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Adriana Vasil

Research Profile

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Pseudomonas aeruginosa

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Chemicals & Drugs

Physiology

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Publications

TOP 3
Ziqing Jiang; Adriana I Vasil; Lajos Gera; Michael L Vasil; Robert S Hodges
Rational design of α-helical antimicrobial peptides to target Gram-negative pathogens, Acinetobacter baumannii and Pseudomonas aeruginosa: utilization of charge, 'specificity determinants,' total hydrophobicity, hydrophobe type and location as design parameters to improve the therapeutic ratio.
Michael Vasil; Martin J Stonehouse; Adriana I Vasil; Sandra J Wadsworth; Howard Goldfine; Robert E Bolcome; Joanne Chan
A complex extracellular sphingomyelinase of Pseudomonas aeruginosa inhibits angiogenesis by selective cytotoxicity to endothelial cells.
Ziqing Jiang; Adriana I Vasil; John Hale; Robert E W Hancock; Michael L Vasil; Robert S Hodges
Effects of net charge and the number of positively charged residues on the biological activity of amphipathic alpha-helical cationic antimicrobial peptides.

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All Publications

2011: Ziqing Jiang; Adriana I Vasil; Lajos Gera; Michael L Vasil; Robert S Hodges
Rational design of α-helical antimicrobial peptides to target Gram-negative pathogens, Acinetobacter baumannii and Pseudomonas aeruginosa: utilization of charge, 'specificity determinants,' total hydrophobicity, hydrophobe type and location as design parameters to improve the therapeutic ratio.
Chemical biology & drug design 2011;77(4):225-40.
2009: Michael Vasil; Martin J Stonehouse; Adriana I Vasil; Sandra J Wadsworth; Howard Goldfine; Robert E Bolcome; Joanne Chan
A complex extracellular sphingomyelinase of Pseudomonas aeruginosa inhibits angiogenesis by selective cytotoxicity to endothelial cells.
PLoS pathogens 2009;5(5):e1000420.
2009: Ziqing Jiang; Adriana I Vasil; John Hale; Robert E W Hancock; Michael L Vasil; Robert S Hodges
Effects of net charge and the number of positively charged residues on the biological activity of amphipathic alpha-helical cationic antimicrobial peptides.
Advances in experimental medicine and biology 2009;611():561-2.
2008: Rhea M Miller; Andrew P Tomaras; Adam P Barker; Dennis R Voelker; Edward D Chan; Adriana I Vasil; Michael Vasil
Pseudomonas aeruginosa twitching motility-mediated chemotaxis towards phospholipids and fatty acids: specificity and metabolic requirements.
Journal of bacteriology 2008;190(11):4038-49.
2008: Ziqing Jiang; Adriana I Vasil; John D Hale; Robert E W Hancock; Michael Vasil; Robert S Hodges
Effects of net charge and the number of positively charged residues on the biological activity of amphipathic alpha-helical cationic antimicrobial peptides.
Biopolymers 2008;90(3):369-83.
2007: Yuxin Chen; Michael T Guarnieri; Adriana I Vasil; Michael Vasil; Colin T Mant; Robert S Hodges
Role of peptide hydrophobicity in the mechanism of action of alpha-helical antimicrobial peptides.
Antimicrobial agents and chemotherapy 2007;51(4):1398-406.
2006: Aleksandra Snyder; Adriana I Vasil; Sheryl L Zajdowicz; Zachary R Wilson; Michael Vasil
Role of the Pseudomonas aeruginosa PlcH Tat signal peptide in protein secretion, transcription, and cross-species Tat secretion system compatibility.
Journal of bacteriology 2006;188(5):1762-74.
2006: Yuxin Chen; Adriana I Vasil; Linda Rehaume; Colin T Mant; Jane L Burns; Michael Vasil; Robert E W Hancock; Robert S Hodges
Comparison of biophysical and biologic properties of alpha-helical enantiomeric antimicrobial peptides.
Chemical biology & drug design 2006;67(2):162-73.
2004: Adam P Barker; Adriana I Vasil; Alain Filloux; Geneviève Ball; Paula J Wilderman; Michael Vasil
A novel extracellular phospholipase C of Pseudomonas aeruginosa is required for phospholipid chemotaxis.
Molecular microbiology 2004;53(4):1089-98.
2003: Chiara Luberto; Martin J Stonehouse; Elizabeth A Collins; Norma Marchesini; Samer El Bawab; Adriana I Vasil; Michael Vasil; Yusuf A Hannun
Purification, characterization, and identification of a sphingomyelin synthase from Pseudomonas aeruginosa. PlcH is a multifunctional enzyme.
The Journal of biological chemistry 2003;278(35):32733-43.
2002: Martin J Stonehouse; Adela Cota-Gomez; Sarah K Parker; Wesley E Martin; Joseph A Hankin; Robert C Murphy; Weibin Chen; Kheng B Lim; Murray Hackett; Adriana I Vasil; Michael Vasil
A novel class of microbial phosphocholine-specific phospholipases C.
Molecular microbiology 2002;46(3):661-76.
2002: Urs A Ochsner; Paula J Wilderman; Adriana I Vasil; Michael Vasil
GeneChip expression analysis of the iron starvation response in Pseudomonas aeruginosa: identification of novel pyoverdine biosynthesis genes.
Molecular microbiology 2002;45(5):1277-87.
2002: Paula J Wilderman; Adriana I Vasil; Wesley E Martin; Robert C Murphy; Michael Vasil
Pseudomonas aeruginosa synthesizes phosphatidylcholine by use of the phosphatidylcholine synthase pathway.
Journal of bacteriology 2002;184(17):4792-9.
2002: Urs A Ochsner; Aleksandra Snyder; Adriana I Vasil; Michael Vasil
Effects of the twin-arginine translocase on secretion of virulence factors, stress response, and pathogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):8312-7.
2002: Iain L Lamont; Paul A Beare; Urs A Ochsner; Adriana I Vasil; Michael Vasil
Siderophore-mediated signaling regulates virulence factor production in Pseudomonasaeruginosa.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):7072-7.
2001: Paula J Wilderman; Adriana I Vasil; Z Johnson; Megan J Wilson; Heather Cunliffe; Iain L Lamont; Michael Vasil
Characterization of an endoprotease (PrpL) encoded by a PvdS-regulated gene in Pseudomonas aeruginosa.
Infection and immunity 2001;69(9):5385-94.
2001: Paula J Wilderman; Adriana I Vasil; Z Johnson; Michael Vasil
Genetic and biochemical analyses of a eukaryotic-like phospholipase D of Pseudomonas aeruginosa suggest horizontal acquisition and a role for persistence in a chronic pulmonary infection model.
Molecular microbiology 2001;39(2):291-303.
1999: LS Terada; K A Johansen; Sogol Nowbar; Adriana I Vasil; Michael Vasil
Pseudomonas aeruginosa hemolytic phospholipase C suppresses neutrophil respiratory burst activity.
Infection and immunity 1999;67(5):2371-6.
1999: Urs A Ochsner; Adriana I Vasil; Z Johnson; Michael Vasil
Pseudomonas aeruginosa fur overlaps with a gene encoding a novel outer membrane lipoprotein, OmlA.
Journal of bacteriology 1999;181(4):1099-109.
1997: Adela Cota-Gomez; Adriana I Vasil; JL Kadurugamuwa; Terry J Beveridge; H P Schweizer; Michael Vasil
PlcR1 and PlcR2 are putative calcium-binding proteins required for secretion of the hemolytic phospholipase C of Pseudomonas aeruginosa.
Infection and immunity 1997;65(7):2904-13.
1997: A E Sage; Adriana I Vasil; Michael Vasil
Molecular characterization of mutants affected in the osmoprotectant-dependent induction of phospholipase C in Pseudomonas aeruginosa PAO1.
Molecular microbiology 1997;23(1):43-56.
1996: H A Barton; Z Johnson; C D Cox; Adriana I Vasil; Michael Vasil
Ferric uptake regulator mutants of Pseudomonas aeruginosa with distinct alterations in the iron-dependent repression of exotoxin A and siderophores in aerobic and microaerobic environments.
Molecular microbiology 1996;21(5):1001-17.
1995: Urs A Ochsner; Adriana I Vasil; Michael Vasil
Role of the ferric uptake regulator of Pseudomonas aeruginosa in the regulation of siderophores and exotoxin A expression: purification and activity on iron-regulated promoters.
Journal of bacteriology 1995;177(24):7194-201.
1991: R W Prince; Douglas G Storey; Adriana I Vasil; Michael Vasil
Regulation of toxA and regA by the Escherichia coli fur gene and identification of a Fur homologue in Pseudomonas aeruginosa PA103 and PA01.
Molecular microbiology 1991;5(11):2823-31.
1991: V D Shortridge; Martin Pato; Adriana I Vasil; Michael Vasil
Physical mapping of virulence-associated genes in Pseudomonas aeruginosa by transverse alternating-field electrophoresis.
Infection and immunity 1991;59(10):3596-603.
1991: Michael Vasil; L M Graham; R M Ostroff; V D Shortridge; Adriana I Vasil
Phospholipase C: molecular biology and contribution to the pathogenesis of Pseudomonas aeruginosa.
Antibiotics and chemotherapy 1991;44():34-47.
1990: Michael Vasil; D P Krieg; J S Kuhns; J W Ogle; V D Shortridge; R M Ostroff; Adriana I Vasil
Molecular analysis of hemolytic and phospholipase C activities of Pseudomonas cepacia.
Infection and immunity 1990;58(12):4020-9.
1990: R M Ostroff; Adriana I Vasil; Michael Vasil
Molecular comparison of a nonhemolytic and a hemolytic phospholipase C from Pseudomonas aeruginosa.
Journal of bacteriology 1990;172(10):5915-23.
1990: L M Graham; Adriana I Vasil; Michael Vasil; Norbert F Voelkel; Kurt R Stenmark
Decreased pulmonary vasoreactivity in an animal model of chronic Pseudomonas pneumonia.
The American review of respiratory disease 1990;142(1):221-9.
1987: Michael Vasil; J W Ogle; C C Grant; Adriana I Vasil
Recombinant DNA approaches to the study of the regulation of virulence factors and epidemiology of Pseudomonas aeruginosa.
Antibiotics and chemotherapy 1987;39():264-78.