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Berlinda Vanloo

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Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequences

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Enzyme Activation

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Tsutomu Oka; Eline Remue; Kris Meerschaert; Berlinda Vanloo; Ciska Boucherie; David Gfeller; Gary D Bader; Sachdev S Sidhu; Joël Vandekerckhove; Jan Gettemans; Marius Sudol
Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling.
Veerle Delanote; Berlinda Vanloo; Marie Catillon; Evelyne Friederich; Joël Vandekerckhove; Jan Gettemans
An alpaca single-domain antibody blocks filopodia formation by obstructing L-plastin-mediated F-actin bundling.
Kris Meerschaert; Moe Phyu Tun; Eline Remue; Ariane De Ganck; Ciska Boucherie; Berlinda Vanloo; Gisèle Degeest; Joël Vandekerckhove; Pascale Zimmermann; Nitin Bhardwaj; Hui Lu; Wonhwa Cho; Jan Gettemans
The PDZ2 domain of zonula occludens-1 and -2 is a phosphoinositide binding domain.

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All Publications

2010: Tsutomu Oka; Eline Remue; Kris Meerschaert; Berlinda Vanloo; Ciska Boucherie; David Gfeller; Gary D Bader; Sachdev S Sidhu; Joël Vandekerckhove; Jan Gettemans; Marius Sudol
Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling.
The Biochemical journal 2010;432(3):461-72.
2010: Veerle Delanote; Berlinda Vanloo; Marie Catillon; Evelyne Friederich; Joël Vandekerckhove; Jan Gettemans
An alpaca single-domain antibody blocks filopodia formation by obstructing L-plastin-mediated F-actin bundling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(1):105-18.
2009: Kris Meerschaert; Moe Phyu Tun; Eline Remue; Ariane De Ganck; Ciska Boucherie; Berlinda Vanloo; Gisèle Degeest; Joël Vandekerckhove; Pascale Zimmermann; Nitin Bhardwaj; Hui Lu; Wonhwa Cho; Jan Gettemans
The PDZ2 domain of zonula occludens-1 and -2 is a phosphoinositide binding domain.
Cellular and molecular life sciences : CMLS 2009;66(24):3951-66.
2009: Stien Dhaese; Klaas Vandepoele; Davy Waterschoot; Berlinda Vanloo; Joël Vandekerckhove; Christophe Ampe; Marleen Van Troys
The mouse thymosin beta15 gene family displays unique complexity and encodes a functional thymosin repeat.
Journal of molecular biology 2009;387(4):809-25.
2008: Katrien Van Impe; Thomas Hubert; Veerle De Corte; Berlinda Vanloo; Ciska Boucherie; Joël Vandekerckhove; Jan Gettemans
A new role for nuclear transport factor 2 and Ran: nuclear import of CapG.
Traffic (Copenhagen, Denmark) 2008;9(5):695-707.
2007: Kris Meerschaert; Erik Bruyneel; Olivier De Wever; Berlinda Vanloo; Ciska Boucherie; Marc Bracke; Joël Vandekerckhove; Jan Gettemans
The tandem PDZ domains of syntenin promote cell invasion.
Experimental cell research 2007;313(9):1790-804.
2005: Sophie Desmaret; Lian Qian; Berlinda Vanloo; Kris Meerschaert; Jozef Van Damme; Johan Grooten; Joël Vandekerckhove; Glenn D Prestwich; Jan Gettemans
Lysophosphatidic acid affinity chromatography reveals pyruvate kinase as a specific LPA-binding protein.
Biological chemistry 2005;386(11):1137-47.
2003: Peter Dubruel; Luc Dekie; Bart Christiaens; Berlinda Vanloo; Maryvonne Rosseneu; Joel Van De Kerckhove; Marjo Mannisto; Arto Urtti; Etienne Schacht
Poly-l-glutamic acid derivatives as multifunctional vectors for gene delivery. Part B. Biological evaluation.
Biomacromolecules 2003;4(5):1177-83.
2003: Peter Dubruel; Bart Christiaens; Berlinda Vanloo; Ken Bracke; Maryvonne Rosseneu; Joël Vandekerckhove; Etienne Schacht
Physicochemical and biological evaluation of cationic polymethacrylates as vectors for gene delivery.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2003;18(3-4):211-20.
2003: Frank Peelman; Christine Labeur; Berlinda Vanloo; Stein Roosbeek; Catherine Devaud; Nicolas Duverger; Patrice DENEFLE; Marie Rosier; Joël Vandekerckhove; Maryvonne Rosseneu
Characterization of the ABCA transporter subfamily: identification of prokaryotic and eukaryotic members, phylogeny and topology.
Journal of molecular biology 2003;325(2):259-74.
2002: Tatyana Sklyarova; Veerle De Corte; Kris Meerschaert; Liesbeth Devriendt; Berlinda Vanloo; Juliet Bailey; Lynnette J Cook; Marc Goethals; Jozef Van Damme; Magda Puype; Joël Vandekerckhove; Jan Gettemans
Fragmin60 encodes an actin-binding protein with a C2 domain and controls actin Thr-203 phosphorylation in Physarum plasmodia and sclerotia.
The Journal of biological chemistry 2002;277(42):39840-9.
2002: Bart Christiaens; Sofie Symoens; Stefan Verheyden; Yves Engelborghs; Alain Joliot; Alain Prochiantz; Joël Vandekerckhove; Maryvonne Rosseneu; Berlinda Vanloo; Stefan Vanderheyden
Tryptophan fluorescence study of the interaction of penetratin peptides with model membranes.
European journal of biochemistry / FEBS 2002;269(12):2918-26.
2001: Frank Peelman; Berlinda Vanloo; JL Verschelde; Christine Labeur; Hans Caster; J Taveirne; Annick Verhee; Nicolas Duverger; Joël Vandekerckhove; Jan Tavernier; Maryvonne Rosseneu
Effect of mutations of N- and C-terminal charged residues on the activity of LCAT.
Journal of lipid research 2001;42(4):471-9.
2001: Stein Roosbeek; Berlinda Vanloo; Nicolas Duverger; Hans Caster; Joke Breyne; I De Beun; H Patel; Joël Vandekerckhove; Carol C Shoulders; Maryvonne Rosseneu; Frank Peelman
Three arginine residues in apolipoprotein A-I are critical for activation of lecithin:cholesterol acyltransferase.
Journal of lipid research 2001;42(1):31-40.
2000: J Read; Timothy A Anderson; PJ Ritchie; Berlinda Vanloo; Joanna Amey; David G Levitt; Maryvonne Rosseneu; James Scott; Carol C Shoulders
A mechanism of membrane neutral lipid acquisition by the microsomal triglyceride transfer protein.
The Journal of biological chemistry 2000;275(39):30372-7.
2000: Bart Christiaens; Berlinda Vanloo; C Gouyette; I Van Vynckt; Hans Caster; J Taveirne; Annick Verhee; Christine Labeur; Frank Peelman; Joël Vandekerckhove; Jan Tavernier; Maryvonne Rosseneu
Headgroup specificity of lecithin cholesterol acyltransferase for monomeric and vesicular phospholipids.
Biochimica et biophysica acta 2000;1486(2-3):321-7.
2000: Berlinda Vanloo; Frank Peelman; K Deschuymere; J Taveirne; Annick Verhee; C Gouyette; Christine Labeur; Joël Vandekerckhove; Jan Tavernier; Maryvonne Rosseneu
Relationship between structure and biochemical phenotype of lecithin:cholesterol acyltransferase (LCAT) mutants causing fish-eye disease.
Journal of lipid research 2000;41(5):752-61.
1999: A Decout; Christine Labeur; Berlinda Vanloo; Marc Goethals; Joël Vandekerckhove; Robert Brasseur; Maryvonne Rosseneu
Contribution of the hydrophobicity gradient to the secondary structure and activity of fusogenic peptides.
Molecular membrane biology 1999;16(3):237-46.
1999: Christopher J Mann; Timothy A Anderson; J Read; S A Chester; G B Harrison; S Köchl; PJ Ritchie; P Bradbury; F S Hussain; Joanna Amey; Berlinda Vanloo; Maryvonne Rosseneu; R Infante; John Hancock; David G Levitt; Leonard J Banaszak; James Scott; Carol C Shoulders
The structure of vitellogenin provides a molecular model for the assembly and secretion of atherogenic lipoproteins.
Journal of molecular biology 1999;285(1):391-408.
1999: Frank Peelman; Berlinda Vanloo; O Perez-Mendez; A Decout; JL Verschelde; Christine Labeur; N Vinaimont; Annick Verhee; Nicolas Duverger; Robert Brasseur; Joël Vandekerckhove; Jan Tavernier; Maryvonne Rosseneu
Characterization of functional residues in the interfacial recognition domain of lecithin cholesterol acyltransferase (LCAT).
Protein engineering 1999;12(1):71-8.
1999: Frank Peelman; JL Verschelde; Berlinda Vanloo; Christophe Ampe; Christine Labeur; Jan Tavernier; Joël Vandekerckhove; Maryvonne Rosseneu
Effects of natural mutations in lecithin:cholesterol acyltransferase on the enzyme structure and activity.
Journal of lipid research 1999;40(1):59-69.
1998: S Nion; L Demoor; Christophe Boutillon; J Luchoomun; Berlinda Vanloo; Catherine Fievet; Graciela Castro; Maryvonne Rosseneu; Jean-Charles Fruchart; Andre Tartar; Véronique Clavey
Branched synthetic peptide constructs mimic cellular binding and efflux of apolipoprotein AI in reconstituted high density lipoproteins.
Atherosclerosis 1998;141(2):227-35.
1998: O Pérez-Méndez; Berlinda Vanloo; A Decout; Marc Goethals; Frank Peelman; Joël Vandekerckhove; Robert Brasseur; Maryvonne Rosseneu
Contribution of the hydrophobicity gradient of an amphipathic peptide to its mode of association with lipids.
European journal of biochemistry / FEBS 1998;256(3):570-9.
1998: Christine Labeur; G Lambert; T Van Cauteren; Nicolas Duverger; Berlinda Vanloo; Jean CHAMBAZ; Joël Vandekerckhove; Graciela Castro; Maryvonne Rosseneu
Displacement of apo A-I from HDL by apo A-II or its C-terminal helix promotes the formation of pre-beta1 migrating particles and decreases LCAT activation.
Atherosclerosis 1998;139(2):351-62.
1998: G Lambert; A Decout; Berlinda Vanloo; D Rouy; Nicolas Duverger; Athina-Despina Kalopissis; Joël Vandekerckhove; Jean CHAMBAZ; Robert Brasseur; Maryvonne Rosseneu
The C-terminal helix of human apolipoprotein AII promotes the fusion of unilamellar liposomes and displaces apolipoprotein AI from high-density lipoproteins.
European journal of biochemistry / FEBS 1998;253(1):328-38.
1998: Frank Peelman; N Vinaimont; Annick Verhee; Berlinda Vanloo; JL Verschelde; Christine Labeur; S Seguret-Mace; Nicolas Duverger; G Hutchinson; Joël Vandekerckhove; Jan Tavernier; Maryvonne Rosseneu
A proposed architecture for lecithin cholesterol acyl transferase (LCAT): identification of the catalytic triad and molecular modeling.
Protein science : a publication of the Protein Society 1998;7(3):587-99.
1997: Thierry Pillot; laurence lins; Marc Goethals; Berlinda Vanloo; J Baert; Joël Vandekerckhove; Maryvonne Rosseneu; Robert Brasseur
The 118-135 peptide of the human prion protein forms amyloid fibrils and induces liposome fusion.
Journal of molecular biology 1997;274(3):381-93.
1997: Frank Peelman; Marc Goethals; Berlinda Vanloo; Christine Labeur; Robert Brasseur; Joël Vandekerckhove; Maryvonne Rosseneu
Structural and functional properties of the 154-171 wild-type and variant peptides of human lecithin-cholesterol acyltransferase.
European journal of biochemistry / FEBS 1997;249(3):708-15.
1997: Alexander Dergunov; J Taveirne; Berlinda Vanloo; Hans Caster; Maryvonne Rosseneu
Structural organization of lipid phase and protein-lipid interface in apolipoprotein-phospholipid recombinants: influence of cholesterol.
Biochimica et biophysica acta 1997;1346(2):131-46.
1997: M De Pauw; Berlinda Vanloo; Alexander Dergunov; A M Devreese; J Baert; Robert Brasseur; Maryvonne Rosseneu
Composition and structural and functional properties of discoidal and spherical phospholipid-apoE3 complexes.
Biochemistry. Biokhimii͡a 1997;62(3):251-63.
1997: Christine Labeur; laurence lins; Berlinda Vanloo; J Baert; Robert Brasseur; Maryvonne Rosseneu
Design of a new class of amphipathic helical peptides for the plasma apolipoproteins that promote cellular cholesterol efflux but do not activate LCAT.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(3):580-8.
1997: Thierry Pillot; Marc Goethals; Berlinda Vanloo; laurence lins; Robert Brasseur; Joël Vandekerckhove; Maryvonne Rosseneu
Specific modulation of the fusogenic properties of the Alzheimer beta-amyloid peptide by apolipoprotein E isoforms.
European journal of biochemistry / FEBS 1997;243(3):650-9.
1996: Thierry Pillot; Marc Goethals; Berlinda Vanloo; C Talussot; Robert Brasseur; Joël Vandekerckhove; Maryvonne Rosseneu; laurence lins
Fusogenic properties of the C-terminal domain of the Alzheimer beta-amyloid peptide.
The Journal of biological chemistry 1996;271(46):28757-65.
1996: L Demoor; C Boutillon; Catherine Fievet; Berlinda Vanloo; J Baert; Maryvonne Rosseneu; Jean-Charles Fruchart; A Tartar
Branched synthetic constructs that mimic the physico-chemical properties of apolipoprotein AI in reconstituted high-density lipoproteins.
European journal of biochemistry / FEBS 1996;239(1):74-84.
1995: Paul Holvoet; Z Zhao; Berlinda Vanloo; R Vos; Els Deridder; A Dhoest; J Taveirne; E Brouwers; E Demarsin; Yves Engelborghs
Phospholipid binding and lecithin-cholesterol acyltransferase activation properties of apolipoprotein A-I mutants.
Biochemistry 1995;34(41):13334-42.
1995: M De Pauw; Berlinda Vanloo; Karl H Weisgraber; Maryvonne Rosseneu
Comparison of lipid-binding and lecithin:cholesterol acyltransferase activation of the amino- and carboxyl-terminal domains of human apolipoprotein E3.
Biochemistry 1995;34(34):10953-66.
1995: laurence lins; R Brasseur; M De Pauw; J P Van Biervliet; J M Ruysschaert; M Rosseneu; Berlinda Vanloo
Helix-helix interactions in reconstituted high-density lipoproteins.
Biochimica et biophysica acta 1995;1258(1):10-8.
1995: Berlinda Vanloo; L Demoor; C Boutillon; laurence lins; Robert Brasseur; J Baert; Jean-Charles Fruchart; A Tartar; Maryvonne Rosseneu
Association of synthetic peptide fragments of human apolipoprotein A-I with phospholipids.
Journal of lipid research 1995;36(8):1686-96.
1994: J Lopez; M Latta; X Collet; Berlinda Vanloo; G Jung; Patrice DENEFLE; M Rosseneu; Jean CHAMBAZ
Purification and characterization of recombinant human apolipoprotein A-II expressed in Escherichia coli.
European journal of biochemistry / FEBS 1994;225(3):1141-50.
1994: Paul Holvoet; G Perez; H Bernar; E Brouwers; Berlinda Vanloo; M Rosseneu; Désiré Collen
Stimulation with a monoclonal antibody (mAb4E4) of scavenger receptor-mediated uptake of chemically modified low density lipoproteins by THP-1-derived macrophages enhances foam cell generation.
The Journal of clinical investigation 1994;93(1):89-98.
1993: J Corijn; Robert DeLeys; Christine Labeur; Berlinda Vanloo; laurence lins; Robert Brasseur; J Baert; Jean-Marie Ruysschaert; Maryvonne Rosseneu
Synthetic model peptides for apolipoproteins. II. Characterization of the discoidal complexes generated between phospholipids and synthetic model peptides for apolipoproteins.
Biochimica et biophysica acta 1993;1170(1):8-16.
1993: Robert Brasseur; Berlinda Vanloo; Robert DeLeys; laurence lins; Christine Labeur; J Taveirne; Jean-Marie Ruysschaert; Maryvonne Rosseneu
Synthetic model peptides for apolipoproteins. I. Design and properties of synthetic model peptides for the amphipathic helices of the plasma apolipoproteins.
Biochimica et biophysica acta 1993;1170(1):1-7.
1993: laurence lins; S Piron; K Conrath; Berlinda Vanloo; Robert Brasseur; Maryvonne Rosseneu; J Baert; Jean-Marie Ruysschaert
Enzymatic hydrolysis of reconstituted dimyristoylphosphatidylcholine-apo A-I complexes.
Biochimica et biophysica acta 1993;1151(2):137-42.
1993: laurence lins; Robert Brasseur; Maryvonne Rosseneu; Berlinda Vanloo; Jean-Marie Ruysschaert
Structure of the apolipoprotein A-IV/lipid discoidal complexes: an attenuated total reflection polarized Fourier transform infrared spectroscopy study.
Biochimica et biophysica acta 1993;1149(2):267-77.
1992: L Vanderyse; A M Devreese; J Baert; Berlinda Vanloo; laurence lins; Jean-Marie Ruysschaert; Maryvonne Rosseneu
Structural and functional properties of apolipoprotein B in chemically modified low density lipoproteins.
Atherosclerosis 1992;97(2-3):187-99.
1992: Berlinda Vanloo; J Taveirne; J Baert; G Lorent; laurence lins; J M Ruyschaert; Maryvonne Rosseneu
LCAT activation properties of apo A-I CNBr fragments and conversion of discoidal complexes into spherical particles.
Biochimica et biophysica acta 1992;1128(2-3):258-66.
1992: R Brasseur; laurence lins; Berlinda Vanloo; J M Ruysschaert; M Rosseneu
Molecular modeling of the amphipathic helices of the plasma apolipoproteins.
Proteins 1992;13(3):246-57.
1991: Berlinda Vanloo; J Morrison; N Fidge; G Lorent; laurence lins; Robert Brasseur; Jean-Marie Ruysschaert; J Baert; Maryvonne Rosseneu
Characterization of the discoidal complexes formed between apoA-I-CNBr fragments and phosphatidylcholine.
Journal of lipid research 1991;32(8):1253-64.
1990: Robert Brasseur; J De Meutter; Berlinda Vanloo; Erik Goormaghtigh; Jean-Marie Ruysschaert; Maryvonne Rosseneu
Mode of assembly of amphipathic helical segments in model high-density lipoproteins.
Biochimica et biophysica acta 1990;1043(3):245-52.
1989: Erik Goormaghtigh; J De Meutter; Berlinda Vanloo; Robert Brasseur; Maryvonne Rosseneu; Jean-Marie Ruysschaert
Evaluation of the secondary structure of apo B-100 in low-density lipoprotein (LDL) by infrared spectroscopy.
Biochimica et biophysica acta 1989;1006(1):147-50.