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Toine Bovee

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Si Wang; Jac M M J G Aarts; Ad Peijnenburg; Marieke J Pen; Ivonne M C M Rietjens; Jeroen C W Rijk; Toine F H Bovee
A low-density DNA microchip for the detection of (anti-)estrogenic compounds and their relative potencies.
Jac M M J G Aarts; René Houtman; Ivonne M C M Rietjens; Rinie M G J van Beuningen; Beppy J Van De Waart; Si Wang; Walter M A Westerink; Toine F H Bovee
Robust array-based coregulator binding assay predicting ERα-agonist potency and generating binding profiles reflecting ligand structure.
Marit Reitsma; Toine F H Bovee; Peter J M Hendriksen; Ron L A P Hoogenboom; Ad Peijnenburg; Jeroen C W Rijk
Endocrine-disrupting effects of thioxanthone photoinitiators.

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All Publications

2013: Si Wang; Jac M M J G Aarts; Ad Peijnenburg; Marieke J Pen; Ivonne M C M Rietjens; Jeroen C W Rijk; Toine F H Bovee
A low-density DNA microchip for the detection of (anti-)estrogenic compounds and their relative potencies.
Analytical biochemistry 2013;435(1):83-92.
2013: Jac M M J G Aarts; René Houtman; Ivonne M C M Rietjens; Rinie M G J van Beuningen; Beppy J Van De Waart; Si Wang; Walter M A Westerink; Toine F H Bovee
Robust array-based coregulator binding assay predicting ERα-agonist potency and generating binding profiles reflecting ligand structure.
Chemical research in toxicology 2013;26(3):336-46.
2013: Marit Reitsma; Toine F H Bovee; Peter J M Hendriksen; Ron L A P Hoogenboom; Ad Peijnenburg; Jeroen C W Rijk
Endocrine-disrupting effects of thioxanthone photoinitiators.
Toxicological sciences : an official journal of the Society of Toxicology 2013;132(1):64-74.
2013: Si Wang; Jac Aarts; René Houtman; Diana Melchers; Ad Peijnenburg; Ivonne Rietjens; Rinie van Beuningen; Toine F H Bovee
A 155-plex high-throughput in vitro coregulator binding assay for (anti-)estrogenicity testing evaluated with 23 reference compounds.
ALTEX 2013;30(2):145-57.
2013: Toine F H Bovee; Bram A Brouwer; Astrid R M Hamers; Richard J R Helsdingen; Henri H Heskamp; Michel W F Nielen
Validation of a recombinant cell bioassay for the detection of (gluco)corticosteroids in feed.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 2013;30(2):264-71.
2012: Jeroen C W Rijk; Toine F H Bovee; Maria J Groot; Ad Peijnenburg; Ivonne M C M Rietjens; Michel W F Nielen
Bovine liver slices: A multifunctional in vitro model to study the prohormone dehydroepiandrosterone (DHEA).
Toxicology in vitro : an international journal published in association with BIBRA 2012;26(6):1014-21.
2012: Jeroen C W Rijk; MH Blokland; Ron L A P Hoogenboom; Arjen Lommen; Ad Peijnenburg; Toine F H Bovee
Screening for modulatory effects on steroidogenesis using the human H295R adrenocortical cell line: a metabolomics approach.
Chemical research in toxicology 2012;25(8):1720-31.
2012: Rudy Simons; Marian A Verbruggen; Toine F H Bovee; Harry Gruppen; Jean-Paul Vincken
Prenylated isoflavonoids from plants as selective estrogen receptor modulators (phytoSERMs).
Food & function 2012;3(8):810-27.
2011: Mai Thao Nguyen; Ron van der Oost; Toine F H Bovee
Validation of the REA bioassay to detect estrogenic activity in the water cycle.
Toxicology in vitro : an international journal published in association with BIBRA 2011;25(8):2003-9.
2011: Toine F H Bovee; Christopher T Elliott; P J M Hendriksen; M W F Nielen; Ad Peijnenburg; L Portier; Hans P van Egmond; S Wang; L A P Hoogenboom
Tailored microarray platform for the detection of marine toxins.
Environmental science & technology 2011;45(20):8965-73.
2011: Elsa C Antunes-Fernandes; Toine F H Bovee; Frieda E J Daamen; Richard J Helsdingen; Martin van den Berg; Majorie B M van Duursen
Some OH-PCBs are more potent inhibitors of aromatase activity and (anti-) glucocorticoids than non-dioxin like (NDL)-PCBs and MeSO₂-PCBs.
Toxicology letters 2011;206(2):158-65.
2011: Jeroen C W Rijk; Sandra J A van Kuijk; Helen Ashwin; Toine F H Bovee; Maria J Groot; Henri H Heskamp; Michel W F Nielen
Bioassay based screening of steroid derivatives in animal feed and supplements.
Analytica chimica acta 2011;700(1-2):183-8.
2011: Monika Plotan; Marie-Louise SCIPPO; Jean-Philippe Antignac; Toine F H Bovee; Christopher T Elliott; Edward Malone; Samuel Mitchell; Marc Muller; Lisa Connolly
The application of reporter gene assays for the detection of endocrine disruptors in sport supplements.
Analytica chimica acta 2011;700(1-2):34-40.
2011: Toine F H Bovee; Bram A Brouwer; Astrid R M Hamers; Richard J R Helsdingen; Michel W F Nielen
Recombinant cell bioassays for the detection of (gluco)corticosteroids and endocrine-disrupting potencies of several environmental PCB contaminants.
Analytical and bioanalytical chemistry 2011;401(3):873-82.
2011: Rudy Simons; Susan A M The; Marian A Verbruggen; Jean-Paul Vincken; Toine F H Bovee; Teus J C Luijendijk; Loes A M Mol; Harry Gruppen
Agonistic and antagonistic estrogens in licorice root (Glycyrrhiza glabra).
Analytical and bioanalytical chemistry 2011;401(1):305-13.
2011: Rudy Simons; Martijn van Iersel; Marian A Verbruggen; Jean-Paul Vincken; Toine F H Bovee; Nikolaos Roidos; Harry Gruppen
Increasing soy isoflavonoid content and diversity by simultaneous malting and challenging by a fungus to modulate estrogenicity.
Journal of agricultural and food chemistry 2011;59(12):6748-58.
2011: Ilse Becue; Toine F H Bovee; Christof Van Poucke; Maria J Groot; Michel W F Nielen; Carlos Van Peteghem
Applicability of a yeast bioassay in the detection of steroid esters in hair.
Analytical and bioanalytical chemistry 2011;399(3):1031-9.
2010: A M Sotoca; Toine F H Bovee; W Brand; Nadya Velikova; Sjef Boeren; Albertinka J Murk; J Vervoort; I M C M Rietjens
Superinduction of estrogen receptor mediated gene expression in luciferase based reporter gene assays is mediated by a post-transcriptional mechanism.
The Journal of steroid biochemistry and molecular biology 2010;122(4):204-11.
2010: S Wang; J C W Rijk; J H Riethoff-Poortman; S Van Kuijk; Ad Peijnenburg; Toine F H Bovee
Bovine liver slices combined with an androgen transcriptional activation assay: an in-vitro model to study the metabolism and bioactivity of steroids.
Analytical and bioanalytical chemistry 2010;397(2):631-41.
2010: R J B Peters; J C W Rijk; Toine F H Bovee; A W J M Nijrolder; Arjen Lommen; Michel W F Nielen
Identification of anabolic steroids and derivatives using bioassay-guided fractionation, UHPLC/TOFMS analysis and accurate mass database searching.
Analytica chimica acta 2010;664(1):77-88.
2010: Ilse Becue; Christof Van Poucke; Jeroen C W Rijk; Toine F H Bovee; Michel W F Nielen; Carlos Van Peteghem
Investigation of urinary steroid metabolites in calf urine after oral and intramuscular administration of DHEA.
Analytical and bioanalytical chemistry 2010;396(2):799-808.
2010: Toine F H Bovee; Mario Thevis; Astrid R M Hamers; Ad Peijnenburg; Michel W F Nielen; Willem G E J Schoonen
SERMs and SARMs: detection of their activities with yeast based bioassays.
The Journal of steroid biochemistry and molecular biology 2010;118(1-2):85-92.
2009: Jeroen C W Rijk; Toine F H Bovee; Si Wang; Christof Van Poucke; Carlos Van Peteghem; Michel W F Nielen
Detection of anabolic steroids in dietary supplements: the added value of an androgen yeast bioassay in parallel with a liquid chromatography-tandem mass spectrometry screening method.
Analytica chimica acta 2009;637(1-2):305-14.
2009: Toine F H Bovee; Gerrit Bor; Ilse Becue; Frieda E J Daamen; Majorie B M van Duursen; Sylvi Lehmann; Günter Vollmer; Raffaella De Maria; Jennifer E Fox; Hilda Witters; Silke Bernhöft; Karl-Werner Schramm; Ron L A P Hoogenboom; Michel W F Nielen
Inter-laboratory comparison of a yeast bioassay for the determination of estrogenic activity in biological samples.
Analytica chimica acta 2009;637(1-2):265-72.
2009: Toine F H Bovee; Gerrit Bor; Henri H Heskamp; Johan J P Lasaroms; Marieke B Sanders; Michel W F Nielen
Validation and application of a yeast bioassay for screening androgenic activity in calf urine and feed.
Analytica chimica acta 2009;637(1-2):225-34.
2008: Toine F H Bovee; Willem G E J Schoonen; Astrid R M Hamers; Marta Jorge Bento; Ad Peijnenburg
Screening of synthetic and plant-derived compounds for (anti)estrogenic and (anti)androgenic activities.
Analytical and bioanalytical chemistry 2008;390(4):1111-9.
2008: Toine F H Bovee; Jos Lommerse; Ad Peijnenburg; Elsa Antunes Fernandes; Michel W F Nielen
A new highly androgen specific yeast biosensor, enabling optimisation of (Q)SAR model approaches.
The Journal of steroid biochemistry and molecular biology 2008;108(1-2):121-31.
2007: Toine F H Bovee; Richard J R Helsdingen; Astrid R M Hamers; Majorie B M van Duursen; Michel W F Nielen; Ron L A P Hoogenboom
A new highly specific and robust yeast androgen bioassay for the detection of agonists and antagonists.
Analytical and bioanalytical chemistry 2007;389(5):1549-58.
2007: Jennifer E Fox; Jamie T Bridgham; Toine F H Bovee; Joseph W Thornton
An evolvable oestrogen receptor activity sensor: development of a modular system for integrating multiple genes into the yeast genome.
Yeast (Chichester, England) 2007;24(5):379-90.
2007: Michel W F Nielen; Johan J P Lasaroms; Martien L Essers; Marieke B Sanders; Henri H Heskamp; Toine F H Bovee; J Hans A van Rhijn; Maria J Groot
The ultimate veal calf reference experiment: hormone residue analysis data obtained by gas and liquid chromatography tandem mass spectrometry.
Analytica chimica acta 2007;586(1-2):30-4.
2006: Michel W F Nielen; Toine F H Bovee; Henri H Heskamp; Johan J P Lasaroms; M B Sanders; Johannes A van Rhijn; Maria J Groot; L A P Hoogenboom
Screening for estrogen residues in calf urine: comparison of a validated yeast estrogen bioassay and gas chromatography-tandem mass spectrometry.
Food additives and contaminants 2006;23(11):1123-31.
2006: Toine F H Bovee; Gerrit Bor; Henri H Heskamp; Ron L A P Hoogenboom; Michel W F Nielen
Validation and application of a robust yeast estrogen bioassay for the screening of estrogenic activity in animal feed.
Food additives and contaminants 2006;23(6):556-68.
2006: Michel W F Nielen; Toine F H Bovee; Marcel C van Engelen; Paula Rutgers; Astrid R M Hamers; J Hans A van Rhijn; L Ron A P Hoogenboom
Urine testing for designer steroids by liquid chromatography with androgen bioassay detection and electrospray quadrupole time-of-flight mass spectrometry identification.
Analytical chemistry 2006;78(2):424-31.
2004: Michel W F Nielen; Eric O van Bennekom; Henri H Heskamp; J Hans A van Rhijn; Toine F H Bovee; L Ron A P Hoogenboom
Bioassay-directed identification of estrogen residues in urine by liquid chromatography electrospray quadrupole time-of-flight mass spectrometry.
Analytical chemistry 2004;76(22):6600-8.
2004: L A P Hoogenboom; CA Kan; Toine F H Bovee; G van der Weg; C Onstenk; Win Traag
Residues of dioxins and PCBs in fat of growing pigs and broilers fed contaminated feed.
Chemosphere 2004;57(1):35-42.
2004: Ron Hoogenboom; Toine F H Bovee; Liza Portier; Gerrit Bor; G van der Weg; Constant Onstenk; Win Traag
The German bakery waste incident; use of a combined approach of screening and confirmation for dioxins in feed and food.
Talanta 2004;63(5):1249-53.
2004: Toine F H Bovee; Richard J R Helsdingen; Ivonne M C M Rietjens; Jaap Keijer; Ron L A P Hoogenboom
Rapid yeast estrogen bioassays stably expressing human estrogen receptors alpha and beta, and green fluorescent protein: a comparison of different compounds with both receptor types.
The Journal of steroid biochemistry and molecular biology 2004;91(3):99-109.
2004: Toine F H Bovee; Richard J R Helsdingen; Patrick D Koks; Harry A Kuiper; Ron L A P Hoogenboom; Jaap Keijer
Development of a rapid yeast estrogen bioassay, based on the expression of green fluorescent protein.
Gene 2004;325():187-200.
1999: L A P Hoogenboom; Astrid R M Hamers; Toine F H Bovee
Bioassays for the detection of growth-promoting agents, veterinary drugs and environmental contaminants in food.
The Analyst 1999;124(1):79-85.
1998: Toine F H Bovee; L A P Hoogenboom; Astrid R M Hamers; Win Traag; T Zuidema; J M Aarts; Abraham Brouwer; Harry A Kuiper
Validation and use of the CALUX-bioassay for the determination of dioxins and PCBs in bovine milk.
Food additives and contaminants 1998;15(8):863-75.