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Philippe Vanparys

Research Profile

Procedures

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Mouse

Chemicals & Drugs

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Cell Transformation, Neoplastic

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Publications

TOP 3
Sandra Verstraelen; Bart De Wever; An Jacobs; Philippe Vanparys
Improvement of the Bovine Corneal Opacity and Permeability (BCOP) assay as an in vitro alternative to the Draize rabbit eye irritation test.
Raffaella Corvi; Philippe Vanparys
International prevalidation study on cell transformation assay. Preface.
Philippe Vanparys; Marilyn Aardema; Raffaella Corvi; Laura Gribaldo; Makoto Hayashi; Sebastian Hoffmann; Leonard M Schechtman
Application of in vitro cell transformation assays in regulatory toxicology for pharmaceuticals, chemicals, food products and cosmetics.

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All Publications

2013: Sandra Verstraelen; Bart De Wever; An Jacobs; Philippe Vanparys
Improvement of the Bovine Corneal Opacity and Permeability (BCOP) assay as an in vitro alternative to the Draize rabbit eye irritation test.
Toxicology in vitro : an international journal published in association with BIBRA 2013;27(4):1298-311.
2012: Raffaella Corvi; Philippe Vanparys
International prevalidation study on cell transformation assay. Preface.
Mutation research 2012;744(1):1-2.
2012: Philippe Vanparys; Marilyn Aardema; Raffaella Corvi; Laura Gribaldo; Makoto Hayashi; Sebastian Hoffmann; Leonard M Schechtman
Application of in vitro cell transformation assays in regulatory toxicology for pharmaceuticals, chemicals, food products and cosmetics.
Mutation research 2012;744(1):111-6.
2012: Raffaella Corvi; Laura Gribaldo; Makoto Hayashi; Sebastian Hoffmann; Leonard M Schechtman; Marilyn Aardema; Philippe Vanparys
ECVAM prevalidation study on in vitro cell transformation assays: general outline and conclusions of the study.
Mutation research 2012;744(1):12-9.
2011: David Kirkland; Lesley Reeve; David Gatehouse; Philippe Vanparys
A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins.
Mutation research 2011;721(1):27-73.
2011: Tom Henkens; Sarah Snykers; Mathieu Vinken; Joanna Fraczek; Aneta Lukaszuk; Dirk Tourwé; Geert Verheyen; Jacky Van Gompel; Philippe Vanparys; Vera Rogiers; Tamara Vanhaecke
Preservation of hepatocellular functionality in cultures of primary rat hepatocytes upon exposure to 4-Me2N-BAVAH, a hydroxamate-based HDAC-inhibitor.
Toxicology in vitro : an international journal published in association with BIBRA 2011;25(1):100-9.
2011: Philippe Vanparys; Raffaella Corvi; Marilyn Aardema; Laura Gribaldo; Makoto Hayashi; Sebastian Hoffmann; Leonard Schechtman
ECVAM prevalidation of three cell transformation assays.
ALTEX 2011;28(1):56-9.
2010: Freddy Van Goethem; Erik Hansen; Marc Sysmans; Ann De Smedt; Philippe Vanparys; Jacky Van Gompel
Development of a new opacitometer for the bovine corneal opacity and permeability (BCOP) assay.
Toxicology in vitro : an international journal published in association with BIBRA 2010;24(6):1854-61.
2009: Stefan Pfuhler; David Kirkland; Peter Kasper; Makoto Hayashi; Philippe Vanparys; Paul Carmichael; Stephen D Dertinger; David Eastmond; Azeddine Elhajouji; Cyrille Krul; Andreas Rothfuss; Gabriele Schoening; Andrew Smith; Guenter Speit; Claire Thomas; Jan van Benthem; Raffaella Corvi
Reduction of use of animals in regulatory genotoxicity testing: Identification and implementation opportunities-Report from an ECVAM workshop.
Mutation research 2009;680(1-2):31-42.
2009: Philip Marx-Stoelting; Els Adriaens; Hans-Jürgen Ahr; Susanne Bremer; Bernward Garthoff; Heinz-Peter Gelbke; Aldert Piersma; Cristian Pellizzer; Ulrike Reuter; Vera Rogiers; Barbara Schenk; Silke Schwengberg; Andrea Seiler; Horst Spielmann; Margino Steemans; Donald B Stedman; Philippe Vanparys; Joan-Albert Vericat; Miriam Verwei; Femke van der Water; Marc Weimer; Michael Schwarz
A review of the implementation of the embryonic stem cell test (EST). The report and recommendations of an ECVAM/ReProTect Workshop.
Alternatives to laboratory animals : ATLA 2009;37(3):313-28.
2008: Annelieke K Peters; Gert Van de Wouwer; Barbara Weyn; Geert R Verheyen; Philippe Vanparys; Jacques Van Gompel
Automated analysis of contractility in the embryonic stem cell test, a novel approach to assess embryotoxicity.
Toxicology in vitro : an international journal published in association with BIBRA 2008;22(8):1948-56.
2008: Ann De Smedt; Margino Steemans; Marlies De Boeck; Annelieke K Peters; Bas-jan van der Leede; Freddy Van Goethem; Ann Lampo; Philippe Vanparys
Optimisation of the cell cultivation methods in the embryonic stem cell test results in an increased differentiation potential of the cells into strong beating myocard cells.
Toxicology in vitro : an international journal published in association with BIBRA 2008;22(7):1789-96.
2008: Annelieke K Peters; Margino Steemans; Erik Hansen; Natalie Mesens; Geert R Verheyen; Philippe Vanparys
Evaluation of the embryotoxic potency of compounds in a newly revised high throughput embryonic stem cell test.
Toxicological sciences : an official journal of the Society of Toxicology 2008;105(2):342-50.
2006: Freddy Van Goethem; Els Adriaens; N Alépée; F Straube; B De Wever; M Cappadoro; S Catoire; E Hansen; A Wolf; Philippe Vanparys
Prevalidation of a new in vitro reconstituted human cornea model to assess the eye irritating potential of chemicals.
Toxicology in vitro : an international journal published in association with BIBRA 2006;20(1):1-17.
2005: Marlies De Boeck; Bas-jan van der Leede; Freddy Van Goethem; Ann De Smedt; Margino Steemans; Ann Lampo; Philippe Vanparys
Flow cytometric analysis of micronucleated reticulocytes: Time- and dose-dependent response of known mutagens in mice, using multiple blood sampling.
Environmental and molecular mutagenesis 2005;46(1):30-42.
2005: Dorothea K Torous; Nikki E Hall; Anne H Illi-Love; Marilyn S Diehl; Karin Cederbrant; Kerstin Sandelin; Ingrid Pontén; George Bolcsfoldi; Lynnette Ferguson; Amira Pearson; Jenness B Majeska; James P Tarca; Geoffrey M Hynes; Anthony Lynch; James P McNamee; Pascale V Bellier; Monique Parenteau; David Blakey; Janet Bayley; Bas-Jan M van der Leede; Philippe Vanparys; Philip R Harbach; Shuou Zhao; Anthony L Filipunas; Carol W Johnson; Carol R Tometsko; Stephen D Dertinger
Interlaboratory validation of a CD71-based flow cytometric method (Microflow) for the scoring of micronucleated reticulocytes in mouse peripheral blood.
Environmental and molecular mutagenesis 2005;45(1):44-55.
2001: Els Adriaens; K Dierckens; Tiene G M Bauters; Hans J Nelis; Freddy Van Goethem; Philippe Vanparys; Jean Paul Remon
The mucosal toxicity of different benzalkonium chloride analogues evaluated with an alternative test using slugs.
Pharmaceutical research 2001;18(7):937-42.