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Peter Vandenabeele

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Demon Dieter; Van Damme Petra; Berghe Tom Vanden; Vandekerckhove Joël; Declercq Wim; Gevaert Kris; Vandenabeele Peter
Caspase substrates: easily caught in deep waters?
Ceelen Liesbeth M; Haesebrouck Freddy; D'Herde Katharina; Krysko Dmitri V; Favoreel Herman; Vandenabeele Peter; Ducatelle Richard; Decostere Annemie
Mitotic catastrophe as a prestage to necrosis in mouse liver cells treated with Helicobacter pullorum sonicates.
Korsakov Andrey V; Golovin Alexander V; De Gussem Kris; Sharygin Igor S; Vandenabeele Peter
First finding of burkeite in melt inclusions in olivine from sheared lherzolite xenoliths.

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All Publications

2009: Demon Dieter; Van Damme Petra; Berghe Tom Vanden; Vandekerckhove Joël; Declercq Wim; Gevaert Kris; Vandenabeele Peter
Caspase substrates: easily caught in deep waters?
Trends in biotechnology 2009;27(12):680-8.
2009: Ceelen Liesbeth M; Haesebrouck Freddy; D'Herde Katharina; Krysko Dmitri V; Favoreel Herman; Vandenabeele Peter; Ducatelle Richard; Decostere Annemie
Mitotic catastrophe as a prestage to necrosis in mouse liver cells treated with Helicobacter pullorum sonicates.
Journal of morphology 2009;270(8):921-8.
2009: Korsakov Andrey V; Golovin Alexander V; De Gussem Kris; Sharygin Igor S; Vandenabeele Peter
First finding of burkeite in melt inclusions in olivine from sheared lherzolite xenoliths.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2009;73(3):424-7.
2009: Vandenabeele Peter; Garcia-Moreno Renata; Mathis François; Leterme Kerstin; Van Elslande Elsa; Hocquet François-Philippe; Rakkaa Saïd; Laboury Dimitri; Moens Luc; Strivay David; Hartwig Melinda
Multi-disciplinary investigation of the tomb of Menna (TT69), Theban Necropolis, Egypt.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2009;73(3):546-52.
2009: Declercq Wim; Vanden Berghe Tom; Vandenabeele Peter
RIP kinases at the crossroads of cell death and survival.
Cell 2009;138(2):229-32.
2009: Verspurten Jelle; Gevaert Kris; Declercq Wim; Vandenabeele Peter
SitePredicting the cleavage of proteinase substrates.
Trends in biochemical sciences 2009;34(7):319-23.
2009: Lippens Saskia; Hoste Esther; Vandenabeele Peter; Agostinis Patrizia; Declercq Wim
Cell death in the skin.
Apoptosis : an international journal on programmed cell death 2009;14(4):549-69.
2009: Remijsen Quinten; Vanden Berghe Tom; Parthoens Eef; Asselbergh Bob; Vandenabeele Peter; Willems Jean
Inhibition of spontaneous neutrophil apoptosis by parabutoporin acts independently of NADPH oxidase inhibition but by lipid raft-dependent stimulation of Akt.
Journal of leukocyte biology 2009;85(3):497-507.
2009: De Gussem Kris; Vandenabeele Peter; Verbeken Annemieke; Moens Luc
Use of dendrograms of slice spectra as a new graphical tool for the interpretation of two-dimensional correlation spectra.
Applied spectroscopy 2009;63(1):73-80.
2008: da Silva Carlos Eduardo; Vandenabeele Peter; Edwards Howell G M; de Oliveira Luiz Fernando Cappa
NIR-FT-Raman spectroscopic analytical characterization of the fruits, seeds, and phytotherapeutic oils from rosehips.
Analytical and bioanalytical chemistry 2008;392(7-8):1489-96.
2008: Lamkanfi Mohamed; Kanneganti Thirumala-Devi; Van Damme Petra; Vanden Berghe Tom; Vanoverberghe Isabel; Vandekerckhove Joël; Vandenabeele Peter; Gevaert Kris; Núñez Gabriel
Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes.
Molecular & cellular proteomics : MCP 2008;7(12):2350-63.
2008: Notebaert Sofie; Demon Dieter; Vanden Berghe Tom; Vandenabeele Peter; Meyer Evelyne
Inflammatory mediators in Escherichia coli-induced mastitis in mice.
Comparative immunology, microbiology and infectious diseases 2008;31(6):551-65.
2008: Krysko Dmitri V; Diez-Fraile Araceli; Criel Godelieve; Svistunov Andrei A; Vandenabeele Peter; D'Herde Katharina
Life and death of female gametes during oogenesis and folliculogenesis.
Apoptosis : an international journal on programmed cell death 2008;13(9):1065-87.
2008: Vandenabeele Peter; Declercq Wim; Vanden Berghe Tom
Necrotic cell death and 'necrostatins': now we can control cellular explosion.
Trends in biochemical sciences 2008;33(8):352-5.
2008: Notebaert Sofie; Carlsen Harald; Janssen Daniel; Vandenabeele Peter; Blomhoff Rune; Meyer Evelyne
In vivo imaging of NF-kappaB activity during Escherichia coli-induced mammary gland infection.
Cellular microbiology 2008;10(6):1249-58.
2008: Vanlangenakker Nele; Vanden Berghe Tom; Krysko Dmitri V; Festjens Nele; Vandenabeele Peter
Molecular mechanisms and pathophysiology of necrotic cell death.
Current molecular medicine 2008;8(3):207-20.
2008: Krysko Dmitri V; Vanden Berghe Tom; D'Herde Katharina; Vandenabeele Peter
Apoptosis and necrosis: detection, discrimination and phagocytosis.
Methods (San Diego, Calif.) 2008;44(3):205-21.
2008: Gelder Joke De; Willemse-Erix Diana; Scholtes Maarten J; Sanchez Jorge I; Maquelin Kees; Vandenabeele Peter; Boever Patrick De; Puppels Gerwin J; Moens Luc; Vos Paul De
Monitoring poly(3-hydroxybutyrate) production in cupriavidus necator DSM 428 (H16) with raman spectroscopy.
Analytical chemistry 2008;80(6):2155-60.
2008: Vande Walle L; Lamkanfi M; Vandenabeele P
The mitochondrial serine protease HtrA2/Omi: an overview.
Cell death and differentiation 2008;15(3):453-60.
2008: Denecker Geertrui; Ovaere Petra; Vandenabeele Peter; Declercq Wim
Caspase-14 reveals its secrets.
The Journal of cell biology 2008;180(3):451-8.
2008: Demerjian Marianne; Hachem Jean-Pierre; Tschachler Erwin; Denecker Geertrui; Declercq Wim; Vandenabeele Peter; Mauro Theodora; Hupe Melanie; Crumrine Debra; Roelandt Truus; Houben Evi; Elias Peter M; Feingold Kenneth R
Acute modulations in permeability barrier function regulate epidermal cornification: role of caspase-14 and the protease-activated receptor type 2.
The American journal of pathology 2008;172(1):86-97.
2008: de Veij Marleen; Deneckere Annelien; Vandenabeele Peter; de Kaste Dries; Moens Luc
Detection of counterfeit Viagra with Raman spectroscopy.
Journal of pharmaceutical and biomedical analysis 2008;46(2):303-9.
2008: Krysko D V; Vandenabeele P
From regulation of dying cell engulfment to development of anti-cancer therapy.
Cell death and differentiation 2008;15(1):29-38.
2008: Shibata Hiroko; Yoshioka Yasuo; Ohkawa Akiko; Minowa Kyoko; Mukai Yohei; Abe Yasuhiro; Taniai Madoka; Nomura Tetsuya; Kayamuro Hiroyuki; Nabeshi Hiromi; Sugita Toshiki; Imai Sunao; Nagano Kazuya; Yoshikawa Tomoaki; Fujita Takuya; Nakagawa Shinsaku; Yamamoto Akira; Ohta Tsunetaka; Hayakawa Takao; Mayumi Tadanori; Vandenabeele Peter; Aggarwal Bharat B; Nakamura Teruya; Yamagata Yuriko; Tsunoda Shin-ichi; Kamada Haruhiko; Tsutsumi Yasuo
Creation and X-ray structure analysis of the tumor necrosis factor receptor-1-selective mutant of a tumor necrosis factor-alpha antagonist.
The Journal of biological chemistry 2008;283(2):998-1007.
2008: Krysko Dmitri V; Vanden Berghe Tom; Parthoens Eef; D'Herde Katharina; Vandenabeele Peter
Methods for distinguishing apoptotic from necrotic cells and measuring their clearance.
Methods in enzymology 2008;442():307-41.
2007: Kersse K; Vanden Berghe T; Lamkanfi M; Vandenabeele P
A phylogenetic and functional overview of inflammatory caspases and caspase-1-related CARD-only proteins.
Biochemical Society transactions 2007;35(Pt 6):1508-11.
2007: Resano Martin; García-Ruiz Esperanza; Alloza Ramiro; Marzo Maria P; Vandenabeele Peter; Vanhaecke Frank
Laser ablation-inductively coupled plasma mass spectrometry for the characterization of pigments in prehistoric rock art.
Analytical chemistry 2007;79(23):8947-55.
2007: De Gelder Joke; Scheldeman Patsy; Leus Karen; Heyndrickx Marc; Vandenabeele Peter; Moens Luc; De Vos Paul
Raman spectroscopic study of bacterial endospores.
Analytical and bioanalytical chemistry 2007;389(7-8):2143-51.
2007: Edwards Howell G M; Vandenabeele Peter; Jorge-Villar Susana E; Carter Elizabeth A; Perez Fernando Rull; Hargreaves Michael D
The Rio Tinto Mars analogue site: an extremophilic Raman spectroscopic study.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2007;68(4):1133-7.
2007: Korsakov Andrey V; Hutsebaut Didier; Theunissen Karel; Vandenabeele Peter; Stepanov Alexander S
Raman mapping of coesite inclusions in garnet from the Kokchetav Massif (Northern Kazakhstan).
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2007;68(4):1046-52.
2007: Vandenabeele Peter; Ortega-Avilès Mayahuel; Castilleros Dolores Tenorio; Moens Luc
Raman spectroscopic analysis of Mexican natural artists' materials.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2007;68(4):1085-8.
2007: Vercammen Dominique; Declercq Wim; Vandenabeele Peter; Van Breusegem Frank
Are metacaspases caspases?
The Journal of cell biology 2007;179(3):375-80.
2007: De Gelder Joke; De Gussem Kris; Vandenabeele Peter; Vancanneyt Marc; De Vos Paul; Moens Luc
Methods for extracting biochemical information from bacterial Raman spectra: focus on a group of structurally similar biomolecules--fatty acids.
Analytica chimica acta 2007;603(2):167-75.
2007: Kouloumpi Eleni; Vandenabeele Peter; Lawson Graham; Pavlidis Vassilios; Moens Luc
Analysis of post-Byzantine icons from the Church of the Assumption in Cephalonia, Ionian Islands, Greece: a multi-method approach.
Analytica chimica acta 2007;598(1):169-79.
2007: Vanden Berghe Tom; Declercq Wim; Vandenabeele Peter
NADPH oxidases: new players in TNF-induced necrotic cell death.
Molecular cell 2007;26(6):769-71.
2007: Lamkanfi Mohamed; Amer Amal; Kanneganti Thirumala-Devi; Muñoz-Planillo Raúl; Chen Grace; Vandenabeele Peter; Fortier Anne; Gros Philippe; Núñez Gabriel
The Nod-like receptor family member Naip5/Birc1e restricts Legionella pneumophila growth independently of caspase-1 activation.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(12):8022-7.
2007: Denecker Geertrui; Hoste Esther; Gilbert Barbara; Hochepied Tino; Ovaere Petra; Lippens Saskia; Van den Broecke Caroline; Van Damme Petra; D'Herde Katharina; Hachem Jean-Pierre; Borgonie Gaetan; Presland Richard B; Schoonjans Luc; Libert Claude; Vandekerckhove Joël; Gevaert Kris; Vandenabeele Peter; Declercq Wim
Caspase-14 protects against epidermal UVB photodamage and water loss.
Nature cell biology 2007;9(6):666-74.
2007: Kalai M; Suin V; Festjens N; Meeus A; Bernis A; Wang X-M; Saelens X; Vandenabeele P
The caspase-generated fragments of PKR cooperate to activate full-length PKR and inhibit translation.
Cell death and differentiation 2007;14(5):1050-9.
2007: Kanneganti Thirumala-Devi; Lamkanfi Mohamed; Kim Yun-Gi; Chen Grace; Park Jong-Hwan; Franchi Luigi; Vandenabeele Peter; Núñez Gabriel
Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling.
Immunity 2007;26(4):433-43.
2007: Vandenabeele P; Castro K; Hargreaves M; Moens L; Madariaga J M; Edwards H G M
Comparative study of mobile Raman instrumentation for art analysis.
Analytica chimica acta 2007;588(1):108-16.
2007: De Gussem Kris; Vandenabeele Peter; Verbeken Annemieke; Moens Luc
Chemotaxonomical identification of spores of macrofungi: possibilities of Raman spectroscopy.
Analytical and bioanalytical chemistry 2007;387(8):2823-32.
2007: De Gelder Joke; De Gussem Kris; Vandenabeele Peter; De Vos Paul; Moens Luc
Methods for extracting biochemical information from bacterial Raman spectra: an explorative study on Cupriavidus metallidurans.
Analytica chimica acta 2007;585(2):234-40.
2007: Vandenabeele Peter; Edwards Howell G M; Moens Luc
A decade of Raman spectroscopy in art and archaeology.
Chemical reviews 2007;107(3):675-86.
2007: Festjens N; Vanden Berghe T; Cornelis S; Vandenabeele P
RIP1, a kinase on the crossroads of a cell's decision to live or die.
Cell death and differentiation 2007;14(3):400-10.
2007: Vande Walle Lieselotte; Van Damme Petra; Lamkanfi Mohamed; Saelens Xavier; Vandekerckhove Joël; Gevaert Kris; Vandenabeele Peter
Proteome-wide Identification of HtrA2/Omi Substrates.
Journal of proteome research 2007;6(3):1006-15.
2007: Vandenabeele Peter
Archaeometry, an interdisciplinary approach.
Analytical and bioanalytical chemistry 2007;387(3):735.
2007: Vandenabeele Peter; Tate Jim; Moens Luc
Non-destructive analysis of museum objects by fibre-optic Raman spectroscopy.
Analytical and bioanalytical chemistry 2007;387(3):813-9.
2007: Lamkanfi M; Festjens N; Declercq W; Vanden Berghe T; Vandenabeele P
Caspases in cell survival, proliferation and differentiation.
Cell death and differentiation 2007;14(1):44-55.
2007: Cornelis Sigrid; Kersse Kristof; Festjens Nele; Lamkanfi Mohamed; Vandenabeele Peter
Inflammatory caspases: targets for novel therapies.
Current pharmaceutical design 2007;13(4):367-85.
2007: Schilders Geurt; Raijmakers Reinout; Malmegrim Kelen C R; Vande Walle Lieselotte; Saelens Xavier; Vree Egberts Wilma; van Venrooij Walther J; Vandenabeele Peter; Pruijn Ger J M
Caspase-mediated cleavage of the exosome subunit PM/Scl-75 during apoptosis.
Arthritis research & therapy 2007;9(1):R12.
2006: De Gussem Kris; Verbeken Annemieke; Vandenabeele Peter; De Gelder Joke; Moens Luc
Raman spectroscopic monitoring of Lactarius latex.
Phytochemistry 2006;67(23):2580-9.
2006: Krysko D V; Denecker G; Festjens N; Gabriels S; Parthoens E; D'Herde K; Vandenabeele P
Macrophages use different internalization mechanisms to clear apoptotic and necrotic cells.
Cell death and differentiation 2006;13(12):2011-22.
2006: Hutsebaut Didier; Vandroemme Joachim; Heyrman Jeroen; Dawyndt Peter; Vandenabeele Peter; Moens Luc; de Vos Paul
Raman microspectroscopy as an identification tool within the phylogenetically homogeneous 'Bacillus subtilis' group.
Systematic and applied microbiology 2006;29(8):650-60.
2006: Hall Krystyn Alter; Newton Paul N; Green Michael D; De Veij Marleen; Vandenabeele Peter; Pizzanelli David; Mayxay Mayfong; Dondorp Arjen; Fernandez Facundo M
Characterization of counterfeit artesunate antimalarial tablets from southeast Asia.
The American journal of tropical medicine and hygiene 2006;75(5):804-11.
2006: Vandenabeele Peter; Vanden Berghe Tom; Festjens Nele
Caspase inhibitors promote alternative cell death pathways.
Science's STKE : signal transduction knowledge environment 2006;2006(358):pe44.
2006: Krysko Dmitri V; D'Herde Katharina; Vandenabeele Peter
Clearance of apoptotic and necrotic cells and its immunological consequences.
Apoptosis : an international journal on programmed cell death 2006;11(10):1709-26.
2006: Festjens Nele; Vanden Berghe Tom; Vandenabeele Peter
Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response.
Biochimica et biophysica acta 2006;1757(9-10):1371-87.
2006: Festjens Nele; Cornelis Sigrid; Lamkanfi Mohamed; Vandenabeele Peter
Caspase-containing complexes in the regulation of cell death and inflammation.
Biological chemistry 2006;387(8):1005-16.
2006: Franchi Luigi; Amer Amal; Body-Malapel Mathilde; Kanneganti Thirumala-Devi; Ozören Nesrin; Jagirdar Rajesh; Inohara Naohiro; Vandenabeele Peter; Bertin John; Coyle Anthony; Grant Ethan P; Núñez Gabriel
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages.
Nature immunology 2006;7(6):576-82.
2006: Vandenabeele P; Moens L
Introducing students to Raman spectroscopy.
Analytical and bioanalytical chemistry 2006;385(2):209-11.
2006: Lamkanfi Mohamed; Declercq Wim; Vanden Berghe Tom; Vandenabeele Peter
Caspases leave the beaten track: caspase-mediated activation of NF-kappaB.
The Journal of cell biology 2006;173(2):165-71.
2006: Kanneganti Thirumala-Devi; Ozören Nesrin; Body-Malapel Mathilde; Amer Amal; Park Jong-Hwan; Franchi Luigi; Whitfield Joel; Barchet Winfried; Colonna Marco; Vandenabeele Peter; Bertin John; Coyle Anthony; Grant Ethan P; Akira Shizuo; Núñez Gabriel
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3.
Nature 2006;440(7081):233-6.
2006: Vanden Berghe Tom; Kalai Michael; Denecker Geertrui; Meeus Ann; Saelens Xavier; Vandenabeele Peter
Necrosis is associated with IL-6 production but apoptosis is not.
Cellular signalling 2006;18(3):328-35.
2006: Festjens N; Kalai M; Smet J; Meeus A; Van Coster R; Saelens X; Vandenabeele P
Butylated hydroxyanisole is more than a reactive oxygen species scavenger.
Cell death and differentiation 2006;13(1):166-9.
2005: Lippens S; Denecker G; Ovaere P; Vandenabeele P; Declercq W
Death penalty for keratinocytes: apoptosis versus cornification.
Cell death and differentiation 2005;12 Suppl 2():1497-508.
2005: Liu Jun; Zhao Min Q; Xu Lumei; Ramana C V; Declercq Wim; Vandenabeele Peter; Enelow Richard I
Requirement for tumor necrosis factor-receptor 2 in alveolar chemokine expression depends upon the form of the ligand.
American journal of respiratory cell and molecular biology 2005;33(5):463-9.
2005: Al-Lamki Rafia S; Wang Jun; Vandenabeele Peter; Bradley J Andrew; Thiru Sathia; Luo Dianghong; Min Wang; Pober Jordan S; Bradley John R
TNFR1- and TNFR2-mediated signaling pathways in human kidney are cell type-specific and differentially contribute to renal injury.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(12):1637-45.
2005: De Gussem Kris; Vandenabeele Peter; Verbeken Annemieke; Moens Luc
Raman spectroscopic study of Lactarius spores (Russulales, Fungi).
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2005;61(13-14):2896-908.
2005: Vandenabeele Peter; Lambert Karel; Matthys Sofie; Schudel Walter; Bergmans Anna; Moens Luc
In situ analysis of mediaeval wall paintings: a challenge for mobile Raman spectroscopy.
Analytical and bioanalytical chemistry 2005;383(4):707-12.
2005: Korsakov Andrey V; Vandenabeele Peter; Theunissen Karel
Discrimination of metamorphic diamond populations by Raman spectroscopy (Kokchetav, Kazakhstan).
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2005;61(10):2378-85.
2005: Castro K; Vandenabeele P; Rodríguez-Laso M D; Moens L; Madariaga J M
Improvements in the wallpaper industry during the second half of the 19th century: micro-Raman spectroscopy analysis of pigmented wallpapers.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2005;61(10):2357-63.
2005: Vandenabeele P; Bodé S; Alonso A; Moens L
Raman spectroscopic analysis of the Maya wall paintings in Ek'Balam, Mexico.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2005;61(10):2349-56.
2005: Hutsebaut Didier; Vandenabeele Peter; Moens Luc
Evaluation of an accurate calibration and spectral standardization procedure for Raman spectroscopy.
The Analyst 2005;130(8):1204-14.
2005: Krysko D V; Leybaert L; Vandenabeele P; D'Herde K
Gap junctions and the propagation of cell survival and cell death signals.
Apoptosis : an international journal on programmed cell death 2005;10(3):459-69.
2005: Saelens Xavier; Festjens Nele; Parthoens Eef; Vanoverberghe Isabel; Kalai Michael; van Kuppeveld Frank; Vandenabeele Peter
Protein synthesis persists during necrotic cell death.
The Journal of cell biology 2005;168(4):545-51.
2005: Cornelis Sigrid; Bruynooghe Yanik; Van Loo Geert; Saelens Xavier; Vandenabeele Peter; Beyaert Rudi
Apoptosis of hematopoietic cells induced by growth factor withdrawal is associated with caspase-9 mediated cleavage of Raf-1.
Oncogene 2005;24(9):1552-62.
2005: Depuydt Bart; van Loo Geert; Vandenabeele Peter; Declercq Wim
Induction of apoptosis by TNF receptor 2 in a T-cell hybridoma is FADD dependent and blocked by caspase-8 inhibitors.
Journal of cell science 2005;118(Pt 3):497-504.
2005: Lamkanfi Mohamed; D'hondt Kathleen; Vande Walle Lieselotte; van Gurp Marjan; Denecker Geertrui; Demeulemeester Jill; Kalai Michael; Declercq Wim; Saelens Xavier; Vandenabeele Peter
A novel caspase-2 complex containing TRAF2 and RIP1.
The Journal of biological chemistry 2005;280(8):6923-32.
2004: Van Laethem An; Van Kelst Sofie; Lippens Saskia; Declercq Wim; Vandenabeele Peter; Janssens Stefan; Vandenheede Jackie R; Garmyn Maria; Agostinis Patrizia
Activation of p38 MAPK is required for Bax translocation to mitochondria, cytochrome c release and apoptosis induced by UVB irradiation in human keratinocytes.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(15):1946-8.
2004: Lamkanfi Mohamed; Denecker Geertrui; Kalai Michael; D'hondt Kathleen; Meeus Ann; Declercq Wim; Saelens Xavier; Vandenabeele Peter
INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation.
The Journal of biological chemistry 2004;279(50):51729-38.
2004: Hutsebaut D; Maquelin K; De Vos P; Vandenabeele P; Moens L; Puppels G J
Effect of culture conditions on the achievable taxonomic resolution of Raman spectroscopy disclosed by three Bacillus species.
Analytical chemistry 2004;76(21):6274-81.
2004: Lippens Saskia; Kockx Mark; Denecker Geertrui; Knaapen Michiel; Verheyen An; Christiaen Ruben; Tschachler Erwin; Vandenabeele Peter; Declercq Wim
Vitamin D3 induces caspase-14 expression in psoriatic lesions and enhances caspase-14 processing in organotypic skin cultures.
The American journal of pathology 2004;165(3):833-41.
2004: Castro K; Vandenabeele P; Rodríguez-Laso M D; Moens L; Madariaga J M
Micro-Raman analysis of coloured lithographs.
Analytical and bioanalytical chemistry 2004;379(4):674-83.
2004: Vántus Tibor; Vertommen Didier; Saelens Xavier; Rykx An; De Kimpe Line; Vancauwenbergh Sadia; Mikhalap Svitlana; Waelkens Etienne; Kéri György; Seufferlein Thomas; Vandenabeele Peter; Rider Mark H; Vandenheede Jackie R; Van Lint Johan
Doxorubicin-induced activation of protein kinase D1 through caspase-mediated proteolytic cleavage: identification of two cleavage sites by microsequencing.
Cellular signalling 2004;16(6):703-9.
2004: Schotte Peter; Denecker Geertrui; Van Den Broeke Aeke; Vandenabeele Peter; Cornelis Guy R; Beyaert Rudi
Targeting Rac1 by the Yersinia effector protein YopE inhibits caspase-1-mediated maturation and release of interleukin-1beta.
The Journal of biological chemistry 2004;279(24):25134-42.
2004: Lamkanfi Mohamed; Kalai Michael; Saelens Xavier; Declercq Wim; Vandenabeele Peter
Caspase-1 activates nuclear factor of the kappa-enhancer in B cells independently of its enzymatic activity.
The Journal of biological chemistry 2004;279(23):24785-93.
2004: Vandenabeele P; Weis T L; Grant E R; Moens L J
A new instrument adapted to in situ Raman analysis of objects of art.
Analytical and bioanalytical chemistry 2004;379(1):137-42.
2004: Saelens Xavier; Festjens Nele; Vande Walle Lieselotte; van Gurp Maria; van Loo Geert; Vandenabeele Peter
Toxic proteins released from mitochondria in cell death.
Oncogene 2004;23(16):2861-74.
2004: Lamkanfi M; Kalai M; Vandenabeele P
Caspase-12: an overview.
Cell death and differentiation 2004;11(4):365-8.
2004: Brouckaert Greet; Kalai Michael; Krysko Dmitri V; Saelens Xavier; Vercammen Dominique; Ndlovu 'Matladi; Haegeman Guy; D'Herde Katharina; Vandenabeele Peter
Phagocytosis of necrotic cells by macrophages is phosphatidylserine dependent and does not induce inflammatory cytokine production.
Molecular biology of the cell 2004;15(3):1089-100.
2004: Vanderheyde Nathalie; Vandenabeele Peter; Goldman Michel; Willems Fabienne
Distinct mechanisms are involved in tumoristatic and tumoricidal activities of monocyte-derived dendritic cells.
Immunology letters 2004;91(2-3):99-101.
2004: Vanden Berghe Tom; van Loo Geert; Saelens Xavier; Van Gurp Maria; Brouckaert Greet; Kalai Michael; Declercq Wim; Vandenabeele Peter
Differential signaling to apoptotic and necrotic cell death by Fas-associated death domain protein FADD.
The Journal of biological chemistry 2004;279(9):7925-33.
2004: Vanden Berghe Tom; Denecker Geertrui; Brouckaert Greet; Vadimovisch Krysko Dmitri; D'Herde Katharina; Vandenabeele Peter
More than one way to die: methods to determine TNF-induced apoptosis and necrosis.
Methods in molecular medicine 2004;98():101-26.
2004: Festjens Nele; van Gurp Marjan; van Loo Geert; Saelens Xavier; Vandenabeele Peter
Bcl-2 family members as sentinels of cellular integrity and role of mitochondrial intermembrane space proteins in apoptotic cell death.
Acta haematologica 2004;111(1-2):7-27.
2003: Krysko Dmitri V; Brouckaert Greet; Kalai Michael; Vandenabeele Peter; D'Herde Katharina
Mechanisms of internalization of apoptotic and necrotic L929 cells by a macrophage cell line studied by electron microscopy.
Journal of morphology 2003;258(3):336-45.
2003: Jupp Orla J; Vandenabeele Peter; MacEwan David J
Distinct regulation of cytosolic phospholipase A2 phosphorylation, translocation, proteolysis and activation by tumour necrosis factor-receptor subtypes.
The Biochemical journal 2003;374(Pt 2):453-61.
2003: Vandenabeele Peter; Grimaldi Dulce Maria; Edwards Howell G M; Moens Luc
Raman spectroscopy of different types of Mexican copal resins.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2003;59(10):2221-9.
2003: Kalai Michael; Lamkanfi Mohamed; Denecker Geertrui; Boogmans Michael; Lippens Saskia; Meeus Ann; Declercq Wim; Vandenabeele Peter
Regulation of the expression and processing of caspase-12.
The Journal of cell biology 2003;162(3):457-67.
2003: Kahns Soren; Kalai Michael; Jakobsen Lene Diness; Clark Brian F C; Vandenabeele Peter; Jensen Poul Henning
Caspase-1 and caspase-8 cleave and inactivate cellular parkin.
The Journal of biological chemistry 2003;278(26):23376-80.
2003: Lauwaet Tineke; Oliveira Maria José; Callewaert Bert; De Bruyne Georges; Saelens Xavier; Ankri Serge; Vandenabeele Peter; Mirelman David; Mareel Marc; Leroy Ancy
Proteolysis of enteric cell villin by Entamoeba histolytica cysteine proteinases.
The Journal of biological chemistry 2003;278(25):22650-6.
2003: Loo Geert van; Lippens Saskia; Hahne Michel; Matthijssens Filip; Declercq Wim; Saelens Xavier; Vandenabeele Peter
A Bcl-2 transgene expressed in hepatocytes does not protect mice from fulminant liver destruction induced by Fas ligand.
Cytokine 2003;22(3-4):62-70.
2003: van Gurp Maria; Festjens Nele; van Loo Geert; Saelens Xavier; Vandenabeele Peter
Mitochondrial intermembrane proteins in cell death.
Biochemical and biophysical research communications 2003;304(3):487-97.
2003: Malmegrim de Farias K C R; Saelens X; Pruijn G J M; Vandenabeele P; van Venrooij W J
Caspase-mediated cleavage of the U snRNP-associated Sm-F protein during apoptosis.
Cell death and differentiation 2003;10(5):570-9.
2003: Fratelli Maddalena; Minto Manuela; Crespi Andrea; Erba Eugenio; Vandenabeele Peter; Del Soldato Piero; Ghezzi Pietro
Inhibition of nuclear factor-kappaB by a nitro-derivative of flurbiprofen: a possible mechanism for antiinflammatory and antiproliferative effect.
Antioxidants & redox signaling 2003;5(2):229-35.
2003: Assefa Zerihun; Garmyn Marjan; Vantieghem Annelies; Declercq Wim; Vandenabeele Peter; Vandenheede Jackie R; Agostinis Patrizia
Ultraviolet B radiation-induced apoptosis in human keratinocytes: cytosolic activation of procaspase-8 and the role of Bcl-2.
FEBS letters 2003;540(1-3):125-32.
2003: Hunter Irene; Cobban Hannah J; Vandenabeele Peter; MacEwan David J; Nixon Graeme F
Tumor necrosis factor-alpha-induced activation of RhoA in airway smooth muscle cells: role in the Ca2+ sensitization of myosin light chain20 phosphorylation.
Molecular pharmacology 2003;63(3):714-21.
2003: Frame Mhairi J; Tate Rothwelle; Adams David R; Morgan Keith M; Houslay M D; Vandenabeele Peter; Pyne Nigel J
Interaction of caspase-3 with the cyclic GMP binding cyclic GMP specific phosphodiesterase (PDE5a1).
European journal of biochemistry / FEBS 2003;270(5):962-70.
2003: Lippens S; VandenBroecke C; Van Damme E; Tschachler E; Vandenabeele P; Declercq W
Caspase-14 is expressed in the epidermis, the choroid plexus, the retinal pigment epithelium and thymic Hassall's bodies.
Cell death and differentiation 2003;10(2):257-9.
2003: Vandenabeele Peter; Moens Luc
Micro-Raman spectroscopy of natural and synthetic indigo samples.
The Analyst 2003;128(2):187-93.
2003: Vanden Berghe Tom; Kalai Michael; van Loo Geert; Declercq Wim; Vandenabeele Peter
Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis.
The Journal of biological chemistry 2003;278(8):5622-9.
2003: Littlejohn Alison F; Tucker Steven J; Mohamed Ahmed A A; McKay Stephen; Helms Matt J; Vandenabeele Peter; MacEwan David J
Modulation by caspases of tumor necrosis factor-stimulated c-Jun N-terminal kinase activation but not nuclear factor-kappaB signaling.
Biochemical pharmacology 2003;65(1):91-9.
2002: van Loo G; Saelens X; Matthijssens F; Schotte P; Beyaert R; Declercq W; Vandenabeele P
Caspases are not localized in mitochondria during life or death.
Cell death and differentiation 2002;9(11):1207-11.
2002: van Loo G; Saelens X; van Gurp M; MacFarlane M; Martin S J; Vandenabeele P
The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.
Cell death and differentiation 2002;9(10):1031-42.
2002: Kalai M; Van Loo G; Vanden Berghe T; Meeus A; Burm W; Saelens X; Vandenabeele P
Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA.
Cell death and differentiation 2002;9(9):981-94.
2002: Varghese Jishy; Sade Hadassah; Vandenabeele Peter; Sarin Apurva
Head involution defective (Hid)-triggered apoptosis requires caspase-8 but not FADD (Fas-associated death domain) and is regulated by Erk in mammalian cells.
The Journal of biological chemistry 2002;277(38):35097-104.
2002: Mohamed Ahmed A A; Jupp Orla J; Anderson Helen M; Littlejohn Alison F; Vandenabeele Peter; MacEwan David J
Tumour necrosis factor-induced activation of c-Jun N-terminal kinase is sensitive to caspase-dependent modulation while activation of mitogen-activated protein kinase (MAPK) or p38 MAPK is not.
The Biochemical journal 2002;366(Pt 1):145-55.
2002: Storey Helen; Stewart Abigail; Vandenabeele Peter; Luzio J Paul
The p55 tumour necrosis factor receptor TNFR1 contains a trans-Golgi network localization signal in the C-terminal region of its cytoplasmic tail.
The Biochemical journal 2002;366(Pt 1):15-22.
2002: Lamkanfi M; Declercq W; Kalai M; Saelens X; Vandenabeele P
Alice in caspase land. A phylogenetic analysis of caspases from worm to man.
Cell death and differentiation 2002;9(4):358-61.
2002: McFarlane Shona M; Pashmi Ghazaleh; Connell Michelle C; Littlejohn Alison F; Tucker Steven J; Vandenabeele Peter; MacEwan David J
Differential activation of nuclear factor-kappaB by tumour necrosis factor receptor subtypes. TNFR1 predominates whereas TNFR2 activates transcription poorly.
FEBS letters 2002;515(1-3):119-26.
2002: Van Loo G; Demol H; van Gurp M; Hoorelbeke B; Schotte P; Beyaert R; Zhivotovsky B; Gevaert K; Declercq W; Vandekerckhove J; Vandenabeele P
A matrix-assisted laser desorption ionization post-source decay (MALDI-PSD) analysis of proteins released from isolated liver mitochondria treated with recombinant truncated Bid.
Cell death and differentiation 2002;9(3):301-8.
2002: van Loo G; van Gurp M; Depuydt B; Srinivasula S M; Rodriguez I; Alnemri E S; Gevaert K; Vandekerckhove J; Declercq W; Vandenabeele P
The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity.
Cell death and differentiation 2002;9(1):20-6.
2002: Pollock J; McFarlane S M; Connell M C; Zehavi U; Vandenabeele P; MacEwan D J; Scott R H
TNF-alpha receptors simultaneously activate Ca2+ mobilisation and stress kinases in cultured sensory neurones.
Neuropharmacology 2002;42(1):93-106.
2002: Beyaert Rudi; Van Loo Geert; Heyninck Karen; Vandenabeele Peter
Signaling to gene activation and cell death by tumor necrosis factor receptors and Fas.
International review of cytology 2002;214():225-72.
2001: van Loo G; Schotte P; van Gurp M; Demol H; Hoorelbeke B; Gevaert K; Rodriguez I; Ruiz-Carrillo A; Vandekerckhove J; Declercq W; Beyaert R; Vandenabeele P
Endonuclease G: a mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation.
Cell death and differentiation 2001;8(12):1136-42.
2001: Jupp O J; McFarlane S M; Anderson H M; Littlejohn A F; Mohamed A A; MacKay R H; Vandenabeele P; MacEwan D J
Type II tumour necrosis factor-alpha receptor (TNFR2) activates c-Jun N-terminal kinase (JNK) but not mitogen-activated protein kinase (MAPK) or p38 MAPK pathways.
The Biochemical journal 2001;359(Pt 3):525-35.
2001: Saelens X; Kalai M; Vandenabeele P
Translation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-alpha phosphorylation.
The Journal of biological chemistry 2001;276(45):41620-8.
2001: Frame M; Wan K F; Tate R; Vandenabeele P; Pyne N J
The gamma subunit of the rod photoreceptor cGMP phosphodiesterase can modulate the proteolysis of two cGMP binding cGMP-specific phosphodiesterases (PDE6 and PDE5) by caspase-3.
Cellular signalling 2001;13(10):735-41.
2001: Vántus T; Kéri G; Krivickiene Z; Valius M; Steták A; Keppens S; Csermely P; Bauer P I; Bökönyi G; Declercq W; Vandenabeele P; Merlevede W; Vandenheede J R
The somatostatin analogue TT-232 induces apoptosis in A431 cells: sustained activation of stress-activated kinases and inhibition of signalling to extracellular signal-regulated kinases.
Cellular signalling 2001;13(10):717-25.
2001: Vanderheyde N; Aksoy E; Amraoui Z; Vandenabeele P; Goldman M; Willems F
Tumoricidal activity of monocyte-derived dendritic cells: evidence for a caspase-8-dependent, Fas-associated death domain-independent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(7):3565-9.
2001: Ameloot P; Fiers W; De Bleser P; Ware C F; Vandenabeele P; Brouckaert P
Identification of tumor necrosis factor (TNF) amino acids crucial for binding to the murine p75 TNF receptor and construction of receptor-selective mutants.
The Journal of biological chemistry 2001;276(40):37426-30.
2001: Vantieghem A; Xu Y; Declercq W; Vandenabeele P; Denecker G; Vandenheede J R; Merlevede W; de Witte P A; Agostinis P
Different pathways mediate cytochrome c release after photodynamic therapy with hypericin.
Photochemistry and photobiology 2001;74(2):133-42.
2001: Denecker G; Vercammen D; Steemans M; Vanden Berghe T; Brouckaert G; Van Loo G; Zhivotovsky B; Fiers W; Grooten J; Declercq W; Vandenabeele P
Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria.
Cell death and differentiation 2001;8(8):829-40.
2001: Ameloot P; Declercq W; Fiers W; Vandenabeele P; Brouckaert P
Heterotrimers formed by tumor necrosis factors of different species or muteins.
The Journal of biological chemistry 2001;276(29):27098-103.
2001: Schotte P; Van Loo G; Carpentier I; Vandenabeele P; Beyaert R
Lithium sensitizes tumor cells in an NF-kappa B-independent way to caspase activation and apoptosis induced by tumor necrosis factor (TNF). Evidence for a role of the TNF receptor-associated death domain protein.
The Journal of biological chemistry 2001;276(28):25939-45.
2001: Denecker G; Declercq W; Geuijen C A; Boland A; Benabdillah R; van Gurp M; Sory M P; Vandenabeele P; Cornelis G R
Yersinia enterocolitica YopP-induced apoptosis of macrophages involves the apoptotic signaling cascade upstream of bid.
The Journal of biological chemistry 2001;276(23):19706-14.
2001: Denecker G; Vercammen D; Declercq W; Vandenabeele P
Apoptotic and necrotic cell death induced by death domain receptors.
Cellular and molecular life sciences : CMLS 2001;58(3):356-70.
2001: McFarlane S M; Jupp O J; Cobban H J; Hunter I; Anderson H M; Vandenabeele P; Nixon G F; MacEwan D J
Stimulation of stress-activated but not mitogen-activated protein kinases by tumour necrosis factor receptor subtypes in airway smooth muscle.
Biochemical pharmacology 2001;61(6):749-59.
2000: Lippens S; Kockx M; Knaapen M; Mortier L; Polakowska R; Verheyen A; Garmyn M; Zwijsen A; Formstecher P; Huylebroeck D; Vandenabeele P; Declercq W
Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing.
Cell death and differentiation 2000;7(12):1218-24.
2000: Eckhart L; Declercq W; Ban J; Rendl M; Lengauer B; Mayer C; Lippens S; Vandenabeele P; Tschachler E
Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation.
The Journal of investigative dermatology 2000;115(6):1148-51.
2000: Boone E; Vanden Berghe T; Van Loo G; De Wilde G; De Wael N; Vercammen D; Fiers W; Haegeman G; Vandenabeele P
Structure/Function analysis of p55 tumor necrosis factor receptor and fas-associated death domain. Effect on necrosis in L929sA cells.
The Journal of biological chemistry 2000;275(48):37596-603.
2000: Assefa Z; Vantieghem A; Garmyn M; Declercq W; Vandenabeele P; Vandenheede J R; Bouillon R; Merlevede W; Agostinis P
p38 mitogen-activated protein kinase regulates a novel, caspase-independent pathway for the mitochondrial cytochrome c release in ultraviolet B radiation-induced apoptosis.
The Journal of biological chemistry 2000;275(28):21416-21.
2000: Penning L C; Denecker G; Vercammen D; Declercq W; Schipper R G; Vandenabeele P
A role for potassium in TNF-induced apoptosis and gene-induction in human and rodent tumour cell lines.
Cytokine 2000;12(6):747-50.
2000: Pype S; Declercq W; Ibrahimi A; Michiels C; Van Rietschoten J G; Dewulf N; de Boer M; Vandenabeele P; Huylebroeck D; Remacle J E
TTRAP, a novel protein that associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor-associated factors (TRAFs), and that inhibits nuclear factor-kappa B activation.
The Journal of biological chemistry 2000;275(24):18586-93.
2000: Denecker G; Dooms H; Van Loo G; Vercammen D; Grooten J; Fiers W; Declercq W; Vandenabeele P
Phosphatidyl serine exposure during apoptosis precedes release of cytochrome c and decrease in mitochondrial transmembrane potential.
FEBS letters 2000;465(1):47-52.
1999: Fiers W; Beyaert R; Declercq W; Vandenabeele P
More than one way to die: apoptosis, necrosis and reactive oxygen damage.
Oncogene 1999;18(54):7719-30.
1999: Van de Craen M; Declercq W; Van den brande I; Fiers W; Vandenabeele P
The proteolytic procaspase activation network: an in vitro analysis.
Cell death and differentiation 1999;6(11):1117-24.
1999: Van Molle W; Denecker G; Rodriguez I; Brouckaert P; Vandenabeele P; Libert C
Activation of caspases in lethal experimental hepatitis and prevention by acute phase proteins.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(10):5235-41.
1999: Van de Craen M; Berx G; Van den Brande I; Fiers W; Declercq W; Vandenabeele P
Proteolytic cleavage of beta-catenin by caspases: an in vitro analysis.
FEBS letters 1999;458(2):167-70.
1999: Faraco P R; Ledgerwood E C; Vandenabeele P; Prins J B; Bradley J R
Tumor necrosis factor induces distinct patterns of caspase activation in WEHI-164 cells associated with apoptosis or necrosis depending on cell cycle stage.
Biochemical and biophysical research communications 1999;261(2):385-92.
1999: van Criekinge W; Cornelis S; Van De Craen M; Vandenabeele P; Fiers W; Beyaert R
GAL4 is a substrate for caspases: implications for two-hybrid screening and other GAL4-based assays.
Molecular cell biology research communications : MCBRC 1999;1(2):158-61.
1999: Baxter G T; Kuo R C; Jupp O J; Vandenabeele P; MacEwan D J
Tumor necrosis factor-alpha mediates both apoptotic cell death and cell proliferation in a human hematopoietic cell line dependent on mitotic activity and receptor subtype expression.
The Journal of biological chemistry 1999;274(14):9539-47.
1999: Assefa Z; Vantieghem A; Declercq W; Vandenabeele P; Vandenheede J R; Merlevede W; de Witte P; Agostinis P
The activation of the c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signaling pathways protects HeLa cells from apoptosis following photodynamic therapy with hypericin.
The Journal of biological chemistry 1999;274(13):8788-96.
1999: van de Craen M; de Jonghe C; van den Brande I; Declercq W; van Gassen G; van Criekinge W; Vanderhoeven I; Fiers W; van Broeckhoven C; Hendriks L; Vandenabeele P
Identification of caspases that cleave presenilin-1 and presenilin-2. Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases.
FEBS letters 1999;445(1):149-54.
1999: Schotte P; Declercq W; Van Huffel S; Vandenabeele P; Beyaert R
Non-specific effects of methyl ketone peptide inhibitors of caspases.
FEBS letters 1999;442(1):117-21.
1999: Goossens V; De Vos K; Vercammen D; Steemans M; Vancompernolle K; Fiers W; Vandenabeele P; Grooten J
Redox regulation of TNF signaling.
BioFactors (Oxford, England) 1999;10(2-3):145-56.
1998: Prins J B; Ledgerwood E C; Ameloot P; Vandenabeele P; Faraco P R; Bright N A; O'Rahilly S; Bradley J R
Tumor necrosis factor-induced cytotoxicity is not related to rates of mitochondrial morphological abnormalities or autophagy-changes that can be mediated by TNFR-I or TNFR-II.
Bioscience reports 1998;18(6):329-40.
1998: Steemans M; Goossens V; Van de Craen M; Van Herreweghe F; Vancompernolle K; De Vos K; Vandenabeele P; Grooten J
A caspase-activated factor (CAF) induces mitochondrial membrane depolarization and cytochrome c release by a nonproteolytic mechanism.
The Journal of experimental medicine 1998;188(11):2193-8.
1998: Van de Craen M; Van Loo G; Declercq W; Schotte P; Van den brande I; Mandruzzato S; van der Bruggen P; Fiers W; Vandenabeele P
Molecular cloning and identification of murine caspase-8.
Journal of molecular biology 1998;284(4):1017-26.
1998: Prins J; Ledgerwood E; Ameloot P; Vandenabeele P; Faraco P; Bright N; O'Rahilly S; Bradley J
Tumour necrosis factor induced autophagy and mitochondrial morphological abnormalities are mediated by TNFR-I and/or TNFR-II and do not invariably lead to cell death.
Biochemical Society transactions 1998;26(4):S314.
1998: Vantieghem A; Assefa Z; Vandenabeele P; Declercq W; Courtois S; Vandenheede J R; Merlevede W; de Witte P; Agostinis P
Hypericin-induced photosensitization of HeLa cells leads to apoptosis or necrosis. Involvement of cytochrome c and procaspase-3 activation in the mechanism of apoptosis.
FEBS letters 1998;440(1-2):19-24.
1998: Vancompernolle K; Van Herreweghe F; Pynaert G; Van de Craen M; De Vos K; Totty N; Sterling A; Fiers W; Vandenabeele P; Grooten J
Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity.
FEBS letters 1998;438(3):150-8.
1998: Van de Craen M; Van Loo G; Pype S; Van Criekinge W; Van den brande I; Molemans F; Fiers W; Declercq W; Vandenabeele P
Identification of a new caspase homologue: caspase-14.
Cell death and differentiation 1998;5(10):838-46.
1998: Schotte P; Van Criekinge W; Van de Craen M; Van Loo G; Desmedt M; Grooten J; Cornelissen M; De Ridder L; Vandekerckhove J; Fiers W; Vandenabeele P; Beyaert R
Cathepsin B-mediated activation of the proinflammatory caspase-11.
Biochemical and biophysical research communications 1998;251(1):379-87.
1998: Van Criekinge W; van Gurp M; Decoster E; Schotte P; Van de Craen M; Fiers W; Vandenabeele P; Beyaert R
Use of the yeast three-hybrid system as a tool to study caspases.
Analytical biochemistry 1998;263(1):62-6.
1998: Vercammen D; Brouckaert G; Denecker G; Van de Craen M; Declercq W; Fiers W; Vandenabeele P
Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways.
The Journal of experimental medicine 1998;188(5):919-30.
1998: Declercq W; Denecker G; Fiers W; Vandenabeele P
Cooperation of both TNF receptors in inducing apoptosis: involvement of the TNF receptor-associated factor binding domain of the TNF receptor 75.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(1):390-9.
1998: Penning L C; Schipper R G; Vercammen D; Verhofstad A A; Denecker T; Beyaert R; Vandenabeele P
Sensitization of tnf-induced apoptosis with polyamine synthesis inhibitors in different human and murine tumour cell lines.
Cytokine 1998;10(6):423-31.
1998: Vercammen D; Beyaert R; Denecker G; Goossens V; Van Loo G; Declercq W; Grooten J; Fiers W; Vandenabeele P
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.
The Journal of experimental medicine 1998;187(9):1477-85.
1998: De Vos K; Goossens V; Boone E; Vercammen D; Vancompernolle K; Vandenabeele P; Haegeman G; Fiers W; Grooten J
The 55-kDa tumor necrosis factor receptor induces clustering of mitochondria through its membrane-proximal region.
The Journal of biological chemistry 1998;273(16):9673-80.
1997: Vercammen D; Vandenabeele P; Beyaert R; Declercq W; Fiers W
Tumour necrosis factor-induced necrosis versus anti-Fas-induced apoptosis in L929 cells.
Cytokine 1997;9(11):801-8.
1997: Denecker G; Vandenabeele P; Grooten J; Penning L C; Declercq W; Beyaert R; Buurman W A; Fiers W
Differential role of calcium in tumour necrosis factor-mediated apoptosis and secretion of granulocyte-macrophage colony-stimulating factor in a T cell hybridoma.
Cytokine 1997;9(9):631-8.
1997: De Valck D; Heyninck K; Van Criekinge W; Vandenabeele P; Fiers W; Beyaert R
A20 inhibits NF-kappaB activation independently of binding to 14-3-3 proteins.
Biochemical and biophysical research communications 1997;238(2):590-4.
1997: Barge R M; Willemze R; Vandenabeele P; Fiers W; Beyaert R
Differential involvement of caspases in apoptosis of myeloid leukemic cells induced by chemotherapy versus growth factor withdrawal.
FEBS letters 1997;409(2):207-10.
1997: Van de Craen M; Van den Brande I; Declercq W; Irmler M; Beyaert R; Tschopp J; Fiers W; Vandenabeele P
Cleavage of caspase family members by granzyme B: a comparative study in vitro.
European journal of immunology 1997;27(5):1296-9.
1997: Beyaert R; Kidd V J; Cornelis S; Van de Craen M; Denecker G; Lahti J M; Gururajan R; Vandenabeele P; Fiers W
Cleavage of PITSLRE kinases by ICE/CASP-1 and CPP32/CASP-3 during apoptosis induced by tumor necrosis factor.
The Journal of biological chemistry 1997;272(18):11694-7.
1997: Van de Craen M; Vandenabeele P; Declercq W; Van den Brande I; Van Loo G; Molemans F; Schotte P; Van Criekinge W; Beyaert R; Fiers W
Characterization of seven murine caspase family members.
FEBS letters 1997;403(1):61-9.
1996: Van Criekinge W; Beyaert R; Van de Craen M; Vandenabeele P; Schotte P; De Valck D; Fiers W
Functional characterization of the prodomain of interleukin-1beta-converting enzyme.
The Journal of biological chemistry 1996;271(44):27245-8.
1995: Vandenabeele P; Declercq W; Beyaert R; Fiers W
Two tumour necrosis factor receptors: structure and function.
Trends in cell biology 1995;5(10):392-9.
1995: Declercq W; Vandenabeele P; Fiers W
Dimerization of chimeric erythropoietin/75 kDa tumour necrosis factor (TNF) receptors transduces TNF signals: necessity for the 75 kDa-TNF receptor transmembrane domain.
Cytokine 1995;7(7):701-9.
1995: Decoster E; Vanhaesebroeck B; Vandenabeele P; Grooten J; Fiers W
Generation and biological characterization of membrane-bound, uncleavable murine tumor necrosis factor.
The Journal of biological chemistry 1995;270(31):18473-8.
1995: Vercammen D; Vandenabeele P; Declercq W; Van de Craen M; Grooten J; Fiers W
Cytotoxicity in L929 murine fibrosarcoma cells after triggering of transfected human p75 tumour necrosis factor (TNF) receptor is mediated by endogenous murine TNF.
Cytokine 1995;7(5):463-70.
1995: Vandenabeele P; Declercq W; Vanhaesebroeck B; Grooten J; Fiers W
Both TNF receptors are required for TNF-mediated induction of apoptosis in PC60 cells.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(6):2904-13.
1995: Fiers W; Beyaert R; Boone E; Cornelis S; Declercq W; Decoster E; Denecker G; Depuydt B; De Valck D; De Wilde G; Goossens V; Grooten J; Haegeman G; Heyninck K; Penning L; Plaisance S; Vancompernolle K; Van Criekinge W; Vandenabeele P; Vanden Berghe W; Van de Craen M; Vandevoorde V; Vercammen D
TNF-induced intracellular signaling leading to gene induction or to cytotoxicity by necrosis or by apoptosis.
Journal of inflammation 1995;47(1-2):67-75.
1994: Vandenabeele P; Goossens V; Beyaert R; Declercq W; Grooten J; Vanhaesebroeck B; Van de Craen M; Vercammen D; Depuydt B; Denecker G
Functional requirement of the two TNF receptors for induction of apoptosis in PC60 cells and the role of mitochondria in TNF-induced cytotoxicity.
Circulatory shock 1994;44(4):196-200.
1994: Donckier V; Abramowicz D; Bruyns C; Florquin S; Vanderhaeghen M L; Amraoui Z; Dubois C; Vandenabeele P; Goldman M
IFN-gamma prevents Th2 cell-mediated pathology after neonatal injection of semiallogenic spleen cells in mice.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(6):2361-8.
1994: Flamand V; Donckier V; Abramowicz D; Goldman M; Vandenabeele P; Urbain J; Moser M; Leo O
In vivo immunosuppression induced by a weakly mitogenic antibody to mouse CD3: evidence that induction of long-lasting in vivo unresponsiveness requires TcR signaling.
Cellular immunology 1994;157(1):239-48.
1994: Donckier V; Flament V; Gérard C; Abramowicz D; Vandenabeele P; Wissing M; Delvaux A; Fiers W; Leo O; Velu T
Modulation of the release of cytokines and reduction of the shock syndrome induced by anti-CD3 monoclonal antibody in mice by interleukin-10.
Transplantation 1994;57(10):1436-9.
1994: Marchant A; Bruyns C; Vandenabeele P; Ducarme M; Gérard C; Delvaux A; De Groote D; Abramowicz D; Velu T; Goldman M
Interleukin-10 controls interferon-gamma and tumor necrosis factor production during experimental endotoxemia.
European journal of immunology 1994;24(5):1167-71.
1994: Van Ostade X; Vandenabeele P; Tavernier J; Fiers W
Human tumor necrosis factor mutants with preferential binding to and activity on either the R55 or R75 receptor.
European journal of biochemistry / FEBS 1994;220(3):771-9.
1994: Marchant A; Bruyns C; Vandenabeele P; Abramowicz D; Gérard C; Delvaux A; Ghezzi P; Velu T; Goldman M
The protective role of interleukin-10 in endotoxin shock.
Progress in clinical and biological research 1994;388():417-23.
1993: Vandenabeele P; Abramowicz D; Berus D; Van der Heyden J; Grooten J; Donckier V; Hooghe-Peters E L; Goldman M; Fiers W
Increased IL-6 production and IL-6-mediated Ig secretion in murine host-vs-graft disease.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(9):4179-87.
1993: Gérard C; Bruyns C; Marchant A; Abramowicz D; Vandenabeele P; Delvaux A; Fiers W; Goldman M; Velu T
Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia.
The Journal of experimental medicine 1993;177(2):547-50.
1993: Van Ostade X; Vandenabeele P; Everaerdt B; Loetscher H; Gentz R; Brockhaus M; Lesslauer W; Tavernier J; Brouckaert P; Fiers W
Human TNF mutants with selective activity on the p55 receptor.
Nature 1993;361(6409):266-9.
1992: Vandenabeele P; Declercq W; Vercammen D; Van de Craen M; Grooten J; Loetscher H; Brockhaus M; Lesslauer W; Fiers W
Functional characterization of the human tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma.
The Journal of experimental medicine 1992;176(4):1015-24.
1991: Alegre M L; Gastaldello K; Abramowicz D; Kinnaert P; Vereerstraeten P; De Pauw L; Vandenabeele P; Moser M; Leo O; Goldman M
Evidence that pentoxifylline reduces anti-CD3 monoclonal antibody-induced cytokine release syndrome.
Transplantation 1991;52(4):674-9.
1991: Alegre M L; Vandenabeele P; Depierreux M; Florquin S; Deschodt-Lanckman M; Flamand V; Moser M; Leo O; Urbain J; Fiers W
Cytokine release syndrome induced by the 145-2C11 anti-CD3 monoclonal antibody in mice: prevention by high doses of methylprednisolone.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(4):1184-91.
1991: Nortier J; Vandenabeele P; Noël E; Bosseloir Y; Goldman M; Deschodt-Lanckman M
Enzymatic degradation of tumor necrosis factor by activated human neutrophils: role of elastase.
Life sciences 1991;49(25):1879-86.
1990: Vandenabeele P; Declercq W; Libert C; Fiers W
Development of a simple, sensitive and specific bioassay for interleukin-1 based on the proliferation of RPMI 1788 cells. Comparison with other bioassays for IL-1.
Journal of immunological methods 1990;135(1-2):25-32.
1990: Vandenabeele P; Grooten J; Fiers W
IL-4 acts synergistically on the IL-2 response of an autoreactive T-cell clone; synergism correlates with increased intracellular IL-2, but not with a modified IL-2 receptor expression.
Cellular immunology 1990;130(1):79-91.
1990: Abramowicz D; Vandervorst P; Bruyns C; Doutrelepont J M; Vandenabeele P; Goldman M
Persistence of anti-donor allohelper T cells after neonatal induction of allotolerance in mice.
European journal of immunology 1990;20(8):1647-53.
1990: Alegre M; Depierreux M; Florquin S; Najdovski T; Vandenabeele P; Abramowicz D; Leo O; Deschodt-Lanckman M; Goldman M
Acute toxicity of anti-CD3 monoclonal antibody in mice: a model for OKT3 first dose reactions.
Transplantation proceedings 1990;22(4):1920-1.
1990: Alegre M; Vandenabeele P; Flamand V; Moser M; Leo O; Abramowicz D; Urbain J; Fiers W; Goldman M
Hypothermia and hypoglycemia induced by anti-CD3 monoclonal antibody in mice: role of tumor necrosis factor.
European journal of immunology 1990;20(3):707-10.
1990: Vandenabeele P; Guisez Y; Declercq W; Bauw G; Vandekerckhove J; Fiers W
Response of murine cell lines to an IL-1/IL-2-induced factor in a rat/mouse T hybridoma (PC60): differential induction of cytokines by human IL-1 alpha and IL-1 beta and partial amino acid sequence of rat GM-CSF.
Lymphokine research 1990;9(3):381-9.
1988: Vandenabeele P; Jayaram B; Devos R; Shaw A; Fiers W
Interleukin 1 alpha acts as an autocrine growth factor for RPMI 1788, an Epstein-Barr virus-transformed human B cell line.
European journal of immunology 1988;18(7):1027-31.
1987: Fiers W; Beyaert R; Brouckaert P; Everaerdt B; Haegeman G; Suffys P; Tavernier J; Vandenabeele P; Vanhaesebroeck B; Van Ostade X
Gene cloning and structure--function relationship of cytokines such as TNF and interleukins.
Immunology letters 1987;16(3-4):219-26.
1985: Devos R; Jayaram B; Vandenabeele P; Fiers W
Recombinant interleukin 2 induces immunoglobulin secretion in Staphylococcus aureus Cowan strain I activated human B-cells.
Immunology letters 1985;11(2):101-5.

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