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John VanCott

Research Profile

Living Beings

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Physiology

Immunity, Mucosal

Disorders

Rotavirus Infections

Chemicals & Drugs

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Publications

TOP 3
John L VanCott; Anne E Prada; Monica M McNeal; Susan C Stone; Mitali Basu; Bert Huffer; Kristi L Smiley; Mingyuan Shao; Judy A Bean; John Clements; Anthony H-C Choi; Richard L Ward
Mice develop effective but delayed protective immune responses when immunized as neonates either intranasally with nonliving VP6/LT(R192G) or orally with live rhesus rotavirus vaccine candidates.
John L VanCott; Monica M McNeal; Anthony H-C Choi; Richard L Ward
The role of interferons in rotavirus infections and protection.
Anthony H-C Choi; Monica M McNeal; Mitali Basu; Judy A Bean; John L VanCott; John Clements; Richard L Ward
Functional mapping of protective epitopes within the rotavirus VP6 protein in mice belonging to different haplotypes.

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All Publications

2006: John L VanCott; Anne E Prada; Monica M McNeal; Susan C Stone; Mitali Basu; Bert Huffer; Kristi L Smiley; Mingyuan Shao; Judy A Bean; John Clements; Anthony H-C Choi; Richard L Ward
Mice develop effective but delayed protective immune responses when immunized as neonates either intranasally with nonliving VP6/LT(R192G) or orally with live rhesus rotavirus vaccine candidates.
Journal of virology 2006;80(10):4949-61.
2003: John L VanCott; Monica M McNeal; Anthony H-C Choi; Richard L Ward
The role of interferons in rotavirus infections and protection.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2003;23(3):163-70.
2003: Anthony H-C Choi; Monica M McNeal; Mitali Basu; Judy A Bean; John L VanCott; John Clements; Richard L Ward
Functional mapping of protective epitopes within the rotavirus VP6 protein in mice belonging to different haplotypes.
Vaccine 2003;21(7-8):761-7.
2002: Anthony H-C Choi; Monica M McNeal; Mitali Basu; Jason A Flint; Susan C Stone; John Clements; Judy A Bean; Stacy A Poe; John L VanCott; Richard L Ward
Intranasal or oral immunization of inbred and outbred mice with murine or human rotavirus VP6 proteins protects against viral shedding after challenge with murine rotaviruses.
Vaccine 2002;20(27-28):3310-21.
2002: Anthony H-C Choi; Monica M McNeal; Jason A Flint; Mitali Basu; Nils Lycke; John Clements; Judy A Bean; Heather L Davis; Michael J McCluskie; John L VanCott; Richard L Ward
The level of protection against rotavirus shedding in mice following immunization with a chimeric VP6 protein is dependent on the route and the coadministered adjuvant.
Vaccine 2002;20(13-14):1733-40.
2002: Monica M McNeal; John L VanCott; Anthony H-C Choi; Mitali Basu; Jason A Flint; Susan C Stone; John Clements; Richard L Ward
CD4 T cells are the only lymphocytes needed to protect mice against rotavirus shedding after intranasal immunization with a chimeric VP6 protein and the adjuvant LT(R192G).
Journal of virology 2002;76(2):560-8.
2001: John L VanCott; Monica M McNeal; J Flint; S A Bailey; Anthony H-C Choi; Richard L Ward
Role for T cell-independent B cell activity in the resolution of primary rotavirus infection in mice.
European journal of immunology 2001;31(11):3380-7.
2000: Anthony H-C Choi; Mitali Basu; Monica M McNeal; J Flint; John L VanCott; John Clements; Richard L Ward
Functional mapping of protective domains and epitopes in the rotavirus VP6 protein.
Journal of virology 2000;74(24):11574-80.
2000: Alexander Szalai; John L VanCott; Jerry R McGhee; John E Volanakis; William H Benjamin
Human C-reactive protein is protective against fatal Salmonella enterica serovar typhimurium infection in transgenic mice.
Infection and immunity 2000;68(10):5652-6.
2000: John L VanCott; Manuel A Franco; Harry B Greenberg; Steffanie Sabbaj; B Tang; R Murray; Jerry R McGhee
Protective immunity to rotavirus shedding in the absence of interleukin-6: Th1 cells and immunoglobulin A develop normally.
Journal of virology 2000;74(11):5250-6.
1999: David W Pascual; David Hone; S Hall; Frederik W van Ginkel; M Yamamoto; Nancy Walters; Kohtaro Fujihashi; R J Powell; Shaoguang Wu; John L VanCott; Hiroshi Kiyono; Jerry R McGhee
Expression of recombinant enterotoxigenic Escherichia coli colonization factor antigen I by Salmonella typhimurium elicits a biphasic T helper cell response.
Infection and immunity 1999;67(12):6249-56.
1999: Prosper N Boyaka; M Marinaro; John L VanCott; I Takahashi; Kohtaro Fujihashi; Masato Yamamoto; Frederik W van Ginkel; Raymond J Jackson; Hiroshi Kiyono; Jerry R McGhee
Strategies for mucosal vaccine development.
The American journal of tropical medicine and hygiene 1999;60(4 Suppl):35-45.
1998: John L VanCott; S N Chatfield; M Roberts; David Hone; E L Hohmann; David W Pascual; M Yamamoto; Hiroshi Kiyono; Jerry R McGhee
Regulation of host immune responses by modification of Salmonella virulence genes.
Nature medicine 1998;4(11):1247-52.
1998: Mi-Na Kweon; Kohtaro Fujihashi; John L VanCott; K Higuchi; Masato Yamamoto; Jerry R McGhee; Hiroshi Kiyono
Lack of orally induced systemic unresponsiveness in IFN-gamma knockout mice.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(4):1687-93.
1998: KA Benton; John L VanCott; David E Briles
Role of tumor necrosis factor alpha in the host response of mice to bacteremia caused by pneumolysin-deficient Streptococcus pneumoniae.
Infection and immunity 1998;66(2):839-42.
1997: John L VanCott; Mi-Na Kweon; Kohtaro Fujihashi; Masato Yamamoto; M Marinaro; Hiroshi Kiyono; Jerry R McGhee
Helper T subsets and cytokines for mucosal immunity and tolerance.
Behring Institute Mitteilungen 1997;(98):44-52.
1997: Kohtaro Fujihashi; Mi-Na Kweon; Hiroshi Kiyono; John L VanCott; Frederik W van Ginkel; Masato Yamamoto; Jerry R McGhee
A T cell/B cell/epithelial cell internet for mucosal inflammation and immunity.
Springer seminars in immunopathology 1997;18(4):477-94.
1997: Manuel A Franco; C Tin; Lusijah S Rott; John L VanCott; Jerry R McGhee; Harry B Greenberg
Evidence for CD8+ T-cell immunity to murine rotavirus in the absence of perforin, fas, and gamma interferon.
Journal of virology 1997;71(1):479-86.
1996: N Okahashi; Masato Yamamoto; John L VanCott; Steven N Chatfield; M Roberts; H Bluethmann; T Hiroi; Hiroshi Kiyono; Jerry R McGhee
Oral immunization of interleukin-4 (IL-4) knockout mice with a recombinant Salmonella strain or cholera toxin reveals that CD4+ Th2 cells producing IL-6 and IL-10 are associated with mucosal immunoglobulin A responses.
Infection and immunity 1996;64(5):1516-25.
1996: John L VanCott; T Kobayashi; Masato Yamamoto; S Pillai; Jerry R McGhee; Hiroshi Kiyono
Induction of pneumococcal polysaccharide-specific mucosal immune responses by oral immunization.
Vaccine 1996;14(5):392-8.
1996: John L VanCott; H F Staats; David W Pascual; M Roberts; Steven N Chatfield; Masato Yamamoto; M Coste; P B Carter; Hiroshi Kiyono; Jerry R McGhee
Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(4):1504-14.
1996: Masato Yamamoto; John L VanCott; N Okahashi; M Marinaro; Hiroshi Kiyono; Kohtaro Fujihashi; Raymond J Jackson; Steven N Chatfield; H Bluethmann; Jerry R McGhee
The role of Th1 and Th2 cells for mucosal IgA responses.
Annals of the New York Academy of Sciences 1996;778():64-71.
1996: Raymond J Jackson; M Marinaro; John L VanCott; Masato Yamamoto; N Okahashi; Kohtaro Fujihashi; Hiroshi Kiyono; Steven N Chatfield; Jerry R McGhee
Mucosal immunity: regulation by helper T cells and a novel method for detection.
Journal of biotechnology 1996;44(1-3):209-16.
1995: Shaoguang Wu; David W Pascual; John L VanCott; Jerry R McGhee; D R Maneval; Myron M Levine; David Hone
Immune responses to novel Escherichia coli and Salmonella typhimurium vectors that express colonization factor antigen I (CFA/I) of enterotoxigenic E. coli in the absence of the CFA/I positive regulator cfaR.
Infection and immunity 1995;63(12):4933-8.