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Joke Bouwstra
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44
Gooris, Gert
36
Ponec, Maria
23
Junginger, Hans
13
Danhof, Meindert
11
Weerheim, Arij
10
Boddé, Harry
10
Koerten, Henk
9
Li, Gai Ling
9
Pilgram, Gonneke
9
Rissmann, Robert
8
Pavel, Stan
8
Hennink, Wim
8
Honeywell-Nguyen, Loan
7
Groenink, Wouter
7
Dubbelaar, Frank
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All Publications
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2009: Caussin Julia; Rozema Evelien; Gooris Gert S; Wiechers Johann W; Pavel Stan; Bouwstra Joke A
Hydrophilic and lipophilic moisturizers have similar penetration profiles but different effects on SC water distribution in vivo.
Experimental dermatology 2009;18(11):954-61.
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2009: Groen D; Gooris G S; Bouwstra J A
New insights into the stratum corneum lipid organization by X-ray diffraction analysis.
Biophysical journal 2009;97(8):2242-9.
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2009: Rissmann Robert; Oudshoorn Marion H M; Hennink Wim E; Ponec Maria; Bouwstra Joke A
Skin barrier disruption by acetone: observations in a hairless mouse skin model.
Archives of dermatological research 2009;301(8):609-13.
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2009: Oudshoorn Marion H M; Rissmann Robert; van der Coelen Dennis; Hennink Wim E; Ponec Maria; Bouwstra Joke A
Effect of synthetic vernix biofilms on barrier recovery of damaged mouse skin.
Experimental dermatology 2009;18(8):695-703.
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2009: Ding Z; Van Riet E; Romeijn S; Kersten G F A; Jiskoot W; Bouwstra J A
Immune modulation by adjuvants combined with diphtheria toxoid administered topically in BALB/c mice after microneedle array pretreatment.
Pharmaceutical research 2009;26(7):1635-43.
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2009: Rissmann Robert; Oudshoorn Marion H M; Zwier Raphaël; Ponec Maria; Bouwstra Joke A; Hennink Wim E
Mimicking vernix caseosa--preparation and characterization of synthetic biofilms.
International journal of pharmaceutics 2009;372(1-2):59-65.
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2009: Ding Z; Verbaan F J; Bivas-Benita M; Bungener L; Huckriede A; van den Berg D J; Kersten G; Bouwstra J A
Microneedle arrays for the transcutaneous immunization of diphtheria and influenza in BALB/c mice.
Journal of controlled release : official journal of the Controlled Release Society 2009;136(1):71-8.
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2009: Smijs Threes G M; Pavel Stan; Talebi Mojgan; Bouwstra Joke A
Preclinical studies with 5,10,15-Tris(4-methylpyridinium)-20-phenyl-[21H,23H]-porphine trichloride for the photodynamic treatment of superficial mycoses caused by Trichophyton rubrum.
Photochemistry and photobiology 2009;85(3):733-9.
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2009: Janssens M; Gooris G S; Bouwstra J A
Infrared spectroscopy studies of mixtures prepared with synthetic ceramides varying in head group architecture: coexistence of liquid and crystalline phases.
Biochimica et biophysica acta 2009;1788(3):732-42.
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2009: Rissmann Robert; Gooris Gert; Ponec Maria; Bouwstra Joke
Long periodicity phase in extracted lipids of vernix caseosa obtained with equilibration at physiological temperature.
Chemistry and physics of lipids 2009;158(1):32-8.
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2009: Oudshoorn Marion H M; Rissmann Robert; van der Coelen Dennis; Hennink Wim E; Ponec Maria; Bouwstra Joke A
Development of a murine model to evaluate the effect of vernix caseosa on skin barrier recovery.
Experimental dermatology 2009;18(2):178-84.
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2008: Bal Suzanne M; Caussin Julia; Pavel Stan; Bouwstra Joke A
In vivo assessment of safety of microneedle arrays in human skin.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2008;35(3):193-202.
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2008: Rissmann Robert; Oudshoorn Marion H M; Kocks Elise; Hennink Wim E; Ponec Maria; Bouwstra Joke A
Lanolin-derived lipid mixtures mimic closely the lipid composition and organization of vernix caseosa lipids.
Biochimica et biophysica acta 2008;1778(10):2350-60.
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2008: Groen Daniël; Gooris Gert S; Ponec Maria; Bouwstra Joke A
Two new methods for preparing a unique stratum corneum substitute.
Biochimica et biophysica acta 2008;1778(10):2421-9.
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2008: Ding Zhi; Bivas-Benita Maytal; Hirschberg Hoang; Kersten Gideon F A; Jiskoot Wim; Bouwstra Joke A
Preparation and characterization of diphtheria toxoid-loaded elastic vesicles for transcutaneous immunization.
Journal of drug targeting 2008;16(7):555-63.
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2008: Smijs Threes G M; Mulder Aat A; Pavel Stan; Onderwater Jos J M; Koerten Henk K; Bouwstra Joke A
Morphological changes of the dermatophyte Trichophyton rubrum after photodynamic treatment: a scanning electron microscopy study.
Medical mycology : official publication of the International Society for Human and Animal Mycology 2008;46(4):315-25.
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2008: Caussin Julia; Gooris Gert S; Bouwstra Joke A
FTIR studies show lipophilic moisturizers to interact with stratum corneum lipids, rendering the more densely packed.
Biochimica et biophysica acta 2008;1778(6):1517-24.
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2008: Caussin Julia; Gooris Gert S; Janssens Michelle; Bouwstra Joke A
Lipid organization in human and porcine stratum corneum differs widely, while lipid mixtures with porcine ceramides model human stratum corneum lipid organization very closely.
Biochimica et biophysica acta 2008;1778(6):1472-82.
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2008: Verbaan F J; Bal S M; van den Berg D J; Dijksman J A; van Hecke M; Verpoorten H; van den Berg A; Luttge R; Bouwstra J A
Improved piercing of microneedle arrays in dermatomed human skin by an impact insertion method.
Journal of controlled release : official journal of the Controlled Release Society 2008;128(1):80-8.
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2008: Bouwstra Joke A; Groenink H Wouter W; Kempenaar Joop A; Romeijn Stefan G; Ponec Maria
Water distribution and natural moisturizer factor content in human skin equivalents are regulated by environmental relative humidity.
The Journal of investigative dermatology 2008;128(2):378-88.
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2008: Rissmann Robert; Groenink Hendrik W W; Gooris Gert S; Oudshoorn Marion H M; Hennink Wim E; Ponec Maria; Bouwstra Joke A
Temperature-induced changes in structural and physicochemical properties of vernix caseosa.
The Journal of investigative dermatology 2008;128(2):292-9.
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2007: Caussin Julia; Groenink H W Wouter; de Graaff Anko M; Gooris Gert S; Wiechers Johann W; van Aelst Adriaan C; Bouwstra Joke A
Lipophilic and hydrophilic moisturizers show different actions on human skin as revealed by cryo scanning electron microscopy.
Experimental dermatology 2007;16(11):891-8.
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2007: Oudshoorn Marion H M; Penterman Roel; Rissmann Robert; Bouwstra Joke A; Broer Dirk J; Hennink Wim E
Preparation and characterization of structured hydrogel microparticles based on cross-linked hyperbranched polyglycerol.
Langmuir : the ACS journal of surfaces and colloids 2007;23(23):11819-25.
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2007: Smijs Threes G M; Bouwstra Joke A; Talebi Mojgan; Pavel Stan
Investigation of conditions involved in the susceptibility of the dermatophyte Trichophyton rubrum to photodynamic treatment.
The Journal of antimicrobial chemotherapy 2007;60(4):750-9.
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2007: Gooris G S; Bouwstra J A
Infrared spectroscopic study of stratum corneum model membranes prepared from human ceramides, cholesterol, and fatty acids.
Biophysical journal 2007;92(8):2785-95.
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2007: Smijs Threes G M; Bouwstra Joke A; Schuitmaker Hans J; Talebi M; Pavel Stan
A novel ex vivo skin model to study the susceptibility of the dermatophyte Trichophyton rubrum to photodynamic treatment in different growth phases.
The Journal of antimicrobial chemotherapy 2007;59(3):433-40.
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2007: Verbaan F J; Bal S M; van den Berg D J; Groenink W H H; Verpoorten H; Lüttge R; Bouwstra J A
Assembled microneedle arrays enhance the transport of compounds varying over a large range of molecular weight across human dermatomed skin.
Journal of controlled release : official journal of the Controlled Release Society 2007;117(2):238-45.
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2007: Caussin J; Gooris G S; Groenink H W W; Wiechers J W; Bouwstra J A
Interaction of lipophilic moisturizers on stratum corneum lipid domains in vitro and in vivo.
Skin pharmacology and physiology 2007;20(4):175-86.
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2006: Bouwstra Joke A; Ponec Maria
The skin barrier in healthy and diseased state.
Biochimica et biophysica acta 2006;1758(12):2080-95.
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2006: Oudshoorn Marion H M; Rissmann Robert; Bouwstra Joke A; Hennink Wim E
Synthesis and characterization of hyperbranched polyglycerol hydrogels.
Biomaterials 2006;27(32):5471-9.
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2006: Fatouros D G; Groenink H W M; de Graaff A M; van Aelst A C; Koerten H K; Bouwstra J A
Visualization studies of human skin in vitro/in vivo under the influence of an electrical field.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2006;29(2):160-70.
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2006: Rissmann Robert; Groenink Hendrik W W; Weerheim Arij M; Hoath Steven B; Ponec Maria; Bouwstra Joke A
New insights into ultrastructure, lipid composition and organization of vernix caseosa.
The Journal of investigative dermatology 2006;126(8):1823-33.
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2006: Nugroho Akhmad Kharis; Romeijn Stefan G; Zwier Raphaël; de Vries Jan B; Dijkstra Durk; Wikström Håkan; Della-Pasqua Oscar; Danhof Meindert; Bouwstra Joke A
Pharmacokinetics and pharmacodynamics analysis of transdermal iontophoresis of 5-OH-DPAT in rats: in vitro-in vivo correlation.
Journal of pharmaceutical sciences 2006;95(7):1570-85.
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2006: de Jager Miranda; Groenink Wouter; Bielsa i Guivernau Ruth; Andersson Elin; Angelova Nadezhda; Ponec Maria; Bouwstra Joke
A novel in vitro percutaneous penetration model: evaluation of barrier properties with p-aminobenzoic acid and two of its derivatives.
Pharmaceutical research 2006;23(5):951-60.
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2006: de Jager Miranda; Groenink Wouter; van der Spek Joop; Janmaat Co; Gooris Gert; Ponec Maria; Bouwstra Joke
Preparation and characterization of a stratum corneum substitute for in vitro percutaneous penetration studies.
Biochimica et biophysica acta 2006;1758(5):636-44.
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2006: Loan Honeywell-Nguyen P; Wouter Groenink H W; Bouwstra Joke A
Elastic vesicles as a tool for dermal and transdermal delivery.
Journal of liposome research 2006;16(3):273-80.
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2005: de Jager Miranda W; Gooris Gert S; Ponec Maria; Bouwstra Joke A
Lipid mixtures prepared with well-defined synthetic ceramides closely mimic the unique stratum corneum lipid phase behavior.
Journal of lipid research 2005;46(12):2649-56.
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2005: Grams Ylva Y; Whitehead Lynne; Lamers Gerda; Sturmann Nico; Bouwstra Joke A
On-line diffusion profile of a lipophilic model dye in different depths of a hair follicle in human scalp skin.
The Journal of investigative dermatology 2005;125(4):775-82.
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2005: Li G L; Van Steeg T J; Putter H; Van Der Spek J; Pavel S; Danhof M; Bouwstra J A
Cutaneous side-effects of transdermal iontophoresis with and without surfactant pretreatment: a single-blinded, randomized controlled trial.
The British journal of dermatology 2005;153(2):404-12.
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2005: Nugroho Akhmad Kharis; Della-Pasqua Oscar; Danhof Meindert; Bouwstra Joke A
Compartmental modeling of transdermal iontophoretic transport II: in vivo model derivation and application.
Pharmaceutical research 2005;22(3):335-46.
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2005: Nugroho Akhmad Kharis; Li Li; Dijkstra Durk; Wikström Håkan; Danhof Meindert; Bouwstra Joke A
Transdermal iontophoresis of the dopamine agonist 5-OH-DPAT in human skin in vitro.
Journal of controlled release : official journal of the Controlled Release Society 2005;103(2):393-403.
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2005: Li G L; de Vries J J; van Steeg T J; van den Bussche H; Maas H J; Reeuwijk H J E M; Danhof M; Bouwstra J A; van Laar T
Transdermal iontophoretic delivery of apomorphine in patients improved by surfactant formulation pretreatment.
Journal of controlled release : official journal of the Controlled Release Society 2005;101(1-3):199-208.
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2004: Nugroho Akhmad Kharis; Della Pasqua Oscar; Danhof Meindert; Bouwstra Joke A
Compartmental modeling of transdermal iontophoretic transport: I. In vitro model derivation and application.
Pharmaceutical research 2004;21(11):1974-84.
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2004: de Jager Miranda; Gooris Gert; Ponec Maria; Bouwstra Joke
Acylceramide head group architecture affects lipid organization in synthetic ceramide mixtures.
The Journal of investigative dermatology 2004;123(5):911-6.
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2004: Honeywell-Nguyen P Loan; Gooris Gert S; Bouwstra Joke A
Quantitative assessment of the transport of elastic and rigid vesicle components and a model drug from these vesicle formulations into human skin in vivo.
The Journal of investigative dermatology 2004;123(5):902-10.
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2004: de Jager Miranda W; Gooris Gert S; Dolbnya Igor P; Ponec Maria; Bouwstra Joke A
Modelling the stratum corneum lipid organisation with synthetic lipid mixtures: the importance of synthetic ceramide composition.
Biochimica et biophysica acta 2004;1664(2):132-40.
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2004: Grams Ylva Y; Whitehead Lynne; Cornwell Paul; Bouwstra Joke A
Time and depth resolved visualisation of the diffusion of a lipophilic dye into the hair follicle of fresh unfixed human scalp skin.
Journal of controlled release : official journal of the Controlled Release Society 2004;98(3):367-78.
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2004: Grams Ylva Y; Whitehead Lynne; Cornwell Paul; Bouwstra Joke A
On-line visualization of dye diffusion in fresh unfixed human skin.
Pharmaceutical research 2004;21(5):851-9.
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2004: Nugroho Akhmad Kharis; Li Gai Ling; Danhof Meindert; Bouwstra Joke A
Transdermal iontophoresis of rotigotine across human stratum corneum in vitro: influence of pH and NaCl concentration.
Pharmaceutical research 2004;21(5):844-50.
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2004: de Jager Miranda W; Gooris Gert S; Dolbnya Igor P; Bras Wim; Ponec Maria; Bouwstra Joke A
Novel lipid mixtures based on synthetic ceramides reproduce the unique stratum corneum lipid organization.
Journal of lipid research 2004;45(5):923-32.
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2004: Nugroho Akhmad Kharis; Li Gailing; Grossklaus Arne; Danhof Meindert; Bouwstra Joke A
Transdermal iontophoresis of rotigotine: influence of concentration, temperature and current density in human skin in vitro.
Journal of controlled release : official journal of the Controlled Release Society 2004;96(1):159-67.
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2004: Fatouros Dimitrios G; Bouwstra Joke A
Iontophoretic enhancement of timolol across human dermatomed skin in vitro.
Journal of drug targeting 2004;12(1):19-24.
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2003: Li Gai Ling; Grossklaus Arne; Danhof Meindert; Bouwstra Joke A
Iontophoretic R-apomorphine delivery in combination with surfactant pretreatment: in vitro validation studies.
International journal of pharmaceutics 2003;266(1-2):61-8.
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2003: Honeywell-Nguyen P Loan; Arenja Sonia; Bouwstra Joke A
Skin penetration and mechanisms of action in the delivery of the D2-agonist rotigotine from surfactant-based elastic vesicle formulations.
Pharmaceutical research 2003;20(10):1619-25.
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2003: de Jager M W; Gooris G S; Dolbnya I P; Bras W; Ponec M; Bouwstra J A
The phase behaviour of skin lipid mixtures based on synthetic ceramides.
Chemistry and physics of lipids 2003;124(2):123-34.
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2003: Honeywell-Nguyen P Loan; Wouter Groenink H W; de Graaff Anko M; Bouwstra Joke A
The in vivo transport of elastic vesicles into human skin: effects of occlusion, volume and duration of application.
Journal of controlled release : official journal of the Controlled Release Society 2003;90(2):243-55.
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2003: de Graaff A M; Li G L; van Aelst A C; Bouwstra J A
Combined chemical and electrical enhancement modulates stratum corneum structure.
Journal of controlled release : official journal of the Controlled Release Society 2003;90(1):49-58.
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2003: Bouwstra Joke A; de Graaff Anko; Gooris Gert S; Nijsse Jaap; Wiechers Johann W; van Aelst Adriaan C
Water distribution and related morphology in human stratum corneum at different hydration levels.
The Journal of investigative dermatology 2003;120(5):750-8.
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2003: Li Gai Ling; Danhof Meindert; Frederik Peter M; Bouwstra Joke A
Pretreatment with a water-based surfactant formulation affects transdermal iontophoretic delivery of R-apomorphine in vitro.
Pharmaceutical research 2003;20(4):653-9.
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2003: Grams Ylva Y; Alaruikka Soile; Lashley Lisa; Caussin Julia; Whitehead Lynne; Bouwstra Joke A
Permeant lipophilicity and vehicle composition influence accumulation of dyes in hair follicles of human skin.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2003;18(5):329-36.
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2003: Honeywell-Nguyen P Loan; Bouwstra Joke A
The in vitro transport of pergolide from surfactant-based elastic vesicles through human skin: a suggested mechanism of action.
Journal of controlled release : official journal of the Controlled Release Society 2003;86(1):145-56.
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2003: Bouwstra Joke A; Honeywell-Nguyen P Loan; Gooris Gert S; Ponec Maria
Structure of the skin barrier and its modulation by vesicular formulations.
Progress in lipid research 2003;42(1):1-36.
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2002: Bouwstra J A; Honeywell-Nguyen P L
Skin structure and mode of action of vesicles.
Advanced drug delivery reviews 2002;54 Suppl 1():S41-55.
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2002: Li Gai Ling; van der Geest Ronald; Chanet Laurence; van Zanten Elske; Danhof Meindert; Bouwstra Joke A
In vitro iontophoresis of R-apomorphine across human stratum corneum. Structure-transport relationship of penetration enhancement.
Journal of controlled release : official journal of the Controlled Release Society 2002;84(1-2):49-57.
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2002: Honeywell-Nguyen P Loan; de Graaff Anko M; Groenink H W Wouter; Bouwstra Joke A
The in vivo and in vitro interactions of elastic and rigid vesicles with human skin.
Biochimica et biophysica acta 2002;1573(2):130-40.
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2002: Grams Ylva Y; Bouwstra Joke A
Penetration and distribution of three lipophilic probes in vitro in human skin focusing on the hair follicle.
Journal of controlled release : official journal of the Controlled Release Society 2002;83(2):253-62.
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2002: Honeywell-Nguyen P Loan; Frederik Peter M; Bomans Paul H H; Junginger Hans E; Bouwstra Joke A
Transdermal delivery of pergolide from surfactant-based elastic and rigid vesicles: characterization and in vitro transport studies.
Pharmaceutical research 2002;19(7):991-7.
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2002: Bouwstra Joke A; Pilgram Gonneke S K; Ponec Maja
Does the single gel phase exist in stratum corneum?
The Journal of investigative dermatology 2002;118(5):897-8; author reply 899-901.
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2002: Bouwstra Joke A; Gooris Gert S; Dubbelaar Frank E R; Ponec Maja
Phase behavior of stratum corneum lipid mixtures based on human ceramides: the role of natural and synthetic ceramide 1.
The Journal of investigative dermatology 2002;118(4):606-17.
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2002: Grams Ylva Y; Bouwstra Joke A
A new method to determine the distribution of a fluorophore in scalp skin with focus on hair follicles.
Pharmaceutical research 2002;19(3):350-4.
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2002: Bouwstra Joke A; De Graaff Anko; Groenink Wouter; Honeywell Loan
Elastic vesicles: interaction with human skin and drug transport.
Cellular & molecular biology letters 2002;7(2):222-3.
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2001: Li G L; Danhof M; Bouwstra J A
Effect of elastic liquid-state vesicle on apomorphine iontophoresis transport through human skin in vitro.
Pharmaceutical research 2001;18(11):1627-30.
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2001: Li G L; Danhof M; Bouwstra J A
Lontophoretic delivery of apomorphine in vitro: physicochemic considerations.
Pharmaceutical research 2001;18(11):1509-13.
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2001: Bouwstra J A; Gooris G S; Dubbelaar F E; Ponec M
Phase behavior of lipid mixtures based on human ceramides: coexistence of crystalline and liquid phases.
Journal of lipid research 2001;42(11):1759-70.
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2001: Pilgram G S; Vissers D C; van der Meulen H; Pavel S; Lavrijsen S P; Bouwstra J A; Koerten H K
Aberrant lipid organization in stratum corneum of patients with atopic dermatitis and lamellar ichthyosis.
The Journal of investigative dermatology 2001;117(3):710-7.
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2001: Pechtold L A; Boddé H E; Junginger H E; Koerten H K; Bouwstra J A
X-ray microanalysis of cryopreserved human skin to study the effect of iontophoresis on percutaneous ion transport.
Pharmaceutical research 2001;18(7):1012-7.
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2001: Bouwstra J A; van den Bergh B A; Suhonen M
Topical application of drugs: mechanisms involved in chemical enhancement.
Journal of receptor and signal transduction research 2001;21(2-3):259-86.
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2001: van den Bergh B A; Wertz P W; Junginger H E; Bouwstra J A
Elasticity of vesicles assessed by electron spin resonance, electron microscopy and extrusion measurements.
International journal of pharmaceutics 2001;217(1-2):13-24.
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2001: Pilgram G S; van der Meulen J; Gooris G S; Koerten H K; Bouwstra J A
The influence of two azones and sebaceous lipids on the lateral organization of lipids isolated from human stratum corneum.
Biochimica et biophysica acta 2001;1511(2):244-54.
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2001: Ponec M; Gibbs S; Pilgram G; Boelsma E; Koerten H; Bouwstra J; Mommaas M
Barrier function in reconstructed epidermis and its resemblance to native human skin.
Skin pharmacology and applied skin physiology 2001;14 Suppl 1():63-71.
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2001: Bouwstra J; Pilgram G; Gooris G; Koerten H; Ponec M
New aspects of the skin barrier organization.
Skin pharmacology and applied skin physiology 2001;14 Suppl 1():52-62.
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2000: Ponec M; Boelsma E; Weerheim A; Mulder A; Bouwstra J; Mommaas M
Lipid and ultrastructural characterization of reconstructed skin models.
International journal of pharmaceutics 2000;203(1-2):211-25.
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2000: Pilgram G S; Engelsma-van Pelt A M; Koerten H K; Bouwstra J A
The effect of two azones on the lateral lipid organization of human stratum corneum and its permeability.
Pharmaceutical research 2000;17(7):796-802.
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2000: Grewal B S; Naik A; Irwin W J; Gooris G; de Grauw C J; Gerritsen H G; Bouwstra J A
Transdermal macromolecular delivery: real-time visualization of iontophoretic and chemically enhanced transport using two-photon excitation microscopy.
Pharmaceutical research 2000;17(7):788-95.
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2000: Schreiner V; Gooris G S; Pfeiffer S; Lanzendörfer G; Wenck H; Diembeck W; Proksch E; Bouwstra J
Barrier characteristics of different human skin types investigated with X-ray diffraction, lipid analysis, and electron microscopy imaging.
The Journal of investigative dermatology 2000;114(4):654-60.
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2000: Bouwstra J A; Dubbelaar F E; Gooris G S; Ponec M
The lipid organisation in the skin barrier.
Acta dermato-venereologica. Supplementum 2000;208():23-30.
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1999: Bouwstra J A; Gooris G S; Dubbelaar F E; Ponec M
Cholesterol sulfate and calcium affect stratum corneum lipid organization over a wide temperature range.
Journal of lipid research 1999;40(12):2303-12.
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1999: van den Bergh B A; Bouwstra J A; Junginger H E; Wertz P W
Elasticity of vesicles affects hairless mouse skin structure and permeability.
Journal of controlled release : official journal of the Controlled Release Society 1999;62(3):367-79.
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1999: van den Bergh B A; Vroom J; Gerritsen H; Junginger H E; Bouwstra J A
Interactions of elastic and rigid vesicles with human skin in vitro: electron microscopy and two-photon excitation microscopy.
Biochimica et biophysica acta 1999;1461(1):155-73.
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1999: Pilgram G S; Engelsma-van Pelt A M; Bouwstra J A; Koerten H K
Electron diffraction provides new information on human stratum corneum lipid organization studied in relation to depth and temperature.
The Journal of investigative dermatology 1999;113(3):403-9.
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1999: Bouwstra J A; Dubbelaar F E; Gooris G S; Weerheim A M; Ponec M
The role of ceramide composition in the lipid organisation of the skin barrier.
Biochimica et biophysica acta 1999;1419(2):127-36.
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1998: van Kuijk-Meuwissen M E; Mougin L; Junginger H E; Bouwstra J A
Application of vesicles to rat skin in vivo: a confocal laser scanning microscopy study.
Journal of controlled release : official journal of the Controlled Release Society 1998;56(1-3):189-96.
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1998: Jadoul A; Tanojo H; Préat V; Bouwstra J A; Spies F; Boddé H E
Electroperturbation of human stratum corneum fine structure by high voltage pulses: a freeze-fracture electron microscopy and differential thermal analysis study.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 1998;3(2):153-8.
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1998: Vicanová J; Boyce S T; Harriger M D; Weerheim A M; Bouwstra J A; Ponec M
Stratum corneum lipid composition and structure in cultured skin substitutes is restored to normal after grafting onto athymic mice.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 1998;3(2):114-20.
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1998: Bouwstra J A; Gooris G S; Dubbelaar F E; Weerheim A M; Ponec M
pH, cholesterol sulfate, and fatty acids affect the stratum corneum lipid organization.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 1998;3(2):69-74.
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1998: Pilgram G S; Engelsma-van Pelt A M; Oostergetel G T; Koerten H K; Bouwstra J A
Study on the lipid organization of stratum corneum lipid models by (cryo-) electron diffraction.
Journal of lipid research 1998;39(8):1669-76.
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1998: van Kuijk-Meuwissen M E; Junginger H E; Bouwstra J A
Interactions between liposomes and human skin in vitro, a confocal laser scanning microscopy study.
Biochimica et biophysica acta 1998;1371(1):31-9.
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1998: Meuwissen M E; Janssen J; Cullander C; Junginger H E; Bouwstra J A
A cross-section device to improve visualization of fluorescent probe penetration into the skin by confocal laser scanning microscopy.
Pharmaceutical research 1998;15(2):352-6.
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1998: Pilgram G S; Van Pelt A M; Spies F; Bouwstra J A; Koerten H K
Cryo-electron diffraction as a tool to study local variations in the lipid organization of human stratum corneum.
Journal of microscopy 1998;189(Pt 1):71-8.
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1998: Bouwstra J A; Gooris G S; Dubbelaar F E; Weerheim A M; Ijzerman A P; Ponec M
Role of ceramide 1 in the molecular organization of the stratum corneum lipids.
Journal of lipid research 1998;39(1):186-96.
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1997: Gibbs S; Vicanová J; Bouwstra J; Valstar D; Kempenaar J; Ponec M
Culture of reconstructed epidermis in a defined medium at 33 degrees C shows a delayed epidermal maturation, prolonged lifespan and improved stratum corneum.
Archives of dermatological research 1997;289(10):585-95.
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1997: Ponec M; Weerheim A; Kempenaar J; Mulder A; Gooris G S; Bouwstra J; Mommaas A M
The formation of competent barrier lipids in reconstructed human epidermis requires the presence of vitamin C.
The Journal of investigative dermatology 1997;109(3):348-55.
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1997: Van den Bergh B A; Swartzendruber D C; Bos-Van der Geest A; Hoogstraate J J; Schrijvers A H; Boddé H E; Junginger H E; Bouwstra J A
Development of an optimal protocol for the ultrastructural examination of skin by transmission electron microscopy.
Journal of microscopy 1997;187(Pt 2):125-33.
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1997: Bouwstra J A; Thewalt J; Gooris G S; Kitson N
A model membrane approach to the epidermal permeability barrier: an X-ray diffraction study.
Biochemistry 1997;36(25):7717-25.
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1997: Craane-Van Hinsberg I W; Verhoef J C; Spies F; Bouwstra J A; Gooris G S; Junginger H E; Boddé H E
Electroperturbation of the human skin barrier in vitro: II. Effects on stratum corneum lipid ordering and ultrastructure.
Microscopy research and technique 1997;37(3):200-13.
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1997: Tanojo H; Bouwstra J A; Junginger H E; Boddé H E
In vitro human skin barrier modulation by fatty acids: skin permeation and thermal analysis studies.
Pharmaceutical research 1997;14(1):42-9.
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1996: van der Meulen J; van den Bergh B A; Mulder A A; Mommaas A M; Bouwstra J A; Koerten H K
The use of vibratome sections for the ruthenium tetroxide protocol: a key for optimal visualization of epidermal lipid bilayers of the entire human stratum corneum in transmission electron microscopy.
Journal of microscopy 1996;184(Pt 1):67-70.
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1996: ten Grotenhuis E; Demel R A; Ponec M; Boer D R; van Miltenburg J C; Bouwstra J A
Phase behavior of stratum corneum lipids in mixed Langmuir-Blodgett monolayers.
Biophysical journal 1996;71(3):1389-99.
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1996: Skalko N; Bouwstra J; Spies F; Gregoriadis G
The effect of microfluidization of protein-coated liposomes on protein distribution on the surface of generated small vesicles.
Biochimica et biophysica acta 1996;1301(3):249-54.
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1996: Bouwstra J A; Gooris G S; Cheng K; Weerheim A; Bras W; Ponec M
Phase behavior of isolated skin lipids.
Journal of lipid research 1996;37(5):999-1011.
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1996: Bouwstra J A; Cheng K; Gooris G S; Weerheim A; Ponec M
The role of ceramides 1 and 2 in the stratum corneum lipid organisation.
Biochimica et biophysica acta 1996;1300(3):177-86.
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1996: Van Hal D A; Jeremiasse E; Junginger H E; Spies F; Bouwstra J A
Structure of fully hydrated human stratum corneum: a freeze-fracture electron microscopy study.
The Journal of investigative dermatology 1996;106(1):89-95.
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1995: Lavrijsen A P; Bouwstra J A; Gooris G S; Weerheim A; Boddé H E; Ponec M
Reduced skin barrier function parallels abnormal stratum corneum lipid organization in patients with lamellar ichthyosis.
The Journal of investigative dermatology 1995;105(4):619-24.
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1995: Hofland H E; Bouwstra J A; Boddé H E; Spies F; Junginger H E
Interactions between liposomes and human stratum corneum in vitro: freeze fracture electron microscopical visualization and small angle X-ray scattering studies.
The British journal of dermatology 1995;132(6):853-66.
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1995: Bouwstra J A; Gooris G S; Bras W; Downing D T
Lipid organization in pig stratum corneum.
Journal of lipid research 1995;36(4):685-95.
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1995: Bouwstra J A; Gooris G S; Weerheim A; Kempenaar J; Ponec M
Characterization of stratum corneum structure in reconstructed epidermis by X-ray diffraction.
Journal of lipid research 1995;36(3):496-504.
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1994: Tanojo H; Bouwstra J A; Junginger H E; Boddé H E
Subzero thermal analysis of human stratum corneum.
Pharmaceutical research 1994;11(11):1610-6.
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1994: Bouwstra J A; Gooris G S; van der Spek J A; Lavrijsen S; Bras W
The lipid and protein structure of mouse stratum corneum: a wide and small angle diffraction study.
Biochimica et biophysica acta 1994;1212(2):183-92.
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1994: Hofland H E; van der Geest R; Bodde H E; Junginger H E; Bouwstra J A
Estradiol permeation from nonionic surfactant vesicles through human stratum corneum in vitro.
Pharmaceutical research 1994;11(5):659-64.
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1994: Killian J A; Koorengevel M C; Bouwstra J A; Gooris G; Dowhan W; de Kruijff B
Effect of divalent cations on lipid organization of cardiolipin isolated from Escherichia coli strain AH930.
Biochimica et biophysica acta 1994;1189(2):225-32.
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1993: Peschier L J; Bouwstra J A; de Bleyser J; Junginger H E; Leyte J C
Water mobility and structure in poly[2-hydroxyethylmethacrylate] hydrogels by means of the pulsed field gradient NMR technique.
Biomaterials 1993;14(12):945-52.
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1993: Bouwstra J A; Gooris G S; Bras W; Talsma H
Small angle X-ray scattering: possibilities and limitations in characterization of vesicles.
Chemistry and physics of lipids 1993;64(1-3):83-98.
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1992: Talsma H; Gooris G; v Steenbergen M J; Salomons M A; Bouwstra J; Crommelin D J
The influence of the molar ratio of cholesteryl hemisuccinate/dipalmitoylphosphatidylcholine on 'liposome' formation after lipid film hydration.
Chemistry and physics of lipids 1992;62(2):105-12.
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1992: Lehr C M; Bouwstra J A; Kok W; De Boer A G; Tukker J J; Verhoef J C; Breimer D D; Junginger H E
Effects of the mucoadhesive polymer polycarbophil on the intestinal absorption of a peptide drug in the rat.
The Journal of pharmacy and pharmacology 1992;44(5):402-7.
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1992: Lehr C M; Bouwstra J A; Kok W; Noach A B; de Boer A G; Junginger H E
Bioadhesion by means of specific binding of tomato lectin.
Pharmaceutical research 1992;9(4):547-53.
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1992: Hofland H E; Bouwstra J A; Verhoef J C; Buckton G; Chowdry B Z; Ponec M; Junginger H E
Safety aspects of non-ionic surfactant vesicles: a toxicity study related to the physicochemical characteristics of non-ionic surfactants.
The Journal of pharmacy and pharmacology 1992;44(4):287-94.
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1992: Lehr C M; Bouwstra J A; Boddé H E; Junginger H E
A surface energy analysis of mucoadhesion: contact angle measurements on polycarbophil and pig intestinal mucosa in physiologically relevant fluids.
Pharmaceutical research 1992;9(1):70-5.
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1991: Bouwstra J A; Gooris G S; van der Spek J A; Bras W
Structural investigations of human stratum corneum by small-angle X-ray scattering.
The Journal of investigative dermatology 1991;97(6):1005-12.
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1990: Verhoef J C; Boddé H E; de Boer A G; Bouwstra J A; Junginger H E; Merkus F W; Breimer D D
Transport of peptide and protein drugs across biological membranes.
European journal of drug metabolism and pharmacokinetics 1990;15(2):83-93.
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1988: Roorda W E; Bouwstra J A; de Vries M A; Junginger H E
Thermal behavior of poly hydroxy ethyl methacrylate (pHEMA) hydrogels.
Pharmaceutical research 1988;5(11):722-5.
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1988: Roorda W E; Bouwstra J A; de Vries M A; Junginger H E
Thermal analysis of water in p(HEMA) hydrogels.
Biomaterials 1988;9(6):494-9.
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