; Pieter A van Zwieten
The influence of chronic inhibition of nitric oxide synthesis on contractile and relaxant properties of rat carotid and mesenteric arteries.
Naunyn-Schmiedeberg's archives of pharmacology 2000;362(6):504-11.
2000: R van der Lee; Martin Pfaffendorf; Pieter A van Zwieten
The differential time courses of the vasodilator effects of various 1,4-dihydropyridines in isolated human small arteries are correlated to their lipophilicity.
Journal of hypertension 2000;18(11):1677-82.
2000: FJ Heijenbrok; Marie-Jeanne Mathy; Martin Pfaffendorf; Pieter A van Zwieten
Beta-adrenergic responses are significantly enhanced in rat carotid artery with intimal hyperplasia.
Naunyn-Schmiedeberg's archives of pharmacology 2000;362(3):276-83.
2000: Martin Pfaffendorf; HD Batink; Christian Tränkle; Klaus Mohr; Pieter A van Zwieten
Probing the selectivity of allosteric modulators of muscarinic receptors at other G-protein-coupled receptors.
Journal of autonomic pharmacology 2000;20(1):55-62.
2000: Martin Pfaffendorf; Marie-Jeanne Mathy; R van der Lee; Pieter A van Zwieten
Evidence for a sympatholytic effect of mibefradil in the pithed rat preparation.
Journal of hypertension 2000;18(2):203-7.
2000: Stephan L M Peters; Marie-Jeanne Mathy; Martin Pfaffendorf; Pieter A van Zwieten
Reactive oxygen species-induced aortic vasoconstriction and deterioration of functional integrity.
Naunyn-Schmiedeberg's archives of pharmacology 2000;361(2):127-33.
2000: R van der Lee; Martin Pfaffendorf; Jo De Mey; Pieter A van Zwieten
Inhibitory effect of mibefradil on contractions induced by sympathetic neurotransmitter release in the rat tail artery.
Naunyn-Schmiedeberg's archives of pharmacology 2000;361(1):74-9.
1999: Pieter A van Zwieten
Beneficial interactions between pharmacological, pathophysiological and hypertension research.
Journal of hypertension 1999;17(12 Pt 2):1787-97.
1999: Pieter A van Zwieten
The renaissance of centrally acting antihypertensive drugs.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1999;17(3):S15-21.
1999: Pieter A van Zwieten; Stevo Julius
The importance of the sympathetic nervous system in hypertension. Introduction.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1999;17(3):S1.
1999: Pieter A van Zwieten
Centrally acting antihypertensive drugs. Present and future.
Clinical and experimental hypertension (New York, N.Y. : 1993) 1999;21(5-6):859-73.
1999: Pieter A van Zwieten; Stephan L M Peters
Central I1-imidazoline receptors as targets of centrally acting antihypertensive drugs. Clinical pharmacology of moxonidine and rilmenidine.
Annals of the New York Academy of Sciences 1999;881():420-9.
1999: J Baan; PC Chang; Pieter Vermeij; Martin Pfaffendorf; Pieter A van Zwieten
Effects of sodium depletion on the role of AT1- and alpha-adrenergic receptors in the regulation of forearm vascular tone in humans.
Journal of hypertension 1999;17(2):229-35.
1999: Pieter A van Zwieten; L Hansson
Calcium antagonists and safety: the turning of the tide.
Blood pressure 1999;8(1):5-8.
1999: R van der Lee; Martin Pfaffendorf; Pieter A van Zwieten
Comparative effects of mibefradil and other calcium antagonists on resistance arteries of different end organs.
Fundamental & clinical pharmacology 1999;13(2):198-203.
1999: Pieter A van Zwieten
Diabetes and hypertension: experimental models for pharmacological studies.
Clinical and experimental hypertension (New York, N.Y. : 1993) 1999;21(1-2):1-16.
1999: J Baan; Martin Pfaffendorf; A C van der Wal; PC Chang; Pieter A van Zwieten
Influence of losartan and nicardipine on the contractile responses of human subcutaneous arteries and veins to angiotensin II.
Fundamental & clinical pharmacology 1999;13(1):43-9.
1998: Pieter A van Zwieten
Introduction: the role of calcium antagonists.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1998;16(6):S1-2.
1998: J Baan; PC Chang; Pieter Vermeij; Martin Pfaffendorf; Pieter A van Zwieten
Effects of angiotensin II and losartan in the forearm of patients with essential hypertension.
Journal of hypertension 1998;16(9):1299-305.
1998: Q Li; J Zhang; J F Loro; Martin Pfaffendorf; Pieter A van Zwieten
Bradykinin B2-receptor-mediated positive chronotropic effect of bradykinin in isolated rat atria.
Journal of cardiovascular pharmacology 1998;32(3):452-6.
1998: Stephan L M Peters; HD Batink; Martin C Michel; Martin Pfaffendorf; Pieter A van Zwieten
Possible mechanism of the negative inotropic effect of alpha1-adrenoceptor agonists in rat isolated left atria after exposure to free radicals.
British journal of pharmacology 1998;123(5):952-8.
1998: FJ Heijenbrok; A C van der Wal; Martin Pfaffendorf; Pieter A van Zwieten
Morphologic and functional consequences of intimal hyperplasia in the rat carotid artery.
Naunyn-Schmiedeberg's archives of pharmacology 1998;357(2):133-42.
1998: Pieter A van Zwieten
The pharmacological properties of lipophilic calcium antagonists.
Blood pressure. Supplement 1998;2():5-9.
1998: R van der Lee; K L Kam; Martin Pfaffendorf; Pieter A van Zwieten
Differential time course of the vasodilator action of various calcium antagonists.
Fundamental & clinical pharmacology 1998;12(6):607-12.
1998: Pieter A van Zwieten
Pharmacological profile of barnidipine: a single optical isomer dihydropyridine calcium antagonist.
Blood pressure. Supplement 1998;1():5-8.
1998: J Baan; PC Chang; Pieter Vermeij; Martin Pfaffendorf; Pieter A van Zwieten
Venoconstriction by angiotensin II in the human forearm is inhibited by losartan but not by nicardipine.
Journal of cardiovascular pharmacology 1998;31(1):50-5.
1997: J Baan; PC Chang; Pieter Vermeij; Martin Pfaffendorf; Pieter A van Zwieten
Influence of indomethacin and L-NMMA on vascular tone and angiotensin II-induced vasoconstriction in the human forearm.
Blood pressure 1997;6(5):279-85.
1997: J Zwaveling; Martin Pfaffendorf; Pieter A van Zwieten
The influence of hyperthyroidism on vasoconstrictor and vasodilator responses in isolated coronary and renal resistance arteries.
Pharmacology 1997;55(3):117-25.
1997: Martin Pfaffendorf; T A Bruning; H D Batnik; Pieter A van Zwieten
The interaction between methylene blue and the cholinergic system.
British journal of pharmacology 1997;122(1):95-8.
1997: BC Hüsken; Allard C van der Wal; Peter Teeling; Marie-Jeanne Mathy; M J Mertens; A J Pul; Martin Pfaffendorf; Pieter A van Zwieten
Heterogeneity in morphological characteristics of coronary arteries and aortae in various models of hypertension.
Blood pressure 1997;6(4):242-9.
1997: Q Li; Marike Feenstra; Martin Pfaffendorf; León Eijsman; Pieter A van Zwieten
Comparative vasoconstrictor effects of angiotensin II, III, and IV in human isolated saphenous vein.
Journal of cardiovascular pharmacology 1997;29(4):451-6.
1997: Pieter A van Zwieten; L Hansson; Murray Epstein
Slowly acting calcium antagonists and their merits.
Blood pressure 1997;6(2):78-80.
1997: Stephan L M Peters; Martin Pfaffendorf; Pieter A van Zwieten
The influence of oxidative stress on various inotropic responses in isolated rat left atria.
Naunyn-Schmiedeberg's archives of pharmacology 1997;355(3):390-7.
1997: Pieter A van Zwieten
Central imidazoline (I1) receptors as targets of centrally acting antihypertensives: moxonidine and rilmenidine.
Journal of hypertension 1997;15(2):117-25.
1997: Pieter A van Zwieten
Endothelial dysfunction in hypertension. A critical evaluation.
Blood pressure. Supplement 1997;2():67-70.
1997: J Zwaveling; Martin Pfaffendorf; Pieter A van Zwieten
The direct effects of thyroid hormones on rat mesenteric resistance arteries.
Fundamental & clinical pharmacology 1997;11(1):41-6.
1997: Pieter A van Zwieten
Recent changes in the treatment of congestive heart failure. Introduction.
Cardiology 1997;88 Suppl 2():1.
1997: O H Beenen; HD Batink; Martin Pfaffendorf; Pieter A van Zwieten
Beta-andrenoceptors in the hearts of diabetic-hypertensive rats: radioligand binding and functional experiments.
Blood pressure 1997;6(1):44-51.
1997: Pieter A van Zwieten
Current and newer approaches in the drug treatment of congestive heart failure.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1997;10(6):693-702.
1997: E A Dubois; G Aernout Somsen; Jan C van den Bos; Anton G M Janssen; HD Batink; GJ Boer; EA van Royen; Martin Pfaffendorf; Pieter A van Zwieten
Development of radioligands for the imaging of cardiac beta-adrenoceptors using SPECT. Part II: Pharmacological characterization in vitro and in vivo of new 123I-labeled beta-adrenoceptor antagonists.
Nuclear medicine and biology 1997;24(1):9-13.
1997: Jan C van den Bos; PA van Doremalen; E A Dubois; G Aernout Somsen; Jef A J M Vekemans; Anton G M Janssen; GJ Boer; Martin Pfaffendorf; EA van Royen; Pieter A van Zwieten
Development of radioligands for the imaging of cardiac beta-adrenoceptors using SPECT. Part I: Asymmetric synthesis and structural characterization of five new iodine-containing beta-adrenoceptor antagonist derivatives.
Nuclear medicine and biology 1997;24(1):1-7.
1997: Pieter A van Zwieten
Centrally acting antihypertensives: a renaissance of interest. Mechanisms and haemodynamics.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1997;15(1):S3-8.
1997: BC Hüsken; Martin Pfaffendorf; Pieter A van Zwieten
Contribution of ATP-sensitive potassium channels to beta-adrenoceptor-mediated responses.
Naunyn-Schmiedeberg's archives of pharmacology 1997;355(1):97-102.
1997: BC Hüsken; Martin Pfaffendorf; Pieter A van Zwieten
ATP-sensitive potassium channels in isolated rat aorta during physiologic, hypoxic, and low-glucose conditions.
Journal of cardiovascular pharmacology 1997;29(1):130-5.
1996: J Zwaveling; HD Batink; J de Jong; E A Winkler Prins; Martin Pfaffendorf; Pieter A van Zwieten
Thyroid hormone modulates inotropic responses, alpha-adrenoceptor density and catecholamine concentrations in the rat heart.
Naunyn-Schmiedeberg's archives of pharmacology 1996;354(6):755-64.
1996: T A Bruning; PC Chang; M J Kemme; P Vermeij; Martin Pfaffendorf; Pieter A van Zwieten
Comparison of cholinergic vasodilator responses to acetylcholine and methacholine in the human forearm.
Blood pressure 1996;5(6):333-41.
1996: J Baan; PC Chang; P Vermeij; Martin Pfaffendorf; Pieter A van Zwieten
Effects of losartan on vasoconstrictor responses to angiotensin II in the forearm vascular bed of healthy volunteers.
Cardiovascular research 1996;32(5):973-9.
1996: Pieter A van Zwieten
Clinical pharmacology of calcium antagonists as antihypertensive and anti-anginal drugs.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1996;14(3):S3-9.
1996: M B Vroom; Harry B van Wezel; R B vd Brink; R vd Lee; León Eijsman; Cees A Visser; Pieter A van Zwieten
Effects of dobutamine and enoximone on transmitral and pulmonary venous flow characteristics in patients with left ventricular dysfunction after coronary artery bypass grafting.
Journal of cardiothoracic and vascular anesthesia 1996;10(6):756-63.
1996: O H Beenen; Martin Pfaffendorf; Pieter A van Zwieten
Influence of the low thyroid state in diabetes mellitus on cardiac function and inotropic responsiveness to alpha 1-adrenoceptor stimulation: comparison with the role of hypothyroidism alone.
Journal of cardiovascular pharmacology 1996;28(4):553-7.
1996: O H Beenen; M J Mathy; Martin Pfaffendorf; Pieter A van Zwieten
Vascular responsiveness in isolated perfused kidneys of diabetic hypertensive rats.
Journal of hypertension 1996;14(9):1125-30.
1996: Pieter A van Zwieten
The role of public health authorities, scientific societies and the pharmaceutical industry in planning and conducting intervention trials.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1996;14(2):S135-9; discussion S139-40.
1996: E A Dubois; Jan C van den Bos; T Doornbos; PA van Doremalen; G Aernout Somsen; Jef A J M Vekemans; Anton G M Janssen; HD Batink; G J Boer; Martin Pfaffendorf; EA van Royen; Pieter A van Zwieten
Synthesis and in vitro and in vivo characteristics of an iodinated analogue of the beta-adrenoceptor antagonist carazolol.
Journal of medicinal chemistry 1996;39(17):3256-62.
1996: Q Li; J Zhang; Martin Pfaffendorf; Pieter A van Zwieten
Direct positive chronotropic effects of angiotensin II and angiotensin III in pithed rats and in rat isolated atria.
British journal of pharmacology 1996;118(7):1653-8.
1996: E A Dubois; K L Kam; G Aernout Somsen; G J Boer; Kora de Bruin; HD Batink; Martin Pfaffendorf; EA van Royen; Pieter A van Zwieten
Cardiac iodine-123 metaiodobenzylguanidine uptake in animals with diabetes mellitus and/or hypertension.
European journal of nuclear medicine 1996;23(8):901-8.
1996: O H Beenen; M J Mathy; Martin Pfaffendorf; Pieter A van Zwieten
Influence of nifedipine on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed diabetic hypertensive rats.
Journal of hypertension 1996;14(7):847-53.
1996: Pieter A van Zwieten
Modulation of sympathetic outflow by centrally acting antihypertensive drugs.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1996;10 Suppl 1():283-9.
1996: E A Dubois; G Aernout Somsen; Jan C van den Bos; Anton G M Janssen; G J Boer; HD Batink; EA van Royen; Martin Pfaffendorf; Pieter A van Zwieten
Pharmacologic characterization in vitro and in vivo of iodine 123-labeled derivatives of the beta-adrenoceptor antagonist CGP12177, designed for the imaging of cardiac beta-receptors.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 1996;3(3):242-52.
1996: J G van der Stroom; Harry B van Wezel; Isabelle Vergroesen; Jasper E Kal; Jacques J Koolen; J P Dijkhuis; A Swaan; M Porsius; H A Kleinjans; Pieter A van Zwieten
Comparison of the effects of urapidil and sodium nitroprusside on haemodynamic state, myocardial metabolism and function in patients during coronary artery surgery.
British journal of anaesthesia 1996;76(5):645-51.
1996: J Zwaveling; E A Prins; MA Maas; Martin Pfaffendorf; Pieter A van Zwieten
The influence of hyperthyroidism on pharmacologically induced contractions of isolated resistance arteries.
European journal of pharmacology 1996;300(1-2):91-7.
1996: Pieter A van Zwieten
New central mediators as targets of centrally acting antihypertensive drugs.
Clinical and experimental hypertension (New York, N.Y. : 1993) 1996;18(3-4):291-303.
1996: J Zwaveling; E A Winkler Prins; Martin Pfaffendorf; Pieter A van Zwieten
The influence of hyperthyroidism on beta-adrenoceptor-mediated relaxation of isolated small mesenteric arteries.
Naunyn-Schmiedeberg's archives of pharmacology 1996;353(4):438-44.
1996: Pieter A van Zwieten; K L Kam; A J Pijl; M G Hendriks; O H Beenen; Martin Pfaffendorf
Hypertensive diabetic rats in pharmacological studies.
Pharmacological research : the official journal of the Italian Pharmacological Society 1996;33(2):95-105.
1996: Pieter A van Zwieten; M Pfaffendorf; G Mancia
Attempts to improve the selectivity of calcium antagonistic drugs.
Blood pressure. Supplement 1996;5():7-9.
1996: Pieter A van Zwieten
From alpha and beta to I1: an overview of sympathetic receptors involved in blood pressure control targets for drug treatment.
Journal of cardiovascular pharmacology 1996;27 Suppl 3():S5-10.
1996: K L Kam; Martin Pfaffendorf; Pieter A van Zwieten
Pharmacodynamic behaviour of isolated resistance vessels obtained from hypertensive-diabetic rats.
Fundamental & clinical pharmacology 1996;10(4):329-36.
1996: G Aernout Somsen; E A Dubois; K Brandsma; J de Jong; Pol A van der Wouw; HD Batink; EA van Royen; Kong I Lie; Pieter A van Zwieten
Cardiac sympathetic neuronal function in left ventricular volume and pressure overload.
Cardiovascular research 1996;31(1):132-8.
1996: O H Beenen; M J Mathy; Martin Pfaffendorf; Pieter A van Zwieten
Opposite influences of hypertension and diabetes mellitus on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed rats.
Blood pressure 1996;5(1):57-63.
1996: M B Vroom; Martin Pfaffendorf; Harry B van Wezel; Pieter A van Zwieten
Effect of phosphodiesterase inhibitors on human arteries in vitro.
British journal of anaesthesia 1996;76(1):122-9.
1996: K L Kam; M G Hendriks; A J Pijl; J van Marle; H A van Veen; Martin Pfaffendorf; Pieter A van Zwieten
Contractile responses to various stimuli in isolated resistance vessels from simultaneously hypertensive and streptozotocin-diabetic rats.
Journal of cardiovascular pharmacology 1996;27(1):167-75.
1995: B C Hüsken; M B Vroom; E J Timmenga; Martin Pfaffendorf; Pieter A van Zwieten
Relaxant effect of levcromakalim in isolated human small subcutaneous arteries.
European journal of pharmacology 1995;287(3):313-6.
1995: M J Mertens; HD Batink; M J Mathy; Martin Pfaffendorf; Pieter A van Zwieten
Reduced muscarinic cholinoceptor density and sensitivity in various models of experimental cardiac hypertrophy.
Journal of autonomic pharmacology 1995;15(6):465-74.
1995: Q Li; L Zhang; Martin Pfaffendorf; Pieter A van Zwieten
Comparative effects of angiotensin II and its degradation products angiotensin III and angiotensin IV in rat aorta.
British journal of pharmacology 1995;116(7):2963-70.
1995: O H Beenen; Martin Pfaffendorf; Pieter A van Zwieten
Contractile responses to various inotropic agents in isolated hearts obtained from hypertensive diabetic rats.
Blood pressure 1995;4(6):372-8.
1995: M Vischjager; Thomas M van Gulik; Martin Pfaffendorf; Pieter A van Zwieten; J Van Marle; J G Kromhout; P J Klopper; Michael J Jacobs
Morphology and function of dog arterial grafts preserved in UW-solution.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 1995;10(4):431-9.
1995: Pieter A van Zwieten; M G Hendriks; Martin Pfaffendorf; T A Bruning; PC Chang
The parasympathetic system and its muscarinic receptors in hypertensive disease.
Journal of hypertension 1995;13(10):1079-90.
1995: M J Kemme; T A Bruning; PC Chang; Pieter A van Zwieten
Cholinergic receptor-mediated responses in the arteriolar and venous vascular beds of the human forearm.
Blood pressure 1995;4(5):293-9.
1995: T A Bruning; PC Chang; M G Hendriks; P Vermeij; Martin Pfaffendorf; Pieter A van Zwieten
In vivo characterization of muscarinic receptor subtypes that mediate vasodilatation in patients with essential hypertension.
Hypertension 1995;26(1):70-7.
1995: Pieter A van Zwieten; M Safar; S Laurent; Martin Pfaffendorf; M G Hendriks; T A Bruning
New insights into the role of endothelial dysfunction in hypertension.
Journal of hypertension 1995;13(7):713-6.
1995: Karel T Koch; D R Düren; Pieter A van Zwieten
Long-term antiarrhythmic efficacy and safety of d-sotalol in patients with ventricular tachycardia and a low ejection fraction.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1995;9(3):437-43.
1995: M B Vroom; Harry B van Wezel; Cees A Visser; León Eijsman; Pieter A van Zwieten
Hemodynamic effects of the novel selective cAMP-phosphodiesterase III inhibitor R 80122 in anesthetized patients with moderate left ventricular dysfunction before coronary artery bypass grafting.
Journal of cardiothoracic and vascular anesthesia 1995;9(3):272-7.
1995: A J Pijl; Harry B van Wezel; Jacques J Koolen; J J Piek; K Koch; A Swaan; GK David; Cees A Visser; Pieter A van Zwieten
The negative inotropic and chronotropic effects of intravenous R 56865 during percutaneous transluminal coronary angioplasty.
British journal of clinical pharmacology 1995;39(5):531-5.
1995: J Zhang; Martin Pfaffendorf; Pieter A van Zwieten
Hemodynamic effects of angiotensin II and the influence of angiotensin receptor antagonists in pithed rabbits.
Journal of cardiovascular pharmacology 1995;25(5):724-31.
1995: M J Mertens; Martin Pfaffendorf; Pieter A van Zwieten
Sensitivity of cardiac tissues with moderate and advanced hypertrophy to calcium ions.
General pharmacology 1995;26(2):399-406.
1995: Pieter A van Zwieten; Henri Doods
Muscarinic receptors and drugs in cardiovascular medicine.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1995;9(1):159-67.
1995: Pieter A van Zwieten
Pharmacological backgrounds of the drug treatment of hypertension in the elderly.
Blood pressure. Supplement 1995;3():15-20.
1995: J Zhang; Martin Pfaffendorf; J S Zhang; Pieter A van Zwieten
Influence of the vascular endothelium on angiotensin II-induced contractions in rabbit renal artery.
Fundamental & clinical pharmacology 1995;9(1):25-9.
1995: R van den Ende; I Guttmann; E Scheufler; Martin Pfaffendorf; Pieter A van Zwieten
Effect of Na+ reduction and monensin on ion content and contractile response in normoxic and ischaemic reperfused rat hearts.
Fundamental & clinical pharmacology 1995;9(2):161-8.
1995: N M van Es; T A Bruning; J Camps; PC Chang; Gerard J Blauw; M D Ferrari; P R Saxena; Pieter A van Zwieten
Assessment of peripheral vascular effects of antimigraine drugs in humans.
Cephalalgia : an international journal of headache 1995;15(4):288-91.
1994: A J Pijl; Allard C van der Wal; M J Mathy; K L Kam; M G Hendriks; Martin Pfaffendorf; Pieter A van Zwieten
Streptozotocin-induced diabetes mellitus in spontaneously hypertensive rats: a pathophysiological model for the combined effects of hypertension and diabetes.
Journal of pharmacological and toxicological methods 1994;32(4):225-33.
1994: Pieter A van Zwieten; J P Chalmers
Different types of centrally acting antihypertensives and their targets in the central nervous system.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1994;8(6):787-99.
1994: B C Hüsken; M G Hendriks; Martin Pfaffendorf; Pieter A van Zwieten
Effects of aging and hypertension on the reactivity of isolated conduit and resistance vessels.
Microvascular research 1994;48(3):303-15.
1994: K L Kam; Martin Pfaffendorf; Pieter A van Zwieten
Drug-induced endothelium-dependent and -independent relaxations in isolated resistance vessels taken from simultaneously hypertensive and streptozotocin-diabetic rats.
Blood pressure 1994;3(6):418-27.
1994: J Zhang; J C Van Meel; Martin Pfaffendorf; J Zhang; Pieter A van Zwieten
Endothelium-dependent, nitric oxide-mediated inhibition of angiotensin II-induced contractions in rabbit aorta.
European journal of pharmacology 1994;262(3):247-53.
1994: Pieter A van Zwieten
Amlodipine: an overview of its pharmacodynamic and pharmacokinetic properties.
Clinical cardiology 1994;17(9 Suppl 3):III3-6.
1994: T A Bruning; PC Chang; Gerard J Blauw; P Vermeij; Pieter A van Zwieten
Interactions between serotonin and endogenous and exogenous noradrenaline in the human forearm.
Blood pressure 1994;3(5):309-18.
1994: T A Bruning; Pieter A van Zwieten; Gerard J Blauw; PC Chang
No functional involvement of 5-hydroxytryptamine1A receptors in nitric oxide-dependent dilatation caused by serotonin in the human forearm vascular bed.
Journal of cardiovascular pharmacology 1994;24(3):454-61.
1994: B C Hüsken; M J Mertens; Martin Pfaffendorf; Pieter A van Zwieten
The influence of coarctation hypertension on the pharmacodynamic behaviour of rat isolated conduit vessels.
Blood pressure 1994;3(4):255-9.
1994: J Zhang; Martin Pfaffendorf; Pieter A van Zwieten
Effect of various angiotensin receptor antagonists on cardiovascular responses to angiotensin II in pithed rats.
Journal of cardiovascular pharmacology 1994;24(1):108-13.
1994: A J Pijl; M G Hendriks; K L Kam; M Paffendorf; Pieter A van Zwieten
Effects of R 56865 on postischemic ventricular function in isolated rat working heart preparations obtained from healthy, diabetic and hypertensive animals.
Naunyn-Schmiedeberg's archives of pharmacology 1994;349(6):619-26.
1994: J S Zhang; J C Van Meel; Martin Pfaffendorf; Pieter A van Zwieten
Different types of angiotensin II receptor antagonism induced by BIBS 222 in the rat portal vein and rabbit aorta; the influence of receptor reserve.
The Journal of pharmacology and experimental therapeutics 1994;269(2):509-14.
1994: T A Bruning; M G Hendriks; PC Chang; E A Kuypers; Pieter A van Zwieten
In vivo characterization of vasodilating muscarinic-receptor subtypes in humans.
Circulation research 1994;74(5):912-9.
1994: J S Zhang; J C van Meel; Martin Pfaffendorf; Pieter A van Zwieten
Inhibitory effect of dithiothreitol on angiotensin II-induced contractions mediated by AT1-receptors in rat portal vein and rabbit aorta.
Naunyn-Schmiedeberg's archives of pharmacology 1994;349(5):538-42.
1994: J S Zhang; J C Van Meel; Martin Pfaffendorf; J Zhang; Pieter A van Zwieten
Calcium dependency of the AT1-receptor mediated effects in the rat portal vein: influence of calcium antagonists.
Naunyn-Schmiedeberg's archives of pharmacology 1994;349(4):437-42.
1994: A J Pijl; M G Hendriks; K L Kam; Martin Pfaffendorf; Pieter A van Zwieten
Antiischemic effects of nifedipine in isolated working heart preparations of healthy, diabetic, and hypertensive rats.
Journal of cardiovascular pharmacology 1994;23(3):379-86.
1994: J Zhang; Martin Pfaffendorf; J S Zhang; Pieter A van Zwieten
A non-competitive type of angiotensin-receptor antagonism by losartan in renal artery preparations.
European journal of pharmacology 1994;252(3):337-40.
1994: R van den Ende; HD Batink; M C Michel; Pieter A van Zwieten
Influence of ischaemia and reperfusion on cardiac signal transduction. G protein content, adenylyl cyclase activity, cyclic AMP content, and forskolin and dibutyryl cyclic AMP-induced inotropy in the rat Langendorff heart.
Fundamental & clinical pharmacology 1994;8(5):408-16.
1994: J G Van der Stroom; Harry B van Wezel; J J Koolen; C A Visser; Pieter A van Zwieten
Comparison of the effects of urapidil and nitroprusside on hemodynamics and myocardial function in hypertension following cardiac surgery.
Blood pressure. Supplement 1994;4():31-8.
1994: Pieter A van Zwieten; T A Bruning
Comparison of the hemodynamic effects of urapidil and flesinoxan in healthy volunteers.
Blood pressure. Supplement 1994;4():19-24.
1993: M G Hendriks; Martin Pfaffendorf; Pieter A van Zwieten
The effect of muscarinic receptor alkylation on endothelium-dependent vasodilation in SHR.
Blood pressure 1993;2(4):332-8.
1993: Pieter A van Zwieten; Martin Pfaffendorf
Pharmacology of the dihydropyridine calcium antagonists: relationship between lipophilicity and pharmacodynamic responses.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1993;11(6):S3-8.
1993: M G Hendriks; K L Kam; A J Pijl; Martin Pfaffendorf; Pieter A van Zwieten
The effects of hypertension and diabetes mellitus on the vascular reactivity of perfused mesenteric resistance arteries.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1993;11(5):S268-9.
1993: K L Kam; M G Hendriks; A J Pijl; Martin Pfaffendorf; Pieter A van Zwieten
Spontaneously hypertensive rats with diabetes: effects of some vasoconstrictors on isolated small arteries.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1993;11(5):S120-1.
1993: M G Hendriks; Martin Pfaffendorf; Pieter A van Zwieten
Characterization of the muscarinic receptors in the mesenteric vascular bed of spontaneously hypertensive rats.
Journal of hypertension 1993;11(12):1329-35.
1993: K L Kam; Martin Pfaffendorf; Pieter A van Zwieten
The influence of high glucose levels and/or hyperosmolarity on rat isolated aorta.
Journal of pharmacological and toxicological methods 1993;30(3):153-7.
1993: Pieter A van Zwieten
New avenues in antihypertensive drug treatment.
Clinical and experimental hypertension (New York, N.Y. : 1993) 1993;15(6):1205-20.
1993: M G Hendriks; Martin Pfaffendorf; Pieter A van Zwieten
The role of nitric oxide and potassium channels in endothelium-dependent vasodilation in SHR.
Blood pressure 1993;2(3):233-43.
1993: A J Pijl; Martin Pfaffendorf; Pieter A van Zwieten
Hemodynamic and antiischemic effects of nifedipine, lacidipine, and nisoldipine in rat isolated working heart.
Journal of cardiovascular pharmacology 1993;22(3):381-7.
1993: T A Bruning; PC Chang; Gerard J Blauw; P Vermeij; Pieter A van Zwieten
Serotonin-induced vasodilatation in the human forearm is mediated by the "nitric oxide-pathway": no evidence for involvement of the 5-HT3-receptor.
Journal of cardiovascular pharmacology 1993;22(1):44-51.
1993: J Zhang; Martin Pfaffendorf; Pieter A van Zwieten
Positive inotropic action of angiotensin II in the pithed rat.
Naunyn-Schmiedeberg's archives of pharmacology 1993;347(6):658-63.
1993: J Zhang; J C Van Meel; Pieter A van Zwieten
Antihypertensive activity of the novel, nonpeptide angiotensin II receptor antagonists BIBS 39 and BIBS 222 in conscious renal hypertensive rats.
Pharmacology 1993;46(5):241-7.
1993: R Schwietert; D Wilhelm; B Wilffert; Pieter A van Zwieten
Functional study on the effects of nifedipine, cromakalim, and the absence of extracellular Ca2+ on alpha 1-adrenoceptor-mediated excitation-contraction coupling in isolated rat portal vein: comparison with depolarization-mediated excitation-contraction coupling.
Journal of cardiovascular pharmacology 1993;21(5):739-48.
1993: J B Heijnis; Pieter A van Zwieten
Effects of calcium antagonists on K(+)-induced contraction in isolated aorta from diabetic and age-matched control rats.
Pharmacology 1993;46(4):193-7.
1993: Pieter A van Zwieten; Harry B van Wezel
Antihypertensive drug treatment in the perioperative period.
Journal of cardiothoracic and vascular anesthesia 1993;7(2):213-26.
1993: Pieter A van Zwieten
An overview of the pharmacodynamic properties and therapeutic potential of combined alpha- and beta-adrenoceptor antagonists.
Drugs 1993;45(4):509-17.
1993: Pieter A van Zwieten; Martin Pfaffendorf
Similarities and differences between calcium antagonists: pharmacological aspects.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1993;11(1):S3-11.
1993: M G Hendriks; K L Kam; A J Pijl; Martin Pfaffendorf; Pieter A van Zwieten
The effects of hypertension and diabetes mellitus on the vascular reactivity of resistance arteries.
Blood pressure 1993;2(1):69-76.
1993: Martin Pfaffendorf; M J Mathy; Pieter A van Zwieten
In vitro effects of nifedipine, nisoldipine, and lacidipine on rat isolated coronary small arteries.
Journal of cardiovascular pharmacology 1993;21(3):496-502.
1993: J S Zhang; J C Van Meel; Martin Pfaffendorf; Pieter A van Zwieten
Characterization of the angiotensin II-receptor subtype in the longitudinal smooth muscle of the rat portal vein.
Naunyn-Schmiedeberg's archives of pharmacology 1993;347(2):220-4.
1993: Martin Pfaffendorf; M J Mathy; Pieter A van Zwieten
Effects of manidipine and other calcium antagonists on rat renal arcuate arteries.
American heart journal 1993;125(2 Pt 2):571-7.
1993: Pieter A van Zwieten
Protective effects of calcium antagonists in different organs and tissues.
American heart journal 1993;125(2 Pt 2):566-71.
1993: J Zhang; J C Van Meel; Martin Pfaffendorf; Pieter A van Zwieten
Cholera toxin but not pertussis toxin inhibits angiotensin II-enhanced contractions in the rat portal vein.
European journal of pharmacology 1993;230(1):95-7.
1993: Martin Pfaffendorf; Pieter A van Zwieten
Mediation by the same muscarinic receptor subtype of phasic and tonic contractile activities in the rat isolated portal vein.
British journal of pharmacology 1993;108(1):132-8.
1993: Pieter A van Zwieten
Pharmacodynamic profile of carvedilol.
Cardiology 1993;82 Suppl 3():19-23.
1993: M J Mertens; Martin Pfaffendorf; Pieter A van Zwieten
Differential response of hypertrophied rat hearts to various alpha 1-adrenoceptor agonists.
Fundamental & clinical pharmacology 1993;7(2):93-101.
1993: A J Pijl; Martin Pfaffendorf; M J Mathy; Pieter A van Zwieten
Cardioprotection by nifedipine in isolated working hearts: a comparative study on three different types of experimental ischemia.
Journal of cardiovascular pharmacology 1993;21(1):70-6.
1992: Pieter A van Zwieten
Comparative mechanisms of action of diuretic drugs in hypertension.
European heart journal 1992;13 Suppl G():2-4.
1992: M G Hendriks; Martin Pfaffendorf; Pieter A van Zwieten
Characterization of the muscarinic receptor subtype mediating vasodilation in the rat perfused mesenteric vascular bed preparation.
Journal of autonomic pharmacology 1992;12(6):411-20.
1992: Pieter A van Zwieten
Development and trends in the drug treatment of essential hypertension.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1992;10(7):S1-12.
1992: M J Mertens; Martin Pfaffendorf; Pieter A van Zwieten
Impaired vasodilator and chronotropic responses to 5-hydroxytryptamine in two models of hypertension-associated cardiac hypertrophy.
Blood pressure 1992;1(4):254-9.
1992: M J Mertens; M J Mathy; Martin Pfaffendorf; Pieter A van Zwieten
Depressed inotropic response to beta-adrenoceptor agonists in the presence of advanced cardiac hypertrophy in hearts from rats with induced aortic stenosis and from spontaneously hypertensive rats.
Journal of hypertension 1992;10(11):1361-8.
1992: J B Heijnis; Pieter A van Zwieten
Enhanced inotropic responsiveness to alpha 1-adrenoceptor stimulation in isolated working hearts from diabetic rats.
Journal of cardiovascular pharmacology 1992;20(4):559-62.
1992: J B Heijnis; M J Mathy; Martin Pfaffendorf; Pieter A van Zwieten
Differential effects of alpha 1- and alpha 2-adrenoceptor agonists on peripheral vasoconstriction in pithed diabetic rats.
Journal of cardiovascular pharmacology 1992;20(4):554-8.
1992: Pieter A van Zwieten
The cholinergic nervous system in hypertension: a neglected issue.
Blood pressure 1992;1(2):68-71.
1992: Pieter A van Zwieten; G J Blauw; P van Brummelen
Serotonergic receptors and drugs in hypertension.
Pharmacology & toxicology 1992;70(6 Pt 2):S17-22.
1992: H R Schwietert; M J Mathy; D Wilhelm; B Wilffert; Martin Pfaffendorf; Pieter A van Zwieten
Alpha 1-adrenoceptor-mediated Ca(2+)-entry from the extracellular fluid and Ca(2+)-release from intracellular stores: no role for alpha 1A,B-adrenoceptor subtypes in the pithed rat.
Journal of autonomic pharmacology 1992;12(3):125-36.
1992: Pieter A van Zwieten
Different types of centrally acting antihypertensive drugs.
European heart journal 1992;13 Suppl A():18-21.
1992: M J Mertens; HD Batink; Martin Pfaffendorf; Pieter A van Zwieten
Impaired inotropic response to alpha 1- but not to beta-adrenoceptor stimulation in isolated hearts from spontaneously hypertensive rats.
Journal of hypertension 1992;10(2):143-8.
1992: R Schwietert; D Wilhelm; B Wilffert; Pieter A van Zwieten
The effect of some alpha-adrenoceptor antagonists on spontaneous myogenic activity in the rat portal vein and the putative involvement of ATP-sensitive K+ channels.
European journal of pharmacology 1992;211(1):87-95.
1992: Pieter A van Zwieten
The role of alpha- and beta-adrenoceptor blockade in antihypertensive treatment.
The Clinical investigator 1992;70 Suppl 1():S7-12.
1991: M G Hendriks; Martin Pfaffendorf; Pieter A van Zwieten
Characterization of the muscarinic receptors in the mesenteric vascular bed of spontaneously hypertensive rats.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1991;9(6):S188-9.
1991: Pieter A van Zwieten
Adrenergic and muscarinergic receptors: classification, pathophysiological relevance and drug target.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1991;9(6):S18-27.
1991: M J Mertens; Martin Pfaffendorf; Pieter A van Zwieten
Cardiac effects of serotonin in hypertension.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1991;9(6):S156-7.
1991: J B Heijnis; Ruben Coronel; Pieter A van Zwieten
The effects of calcium antagonists on extracellular potassium accumulation during global ischaemia in isolated perfused rat hearts.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1991;5(6):1035-41.
1991: M J Mertens; HD Batink; Martin Pfaffendorf; Pieter A van Zwieten
Depressed inotropic response to alpha 1-adrenoceptor agonists in hearts from spontaneously hypertensive rats.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1991;9(6):S66-7.
1991: R van den Ende; HD Batink; Martin Pfaffendorf; Pieter A van Zwieten
Discrepancies between inotropic responses and beta-adrenoceptor characteristics after global ischemia in isolated hearts.
Journal of cardiovascular pharmacology 1991;18(5):679-86.
1991: J B Heijnis; M J Mathy; Pieter A van Zwieten
Effects of nifedipine on global myocardial ischemic injury in hearts from diabetic and age-matched control rats.
Journal of cardiovascular pharmacology 1991;18(4):542-7.
1991: H R Schwietert; D Wilhelm; B Wilffert; Pieter A van Zwieten
Differences between full and partial alpha-adrenoceptor agonists in eliciting phasic and tonic types of responses in the longitudinal smooth muscle of the rat portal vein.
Naunyn-Schmiedeberg's archives of pharmacology 1991;344(2):206-12.
1991: P N van Heiningen; HD Batink; Pieter A van Zwieten
Angiotensin II-induced increase in slowly exchanging 45Ca2+ in relation to contractile responses of rat and guinea-pig aorta.
Naunyn-Schmiedeberg's archives of pharmacology 1991;344(1):107-13.
1991: J B Heijnis; M J Mathy; Pieter A van Zwieten
Effects of various calcium antagonists in isolated perfused hearts from diabetic and age-matched control rats.
Journal of cardiovascular pharmacology 1991;17(6):983-9.
1991: J G Hugtenburg; M J Mathy; N de Haan; J J Beckeringh; Pieter A van Zwieten
The influence of calcium antagonists on the adenine nucleotide metabolism in the guinea-pig working heart during ischaemia and reperfusion.
Naunyn-Schmiedeberg's archives of pharmacology 1991;343(5):496-504.
1991: H R Schwietert; M A Gouw; D Wilhelm; B Wilffert; Pieter A van Zwieten
The role of alpha 1-adrenoceptor subtypes in the phasic and tonic responses to phenylephrine in the longitudinal smooth muscle of the rat portal vein.
Naunyn-Schmiedeberg's archives of pharmacology 1991;343(5):463-71.
1991: Gerard J Blauw; P van Brummelen; C J Doorenbos; E A van der Velde; Pieter A van Zwieten
The acute and chronic antihypertensive effects of ketanserin cannot be explained by blockade of vascular serotonin, type 2, receptors or alpha 1-adrenergic receptors.
Clinical pharmacology and therapeutics 1991;49(4):377-84.
1991: Gerard J Blauw; A H Bom; P van Brummelen; J Camps; J W Arndt; P D Verdouw; PC Chang; Pieter A van Zwieten; P R Saxena
Effects of 5-hydroxytryptamine on capillary and arteriovenous anastomotic blood flow in the human hand and forearm and in the pig hind leg.
Journal of cardiovascular pharmacology 1991;17(2):316-24.
1990: Pieter A van Zwieten; G J Blauw; P van Brummelen
The role of serotonin in cardiovascular diseases and their treatment.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1990;4(6):1443-7.
1990: M A Gouw; B Wilffert; Pieter A van Zwieten
Effects of inorganic cations on K(+)-, 5-hydroxytryptamine- and noradrenaline-induced contractions of the isolated rat jugular vein and aorta.
European journal of pharmacology 1990;185(2-3):147-55.
1990: J G Hugtenburg; M J Van Voorst; Jan van Marle; M J Mathy; J J Beckeringh; H A Van Veen; M G Hendriks; Pieter A van Zwieten
The influence of nifedipine and mioflazine on mitochondrial calcium overload in normoxic and ischaemic guinea-pig hearts.
European journal of pharmacology 1990;178(1):71-8.
1990: M A Gouw; B Wilffert; D Wermelskirchen; Pieter A van Zwieten
Ca2+ influx insensitive to organic Ca2+ entry blockers contributes to noradrenaline-induced contractions of the isolated guinea pig aorta.
Pharmacology 1990;40(5):277-87.
1990: Pieter A van Zwieten; G J Blauw; P van Brummelen
The role of 5-hydroxytryptamine and 5-hydroxytryptaminergic mechanisms in hypertension.
British journal of clinical pharmacology 1990;30 Suppl 1():69S-74S.
1990: Pieter A van Zwieten
Pharmacology of antihypertensive agents with multiple actions.
European journal of clinical pharmacology 1990;38 Suppl 2():S77-81.
1990: Pieter A van Zwieten; G J Blauw; P van Brummelen
Pathophysiological and pharmacotherapeutic aspects of serotonin and serotonergic drugs.
Clinical physiology and biochemistry 1990;8 Suppl 3():1-18.
1990: Pieter A van Zwieten
Comparative properties of various beta-blockers, with an outlook to the future.
Clinical physiology and biochemistry 1990;8 Suppl 2():18-27.
1990: F A Jonkman; Pieter A van Zwieten
Aggravation of the severity of the clonidine withdrawal syndrome in conscious rats by beta 2-adrenoceptor antagonists.
Drugs 1990;40 Suppl 4():45-7.
1990: Gerard J Blauw; C J Doorenbos; T A Bruning; P van Brummelen; Pieter A van Zwieten
Antihypertensive treatment with ketanserin shows no evidence of vascular serotonin2-receptor and alpha 1-adrenoceptor blockade.
Drugs 1990;40 Suppl 4():42-4.
1990: Pieter A van Zwieten; G J Blauw; P van Brummelen
Pharmacological profile of antihypertensive drugs with serotonin receptor and alpha-adrenoceptor activity.
Drugs 1990;40 Suppl 4():1-8; discussion 28-30.
1989: P N van Heiningen; V A Bohnenn; Pieter A van Zwieten
Calcium dependency of the angiotensin II-induced vasoconstriction in the rat.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1989;7(6):S158-9.
1989: F A Jonkman; P W Man; R Breurkes; Pieter A van Zwieten
Beta 2-adrenoceptor antagonists intensify clonidine withdrawal syndrome in conscious rats.
Journal of cardiovascular pharmacology 1989;14(6):886-91.
1989: J G Hugtenburg; M J Mathy; H W Boddeke; J J Beckeringh; Pieter A van Zwieten
Differences between negative inotropic and vasodilator effects of calcium antagonists acting on extra- and intracellular calcium movements in rat and guinea-pig cardiac preparations.
Naunyn-Schmiedeberg's archives of pharmacology 1989;340(5):567-75.
1989: J G Hugtenburg; M J Mathy; J J Beckeringh; Pieter A van Zwieten
The differential effect of calcium antagonists on the positive inotropic effects induced by calcium and monensin in cardiac preparations of rats and guinea-pigs.
Naunyn-Schmiedeberg's archives of pharmacology 1989;340(5):558-66.
1989: H W Boddeke; T J Jap; J G Hugtenburg; J B Heynis; R D Veldsema-Currie; B Wilffert; Pieter A van Zwieten
Protective activity of nifedipine and R 58735 upon damage caused by global ischemia in the guinea pig heart-lung preparation.
Basic research in cardiology 1989;84(5):489-98.
1989: Pieter A van Zwieten
Conclusions on the position of urapidil.
The American journal of cardiology 1989;64(7):38D-39D.
1989: Pieter A van Zwieten
Pharmacologic profile of urapidil.
The American journal of cardiology 1989;64(7):1D-6D.
1989: J G Hugtenburg; M J Mathy; R D Veldsema-Currie; H W Boddeke; J J Beckeringh; Pieter A van Zwieten
A comparison of the cardioprotective effects of calcium antagonists from different classes upon ischaemic damage in the guinea-pig working heart.
Naunyn-Schmiedeberg's archives of pharmacology 1989;340(1):126-34.
1989: J G Hugtenburg; T J Jap; M J Mathy; P N van Heiningen; V A Bohnenn; J B Heijnis; H W Boddeke; Pieter A van Zwieten
Cardioprotective effect of trimetazidine and nifedipine in guinea-pig hearts subjected to ischaemia.
Archives internationales de pharmacodynamie et de thérapie 1989;300():186-208.
1989: Gerard J Blauw; P van Brummelen; PC Chang; P Vermeij; Pieter A van Zwieten
Arterial and venous effects of serotonin in the forearm of healthy subjects are not age-related.
Journal of cardiovascular pharmacology 1989;14(1):14-21.
1989: M A Gouw; B Wilffert; Pieter A van Zwieten
Effects of calcium entry blocking agents on 5-hydroxytryptamine- and noradrenaline-induced contractions of rat isolated jugular vein and aorta.
Naunyn-Schmiedeberg's archives of pharmacology 1989;339(5):533-9.
1989: Pieter A van Zwieten
Drugs interacting with alpha adrenoceptors.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1989;3(2):121-33.
1989: A A Rondas; H W Boddeke; Henri Doods; L Thörig; Nicolaas J van Haeringen; Pieter A van Zwieten
Cholinergic receptors in the extraocular rectus muscle of the rabbit.
Ophthalmic research 1989;21(3):162-6.
1989: M A Gouw; B Wilffert; Pieter A van Zwieten
Different sensitivities for four calcium entry blockers of serotonin-, but not K+-induced contractions of isolated jugular vein and aorta of the rat.
Pharmacology 1989;38(5):289-97.
1988: P N van Heiningen; Pieter A van Zwieten
Role of calcium in the vasoconstriction induced by angiotensin II.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1988;6(4):S640-2.
1988: Gerard J Blauw; P van Brummelen; PC Chang; P Vermeij; Pieter A van Zwieten
5HT3 receptor-mediated vasodilation in the human forearm.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1988;6(4):S33-5.
1988: Pieter A van Zwieten
Basic pharmacology of alpha-adrenoceptor antagonists and hybrid drugs.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1988;6(2):S3-11.
1988: Pieter A van Zwieten
Neuro-endocrine changes as new targets in the drug treatment of congestive heart failure.
Pharmacological research communications 1988;20(12):1017-23.
1988: P N van Heiningen; Pieter A van Zwieten
Differential sensitivity to calcium entry blockade of angiotensin II-induced contractions of rat and guinea-pig aorta.
Archives internationales de pharmacodynamie et de thérapie 1988;296():118-30.
1988: Pieter A van Zwieten
The role of adrenoceptors in circulatory and metabolic regulation.
American heart journal 1988;116(5 Pt 2):1384-92.
1988: J T Knape; Pieter A van Zwieten
Positive chronotropic activity of angiotensin II in the pithed normotensive rat is primarily due to activation of cardiac beta 1-adrenoceptors.
Naunyn-Schmiedeberg's archives of pharmacology 1988;338(2):185-90.
1988: Pieter A van Zwieten
Receptor-mediated inotropic drugs.
European heart journal 1988;9 Suppl H():85-90.
1988: K J Van Charldorp; D Davidesko; Pieter A van Zwieten
Selectivity of methoctramine for muscarinic receptors in porcine cerebral arteries.
European journal of pharmacology 1988;150(1-2):197-9.
1988: E W Boddeke; B Wilffert; J B Heynis; J G Hugtenburg; W T Jap; R D Veldsema-Currie; Pieter A van Zwieten
The anti-ischaemic activity of the novel compound, CERM 11956, compared with that of bepridil and nifedipine in isolated guinea-pig hearts.
European journal of pharmacology 1988;149(3):195-203.
1988: Henri Doods; H W Boddeke; H O Kalkman; D Hoyer; M J Mathy; Pieter A van Zwieten
Central 5-HT1A receptors and the mechanism of the central hypotensive effect of (+)8-OH-DPAT, DP-5-CT, R28935, and urapidil.
Journal of cardiovascular pharmacology 1988;11(4):432-7.
1988: Cees Korstanje; E M Ten Brink; Pieter A van Zwieten
Interaction of calmodulin antagonists with alpha-adrenergic responses in pithed rats and in the perfused hindquarters of the rat.
European journal of pharmacology 1988;148(1):59-67.
1988: Gerard J Blauw; P van Brummelen; PC Chang; P Vermeij; Pieter A van Zwieten
Regional vascular effects of serotonin and ketanserin in young, healthy subjects.
Hypertension 1988;11(3):256-63.
1988: H W Boddeke; B Wilffert; J B Heynis; Pieter A van Zwieten
Investigation of the mechanism of negative inotropic activity of some calcium antagonists.
Journal of cardiovascular pharmacology 1988;11(3):321-5.
1988: Pieter A van Zwieten
Pharmacology of the alpha 2-adrenoceptor agonist rilmenidine.
The American journal of cardiology 1988;61(7):6D-14D.
1988: I Rinner; Henri Doods; K J van Charldorp; D Davidesko; Pieter A van Zwieten
Binding of muscarine receptor antagonists to pig coronary smooth muscle.
Naunyn-Schmiedeberg's archives of pharmacology 1988;337(2):146-50.
1988: T J Jap; H W Boddeke; V van de Haar; Pieter A van Zwieten
Hemodynamic effects of different calcium antagonists in the heart-lung preparation of the guinea pig.
Pharmacology 1988;36(6):371-9.
1988: J T Knape; Pieter A van Zwieten
Vasoconstrictor activity of vasopressin in the pithed rat.
Archives internationales de pharmacodynamie et de thérapie 1988;291():142-52.
1988: Gerard J Blauw; P van Brummelen; PC Chang; P Vermeij; Pieter A van Zwieten
Arterial dilatation and venous constriction induced by serotonin in the elderly.
Drugs 1988;36 Suppl 1():74-7.
1988: J T Knape; Pieter A van Zwieten
Enhanced pressor responses to angiotensin II caused by excessive sodium loading in the pithed rat.
Pharmacology 1988;37(3):165-70.
1988: H W Boddeke; B Wilffert; J G Hugtenburg; T J Jap; R D Veldsema-Currie; Pieter A van Zwieten
Anti-ischaemic activity of various calmodulin antagonists.
Pharmacology 1988;37(4):240-7.
1988: Gerard J Blauw; P van Brummelen; Pieter A van Zwieten
Serotonin induced vasodilatation in the human forearm is antagonized by the selective 5-HT3 receptor antagonist ICS 205-930.
Life sciences 1988;43(18):1441-9.
1988: Pieter A van Zwieten
Compensatory changes of sympathetic tone, the renin-angiotensin-aldosterone system, vasopressin, and ANF as potential therapeutic targets in congestive heart failure.
Zeitschrift für Kardiologie 1988;77 Suppl 5():67-76.
1988: Pieter A van Zwieten
Antihypertensive drugs interacting with alpha- and beta-adrenoceptors. A review of basic pharmacology.
Drugs 1988;35 Suppl 6():6-19.
1988: Gerard J Blauw; P van Brummelen; T Bruning; Pieter A van Zwieten
Local hemodynamic effects of serotonin and ketanserin in healthy subjects: studies in the forearm.
Journal of cardiovascular pharmacology 1988;11 Suppl 1():S41-3.
1987: Pieter A van Zwieten; P B Timmermans; P N van Heiningen
Receptor subtypes involved in the action of calcium antagonists.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1987;5(4):S21-8.
1987: J T Knape; Pieter A van Zwieten
Stimulation of vascular postsynaptic alpha 1-adrenoceptors by noradrenaline, released by angiotensin II in pithed rat preparations.
Archives internationales de pharmacodynamie et de thérapie 1987;290(1):64-76.
1987: Cees Korstanje; Pieter A van Zwieten
Inhibition of vasoconstriction to cirazoline by calcium-entry blockade after phenoxybenzamine in rat perfused hindquarters.
Naunyn-Schmiedeberg's archives of pharmacology 1987;336(4):409-14.
1987: H W Boddeke; B Wilffert; J B Heynis; V van de Haar Keuken; F A Jonkman; Pieter A van Zwieten
A comparison of the cardiac and vasodilatory effects of some calcium entry blockers in perfused isolated guinea-pig hearts.
Archives internationales de pharmacodynamie et de thérapie 1987;288(2):175-85.
1987: P van Brummelen; K Jie; P B Timmermans; Pieter A van Zwieten
Heterogeneity of vascular alpha-adrenoceptors in man.
Canadian journal of physiology and pharmacology 1987;65(8):1644-8.
1987: Henri Doods; M J Mathy; D Davidesko; K J van Charldorp; A de Jonge; Pieter A van Zwieten
Selectivity of muscarinic antagonists in radioligand and in vivo experiments for the putative M1, M2 and M3 receptors.
The Journal of pharmacology and experimental therapeutics 1987;242(1):257-62.
1987: K J Van Charldorp; A De Jonge; D Davidesko; I Rinner; Henri Doods; Pieter A van Zwieten
Coronary constriction induced by vagal stimulation in the isolated rat heart.
European journal of pharmacology 1987;136(1):135-6.
1987: K Jie; P Van Brummelen; P Vermey; P B Timmermans; Pieter A van Zwieten
Postsynaptic alpha 1- and alpha 2-adrenoceptors in human blood vessels: interactions with exogenous and endogenous catecholamines.
European journal of clinical investigation 1987;17(2):174-81.
1987: K Jie; P van Brummelen; P Vermey; P B Timmermans; Pieter A van Zwieten
Modulation of noradrenaline release by peripheral presynaptic alpha 2-adrenoceptors in humans.
Journal of cardiovascular pharmacology 1987;9(4):407-13.
1987: K Jie; P van Brummelen; P Vermey; P B Timmermans; Pieter A van Zwieten
Influence of calcium entry blockade on alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in the forearm of hypertensive patients.
European journal of clinical pharmacology 1987;32(2):115-20.
1987: Pieter A van Zwieten; M J Mathy; H W Boddeke; Henri Doods
Central hypotensive activity of ketanserin in cats.
Journal of cardiovascular pharmacology 1987;10 Suppl 3():S54-8.
1987: Pieter A van Zwieten
Pathophysiological relevance of serotonin.
Journal of cardiovascular pharmacology 1987;10 Suppl 3():S19-25.
1986: F A Jonkman; H W Boddeke; Pieter A van Zwieten
Protective activity of calcium entry blockers against ouabain intoxication in anesthetized guinea pigs.
Journal of cardiovascular pharmacology 1986;8(5):1009-13.
1986: Henri Doods; D Davidesko; M J Mathy; HD Batink; A de Jonge; Pieter A van Zwieten
Discrimination by N-ethylmaleimide between the chronotropic and inotropic response to muscarinic receptor stimulation in rat atrium.
Naunyn-Schmiedeberg's archives of pharmacology 1986;333(2):182-5.
1986: Cees Korstanje; R Sprenkels; Henri Doods; J G Hugtenburg; E Boddeke; HD Batink; M J Thoolen; Pieter A van Zwieten
Characterization of flufylline, fluprofylline, ritanserin, butanserin and R 56413 with respect to in-vivo alpha 1-,alpha 2- and 5-HT2-receptor antagonism and in-vitro affinity for alpha 1-,alpha 2- and 5-HT2-receptors: comparison with ketanserin.
The Journal of pharmacy and pharmacology 1986;38(5):374-9.
1986: Pieter A van Zwieten; M J Thoolen; F A Jonkman; B Wilffert; A de Jonge; P B Timmermans
Central and peripheral effects of S 3341 [(N-dicyclopropylmethyl)-amino-2-oxazoline] in animal models.
Archives internationales de pharmacodynamie et de thérapie 1986;279(1):130-49.
1986: K Jie; P van Brummelen; P Vermey; P B Timmermans; Pieter A van Zwieten
Alpha 1-and alpha 2-adrenoceptor mediated vasoconstriction in the forearm of normotensive and hypertensive subjects.
Journal of cardiovascular pharmacology 1986;8(1):190-6.
1985: K J van Charldorp; A de Jonge; M J Thoolen; Pieter A van Zwieten
Subclassification of muscarinic receptors in the heart, urinary bladder and sympathetic ganglia in the pithed rat. Selectivity of some classical agonists.
Naunyn-Schmiedeberg's archives of pharmacology 1985;331(4):301-6.
1985: K Jie; P van Brummelen; P Vermey; P B Timmermans; Pieter A van Zwieten
Alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in the forearm: differences between normotensive and hypertensive subjects.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1985;3(3):S89-91.
1985: K Jie; P van Brummelen; P Vermey; P B Timmermans; Pieter A van Zwieten
Differences between exogenous and endogenous noradrenaline in the effects on vascular post-synaptic alpha 1- and alpha 2-adrenoceptors in man.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1985;3(3):S145-7.
1985: Cees Korstanje; M J Mathy; K van Charldorp; A de Jonge; Pieter A van Zwieten
Influence of respiratory acidosis or alkalosis on pressor responses mediated by alpha 1- and alpha 2-adrenoceptors in pithed normotensive rats.
Naunyn-Schmiedeberg's archives of pharmacology 1985;330(3):187-92.
1985: F A Jonkman; P W Man; M J Thoolen; Pieter A van Zwieten
Location of the mechanism of the clonidine withdrawal tachycardia in rats.
The Journal of pharmacy and pharmacology 1985;37(8):580-2.
1985: Henri Doods; H O Kalkman; A De Jonge; M J Thoolen; B Wilffert; P B Timmermans; Pieter A van Zwieten
Differential selectivities of RU 24969 and 8-OH-DPAT for the purported 5-HT1A and 5-HT1B binding sites. Correlation between 5-HT1A affinity and hypotensive activity.
European journal of pharmacology 1985;112(3):363-70.
1985: L Thörig; P F Hoyng; P B Timmermans; Pieter A van Zwieten
M-7 lowers rabbit intraocular pressure.
Ophthalmic research 1985;17(6):362-72.
1985: P van Brummelen; K Jie; P Vermey; P B Timmermans; Pieter A van Zwieten
Vascular alpha-adrenoceptors in man: interactions with adrenaline and noradrenaline.
Clinical science (London, England : 1979) 1985;68 Suppl 10():151s-153s.
1984: K Jie; P van Brummelen; P Vermey; P B Timmermans; Pieter A van Zwieten
Effects of exogenous adrenaline and noradrenaline on vascular postsynaptic alpha 1- and alpha 2-adrenoceptors in man.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1984;2(3):S119-21.
1984: Cees Korstanje; Henri Doods; A De Jonge; M J Thoolen; B Wilffert; P B Timmermans; Pieter A van Zwieten
Affinity of WY 26703 for central and peripheral alpha 1- and alpha 2-adrenoreceptors in the rat; comparison with yohimbine.
Journal of autonomic pharmacology 1984;4(4):287-93.
1984: A de Jonge; D Davidesko; M J Mathy; M J Thoolen; B Wilffert; P van Brummelen; P B Timmermans; Pieter A van Zwieten
Effect of pithing on the postjunctional sympatho-inhibitory action of captopril in cats.
Naunyn-Schmiedeberg's archives of pharmacology 1984;328(1):30-2.
1984: Cees Korstanje; B Wilffert; A de Jonge; M J Thoolen; P B Timmermans; Pieter A van Zwieten
Calcium influx-dependent and -independent alpha 1-adrenoceptor-mediated processes of vasoconstriction in vivo do not operate via different alpha 1-adrenoceptor subtypes.
Journal of cardiovascular pharmacology 1984;6(6):1102-8.
1984: B Wilffert; P N van Heiningen; M J Mathy; A de Jonge; M J Thoolen; P B Timmermans; Pieter A van Zwieten
Interactions between the putative calcium entry promotor Bay k 8644 and pressor responses produced by alpha 1- and alpha 2-adrenoceptor agonists in the pithed normotensive rat.
Naunyn-Schmiedeberg's archives of pharmacology 1984;328(1):76-82.
1984: F A Jonkman; M J Thoolen; B Wilffert; A de Jonge; P B Timmermans; Pieter A van Zwieten
Effect of salbutamol and the PDE-inhibitor RA 642 on the clonidine withdrawal syndrome in rats.
Journal of autonomic pharmacology 1984;4(3):199-206.
1984: B Wilffert; P N van Heiningen; M J Mathy; HD Batink; A de Jonge; M J Thoolen; P B Timmermans; Pieter A van Zwieten
Lack of relationship between intrinsic activity and susceptibility of pressor responses to blockade by nifedipine among the alpha 2-adrenoceptor agonists B-HT 920 and B-HT 958.
Naunyn-Schmiedeberg's archives of pharmacology 1984;327(1):90-2.
1984: B Wilffert; D Davidesko; A De Jonge; M J Thoolen; P B Timmermans; Pieter A van Zwieten
Interaction between the calcium entry blocker nifedipine with the alpha 1-adrenoreceptor-mediated increase in diastolic pressure elicited by catecholamines.
Journal of autonomic pharmacology 1984;4(2):87-92.
1984: K Jie; P van Brummelen; P Vermey; P B Timmermans; Pieter A van Zwieten
Identification of vascular postsynaptic alpha 1- and alpha 2-adrenoceptors in man.
Circulation research 1984;54(4):447-52.
1984: P B Timmermans; M J Mathy; B Wilffert; H O Kalkman; G Smit; D Dijkstra; A S Horn; Pieter A van Zwieten
Alpha 1/alpha 2-adrenoceptor agonist selectivity of mono- and dihydroxy-2-N,N-DI-n-propylaminotetralins.
European journal of pharmacology 1984;97(1-2):55-65.
1983: H O Kalkman; H W Boddeke; P B Timmermans; Pieter A van Zwieten
Calcium-dependency of the pressor responses to selective 5-hydroxytryptamine receptor agonists in pithed rats.
Journal of autonomic pharmacology 1983;3(4):281-6.
1983: P B Timmermans; M J Mathy; B Wilffert; H O Kalkman; M J Thoolen; A de Jonge; J C van Meel; Pieter A van Zwieten
Differential effect of calcium entry blockers on alpha 1-adrenoceptor-mediated vasoconstriction in vivo.
Naunyn-Schmiedeberg's archives of pharmacology 1983;324(4):239-45.
1983: B Wilffert; D Davidesko; A De Jonge; M J Thoolen; P B Timmermans; Pieter A van Zwieten
Role of ganglionic M-1 and M-2 receptors in the neuronal control of the cardiovascular system of the normotensive rat as determined with pilocarpine.
European journal of pharmacology 1983;95(1-2):109-16.
1983: L Thörig; Nicolaas J van Haeringen; P B Timmermans; Pieter A van Zwieten
Peroxidase secretion from rat lacrimal gland cells in vitro: II. The role of calcium in stimulus-secretion coupling.
Experimental eye research 1983;37(5):485-92.
1983: L Thörig; Nicolaas J van Haeringen; P B Timmermans; Pieter A van Zwieten
Peroxidase secretion from rat lacrimal gland cells in vitro. I. Alpha-adrenergic stimulation in the absence of alpha-adrenoceptors.
Experimental eye research 1983;37(5):475-83.
1983: B Wilffert; M A Gouw; P B Timmermans; Pieter A van Zwieten
Interaction between beta 2-adrenoceptor-mediated vasodilation and alpha 1-adrenoceptor-mediated vasoconstriction in the pithed normotensive rat.
Journal of cardiovascular pharmacology 1983;5(5):829-35.
1983: B Wilffert; M A Gouw; P B Timmermans; Pieter A van Zwieten
Interaction between beta 2-adrenoceptor-mediated vasodilation and alpha 2-adrenoceptor-mediated vasoconstriction in the pithed normotensive rat.
Journal of cardiovascular pharmacology 1983;5(5):822-8.
1983: B Wilffert; D Davidesko; P B Timmermans; Pieter A van Zwieten
Differential role of M-1 and M-2 receptors in sympathetic ganglia of the pithed normotensive rat in alpha adrenoceptor-mediated vasoconstriction.
The Journal of pharmacology and experimental therapeutics 1983;226(3):855-60.
1983: H O Kalkman; H W Boddeke; Henri Doods; P B Timmermans; Pieter A van Zwieten
Hypotensive activity of serotonin receptor agonists in rats is related to their affinity for 5-HT1 receptors.
European journal of pharmacology 1983;91(1):155-6.
1983: P B Timmermans; B Wilffert; D Davidesko; M J Mathy; D Dijkstra; A S Horn; Pieter A van Zwieten
Re-evaluation of the selectivity of 2-N,N-dimethylamino-5,6-dihydroxy-1,2,3, 4-tetrahydronaphthalene (M-7) as an agonist of postjunctional alpha-2 adrenoceptors in the pithed normotensive rat.
The Journal of pharmacology and experimental therapeutics 1983;225(2):407-9.
1983: A De Jonge; J T Knape; J C Van Meel; H O Kalkman; B Wilffert; M J Thoolen; P Van Brummelen; P B Timmermans; Pieter A van Zwieten
Effect of captopril on sympathetic neurotransmission in pithed normotensive rats.
European journal of pharmacology 1983;88(2-3):231-40.
1983: P B Timmermans; A de Jonge; J C van Meel; M J Mathy; Pieter A van Zwieten
Influence of nifedipine on functional responses in vivo initiated at alpha 2-adrenoceptors.
Journal of cardiovascular pharmacology 1983;5(1):1-11.
1983: B Wilffert; M A Gouw; P B Timmermans; Pieter A van Zwieten
Cardiovascular effects of dopamine and some methylated and fluorinated derivatives in pithed normotensive rats.
Pharmacology 1983;27(3):140-9.
1982: A de Jonge; J T Knape; J C van Meel; H O Kalkman; B Wilffert; M J Thoolen; P B Timmermanns; Pieter A van Zwieten
Effect of converting enzyme inhibition and angiotensin receptor blockade on the vasoconstriction mediated by alpha 1-and alpha 2-adrenoceptor stimulation in pithed normotensive rats.
Naunyn-Schmiedeberg's archives of pharmacology 1982;321(4):309-13.
1982: B Wilffert; M A Gouw; A De Jonge; P B Timmermans; Pieter A van Zwieten
Indications for vascular alpha- and beta-2 adrenoceptors in synapses of the muscarinic pathway in the pithed normotensive rat.
The Journal of pharmacology and experimental therapeutics 1982;223(1):219-23.
1982: L Thörig; Nicolaas J van Haeringen; P B Timmermans; Pieter A van Zwieten
Alpha-adrenoceptor control of peroxidase secretion from rat lacrimal gland cells in vitro.
Experimental eye research 1982;35(1):29-41.
1981: A De Jonge; B Wilffert; H O Kalkman; J C Van Meel; M J Thoolen; P B Timmermans; Pieter A van Zwieten
Captopril impairs the vascular smooth muscle contraction mediated by postsynaptic alpha 2-adrenoceptors in the pithed rat.
European journal of pharmacology 1981;74(4):385-6.
1981: J C Van Meel; A de Jonge; H O Kalkman; B Wilffert; P B Timmermans; Pieter A van Zwieten
Organic and inorganic calcium antagonists reduce vasoconstriction in vivo mediated by postsynaptic alpha 2-adrenoceptors.
Naunyn-Schmiedeberg's archives of pharmacology 1981;316(4):288-93.
1981: J C Van Meel; A De Jonge; H O Kalkman; B Wilffert; P B Timmermans; Pieter A van Zwieten
Vascular smooth muscle contraction initiated by postsynaptic alpha 2-adrenoceptor activation is induced by an influx of extracellular calcium.
European journal of pharmacology 1981;69(2):205-8.