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Teppo Varilo

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Finland

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Tiia M Luukkonen; Aarno Palotie; Minna Pöyhönen; Riitta Salonen; Joseph D Terwilliger; Pekka Ellonen; Sonja Lagström; Joseph H Lee; Teppo Varilo
A balanced translocation truncates Neurotrimin in a family with intracranial and thoracic aortic aneurysm.
Emma S Nyman; Susan L Smalley; Anja Taanila; Teppo Varilo; Tuula Hurtig; Marjo-Riitta Järvelin; Sandra Loo; Anu Loukola; James J McGough; Irma Moilanen; Stanley F Nelson; Leena Peltonen
Sex-specific influence of DRD2 on ADHD-type temperament in a large population-based birth cohort.
Ritva Haataja; Minna K Karjalainen; Aino Luukkonen; Kari Teramo; Hilkka Puttonen; Marja Ojaniemi; Teppo Varilo; Bimal P Chaudhari; Jevon Plunkett; Jeffrey C Murray; Steven A McCarroll; Leena Peltonen; Louis J Muglia; Aarno Palotie; Mikko Hallman
Mapping a new spontaneous preterm birth susceptibility gene, IGF1R, using linkage, haplotype sharing, and association analysis.

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All Publications

2012: Tiia M Luukkonen; Aarno Palotie; Minna Pöyhönen; Riitta Salonen; Joseph D Terwilliger; Pekka Ellonen; Sonja Lagström; Joseph H Lee; Teppo Varilo
A balanced translocation truncates Neurotrimin in a family with intracranial and thoracic aortic aneurysm.
Journal of medical genetics 2012;49(10):621-9.
2012: Emma S Nyman; Susan L Smalley; Anja Taanila; Teppo Varilo; Tuula Hurtig; Marjo-Riitta Järvelin; Sandra Loo; Anu Loukola; James J McGough; Irma Moilanen; Stanley F Nelson; Leena Peltonen
Sex-specific influence of DRD2 on ADHD-type temperament in a large population-based birth cohort.
Psychiatric genetics 2012;22(4):197-201.
2011: Ritva Haataja; Minna K Karjalainen; Aino Luukkonen; Kari Teramo; Hilkka Puttonen; Marja Ojaniemi; Teppo Varilo; Bimal P Chaudhari; Jevon Plunkett; Jeffrey C Murray; Steven A McCarroll; Leena Peltonen; Louis J Muglia; Aarno Palotie; Mikko Hallman
Mapping a new spontaneous preterm birth susceptibility gene, IGF1R, using linkage, haplotype sharing, and association analysis.
PLoS genetics 2011;7(2):e1001293.
2010: Jenni Lahtela; Heidi O Nousiainen; Vedran Stefanovic; Jonna Tallila; Heli Viskari; Riitta Karikoski; Massimiliano Gentile; Carola Saloranta; Teppo Varilo; Riitta Salonen; Marjo Kestilä
Mutant CHUK and severe fetal encasement malformation.
The New England journal of medicine 2010;363(17):1631-7.
2010: Juho Wedenoja; Annamari Tuulio-Henriksson; Jaana Suvisaari; Anu Loukola; Tiina Paunio; Timo Partonen; Teppo Varilo; Jouko Lönnqvist; Leena Peltonen
Replication of association between working memory and Reelin, a potential modifier gene in schizophrenia.
Biological psychiatry 2010;67(10):983-91.
2010: Outi M Palo; Pia Soronen; Kaisa Silander; Teppo Varilo; Katja Tuononen; Tuula Kieseppä; Timo Partonen; Jouko Lönnqvist; Tiina Paunio; Leena Peltonen
Identification of susceptibility loci at 7q31 and 9p13 for bipolar disorder in an isolated population.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(3):723-35.
2010: Eveliina Jakkula; Virpi Leppä; Anna-Maija Sulonen; Teppo Varilo; Suvi Kallio; Anu Kemppinen; Shaun Purcell; Keijo Koivisto; Pentti J Tienari; Marja-Liisa Sumelahti; Irina Elovaara; Tuula Pirttilä; Mauri Reunanen; Arpo Aromaa; Annette Bang Oturai; Helle Bach Søndergaard; Hanne F Harbo; Inger-Lise Mero; Stacey B Gabriel; Daniel B Mirel; Stephen L Hauser; Ludwig Kappos; Chris Polman; Philip L De Jager; David A Hafler; Mark J Daly; Aarno Palotie; Janna Saarela; Leena Peltonen
Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene.
American journal of human genetics 2010;86(2):285-91.
2009: Emma S Nyman; Anu Loukola; Teppo Varilo; Jesper Ekelund; Juha Veijola; Matti Joukamaa; Anja Taanila; Anneli Pouta; Jouko Miettunen; Nelson Freimer; Marjo-Riitta Järvelin; Leena Peltonen
Impact of the dopamine receptor gene family on temperament traits in a population-based birth cohort.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(6):854-65.
2009: Tiina Paunio; Ritva Arajärvi; Joseph D Terwilliger; Tero Hiekkalinna; Perttu Haimi; Timo Partonen; Jouko Lönnqvist; Leena Peltonen; Teppo Varilo
Linkage analysis of schizophrenia controlling for population substructure.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(6):827-35.
2009: Helena Kilpinen; Tero Ylisaukko-Oja; Karola Rehnström; Emilia Gaál; Joni A Turunen; Elli Kempas; Lennart von Wendt; Teppo Varilo; Leena Peltonen
Linkage and linkage disequilibrium scan for autism loci in an extended pedigree from Finland.
Human molecular genetics 2009;18(15):2912-21.
2009: Chiara Sabatti; Susan K Service; Anna-Liisa Hartikainen; Anneli Pouta; Samuli Ripatti; Jae Brodsky; Chris G Jones; Noah A Zaitlen; Teppo Varilo; Marika Kaakinen; Ulla Sovio; Aimo Ruokonen; Jaana Laitinen; Eveliina Jakkula; Lachlan Coin; Clive Hoggart; ANDREW COLLINS; Hannu Turunen; Stacey Gabriel; Paul Elliot; Mark I McCarthy; Mark J Daly; Marjo-Riitta Järvelin; Nelson B Freimer; Leena Peltonen
Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
Nature genetics 2009;41(1):35-46.
2008: J Wedenoja; Anu Loukola; Annamari Tuulio-Henriksson; Tiina Paunio; Jesper Ekelund; Kaisa Silander; Teppo Varilo; K Heikkilä; Jaana Suvisaari; Timo Partonen; Jouko Lönnqvist; Leena Peltonen
Replication of linkage on chromosome 7q22 and association of the regional Reelin gene with working memory in schizophrenia families.
Molecular psychiatry 2008;13(7):673-84.
2008: H Kilpinen; Tero Ylisaukko-Oja; William Hennah; Outi M Palo; Teppo Varilo; Raija Vanhala; Taina Nieminen-von Wendt; Lennart von Wendt; Tiina Paunio; Leena Peltonen
Association of DISC1 with autism and Asperger syndrome.
Molecular psychiatry 2008;13(2):187-96.
2007: Emma S Nyman; Matthew N Ogdie; Anu Loukola; Teppo Varilo; Anja Taanila; Tuula Hurtig; Irma Moilanen; Sandra K Loo; James J McGough; Marjo-Riitta Järvelin; Susan L Smalley; Stanley F Nelson; Leena Peltonen
ADHD candidate gene study in a population-based birth cohort: association with DBH and DRD2.
Journal of the American Academy of Child and Adolescent Psychiatry 2007;46(12):1614-21.
2007: Susan L Smalley; James J McGough; Irma Moilanen; Sandra K Loo; Anja Taanila; Hanna Ebeling; Tuula Hurtig; Marika Kaakinen; Lorie A Humphrey; James T McCracken; Teppo Varilo; May H Yang; Stanley F Nelson; Leena Peltonen; Marjo-Riitta Järvelin
Prevalence and psychiatric comorbidity of attention-deficit/hyperactivity disorder in an adolescent Finnish population.
Journal of the American Academy of Child and Adolescent Psychiatry 2007;46(12):1575-83.
2007: Joni A Turunen; Juho O Peltonen; Olli P H Pietiläinen; William Hennah; Anu Loukola; Tiina Paunio; Kaisa Silander; Jesper Ekelund; Teppo Varilo; Timo Partonen; Jouko Lönnqvist; Leena Peltonen
The role of DTNBP1, NRG1, and AKT1 in the genetics of schizophrenia in Finland.
Schizophrenia research 2007;91(1-3):27-36.
2006: Susan K Service; Joseph DeYoung; Maria Karayiorgou; J Louw Roos; Herman Pretorious; Gabriel Bedoya; Jorge Ospina; Andres Ruiz-Linares; antonio macedo; Joana Almeida Palha; Peter Heutink; Yurii Aulchenko; Ben Oostra; C.M. Duijn; Marjo-Riitta Jarvelin; Teppo Varilo; Lynette Peddle; Proton Rahman; Giovanna Piras; Maria Monne; Sarah Murray; Luana Galver; Leena Peltonen; Chiara Sabatti; ANDREW COLLINS; Nelson B Freimer
Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies.
Nature genetics 2006;38(5):556-60.
2006: Ritva Arajärvi; Teppo Varilo; Jari Haukka; Jaana Suvisaari; Jaana Suokas; Hannu Juvonen; Maria Muhonen; Kirsi Suominen; Jukka Hintikka; Marjut Schreck; Annamari Tuulio-Henriksson; Timo Partonen; Jouko Lönnqvist
Affective flattening and alogia associate with the familial form of schizophrenia.
Psychiatry research 2006;141(2):161-72.
2006: Mikko Kuokkanen; Jorma Kokkonen; Nabil Sabri Enattah; Tero Ylisaukko-Oja; Hanna Komu; Teppo Varilo; Leena Peltonen; Erkki Savilahti; Irma Jarvela
Mutations in the translated region of the lactase gene (LCT) underlie congenital lactase deficiency.
American journal of human genetics 2006;78(2):339-44.
2005: William Hennah; Annamari Tuulio-Henriksson; Tiina Paunio; Jesper Ekelund; Teppo Varilo; Timo Partonen; Tyrone D Cannon; Jouko Lönnqvist; Leena Peltonen
A haplotype within the DISC1 gene is associated with visual memory functions in families with a high density of schizophrenia.
Molecular psychiatry 2005;10(12):1097-103.
2005: Anna H Hakonen; Silja Heiskanen; Vesa Juvonen; Ilse Lappalainen; Petri Luoma; Maria Rantamaki; Gert Van Goethem; Ann Lofgren; Peter Hackman; Anders Paetau; Seppo Kaakkola; Kari Majamaa; Teppo Varilo; Bjarne Udd; Helena Kaariainen; Laurence A Bindoff; Anu Suomalainen
Mitochondrial DNA polymerase W748S mutation: a common cause of autosomal recessive ataxia with ancient European origin.
American journal of human genetics 2005;77(3):430-41.
2004: Tiina Paunio; Annamari Tuulio-Henriksson; Tero Hiekkalinna; Markus Perola; Teppo Varilo; Timo Partonen; Tyrone D Cannon; Jouko Lönnqvist; Leena Peltonen
Search for cognitive trait components of schizophrenia reveals a locus for verbal learning and memory on 4q and for visual working memory on 2q.
Human molecular genetics 2004;13(16):1693-702.
2004: Teppo Varilo; Leena Peltonen
Isolates and their potential use in complex gene mapping efforts.
Current opinion in genetics & development 2004;14(3):316-23.
2004: Ritva Arajärvi; Jari Haukka; Teppo Varilo; Jaana Suokas; Hannu Juvonen; Jaana Suvisaari; Maria Muhonen; Kirsi Suominen; Annamari Tuulio-Henriksson; Marjut Schreck; Iiris Hovatta; Timo Partonen; Jouko Lönnqvist
Clinical phenotype of schizophrenia in a Finnish isolate.
Schizophrenia research 2004;67(2-3):195-205.
2004: Tero Ylisaukko-Oja; Taina Nieminen-von Wendt; Elli Kempas; Susan Sarenius; Teppo Varilo; Lennart von Wendt; Leena Peltonen; Irma Järvelä
Genome-wide scan for loci of Asperger syndrome.
Molecular psychiatry 2004;9(2):161-8.
2004: William Hennah; Teppo Varilo; Tiina Paunio; Leena Peltonen
Haplotype analysis and identification of genes for a complex trait: examples from schizophrenia.
Annals of medicine 2004;36(5):322-31.
2003: William Hennah; Teppo Varilo; Marjo Kestilä; Tiina Paunio; Ritva Arajärvi; Jari Haukka; Alex Parker; Rory Martin; Steve Levitzky; Timo Partonen; Joanne Meyer; Jouko Lönnqvist; Leena Peltonen; Jesper Ekelund
Haplotype transmission analysis provides evidence of association for DISC1 to schizophrenia and suggests sex-dependent effects.
Human molecular genetics 2003;12(23):3151-9.
2003: Mari Auranen; Teppo Varilo; Reija Alen; Raija Vanhala; K Ayers; Elli Kempas; Tero Ylisaukko-Oja; Leena Peltonen; Irma Järvelä
Evidence for allelic association on chromosome 3q25-27 in families with autism spectrum disorders originating from a subisolate of Finland.
Molecular psychiatry 2003;8(10):879-84.
2003: Annamari Tuulio-Henriksson; Ritva Arajärvi; Timo Partonen; Jari Haukka; Teppo Varilo; Marjut Schreck; Tyrone Cannon; Jouko Lönnqvist
Familial loading associates with impairment in visual span among healthy siblings of schizophrenia patients.
Biological psychiatry 2003;54(6):623-8.
2003: Heikki Mannila; M Koivisto; Markus Perola; Teppo Varilo; William Hennah; Jesper Ekelund; M Lukk; Leena Peltonen; Esko Ukkonen
Minimum description length block finder, a method to identify haplotype blocks and to compare the strength of block boundaries.
American journal of human genetics 2003;73(1):86-94.
2003: Eva Forsman; Susanna Lemmelä; Teppo Varilo; Paula Kristo; Henrik Forsius; Eeva-Marja Sankila; Irma Järvelä
The role of TIGR and OPTN in Finnish glaucoma families: a clinical and molecular genetic study.
Molecular vision 2003;9():217-22.
2003: M Koivisto; Markus Perola; Teppo Varilo; William Hennah; Jesper Ekelund; M Lukk; Leena Peltonen; Esko Ukkonen; Heikki Mannila
An MDL method for finding haplotype blocks and for estimating the strength of haplotype block boundaries.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 2003;():502-13.
2003: Teppo Varilo; Tiina Paunio; Alex Parker; Markus Perola; Joanne Meyer; Joseph D Terwilliger; Leena Peltonen
The interval of linkage disequilibrium (LD) detected with microsatellite and SNP markers in chromosomes of Finnish populations with different histories.
Human molecular genetics 2003;12(1):51-9.
2002: Mari Auranen; Raija Vanhala; Teppo Varilo; Kristin Ayers; Elli Kempas; Tero Ylisaukko-Oja; Janet S Sinsheimer; Leena Peltonen; Irma Järvelä
A genomewide screen for autism-spectrum disorders: evidence for a major susceptibility locus on chromosome 3q25-27.
American journal of human genetics 2002;71(4):777-90.
2002: Annamari Tuulio-Henriksson; Jari Haukka; Timo Partonen; Teppo Varilo; Tiina Paunio; Jesper Ekelund; Tyrone D Cannon; Joanne M Meyer; Jouko Lönnqvist
Heritability and number of quantitative trait loci of neurocognitive functions in families with schizophrenia.
American journal of medical genetics 2002;114(5):483-90.
2002: Jenny Ekholm; P Pekkarinen; Päivi Pajukanta; Tuula Kieseppä; Timo Partonen; Tiina Paunio; Teppo Varilo; Markus Perola; Jouko Lönnqvist; Leena Peltonen
Bipolar disorder susceptibility region on Xq24-q27.1 in Finnish families.
Molecular psychiatry 2002;7(5):453-9.
2001: Tiina Paunio; Jesper Ekelund; Teppo Varilo; Alex Parker; Iiris Hovatta; Joni A Turunen; K Rinard; A Foti; Joseph D Terwilliger; Hannu Juvonen; Jaana Suvisaari; Ritva Arajärvi; Jaana Suokas; Timo Partonen; Jouko Lönnqvist; Joanne Meyer; Leena Peltonen
Genome-wide scan in a nationwide study sample of schizophrenia families in Finland reveals susceptibility loci on chromosomes 2q and 5q.
Human molecular genetics 2001;10(26):3037-48.
2001: Jari Haukka; Jaana Suvisaari; Teppo Varilo; Jouko Lönnqvist
Regional variation in the incidence of schizophrenia in Finland: a study of birth cohorts born from 1950 to 1969.
Psychological medicine 2001;31(6):1045-53.
2001: Jesper Ekelund; Iiris Hovatta; Alex Parker; Tiina Paunio; Teppo Varilo; R Martin; J Suhonen; Pekka Ellonen; G Chan; Janet S Sinsheimer; Eric Sobel; Hannu Juvonen; Ritva Arajärvi; Timo Partonen; Jaana Suvisaari; Jouko Lönnqvist; Joanne Meyer; Leena Peltonen
Chromosome 1 loci in Finnish schizophrenia families.
Human molecular genetics 2001;10(15):1611-7.
2001: Mari Auranen; Raija Vanhala; M Vosman; M Levander; Teppo Varilo; M Hietala; Raili Riikonen; Leena Peltonen; Irma Järvelä
MECP2 gene analysis in classical Rett syndrome and in patients with Rett-like features.
Neurology 2001;56(5):611-7.
2000: Teppo Varilo; Maris Laan; Iiris Hovatta; Victor Wiebe; Joseph D Terwilliger; Leena Peltonen
Linkage disequilibrium in isolated populations: Finland and a young sub-population of Kuusamo.
European journal of human genetics : EJHG 2000;8(8):604-12.
2000: Jesper Ekelund; Dirk Lichtermann; Iiris Hovatta; Pekka Ellonen; Jaana Suvisaari; Joseph D Terwilliger; Hannu Juvonen; Teppo Varilo; Ritva Arajärvi; ML Kokko-Sahin; Jouko Lönnqvist; Leena Peltonen
Genome-wide scan for schizophrenia in the Finnish population: evidence for a locus on chromosome 7q22.
Human molecular genetics 2000;9(7):1049-57.
1999: Iiris Hovatta; Teppo Varilo; Jaana Suvisaari; Joseph D Terwilliger; Vesa Ollikainen; Ritva Arajärvi; Hannu Juvonen; ML Kokko-Sahin; L Väisänen; Heikki Mannila; Jouko Lönnqvist; Leena Peltonen
A genomewide screen for schizophrenia genes in an isolated Finnish subpopulation, suggesting multiple susceptibility loci.
American journal of human genetics 1999;65(4):1114-24.
1999: Ilona Visapää; Riitta Salonen; Teppo Varilo; P Paavola; Leena Peltonen
Assignment of the locus for hydrolethalus syndrome to a highly restricted region on 11q23-25.
American journal of human genetics 1999;65(4):1086-95.
1999: Leena Peltonen; Anu Jalanko; Teppo Varilo
Molecular genetics of the Finnish disease heritage.
Human molecular genetics 1999;8(10):1913-23.
1998: P Pekkarinen; Marjo Kestilä; Juha Paloneva; J Terwillign; Teppo Varilo; O Järvi; Panu Hakola; Leena Peltonen
Fine-scale mapping of a novel dementia gene, PLOSL, by linkage disequilibrium.
Genomics 1998;54(2):307-15.
1998: Ilona Visapää; Vineta Fellman; Teppo Varilo; Aarno Palotie; Kari O Raivio; Leena Peltonen
Assignment of the locus for a new lethal neonatal metabolic syndrome to 2q33-37.
American journal of human genetics 1998;63(5):1396-403.
1998: Irma Järvelä; Nabil Sabri Enattah; J Kokkonen; Teppo Varilo; Erkki Savilahti; Leena Peltonen
Assignment of the locus for congenital lactase deficiency to 2q21, in the vicinity of but separate from the lactase-phlorizin hydrolase gene.
American journal of human genetics 1998;63(4):1078-85.
1998: Vineta Fellman; Juhani Rapola; Helena Pihko; Teppo Varilo; Kari O Raivio
Iron-overload disease in infants involving fetal growth retardation, lactic acidosis, liver haemosiderosis, and aminoaciduria.
Lancet 1998;351(9101):490-3.
1996: Teppo Varilo; Kaisu Nikali; Anu Suomalainen; Tuula Lönnqvist; Leena Peltonen
Tracing an ancestral mutation: genealogical and haplotype analysis of the infantile onset spinocerebellar ataxia locus.
Genome research 1996;6(9):870-5.
1996: Teppo Varilo; M Savukoski; R Norio; Pirkko Santavuori; Leena Peltonen; Irma Järvelä
The age of human mutation: genealogical and linkage disequilibrium analysis of the CLN5 mutation in the Finnish population.
American journal of human genetics 1996;58(3):506-12.