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Alessandro Vannucchi

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Guido Finazzi; Maria Chiara Finazzi; Giuseppe Fioritoni; Vincenzo Martinelli; Caterina Musolino; Francesco Nobile; Odoardo Maria Olimpieri; Enrico Maria Pogliani; Tiziano Barbui; Giovanni Barosi; Daniela Cilloni; Tim Demuth; Marco Ruggeri; Piera Sivera; Giorgina Specchia; Silvia Di Tollo; Alessandro M Vannucchi; Alessandro Rambaldi
A phase II study of Givinostat in combination with hydroxycarbamide in patients with polycythaemia vera unresponsive to hydroxycarbamide monotherapy.
Vittorio Rosti; Lorenzo Tozzi; Alessandro M Vannucchi; L Villani; Orsetta Zuffardi; Giovanni Barosi; Gaetano Bergamaschi; Elisa Bonetti; Rita Campanelli; Paolo Catarsi; Elena Dallera; Giacomo Fiandrino; Gabriela Fois; Paola Guglielmelli; Marco Lucioni; Umberto Magrini; Margherita Massa; Francesca Novara; Alessandro Pancrazzi; Marco Paulli; Benedetta Peruzzi; Valentina Poletto; Roberta Riboni
Spleen endothelial cells from patients with myelofibrosis harbor the JAK2V617F mutation.
Costanza Bogani; Alberto Bosi; Paola Guglielmelli; Serena Martinelli; Lorenzo Tozzi; Alessandro M Vannucchi; Niccolò Bartalucci
mTOR inhibitors alone and in combination with JAK2 inhibitors effectively inhibit cells of myeloproliferative neoplasms.

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All Publications

2013: Guido Finazzi; Maria Chiara Finazzi; Giuseppe Fioritoni; Vincenzo Martinelli; Caterina Musolino; Francesco Nobile; Odoardo Maria Olimpieri; Enrico Maria Pogliani; Tiziano Barbui; Giovanni Barosi; Daniela Cilloni; Tim Demuth; Marco Ruggeri; Piera Sivera; Giorgina Specchia; Silvia Di Tollo; Alessandro M Vannucchi; Alessandro Rambaldi
A phase II study of Givinostat in combination with hydroxycarbamide in patients with polycythaemia vera unresponsive to hydroxycarbamide monotherapy.
British journal of haematology 2013;161(5):688-94.
2013: Vittorio Rosti; Lorenzo Tozzi; Alessandro M Vannucchi; L Villani; Orsetta Zuffardi; Giovanni Barosi; Gaetano Bergamaschi; Elisa Bonetti; Rita Campanelli; Paolo Catarsi; Elena Dallera; Giacomo Fiandrino; Gabriela Fois; Paola Guglielmelli; Marco Lucioni; Umberto Magrini; Margherita Massa; Francesca Novara; Alessandro Pancrazzi; Marco Paulli; Benedetta Peruzzi; Valentina Poletto; Roberta Riboni
Spleen endothelial cells from patients with myelofibrosis harbor the JAK2V617F mutation.
Blood 2013;121(2):360-8.
2013: Costanza Bogani; Alberto Bosi; Paola Guglielmelli; Serena Martinelli; Lorenzo Tozzi; Alessandro M Vannucchi; Niccolò Bartalucci
mTOR inhibitors alone and in combination with JAK2 inhibitors effectively inhibit cells of myeloproliferative neoplasms.
PloS one 2013;8(1):e54826.
2012: Tiziano Barbui; Irene Bertozzi; Silvia Betti; Veronika Buxhofer-Ausch; Alessandra Carobbio; Valerio De Stefano; Guido Finazzi; Heinz Gisslinger; Francesco Passamonti; Alessandro Rambaldi; Maria Luigia Randi; Francesco Rodeghiero; Marco Ruggeri; Elisa Rumi; Juergen Thiele; Alessandro M Vannucchi; Ayalew Tefferi
Development and validation of an International Prognostic Score of thrombosis in World Health Organization-essential thrombocythemia (IPSET-thrombosis).
Blood 2012;120(26):5128-33; quiz 5252.
2012: Claire Harrison; Alessandro M Vannucchi
Ruxolitinib: a potent and selective Janus kinase 1 and 2 inhibitor in patients with myelofibrosis. An update for clinicians.
Therapeutic advances in hematology 2012;3(6):341-54.
2012: Jelena D Milosevic; Sonja Pavlovic; Daniela Pietra; Ana Puda; Zdenek Racil; Blanka Robesova; Elisa Rumi; Michael Steurer; Alexey Stukalov; Nada Suvajdzic; Dragica Tomin; Natasa Tosic; Alessandro M Vannucchi; Rotraud Wieser; Tiina Berg; Tatiana Burjanivova; Mario Cazzola; Jacques Colinge; Michael Doubek; Dana Dvorakova; Chiara Elena; Bettina Gisslinger; Heinz Gisslinger; Ashot S Harutyunyan; Michael Hofbauer; Thorsten Klampfl; Elisabeth Koller; Luca Malcovati; Robert Kralovics
Clinical significance of genetic aberrations in secondary acute myeloid leukemia.
American journal of hematology 2012;87(11):1010-6.
2012: Anna L Godfrey; Beatriz Bellosillo; Carlos Besses; Fontanet Bijou; Jean-Michel Boiron; Peter J Campbell; Edwin Chen; Konstanze Döhner; Paola Guglielmelli; Claire N Harrison; Eric Lippert; Mary Frances McMullin; Christina A Ortmann; Francesca Pagano; John T Reilly; Yvonne Silber; Frank Stegelmann; Alessandro M Vannucchi; Anthony R Green
JAK2V617F homozygosity arises commonly and recurrently in PV and ET, but PV is characterized by expansion of a dominant homozygous subclone.
Blood 2012;120(13):2704-7.
2012: Francisco Cervantes; Jean-Loup Demory; Brigitte Dupriez; Paola Guglielmelli; Enrica Morra; Francesco Passamonti; John T Reilly; Elisa Roncoroni; Elisa Rumi; Ayalew Tefferi; Alessandro M Vannucchi; Arturo Pereira
Improving survival trends in primary myelofibrosis: an international study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(24):2981-7.
2012: Tiziano Barbui; Irene Bertozzi; Alessandra Carobbio; Guido Finazzi; Naseema Gangat; Bettina Gisslinger; Heinz Gisslinger; Francesco Passamonti; Alessandro Rambaldi; Maria Luigia Randi; Francesco Rodeghiero; Marco Ruggeri; Elisa Rumi; Jürgen Thiele; Alessandro M Vannucchi; Ayalew Tefferi
Disease characteristics and clinical outcome in young adults with essential thrombocythemia versus early/prefibrotic primary myelofibrosis.
Blood 2012;120(3):569-71.
2012: Veronika Buxhofer-Ausch; Alessandra Carobbio; Guido Finazzi; Sophie Frantal; Naseema Gangat; Bettina Gisslinger; Heinz Gisslinger; Hans-Michael Kvasnicka; Leonhard Müllauer; Francesco Passamonti; Maria L Randi; Francesco Rodeghiero; Marco Ruggeri; Elisa Rumi; Ayalew Tefferi; Jürgen Thiele; Alessandro M Vannucchi; Elisabetta Antonioli; Irene Bertozzi; Tiziano Barbui
Leukocytosis as an important risk factor for arterial thrombosis in WHO-defined early/prefibrotic myelofibrosis: an international study of 264 patients.
American journal of hematology 2012;87(7):669-72.
2012: Alessandro M Vannucchi; Lisa Pieri; Maria Chiara Susini; Paola Guglielmelli
BCR-ABL1-negative chronic myeloid neoplasms: an update on management techniques.
Future oncology (London, England) 2012;8(5):575-93.
2012: Elisabetta Antonioli; Michele Baccarani; Tiziano Barbui; Irene Bertozzi; Alberto Bosi; Emma Cacciola; Rossella R Cacciola; Mario Cazzola; Valerio De Stefano; Elena Elli; Guido Finazzi; MariaChiara Finazzi; Paola Guglielmelli; Maria Luigia Randi; Vincenzo Martinelli; Francesco Passamonti; Lisa Pieri; Enrico Pogliani; Alessandro Rambaldi; Francesco Rodeghiero; Elena Rossi; Marco Ruggeri; Elisa Rumi; Alessandro M Vannucchi; Nicola Vianelli; Tommaso Za
Hydroxyurea-related toxicity in 3,411 patients with Ph'-negative MPN.
American journal of hematology 2012;87(5):552-4.
2012: Omar Abdel-Wahab; Tiziano Barbui; Giovanni Barosi; Olivier A Bernard; Kapil Bhalla; Mario Cazzola; John D Crispino; Guido Finazzi; Heinz Gisslinger; Jason Gotlib; Paola Guglielmelli; Vikas Gupta; Ronald Hoffman; Jean-Jacques Kiladjian; Robert Kralovics; Tariq Mughal; Pierre Noel; Olatoyosi Odenike; Animesh Pardanani; Juergen Thiele; Richard A Van Etten; Alessandro M Vannucchi; Ayalew Tefferi
Unraveling the genetic underpinnings of myeloproliferative neoplasms and understanding their effect on disease course and response to therapy: proceedings from the 6th International Post-ASH Symposium.
American journal of hematology 2012;87(5):562-8.
2012: Maria Chiara Susini; Elisabetta Antonioli; Alberto Bosi; Paola Guglielmelli; Giovanna Masala; Domenico Palli; Lisa Pieri; Alessandro M Vannucchi
Risk of second cancers in chronic myeloproliferative neoplasms.
Blood 2012;119(16):3861-2; author reply 3862-3.
2012: G Finazzi; Naseema Gangat; Heinz Gisslinger; F Passamonti; A Rambaldi; Maria Luigia Randi; Francesco Rodeghiero; M Ruggeri; Elisa Rumi; Ayalew Tefferi; J Thiele; Alessandro M Vannucchi; Elisabetta Antonioli; I Bertozzi; Veronika Buxhofer-Ausch; A Carobbio; Tiziano Barbui
Incidence and risk factors for bleeding in 1104 patients with essential thrombocythemia or prefibrotic myelofibrosis diagnosed according to the 2008 WHO criteria.
Leukemia 2012;26(4):716-9.
2012: Stefania Bortoluzzi; Paola Guglielmelli; Rossella Manfredini; Ruggiero Norfo; Alessandro M Vannucchi; Flavia Biamonte; Marta Biasiolo; Andrea Bisognin
Characterization and discovery of novel miRNAs and moRNAs in JAK2V617F-mutated SET2 cells.
Blood 2012;119(13):e120-30.
2012: Tiziano Barbui; Irene Bertozzi; Emanuela Boveri; Alessandra Carobbio; Emanuele D'Amore; Guido Finazzi; Andrea Gianatti; Bettina Gisslinger; Heinz Gisslinger; Filippo Marino; Leonhard Müllauer; Ilaria Nichele; Francesco Passamonti; Lisa Pieri; Alessandro Rambaldi; Maria Luigia Randi; Giada Rotunno; Marco Ruggeri; Elisa Rumi; Jürgen Thiele; Alessandro M Vannucchi; Ayalew Tefferi
Initial bone marrow reticulin fibrosis in polycythemia vera exerts an impact on clinical outcome.
Blood 2012;119(10):2239-41.
2012: Claire Harrison; Deborah S Hunter; Jean-Jacques Kiladjian; Laurent Knoops; Richard Levy; Mari McQuitty; Viktoriya Stalbovskaya; Alessandro M Vannucchi; Roger Waltzman; Haifa-Kathrin Al-Ali; Tiziano Barbui; Francisco Cervantes; Heinz Gisslinger; Giovanni Barosi
JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis.
The New England journal of medicine 2012;366(9):787-98.
2012: Ana Puda; Elisa Rumi; Michael Steurer; Natasa Tosic; Alessandro M Vannucchi; Luca Malcovati; Jelena D Milosevic; Sonja Pavlovic; Lisa Pieri; Daniela Pietra; Tiina Berg; Mario Cazzola; Michael Doubek; Chiara Elena; Bettina Gisslinger; Heinz Gisslinger; Paola Guglielmelli; Ashot S Harutyunyan; Thorsten Klampfl; Robert Kralovics
Frequent deletions of JARID2 in leukemic transformation of chronic myeloid malignancies.
American journal of hematology 2012;87(3):245-50.
2012: Alessandra Carobbio; Guido Finazzi; Naseema Gangat; Heinz Gisslinger; Hans Michael Kvasnicka; Maria Luigia Randi; Francesco Passamonti; Alessandro Rambaldi; Francesco Rodeghiero; Marco Ruggeri; Elisa Rumi; Ayalew Tefferi; Juergen Thiele; Alessandro M Vannucchi; Elisabetta Antonioli; Irene Bertozzi; Veronika Buxhofer-Ausch; Tiziano Barbui
Blood tests may predict early primary myelofibrosis in patients presenting with essential thrombocythemia.
American journal of hematology 2012;87(2):203-4.
2011: Luigi Gugliotta; Alessandra Iurlo; Anna Marina Liberati; Monia Lunghi; Vincenzo Martinelli; Emma Cacciola; Rossella R Cacciola; Anna Candoni; Rosanna Ciancia; Katia Codeluppi; Monica Crugnola; Alberto Grossi; Fausto Palmieri; Ivana Pierri; Potito Rosario Scalzulli; Giorgina Specchia; Alessia Tieghi; Giovanni Tortorella; Emilio Usala; Alessandro M Vannucchi; Nicola Vianelli; Maria Gabriella Mazzucconi
Low impact of cardiovascular adverse events on anagrelide treatment discontinuation in a cohort of 232 patients with essential thrombocythemia.
Leukemia research 2011;35(12):1557-63.
2011: Paola Guglielmelli; Claire Hidalgo-Curtis; Amy V Jones; Margherita Maffioli; Andreas Reiter; Joannah Score; Laura Villani; Nils Winkelman; Katerina Zoi; Giovanni Barosi; Flavia Biamonte; Alberto Bosi; Francisco Cervantes; Nicholas C P Cross; Andrew Duncombe; Thomas Ernst; Tiziana Fanelli; Alessandro M Vannucchi
EZH2 mutational status predicts poor survival in myelofibrosis.
Blood 2011;118(19):5227-34.
2011: Alessandro M Vannucchi; Flavia Biamonte
Epigenetics and mutations in chronic myeloproliferative neoplasms.
Haematologica 2011;96(10):1398-402.
2011: Lisa Pieri; Barbara Scappini; Ambra Spolverini; Francesco Albano; Silvia Birtolo; Alberto Bosi; Carmen Fava; Umberto Occhini; Alessandro M Vannucchi
Concomitant occurrence of BCR-ABL and JAK2V617F mutation.
Blood 2011;118(12):3445-6.
2011: Paola Guglielmelli; Maria Letizia Lupo; Elisa Malevolti; Roberto Marchioli; Arianna Masciulli; Ubaldo Occhini; Alessandro Pancrazzi; Simona Paratore; Lisa Pieri; Alessandro Rambaldi; Maria Chiara Susini; Lorenzo Tozzi; Emilio Usala; Alessandro M Vannucchi; Elisabetta Antonioli; Tiziano Barbui; Giovanni Barosi; Niccolò Bartalucci; Flavia Biamonte; Alberto Bosi; Silvia Caglio; Guido Finazzi; Elisabetta Gattoni; Alberto Grossi
Safety and efficacy of everolimus, a mTOR inhibitor, as single agent in a phase 1/2 study in patients with myelofibrosis.
Blood 2011;118(8):2069-76.
2011: Tiziano Barbui; Irene Bertozzi; Emanuela Boveri; Veronika Buxhofer-Ausch; Alessandra Carobbio; Valentina Carrai; Emanuele S G d'Amore; Naseema Gangat; Andrea Gianatti; Heinz Gisslinger; Curtis A Hanson; Filippo Marino; Leonhard Müllauer; Francesco Passamonti; Maria Luigia Randi; Francesco Rodeghiero; Marco Ruggeri; Elisa Rumi; Juergen Thiele; Alessandro M Vannucchi; Elisabetta Antonioli; Ayalew Tefferi
Survival and disease progression in essential thrombocythemia are significantly influenced by accurate morphologic diagnosis: an international study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(23):3179-84.
2011: Giovanni Barosi; Vittorio Rosti; Alessandro M Vannucchi
Therapeutic approaches in myelofibrosis.
Expert opinion on pharmacotherapy 2011;12(10):1597-611.
2011: Paola Guglielmelli; Ilaria Iacobucci; Giovanni Martinelli; Vanessa Ponziani; Lorenzo Tozzi; Alessandro M Vannucchi; Costanza Bogani; Alberto Bosi
Overexpression of microRNA-16-2 contributes to the abnormal erythropoiesis in polycythemia vera.
Blood 2011;117(25):6923-7.
2011: Ambra Spolverini; Amy V Jones; Andreas Hochhaus; Lisa Pieri; Nicholas C P Cross; Alessandro M Vannucchi
The myeloproliferative neoplasm-associated JAK2 46/1 haplotype is not overrepresented in chronic myelogenous leukemia.
Annals of hematology 2011;90(3):365-6.
2011: Tiziano Barbui; Giovanni Barosi; Gunnar Birgegård; Francisco Cervantes; Guido Finazzi; Martin Griesshammer; Claire Harrison; Hans Carl Hasselbalch; Rudiger Hehlmann; Ronald Hoffman; Jean-Jacques Kiladjian; Nicolaus Kröger; Ruben A Mesa; Mary F McMullin; Animesh Pardanani; Francesco Passamonti; Alessandro M Vannucchi; Andreas Reiter; Richard T Silver; Srdan Verstovsek; Ayalew Tefferi
Philadelphia-negative classical myeloproliferative neoplasms: critical concepts and management recommendations from European LeukemiaNet.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(6):761-70.
2011: Alessandro M Vannucchi; Lisa Pieri; Paola Guglielmelli
JAK2 Allele Burden in the Myeloproliferative Neoplasms: Effects on Phenotype, Prognosis and Change with Treatment.
Therapeutic advances in hematology 2011;2(1):21-32.
2011: Tiziano Barbui; Alessandra Carobbio; Guido Finazzi; Alessandro M Vannucchi; Giovanni Barosi; Elisabetta Antonioli; Paola Guglielmelli; Alessandro Pancrazzi; Silvia Salmoiraghi; Pio Zilio; Cosimo Ottomano; Roberto Marchioli; Ivan Cuccovillo; Barbara Bottazzi; Alberto Mantovani; Alessandro Rambaldi
Inflammation and thrombosis in essential thrombocythemia and polycythemia vera: different role of C-reactive protein and pentraxin 3.
Haematologica 2011;96(2):315-8.
2010: Alessandro M Vannucchi; Paola Guglielmelli
Advances in understanding and management of polycythemia vera.
Current opinion in oncology 2010;22(6):636-41.
2010: Maria Verrucci; Alessandro Pancrazzi; Miguel Aracil; Fabrizio Martelli; Paola Guglielmelli; Maria Zingariello; Barbara Ghinassi; Emanuela D'Amore; José Jimeno; Alessandro M Vannucchi; Anna Rita Migliaccio
CXCR4-independent rescue of the myeloproliferative defect of the Gata1low myelofibrosis mouse model by Aplidin.
Journal of cellular physiology 2010;225(2):490-9.
2010: Alessandro M Vannucchi
From palliation to targeted therapy in myelofibrosis.
The New England journal of medicine 2010;363(12):1180-2.
2010: Paola Guglielmelli; F Biamonte; A Spolverini; L Pieri; A Isgrò; Elisabetta Antonioli; Alessandro Pancrazzi; Alberto Bosi; Giovanni Barosi; Alessandro M Vannucchi
Frequency and clinical correlates of JAK2 46/1 (GGCC) haplotype in primary myelofibrosis.
Leukemia 2010;24(8):1533-7.
2010: Elisabetta Antonioli; Alessandra Carobbio; Lisa Pieri; Alessandro Pancrazzi; Paola Guglielmelli; Federica Delaini; Vanessa Ponziani; Niccolò Bartalucci; Lorenzo Tozzi; Alberto Bosi; Alessandro Rambaldi; Tiziano Barbui; Alessandro M Vannucchi
Hydroxyurea does not appreciably reduce JAK2 V617F allele burden in patients with polycythemia vera or essential thrombocythemia.
Haematologica 2010;95(8):1435-8.
2010: Lisa Pieri; Alberto Bosi; Alessandro M Vannucchi
Imatinib and cardiac failure in idiopathic hypereosinophilic syndrome.
Annals of hematology 2010;89(7):745-6.
2010: Alessandro M Vannucchi
Insights into the pathogenesis and management of thrombosis in polycythemia vera and essential thrombocythemia.
Internal and emergency medicine 2010;5(3):177-84.
2010: Giacomo Gianfaldoni; Francesco Mannelli; Vanessa Ponziani; Giovanni Longo; Sara Bencini; Alberto Bosi; Alessandro M Vannucchi
Early reduction of WT1 transcripts during induction chemotherapy predicts for longer disease free and overall survival in acute myeloid leukemia.
Haematologica 2010;95(5):833-6.
2010: Valerio De Stefano; Tommaso Za; Elena Rossi; Alessandro M Vannucchi; Marco Ruggeri; Elena Elli; Caterina Micò; Alessia Tieghi; Rossella R Cacciola; Cristina Santoro; Giancarla Gerli; Paola Guglielmelli; Lisa Pieri; Francesca Scognamiglio; Francesco Rodeghiero; Enrico Pogliani; Guido Finazzi; Luigi Gugliotta; Giuseppe Leone; Tiziano Barbui
Leukocytosis is a risk factor for recurrent arterial thrombosis in young patients with polycythemia vera and essential thrombocythemia.
American journal of hematology 2010;85(2):97-100.
2010: Valerio De Stefano; Tommaso Za; Elena Rossi; Alessandro M Vannucchi; Marco Ruggeri; Elena Elli; Caterina Micò; Alessia Tieghi; Rossella R Cacciola; Cristina Santoro; Nicola Vianelli; Paola Guglielmelli; Lisa Pieri; Francesca Scognamiglio; Emma Cacciola; Francesco Rodeghiero; Enrico M Pogliani; Guido Finazzi; Luigi Gugliotta; Giuseppe Leone; Tiziano Barbui
Increased risk of recurrent thrombosis in patients with essential thrombocythemia carrying the homozygous JAK2 V617F mutation.
Annals of hematology 2010;89(2):141-6.
2010: Tiziano Barbui; Alessandra Carobbio; Francisco Cervantes; Alessandro M Vannucchi; Paola Guglielmelli; Elisabetta Antonioli; Alberto Alvarez-Larrán; Alessandro Rambaldi; Guido Finazzi; Giovanni Barosi
Thrombosis in primary myelofibrosis: incidence and risk factors.
Blood 2010;115(4):778-82.
2010: Lisa Pieri; Paola Guglielmelli; Alessandro M Vannucchi
Chronic myeloproliferative neoplasms: a collaborative approach.
Mediterranean journal of hematology and infectious diseases 2010;2(2):e2010017.
2010: Vittorio Rosti; Elisa Bonetti; Gaetano Bergamaschi; Rita Campanelli; Paola Guglielmelli; Marcello Maestri; Umberto Magrini; Margherita Massa; Carmine Tinelli; Gianluca Viarengo; L Villani; Massimo Primignani; Alessandro M Vannucchi; Francesco Frassoni; Giovanni Barosi
High frequency of endothelial colony forming cells marks a non-active myeloproliferative neoplasm with high risk of splanchnic vein thrombosis.
PloS one 2010;5(12):e15277.
2010: Paola Guglielmelli; Alessandro M Vannucchi
Recent advances in diagnosis and treatment of chronic myeloproliferative neoplasms.
F1000 medicine reports 2010;2():.
2010: Alessandro M Vannucchi
JAK2 mutation and thrombosis in the myeloproliferative neoplasms.
Current hematologic malignancy reports 2010;5(1):22-8.
2009: Alessandro M Vannucchi
How do JAK2-inhibitors work in myelofibrosis: an alternative hypothesis.
Leukemia research 2009;33(12):1581-3.
2009: Lisa Pieri; Costanza Bogani; Paola Guglielmelli; Maria Zingariello; Rosa Alba Rana; Niccolò Bartalucci; Alberto Bosi; Alessandro M Vannucchi
The JAK2V617 mutation induces constitutive activation and agonist hypersensitivity in basophils from patients with polycythemia vera.
Haematologica 2009;94(11):1537-45.
2009: Cristina Cellai; Anna Laurenzana; Elisa Bianchi; Sara Sdelci; Rossella Manfredini; Alessandro M Vannucchi; Roberto Caporale; Manjola Balliu; Francesco Mannelli; Sergio Ferrari; Alberto Bosi; Debora Miniati; Pier L Cocco; Steeve Veronneau; Jana Stankova; Francesco Paoletti
Mechanistic insight into WEB-2170-induced apoptosis in human acute myelogenous leukemia cells: the crucial role of PTEN.
Experimental hematology 2009;37(10):1176-1185.e21.
2009: Alessandra Carobbio; Guido Finazzi; Elisabetta Antonioli; Paola Guglielmelli; Alessandro M Vannucchi; Chiara M Dellacasa; Silvia Salmoiraghi; Federica Delaini; Alessandro Rambaldi; Tiziano Barbui
JAK2V617F allele burden and thrombosis: a direct comparison in essential thrombocythemia and polycythemia vera.
Experimental hematology 2009;37(9):1016-21.
2009: Barbara Ghinassi; Maria Zingariello; Fabrizio Martelli; Rodolfo Lorenzini; Alessandro M Vannucchi; Rosa Alba Rana; Mitsuo Nishikawa; Giovanni Migliaccio; John Mascarenhas; Anna Rita Migliaccio
Increased differentiation of dermal mast cells in mice lacking the Mpl gene.
Stem cells and development 2009;18(7):1081-92.
2009: Paola Guglielmelli; Giovanni Barosi; Giorgina Specchia; Alessandro Rambaldi; Francesco Lo Coco; Elisabetta Antonioli; Lisa Pieri; Alessandro Pancrazzi; Vanessa Ponziani; Federica Delaini; Giovanni Longo; Emanuele Ammatuna; Vincenzo Liso; Alberto Bosi; Tiziano Barbui; Alessandro M Vannucchi
Identification of patients with poorer survival in primary myelofibrosis based on the burden of JAK2V617F mutated allele.
Blood 2009;114(8):1477-83.
2009: Alessandro M Vannucchi; Paola Guglielmelli; Alessandro Rambaldi; Costanza Bogani; Tiziano Barbui
Epigenetic therapy in myeloproliferative neoplasms: evidence and perspectives.
Journal of cellular and molecular medicine 2009;13(8A):1437-50.
2009: Alessandro M Vannucchi; Giovanna Masala; Elisabetta Antonioli; Maria Chiara Susini; Paola Guglielmelli; Lisa Pieri; Laura Maggi; Saverio Caini; Domenico Palli; Costanza Bogani; Vanessa Ponziani; Alessandro Pancrazzi; Francesco Annunziato; Alberto Bosi
Increased risk of lymphoid neoplasms in patients with Philadelphia chromosome-negative myeloproliferative neoplasms.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(7):2068-73.
2009: Paola Guglielmelli; Cinzia Fatini; Meri Lenti; Alberto Bosi; Alessandro M Vannucchi
JAK2V617F mutation screening in patients with retinal vein thrombosis or recurrent fetal loss.
Thrombosis research 2009;124(3):377-8.
2009: Giovanni Barosi; Gunnar Birgegård; Guido Finazzi; Martin Griesshammer; Claire Harrison; Hans Carl Hasselbalch; Jean-Jacques Kiladjian; Eva Lengfelder; Mary Frances McMullin; Francesco Passamonti; John T Reilly; Alessandro M Vannucchi; Tiziano Barbui
Response criteria for essential thrombocythemia and polycythemia vera: result of a European LeukemiaNet consensus conference.
Blood 2009;113(20):4829-33.
2009: Alessandro M Vannucchi; Paola Guglielmelli; Ayalew Tefferi
Advances in understanding and management of myeloproliferative neoplasms.
CA: a cancer journal for clinicians 2009;59(3):171-91.
2009: Lucia Catani; Roberta Zini; D Sollazzo; Emanuela Ottaviani; Alessandro M Vannucchi; Sergio Ferrari; Michele Baccarani; Nicola Vianelli; Roberto M Lemoli; Rossella Manfredini
Molecular profile of CD34+ stem/progenitor cells according to JAK2V617F mutation status in essential thrombocythemia.
Leukemia 2009;23(5):997-1000.
2009: Alessandro M Vannucchi; Paola Guglielmelli; Lisa Pieri; Elisabetta Antonioli; Alberto Bosi
Treatment options for essential thrombocythemia and polycythemia vera.
Expert review of hematology 2009;2(1):41-55.
2008: Alessandra Carobbio; Guido Finazzi; Elisabetta Antonioli; Paola Guglielmelli; Alessandro M Vannucchi; Federica Delaini; Vittoria Guerini; Marco Ruggeri; Francesco Rodeghiero; Alessandro Rambaldi; Tiziano Barbui
Thrombocytosis and leukocytosis interaction in vascular complications of essential thrombocythemia.
Blood 2008;112(8):3135-7.
2008: Alessandro Pancrazzi; Paola Guglielmelli; Vanessa Ponziani; Gaetano Bergamaschi; Alberto Bosi; Giovanni Barosi; Alessandro M Vannucchi
A sensitive detection method for MPLW515L or MPLW515K mutation in chronic myeloproliferative disorders with locked nucleic acid-modified probes and real-time polymerase chain reaction.
The Journal of molecular diagnostics : JMD 2008;10(5):435-41.
2008: Alessandro M Vannucchi; Elisabetta Antonioli; Paola Guglielmelli; Alessandro Pancrazzi; Vittoria Guerini; Giovanni Barosi; Marco Ruggeri; Giorgina Specchia; Francesco Lo Coco; Federica Delaini; Laura Villani; Silvia Finotto; Emanuele Ammatuna; Renato Alterini; Valentina Carrai; Gloria Capaccioli; Simonetta Di Lollo; Vincenzo Liso; Alessandro Rambaldi; Alberto Bosi; Tiziano Barbui
Characteristics and clinical correlates of MPL 515W>L/K mutation in essential thrombocythemia.
Blood 2008;112(3):844-7.
2008: Costanza Bogani; Vanessa Ponziani; Paola Guglielmelli; desterke christophe; Vittorio Rosti; Alberto Bosi; Marie-Caroline Le Bousse-Kerdilès; Giovanni Barosi; Alessandro M Vannucchi
Hypermethylation of CXCR4 promoter in CD34+ cells from patients with primary myelofibrosis.
Stem cells (Dayton, Ohio) 2008;26(8):1920-30.
2008: Alessandro M Vannucchi; Paola Guglielmelli
Molecular pathophysiology of Philadelphia-negative myeloproliferative disorders: beyond JAK2 and MPL mutations.
Haematologica 2008;93(7):972-6.
2008: Alessandra Carobbio; Elisabetta Antonioli; Paola Guglielmelli; Alessandro M Vannucchi; Federica Delaini; Vittoria Guerini; Guido Finazzi; Alessandro Rambaldi; Tiziano Barbui
Leukocytosis and risk stratification assessment in essential thrombocythemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(16):2732-6.
2008: Fabrizio Martelli; Barbara Ghinassi; Rodolfo Lorenzini; Alessandro M Vannucchi; Rosa Alba Rana; Mitsuo Nishikawa; Sandra Partamian; Giovanni Migliaccio; Anna Rita Migliaccio
Thrombopoietin inhibits murine mast cell differentiation.
Stem cells (Dayton, Ohio) 2008;26(4):912-9.
2008: Valerio De Stefano; Tommaso Za; Elena Rossi; Alessandro M Vannucchi; Marco Ruggeri; Elena Elli; Caterina Micò; Alessia Tieghi; Rossella R Cacciola; Cristina Santoro; Giancarla Gerli; Nicola Vianelli; Paola Guglielmelli; Lisa Pieri; Francesca Scognamiglio; Francesco Rodeghiero; Enrico Pogliani; Guido Finazzi; Luigi Gugliotta; Roberto Marchioli; Giuseppe Leone; Tiziano Barbui
Recurrent thrombosis in patients with polycythemia vera and essential thrombocythemia: incidence, risk factors, and effect of treatments.
Haematologica 2008;93(3):372-80.
2008: Lisa Pieri; Paola Guglielmelli; Costanza Bogani; Alberto Bosi; Alessandro M Vannucchi
Mesenchymal stem cells from JAK2(V617F) mutant patients with primary myelofibrosis do not harbor JAK2 mutant allele.
Leukemia research 2008;32(3):516-7.
2008: Anna Rita Migliaccio; Fabrizio Martelli; Maria Verrucci; Giovanni Migliaccio; Alessandro M Vannucchi; Hongyu Ni; Mingjiang Xu; Yi Jiang; Betty Nakamoto; Thalia Papayannopoulou; Ronald Hoffman
Altered SDF-1/CXCR4 axis in patients with primary myelofibrosis and in the Gata1 low mouse model of the disease.
Experimental hematology 2008;36(2):158-71.
2008: Marco Ruggeri; Francesco Rodeghiero; Alberto Tosetto; Giancarlo Castaman; Francesca Scognamiglio; Guido Finazzi; Federica Delaini; Caterina Micò; Alessandro M Vannucchi; Elisabetta Antonioli; Valerio De Stefano; Tommaso Za; Luigi Gugliotta; Alessia Tieghi; Maria Gabriella Mazzucconi; Cristina Santoro; Tiziano Barbui
Postsurgery outcomes in patients with polycythemia vera and essential thrombocythemia: a retrospective survey.
Blood 2008;111(2):666-71.
2008: Elisabetta Antonioli; Paola Guglielmelli; Giada Poli; Costanza Bogani; Alessandro Pancrazzi; Giovanni Longo; Vanessa Ponziani; Lorenzo Tozzi; Lisa Pieri; Valeria Santini; Alberto Bosi; Alessandro M Vannucchi
Influence of JAK2V617F allele burden on phenotype in essential thrombocythemia.
Haematologica 2008;93(1):41-8.
2007: Elisabetta Antonioli; Paola Guglielmelli; Giada Poli; Valeria Santini; Alberto Bosi; Alessandro M Vannucchi
Polycythemia vera following autologous transplantation for AML: insights on the kinetics of JAK2V617F clonal dominance.
Blood 2007;110(13):4620-1.
2007: Giovanni Barosi; Gaetano Bergamaschi; Monia Marchetti; Alessandro M Vannucchi; Paola Guglielmelli; Elisabetta Antonioli; Margherita Massa; Vittorio Rosti; Rita Campanelli; Laura Villani; Gianluca Viarengo; Elisabetta Gattoni; Giancarla Gerli; Giorgina Specchia; Carmine Tinelli; Alessandro Rambaldi; Tiziano Barbui
JAK2 V617F mutational status predicts progression to large splenomegaly and leukemic transformation in primary myelofibrosis.
Blood 2007;110(12):4030-6.
2007: Paola Guglielmelli; Lorenzo Tozzi; Alessandro Pancrazzi; Costanza Bogani; Elisabetta Antonioli; Vanessa Ponziani; Giada Poli; Roberta Zini; Sergio Ferrari; Rossella Manfredini; Alberto Bosi; Alessandro M Vannucchi
MicroRNA expression profile in granulocytes from primary myelofibrosis patients.
Experimental hematology 2007;35(11):1708-18.
2007: Alessandro M Vannucchi; Stefano Guidi; Paola Guglielmelli; S Glinz; L Lombardini; Alessandro Busca; F Locatelli; Anna Maria Dall'Omo; Alberto Bosi
Significance of CTLA-4 and CD14 genetic polymorphisms in clinical outcome after allogeneic stem cell transplantation.
Bone marrow transplantation 2007;40(10):1001-2.
2007: Monica Bocchia; Alessandro M Vannucchi; Alessandro Gozzetti; Paola Guglielmelli; Giada Poli; Rosaria Crupi; Marzia Defina; Alberto Bosi; Lauria Francesco
Insights into JAK2-V617F mutation in CML.
The lancet oncology 2007;8(10):864-6.
2007: Alessandro M Vannucchi; Elisabetta Antonioli; Paola Guglielmelli; Giovanni Longo; Alessandro Pancrazzi; Vanessa Ponziani; Costanza Bogani; Pierluigi Rossi Ferrini; Alessandro Rambaldi; Vittoria Guerini; Alberto Bosi; Tiziano Barbui
Prospective identification of high-risk polycythemia vera patients based on JAK2(V617F) allele burden.
Leukemia 2007;21(9):1952-9.
2007: Alessandro M Vannucchi; Elisabetta Antonioli; Paola Guglielmelli; Alessandro Rambaldi; Giovanni Barosi; Roberto Marchioli; Rosa Maria Marfisi; Guido Finazzi; Vittoria Guerini; Fabrizio Fabris; Maria Luigia Randi; Valerio De Stefano; Sabrina Caberlon; Agostino Tafuri; Marco Ruggeri; Giorgina Specchia; Vincenzo Liso; Edoardo Rossi; Enrico Pogliani; Luigi Gugliotta; Alberto Bosi; Tiziano Barbui
Clinical profile of homozygous JAK2 617V>F mutation in patients with polycythemia vera or essential thrombocythemia.
Blood 2007;110(3):840-6.
2007: Anna Rita Migliaccio; Rosa Alba Rana; Alessandro M Vannucchi; Francesco Antonio Manzoli
Role of thrombopoietin in mast cell differentiation.
Annals of the New York Academy of Sciences 2007;1106():152-74.
2007: Eva Zetterberg; Alessandro M Vannucchi; Anna Rita Migliaccio; William Vainchenker; Micheline Tulliez; Renée Dickie; Hans Carl Hasselbalch; Rick Rogers; Jan Palmblad
Pericyte coverage of abnormal blood vessels in myelofibrotic bone marrows.
Haematologica 2007;92(5):597-604.
2007: Paola Guglielmelli; Alessandro Pancrazzi; Gaetano Bergamaschi; Vittorio Rosti; Laura Villani; Elisabetta Antonioli; Alberto Bosi; Giovanni Barosi; Alessandro M Vannucchi
Anaemia characterises patients with myelofibrosis harbouring Mpl mutation.
British journal of haematology 2007;137(3):244-7.
2007: Vittorio Rosti; Margherita Massa; Alessandro M Vannucchi; Gaetano Bergamaschi; Rita Campanelli; Alessandro Pecci; Gianluca Viarengo; Valentina Meli; Monia Marchetti; Paola Guglielmelli; Edward Bruno; Mingjiang Xu; Ronald Hoffman; Giovanni Barosi
The expression of CXCR4 is down-regulated on the CD34+ cells of patients with myelofibrosis with myeloid metaplasia.
Blood cells, molecules & diseases 2007;38(3):280-6.
2007: Barbara Ghinassi; Massimo Sanchez; Fabrizio Martelli; Giovanni Amabile; Alessandro M Vannucchi; Giovanni Migliaccio; Stuart H Orkin; Anna Rita Migliaccio
The hypomorphic Gata1low mutation alters the proliferation/differentiation potential of the common megakaryocytic-erythroid progenitor.
Blood 2007;109(4):1460-71.
2007: Costanza Bogani; Paola Guglielmelli; Elisabetta Antonioli; Alessandro Pancrazzi; Alberto Bosi; Alessandro M Vannucchi
B-, T-, and NK-cell lineage involvement in JAK2V617F-positive patients with idiopathic myelofibrosis.
Haematologica 2007;92(2):258-9.
2007: Paola Guglielmelli; Roberta Zini; Costanza Bogani; Simona Salati; Alessandro Pancrazzi; Elisa Bianchi; Francesco Mannelli; Sergio Ferrari; Marie-Caroline Le Bousse-Kerdilès; Alberto Bosi; Giovanni Barosi; Anna Rita Migliaccio; Rossella Manfredini; Alessandro M Vannucchi
Molecular profiling of CD34+ cells in idiopathic myelofibrosis identifies a set of disease-associated genes and reveals the clinical significance of Wilms' tumor gene 1 (WT1).
Stem cells (Dayton, Ohio) 2007;25(1):165-73.
2006: Vanessa Ponziani; Giacomo Gianfaldoni; Francesco Mannelli; Franco Leoni; Stefania Ciolli; Paola Guglielmelli; Elisabetta Antonioli; Giovanni Longo; Alberto Bosi; Alessandro M Vannucchi
The size of duplication does not add to the prognostic significance of FLT3 internal tandem duplication in acute myeloid leukemia patients.
Leukemia 2006;20(11):2074-6.
2006: Cristina Cellai; Anna Laurenzana; Alessandro M Vannucchi; Roberto Caporale; Milena Paglierani; Simonetta Di Lollo; Alessandro Pancrazzi; Francesco Paoletti
Growth inhibition and differentiation of human breast cancer cells by the PAFR antagonist WEB-2086.
British journal of cancer 2006;94(11):1637-42.
2006: Alessandro M Vannucchi; Alessandro Pancrazzi; Costanza Bogani; Elisabetta Antonioli; Paola Guglielmelli
A quantitative assay for JAK2(V617F) mutation in myeloproliferative disorders by ARMS-PCR and capillary electrophoresis.
Leukemia 2006;20(6):1055-60.
2006: Alessandro M Vannucchi; Paola Guglielmelli; Elisabetta Antonioli; Silvia Mappa; Alessandro Pancrazzi; Costanza Bogani; Vanessa Ponziani; Alberto Bosi
Inconsistencies in the association between the JAK2(V617F) mutation and PRV-1 over-expression among the chronic myeloproliferative diseases.
British journal of haematology 2006;132(5):652-4; author reply 654.
2006: Massimo Sanchez; Irving L Weissman; Maria Pallavicini; Mauro Valeri; Paola Guglielmelli; Alessandro M Vannucchi; Giovanni Migliaccio; Anna Rita Migliaccio
Differential amplification of murine bipotent megakaryocytic/erythroid progenitor and precursor cells during recovery from acute and chronic erythroid stress.
Stem cells (Dayton, Ohio) 2006;24(2):337-48.
2006: Carlo Nozzoli; Benedetta Bartolozzi; Stefano Guidi; A Orsi; Alessandro M Vannucchi; Franco Leoni; Alberto Bosi
Epstein-Barr virus-associated post-transplant lymphoproliferative disease with central nervous system involvement after unrelated allogeneic hematopoietic stem cell transplantation.
Leukemia & lymphoma 2006;47(1):167-9.
2005: Fabrizio Martelli; Barbara Ghinassi; Barbara Panetta; Elena Alfani; Valentina Gatta; Alessandro Pancrazzi; Costanza Bogani; Alessandro M Vannucchi; Francesco Paoletti; Giovanni Migliaccio; Anna Rita Migliaccio
Variegation of the phenotype induced by the Gata1low mutation in mice of different genetic backgrounds.
Blood 2005;106(13):4102-13.
2005: Giuseppe Ficarra; F Beninati; Ida Rubino; Alessandro M Vannucchi; G Longo; Pietro Tonelli; Giovan Paolo Pini Prato
Osteonecrosis of the jaws in periodontal patients with a history of bisphosphonates treatment.
Journal of clinical periodontology 2005;32(11):1123-8.
2005: Elisabetta Antonioli; Paola Guglielmelli; Alessandro Pancrazzi; Costanza Bogani; M Verrucci; Vanessa Ponziani; Giovanni Longo; Alberto Bosi; Alessandro M Vannucchi
Clinical implications of the JAK2 V617F mutation in essential thrombocythemia.
Leukemia 2005;19(10):1847-9.
2005: Alessandro M Vannucchi; Alessandro Pancrazzi; Paola Guglielmelli; Simonetta Di Lollo; Costanza Bogani; Gianna Baroni; Lucia Bianchi; Anna Rita Migliaccio; Alberto Bosi; Francesco Paoletti
Abnormalities of GATA-1 in megakaryocytes from patients with idiopathic myelofibrosis.
The American journal of pathology 2005;167(3):849-58.
2005: Giovanni Amabile; Antonella Di Noia; Elena Alfani; Alessandro M Vannucchi; Massimo Sanchez; Domenico Bosco; Anna Rita Migliaccio; Giovanni Migliaccio
Isolation of TPO-dependent subclones from the multipotent 32D cell line.
Blood cells, molecules & diseases 2005;35(2):241-52.
2005: Alessandro M Vannucchi; Anna Rita Migliaccio; Francesco Paoletti; Hédia Chagraoui; Françoise Wendling
Pathogenesis of myelofibrosis with myeloid metaplasia: lessons from mouse models of the disease.
Seminars in oncology 2005;32(4):365-72.
2005: Giacomo Gianfaldoni; Elisabetta Antonioli; Francesco Mannelli; Alessandro M Vannucchi; Alberto Bosi
Chronic relapsing thrombotic thrombocytopenic purpura successfully treated with rituximab: case report.
Journal of chemotherapy (Florence, Italy) 2005;17(4):449-51.
2005: Anna Rita Migliaccio; Rosa Alba Rana; Alessandro M Vannucchi; Francesco Antonio Manzoli
Role of GATA-1 in normal and neoplastic hemopoiesis.
Annals of the New York Academy of Sciences 2005;1044():142-58.
2005: Alessandro M Vannucchi; Lucia Bianchi; Francesco Paoletti; Alessandro Pancrazzi; Eugenio Torre; Mitsuo Nishikawa; Maria Zingariello; Angela Di Baldassarre; Rosa Alba Rana; Rodolfo Lorenzini; Elena Alfani; Giovanni Migliaccio; Anna Rita Migliaccio
A pathobiologic pathway linking thrombopoietin, GATA-1, and TGF-beta1 in the development of myelofibrosis.
Blood 2005;105(9):3493-501.
2005: Alessandro M Vannucchi; Giuseppe Ficarra; Elisabetta Antonioli; Alberto Bosi
Osteonecrosis of the jaw associated with zoledronate therapy in a patient with multiple myeloma.
British journal of haematology 2005;128(6):738.
2005: Anna Laurenzana; Cristina Cellai; Alessandro M Vannucchi; Alessandro Pancrazzi; M N Romanelli; Francesco Paoletti
WEB-2086 and WEB-2170 trigger apoptosis in both ATRA-sensitive and -resistant promyelocytic leukemia cells and greatly enhance ATRA differentiation potential.
Leukemia 2005;19(3):390-5.
2004: Lucia Centurione; Angela Di Baldassarre; Maria Zingariello; Domenico Bosco; Valentina Gatta; Rosa Alba Rana; Vincenzo Langella; Antonio Di Virgilio; Alessandro M Vannucchi; Anna Rita Migliaccio
Increased and pathologic emperipolesis of neutrophils within megakaryocytes associated with marrow fibrosis in GATA-1(low) mice.
Blood 2004;104(12):3573-80.
2004: Alessandro M Vannucchi; Alberto Grossi; Alessandro Pancrazzi; Elisabetta Antonioli; Paola Guglielmelli; Francesca Balestri; Monica Biscardi; Simona Bulgarelli; Giovanni Longo; Claudio Graziano; Luigi Gugliotta; Alberto Bosi
PRV-1, erythroid colonies and platelet Mpl are unrelated to thrombosis in essential thrombocythaemia.
British journal of haematology 2004;127(2):214-9.
2004: Alessandro M Vannucchi; Lucia Bianchi; Francesco Paoletti; Viviana Di Giacomo; Giovanni Migliaccio; Anna Rita Migliaccio
Impaired GATA-1 expression and myelofibrosis in an animal model.
Pathologie-biologie 2004;52(5):275-9.
2004: Stefania Ciolli; Alessandro M Vannucchi; Franco Leoni; Carlo Nozzoli; Giovanni Longo; A Salati; Alessandro Pancrazzi; Lucia Bianchi; F Gigli; Alberto Bosi
Internal tandem duplications of Flt3 gene (Flt3/ITD) predicts a poor post-remission outcome in adult patients with acute non-promyelocytic leukemia.
Leukemia & lymphoma 2004;45(1):73-8.
2003: Anna Rita Migliaccio; Rodolfo Lorenzini; Alessandro M Vannucchi; Gerald J Spangrude; Giovanni Migliaccio
Robust levels of long-term multilineage reconstitution in the absence of stem cell self-replication in W/Wv mice transplanted with purified stem cells.
Journal of hematotherapy & stem cell research 2003;12(4):409-24.
2003: Anna Rita Migliaccio; Rosa Alba Rana; Massimo Sanchez; Rodolfo Lorenzini; Lucia Centurione; Lucia Bianchi; Alessandro M Vannucchi; Giovanni Migliaccio; Stuart H Orkin
GATA-1 as a regulator of mast cell differentiation revealed by the phenotype of the GATA-1low mouse mutant.
The Journal of experimental medicine 2003;197(3):281-96.
2002: Alessandro M Vannucchi; Lucia Bianchi; Cristina Cellai; Francesco Paoletti; Rosa Alba Rana; Rodolfo Lorenzini; Giovanni Migliaccio; Anna Rita Migliaccio
Development of myelofibrosis in mice genetically impaired for GATA-1 expression (GATA-1(low) mice).
Blood 2002;100(4):1123-32.
2002: Cristina Cellai; Anna Laurenzana; Alessandro M Vannucchi; Nunzia Della Malva; Lucia Bianchi; Francesco Paoletti
Specific PAF antagonist WEB-2086 induces terminal differentiation of murine and human leukemia cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(7):733-5.
2002: Alberto Bosi; Benedetta Bartolozzi; Alessandro M Vannucchi; Alessandra Orsi; Stefano Guidi; Pierluigi Rossi Ferrini
Polymerase chain reaction-based "pre-emptive" therapy with cidofovir for cytomegalovirus reactivation in allogeneic hematopoietic stem cells transplantation recipients: a prospective study.
Haematologica 2002;87(4):446-7.
2001: Alessandro M Vannucchi; Lucia Bianchi; Cristina Cellai; Francesco Paoletti; Valentina Carrai; A Calzolari; Lucia Centurione; Rodolfo Lorenzini; Claudio Carta; Elena Alfani; Massimo Sanchez; Giovanni Migliaccio; Anna Rita Migliaccio
Accentuated response to phenylhydrazine and erythropoietin in mice genetically impaired for their GATA-1 expression (GATA-1(low) mice).
Blood 2001;97(10):3040-50.
2001: Alessandro M Vannucchi; S Glinz; Alberto Bosi; Roberto Caporale; Pierluigi Rossi Ferrini
Selective ex vivo expansion of cytomegalovirus-specific CD4+ and CD8+ T lymphocytes using dendritic cells pulsed with a human leucocyte antigen A*0201-restricted peptide.
British journal of haematology 2001;113(2):479-82.
2000: Alessandro M Vannucchi; Francesco Paoletti; Silvia Linari; Cristina Cellai; Roberto Caporale; Pierluigi Rossi Ferrini; Massimo Sanchez; Giovanni Migliaccio; Anna Rita Migliaccio
Identification and characterization of a bipotent (erythroid and megakaryocytic) cell precursor from the spleen of phenylhydrazine-treated mice.
Blood 2000;95(8):2559-68.
1999: Alessandro M Vannucchi; Silvia Linari; C S Lin; Mark J Koury; Maurice C Bondurant; Anna Rita Migliaccio
Increased expression of the distal, but not of the proximal, Gata1 transcripts during differentiation of primary erythroid cells.
Journal of cellular physiology 1999;180(3):390-401.
1999: Alberto Bosi; D Laszlo; Stefano Bacci; Rosa Fanci; Stefano Guidi; Riccardo Saccardi; Alessandro M Vannucchi; Pierluigi Rossi Ferrini
An open evaluation of triple antibiotic therapy including vancomycin for febrile bone marrow transplant recipients with severe neutropenia.
Journal of chemotherapy (Florence, Italy) 1999;11(4):287-92.
1999: Alessandro M Vannucchi; S Glinz; Alberto Bosi; C Fallai; Pierluigi Rossi Ferrini
Detection of contaminating tumor cells by RT-PCR in breast cancer patients.
Bone marrow transplantation 1999;24(2):228-9.
1999: Cristina Cellai; R Matucci; Alessandro M Vannucchi; Francesco Paoletti
Constitutive muscarinic receptors are involved in the growth and differentiation of friend erythroleukemia cells.
Journal of cellular physiology 1999;178(3):333-40.
1998: Alessandro M Vannucchi; Alberto Bosi; S Glinz; Paolo Pacini; Silvia Linari; Riccardo Saccardi; Renato Alterini; Luigi Rigacci; Stefano Guidi; L Lombardini; Giovanni Longo; M P Mariani; Pierluigi Rossi Ferrini
Evaluation of breast tumour cell contamination in the bone marrow and leukapheresis collections by RT-PCR for cytokeratin-19 mRNA.
British journal of haematology 1998;103(3):610-7.
1998: Silvia Linari; Alessandro M Vannucchi; Stefania Ciolli; Franco Leoni; Roberto Caporale; Alberto Grossi; Gabriella Pagliai; Valeria Santini; Francesco Paoletti; Pierluigi Rossi Ferrini
Coexpression of erythroid and megakaryocytic genes in acute erythroblastic (FAB M6) and megakaryoblastic (FAB M7) leukaemias.
British journal of haematology 1998;102(5):1335-7.
1998: Alberto Bosi; Maurizio Zazzi; Aldo Amantini; Martino Cellerini; Alessandro M Vannucchi; Angelo De Milito; Stefano Guidi; Riccardo Saccardi; L Lombardini; D Laszlo; Pierluigi Rossi Ferrini
Fatal herpesvirus 6 encephalitis after unrelated bone marrow transplant.
Bone marrow transplantation 1998;22(3):285-8.
1998: Alberto Grossi; Alessandro M Vannucchi; P Bacci; Roberto Caporale; G Cappelli; G Visconti; Gabriella Pagliai; Pierluigi Rossi Ferrini
Erythropoietin upregulates the expression of its own receptor in TF-1 cell line.
Leukemia research 1998;22(2):145-51.
1997: Alessandro M Vannucchi; Silvia Linari; Cristina Cellai; Mark J Koury; Francesco Paoletti
Constitutive and inducible expression of megakaryocyte-specific genes in Friend erythroleukaemia cells.
British journal of haematology 1997;99(3):500-8.
1997: Laura Bonsi; Alberto Grossi; Pierluigi Strippoli; Fabio Tumietto; Roberto Tonelli; Alessandro M Vannucchi; Antonella Ronchi; Sergio Ottolenghi; G Visconti; Gian Carlo Avanzi; Luigi Pegoraro; Gian Paolo Bagnara
An erythroid and megakaryocytic common precursor cell line (B1647) expressing both c-mpl and erythropoietin receptor (Epo-R) proliferates and modifies globin chain synthesis in response to megakaryocyte growth and development factor (MGDF) but not to erythropoietin (Epo).
British journal of haematology 1997;98(3):549-59.
1997: E Ashihara; Alessandro M Vannucchi; Giovanni Migliaccio; A R Migliaccio
Growth factor receptor expression during in vitro differentiation of partially purified populations containing murine stem cells.
Journal of cellular physiology 1997;171(3):343-56.
1997: Giovanni Longo; E Filimberti; S Cinotti; Alessandro M Vannucchi; L Lombardini; Pierluigi Rossi Ferrini
Pretransplant factor XII levels correlate with prognosis in patients undergoing autologous graft for hematological malignancies.
Haematologica 1997;82(3):360-1.
1997: D Laszlo; Stefano Bacci; Alberto Bosi; Rosa Fanci; Stefano Guidi; Riccardo Saccardi; Alessandro M Vannucchi; Pierluigi Rossi Ferrini
Randomized trial comparing netilmicin plus imipenem-cilastatin versus netilmicin plus ceftazidime as empiric therapy for febrile neutropenic bone marrow transplant recipients.
Journal of chemotherapy (Florence, Italy) 1997;9(2):95-101.
1997: Alessandro M Vannucchi; Alberto Bosi; Silvia Linari; Stefano Guidi; Giovanni Longo; L Lombardini; M P Mariani; Riccardo Saccardi; D Laszlo; Pierluigi Rossi Ferrini
High doses of recombinant human erythropoietin fail to accelerate platelet reconstitution in allogeneic bone marrow transplantation. Results of a pilot study.
Haematologica 1997;82(1):53-6.
1996: Francesco Paoletti; Alessandra Mocali; Cristina Cellai; Roberto Caporale; Alessandro M Vannucchi
Megakaryocyte-like increase in ploidy of Friend's erythroleukemia cells induced to endoreplication by colcemid.
Experimental hematology 1996;24(12):1441-8.
1996: Valeria Santini; A Zoccolante; Alberto Bosi; Stefano Guidi; Riccardo Saccardi; Alessandro M Vannucchi; G Martinazzo; Pietro Antonio Bernabei; Pierluigi Rossi Ferrini
Detection of bcr/abl transcripts by RT-PCR and their colorimetric evaluation in chronic myeloid leukemia patients receiving allogeneic bone marrow transplantation.
Haematologica 1996;81(3):201-7.
1996: Alessandro M Vannucchi; Alberto Bosi; A Ieri; Stefano Guidi; Riccardo Saccardi; L Lombardini; Silvia Linari; D Laszlo; Giovanni Longo; Pierluigi Rossi Ferrini
Combination therapy with G-CSF and erythropoietin after autologous bone marrow transplantation for lymphoid malignancies: a randomized trial.
Bone marrow transplantation 1996;17(4):527-31.
1995: Alessandro M Vannucchi; Alberto Bosi; L Lombardini; Alberto Grossi; P Bacci; Stefano Guidi; Riccardo Saccardi; Pierluigi Rossi Ferrini
Circulating CFU-E during hematopoietic recovery after allogeneic bone marrow transplantation: relationship to erythroid engraftment.
Experimental hematology 1995;23(13):1337-40.
1995: Francesco Paoletti; Alessandro M Vannucchi; Alessandra Mocali; Roberto Caporale; S A Burstein
Identification and conditions for selective expression of megakaryocytic markers in Friend erythroleukemia cells.
Blood 1995;86(7):2624-31.
1995: D Laszlo; Alberto Bosi; Stefano Guidi; Riccardo Saccardi; Alessandro M Vannucchi; L Lombardini; Giovanni Longo; Rosa Fanci; Alberta Azzi; R De Santis
Prostaglandin E2 bladder instillation for the treatment of hemorrhagic cystitis after allogeneic bone marrow transplantation.
Haematologica 1995;80(5):421-5.
1995: Alessandro M Vannucchi; Alberto Bosi; D Laszlo; Stefano Guidi; Riccardo Saccardi; Pierluigi Rossi Ferrini
Treatment of a delayed graft failure after allogeneic bone marrow transplantation with IL-3 and GM-CSF.
Haematologica 1995;80(4):341-3.
1995: Alberto Grossi; Alessandro M Vannucchi; P Bacci; Giovanni Longo; D Rafanelli; Renato Alterini; Pierluigi Rossi Ferrini
In vivo administration of stem cell factor enhances both proliferation and maturation of murine megakaryocytes.
Haematologica 1995;80(1):18-24.
1994: Alessandro M Vannucchi; D Rafanelli; Giovanni Longo; Alberto Bosi; Stefano Guidi; Riccardo Saccardi; E Filimberti; S Cinotti; Alberto Grossi; Massimo Morfini
Early hemostatic alterations following bone marrow transplantation: a prospective study.
Haematologica 1994;79(6):519-25.
1994: Alberta Azzi; Rosa Fanci; Alberto Bosi; S Ciappi; Krystyna Zakrzewska; R De Santis; D Laszlo; Stefano Guidi; Riccardo Saccardi; Alessandro M Vannucchi
Monitoring of polyomavirus BK viruria in bone marrow transplantation patients by DNA hybridization assay and by polymerase chain reaction: an approach to assess the relationship between BK viruria and hemorrhagic cystitis.
Bone marrow transplantation 1994;14(2):235-40.
1994: Alessandro M Vannucchi; Alberto Grossi; D Rafanelli; M Statello; S Cinotti; Pierluigi Rossi Ferrini
Inhibition of erythropoietin production in vitro by human interferon gamma.
British journal of haematology 1994;87(1):18-23.
1994: Alessandro M Vannucchi; A Bost; A Grossi; Stefano Guidi; Riccardo Saccardi; Pierluigi Rossi Ferrini
Down-modulation of serum erythropoietin levels following cyclosporin A infusion.
Bone marrow transplantation 1994;13(4):497-8.
1993: Alessandro M Vannucchi; Alberto Bosi; Alberto Grossi; Stefano Guidi; Riccardo Saccardi; P Bacci; L Lombardini; Pierluigi Rossi Ferrini
The use of erythropoietin in the treatment of post-bone marrow transplantation anemia.
The International journal of artificial organs 1993;16 Suppl 5():8-12.
1993: Alessandro M Vannucchi; A Grossi; Alberto Bosi; D Rafanelli; M Statello; Stefano Guidi; Riccardo Saccardi; Pierluigi Rossi Ferrini
Effects of cyclosporin A on erythropoietin production by the human Hep3B hepatoma cell line.
Blood 1993;82(3):978-84.
1993: Alberto Bosi; Stefano Guidi; A Messori; Riccardo Saccardi; L Lombardini; Alessandro M Vannucchi; Rosa Fanci; Pierluigi Rossi Ferrini
Ondansetron versus chlorpromazine for preventing emesis in bone marrow transplant recipients: a double-blind randomized study.
Journal of chemotherapy (Florence, Italy) 1993;5(3):191-6.
1993: Pierluigi Rossi Ferrini; Valeria Santini; Stefania Ciolli; Alberto Grossi; Franco Leoni; D Rafanelli; Alessandro M Vannucchi
The role of haematopoietic growth factors in the treatment of myelodysplastic syndromes.
Hematological oncology 1993;11 Suppl 1():32-5.
1992: Alessandro M Vannucchi; Alberto Grossi; Francesco Paoletti; D Rafanelli; P Bacci; Pierluigi Rossi Ferrini
Constitutive expression of a megakaryocytic functional property by murine erythroleukemia (Friend) cells: the incorporation of serotonin.
Experimental hematology 1992;20(11):1296-301.
1992: P Bacci; Alberto Grossi; Alessandro M Vannucchi; D Rafanelli; A Casini; M De Luca
Effects of miocamycin and erythromycin on polymorphonuclear cell function.
Journal of chemotherapy (Florence, Italy) 1992;4(5):268-70.
1992: Francesco Paoletti; Alessandra Mocali; Alessandro M Vannucchi
Acetylcholinesterase in murine erythroleukemia (Friend) cells: evidence for megakaryocyte-like expression and potential growth-regulatory role of enzyme activity.
Blood 1992;79(11):2873-9.
1992: D Rafanelli; Alberto Grossi; Giovanni Longo; Alessandro M Vannucchi; P Bacci; Pierluigi Rossi Ferrini
Recombinant human erythropoietin for treatment of myelodysplastic syndromes.
Leukemia 1992;6(4):323-7.
1992: Alessandro M Vannucchi; Alberto Bosi; Alberto Grossi; Stefano Guidi; Riccardo Saccardi; L Lombardini; Pierluigi Rossi Ferrini
Stimulation of erythroid engraftment by recombinant human erythropoietin in ABO-compatible, HLA-identical, allogeneic bone marrow transplant patients.
Leukemia 1992;6(3):215-9.
1992: Alberto Bosi; Rosa Fanci; Patrizia Pecile; Stefano Guidi; Riccardo Saccardi; Alessandro M Vannucchi; Giovanni Longo; E Donnini; Alessandra Orsi; Pierluigi Rossi Ferrini
Aztreonam versus colistin-neomycin for selective decontamination of the digestive tract in patients undergoing bone marrow transplantation: a randomized study.
Journal of chemotherapy (Florence, Italy) 1992;4(1):30-4.
1991: Alessandro M Vannucchi; Alberto Grossi; Alberto Bosi; D Rafanelli; Stefano Guidi; Riccardo Saccardi; Renato Alterini; Pierluigi Rossi Ferrini
Impaired erythropoietin production in mice treated with cyclosporin A.
Blood 1991;78(6):1615-8.
1991: Alessandro M Vannucchi; Giovanni Longo; Alberto Bosi; S Cinotti; E Filimberti; Stefano Guidi; Riccardo Saccardi; Massimo Morfini; E Boni; Pierluigi Rossi Ferrini
Early haemostatic modifications following cryopreserved graft infusion.
Bone marrow transplantation 1991;8(3):171-6.
1991: Alberto Bosi; Alessandro M Vannucchi; A Grossi; Stefano Guidi; Riccardo Saccardi; D Rafanelli; G Longo; Pierluigi Rossi Ferrini
Inadequate erythropoietin production in allogeneic bone marrow transplant patients.
Haematologica 1991;76(4):280-4.
1991: Alberto Bosi; Alessandro M Vannucchi; Alberto Grossi; Stefano Guidi; L Vannucchi; Riccardo Saccardi; Pietro Antonio Bernabei; G Longo; D Rafanelli; Pierluigi Rossi Ferrini
Serum erythropoietin levels in patients undergoing autologous bone marrow transplantation.
Bone marrow transplantation 1991;7(6):421-5.
1991: A Grossi; Alessandro M Vannucchi; G Longo; D Rafanelli; P Rossi Ferrini
[Essential thrombocythemia: conventional therapy].
Haematologica 1991;76 Suppl 3():368-70.
1991: J H Amuasi; P Ferri; Alberto Grossi; L Vannucchi; Alessandro M Vannucchi; Pierluigi Rossi Ferrini
Quantitative platelet imaging and comparison of four mathematical models for the evaluation of platelet mean life span in patients with chronic immune thrombocytopenia.
Haematologica 1991;76(2):104-8.
1991: Alberto Bosi; Alessandro M Vannucchi; A Grossi; Stefano Guidi; D Rafanelli; Riccardo Saccardi; Pierluigi Rossi Ferrini
Serum erythropoietin levels in allogeneic, non T-depleted bone marrow transplantation, and the effects of rhEpo administration.
Bone marrow transplantation 1991;7 Suppl 2():87.
1990: Alessandro M Vannucchi; Alberto Grossi; D Rafanelli; Pierluigi Rossi Ferrini
In vivo stimulation of megakaryocytopoiesis by recombinant murine granulocyte-macrophage colony-stimulating factor.
Blood 1990;76(8):1473-80.
1990: D Rafanelli; Alberto Grossi; Alessandro M Vannucchi; S Cinotti; Massimo Morfini; Pierluigi Rossi Ferrini
The effect of picotamide on platelet function in patients with myeloproliferative disorders.
Thrombosis and haemostasis 1990;63(3):525-6.
1990: Alberto Bosi; E De Majo; Stefano Guidi; F Parri; Riccardo Saccardi; Alessandro M Vannucchi; Rosa Fanci; Pierluigi Rossi Ferrini
Kinetics of anti-CMV antibodies after administration of intravenous immunoglobulins to bone marrow transplant recipients.
Haematologica 1990;75(2):109-12.
1990: Alberto Grossi; Alessandro M Vannucchi; Pierluigi Rossi Ferrini
Humoral regulation of megakaryocytopoiesis.
Biotherapy (Dordrecht, Netherlands) 1990;2(4):375-83.
1990: Alessandro M Vannucchi; Alberto Grossi; D Rafanelli; L Vannucchi; Pierluigi Rossi Ferrini
Binding of recombinant human 125I-erythropoietin to CFU-E from the spleen of anemic mice.
Haematologica 1990;75(1):21-6.
1989: Alessandro M Vannucchi; Alberto Grossi; D Rafanelli; L Vannucchi; Pierluigi Rossi Ferrini
A dot assay for the erythropoietin receptor using human recombinant 125I-erythropoietin.
Analytical biochemistry 1989;182(1):182-6.
1989: Pierluigi Rossi Ferrini; A Grossi; Valeria Santini; Alessandro M Vannucchi
[GM-CSF: its clinical administration; the treatment of aplasia].
Haematologica 1989;74(5 Suppl):489-500.
1989: Alberto Grossi; Alessandro M Vannucchi; D Rafanelli; Pierluigi Rossi Ferrini
Recombinant human erythropoietin has little influence on megakaryocytopoiesis in mice.
British journal of haematology 1989;71(4):463-8.
1988: Alessandro M Vannucchi; Alberto Grossi; D Rafanelli; L Vannucchi; Pierluigi Rossi Ferrini
Serotonin incorporation as a marker of murine megakaryocyte proliferation in liquid cultures.
Experimental hematology 1988;16(11):916-21.
1988: Alessandro M Vannucchi; Alberto Grossi; D Rafanelli; Pierluigi Rossi Ferrini; G Ramponi
Partial purification and biochemical characterization of human plasma thrombopoietin.
Leukemia 1988;2(4):236-40.
1988: Alberto Grossi; S Rosseti; Alessandro M Vannucchi; D Rafanelli; Pierluigi Rossi Ferrini
Occurrence of haemorrhagic and thrombotic events in myeloproliferative disorders: a retrospective study of 108 patients.
Clinical and laboratory haematology 1988;10(2):167-75.
1987: Alberto Grossi; Alessandro M Vannucchi; D Rafanelli; L Vannucchi; Pierluigi Rossi Ferrini
Megakaryocyte progenitors in the bone marrow and peripheral blood of patients with myeloproliferative diseases.
American journal of hematology 1987;25(4):371-6.
1987: A Grossi; Alessandro M Vannucchi; D Rafanelli; Pierluigi Rossi Ferrini
Biological characterization of partially purified human urinary thrombopoietin.
Haematologica 1987;72(4):291-5.
1986: Alberto Grossi; Alessandro M Vannucchi; D Rafanelli; E Filimberti; Pierluigi Rossi Ferrini
Beta-thromboglobulin content in megakaryocytes of patients with myeloproliferative diseases.
Thrombosis research 1986;43(3):367-74.
1986: A Grossi; Alessandro M Vannucchi; P Casprini; Massimo Morfini; P R Ferrini
Effects of high-dose intravenous gammaglobulin on kinetic parameters of 51Cr-labelled platelets in chronic ITP.
Haematologica 1986;71(2):123-7.
1986: Alessandro M Vannucchi; A Grossi; D Rafanelli; S DiLollo; C Bertani; P RossiFerrini
Partial purification of a thrombopoietic stimulating activity from human urine.
Progress in clinical and biological research 1986;215():221-5.
1985: Massimo Morfini; Alessandro M Vannucchi; Alberto Grossi; S Cinotti; D Rafanelli; Pierluigi Rossi Ferrini
Direct evidence that high dose intravenous gammaglobulin blocks splenic and hepatic sequestration of 51Cr-labeled platelets in ITP.
Thrombosis and haemostasis 1985;54(2):554.
1985: A Grossi; Alessandro M Vannucchi; D Rafanelli; Pierluigi Rossi Ferrini
Megakaryocyte enrichment procedures.
Blood 1985;65(2):506-7.
1984: A Grossi; Alessandro M Vannucchi; D Rafanelli; P Rossi Ferrini
Transient remission of chronic idiopathic thrombocytopenic purpura during septic abscess and pneumothorax.
Haematologica 1984;69(5):572-5.
1984: Giovanni Longo; franco cecchi; A Grossi; M Matucci; D Rafanelli; Alessandro M Vannucchi; P Casprini; S Vannini; Massimo Morfini; Alberto Dolara
Coagulation and platelet function in hypertrophic cardiomyopathy.
Thrombosis and haemostasis 1984;51(2):299.
1983: A Grossi; Alessandro M Vannucchi; P Casprini; Stefano Guidi; D Rafanelli; M G Pecchioli; Pierluigi Rossi Ferrini
Different patterns of platelet turnover in chronic idiopathic thrombocytopenic purpura.
Scandinavian journal of haematology 1983;31(3):206-14.