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James Varani

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Durga Attili; Michael Dame; Brian Jenkins; Muhammad Nadeem Aslam; James Varani
Growth control in colon epithelial cells: gadolinium enhances calcium-mediated growth regulation.
Bruce L Riser; Yiru Xu; Durga Attili; Narasimharao Bhagavathula; Gary J Fisher; Kendra Garchow; Feridoon Najmabadi; Patricia Perone; James Varani
Gadolinium-induced fibrosis is counter-regulated by CCN3 in human dermal fibroblasts: a model for potential treatment of nephrogenic systemic fibrosis.
Muhammad Nadeem Aslam; Ingrid L Bergin; Anna Hampton; Steven Kunkel; Madhav Naik; Howard G Rush; Ron Allen; James Varani
A multi-mineral natural product inhibits liver tumor formation in C57BL/6 mice.

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All Publications

2012: Durga Attili; Michael Dame; Brian Jenkins; Muhammad Nadeem Aslam; James Varani
Growth control in colon epithelial cells: gadolinium enhances calcium-mediated growth regulation.
Biological trace element research 2012;150(1-3):467-76.
2012: Bruce L Riser; Yiru Xu; Durga Attili; Narasimharao Bhagavathula; Gary J Fisher; Kendra Garchow; Feridoon Najmabadi; Patricia Perone; James Varani
Gadolinium-induced fibrosis is counter-regulated by CCN3 in human dermal fibroblasts: a model for potential treatment of nephrogenic systemic fibrosis.
Journal of cell communication and signaling 2012;6(2):97-105.
2012: Muhammad Nadeem Aslam; Ingrid L Bergin; Anna Hampton; Steven Kunkel; Madhav Naik; Howard G Rush; Ron Allen; James Varani
A multi-mineral natural product inhibits liver tumor formation in C57BL/6 mice.
Biological trace element research 2012;147(1-3):267-74.
2012: Katherine Bleavins; Michael Dame; Sasha Meshinchi; Madhav Naik; Patricia Perone; Muneeb Rehman; Muhammad Nadeem Aslam; Narasimharao Bhagavathula; James Varani
Stimulation of fibroblast proliferation by insoluble gadolinium salts.
Biological trace element research 2012;145(2):257-67.
2012: Anna L Hampton; Gerald A Hish; Madhav Naik; Tejaswi Paruchuri; Kathleen A Patterson; Edward D Rothman; Muhammad Nadeem Aslam; Ingrid L Bergin; James Varani; Howard G Rush
Progression of ulcerative dermatitis lesions in C57BL/6Crl mice and the development of a scoring system for dermatitis lesions.
Journal of the American Association for Laboratory Animal Science : JAALAS 2012;51(5):586-93.
2012: Muhammad Nadeem Aslam; Ingrid L Bergin; Michael Dame; Anna Hampton; Madhav Naik; Tejaswi Paruchuri; Muneeb Rehman; Howard G Rush; James Varani
A multimineral natural product from red marine algae reduces colon polyp formation in C57BL/6 mice.
Nutrition and cancer 2012;64(7):1020-8.
2011: William Jenkins; Narasimharao Bhagavathula; Michael K Dame; Muhammad Nadeem Aslam; Patricia Perone; Kyle Walker; Marissa DaSilva; James Varani
Fibroblast response to lanthanoid metal ion stimulation: potential contribution to fibrotic tissue injury.
Biological trace element research 2011;144(1-3):621-35.
2011: Wei Zeng; Abd Tahrani; Sharon Hughes; Jayadave Shakher; Kiran Dubb; James Varani; Martin J Stevens
Effects of a synthetic retinoid on skin structure, matrix metalloproteinases, and procollagen in healthy and high-risk subjects with diabetes.
Journal of diabetes and its complications 2011;25(6):398-404.
2011: James Varani
Calcium, calcium-sensing receptor and growth control in the colonic mucosa.
Histology and histopathology 2011;26(6):769-79.
2011: Michael Dame; Indiradevi Veerapaneni; Narasimharao Bhagavathula; Madhav Naik; James Varani
Human colon tissue in organ culture: calcium and multi-mineral-induced mucosal differentiation.
In vitro cellular & developmental biology. Animal 2011;47(1):32-8.
2010: Narasimharao Bhagavathula; Michael K Dame; Marissa DaSilva; William Jenkins; Patricia Perone; Muhammad N Aslam; James Varani
Fibroblast response to gadolinium: role for platelet-derived growth factor receptor.
Investigative radiology 2010;45(12):769-77.
2010: Marissa DaSilva; Monica O'Brien Deming; Suzanne E G Fligiel; Michael Dame; Kent J Johnson; Richard D Swartz; James Varani
Responses of human skin in organ culture and human skin fibroblasts to a gadolinium-based MRI contrast agent: comparison of skin from patients with end-stage renal disease and skin from healthy subjects.
Investigative radiology 2010;45(11):733-9.
2010: Muhammad Nadeem Aslam; Roscoe L Warner; Narasimharao Bhagavathula; Isaac Ginsburg; James Varani
A multi-component herbal preparation (PADMA 28) improves structure/function of corticosteroid-treated skin, leading to improved wound healing of subsequently induced abrasion wounds in rats.
Archives of dermatological research 2010;302(9):669-77.
2010: Hal Blumberg; Huyen Dinh; Charles Dean; Esther S Trueblood; Keith Bailey; Donna Shows; Narasimharao Bhagavathula; Muhammad Nadeem Aslam; James Varani; Jennifer E Towne; John E Sims
IL-1RL2 and its ligands contribute to the cytokine network in psoriasis.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(7):4354-62.
2010: Muhammad Nadeem Aslam; Jaclynn M Kreider; Tejaswi Paruchuri; Narasimharao Bhagavathula; Marissa DaSilva; Ronald F Zernicke; Steven A Goldstein; James Varani
A mineral-rich extract from the red marine algae Lithothamnion calcareum preserves bone structure and function in female mice on a Western-style diet.
Calcified tissue international 2010;86(4):313-24.
2010: Muhammad Nadeem Aslam; Tejaswi Paruchuri; Narasimharao Bhagavathula; James Varani
A mineral-rich red algae extract inhibits polyp formation and inflammation in the gastrointestinal tract of mice on a high-fat diet.
Integrative cancer therapies 2010;9(1):93-9.
2010: Michael Dame; Narasimharao Bhagavathula; Cohra Mankey; Marissa DaSilva; Tejaswi Paruchuri; Muhammad Nadeem Aslam; James Varani
Human colon tissue in organ culture: preservation of normal and neoplastic characteristics.
In vitro cellular & developmental biology. Animal 2010;46(2):114-22.
2010: Patricia Perone; Stephanie L Weber; Marissa DaSilva; Tejaswi Paruchuri; Narasimharao Bhagavathula; Muhammad Nadeem Aslam; Michael Dame; Kent J Johnson; Richard D Swartz; James Varani
Collagenolytic activity is suppressed in organ-cultured human skin exposed to a gadolinium-based MRI contrast agent.
Investigative radiology 2010;45(1):42-8.
2009: Muhammad Nadeem Aslam; Narasimharao Bhagavathula; Tejaswi Paruchuri; Xin Hu; Subhas Chakrabarty; James Varani
Growth-inhibitory effects of a mineralized extract from the red marine algae, Lithothamnion calcareum, on Ca(2+)-sensitive and Ca(2+)-resistant human colon carcinoma cells.
Cancer letters 2009;283(2):186-92.
2009: Michael Dame; Tejaswi Paruchuri; Marissa DaSilva; Narasimharao Bhagavathula; William Ridder; James Varani
The Göttingen minipig for assessment of retinoid efficacy in the skin: comparison of results from topically treated animals with results from organ-cultured skin.
In vitro cellular & developmental biology. Animal 2009;45(9):551-7.
2009: Narasimharao Bhagavathula; Marissa DaSilva; Muhammad Nadeem Aslam; Michael Dame; Roscoe L Warner; Yiru Xu; Gary J Fisher; Kent J Johnson; Richard D Swartz; James Varani
Regulation of collagen turnover in human skin fibroblasts exposed to a gadolinium-based contrast agent.
Investigative radiology 2009;44(8):433-9.
2009: James Varani; Patricia Perone; Monica O'Brien Deming; Roscoe L Warner; Muhammad Nadeem Aslam; Narasimharao Bhagavathula; Michael Dame; John J Voorhees
Impaired keratinocyte function on matrix metalloproteinase-1 (MMP-1) damaged collagen.
Archives of dermatological research 2009;301(7):497-506.
2009: Narasimharao Bhagavathula; Roscoe L Warner; Marissa DaSilva; Shannon D McClintock; Adam Barron; Muhammad N Aslam; Kent J Johnson; James Varani
A combination of curcumin and ginger extract improves abrasion wound healing in corticosteroid-impaired hairless rat skin.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2009;17(3):360-6.
2009: Guangming Liu; Xin Hu; James Varani; Subhas Chakrabarty
Calcium and calcium sensing receptor modulates the expression of thymidylate synthase, NAD(P)H:quinone oxidoreductase 1 and survivin in human colon carcinoma cells: promotion of cytotoxic response to mitomycin C and fluorouracil.
Molecular carcinogenesis 2009;48(3):202-11.
2009: James Varani; Marissa DaSilva; Roscoe L Warner; Monica O'Brien Deming; Adam G Barron; Kent J Johnson; Richard D Swartz
Effects of gadolinium-based magnetic resonance imaging contrast agents on human skin in organ culture and human skin fibroblasts.
Investigative radiology 2009;44(2):74-81.
2009: Gary J Fisher; Taihao Quan; Trupta Purohit; Yuan Shao; Moon Kyun Cho; Tianyuan He; James Varani; Sewon Kang; John J Voorhees
Collagen fragmentation promotes oxidative stress and elevates matrix metalloproteinase-1 in fibroblasts in aged human skin.
The American journal of pathology 2009;174(1):101-14.
2008: Michael Dame; James Varani
Recombinant collagen for animal product-free dextran microcarriers.
In vitro cellular & developmental biology. Animal 2008;44(10):407-14.
2008: Michael Dame; Diana M Spahlinger; Marissa DaSilva; Patricia Perone; Robert W Dunstan; James Varani
Establishment and characteristics of Gottingen minipig skin in organ culture and monolayer cell culture: relevance to drug safety testing.
In vitro cellular & developmental biology. Animal 2008;44(7):245-52.
2008: James Varani; Patricia Perone; Roscoe L Warner; Michael Dame; Sewon Kang; Gary J Fisher; John J Voorhees
Vascular tube formation on matrix metalloproteinase-1-damaged collagen.
British journal of cancer 2008;98(10):1646-52.
2008: Gary J Fisher; James Varani; John J Voorhees
Looking older: fibroblast collapse and therapeutic implications.
Archives of dermatology 2008;144(5):666-72.
2008: Narasimharao Bhagavathula; Kamalakar C Nerusu; Andrew W Hanosh; Muhammad Nadeem Aslam; Thomas B Sundberg; Anthony William Opipari Jr; Kent J Johnson; Sewon Kang; Gary D Glick; James Varani
7-Chloro-5-(4-hydroxyphenyl)-1-methyl-3-(naphthalen-2-ylmethyl)-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one (Bz-423), a benzodiazepine, suppresses keratinocyte proliferation and has antipsoriatic activity in the human skin-severe, combined immunodeficient mouse transplant model.
The Journal of pharmacology and experimental therapeutics 2008;324(3):938-47.
2008: Roscoe L Warner; Narasimharao Bhagavathula; Kamalakar Nerusu; Andrew W Hanosh; Shannon D McClintock; Madhav K Naik; Kent J Johnson; Isaac Ginsburg; James Varani
MDI 301, a nonirritating retinoid, improves abrasion wound healing in damaged/atrophic skin.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2008;16(1):117-24.
2008: James Varani; Narasimharao Bhagavathula; Muhammad Nadeem Aslam; Kevin Fay; Roscoe L Warner; Andrew W Hanosh; Adam G Barron; Richard A Miller
Inhibition of retinoic acid-induced skin irritation in calorie-restricted mice.
Archives of dermatological research 2008;300(1):27-35.
2007: Narasimharao Bhagavathula; Andrew W Hanosh; Kamalakar C Nerusu; Henry D Appelman; Subhas Chakrabarty; James Varani
Regulation of E-cadherin and beta-catenin by Ca2+ in colon carcinoma is dependent on calcium-sensing receptor expression and function.
International journal of cancer. Journal international du cancer 2007;121(7):1455-62.
2007: Kamalakar C Nerusu; Roscoe L Warner; Narasimharao Bhagavathula; Shannon D McClintock; Kent J Johnson; James Varani
Matrix metalloproteinase-3 (stromelysin-1) in acute inflammatory tissue injury.
Experimental and molecular pathology 2007;83(2):169-76.
2007: James Varani; Patricia Perone; Diana M Spahlinger; Lisa M Singer; Kelly L Diegel; Walter F Bobrowski; Robert W Dunstan
Human skin in organ culture and human skin cells (keratinocytes and fibroblasts) in monolayer culture for assessment of chemically induced skin damage.
Toxicologic pathology 2007;35(5):693-701.
2007: Reza Kafi; Heh Shin R Kwak; Wendy E Schumacher; Soyun Cho; Valerie N Hanft; Ted A Hamilton; Anya L King; Jacqueline D Neal; James Varani; Gary J Fisher; John J Voorhees; Sewon Kang
Improvement of naturally aged skin with vitamin A (retinol).
Archives of dermatology 2007;143(5):606-12.
2007: Jörg Reichrath; B Lehmann; Carsten Carlberg; James Varani; Christos Zouboulis
Vitamins as hormones.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2007;39(2):71-84.
2007: Frank Wang; Luis Garza; Sewon Kang; James Varani; Jeffrey S Orringer; Gary J Fisher; John J Voorhees
In vivo stimulation of de novo collagen production caused by cross-linked hyaluronic acid dermal filler injections in photodamaged human skin.
Archives of dermatology 2007;143(2):155-63.
2007: James Varani; Kevin Fay; Patricia Perone
MDI 301, a non-irritating retinoid, induces changes in human skin that underlie repair.
Archives of dermatological research 2007;298(9):439-48.
2006: James Varani; Narasimharao Bhagavathula; Charles Ellis; Harrihar A Pershadsingh
Thiazolidinediones: potential as therapeutics for psoriasis and perhaps other hyperproliferative skin disease.
Expert opinion on investigational drugs 2006;15(11):1453-68.
2006: James Varani; Michael Dame; Laure Rittie; Suzanne E G Fligiel; Sewon Kang; Gary J Fisher; John J Voorhees
Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation.
The American journal of pathology 2006;168(6):1861-8.
2006: Suzanne E G Fligiel; Theodore J Standiford; Helene Fligiel; Donald P Tashkin; Robert M Strieter; Roscoe L Warner; Kent J Johnson; James Varani
Matrix metalloproteinases and matrix metalloproteinase inhibitors in acute lung injury.
Human pathology 2006;37(4):422-30.
2006: Laure Rittie; James Varani; Sewon Kang; John J Voorhees; Gary J Fisher
Retinoid-induced epidermal hyperplasia is mediated by epidermal growth factor receptor activation via specific induction of its ligands heparin-binding EGF and amphiregulin in human skin in vivo.
The Journal of investigative dermatology 2006;126(4):732-9.
2006: Muhammad Nadeem Aslam; Ephraim Philip Lansky; James Varani
Pomegranate as a cosmeceutical source: pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells.
Journal of ethnopharmacology 2006;103(3):311-8.
2005: Narasimharao Bhagavathula; E A Kelley; M Reddy; Kamalakar C Nerusu; C Leonard; Kevin Fay; Subhas Chakrabarty; James Varani
Upregulation of calcium-sensing receptor and mitogen-activated protein kinase signalling in the regulation of growth and differentiation in colon carcinoma.
British journal of cancer 2005;93(12):1364-71.
2005: Narasimharao Bhagavathula; Kamalakar C Nerusu; Mahendranath Reddy; Charles Ellis; Amar G Chittiboyina; Mitchell Avery; Harrihar A Pershadsingh; theodore kurtz; James Varani
BP-1107 [{2-[4-(2,4-dioxo-thiazolidin-5-ylmethyl)-phenoxy]-ethyl}-methyl-amide]: a novel synthetic thiazolidinedione that inhibits epidermal hyperplasia in psoriatic skin-severe-combined immunodeficient mouse transplants after topical application.
The Journal of pharmacology and experimental therapeutics 2005;315(3):996-1004.
2005: Taskin Yucel; Amar Mutnal; Kevin Fay; Suzanne E G Fligiel; Timothy S Wang; Timothy M Johnson; Shan R Baker; James Varani
Matrix metalloproteinase expression in basal cell carcinoma: relationship between enzyme profile and collagen fragmentation pattern.
Experimental and molecular pathology 2005;79(2):151-60.
2005: Humaira Lateef; Muhammad Nadeem Aslam; Martin J Stevens; James Varani
Pretreatment of diabetic rats with lipoic acid improves healing of subsequently-induced abrasion wounds.
Archives of dermatological research 2005;297(2):75-83.
2005: Nathan Monhian; Brian Jewett; Shan R Baker; James Varani
Matrix metalloproteinase expression in normal skin associated with basal cell carcinoma and in distal skin from the same patients.
Archives of facial plastic surgery 2005;7(4):238-43.
2005: James Varani; Humaira Lateef; Kevin Fay; James T Elder
Antagonism of epidermal growth factor receptor tyrosine kinase ameliorates the psoriatic phenotype in organ-cultured skin.
Skin pharmacology and physiology 2005;18(3):123-31.
2005: Narasimharao Bhagavathula; Kamalakar C Nerusu; Gary J Fisher; Gao Liu; Archana B Thakur; Lorraine Gemmell; Shankar Kumar; Zenghai H Xu; Paul R Hinton; Naoya Tsurushita; Nicholas F Landolfi; John J Voorhees; James Varani
Amphiregulin and epidermal hyperplasia: amphiregulin is required to maintain the psoriatic phenotype of human skin grafts on severe combined immunodeficient mice.
The American journal of pathology 2005;166(4):1009-16.
2005: James Varani; Narasimharao Bhagavathula; Kamalakar C Nerusu; Hilary Sherzer; Kevin Fay; Anthony E Boitano; Gary D Glick; Kent J Johnson; Sewon Kang; Anthony William Opipari Jr
A novel benzodiazepine selectively inhibits keratinocyte proliferation and reduces retinoid-induced epidermal hyperplasia in organ-cultured human skin.
The Journal of pharmacology and experimental therapeutics 2005;313(1):56-63.
2005: Muhammad Nadeem Aslam; Helene Fligiel; Humaira Lateef; Gary J Fisher; Isaac Ginsburg; James Varani
PADMA 28: a multi-component herbal preparation with retinoid-like dermal activity but without epidermal effects.
The Journal of investigative dermatology 2005;124(3):524-9.
2005: Humaira Lateef; Omorodola I Abatan; Muhammad Nadeem Aslam; Martin J Stevens; James Varani
Topical pretreatment of diabetic rats with all-trans retinoic acid improves healing of subsequently induced abrasion wounds.
Diabetes 2005;54(3):855-61.
2005: Subhas Chakrabarty; Hongmei Wang; Lucie Canaff; Geoffrey N Hendy; Henry D Appelman; James Varani
Calcium sensing receptor in human colon carcinoma: interaction with Ca(2+) and 1,25-dihydroxyvitamin D(3).
Cancer research 2005;65(2):493-8.
2004: Roscoe L Warner; Nicholas W Lukacs; Steven D Shapiro; Narasimharao Bhagarvathula; Kamalakar C Nerusu; James Varani; Kent J Johnson
Role of metalloelastase in a model of allergic lung responses induced by cockroach allergen.
The American journal of pathology 2004;165(6):1921-30.
2004: James Varani; Elizabeth A Kelley; Patricia Perone; Humaira Lateef
Retinoid-induced epidermal hyperplasia in human skin organ culture: inhibition with soy extract and soy isoflavones.
Experimental and molecular pathology 2004;77(3):176-83.
2004: Virginia C L Appleyard; Mary A O'Neill; Karen E Murray; Susan E Bray; George Thomson; Neil M Kernohan; James Varani; Jian Zhang; Alastair Thompson
Activity of MDI-301, a novel synthetic retinoid, in xenografts.
Anti-cancer drugs 2004;15(10):991-6.
2004: Roscoe L Warner; Harry C Winter; Cecilia L Speyer; James Varani; Irwin J Oldstein; Hedwig S Murphy; Kent J Johnson
Marasmius oreades lectin induces renal thrombotic microangiopathic lesions.
Experimental and molecular pathology 2004;77(2):77-84.
2004: James Varani
Epithelial cell invasion of the stroma in human skin organ culture.
Frontiers in bioscience : a journal and virtual library 2004;9():2989-95.
2004: Meenakshi S Venkatraman; Amar G Chittiboyina; Josef G Meingassner; Christopher I Ho; James Varani; Charles Ellis; Mitchell A Avery; Harrihar A Pershadsingh; theodore kurtz; Stephen C Benson
Alpha-Lipoic acid-based PPARgamma agonists for treating inflammatory skin diseases.
Archives of dermatological research 2004;296(3):97-104.
2004: Humaira Lateef; Martin J Stevens; James Varani
All-trans-retinoic acid suppresses matrix metalloproteinase activity and increases collagen synthesis in diabetic human skin in organ culture.
The American journal of pathology 2004;165(1):167-74.
2004: James Varani; Lucia Schuger; Michael Dame; Christina Leonard; Suzanne E G Fligiel; Sewon Kang; Gary J Fisher; John J Voorhees
Reduced fibroblast interaction with intact collagen as a mechanism for depressed collagen synthesis in photodamaged skin.
The Journal of investigative dermatology 2004;122(6):1471-9.
2004: Roscoe L Warner; Narasimharao Bhagavathula; Kamalakar C Nerusu; Humaira Lateef; Ellen M Younkin; Kent J Johnson; James Varani
Matrix metalloproteinases in acute inflammation: induction of MMP-3 and MMP-9 in fibroblasts and epithelial cells following exposure to pro-inflammatory mediators in vitro.
Experimental and molecular pathology 2004;76(3):189-95.
2004: Narasimharao Bhagavathula; Kamalakar C Nerusu; Ashish Lal; Charles Ellis; Amar G Chittiboyina; Mitchell A Avery; Christopher I Ho; Stephen C Benson; Harrihar A Pershadsingh; theodore kurtz; James Varani
Rosiglitazone inhibits proliferation, motility, and matrix metalloproteinase production in keratinocytes.
The Journal of investigative dermatology 2004;122(1):130-9.
2003: Michael Dame; Xinwen Yu; Rosario Garrido; Walter F Bobrowski; J Eric McDuffie; Hedwig S Murphy; Mudher Albassam; James Varani
A stepwise method for the isolation of endothelial cells and smooth muscle cells from individual canine coronary arteries.
In vitro cellular & developmental biology. Animal 2003;39(10):402-6.
2003: James Varani; Helene Fligiel; Jian Zhang; Muhammad Nadeem Aslam; Yi Lu; Lindsay A Dehne; Evan T Keller
Separation of retinoid-induced epidermal and dermal thickening from skin irritation.
Archives of dermatological research 2003;295(6):255-62.
2003: Meghan Brennan; Humaa Bhatti; Kamalakar C Nerusu; Narasimharao Bhagavathula; Sewon Kang; Gary J Fisher; James Varani; John J Voorhees
Matrix metalloproteinase-1 is the major collagenolytic enzyme responsible for collagen damage in UV-irradiated human skin.
Photochemistry and photobiology 2003;78(1):43-8.
2003: Yukari Hattori; Kamalakar C Nerusu; Narasimharao Bhagavathula; Meghan Brennan; Noboru Hattori; Hedwig S Murphy; Lyndon D Su; Timothy S Wang; Timothy M Johnson; James Varani
Vascular expression of matrix metalloproteinase-13 (collagenase-3) in basal cell carcinoma.
Experimental and molecular pathology 2003;74(3):230-7.
2003: Suzanne E G Fligiel; James Varani; Subhash C Datta; Sewon Kang; Gary J Fisher; John J Voorhees
Collagen degradation in aged/photodamaged skin in vivo and after exposure to matrix metalloproteinase-1 in vitro.
The Journal of investigative dermatology 2003;120(5):842-8.
2003: Randall N Knibbs; Michael Dame; Melissa R Allen; Yunhong Ding; William Hillegas; James Varani; Lloyd M Stoolman
Sustained high-yield production of recombinant proteins in transiently transfected COS-7 cells grown on trimethylamine-coated (hillex) microcarrier beads.
Biotechnology progress 2003;19(1):9-13.
2003: Subhas Chakrabarty; Venugopal Radjendirane; Henry D Appelman; James Varani
Extracellular calcium and calcium sensing receptor function in human colon carcinomas: promotion of E-cadherin expression and suppression of beta-catenin/TCF activation.
Cancer research 2003;63(1):67-71.
2002: James Varani; Patricia Perone; Matthew G Merfert; Sang Eun Moon; Dennis Larkin; Martin J Stevens
All-trans retinoic acid improves structure and function of diabetic rat skin in organ culture.
Diabetes 2002;51(12):3510-6.
2002: Gary J Fisher; Sewon Kang; James Varani; Zsuzsanna Bata-Csorgo; Yinsheng Wan; Subhash Datta; John J Voorhees
Mechanisms of photoaging and chronological skin aging.
Archives of dermatology 2002;138(11):1462-70.
2002: Sang Eun Moon; Narasimharao Bhagavathula; James Varani
Keratinocyte stimulation of matrix metalloproteinase-1 production and proliferation in fibroblasts: regulation through mitogen-activated protein kinase signalling events.
British journal of cancer 2002;87(4):457-64.
2002: James Varani; Patricia Perone; Suzanne E G Fligiel; Gary J Fisher; John J Voorhees
Inhibition of type I procollagen production in photodamage: correlation between presence of high molecular weight collagen fragments and reduced procollagen synthesis.
The Journal of investigative dermatology 2002;119(1):122-9.
2002: James Varani; Jerzy Petryniak; Masaru Takagaki; Michael Dame; Bronislawa Petryniak; Irwin J Goldstein
Differential expression of an alpha-galactosyl-containing trisaccharide on high- and low-malignant murine sarcoma cells: identification and regulation.
Clinical & experimental metastasis 2002;19(1):1-8.
2001: James Varani; ME Zeigler; Michael Dame; Sewon Kang; Gary J Fisher; John J Voorhees; Stefan Stoll; James T Elder
Heparin-binding epidermal-growth-factor-like growth factor activation of keratinocyte ErbB receptors Mediates epidermal hyperplasia, a prominent side-effect of retinoid therapy.
The Journal of investigative dermatology 2001;117(6):1335-41.
2001: Sang Eun Moon; Michael Dame; D R Remick; James T Elder; James Varani
Induction of matrix metalloproteinase-1 (MMP-1) during epidermal invasion of the stroma in human skin organ culture: keratinocyte stimulation of fibroblast MMP-1 production.
British journal of cancer 2001;85(10):1600-5.
2001: ME Zeigler; Y Chi; D B Tumas; Sarah C Bodary; H Tang; James Varani
Anti-CD11a ameliorates disease in the human psoriatic skin-SCID mouse transplant model: comparison of antibody to CD11a with Cyclosporin A and clobetasol propionate.
Laboratory investigation; a journal of technical methods and pathology 2001;81(9):1253-61.
2001: Roscoe L Warner; CS Lewis; L Beltran; Ellen M Younkin; James Varani; Kent J Johnson
The role of metalloelastase in immune complex-induced acute lung injury.
The American journal of pathology 2001;158(6):2139-44.
2001: Roscoe L Warner; L Beltran; Ellen M Younkin; CS Lewis; Stephen J Weiss; James Varani; Kent J Johnson
Role of stromelysin 1 and gelatinase B in experimental acute lung injury.
American journal of respiratory cell and molecular biology 2001;24(5):537-44.
2001: James Varani; Yukari Hattori; Michael Dame; T Schmidt; Hedwig S Murphy; Kent J Johnson; Kirk J Wojno
Matrix metalloproteinases (MMPs) in fresh human prostate tumour tissue and organ-cultured prostate tissue: levels of collagenolytic and gelatinolytic MMPs are low, variable and different in fresh tissue versus organ-cultured tissue.
British journal of cancer 2001;84(8):1076-83.
2001: James Varani; D Spearman; Patricia Perone; Suzanne E G Fligiel; Subhash C Datta; ZQ Wang; Yuan Shao; Sewon Kang; Gary J Fisher; John J Voorhees
Inhibition of type I procollagen synthesis by damaged collagen in photoaged skin and by collagenase-degraded collagen in vitro.
The American journal of pathology 2001;158(3):931-42.
2001: Bruce L Riser; James Varani; Pedro Cortes; Jerry Yee; Michael Dame; AK Sharba
Cyclic stretching of mesangial cells up-regulates intercellular adhesion molecule-1 and leukocyte adherence: a possible new mechanism for glomerulosclerosis.
The American journal of pathology 2001;158(1):11-7.
2000: Jin Ho Chung; Sewon Kang; James Varani; J Lin; Gary J Fisher; John J Voorhees
Decreased extracellular-signal-regulated kinase and increased stress-activated MAP kinase activities in aged human skin in vivo.
The Journal of investigative dermatology 2000;115(2):177-82.
2000: Roscoe L Warner; NM Bless; CS Lewis; Ellen M Younkin; L Beltran; R Guo; Kent J Johnson; James Varani
Time-dependent inhibition of immune complex-induced lung injury by catalase: relationship to alterations in macrophage and neutrophil matrix metalloproteinase elaboration.
Free radical biology & medicine 2000;29(1):8-16.
2000: Charles Ellis; James Varani; Gary J Fisher; ME Zeigler; Harrihar A Pershadsingh; Stephen C Benson; Y Chi; theodore kurtz
Troglitazone improves psoriasis and normalizes models of proliferative skin disease: ligands for peroxisome proliferator-activated receptor-gamma inhibit keratinocyte proliferation.
Archives of dermatology 2000;136(5):609-16.
2000: James Varani; Roscoe L Warner; Mehrnaz Gharaee-Kermani; Sem H Phan; Sewon Kang; Jin Ho Chung; ZQ Wang; Subhash C Datta; Gary J Fisher; John J Voorhees
Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin.
The Journal of investigative dermatology 2000;114(3):480-6.
2000: James Varani; Yukari Hattori; Y Chi; T Schmidt; Patricia Perone; ME Zeigler; Darrell J Fader; Timothy M Johnson
Collagenolytic and gelatinolytic matrix metalloproteinases and their inhibitors in basal cell carcinoma of skin: comparison with normal skin.
British journal of cancer 2000;82(3):657-65.
1999: A Tavakkol; James Varani; James T Elder; Christos Zouboulis
Maintenance of human skin in organ culture: role for insulin-like growth factor-1 receptor and epidermal growth factor receptor.
Archives of dermatological research 1999;291(12):643-51.
1999: Isaac Ginsburg; Peter A Ward; James Varani
Can we learn from the pathogenetic strategies of group A hemolytic streptococci how tissues are injured and organs fail in post-infectious and inflammatory sequelae?
FEMS immunology and medical microbiology 1999;25(4):325-38.
1999: Isaac Ginsburg; Milu Sadovnic; James Varani; Oren Tirosh; Ron Kohen
Hemolysis of human red blood cells induced by the combination of diethyldithiocarbamate (DDC) and divalent metals: modulation by anaerobiosis, certain antioxidants and oxidants.
Free radical research 1999;31(2):79-91.
1999: Hedwig S Murphy; Roscoe L Warner; N Bakopoulos; Michael Dame; James Varani; Peter A Ward
Endothelial cell determinants of susceptibility to neutrophil-mediated killing.
Shock (Augusta, Ga.) 1999;12(2):111-7.
1999: ME Zeigler; Y Chi; T Schmidt; James Varani
Role of ERK and JNK pathways in regulating cell motility and matrix metalloproteinase 9 production in growth factor-stimulated human epidermal keratinocytes.
Journal of cellular physiology 1999;180(2):271-84.
1999: James Varani; Michael Dame; Kirk J Wojno; Lucia Schuger; Kent J Johnson
Characteristics of nonmalignant and malignant human prostate in organ culture.
Laboratory investigation; a journal of technical methods and pathology 1999;79(6):723-31.
1999: DF Gibbs; Thomas P Shanley; Roscoe L Warner; Hedwig S Murphy; James Varani; Kent J Johnson
Role of matrix metalloproteinases in models of macrophage-dependent acute lung injury. Evidence for alveolar macrophage as source of proteinases.
American journal of respiratory cell and molecular biology 1999;20(6):1145-54.
1999: DF Gibbs; Roscoe L Warner; Stephen J Weiss; Kent J Johnson; James Varani
Characterization of matrix metalloproteinases produced by rat alveolar macrophages.
American journal of respiratory cell and molecular biology 1999;20(6):1136-44.
1999: Isaac Ginsburg; M Sadovnik; S Sallon; I Milo-Goldzweig; Urij Rampampam; Aviva Breuer; D Gibbs; James Varani; S Roberts; E Cleator; N Singh
PADMA-28, a traditional tibetan herbal preparation inhibits the respiratory burst in human neutrophils, the killing of epithelial cells by mixtures of oxidants and pro-inflammatory agonists and peroxidation of lipids.
Inflammopharmacology 1999;7(1):47-62.
1998: James Varani; F Piel; S Josephs; Ted F Beals; William Hillegas
Attachment and growth of anchorage-dependent cells on a novel, charged-surface microcarrier under serum-free conditions.
Cytotechnology 1998;28(1-3):101-9.
1998: Hedwig S Murphy; N Bakopoulos; Michael Dame; James Varani; Peter A Ward
Heterogeneity of vascular endothelial cells: differences in susceptibility to neutrophil-mediated injury.
Microvascular research 1998;56(3):203-11.
1998: James Varani; Gary J Fisher; Sewon Kang; John J Voorhees
Molecular mechanisms of intrinsic skin aging and retinoid-induced repair and reversal.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 1998;3(1):57-60.
1998: James Varani
Preservation of human skin structure and function in organ culture.
Histology and histopathology 1998;13(3):775-83.
1998: Y Chi; ME Zeigler; J Walker; Patricia Perone; Subhash C Datta; James Varani
Elaboration of matrix metalloproteinase inhibitors by human skin in organ culture and by skin cells in monolayer culture: relationship to invasion.
Invasion & metastasis 1998;18(1):27-34.
1998: James Varani; Sewon Kang; Stefan Stoll; James T Elder
Human psoriatic skin in organ culture: comparison with normal skin exposed to exogenous growth factors and effects of an antibody to the EGF receptor.
Pathobiology : journal of immunopathology, molecular and cellular biology 1998;66(6):253-9.
1997: Gary J Fisher; ZQ Wang; Subhash C Datta; James Varani; Sewon Kang; John J Voorhees
Pathophysiology of premature skin aging induced by ultraviolet light.
The New England journal of medicine 1997;337(20):1419-28.
1997: Isaac Ginsburg; Saul Yedgar; James Varani
Diethyldithiocarbamate and nitric oxide synergize with oxidants and with membrane-damaging agents to injure mammalian cells.
Free radical research 1997;27(2):143-64.
1997: James Varani; ME Zeigler; Patricia Perone; Thomas Carey; Subhash C Datta
Human squamous carcinoma cell invasion in organ-cultured skin.
Cancer letters 1997;111(1-2):51-7.
1996: James Varani; Ronald B Hirschl; Michael Dame; Kent J Johnson
Perfluorocarbon protects lung epithelial cells from neutrophil-mediated injury in an in vitro model of liquid ventilation therapy.
Shock (Augusta, Ga.) 1996;6(5):339-44.
1996: James Varani; Michael Dame; M Diaz; Lloyd M Stoolman
Deferoxamine interferes with adhesive functions of activated human neutrophils.
Shock (Augusta, Ga.) 1996;5(6):395-401.
1996: James Varani; W Burmeister; M R Bleavins; Kent J Johnson
All-trans retinoic acid reduces membrane fluidity of human dermal fibroblasts. Assessment by fluorescence redistribution after photobleaching.
The American journal of pathology 1996;148(4):1307-12.
1996: Gary J Fisher; Subhash C Datta; H S Talwar; Z Q Wang; James Varani; Sewon Kang; John J Voorhees
Molecular basis of sun-induced premature skin ageing and retinoid antagonism.
Nature 1996;379(6563):335-9.
1996: James Varani; S Josephs; William Hillegas
Human diploid fibroblast growth on polystyrene microcarriers in aggregates.
Cytotechnology 1996;22(1-3):111-7.
1996: ME Zeigler; N T Dutcheshen; D F Gibbs; James Varani
Growth factor-induced epidermal invasion of the dermis in human skin organ culture: expression and role of matrix metalloproteinases.
Invasion & metastasis 1996;16(1):11-8.
1996: ME Zeigler; S Krause; S Karmiol; James Varani
Growth factor-induced epidermal invasion of the dermis in human skin organ culture: dermal invasion correlated with epithelial cell motility.
Invasion & metastasis 1996;16(1):3-10.
1995: James Varani; Michael Dame; C G Taylor; J Vidya Sarma; R Merino; R G Kunkel; Gabriel Nunez; Xiaodong Huang
Age-dependent injury in human umbilical vein endothelial cells: relationship to apoptosis and correlation with a lack of A20 expression.
Laboratory investigation; a journal of technical methods and pathology 1995;73(6):851-8.
1995: Fumitaka Numa; Kei Hirabayashi; N Tsunaga; Hiroshi Kato; K O'Rourke; H Shao; C Stechmann-Lebakken; James Varani; A Rapraeger; V M Dixit
Elevated levels of syndecan-1 expression confer potent serum-dependent growth in human 293T cells.
Cancer research 1995;55(20):4676-80.
1995: James Varani; B Burmeister; Patricia Perone; M Bleavins; Kent J Johnson
All-trans retinoic acid inhibits fluctuations in intracellular Ca2+ resulting from changes in extracellular Ca2+.
The American journal of pathology 1995;147(3):718-27.
1995: James Varani; S E Fligiel; D R Inman; T F Beals; William Hillegas
Modulation of adhesive properties of DEAE-dextran with laminin.
Journal of biomedical materials research 1995;29(8):993-7.
1995: Z Song; James Varani; Irwin J Goldstein
Expression and function of beta 1 integrins on adherent and nonadherent Ehrlich ascites tumor cells.
Experimental cell research 1995;218(1):96-104.
1995: James Varani; Michael Dame
Injury to adult human dermal microvascular endothelial cells in vitro.
Shock (Augusta, Ga.) 1995;3(3):179-83.
1995: James Varani; D Trinh; Thomas Carey; Monica Liebert; M J Wheelock
Expression of cell surface adhesion molecules on the epithelium of Organ-cultured skin.
Invasion & metastasis 1995;15(5-6):189-96.
1995: James Varani; Patricia Perone; D R Inman; W Burmeister; S B Schollenberger; S E Fligiel; Robert G Sitrin; Kent J Johnson
Human skin in organ culture. Elaboration of proteolytic enzymes in the presence and absence of exogenous growth factors.
The American journal of pathology 1995;146(1):210-7.
1995: Paul E McKeever; James Varani; S M Papadopoulos; M Wang; J P McCoy
Products of cells from gliomas: IX. Evidence that two fundamentally different mechanisms change extracellular matrix expression by gliomas.
Journal of neuro-oncology 1995;24(3):267-80.
1994: S Huang; James Varani; S Chakrabarty
Control of AKR fibroblast phenotype by fibronectin: regulation of cell-surface fibronectin binding receptor by fibronectin.
Journal of cellular physiology 1994;161(3):470-82.
1994: James Varani; Patricia Perone; Christopher E M Griffiths; D R Inman; S E Fligiel; John J Voorhees
All-trans retinoic acid (RA) stimulates events in organ-cultured human skin that underlie repair. Adult skin from sun-protected and sun-exposed sites responds in an identical manner to RA while neonatal foreskin responds differently.
The Journal of clinical investigation 1994;94(5):1747-56.
1994: James Varani; Peter A Ward
Mechanisms of endothelial cell injury in acute inflammation.
Shock (Augusta, Ga.) 1994;2(5):311-9.
1994: D K Shumaker; M D Sklar; Edward V Prochownik; James Varani
Increased cell-substrate adhesion accompanies conditional reversion to the normal phenotype in ras-oncogene-transformed NIH-3T3 cells.
Experimental cell research 1994;214(2):440-6.
1994: James Varani; B Burmeister; Robert G Sitrin; S B Shollenberger; D R Inman; S E Fligiel; D F Gibbs; Kent J Johnson
Expression of serine proteinases and metalloproteinases in organ-cultured human skin. Altered levels in the presence of retinoic acid and possible relationship to retinoid-induced loss of epidermal cohesion.
The American journal of pathology 1994;145(3):561-73.
1994: C G Taylor; Michael Dame; Hedwig S Murphy; Peter A Ward; James Varani
Spontaneous injury to human umbilical vein endothelial cells increases during in vitro culture and is blocked by protein kinase activation.
Laboratory investigation; a journal of technical methods and pathology 1994;70(6):822-9.
1994: Brian J Nickoloff; Raj S Mitra; James Varani; Xiaodong Huang; Peter J Polverini
Aberrant production of interleukin-8 and thrombospondin-1 by psoriatic keratinocytes mediates angiogenesis.
The American journal of pathology 1994;144(4):820-8.
1994: James Varani; Peter A Ward
Mechanisms of neutrophil-dependent and neutrophil-independent endothelial cell injury.
Biological signals 1994;3(1):1-14.
1994: James Varani; Patricia Perone; S E Fligiel; D R Inman; John J Voorhees
all-trans-retinoic acid preserves viability of fibroblasts and keratinocytes in full-thickness human skin and fibroblasts in isolated dermis in organ culture.
Archives of dermatological research 1994;286(8):443-7.
1993: Michael S Mulligan; P E Desrochers; Arul M Chinnaiyan; D F Gibbs; James Varani; Kent J Johnson; Stephen J Weiss
In vivo suppression of immune complex-induced alveolitis by secretory leukoproteinase inhibitor and tissue inhibitor of metalloproteinases 2.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(24):11523-7.
1993: Z Song; James Varani; Irwin J Goldstein
Differences in cell surface carbohydrates, and in laminin and fibronectin synthesis, between adherent and non-adherent Ehrlich ascites tumor cells.
International journal of cancer. Journal international du cancer 1993;55(6):1029-35.
1993: James Varani; D R Inman; Patricia Perone; S E Fligiel; John J Voorhees
Retinoid toxicity for fibroblasts and epithelial cells is separable from growth promoting activity.
The Journal of investigative dermatology 1993;101(6):839-42.
1993: Lucia Schuger; James Varani; R Mitra; Kevin Gilbride
Retinoic acid stimulates mouse lung development by a mechanism involving epithelial-mesenchymal interaction and regulation of epidermal growth factor receptors.
Developmental biology 1993;159(2):462-73.
1993: Peter A Ward; James Varani
Mechanisms of neutrophil-mediated injury.
Clinical and experimental immunology 1993;93 Suppl 1():2.
1993: James Varani; B K Larson; Patricia Perone; D R Inman; S E Fligiel; John J Voorhees
All-trans retinoic acid and extracellular Ca2+ differentially influence extracellular matrix production by human skin in organ culture.
The American journal of pathology 1993;142(6):1813-22.
1993: Isaac Ginsburg; R Misgav; D F Gibbs; James Varani; Ron Kohen
Chemiluminescence in activated human neutrophils: role of buffers and scavengers.
Inflammation 1993;17(3):227-43.
1993: Isaac Ginsburg; R S Mitra; D F Gibbs; James Varani; Ron Kohen
Killing of endothelial cells and release of arachidonic acid. Synergistic effects among hydrogen peroxide, membrane-damaging agents, cationic substances, and proteinases and their modulation by inhibitors.
Inflammation 1993;17(3):295-319.
1993: Isaac Ginsburg; James Varani
Interaction of viable group A streptococci and hydrogen peroxide in killing of vascular endothelial cells.
Free radical biology & medicine 1993;14(5):495-500.
1993: Michael S Mulligan; G P Wilson; Robert F Todd III; C W Smith; D C Anderson; James Varani; T B Issekutz; M Miyasaka; T Tamatani; M Myasaka
Role of beta 1, beta 2 integrins and ICAM-1 in lung injury after deposition of IgG and IgA immune complexes.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(6):2407-17.
1993: Lloyd M Stoolman; T L Wang; R Situ; James Varani
Regulation of fibronectin and laminin binding activity in cultured human lymphoblastic cell lines.
Journal of cellular physiology 1993;154(3):593-600.
1993: R Situ; D R Inman; S E Fligiel; James Varani
Effects of all-trans-retinoic acid on melanocyte adhesion and motility.
Dermatology (Basel, Switzerland) 1993;186(1):38-44.
1993: James Varani; S E Fligiel; Lucia Schuger; Patricia Perone; D Inman; Christopher E M Griffiths; John J Voorhees
Effects of all-trans retinoic acid and Ca++ on human skin in organ culture.
The American journal of pathology 1993;142(1):189-98.
1993: James Varani; S E Fligiel; Patricia Perone; D R Inman; John J Voorhees
Effects of sodium lauryl sulfate on human skin in organ culture: comparison with all-trans-retinoic acid and epidermal growth factor.
Dermatology (Basel, Switzerland) 1993;187(1):19-25.
1993: S E Fligiel; James Varani
In situ epithelial cell invasion in organ culture.
Invasion & metastasis 1993;13(5):225-33.
1993: James Varani; D R Inman; S E Fligiel; William Hillegas
Use of recombinant and synthetic peptides as attachment factors for cells on microcarriers.
Cytotechnology 1993;13(2):89-98.
1992: A R Huber; S Ellis; Kent J Johnson; V M Dixit; James Varani
Monocyte diapedesis through an in vitro vessel wall construct: inhibition with monoclonal antibodies to thrombospondin.
Journal of leukocyte biology 1992;52(5):524-8.
1992: James Varani; C G Taylor; Bruce L Riser; D K Shumaker; K Y Yeh; Michael Dame; D F Gibbs; Robert F Todd III; Francis Dumler; Jonathan Bromberg
Mesangial cell killing by leukocytes: role of leukocyte oxidants and proteolytic enzymes.
Kidney international 1992;42(5):1169-77.
1992: Isaac Ginsburg; R Misgav; A Pinson; James Varani; Peter A Ward; Ron Kohen
Synergism among oxidants, proteinases, phospholipases, microbial hemolysins, cationic proteins, and cytokines.
Inflammation 1992;16(5):519-38.
1992: Lucia Schuger; James Varani; Paul D Killen; A P Skubitz; Kevin Gilbride
Laminin expression in the mouse lung increases with development and stimulates spontaneous organotypic rearrangement of mixed lung cells.
Developmental dynamics : an official publication of the American Association of Anatomists 1992;195(1):43-54.
1992: James Varani; Michael Dame; D F Gibbs; C G Taylor; Joel M Weinberg; J Shayevitz; Peter A Ward
Human umbilical vein endothelial cell killing by activated neutrophils. Loss of sensitivity to injury is accompanied by decreased iron content during in vitro culture and is restored with exogenous iron.
Laboratory investigation; a journal of technical methods and pathology 1992;66(6):708-14.
1992: Michael S Mulligan; James Varani; Jeffrey S Warren; Gerd O Till; C W Smith; D C Anderson; Robert F Todd III; Peter A Ward
Roles of beta 2 integrins of rat neutrophils in complement- and oxygen radical-mediated acute inflammatory injury.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(6):1847-57.
1992: Joel M Weinberg; James Varani; Kent J Johnson; N F Roeser; Michael Dame; J A Davis; Manjeri Venkatachalam
Protection of human umbilical vein endothelial cells by glycine and structurally similar amino acids against calcium and hydrogen peroxide-induced lethal cell injury.
The American journal of pathology 1992;140(2):457-71.
1992: S E Fligiel; D R Inman; H S Talwar; Gary J Fisher; John J Voorhees; James Varani
Modulation of growth in normal and malignant melanocytic cells by all-trans retinoic acid.
Journal of cutaneous pathology 1992;19(1):27-33.
1992: James Varani; D R Inman; D F Gibbs; S E Fligiel; John J Voorhees
Modulation of Ca2+ levels in keratinocytes by all-trans retinoic acid.
Pathobiology : journal of immunopathology, molecular and cellular biology 1992;60(2):93-9.
1992: Kent J Johnson; James Varani; J E Smolen
Neutrophil activation and function in health and disease.
Immunology series 1992;57():1-46.
1992: R C Rao; James Varani; H Kaz Soong
FGF promotes corneal stromal fibroblast motility.
Journal of ocular pharmacology 1992;8(1):77-81.
1992: James Varani; Robert G Sitrin; William Hillegas
Expression of plasminogen activator and plasminogen activator inhibitor mRNA in human fibroblasts grown on different substrates.
Cytotechnology 1992;9(1-3):157-62.
1991: Joel M Weinberg; Manjeri Venkatachalam; N F Roeser; J A Davis; James Varani; Kent J Johnson
Amino acid protection of cultured kidney tubule cells against calcium ionophore-induced lethal cell injury.
Laboratory investigation; a journal of technical methods and pathology 1991;65(6):671-8.
1991: James Varani; A Astrom; Christopher E M Griffiths; John J Voorhees
Induction of proliferation of growth-inhibited keratinocytes and fibroblasts in monolayer culture by sodium lauryl sulfate: comparison with all-trans retinoic acid.
The Journal of investigative dermatology 1991;97(5):917-21.
1991: J Petryniak; James Varani; P R Ervin; Irwin J Goldstein
Differential expression of glycoproteins containing alpha-D-galactosyl groups on normal human breast epithelial cells and MCF-7 human breast carcinoma cells.
Cancer letters 1991;60(1):59-65.
1991: James Varani; J Jones; Michael Dame; C Sulavik; D F Gibbs; Kent J Johnson
Effects of all-trans retinoic acid on neutrophil-mediated endothelial cell injury in vitro and immune complex injury in rats.
The American journal of pathology 1991;139(4):901-9.
1991: Michael S Mulligan; James Varani; Michael Dame; C L Lane; C W Smith; D C Anderson; Peter A Ward
Role of endothelial-leukocyte adhesion molecule 1 (ELAM-1) in neutrophil-mediated lung injury in rats.
The Journal of clinical investigation 1991;88(4):1396-406.
1991: Lucia Schuger; A P Skubitz; K Sue O'Shea; J F Chang; James Varani
Identification of laminin domains involved in branching morphogenesis: effects of anti-laminin monoclonal antibodies on mouse embryonic lung development.
Developmental biology 1991;146(2):531-41.
1991: James Varani; Isaac Ginsburg; D F Gibbs; P S Mukhopadhyay; C Sulavik; Kent J Johnson; Joel M Weinberg; U S Ryan; Peter A Ward
Hydrogen peroxide-induced cell and tissue injury: protective effects of Mn2+.
Inflammation 1991;15(4):291-301.
1991: James Varani; Lloyd M Stoolman; Timothy S Wang; Lucia Schuger; C Flippen; Michael Dame; Kent J Johnson; Robert F Todd III; U S Ryan; Peter A Ward
Thrombospondin production and thrombospondin-mediated adhesion in U937 cells.
Experimental cell research 1991;195(1):177-82.
1991: J R Shayevitz; James Varani; Peter A Ward; Paul R Knight
Halothane and isoflurane increase pulmonary artery endothelial cell sensitivity to oxidant-mediated injury.
Anesthesiology 1991;74(6):1067-77.
1991: Valerie P Castle; James Varani; S Fligiel; Edward V Prochownik; V Dixit
Antisense-mediated reduction in thrombospondin reverses the malignant phenotype of a human squamous carcinoma.
The Journal of clinical investigation 1991;87(6):1883-8.
1991: James Varani; D F Gibbs; D R Inman; B Shah; S E Fligiel; John J Voorhees
Inhibition of epithelial cell adhesion by retinoic acid. Relationship to reduced extracellular matrix production and alterations in Ca2+ levels.
The American journal of pathology 1991;138(4):887-95.
1991: James Varani; Lucia Schuger; S E Fligiel; D R Inman; S Chakrabarty
Production of fibronectin by human tumor cells and interaction with exogenous fibronectin: comparison of cell lines obtained from colon adenocarcinomas and squamous carcinomas of the upper aerodigestive tract.
International journal of cancer. Journal international du cancer 1991;47(3):421-5.
1991: Peter A Ward; Jeffrey S Warren; James Varani; Kent J Johnson
PAF, cytokines, toxic oxygen products and cell injury.
Molecular aspects of medicine 1991;12(2):169-74.
1991: B J Nickoloff; James Varani; Raj S Mitra
Modulation of keratinocyte biology by gamma interferon: relevance to cutaneous wound healing.
Progress in clinical and biological research 1991;365():141-54.
1991: James Varani; G J Gendimenico; B Shah; D Gibbs; R J Capetola; J A Mezick; John J Voorhees
A direct comparison of pharmacologic effects of retinoids on skin cells in vitro and in vivo.
Skin pharmacology : the official journal of the Skin Pharmacology Society 1991;4(4):254-61.
1990: Lucia Schuger; K Sue O'Shea; B B Nelson; James Varani
Organotypic arrangement of mouse embryonic lung cells on a basement membrane extract: involvement of laminin.
Development (Cambridge, England) 1990;110(4):1091-9.
1990: James Varani; Sem H Phan; D F Gibbs; U S Ryan; Peter A Ward
H2O2-mediated cytotoxicity of rat pulmonary endothelial cells. Changes in adenosine triphosphate and purine products and effects of protective interventions.
Laboratory investigation; a journal of technical methods and pathology 1990;63(5):683-9.
1990: D E Gannon; X M He; Peter A Ward; James Varani; Kent J Johnson
Time-dependent inhibition of oxygen radical induced lung injury.
Inflammation 1990;14(5):509-22.
1990: S Chakrabarty; D Fan; James Varani
Modulation of differentiation and proliferation in human colon carcinoma cells by transforming growth factor beta 1 and beta 2.
International journal of cancer. Journal international du cancer 1990;46(3):493-9.
1990: S Chakrabarty; Y Jan; James Varani
Differentiation-related alterations in the plasma membranes of chemically transformed murine fibroblasts.
Anticancer research 1990;10(5A):1319-28.
1990: T Yamamoto; James Varani; H Kaz Soong; Paul R Lichter
Effects of 5-fluorouracil and mitomycin C on cultured rabbit subconjunctival fibroblasts.
Ophthalmology 1990;97(9):1204-10.
1990: Robert G Sitrin; Margaret R Gyetko; K L Kole; Paul E McKeever; James Varani
Expression of heterogeneous profiles of plasminogen activators and plasminogen activator inhibitors by human glioma lines.
Cancer research 1990;50(16):4957-61.
1990: Peter A Ward; James Varani
Mechanisms of neutrophil-mediated killing of endothelial cells.
Journal of leukocyte biology 1990;48(1):97-102.
1990: James Varani; J Shayevitz; D Perry; Raj S Mitra; Brian J Nickoloff; John J Voorhees
Retinoic acid stimulation of human dermal fibroblast proliferation is dependent on suboptimal extracellular Ca2+ concentration.
The American journal of pathology 1990;136(6):1275-81.
1990: James Varani; S Chakrabarty
Modulation of fibronectin synthesis and fibronectin binding during transformation and differentiation of mouse AKR fibroblasts.
Journal of cellular physiology 1990;143(3):445-54.
1990: James Varani; Raj S Mitra; D Gibbs; Sem H Phan; Xiaodong Huang; R Mitra; Timothy S Wang; K J Siebert; Brian J Nickoloff; John J Voorhees
All-trans retinoic acid stimulates growth and extracellular matrix production in growth-inhibited cultured human skin fibroblasts.
The Journal of investigative dermatology 1990;94(5):717-23.
1990: Lucia Schuger; K Sue O'Shea; J Rheinheimer; James Varani
Laminin in lung development: effects of anti-laminin antibody in murine lung morphogenesis.
Developmental biology 1990;137(1):26-32.
1990: Paul E McKeever; J A Feldenzer; J P McCoy; M Laug; Stephen S Gebarski; William F Chandler; Harry S Greenberg; Larry Junck; Constance J D'Amato; James Varani
Nuclear parameters as prognostic indicators in glioblastoma patients.
Journal of neuropathology and experimental neurology 1990;49(1):71-8.
1990: Lucia Schuger; V M Dixit; Thomas Carey; James Varani
Modulation of squamous carcinoma cell growth, morphology, adhesiveness and extracellular matrix production by interferon-gamma and tumor necrosis factor-alpha.
Pathobiology : journal of immunopathology, molecular and cellular biology 1990;58(5):279-86.
1990: B A Markey; Sem H Phan; James Varani; U S Ryan; Peter A Ward
Inhibition of cytotoxicity by intracellular superoxide dismutase supplementation.
Free radical biology & medicine 1990;9(4):307-14.
1990: Bruce L Riser; James Varani; Brian J Nickoloff; Raj S Mitra; Xiaodong Huang
Thrombospondin binding by keratinocytes: modulation under conditions which alter thrombospondin biosynthesis.
Dermatologica 1990;180(2):60-5.
1989: Bruce L Riser; R Mitra; D Perry; V Dixit; James Varani
Monocyte killing of human squamous epithelial cells: role for thrombospondin.
Cancer research 1989;49(21):6123-9.
1989: Isaac Ginsburg; D F Gibbs; James Varani
Interaction of mammalian cells with polymorphonuclear leukocytes: relative sensitivity to monolayer disruption and killing.
Inflammation 1989;13(5):529-42.
1989: James Varani; Brian J Nickoloff; Xiaodong Huang; Raj S Mitra; John J Voorhees
All-trans retinoic acid stimulates growth of adult human keratinocytes cultured in growth factor-deficient medium, inhibits production of thrombospondin and fibronectin, and reduces adhesion.
The Journal of investigative dermatology 1989;93(4):449-54.
1989: James Varani; Isaac Ginsburg; Lucia Schuger; D F Gibbs; Jonathan Bromberg; Kent J Johnson; U S Ryan; Peter A Ward
Endothelial cell killing by neutrophils. Synergistic interaction of oxygen products and proteases.
The American journal of pathology 1989;135(3):435-8.
1989: S Chakrabarty; Y Jan; A Levine; B McClenic; James Varani
Fibronectin/laminin and their receptors in aberrant growth control in FR3T3 cells transformed by Ha-ras oncogene and epidermal growth factor gene.
International journal of cancer. Journal international du cancer 1989;44(2):325-31.
1989: H Kaz Soong; B McClenic; James Varani; T Hassan; S C Huang; R Brenz
EGF does not enhance corneal epithelial cell motility.
Investigative ophthalmology & visual science 1989;30(8):1808-12.
1989: D Gibbs; James Varani; Isaac Ginsburg
Formation and use of poly-L-histidine-catalase complexes: protection of cells from hydrogen peroxide-mediated injury.
Inflammation 1989;13(4):465-74.
1989: D N Shapiro; James Varani; I Ginsburg
Activation of a murine T-cell hybridoma by cationized bacteria.
Immunology 1989;67(4):478-83.
1989: H Kaz Soong; T Hassan; James Varani; S C Huang; M Brennan
Fibronectin does not enhance epidermal growth factor-mediated acceleration of corneal epithelial wound closure.
Archives of ophthalmology 1989;107(7):1052-4.
1989: Lucia Schuger; James Varani; Rory M Marks; Steven Kunkel; Kent J Johnson; Peter A Ward
Cytotoxicity of tumor necrosis factor-alpha for human umbilical vein endothelial cells.
Laboratory investigation; a journal of technical methods and pathology 1989;61(1):62-8.
1989: Sem H Phan; D E Gannon; James Varani; U S Ryan; Peter A Ward
Xanthine oxidase activity in rat pulmonary artery endothelial cells and its alteration by activated neutrophils.
The American journal of pathology 1989;134(6):1201-11.
1989: Raymond J Hutchinson; S Fligiel; J Appleyard; James Varani; Max S Wicha
Attachment of neuroblastoma cells to extracellular matrix: correlation with metastatic capacity.
The Journal of laboratory and clinical medicine 1989;113(5):561-8.
1989: James Varani; Bruce L Riser; L A Hughes; Thomas Carey; S E Fligiel; V M Dixit
Characterization of thrombospondin synthesis, secretion and cell surface expression by human tumor cells.
Clinical & experimental metastasis 1989;7(3):265-76.
1989: James Varani; S E Fligiel; D R Inman; D L Helmreich; M J Bendelow; William Hillegas
Substrate-dependent differences in production of extracellular matrix molecules by squamous carcinoma cells and diploid fibroblasts.
Biotechnology and bioengineering 1989;33(10):1235-41.
1989: S Chakrabarty; Y Jan; Michael G Brattain; A Tobon; James Varani
Diverse cellular responses elicited from human colon carcinoma cells by transforming growth factor-beta.
Cancer research 1989;49(8):2112-7.
1989: K A Laybourn; J C Hiserodt; James Varani
Laminin receptor expression on murine tumor cells: correlation with sensitivity to natural cell-mediated cytotoxicity.
International journal of cancer. Journal international du cancer 1989;43(4):737-42.
1989: Peter A Ward; Jeffrey S Warren; G O Till; James Varani; Kent J Johnson
Modification of disease by preventing free radical formation: a new concept in pharmacological intervention.
Baillière's clinical haematology 1989;2(2):391-402.
1989: Isaac Ginsburg; Peter A Ward; James Varani
Lysophosphatides enhance superoxide responses of stimulated human neutrophils.
Inflammation 1989;13(2):163-74.
1989: James Varani; Raj S Mitra; B J McClenic; S E Fligiel; D R Inman; Xiaodong Huang; Brian J Nickoloff
Modulation of fibronectin production in normal human melanocytes and malignant melanoma cells by interferon-gamma and tumor necrosis factor-alpha.
The American journal of pathology 1989;134(4):827-36.
1989: M L Wencel; M L Morganroth; S O Schoeneich; D E Gannon; James Varani; Robert F Todd III; U S Ryan; Laurence A Boxer
Cytoplasts and Mo1-deficient neutrophils pretreated with plasma and LPS induce lung injury.
The American journal of physiology 1989;256(3 Pt 2):H751-9.
1989: B K McClenic; Raj S Mitra; Bruce L Riser; Brian J Nickoloff; Xiaodong Huang; James Varani
Production and utilization of extracellular matrix components by human melanocytes.
Experimental cell research 1989;180(2):314-25.
1989: Paul E McKeever; S E Fligiel; James Varani; R L Castle; T W Hood
Products of cells cultured from gliomas. VII. Extracellular matrix proteins of gliomas which contain glial fibrillary acidic protein.
Laboratory investigation; a journal of technical methods and pathology 1989;60(2):286-95.
1989: Isaac Ginsburg; D F Gibbs; Lucia Schuger; Kent J Johnson; U S Ryan; Peter A Ward; James Varani
Vascular endothelial cell killing by combinations of membrane-active agents and hydrogen peroxide.
Free radical biology & medicine 1989;7(4):369-76.
1988: Isaac Ginsburg; S E Fligiel; Peter A Ward; James Varani
Lipoteichoic acid-antilipoteichoic acid complexes induce superoxide generation by human neutrophils.
Inflammation 1988;12(6):525-48.
1988: James Varani; M J Bendelow; William Hillegas
The effect of substrate on the production of infectious virus by cells in culture.
Journal of biological standardization 1988;16(4):333-8.
1988: G P Frenette; Thomas Carey; James Varani; D R Schwartz; S E Fligiel; RW Ruddon; B P Peters
Biosynthesis and secretion of laminin and laminin-associated glycoproteins by nonmalignant and malignant human keratinocytes: comparison of cell lines from primary and secondary tumors in the same patient.
Cancer research 1988;48(18):5193-202.
1988: Brian J Nickoloff; Raj S Mitra; Bruce L Riser; Xiaodong Huang; James Varani
Modulation of keratinocyte motility. Correlation with production of extracellular matrix molecules in response to growth promoting and antiproliferative factors.
The American journal of pathology 1988;132(3):543-51.
1988: Brian J Nickoloff; Bruce L Riser; Raj S Mitra; Xiaodong Huang; James Varani
Inhibitory effect of gamma interferon on cultured human keratinocyte thrombospondin production, distribution, and biologic activities.
The Journal of investigative dermatology 1988;91(3):213-8.
1988: James Varani; M J Bendelow; D E Sealey; Steven Kunkel; D E Gannon; U S Ryan; Peter A Ward
Tumor necrosis factor enhances susceptibility of vascular endothelial cells to neutrophil-mediated killing.
Laboratory investigation; a journal of technical methods and pathology 1988;59(2):292-5.
1988: S Chakrabarty; A Tobon; James Varani; Michael G Brattain
Induction of carcinoembryonic antigen secretion and modulation of protein secretion/expression and fibronectin/laminin expression in human colon carcinoma cells by transforming growth factor-beta.
Cancer research 1988;48(14):4059-64.
1988: James Varani; Brian J Nickoloff; Bruce L Riser; Raj S Mitra; K O'Rourke; Xiaodong Huang
Thrombospondin-induced adhesion of human keratinocytes.
The Journal of clinical investigation 1988;81(5):1537-44.
1988: I A Grimstad; A K Thorsrud; James Varani; Peter A Ward; Egil Jellum
Marker polypeptide differences between spontaneous strongly and weakly metastatic cancer cells identified by 2-dimensional gel electrophoresis.
International journal of cancer. Journal international du cancer 1988;41(4):568-72.
1988: Bruce L Riser; James Varani; K O'Rourke; Xiaodong Huang
Thrombospondin binding by human squamous carcinoma and melanoma cells: relationship to biological activity.
Experimental cell research 1988;174(2):319-29.
1988: Peter A Ward; Gerd O Till; D E Gannon; James Varani; Kent J Johnson
The role of iron in injury of endothelial cells in vitro and in vivo.
Basic life sciences 1988;49():969-74.
1988: Bruce L Riser; K A Laybourn; James Varani
Treatment of mice with anti-asialo-GM1 antibody or poly-I:C: effects on metastasis dissociable from modulation of macrophage antitumor activity.
Natural immunity and cell growth regulation 1988;7(5-6):305-15.
1987: James Varani; Paul E McKeever; S E Fligiel; Robert G Sitrin
Plasminogen activator production by human tumor cells: effect on tumor cell-extracellular matrix interactions.
International journal of cancer. Journal international du cancer 1987;40(6):772-7.
1987: Isaac Ginsburg; S E Fligiel; R G Kunkel; B L Riser; James Varani
Phagocytosis of Candida albicans enhances malignant behavior of murine tumor cells.
Science (New York, N.Y.) 1987;238(4833):1573-5.
1987: S Chakrabarty; Michael G Brattain; R L Ochs; James Varani
Modulation of fibronectin, laminin, and cellular adhesion in the transformation and differentiation of murine AKR fibroblasts.
Journal of cellular physiology 1987;133(3):415-25.
1987: D E Gannon; James Varani; Sem H Phan; J H Ward; J Kaplan; Gerd O Till; Richard H Simon; U S Ryan; Peter A Ward
Source of iron in neutrophil-mediated killing of endothelial cells.
Laboratory investigation; a journal of technical methods and pathology 1987;57(1):37-44.
1987: James Varani; Thomas Carey; S E Fligiel; Paul E McKeever; V Dixit
Tumor type-specific differences in cell-substrate adhesion among human tumor cell lines.
International journal of cancer. Journal international du cancer 1987;39(3):397-403.
1987: Scott E Kern; D F Keren; T F Beals; James Varani
A model for Paneth cell study: tissue culture of the hyperplastic Paneth cell population of rabbit Thiry-Vella ileal loops.
Advances in experimental medicine and biology 1987;216A():419-26.
1987: Paul E McKeever; T W Hood; James Varani; J A Taren; W H Beierwaltes; Richard L Wahl; Monica Liebert; P K Nguyen
Products of cells cultured from gliomas. V. Cytology and morphometry of two cell types cultured from glioma.
Journal of the National Cancer Institute 1987;78(1):75-84.
1987: James Varani
Interaction of tumor cells with the extracellular matrix.
Revisiones sobre biología celular : RBC 1987;12():1-113.
1986: James Varani; V M Dixit; S E Fligiel; Paul E McKeever; Thomas Carey
Thrombospondin-induced attachment and spreading of human squamous carcinoma cells.
Experimental cell research 1986;167(2):376-90.
1986: James Varani; M J Bendelow; J H Chun; William Hillegas
Cell growth on microcarriers: comparison of proliferation on and recovery from various substrates.
Journal of biological standardization 1986;14(4):331-6.
1986: S E Fligiel; K A Laybourn; B P Peters; R W Ruddon; J C Hiserodt; James Varani
Laminin production by murine melanoma cells: possible involvement in cell motility.
Clinical & experimental metastasis 1986;4(4):259-72.
1986: James Varani; Jeffrey D Hasday; Robert G Sitrin; P G Brubaker; William Hillegas
Proteolytic enzymes and arachidonic acid metabolites produced by MRC-5 cells on various microcarrier substrates.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1986;22(10):575-82.
1986: K A Laybourn; J C Hiserodt; L V Abruzzo; James Varani
In vitro and in vivo interaction between murine fibrosarcoma cells and natural killer cells.
Cancer research 1986;46(7):3407-12.
1986: Paul E McKeever; S E Fligiel; James Varani; J L Hudson; D Smith; R L Castle; J P McCoy
Products of cells cultured from gliomas. IV. Extracellular matrix proteins of gliomas.
International journal of cancer. Journal international du cancer 1986;37(6):867-74.
1986: James Varani; S E Fligiel; B Wilson
Motility of rasH oncogene transformed NIH-3T3 cells.
Invasion & metastasis 1986;6(6):335-46.
1986: X M He; S E Fligiel; James Varani
Modulation of tumor cell motility by prostaglandins and inhibitors of prostaglandin synthesis.
Experimental cell biology 1986;54(3):128-37.
1986: A C Batchev; Bruce L Riser; E G Hellner; S E Fligiel; James Varani
Phorbol ester binding and phorbol ester-induced arachidonic acid metabolism in a highly responsive murine fibrosarcoma cell line and in a less-responsive variant.
Clinical & experimental metastasis 1986;4(1):51-61.
1985: James Varani; S E Fligiel; G O Till; R G Kunkel; U S Ryan; Peter A Ward
Pulmonary endothelial cell killing by human neutrophils. Possible involvement of hydroxyl radical.
Laboratory investigation; a journal of technical methods and pathology 1985;53(6):656-63.
1985: J P McCoy; W Schade; G E Merz; T Esch; James Varani; J L Hudson
DNA content of murine fibrosarcoma cell lines with varying metastatic potential.
Cancer research 1985;45(11 Pt 2):5757-61.
1985: R V Lloyd; B S Wilson; James Varani; P K Gaur; S Moline; J G Makari
Immunocytochemical characterization of a monoclonal antibody that recognizes mitosing cells.
The American journal of pathology 1985;121(2):275-83.
1985: J C Hiserodt; K A Laybourn; James Varani
Laminin inhibits the recognition of tumor target cells by murine natural killer (NK) and natural cytotoxic (NC) lymphocytes.
The American journal of pathology 1985;121(1):148-55.
1985: S E Fligiel; Patricia Perone; James Varani
Arachidonic acid metabolism in murine fibrosarcoma cells with differing in vivo and in vitro characteristics.
International journal of cancer. Journal international du cancer 1985;36(3):383-8.
1985: J C Hiserodt; K A Laybourn; James Varani
Expression of a laminin-like substance on the surface of murine natural killer (NK) lymphocytes and its role in NK recognition of tumor target cells.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(2):1484-7.
1985: Sem H Phan; James Varani; D Smith
Rat lung fibroblast collagen metabolism in bleomycin-induced pulmonary fibrosis.
The Journal of clinical investigation 1985;76(1):241-7.
1985: James Varani; S E Fligiel; Patricia Perone
Directional motility in strongly malignant murine tumor cells.
International journal of cancer. Journal international du cancer 1985;35(4):559-64.
1985: Wayne A Marasco; Peter A Ward; D E Feltner; James Varani
Chemotactic factor binding by metastatic tumour cells: evidence for a formyl-peptide receptor on a non-myelogenous cell.
Journal of cell science 1985;73():121-34.
1985: James Varani; I A Grimstad; Randall N Knibbs; T Hovig; J P McCoy
Attachment, spreading and growth in vitro of highly malignant and low malignant murine fibrosarcoma cells.
Clinical & experimental metastasis 1985;3(1):45-59.
1985: James Varani; P Perone
Response of Walker 256 carcinosarcoma cells to 12-O-tetradecanoylphorbol 13-acetate: possible regulation by endogenous cyclooxygenase metabolites.
Journal of the National Cancer Institute 1985;74(1):165-72.
1985: J P McCoy; Irwin J Goldstein; James Varani
A review of studies in our laboratory regarding ELLA methodology for the study of cell surface carbohydrates from tumors of varying metastatic potential.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 1985;6(2):99-114.
1985: S E Fligiel; A F Rodriguez; Randall N Knibbs; J P McCoy; James Varani
Characterization of laminin-stimulated adherence and motility in tumor cells.
Oncology 1985;42(4):265-71.
1985: James Varani; Michael Dame; J Rediske; T F Beals; William Hillegas
Substrate-dependent differences in growth and biological properties of fibroblasts and epithelial cells grown in microcarrier culture.
Journal of biological standardization 1985;13(1):67-76.
1984: I A Grimstad; James Varani; J P McCoy
Contribution of alpha-D-galactopyranosyl end groups to attachment of highly and low metastatic murine fibrosarcoma cells to various substrates.
Experimental cell research 1984;155(2):345-58.
1984: P R Clarke; James Varani
Phorbol ester binding to chemotactically responding and nonresponding Walker 256 carcinosarcoma cells.
Cancer research 1984;44(11):4967-71.
1984: R Situ; E C Lee; J P McCoy; James Varani
Stimulation of murine tumour cell motility by laminin.
Journal of cell science 1984;70():167-76.
1984: S E Fligiel; E C Lee; J P McCoy; Kent J Johnson; James Varani
Protein degradation following treatment with hydrogen peroxide.
The American journal of pathology 1984;115(3):418-25.
1984: H L Malinoff; J P McCoy; James Varani; Max S Wicha
Metastatic potential of murine fibrosarcoma cells is influenced by cell surface laminin.
International journal of cancer. Journal international du cancer 1984;33(5):651-5.
1984: J P McCoy; James Varani; Irwin J Goldstein
Enzyme-linked lectin assay (ELLA). II. Detection of carbohydrate groups on the surface of unfixed cells.
Experimental cell research 1984;151(1):96-103.
1984: Alvin R Jr Solomon; J E Rasmussen; James Varani; C L Pierson
The Tzanck smear in the diagnosis of cutaneous herpes simplex.
JAMA : the journal of the American Medical Association 1984;251(5):633-5.
1984: E C Lee; R S Tu; Joseph C Fantone III; James Varani
Functional responses of tumor cells to phorbol esters: role for prostaglandins.
Oncology 1984;41(3):210-6.
1984: U Desai; B Dickey; James Varani; Donald L Kreutzer
Demonstration of C5 cleaving activity in bronchoalveolar fluids and cells: a mechanism of acute and chronic alveolitis.
Journal of experimental pathology 1984;1(3):201-16.
1984: J P McCoy; R V Lloyd; Max S Wicha; James Varani
Identification of a laminin-like substance on the surface of high-malignant murine fibrosarcoma cells.
Journal of cell science 1984;65():139-51.
1983: James Varani; E J Lovett; Max S Wicha; H Malinoff; J P McCoy
Cell surface alpha-D-galactopyranosyl end groups: use as markers in the isolation of murine tumor cell lines with different cancer-causing potentials.
Journal of the National Cancer Institute 1983;71(6):1281-7.
1983: James Varani; Michael Dame; T F Beals; J A Wass
Growth of three established cell lines on glass microcarriers.
Biotechnology and bioengineering 1983;25(5):1359-72.
1983: James Varani; J A Wass; K M Rao
Actin changes in normal human and rat leukocytes and in transformed human leukocytic cells.
Journal of the National Cancer Institute 1983;70(5):805-9.
1983: J P McCoy; James Varani; Irwin J Goldstein
Enzyme-linked lectin assay (ELLA): use of alkaline phosphatase-conjugated Griffonia simplicifolia B4 isolectin for the detection of alpha-D-galactopyranosyl end groups.
Analytical biochemistry 1983;130(2):437-44.
1983: James Varani; E J Lovett; J P McCoy; S Shibata; D E Maddox; Irwin J Goldstein; Max S Wicha
Differential expression of a lamininlike substance by high- and low-metastatic tumor cells.
The American journal of pathology 1983;111(1):27-34.
1983: J P McCoy; D Schrier; E J Lovett; W John Judd; James Varani
Hyperimmune human ABO blood-typing sera: reactivity with murine laminin and cytotoxicity for metastatic murine tumour cells.
Journal of cell science 1983;59():245-56.
1983: James Varani; Peter A Ward
Chemotaxis of tumor cells.
Agents and actions. Supplements 1983;12():134-51.
1983: Joseph C Fantone III; L J Elgas; L Weinberger; James Varani
Modulation of tumor cell adherence by prostaglandins.
Oncology 1983;40(6):421-6.
1983: E J Lovett; James Varani; J Lundy
Suppressor cells and increased primary tumor growth rate induced by thiopental.
Journal of surgical oncology 1983;22(1):26-32.
1982: K M Rao; James Varani
Actin polymerization induced by chemotactic peptide and concanavalin A in rat neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 1982;129(4):1605-7.
1982: James Varani; D Ward; Kent J Johnson
Nonspecific protease and elastase activities in rat leukocytes.
Inflammation 1982;6(2):177-87.
1982: James Varani; E J Lovett
Phenotypic stability of murine tumor cells in vitro and in vivo.
Journal of the National Cancer Institute 1982;68(6):957-62.
1982: James Varani
Chemotaxis of metastatic tumor cells.
Cancer metastasis reviews 1982;1(1):17-28.
1982: F W Orr; James Varani
Chemotactic mechanisms and cancer metastasis.
Pathology annual 1982;17 Pt 2():307-30.
1982: James Varani; Joseph C Fantone III
Phorbol myristate acetate-induced adherence of Walker 256 carcinosarcoma cells.
Cancer research 1982;42(1):190-7.
1982: Salwa Elgebaly; Steven Kunkel; E J Lovett; James Varani
CAMP differences between clones of high and low malignant fibrosarcoma cells.
Oncology 1982;39(3):163-6.
1981: J A Wass; James Varani; G E Piontek; Peter A Ward; F W Orr
Responses of normal and malignant cells to collagen, collagen-derived peptides and the C5-related tumor cell chemotactic peptide.
Cell differentiation 1981;10(6):329-32.
1981: Kent J Johnson; James Varani
Substrate hydrolysis by immune complex-activated neutrophils: effect of physical presentation of complexes and protease inhibitors.
Journal of immunology (Baltimore, Md. : 1950) 1981;127(5):1875-9.
1981: W C Lam; Edward Delikatny; F W Orr; J Wass; James Varani; Peter A Ward
The chemotactic response of tumor cells. A model for cancer metastasis.
The American journal of pathology 1981;104(1):69-76.
1981: James Varani; J Wass; G Piontek; Peter A Ward
Chemotactic factor-induced adherence of tumor cells.
Cell biology international reports 1981;5(5):525-30.
1981: J A Wass; James Varani; G E Piontek; D Goff; Peter A Ward
Characteristics of the chemotactic factor-mediated cell swelling response of tumor cells.
Journal of the National Cancer Institute 1981;66(5):927-33.
1981: F W Orr; James Varani; J Delikatny; N Jain; Peter A Ward
Comparison of the chemotactic responsiveness of two fibrosarcoma subpopulations of differing malignancy.
The American journal of pathology 1981;102(2):160-7.
1981: James Varani; E J Lovett; J Lundy
A model of tumor cell dormancy: effects of anesthesia and surgery.
Journal of surgical oncology 1981;17(1):9-14.
1981: F W Orr; W C Lam; Edward Delikatny; S Mokashi; James Varani
Localization of intravenously injected tumor cells in the rat mesentery after intraperitoneal administration of chemotactic stimuli.
Invasion & metastasis 1981;1(4):239-47.
1980: D A Gabrielson; J J Kelleher; James Varani
Effect of Corynebacterium granulosum immunopotentiation on the pathogenesis of herpes simplex virus type 2 in BALB/c mice.
Infection and immunity 1980;30(3):791-6.
1980: James Varani; E J Lovett; Salwa Elgebaly; J Lundy; Peter A Ward
In vitro and in vivo adherence of tumor cell variants correlated with tumor formation.
The American journal of pathology 1980;101(2):345-52.
1980: James Varani; Kent J Johnson; J Kaplan
Development of a solid-phase assay for measurement of proteolytic enzyme activity.
Analytical biochemistry 1980;107(2):377-84.
1980: J A Wass; James Varani; Peter A Ward
Size increase induced in Walker ascites cells by chemotactic factors.
Cancer letters 1980;9(4):313-8.
1980: James Varani; W Orr; Peter A Ward
Adhesive characteristics of tumor cell variants of high and low tumorigenic potential.
Journal of the National Cancer Institute 1980;64(5):1173-8.
1980: F W Orr; James Varani; M D Gondek; Peter A Ward; G R Mundy
Partial characterization of a bone-derived chemotactic factor for tumor cells.
The American journal of pathology 1980;99(1):43-52.
1979: James Varani; W Orr; Peter A Ward
Hydrolytic enzyme activities, migratory activity, and in vivo growth and metastatic potential of recent tumor isolates.
Cancer research 1979;39(7 Pt 1):2376-80.
1979: Kent J Johnson; James Varani; J Oliver; Peter A Ward
Immunologic vasculitis in beige mice with deficiency of leukocytic neutral protease.
Journal of immunology (Baltimore, Md. : 1950) 1979;122(5):1807-11.
1979: James Varani; W Orr; Peter A Ward
Cell-associated proteases affect tumour cell migration in vitro.
Journal of cell science 1979;36():241-52.
1979: James Varani; W Orr; Peter A Ward
Comparison of subpopulations of tumor cells with altered migratory activity, attachment characteristics, enzyme levels and in vivo behavior.
European journal of cancer 1979;15(4):585-92.
1979: W Orr; Sem H Phan; James Varani; Peter A Ward; D L Kreutzer; R O Webster; P M Henson
Chemotactic factor for tumor cells derived from the C5a fragment of complement component C5.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(4):1986-9.
1979: W Orr; James Varani; M K Gondex; Peter A Ward; G R Mundy
Chemotactic responses of tumor cells to products of resorbing bone.
Science (New York, N.Y.) 1979;203(4376):176-9.
1979: F W Orr; James Varani; D L Kreutzer; R M Senior; Peter A Ward
Digestion of the fifth component of complement by leukocyte enzymes. Sequential generation of chemotactic activities for leukocytes and for tumor cells.
The American journal of pathology 1979;94(1):75-83.
1978: James Varani; W Orr; Peter A Ward
Comparison of cell attachment and caseinolytic activities of five tumour cell types.
Journal of cell science 1978;34():133-44.
1978: W Orr; James Varani; Peter A Ward
Characteristics of the chemotactic response of neoplastic cells to a factor derived from the fifth component of complement.
The American journal of pathology 1978;93(2):405-22.
1978: G R Mundy; James Varani; W Orr; M D Gondek; Peter A Ward
Resorbing bone is chemotactic for monocytes.
Nature 1978;275(5676):132-5.
1978: James Varani; W Orr; Peter A Ward
A comparison of the migration patterns of normal and malignant cells in two assay systems.
The American journal of pathology 1978;90(1):159-72.
1976: J J Kelleher; James Varani
Photoinactivation of latent herpes simplex virus in rabbit kidney cells.
Antimicrobial agents and chemotherapy 1976;10(2):229-33.
1975: James Varani; J J Kelleher
Effects of 5-bromodeoxyuridine and 5-iododeoxyuridine on a latent herpes simplex virus infection.
Antimicrobial agents and chemotherapy 1975;8(1):18-21.
1975: J J Kelleher; James Varani; W W Nelson
Establishment of a nonproductive herpes simplex virus infection in rabbit kidney cells.
Infection and immunity 1975;12(1):128-33.