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Gilbert Vassart

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Co-Publications
Name
57
Costagliola, Sabine
42
Van Sande, Jacqueline
41
Parma, Jasmine
41
Dumont, Jacques
34
Parmentier, Marc
30
Christophe, Daniel
23
Ludgate, Marian
21
Duprez, Laurence
17
Tonacchera, Massimo
16
Targovnik, Héctor
13
Smits, Guillaume
13
detheux, Michel
13
Blanpain, Cédric
13
Maenhaut, Carine
13
Govaerts, Cédric

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Publications

TOP 3
Vassart Gilbert
Omissions and misquotations: rewriting history.
Garcia Marie Isabelle; Ghiani Mariangela; Lefort Anne; Libert Frédérick; Strollo Sandra; Vassart Gilbert
LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine.
Lambot Marie-Alexandra H; Mendive Fernando; Laurent Patrick; Van Schoore Gregory; Noël Jean-Christophe; Vanderhaeghen Pierre; Vassart Gilbert
Three-dimensional reconstruction of efferent ducts in wild-type and Lgr4 knock-out mice.

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All Publications

2009: Vassart Gilbert
Omissions and misquotations: rewriting history.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2009;15(4):383-4; author reply 384-5.
2009: Garcia Marie Isabelle; Ghiani Mariangela; Lefort Anne; Libert Frédérick; Strollo Sandra; Vassart Gilbert
LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine.
Developmental biology 2009;331(1):58-67.
2009: Lambot Marie-Alexandra H; Mendive Fernando; Laurent Patrick; Van Schoore Gregory; Noël Jean-Christophe; Vanderhaeghen Pierre; Vassart Gilbert
Three-dimensional reconstruction of efferent ducts in wild-type and Lgr4 knock-out mice.
Anatomical record (Hoboken, N.J. : 2007) 2009;292(4):595-603.
2009: Maquet Emilie; Costagliola Sabine; Parma Jasmine; Christophe-Hobertus Christiane; Oligny Luc L; Fournet Jean-Christophe; Robitaille Yves; Vuissoz Jean-Marc; Payot Antoine; Laberge Sophie; Vassart Gilbert; Van Vliet Guy; Deladoëy Johnny
Lethal respiratory failure and mild primary hypothyroidism in a term girl with a de novo heterozygous mutation in the TITF1/NKX2.1 gene.
The Journal of clinical endocrinology and metabolism 2009;94(1):197-203.
2009: van Vliet Guy; Vassart Gilbert
Monozygotic twins are generally discordant for congenital hypothyroidism from thyroid dysgenesis.
Hormone research 2009;72(5):320.
2009: Valverde Olga; Célérier Evelyne; Baranyi Mária; Vanderhaeghen Pierre; Maldonado Rafael; Sperlagh Beata; Vassart Gilbert; Ledent Catherine
GPR3 receptor, a novel actor in the emotional-like responses.
PloS one 2009;4(3):e4704.
2008: Gonzalez-Merino E; Emiliani S; Pichon B; Parma J; Vannin A S; Delbaere A; Vassart G; Abramowicz M; Englert Y
[Preimplantation genetic diagnosis (PGD): the Erasme Hospital experience]
Revue médicale de Bruxelles 2008;29(6):527-34.
2008: Akcurin Sema; Turkkahraman Doga; Tysoe Carolyn; Ellard Sian; De Leener Anne; Vassart Gilbert; Costagliola Sabine
A family with a novel TSH receptor activating germline mutation (p.Ala485Val).
European journal of pediatrics 2008;167(11):1231-7.
2008: Sanjeevaiah Aravind Raj; Vassart Gilbert; Srikanta Sri S
Follicle-stimulating hormone receptor DNA sequencing: investigation into possible glycoprotein receptor mutation in Van Wyk-Grumbach syndrome.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2008;14(5):648.
2008: Decaux Guy; Soupart Alain; Vassart Gilbert
Non-peptide arginine-vasopressin antagonists: the vaptans.
Lancet 2008;371(9624):1624-32.
2008: Deladoëy Johnny; Pfarr Nicole; Vuissoz Jean-Marc; Parma Jasmine; Vassart Gilbert; Biesterfeld Stefan; Pohlenz Joachim; Van Vliet Guy
Pseudodominant inheritance of goitrous congenital hypothyroidism caused by TPO mutations: molecular and in silico studies.
The Journal of clinical endocrinology and metabolism 2008;93(2):627-33.
2008: Bassett J H Duncan; Williams Allan J; Murphy Elaine; Boyde Alan; Howell Peter G T; Swinhoe Rowan; Archanco Marta; Flamant Frédéric; Samarut Jacques; Costagliola Sabine; Vassart Gilbert; Weiss Roy E; Refetoff Samuel; Williams Graham R
A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism.
Molecular endocrinology (Baltimore, Md.) 2008;22(2):501-12.
2008: De Leener Anne; Caltabiano Gianluigi; Erkan Sanly; Idil Mehmet; Vassart Gilbert; Pardo Leonardo; Costagliola Sabine
Identification of the first germline mutation in the extracellular domain of the follitropin receptor responsible for spontaneous ovarian hyperstimulation syndrome.
Human mutation 2008;29(1):91-8.
2008: Van Loy Tom; Vandersmissen Hans Peter; Van Hiel Matthias B; Poels Jeroen; Verlinden Heleen; Badisco Liesbeth; Vassart Gilbert; Vanden Broeck Jozef
Comparative genomics of leucine-rich repeats containing G protein-coupled receptors and their ligands.
General and comparative endocrinology 2008;155(1):14-21.
2007: Mievis Stéphane; Levivier Marc; Vassart Gilbert; Brotchi Jacques; Ledent Catherine; Blum David
Citicoline is not protective in experimental models of Huntington's disease.
Neurobiology of aging 2007;28(12):1944-6.
2007: Springael Jean-Yves; Urizar Eneko; Costagliola Sabine; Vassart Gilbert; Parmentier Marc
Allosteric properties of G protein-coupled receptor oligomers.
Pharmacology & therapeutics 2007;115(3):410-8.
2007: Van Loy Tom; Van Hiel Matthias B; Vandersmissen Hans Peter; Poels Jeroen; Mendive Fernando; Vassart Gilbert; Vanden Broeck Jozef
Evolutionary conservation of bursicon in the animal kingdom.
General and comparative endocrinology 2007;153(1-3):59-63.
2007: Dessars Barbara; De Raeve Linda E; El Housni Hakim; Debouck Catherine J; Sidon Pierre J; Morandini Renato; Roseeuw Diane; Ghanem Ghanem E; Vassart Gilbert; Heimann Pierre
Chromosomal translocations as a mechanism of BRAF activation in two cases of large congenital melanocytic nevi.
The Journal of investigative dermatology 2007;127(6):1468-70.
2007: Decaux Guy; Vandergheynst Frédéric; Bouko Yasmina; Parma Jasmine; Vassart Gilbert; Vilain Catheline
Nephrogenic syndrome of inappropriate antidiuresis in adults: high phenotypic variability in men and women from a large pedigree.
Journal of the American Society of Nephrology : JASN 2007;18(2):606-12.
2007: Deladoëy Johnny; Vassart Gilbert; Van Vliet Guy
Possible non-Mendelian mechanisms of thyroid dysgenesis.
Endocrine development 2007;10():29-42.
2007: Mievis Stéphane; Levivier Marc; Communi David; Vassart Gilbert; Brotchi Jacques; Ledent Catherine; Blum David
Lack of minocycline efficiency in genetic models of Huntington's disease.
Neuromolecular medicine 2007;9(1):47-54.
2006: Bonomi Marco; Busnelli Marta; Persani Luca; Vassart Gilbert; Costagliola Sabine
Structural differences in the hinge region of the glycoprotein hormone receptors: evidence from the sulfated tyrosine residues.
Molecular endocrinology (Baltimore, Md.) 2006;20(12):3351-63.
2006: Delbaere Anne; Smits Guillaume; Vassart Gilbert; Costagliola Sabine
Genetic predictors of ovarian hyperstimulation syndrome in women undergoing in vitro fertilization.
Nature clinical practice. Endocrinology & metabolism 2006;2(11):590-1.
2006: Van Durme Joost; Horn Florence; Costagliola Sabine; Vriend Gert; Vassart Gilbert
GRIS: glycoprotein-hormone receptor information system.
Molecular endocrinology (Baltimore, Md.) 2006;20(9):2247-55.
2006: Springael Jean-Yves; Le Minh Phu Nguyen; Urizar Eneko; Costagliola Sabine; Vassart Gilbert; Parmentier Marc
Allosteric modulation of binding properties between units of chemokine receptor homo- and hetero-oligomers.
Molecular pharmacology 2006;69(5):1652-61.
2006: Mendive Fernando; Laurent Patrick; Van Schoore Grégory; Skarnes William; Pochet Roland; Vassart Gilbert
Defective postnatal development of the male reproductive tract in LGR4 knockout mice.
Developmental biology 2006;290(2):421-34.
2006: De Leener A; Montanelli L; Van Durme J; Chae Heedong; Smits G; Vassart G; Costagliola S
Presence and absence of follicle-stimulating hormone receptor mutations provide some insights into spontaneous ovarian hyperstimulation syndrome physiopathology.
The Journal of clinical endocrinology and metabolism 2006;91(2):555-62.
2005: Laurent Patrick; Becker Jerome A J; Valverde Olga; Ledent Catherine; de Kerchove d'Exaerde Alban; Schiffmann Serge N; Maldonado Rafael; Vassart Gilbert; Parmentier Marc
The prolactin-releasing peptide antagonizes the opioid system through its receptor GPR10.
Nature neuroscience 2005;8(12):1735-41.
2005: Vassart Gilbert; Dumont Jacques E
Thyroid dysgenesis: multigenic or epigenetic ... or both?
Endocrinology 2005;146(12):5035-7.
2005: Grasberger Helmut; Vaxillaire Martine; Pannain Silvana; Beck John C; Mimouni-Bloch Aviva; Vatin Vincent; Vassart Gilbert; Froguel Philippe; Refetoff Samuel
Identification of a locus for nongoitrous congenital hypothyroidism on chromosome 15q25.3-26.1.
Human genetics 2005;118(3-4):348-55.
2005: Costagliola Sabine; Urizar Eneko; Mendive Fernando; Vassart Gilbert
Specificity and promiscuity of gonadotropin receptors.
Reproduction (Cambridge, England) 2005;130(3):275-81.
2005: Van Schoore Grégory; Mendive Fernando; Pochet Roland; Vassart Gilbert
Expression pattern of the orphan receptor LGR4/GPR48 gene in the mouse.
Histochemistry and cell biology 2005;124(1):35-50.
2005: Vassart Gilbert; Vanden Broeck Jozef; Mendive Fernando; Van Loy Tom
The parable of the mandarin.
EMBO reports 2005;6(7):592.
2005: Wittamer Valérie; Bondue Benjamin; Guillabert Aude; Vassart Gilbert; Parmentier Marc; Communi David
Neutrophil-mediated maturation of chemerin: a link between innate and adaptive immunity.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(1):487-93.
2005: Grasberger Helmut; Mimouni-Bloch Aviva; Vantyghem Marie-Christine; van Vliet Guy; Abramowicz Marc; Metzger Daniel L; Abdullatif Hussein; Rydlewski Catherine; Macchia Paolo E; Scherberg Neal H; van Sande Jacqueline; Mimouni Marc; Weiss Roy E; Vassart Gilbert; Refetoff Samuel
Autosomal dominant resistance to thyrotropin as a distinct entity in five multigenerational kindreds: clinical characterization and exclusion of candidate loci.
The Journal of clinical endocrinology and metabolism 2005;90(7):4025-34.
2005: Grasberger Helmut; Ringkananont Usanee; Lefrancois Paule; Abramowicz Marc; Vassart Gilbert; Refetoff Samuel
Thyroid transcription factor 1 rescues PAX8/p300 synergism impaired by a natural PAX8 paired domain mutation with dominant negative activity.
Molecular endocrinology (Baltimore, Md.) 2005;19(7):1779-91.
2005: Ledent Catherine; Demeestere Isabelle; Blum David; Petermans Julien; Hämäläinen Tuula; Smits Guillaume; Vassart Gilbert
Premature ovarian aging in mice deficient for Gpr3.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(25):8922-6.
2005: Urizar Eneko; Montanelli Lucia; Loy Tiffany; Bonomi Marco; Swillens Stéphane; Gales Céline; Bouvier Michel; Smits Guillaume; Vassart Gilbert; Costagliola Sabine
Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity.
The EMBO journal 2005;24(11):1954-64.
2005: Lagane Bernard; Ballet Sébastien; Planchenault Thierry; Balabanian Karl; Le Poul Emmanuel; Blanpain Cédric; Percherancier Yann; Staropoli Isabelle; Vassart Gilbert; Oppermann Martin; Parmentier Marc; Bachelerie Françoise
Mutation of the DRY motif reveals different structural requirements for the CC chemokine receptor 5-mediated signaling and receptor endocytosis.
Molecular pharmacology 2005;67(6):1966-76.
2005: Delbaere Anne; Smits Guillaume; De Leener Anne; Costagliola Sabine; Vassart Gilbert
Understanding ovarian hyperstimulation syndrome.
Endocrine 2005;26(3):285-90.
2005: Mendive Fernando M; Van Loy Tom; Claeysen Sylvie; Poels Jeroen; Williamson Michael; Hauser Frank; Grimmelikhuijzen Cornelis J P; Vassart Gilbert; Vanden Broeck Jozef
Drosophila molting neurohormone bursicon is a heterodimer and the natural agonist of the orphan receptor DLGR2.
FEBS letters 2005;579(10):2171-6.
2005: Urizar Eneko; Claeysen Sylvie; Deupí Xavier; Govaerts Cedric; Costagliola Sabine; Vassart Gilbert; Pardo Leonardo
An activation switch in the rhodopsin family of G protein-coupled receptors: the thyrotropin receptor.
The Journal of biological chemistry 2005;280(17):17135-41.
2005: El-Asmar Laïla; Springael Jean-Yves; Ballet Sébastien; Andrieu Eneko Urizar; Vassart Gilbert; Parmentier Marc
Evidence for negative binding cooperativity within CCR5-CCR2b heterodimers.
Molecular pharmacology 2005;67(2):460-9.
2005: Migeotte Isabelle; Riboldi Elena; Franssen Jean-Denis; Grégoire Françoise; Loison Cécile; Wittamer Valérie; Detheux Michel; Robberecht Patrick; Costagliola Sabine; Vassart Gilbert; Sozzani Silvano; Parmentier Marc; Communi David
Identification and characterization of an endogenous chemotactic ligand specific for FPRL2.
The Journal of experimental medicine 2005;201(1):83-93.
2005: Becker Jérôme A J; Mirjolet Jean-François; Bernard Jérôme; Burgeon Emmanuel; Simons Marie-Jeanne; Vassart Gilbert; Parmentier Marc; Libert Frédérick
Activation of GPR54 promotes cell cycle arrest and apoptosis of human tumor cells through a specific transcriptional program not shared by other Gq-coupled receptors.
Biochemical and biophysical research communications 2005;326(3):677-86.
2004: Daelemans Caroline; Smits Guillaume; de Maertelaer Viviane; Costagliola Sabine; Englert Yvon; Vassart Gilbert; Delbaere Anne
Prediction of severity of symptoms in iatrogenic ovarian hyperstimulation syndrome by follicle-stimulating hormone receptor Ser680Asn polymorphism.
The Journal of clinical endocrinology and metabolism 2004;89(12):6310-5.
2004: Costagliola Sabine; Bonomi Marco; Morgenthaler Nils G; Van Durme Joost; Panneels Valérie; Refetoff Samuel; Vassart Gilbert
Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity.
Molecular endocrinology (Baltimore, Md.) 2004;18(12):3020-34.
2004: Meeus Laurent; Gilbert Brigitte; Rydlewski Catherine; Parma Jasmine; Roussie Anne Lienhardt; Abramowicz Marc; Vilain Catheline; Christophe Daniel; Costagliola Sabine; Vassart Gilbert
Characterization of a novel loss of function mutation of PAX8 in a familial case of congenital hypothyroidism with in-place, normal-sized thyroid.
The Journal of clinical endocrinology and metabolism 2004;89(9):4285-91.
2004: Montanelli Lucia; Van Durme Joost J J; Smits Guillaume; Bonomi Marco; Rodien Patrice; Devor Eric J; Moffat-Wilson Kristin; Pardo Leonardo; Vassart Gilbert; Costagliola Sabine
Modulation of ligand selectivity associated with activation of the transmembrane region of the human follitropin receptor.
Molecular endocrinology (Baltimore, Md.) 2004;18(8):2061-73.
2004: Poels Jeroen; Van Loy Tom; Franssens Vanessa; Detheux Michel; Nachman Ronald J; Oonk Hendrica B; Akerman Karl E; Vassart Gilbert; Parmentier Marc; De Loof Arnold; Torfs Herbert; Broeck Jozef Vanden
Substitution of conserved glycine residue by alanine in natural and synthetic neuropeptide ligands causes partial agonism at the stomoxytachykinin receptor.
Journal of neurochemistry 2004;90(2):472-8.
2004: Montanelli Lucia; Delbaere Anne; Di Carlo Costantino; Nappi Carmine; Smits Guillaume; Vassart Gilbert; Costagliola Sabine
A mutation in the follicle-stimulating hormone receptor as a cause of familial spontaneous ovarian hyperstimulation syndrome.
The Journal of clinical endocrinology and metabolism 2004;89(4):1255-8.
2004: Vassart Gilbert; Pardo Leonardo; Costagliola Sabine
A molecular dissection of the glycoprotein hormone receptors.
Trends in biochemical sciences 2004;29(3):119-26.
2004: Montanelli Lucia; Delbaere Anne; Di Carlo Costantino; Nappi Carmine; Smits Guillaume; Vassart Gilbert; Costagliola Sabine
A mutation in the follicle-stimulating hormone receptor as a cause of familial spontaneous ovarian hyperstimulation syndrome.
The Journal of clinical endocrinology and metabolism 2004;89(3):1255-8.
2004: Delbaere A; Smits G; Olatunbosun O; Pierson R; Vassart G; Costagliola S
New insights into the pathophysiology of ovarian hyperstimulation syndrome. What makes the difference between spontaneous and iatrogenic syndrome?
Human reproduction (Oxford, England) 2004;19(3):486-9.
2004: Wittamer Valérie; Grégoire Françoise; Robberecht Patrick; Vassart Gilbert; Communi David; Parmentier Marc
The C-terminal nonapeptide of mature chemerin activates the chemerin receptor with low nanomolar potency.
The Journal of biological chemistry 2004;279(11):9956-62.
2004: Vassart Gilbert
Activating mutations of the TSH receptor.
Thyroid : official journal of the American Thyroid Association 2004;14(1):86-7.
2004: Vassart Gilbert; Costagliola Sabine
A physiological role for the posttranslational cleavage of the thyrotropin receptor?
Endocrinology 2004;145(1):1-3.
2004: Vilain Catheline; Vassart Gilbert
Small amplified RNA-SAGE.
Methods in molecular biology (Clifton, N.J.) 2004;258():135-52.
2003: Blanpain Cédric; Le Poul Emmanuel; Parma Jasmine; Knoop Christiane; Detheux Michel; Parmentier Marc; Vassart Gilbert; Abramowicz Marc J
Serotonin 5-HT(2B) receptor loss of function mutation in a patient with fenfluramine-associated primary pulmonary hypertension.
Cardiovascular research 2003;60(3):518-28.
2003: Wittamer Valérie; Franssen Jean-Denis; Vulcano Marisa; Mirjolet Jean-François; Le Poul Emmanuel; Migeotte Isabelle; Brézillon Stéphane; Tyldesley Richard; Blanpain Cédric; Detheux Michel; Mantovani Alberto; Sozzani Silvano; Vassart Gilbert; Parmentier Marc; Communi David
Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids.
The Journal of experimental medicine 2003;198(7):977-85.
2003: El Housni Hakim; Heimann Pierre; Parma Jasmine; Vassart Gilbert
Single-nucleotide polymorphism genotyping by melting analysis of dual-labeled probes: examples using factor V Leiden and prothrombin 20210A mutations.
Clinical chemistry 2003;49(10):1669-72.
2003: Smits Guillaume; Olatunbosun Olufemi; Delbaere Anne; Pierson Roger; Vassart Gilbert; Costagliola Sabine
Ovarian hyperstimulation syndrome due to a mutation in the follicle-stimulating hormone receptor.
The New England journal of medicine 2003;349(8):760-6.
2003: Le Poul Emmanuel; Loison Cecile; Struyf Sofie; Springael Jean-Yves; Lannoy Vincent; Decobecq Marie-Eve; Brezillon Stephane; Dupriez Vincent; Vassart Gilbert; Van Damme Jo; Parmentier Marc; Detheux Michel
Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation.
The Journal of biological chemistry 2003;278(28):25481-9.
2003: Smits Guillaume; Campillo Mercedes; Govaerts Cédric; Janssens Véronique; Richter Christine; Vassart Gilbert; Pardo Leonardo; Costagliola Sabine
Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificity.
The EMBO journal 2003;22(11):2692-703.
2003: Vilain Catheline; Libert Frederick; Venet David; Costagliola Sabine; Vassart Gilbert
Small amplified RNA-SAGE: an alternative approach to study transcriptome from limiting amount of mRNA.
Nucleic acids research 2003;31(6):e24.
2003: Blanpain Cédric; Doranz Benjamin J; Bondue Antoine; Govaerts Cédric; De Leener Anne; Vassart Gilbert; Doms Robert W; Proudfoot Amanda; Parmentier Marc
The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle.
The Journal of biological chemistry 2003;278(7):5179-87.
2003: Gonzalez-Merino Eric; Emiliani Serena; Vassart Gilbert; Van den Bergh Marc; Vannin Anne-Sophie; Abramowicz Marc; Delneste Danièle; Englert Yvon
Incidence of chromosomal mosaicism in human embryos at different developmental stages analyzed by fluorescence in situ hybridization.
Genetic testing 2003;7(2):85-95.
2002: Costagliola Sabine; Vassart Gilbert
Monoclonal antibodies with thyroid stimulating activity, at last.
Thyroid : official journal of the American Thyroid Association 2002;12(12):1039-41.
2002: Costagliola S; Franssen J D F; Bonomi M; Urizar E; Willnich M; Bergmann A; Vassart G
Generation of a mouse monoclonal TSH receptor antibody with stimulating activity.
Biochemical and biophysical research communications 2002;299(5):891-6.
2002: Torfs Herbert; Akerman Karl E; Nachman Ronald J; Oonk Hendrica B; Detheux Michel; Poels Jeroen; Loy Tom Van; Loof Arnold De; Meloen Rob H; Vassart Gilbert; Parmentier Marc; Broeck Jozef Vanden
Functional analysis of synthetic insectatachykinin analogs on recombinant neurokinin receptor expressing cell lines.
Peptides 2002;23(11):1999-2005.
2002: Perry Rebecca; Heinrichs Claudine; Bourdoux Pierre; Khoury Khalil; Szöts François; Dussault Jean H; Vassart Gilbert; Van Vliet Guy
Discordance of monozygotic twins for thyroid dysgenesis: implications for screening and for molecular pathophysiology.
The Journal of clinical endocrinology and metabolism 2002;87(9):4072-7.
2002: Vanvooren V; Uchino S; Duprez L; Costa M J; Vandekerckhove J; Parma J; Vassart G; Dumont J E; Van Sande J; Noguchi S
Oncogenic mutations in the thyrotropin receptor of autonomously functioning thyroid nodules in the Japanese population.
European journal of endocrinology / European Federation of Endocrine Societies 2002;147(3):287-91.
2002: Torfs Herbert; Detheux Michel; Oonk Hendrica B; Akerman Karl E; Poels Jeroen; Van Loy Tom; De Loof Arnold; Vassart Gilbert; Parmentier Marc; Vanden Broeck Jozef
Analysis of C-terminally substituted tachykinin-like peptide agonists by means of aequorin-based luminescent assays for human and insect neurokinin receptors.
Biochemical pharmacology 2002;63(9):1675-82.
2002: Torfs Herbert; Poels Jeroen; Detheux Michel; Dupriez Vincent; Van Loy Tom; Vercammen Linda; Vassart Gilbert; Parmentier Marc; Vanden Broeck Jozef
Recombinant aequorin as a reporter for receptor-mediated changes of intracellular Ca2+ -levels in Drosophila S2 cells.
Invertebrate neuroscience : IN 2002;4(3):119-24.
2002: Claeysen Sylvie; Govaerts Cédric; Lefort Anne; Van Sande Jacqueline; Costagliola Sabine; Pardo Leonardo; Vassart Gilbert
A conserved Asn in TM7 of the thyrotropin receptor is a common requirement for activation by both mutations and its natural agonist.
FEBS letters 2002;517(1-3):195-200.
2002: Vlaeminck-Guillem Virginie; Ho Su-Chin; Rodien Patrice; Vassart Gilbert; Costagliola Sabine
Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist.
Molecular endocrinology (Baltimore, Md.) 2002;16(4):736-46.
2002: Smits Guillaume; Govaerts Cédric; Nubourgh Isabelle; Pardo Leonardo; Vassart Gilbert; Costagliola Sabine
Lysine 183 and glutamic acid 157 of the TSH receptor: two interacting residues with a key role in determining specificity toward TSH and human CG.
Molecular endocrinology (Baltimore, Md.) 2002;16(4):722-35.
2002: Blanpain Cédric; Vanderwinden Jean-Marie; Cihak Josef; Wittamer Valérie; Le Poul Emmanuel; Issafras Hassan; Stangassinger Manfred; Vassart Gilbert; Marullo Stefano; Schlndorff Detlef; Parmentier Marc; Mack Matthias
Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies.
Molecular biology of the cell 2002;13(2):723-37.
2002: Costagliola S; Panneels V; Bonomi M; Koch J; Many M C; Smits G; Vassart G
Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors.
The EMBO journal 2002;21(4):504-13.
2002: Vassart G; Abramowicz M; Cochaux P; Duprez L; el Housni H; Hayez F; Heimann P; Parma J; Vamos E; Van Regemorter N
[Medical genetics service]
Revue médicale de Bruxelles 2002;23 Suppl 2():63-7.
2002: Blanpain Cédric; Libert Frédérick; Vassart Gilbert; Parmentier Marc
CCR5 and HIV infection.
Receptors & channels 2002;8(1):19-31.
2001: Bretones P; Duprez L; Parma J; David M; Vassart G; Rodien P
A familial case of congenital hypothyroidism caused by a homozygous mutation of the thyrotropin receptor gene.
Thyroid : official journal of the American Thyroid Association 2001;11(10):977-80.
2001: Mendive F M; Rivolta C M; Moya C M; Vassart G; Targovnik H M
Genomic organization of the human thyroglobulin gene: the complete intron-exon structure.
European journal of endocrinology / European Federation of Endocrine Societies 2001;145(4):485-96.
2001: Vakili J; Ständker L; Detheux M; Vassart G; Forssmann W G; Parmentier M
Urokinase plasminogen activator and plasmin efficiently convert hemofiltrate CC chemokine 1 into its active.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(6):3406-13.
2001: Kotani M; Detheux M; Vandenbogaerde A; Communi D; Vanderwinden J M; Le Poul E; Brézillon S; Tyldesley R; Suarez-Huerta N; Vandeput F; Blanpain C; Schiffmann S N; Vassart G; Parmentier M
The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54.
The Journal of biological chemistry 2001;276(37):34631-6.
2001: Corvilain B; Van Sande J; Dumont J E; Vassart G
Somatic and germline mutations of the TSH receptor and thyroid diseases.
Clinical endocrinology 2001;55(2):143-58.
2001: Cornelis S; Uttenweiler-Joseph S; Panneels V; Vassart G; Costagliola S
Purification and characterization of a soluble bioactive amino-terminal extracellular domain of the human thyrotropin receptor.
Biochemistry 2001;40(33):9860-9.
2001: Ho S C; Van Sande J; Lefort A; Vassart G; Costagliola S
Effects of mutations involving the highly conserved S281HCC motif in the extracellular domain of the thyrotropin (TSH) receptor on TSH binding and constitutive activity.
Endocrinology 2001;142(7):2760-7.
2001: Gulbis B; Cotton F; Hansen V; Ferster A; Toppet M; Cochaux P; Parma J; Vassart G; Fondu P; Vertongen F
[Prevention of hemoglobinopathies in Brussels: a necessity?]
Revue médicale de Bruxelles 2001;22(3):133-40.
2001: Blanpain C; Wittamer V; Vanderwinden J M; Boom A; Renneboog B; Lee B; Le Poul E; El Asmar L; Govaerts C; Vassart G; Doms R W; Parmentier M
Palmitoylation of CCR5 is critical for receptor trafficking and efficient activation of intracellular signaling pathways.
The Journal of biological chemistry 2001;276(26):23795-804.
2001: Govaerts C; Lefort A; Costagliola S; Wodak S J; Ballesteros J A; Van Sande J; Pardo L; Vassart G
A conserved Asn in transmembrane helix 7 is an on/off switch in the activation of the thyrotropin receptor.
The Journal of biological chemistry 2001;276(25):22991-9.
2001: Kotani M; Mollereau C; Detheux M; Le Poul E; Brézillon S; Vakili J; Mazarguil H; Vassart G; Zajac J M; Parmentier M
Functional characterization of a human receptor for neuropeptide FF and related peptides.
British journal of pharmacology 2001;133(1):138-44.
2001: Demeester R; Parma J; Cochaux P; Vassart G; Abramowicz M J
A rare variant, I852M, of the RET proto-oncogene in a patient with medullary thyroid carcinoma at age 20 years.
Human mutation 2001;17(4):354.
2001: Govaerts C; Blanpain C; Deupi X; Ballet S; Ballesteros J A; Wodak S J; Vassart G; Pardo L; Parmentier M
The TXP motif in the second transmembrane helix of CCR5. A structural determinant of chemokine-induced activation.
The Journal of biological chemistry 2001;276(16):13217-25.
2001: Vilain C; Rydlewski C; Duprez L; Heinrichs C; Abramowicz M; Malvaux P; Renneboog B; Parma J; Costagliola S; Vassart G
Autosomal dominant transmission of congenital thyroid hypoplasia due to loss-of-function mutation of PAX8.
The Journal of clinical endocrinology and metabolism 2001;86(1):234-8.
2000: Emiliani S; Merino E G; Van den Bergh M; Abramowicz M; Vassart G; Englert Y; Delneste D
Re-analysis by fluorescence in situ hybridisation of spare embryos cultured until Day 5 after preimplantation genetic diagnosis for a 47, XYY infertile patient demonstrates a high incidence of diploid mosaic embryos: a case report.
Prenatal diagnosis 2000;20(13):1063-6.
2000: Moya C M; Mendive F M; Rivolta C M; Vassart G; Targovnik H M
Genomic organization of the 5' region of the human thyroglobulin gene.
European journal of endocrinology / European Federation of Endocrine Societies 2000;143(6):789-98.
2000: Detheux M; Ständker L; Vakili J; Münch J; Forssmann U; Adermann K; Pöhlmann S; Vassart G; Kirchhoff F; Parmentier M; Forssmann W G
Natural proteolytic processing of hemofiltrate CC chemokine 1 generates a potent CC chemokine receptor (CCR)1 and CCR5 agonist with anti-HIV properties.
The Journal of experimental medicine 2000;192(10):1501-8.
2000: Mircescu H; Parma J; Huot C; Deal C; Oligny L L; Vassart G; Van Vliet G
Hyperfunctioning malignant thyroid nodule in an 11-year-old girl: pathologic and molecular studies.
The Journal of pediatrics 2000;137(4):585-7.
2000: Blanpain C; Lee B; Tackoen M; Puffer B; Boom A; Libert F; Sharron M; Wittamer V; Vassart G; Doms R W; Parmentier M
Multiple nonfunctional alleles of CCR5 are frequent in various human populations.
Blood 2000;96(5):1638-45.
2000: Pohlenz J; Duprez L; Weiss R E; Vassart G; Refetoff S; Costagliola S
Failure of membrane targeting causes the functional defect of two mutant sodium iodide symporters.
The Journal of clinical endocrinology and metabolism 2000;85(7):2366-9.
2000: De Deken X; Wang D; Many M C; Costagliola S; Libert F; Vassart G; Dumont J E; Miot F
Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family.
The Journal of biological chemistry 2000;275(30):23227-33.
2000: Heinrichs C; Parma J; Scherberg N H; Delange F; Van Vliet G; Duprez L; Bourdoux P; Bergmann P; Vassart G; Refetoff S
Congenital central isolated hypothyroidism caused by a homozygous mutation in the TSH-beta subunit gene.
Thyroid : official journal of the American Thyroid Association 2000;10(5):387-91.
2000: Costagliola S; Many M C; Denef J F; Pohlenz J; Refetoff S; Vassart G
Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease.
The Journal of clinical investigation 2000;105(6):803-11.
1999: Blanpain C; Doranz B J; Vakili J; Rucker J; Govaerts C; Baik S S; Lorthioir O; Migeotte I; Libert F; Baleux F; Vassart G; Doms R W; Parmentier M
Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein.
The Journal of biological chemistry 1999;274(49):34719-27.
1999: Costagliola S; Sunthorntepvarakul T; Migeotte I; Van Sande J; Kajava A M; Refetoff S; Vassart G
Structure-function relationships of two loss-of-function mutations of the thyrotropin receptor gene.
Thyroid : official journal of the American Thyroid Association 1999;9(10):995-1000.
1999: Mendive F M; Rivolta C M; Vassart G; Targovnik H M
Genomic organization of the 3' region of the human thyroglobulin gene.
Thyroid : official journal of the American Thyroid Association 1999;9(9):903-12.
1999: Tiosano D; Pannain S; Vassart G; Parma J; Gershoni-Baruch R; Mandel H; Lotan R; Zaharan Y; Pery M; Weiss R E; Refetoff S; Hochberg Z
The hypothyroidism in an inbred kindred with congenital thyroid hormone and glucocorticoid deficiency is due to a mutation producing a truncated thyrotropin receptor.
Thyroid : official journal of the American Thyroid Association 1999;9(9):887-94.
1999: Blanpain C; Migeotte I; Lee B; Vakili J; Doranz B J; Govaerts C; Vassart G; Doms R W; Parmentier M
CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist.
Blood 1999;94(6):1899-905.
1999: Pichon B; Vassart G; Christophe D
A canonical nerve growth factor-induced gene-B response element appears not to be involved in the cyclic adenosine monophosphate-dependent expression of differentiation in thyrocytes.
Molecular and cellular endocrinology 1999;154(1-2):21-7.
1999: Blanpain C; Lee B; Vakili J; Doranz B J; Govaerts C; Migeotte I; Sharron M; Dupriez V; Vassart G; Doms R W; Parmentier M
Extracellular cysteines of CCR5 are required for chemokine binding, but dispensable for HIV-1 coreceptor activity.
The Journal of biological chemistry 1999;274(27):18902-8.
1999: Duprez L; Parma J; Van Sande J; Rodien P; Sabine C; Abramowicz M; Dumont J E; Vassart G
Pathology of the TSH receptor.
Journal of pediatric endocrinology & metabolism : JPEM 1999;12 Suppl 1():295-302.
1999: Many M C; Costagliola S; Detrait M; Denef F; Vassart G; Ludgate M C
Development of an animal model of autoimmune thyroid eye disease.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(8):4966-74.
1999: Khoo D H; Parma J; Rajasoorya C; Ho S C; Vassart G
A germline mutation of the thyrotropin receptor gene associated with thyrotoxicosis and mitral valve prolapse in a Chinese family.
The Journal of clinical endocrinology and metabolism 1999;84(4):1459-62.
1999: Maho A; Bensimon A; Vassart G; Parmentier M
Mapping of the CCXCR1, CX3CR1, CCBP2 and CCR9 genes to the CCR cluster within the 3p21.3 region of the human genome.
Cytogenetics and cell genetics 1999;87(3-4):265-8.
1998: Rodien P; Brémont C; Sanson M L; Parma J; Van Sande J; Costagliola S; Luton J P; Vassart G; Duprez L
Familial gestational hyperthyroidism caused by a mutant thyrotropin receptor hypersensitive to human chorionic gonadotropin.
The New England journal of medicine 1998;339(25):1823-6.
1998: Rodien P; Cetani F; Costagliola S; Tonacchera M; Duprez L; Minegishi T; Govaerts C; Vassart G
Evidences for an allelic variant of the human LC/CG receptor rather than a gene duplication: functional comparison of wild-type and variant receptors.
The Journal of clinical endocrinology and metabolism 1998;83(12):4431-4.
1998: Duprez L; Parma J; Van Sande J; Rodien P; Dumont J E; Vassart G; Abramowicz M
TSH Receptor Mutations and Thyroid Disease.
Trends in endocrinology and metabolism: TEM 1998;9(4):133-40.
1998: Ludgate M; Crisp M; Lane C; Costagliola S; Vassart G; Weetman A; Daunerie C; Many M C
The thyrotropin receptor in thyroid eye disease.
Thyroid : official journal of the American Thyroid Association 1998;8(5):411-3.
1998: Samson M; Edinger A L; Stordeur P; Rucker J; Verhasselt V; Sharron M; Govaerts C; Mollereau C; Vassart G; Doms R W; Parmentier M
ChemR23, a putative chemoattractant receptor, is expressed in monocyte-derived dendritic cells and macrophages and is a coreceptor for SIV and some primary HIV-1 strains.
European journal of immunology 1998;28(5):1689-700.
1998: Gagné N; Parma J; Deal C; Vassart G; Van Vliet G
Apparent congenital athyreosis contrasting with normal plasma thyroglobulin levels and associated with inactivating mutations in the thyrotropin receptor gene: are athyreosis and ectopic thyroid distinct entities?
The Journal of clinical endocrinology and metabolism 1998;83(5):1771-5.
1998: Targovnik H M; Frechtel G D; Mendive F M; Vono J; Cochaux P; Vassart G; Medeiros-Neto G
Evidence for the segregation of three different mutated alleles of the thyroglobulin gene in a Brazilian family with congenital goiter and hypothyroidism.
Thyroid : official journal of the American Thyroid Association 1998;8(4):291-7.
1998: Libert F; Cochaux P; Beckman G; Samson M; Aksenova M; Cao A; Czeizel A; Claustres M; de la Rúa C; Ferrari M; Ferrec C; Glover G; Grinde B; Güran S; Kucinskas V; Lavinha J; Mercier B; Ogur G; Peltonen L; Rosatelli C; Schwartz M; Spitsyn V; Timar L; Beckman L; Parmentier M; Vassart G
The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe.
Human molecular genetics 1998;7(3):399-406.
1998: Costagliola S; Rodien P; Many M C; Ludgate M; Vassart G
Genetic immunization against the human thyrotropin receptor causes thyroiditis and allows production of monoclonal antibodies recognizing the native receptor.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(3):1458-65.
1997: Xie J; Pannain S; Pohlenz J; Weiss R E; Moltz K; Morlot M; Asteria C; Persani L; Beck-Peccoz P; Parma J; Vassart G; Refetoff S
Resistance to thyrotropin (TSH) in three families is not associated with mutations in the TSH receptor or TSH.
The Journal of clinical endocrinology and metabolism 1997;82(12):3933-40.
1997: Samson M; LaRosa G; Libert F; Paindavoine P; Detheux M; Vassart G; Parmentier M
The second extracellular loop of CCR5 is the major determinant of ligand specificity.
The Journal of biological chemistry 1997;272(40):24934-41.
1997: Mendive F M; Rossetti L C; Vassart G; Targovnik H M
Identification of a new thyroglobulin variant: a guanine-to-adenine transition resulting in the substitution of arginine 2510 by glutamine.
Thyroid : official journal of the American Thyroid Association 1997;7(4):587-91.
1997: Vanderhaeghen P; Schurmans S; Vassart G; Parmentier M
Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome.
Biochemical and biophysical research communications 1997;237(2):283-7.
1997: Parma J; Duprez L; Van Sande J; Hermans J; Rocmans P; Van Vliet G; Costagliola S; Rodien P; Dumont J E; Vassart G
Diversity and prevalence of somatic mutations in the thyrotropin receptor and Gs alpha genes as a cause of toxic thyroid adenomas.
The Journal of clinical endocrinology and metabolism 1997;82(8):2695-701.
1997: Duprez L; Parma J; Costagliola S; Hermans J; Van Sande J; Dumont J E; Vassart G
Constitutive activation of the TSH receptor by spontaneous mutations affecting the N-terminal extracellular domain.
FEBS letters 1997;409(3):469-74.
1997: Abramowicz M J; Duprez L; Parma J; Vassart G; Heinrichs C
Familial congenital hypothyroidism due to inactivating mutation of the thyrotropin receptor causing profound hypoplasia of the thyroid gland.
The Journal of clinical investigation 1997;99(12):3018-24.
1997: Berg V; Vassart G; Christophe D
A zinc-dependent DNA-binding activity co-operates with cAMP-responsive-element-binding protein to activate the human thyroglobulin enhancer.
The Biochemical journal 1997;323 ( Pt 2)():349-57.
1997: Rana S; Besson G; Cook D G; Rucker J; Smyth R J; Yi Y; Turner J D; Guo H H; Du J G; Peiper S C; Lavi E; Samson M; Libert F; Liesnard C; Vassart G; Doms R W; Parmentier M; Collman R G
Role of CCR5 in infection of primary macrophages and lymphocytes by macrophage-tropic strains of human immunodeficiency virus: resistance to patient-derived and prototype isolates resulting from the delta ccr5 mutation.
Journal of virology 1997;71(4):3219-27.
1997: Vanderhaeghen P; Schurmans S; Vassart G; Parmentier M
Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.
Genomics 1997;39(3):239-46.
1997: Duprez L; Hermans J; Van Sande J; Dumont J E; Vassart G; Parma J
Two autonomous nodules of a patient with multinodular goiter harbor different activating mutations of the thyrotropin receptor gene.
The Journal of clinical endocrinology and metabolism 1997;82(1):306-8.
1997: Ledent C; Denef J F; Cottecchia S; Lefkowitz R; Dumont J; Vassart G; Parmentier M
Costimulation of adenylyl cyclase and phospholipase C by a mutant alpha 1B-adrenergic receptor transgene promotes malignant transformation of thyroid follicular cells.
Endocrinology 1997;138(1):369-78.
1997: Vassart G
New pathophysiological mechanisms for hyperthyroidism.
Hormone research 1997;48 Suppl 4():47-50.
1997: Uyttersprot N; Allgeier A; Baptist M; Christophe D; Coppee F; Coulonval K; Deleu S; Depoortere F; Dremier S; Lamy F; Ledent C; Maenhaut C; Miot F; Panneels V; Parma J; Parmentier M; Pirson I; Pohl V; Roger P; Savonet V; Taton M; Tonacchera M; van Sande J; Wilkin F; Vassart G
The cAMP in thyroid: from the TSH receptor to mitogenesis and tumorigenesis.
Advances in second messenger and phosphoprotein research 1997;31():125-40.
1996: Samson M; Stordeur P; Labbé O; Soularue P; Vassart G; Parmentier M
Molecular cloning and chromosomal mapping of a novel human gene, ChemR1, expressed in T lymphocytes and polymorphonuclear cells and encoding a putative chemokine receptor.
European journal of immunology 1996;26(12):3021-8.
1996: Dremier S; Coppée F; Delange F; Vassart G; Dumont J E; Van Sande J
Clinical review 84: Thyroid autonomy: mechanism and clinical effects.
The Journal of clinical endocrinology and metabolism 1996;81(12):4187-93.
1996: Rucker J; Samson M; Doranz B J; Libert F; Berson J F; Yi Y; Smyth R J; Collman R G; Broder C C; Vassart G; Doms R W; Parmentier M
Regions in beta-chemokine receptors CCR5 and CCR2b that determine HIV-1 cofactor specificity.
Cell 1996;87(3):437-46.
1996: Costagliola S; Many M C; Stalmans-Falys M; Vassart G; Ludgate M
Transfer of thyroiditis, with syngeneic spleen cells sensitized with the human thyrotropin receptor, to naive BALB/c and NOD mice.
Endocrinology 1996;137(11):4637-43.
1996: Tonacchera M; Cetani F; Parma J; Van Sande J; Vassart G; Dumont J
Oncogenic mutations in thyroid adenoma: methodological criteria.
European journal of endocrinology / European Federation of Endocrine Societies 1996;135(4):444-6.
1996: Coppée F; Gérard A C; Denef J F; Ledent C; Vassart G; Dumont J E; Parmentier M
Early occurrence of metastatic differentiated thyroid carcinomas in transgenic mice expressing the A2a adenosine receptor gene and the human papillomavirus type 16 E7 oncogene.
Oncogene 1996;13(7):1471-82.
1996: Samson M; Soularue P; Vassart G; Parmentier M
The genes encoding the human CC-chemokine receptors CC-CKR1 to CC-CKR5 (CMKBR1-CMKBR5) are clustered in the p21.3-p24 region of chromosome 3.
Genomics 1996;36(3):522-6.
1996: Samson M; Libert F; Doranz B J; Rucker J; Liesnard C; Farber C M; Saragosti S; Lapoumeroulie C; Cognaux J; Forceille C; Muyldermans G; Verhofstede C; Burtonboy G; Georges M; Imai T; Rana S; Yi Y; Smyth R J; Collman R G; Doms R W; Vassart G; Parmentier M
Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene.
Nature 1996;382(6593):722-5.
1996: Tonacchera M; Van Sande J; Parma J; Duprez L; Cetani F; Costagliola S; Dumont J E; Vassart G
TSH receptor and disease.
Clinical endocrinology 1996;44(6):621-33.
1996: Tonacchera M; Cetani F; Costagliola S; Van Sande J; Refetoff S; Vassart G
Functional characteristics of a variant thyrotropin receptor.
European journal of biochemistry / FEBS 1996;238(2):490-4.
1996: Van Renterghem P; Vassart G; Christophe D
Pax 8 expression in primary cultured dog thyrocyte is increased by cyclic AMP.
Biochimica et biophysica acta 1996;1307(1):97-103.
1996: Berg V; Vassart G; Christophe D
Identification of a thyroid-specific and cAMP-responsive enhancer in the upstream sequences of the human thyroglobulin promoter.
Biochimica et biophysica acta 1996;1307(1):35-8.
1996: Van Sande J; Massart C; Costagliola S; Allgeier A; Cetani F; Vassart G; Dumont J E
Specific activation of the thyrotropin receptor by trypsin.
Molecular and cellular endocrinology 1996;119(2):161-8.
1996: Tonacchera M; Van Sande J; Cetani F; Swillens S; Schvartz C; Winiszewski P; Portmann L; Dumont J E; Vassart G; Parma J
Functional characteristics of three new germline mutations of the thyrotropin receptor gene causing autosomal dominant toxic thyroid hyperplasia.
The Journal of clinical endocrinology and metabolism 1996;81(2):547-54.
1996: Paschke R; Van Sande J; Parma J; Vassart G
The TSH receptor and thyroid diseases.
Baillière's clinical endocrinology and metabolism 1996;10(1):9-27.
1996: Tonacchera M; Costagliola S; Cetani F; Ducobu J; Stordeur P; Vassart G; Ludgate M
Patient with monoclonal gammopathy, thyrotoxicosis, pretibial myxedema and thyroid-associated ophthalmopathy; demonstration of direct binding of autoantibodies to the thyrotropin receptor.
European journal of endocrinology / European Federation of Endocrine Societies 1996;134(1):97-103.
1996: Cetani F; Tonacchera M; Vassart G
Differential effects of NaCl concentration on the constitutive activity of the thyrotropin and the luteinizing hormone/chorionic gonadotropin receptors.
FEBS letters 1996;378(1):27-31.
1996: Ledent C; Coppée F; Dumont J E; Vassart G; Parmentier M
Transgenic models for proliferative and hyperfunctional thyroid diseases.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1996;104 Suppl 3():43-6.
1996: Vassart G; Van Sande J; Parma J; Tonacchera M; Duprez L; Swillens S; Dumont J
Activating mutations of the TSH receptor gene cause thyroid diseases.
Annales d'endocrinologie 1996;57(1):50-4.
1995: Costagliola S; Many M C; Stalmans-Falys M; Vassart G; Ludgate M
The autoimmune response induced by immunising female mice with recombinant human thyrotropin receptor varies with the genetic background.
Molecular and cellular endocrinology 1995;115(2):199-206.
1995: Cetani F; Costagliola S; Tonacchera M; Panneels V; Vassart G; Ludgate M
The thyroperoxidase doublet is not produced by alternative splicing.
Molecular and cellular endocrinology 1995;115(2):125-32.
1995: Van Sande J; Parma J; Tonacchera M; Swillens S; Dumont J; Vassart G
Somatic and germline mutations of the TSH receptor gene in thyroid diseases.
The Journal of clinical endocrinology and metabolism 1995;80(9):2577-85.
1995: Vassart G; Desarnaud F; Duprez L; Eggerickx D; Labbé O; Libert F; Mollereau C; Parma J; Paschke R; Tonacchera M
The G protein-coupled receptor family and one of its members, the TSH receptor.
Annals of the New York Academy of Sciences 1995;766():23-30.
1995: Eggerickx D; Denef J F; Labbe O; Hayashi Y; Refetoff S; Vassart G; Parmentier M; Libert F
Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase.
The Biochemical journal 1995;309 ( Pt 3)():837-43.
1995: Van Renterghem P; Dremier S; Vassart G; Christophe D
Study of TTF-1 gene expression in dog thyrocytes in primary culture.
Molecular and cellular endocrinology 1995;112(1):83-93.
1995: Parma J; Van Sande J; Swillens S; Tonacchera M; Dumont J; Vassart G
Somatic mutations causing constitutive activity of the thyrotropin receptor are the major cause of hyperfunctioning thyroid adenomas: identification of additional mutations activating both the cyclic adenosine 3',5'-monophosphate and inositol phosphate-Ca2+ cascades.
Molecular endocrinology (Baltimore, Md.) 1995;9(6):725-33.
1995: Ledent C; Marcotte A; Dumont J E; Vassart G; Parmentier M
Differentiated carcinomas develop as a consequence of the thyroid specific expression of a thyroglobulin-human papillomavirus type 16 E7 transgene.
Oncogene 1995;10(9):1789-97.
1995: Van Sande J; Swillens S; Gerard C; Allgeier A; Massart C; Vassart G; Dumont J E
In Chinese hamster ovary K1 cells dog and human thyrotropin receptors activate both the cyclic AMP and the phosphatidylinositol 4,5-bisphosphate cascades in the presence of thyrotropin and the cyclic AMP cascade in its absence.
European journal of biochemistry / FEBS 1995;229(2):338-43.
1995: Kopp P; van Sande J; Parma J; Duprez L; Gerber H; Joss E; Jameson J L; Dumont J E; Vassart G
Brief report: congenital hyperthyroidism caused by a mutation in the thyrotropin-receptor gene.
The New England journal of medicine 1995;332(3):150-4.
1995: Ludgate M E; Vassart G
The thyrotropin receptor as a model to illustrate receptor and receptor antibody diseases.
Baillière's clinical endocrinology and metabolism 1995;9(1):95-113.
1995: Tonacchera M; Cetani F; Costagliola S; Alcalde L; Uibo R; Vassart G; Ludgate M
Mapping thyroid peroxidase epitopes using recombinant protein fragments.
European journal of endocrinology / European Federation of Endocrine Societies 1995;132(1):53-61.
1994: Paschke R; Tonacchera M; Van Sande J; Parma J; Vassart G
Identification and functional characterization of two new somatic mutations causing constitutive activation of the thyrotropin receptor in hyperfunctioning autonomous adenomas of the thyroid.
The Journal of clinical endocrinology and metabolism 1994;79(6):1785-9.
1994: Paschke R; Metcalfe A; Alcalde L; Vassart G; Weetman A; Ludgate M
Presence of nonfunctional thyrotropin receptor variant transcripts in retroocular and other tissues.
The Journal of clinical endocrinology and metabolism 1994;79(5):1234-8.
1994: Costagliola S; Many M C; Stalmans-Falys M; Tonacchera M; Vassart G; Ludgate M
Recombinant thyrotropin receptor and the induction of autoimmune thyroid disease in BALB/c mice: a new animal model.
Endocrinology 1994;135(5):2150-9.
1994: Costagliola S; Alcalde L; Ruf J; Vassart G; Ludgate M
Overexpression of the extracellular domain of the thyrotrophin receptor in bacteria; production of thyrotrophin-binding inhibiting immunoglobulins.
Journal of molecular endocrinology 1994;13(1):11-21.
1994: Desarnaud F; Labbe O; Eggerickx D; Vassart G; Parmentier M
Molecular cloning, functional expression and pharmacological characterization of a mouse melanocortin receptor gene.
The Biochemical journal 1994;299 ( Pt 2)():367-73.
1994: Labbé O; Desarnaud F; Eggerickx D; Vassart G; Parmentier M
Molecular cloning of a mouse melanocortin 5 receptor gene widely expressed in peripheral tissues.
Biochemistry 1994;33(15):4543-9.
1994: Ledent C; Parmentier M; Vassart G; Dumont J E
Models of thyroid goiter and tumors in transgenic mice.
Molecular and cellular endocrinology 1994;100(1-2):167-9.
1994: Parma J; Duprez L; Van Sande J; Paschke R; Tonacchera M; Dumont J; Vassart G
Constitutively active receptors as a disease-causing mechanism.
Molecular and cellular endocrinology 1994;100(1-2):159-62.
1994: Pichon B; Christophe-Hobertus C; Vassart G; Christophe D
Unmethylated thyroglobulin promoter may be repressed by methylation of flanking DNA sequences.
The Biochemical journal 1994;298 Pt 3():537-41.
1994: Costagliola S; Alcalde L; Tonacchera M; Ruf J; Vassart G; Ludgate M
Induction of thyrotropin receptor (TSH-R) autoantibodies and thyroiditis in mice immunised with the recombinant TSH-R.
Biochemical and biophysical research communications 1994;199(2):1027-34.
1994: Ledent C; Parma J; Dumont J; Vassart G; Targovnik H
Molecular genetics of thyroid diseases.
European journal of endocrinology / European Federation of Endocrine Societies 1994;130(1):8-14.
1993: Vanderhaeghen P; Schurmans S; Vassart G; Parmentier M
Olfactory receptors are displayed on dog mature sperm cells.
The Journal of cell biology 1993;123(6 Pt 1):1441-52.
1993: Parma J; Duprez L; Van Sande J; Cochaux P; Gervy C; Mockel J; Dumont J; Vassart G
Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas.
Nature 1993;365(6447):649-51.
1993: Van Sande J; Allgeier A; Massart C; Czernilofsky A; Vassart G; Dumont J E; Maenhaut C
The human and dog 5-HT1D receptors can both activate and inhibit adenylate cyclase in transfected cells.
European journal of pharmacology 1993;247(2):177-84.
1993: Targovnik H M; Medeiros-Neto G; Varela V; Cochaux P; Wajchenberg B L; Vassart G
A nonsense mutation causes human hereditary congenital goiter with preferential production of a 171-nucleotide-deleted thyroglobulin ribonucleic acid messenger.
The Journal of clinical endocrinology and metabolism 1993;77(1):210-5.
1993: Targovnik H M; Frechtel G D; Varela V; Wajchenberg B L; Vassart G; Dumont J; Medeiros-Neto G A
Human thyroid tissue do not express thyroalbumin.
Journal of endocrinological investigation 1993;16(6):415-9.
1993: Paschke R; Elisei R; Vassart G; Ludgate M
Lack of evidence supporting the presence of mRNA for the thyrotropin receptor in extra-ocular muscle.
Journal of endocrinological investigation 1993;16(5):329-32.
1993: Mollereau C; Muscatelli F; Mattei M G; Vassart G; Parmentier M
The high-affinity interleukin 8 receptor gene (IL8RA) maps to the 2q33-q36 region of the human genome: cloning of a pseudogene (IL8RBP) for the low-affinity receptor.
Genomics 1993;16(1):248-51.
1993: Donda A; Javaux F; Van Renterghem P; Gervy-Decoster C; Vassart G; Christophe D
Human, bovine, canine and rat thyroglobulin promoter sequences display species-specific differences in an in vitro study.
Molecular and cellular endocrinology 1993;90(2):R23-6.
1993: Parmentier M; Libert F; Perret J; Eggerickx D; Ledent C; Schurmans S; Raspe E; Dumont J E; Vassart G
Cloning and characterization of G protein-coupled receptors.
Advances in second messenger and phosphoprotein research 1993;28():11-8.
1993: Schurmans S; Muscatelli F; Miot F; Mattei M G; Vassart G; Parmentier M
The OLFR1 gene encoding the HGMP07E putative olfactory receptor maps to the 17p13-->p12 region of the human genome and reveals an MspI restriction fragment length polymorphism.
Cytogenetics and cell genetics 1993;63(3):200-4.
1993: Vassart G
[Molecular genetics of thyroid diseases]
Bulletin et mémoires de l'Académie royale de médecine de Belgique 1993;148(10):337-41.
1993: Vassart G; Parma J; Duprez L; Maenhaut C; Ledent C; Van Sande J; Brabant G; Dumont J
[Thyrotropin receptor. Control of the gene expression and structure function relationships]
Annales d'endocrinologie 1993;54(6):367-8.
1992: Costagliola S; Swillens S; Niccoli P; Dumont J E; Vassart G; Ludgate M
Binding assay for thyrotropin receptor autoantibodies using the recombinant receptor protein.
The Journal of clinical endocrinology and metabolism 1992;75(6):1540-4.
1992: Christophe-Hobertus C; Donda A; Javaux F; Vassart G; Christophe D
Identification of a transcriptional enhancer upstream from the bovine thyroglobulin gene.
Molecular and cellular endocrinology 1992;88(1-3):31-7.
1992: Abramowicz M J; Targovnik H M; Varela V; Cochaux P; Krawiec L; Pisarev M A; Propato F V; Juvenal G; Chester H A; Vassart G
Identification of a mutation in the coding sequence of the human thyroid peroxidase gene causing congenital goiter.
The Journal of clinical investigation 1992;90(4):1200-4.
1992: Van Sande J; Lejeune C; Ludgate M; Munro D S; Vassart G; Dumont J E; Mockel J
Thyroid stimulating immunoglobulins, like thyrotropin activate both the cyclic AMP and the PIP2 cascades in CHO cells expressing the TSH receptor.
Molecular and cellular endocrinology 1992;88(1-3):R1-5.
1992: Erneux C; Roeckel N; Takazawa K; Mailleux P; Vassart G; Mattei M G
Localization of the genes for human inositol 1,4,5-trisphosphate 3-kinase A (ITPKA) and B (ITPKB) to chromosome regions 15q14-q21 and 1q41-q43, respectively, by in situ hybridization.
Genomics 1992;14(2):546-7.
1992: Libert F; Van Sande J; Lefort A; Czernilofsky A; Dumont J E; Vassart G; Ensinger H A; Mendla K D
Cloning and functional characterization of a human A1 adenosine receptor.
Biochemical and biophysical research communications 1992;187(2):919-26.
1992: Eggerickx D; Raspe E; Bertrand D; Vassart G; Parmentier M
Molecular cloning, functional expression and pharmacological characterization of a human bradykinin B2 receptor gene.
Biochemical and biophysical research communications 1992;187(3):1306-13.
1992: Vassart G; Dumont J E
The thyrotropin receptor and the regulation of thyrocyte function and growth.
Endocrine reviews 1992;13(3):596-611.
1992: Javaux F; Bertaux F; Donda A; Francis-Lang H; Vassart G; DiLauro R; Christophe D
Functional role of TTF-1 binding sites in bovine thyroglobulin promoter.
FEBS letters 1992;300(3):222-6.
1992: Targovnik H M; Cochaux P; Corach D; Vassart G
Identification of a minor Tg mRNA transcript in RNA from normal and goitrous thyroids.
Molecular and cellular endocrinology 1992;84(1-2):R23-6.
1992: Ledent C; Dumont J E; Vassart G; Parmentier M
Thyroid expression of an A2 adenosine receptor transgene induces thyroid hyperplasia and hyperthyroidism.
The EMBO journal 1992;11(2):537-42.
1992: Maenhaut C; Brabant G; Vassart G; Dumont J E
In vitro and in vivo regulation of thyrotropin receptor mRNA levels in dog and human thyroid cells.
The Journal of biological chemistry 1992;267(5):3000-7.
1992: Vassart G; Brabant G; Costagliola S; Danguy D; Gérard C; Libert F; Ludgate M; Maenhaut C; Parmentier M; Paschke R
Molecular genetics of the thyrotropin receptor.
Experimental and clinical endocrinology 1992;100(1-2):9-11.
1992: Zhang Z G; Dong Q; Rodien P; Alcalde L; Bernard N; Boucher A; Salvi M; Arthurs B; Vassart G M; Ludgate M
Antibodies in the serum of patients with autoimmune thyroid disorders react with a recombinant 98 amino acid fragment of a full length 64 kDa eye muscle membrane protein which is also expressed in the thyroid.
Autoimmunity 1992;13(2):151-7.
1992: Ludgate M; Costagliola S; Danguy D; Perret J; Vassart G
Recombinant TSH-receptor for determination of TSH-receptor-antibodies.
Experimental and clinical endocrinology 1992;100(1-2):73-4.
1992: Vassart G; Parmentier M; Libert F; Eggerickx D; Gerard C; Maenhaut C; Mollereau C; Perret J; Schurman S; Van Sande J
Identification of orphan G protein-coupled receptors.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():147A-148A.
1991: Ieiri T; Cochaux P; Targovnik H M; Suzuki M; Shimoda S; Perret J; Vassart G
A 3' splice site mutation in the thyroglobulin gene responsible for congenital goiter with hypothyroidism.
The Journal of clinical investigation 1991;88(6):1901-5.
1991: Parmentier M; Passage E; Mattei M G; Vassart G
A new human hypervariable locus (K29) maps to the q37.3 region of chromosome 2 and reveals a fingerprint.
Genomics 1991;11(3):760-2.
1991: Maenhaut C; Van Sande J; Massart C; Dinsart C; Libert F; Monferini E; Giraldo E; Ladinsky H; Vassart G; Dumont J E
The orphan receptor cDNA RDC4 encodes a 5-HT1D serotonin receptor.
Biochemical and biophysical research communications 1991;180(3):1460-8.
1991: Donda A; Vassart G; Christophe D
Isolation and characterization of the canine thyroglobulin gene promoter region.
Biochimica et biophysica acta 1991;1090(2):235-7.
1991: Gérard C M; Mollereau C; Vassart G; Parmentier M
Molecular cloning of a human cannabinoid receptor which is also expressed in testis.
The Biochemical journal 1991;279 ( Pt 1)():129-34.
1991: Libert F; Ludgate M; Dinsart C; Vassart G
Thyroperoxidase, but not the thyrotropin receptor, contains sequential epitopes recognized by autoantibodies in recombinant peptides expressed in the pUEX vector.
The Journal of clinical endocrinology and metabolism 1991;73(4):857-60.
1991: Schiffmann S N; Libert F; Vassart G; Vanderhaeghen J J
Distribution of adenosine A2 receptor mRNA in the human brain.
Neuroscience letters 1991;130(2):177-81.
1991: Ledent C; Dumont J; Vassart G; Parmentier M
Thyroid adenocarcinomas secondary to tissue-specific expression of simian virus-40 large T-antigen in transgenic mice.
Endocrinology 1991;129(3):1391-401.
1991: Libert F; Passage E; Parmentier M; Simons M J; Vassart G; Mattei M G
Chromosomal mapping of A1 and A2 adenosine receptors, VIP receptor, and a new subtype of serotonin receptor.
Genomics 1991;11(1):225-7.
1991: Libert F; Schiffmann S N; Lefort A; Parmentier M; Gérard C; Dumont J E; Vanderhaeghen J J; Vassart G
The orphan receptor cDNA RDC7 encodes an A1 adenosine receptor.
The EMBO journal 1991;10(7):1677-82.
1991: Elisei R; Vassart G; Ludgate M
Demonstration of the existence of the alternatively spliced form of thyroid peroxidase in normal thyroid.
The Journal of clinical endocrinology and metabolism 1991;72(3):700-2.
1991: Javaux F; Donda A; Vassart G; Christophe D
Cloning and sequence analysis of TFE, a helix-loop-helix transcription factor able to recognize the thyroglobulin gene promoter in vitro.
Nucleic acids research 1991;19(5):1121-7.
1991: Cochaux P; Van Geffel R; Baran D; Vassart G
Prevalence of the major mutation of the CF gene in Belgian patients.
Advances in experimental medicine and biology 1991;290():353-4.
1991: Parmentier M; Passage E; Vassart G; Mattei M G
The human calbindin D28k (CALB1) and calretinin (CALB2) genes are located at 8q21.3----q22.1 and 16q22----q23, respectively, suggesting a common duplication with the carbonic anhydrase isozyme loci.
Cytogenetics and cell genetics 1991;57(1):41-3.
1990: Gérard C; Mollereau C; Vassart G; Parmentier M
Nucleotide sequence of a human cannabinoid receptor cDNA.
Nucleic acids research 1990;18(23):7142.
1990: Maenhaut C; Van Sande J; Libert F; Abramowicz M; Parmentier M; Vanderhaegen J J; Dumont J E; Vassart G; Schiffmann S
RDC8 codes for an adenosine A2 receptor with physiological constitutive activity.
Biochemical and biophysical research communications 1990;173(3):1169-78.
1990: Van Sande J; Raspé E; Perret J; Lejeune C; Maenhaut C; Vassart G; Dumont J E
Thyrotropin activates both the cyclic AMP and the PIP2 cascades in CHO cells expressing the human cDNA of TSH receptor.
Molecular and cellular endocrinology 1990;74(1):R1-6.
1990: Cochaux P; van Geffel R; Baran D; Poncin J; Vassart G
Prevalence of the delta F508 deletion of the cystic fibrosis gene in Belgian patients.
Human genetics 1990;85(4):400.
1990: Perret J; Ludgate M; Libert F; Gerard C; Dumont J E; Vassart G; Parmentier M
Stable expression of the human TSH receptor in CHO cells and characterization of differentially expressing clones.
Biochemical and biophysical research communications 1990;171(3):1044-50.
1990: Streydio C; Swillens S; Georges M; Szpirer C; Vassart G
Structure, evolution and chromosomal localization of the human pregnancy-specific beta 1-glycoprotein gene family.
Genomics 1990;7(4):661-2.
1990: Ledent C; Parmentier M; Vassart G
Tissue-specific expression and methylation of a thyroglobulin-chloramphenicol acetyltransferase fusion gene in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(16):6176-80.
1990: Gérard C; Christophe D; Compère T; Vassart G
The poly (purine) poly (pyrimidine) sequence in the 5' end of the thyroglobulin gene used as a probe, identifies a DNA fingerprint in man.
Nucleic acids research 1990;18(14):4297.
1990: Donner C; Simon P; Gosselin F; Vermeylen D; Avni F; Liesnard C; Vamos E; Cochaux P; Vassart G; Rodesch F
[Cordocentesis: experience in 391 initial samples]
Revue médicale de Bruxelles 1990;11(6):217-22.
1990: Cochaux P; Velu T; Abramowicz M; Vassart G
[Molecular and diagnostic genetics]
Revue médicale de Bruxelles 1990;11(6):188-94.
1990: Schiffmann S N; Libert F; Vassart G; Dumont J E; Vanderhaeghen J J
A cloned G protein-coupled protein with a distribution restricted to striatal medium-sized neurons. Possible relationship with D1 dopamine receptor.
Brain research 1990;519(1-2):333-7.
1990: Donner C; Simon P; Gosselin F; Vamos E; Cochaux P; Vassart G; Rodesch F
[Chorionic villi sampling: experience of the initial 500 samples]
Revue médicale de Bruxelles 1990;11(6):211-5.
1990: Streydio C; Swillens S; Georges M; Szpirer C; Vassart G
Structure, evolution and chromosomal localization of the human pregnancy-specific beta 1 glycoprotein gene family.
Genomics 1990;6(4):579-92.
1990: Libert F; Parmentier M; Lefort A; Dumont J E; Vassart G
Complete nucleotide sequence of a putative G protein coupled receptor: RDC1.
Nucleic acids research 1990;18(7):1917.
1990: Libert F; Parmentier M; Lefort A; Dumont J E; Vassart G
Complete nucleotide sequence of a putative G protein coupled receptor: RDC4.
Nucleic acids research 1990;18(7):1916.
1990: Libert F; Parmentier M; Lefort A; Dumont J E; Vassart G
Complete nucleotide sequence of a putative G protein coupled receptor: RDC7.
Nucleic acids research 1990;18(7):1915.
1990: Libert F; Parmentier M; Lefort A; Dumont J E; Vassart G
Complete nucleotide sequence of a putative G protein coupled receptor: RDC8.
Nucleic acids research 1990;18(7):1914.
1990: Javaux F; Vassart G; Christophe D
Nucleotide sequence of a putative transcription factor recognizing the thyroglobulin promoter.
Nucleic acids research 1990;18(5):1301.
1990: Perret J; Shia Y C; Fries R; Vassart G; Georges M
A polymorphic satellite sequence maps to the pericentric region of the bovine Y chromosome.
Genomics 1990;6(3):482-90.
1990: Georges M; Lathrop M; Hilbert P; Marcotte A; Schwers A; Swillens S; Vassart G; Hanset R
On the use of DNA fingerprints for linkage studies in cattle.
Genomics 1990;6(3):461-74.
1990: Vassart G; Cochaux P; Abramowicz M
CF screening.
Nature 1990;343(6259):586.
1990: Streydio C; Vassart G
Expression of human pregnancy specific beta 1 glycoprotein (PSG) genes during placental development.
Biochemical and biophysical research communications 1990;166(3):1265-73.
1990: Abramowicz M J; Vassart G; Christophe D
Thyroid peroxidase gene promoter confers TSH responsiveness to heterologous reporter genes in transfection experiments.
Biochemical and biophysical research communications 1990;166(3):1257-64.
1990: Libert F; Parmentier M; Maenhaut C; Lefort A; Gérard C; Perret J; Van Sande J; Dumont J E; Vassart G
Molecular cloning of a dog thyrotropin (TSH) receptor variant.
Molecular and cellular endocrinology 1990;68(1):R15-7.
1990: Georges M; Lathrop M; Bouquet Y; Hilbert P; Marcotte A; Schwers A; Roupain J; Vassart G; Hanset R
Linkage relationships among 20 genetic markers in cattle. Evidence for linkage between two pairs of blood group systems: B-Z and S-F/V respectively.
Animal genetics 1990;21(2):95-105.
1990: Lefort A; Passage E; Libert F; Szpirer J; Vassart G; Mattei M G
Localization of human calcyphosine gene (CAPS) to the p13.3 region of chromosome 19 by in situ hybridization.
Cytogenetics and cell genetics 1990;54(3-4):154-5.
1990: Libert F; Passage E; Lefort A; Vassart G; Mattei M G
Localization of human thyrotropin receptor gene to chromosome region 14q3 by in situ hybridization.
Cytogenetics and cell genetics 1990;54(1-2):82-3.
1990: Gérard C M; Lefort A; Christophe D; Libert F; Van Sande J; Dumont J E; Vassart G
Distinct transcriptional effects of cAMP on 2 thyroid specific genes: thyroperoxidase and thyroglobulin.
Hormone and metabolic research. Supplement series 1990;23():38-43.
1990: Ludgate M; Vassart G
The molecular genetics of three thyroid autoantigens: thyroglobulin, thyroid peroxidase and the thyrotropin receptor.
Autoimmunity 1990;7(2-3):201-11.
1989: Libert F; Lefort A; Gerard C; Parmentier M; Perret J; Ludgate M; Dumont J E; Vassart G
Cloning, sequencing and expression of the human thyrotropin (TSH) receptor: evidence for binding of autoantibodies.
Biochemical and biophysical research communications 1989;165(3):1250-5.
1989: Parmentier M; Libert F; Maenhaut C; Lefort A; Gérard C; Perret J; Van Sande J; Dumont J E; Vassart G
Nucleotide sequence of the dog thyrotropin receptor cDNA.
Nucleic acids research 1989;17(24):10493.
1989: Gérard C M; Lefort A; Christophe D; Libert F; Van Sande J; Dumont J E; Vassart G
Control of thyroperoxidase and thyroglobulin transcription by cAMP: evidence for distinct regulatory mechanisms.
Molecular endocrinology (Baltimore, Md.) 1989;3(12):2110-8.
1989: Parmentier M; Libert F; Maenhaut C; Lefort A; Gérard C; Perret J; Van Sande J; Dumont J E; Vassart G
Molecular cloning of the thyrotropin receptor.
Science (New York, N.Y.) 1989;246(4937):1620-2.
1989: Dong Q; Ludgate M; Vassart G
Towards an antigenic map of human thyroglobulin: identification of ten epitope-bearing sequences within the primary structure of thyroglobulin.
The Journal of endocrinology 1989;122(1):169-76.
1989: Christophe D; Gérard C; Juvenal G; Bacolla A; Teugels E; Ledent C; Christophe-Hobertus C; Dumont J E; Vassart G
Identification of a cAMP-responsive region in thyroglobulin gene promoter.
Molecular and cellular endocrinology 1989;64(1):5-18.
1989: Ludgate M; Mariotti S; Libert F; Dinsart C; Piccolo P; Santini F; Ruf J; Pinchera A; Vassart G
Antibodies to human thyroid peroxidase in autoimmune thyroid disease: studies with a cloned recombinant complementary deoxyribonucleic acid epitope.
The Journal of clinical endocrinology and metabolism 1989;68(6):1091-6.
1989: Libert F; Parmentier M; Lefort A; Dinsart C; Van Sande J; Maenhaut C; Simons M J; Dumont J E; Vassart G
Selective amplification and cloning of four new members of the G protein-coupled receptor family.
Science (New York, N.Y.) 1989;244(4904):569-72.
1989: Bikker H; Bolhuis P A; Vassart G; Libert F; Massaro G; de Vijlder J J
Eco RI RFLP in the human thyroid peroxidase (TPO) gene on chromosome 2.
Human genetics 1989;82(1):95.
1989: Hansen C; Javaux F; Juvenal G; Vassart G; Christophe D
cAMP-dependent binding of a trans-acting factor to the thyroglobulin promoter.
Biochemical and biophysical research communications 1989;160(2):722-31.
1989: Massaro G; Libert F; Vassart G; Dinsart C
RFLPs detected at 2 pter-p12 with a thyroid peroxidase cDNA probe, TPO3 (McKusick no. 27450).
Nucleic acids research 1989;17(5):2155.
1989: Mercken L; Simons M J; Brocas H; Vassart G
Alternative splicing may be responsible for heterogeneity of thyroglobulin structure.
Biochimie 1989;71(2):223-6.
1989: Lefort A; Lecocq R; Libert F; Lamy F; Swillens S; Vassart G; Dumont J E
Cloning and sequencing of a calcium-binding protein regulated by cyclic AMP in the thyroid.
The EMBO journal 1989;8(1):111-6.
1989: Hilbert P; Marcotte A; Schwers A; Hanset R; Vassart G; Georges M
Analysis of genetic variation in the Belgian Blue cattle breed using DNA sequence polymorphism at the growth hormone, low density lipoprotein receptor, alpha-subunit of glycoprotein hormones and thyroglobulin loci.
Animal genetics 1989;20(4):383-93.
1988: Gerard C M; Lefort A; Libert F; Christophe D; Dumont J E; Vassart G
Transcriptional regulation of the thyroperoxydase gene by thyrotropin and forskolin.
Molecular and cellular endocrinology 1988;60(2-3):239-42.
1988: Hansen C; Gerard C; Vassart G; Stordeur P; Christophe D
Thyroid-specific and cAMP-dependent hypersensitive regions in thyroglobulin gene chromatin.
European journal of biochemistry / FEBS 1988;178(2):387-93.
1988: Georges M; Hilbert P; Lequarré A S; Leclerc V; Hanset R; Vassart G
Use of DNA bar codes to resolve a canine paternity dispute.
Journal of the American Veterinary Medical Association 1988;193(9):1095-8.
1988: Parmentier M; Vassart G
HindIII RFLP on chromosome 8 detected with a calbindin 27 kDa cDNA probe, HBSC21.
Nucleic acids research 1988;16(19):9373.
1988: Streydio C; Lacka K; Swillens S; Vassart G
The human pregnancy-specific beta 1-glycoprotein (PS beta G) and the carcinoembryonic antigen (CEA)-related proteins are members of the same multigene family.
Biochemical and biophysical research communications 1988;154(1):130-7.
1988: Simon P; Brocas H; Baran D; van Geffel R; Rodesch F; Vassart G
Carrier prediction of cystic fibrosis in 36 families by means of restriction fragment length polymorphism.
European journal of pediatrics 1988;147(2):199-201.
1988: de Vijlder J J; Dinsart C; Libert F; Geurts van Kessel A; Bikker H; Bolhuis P A; Vassart G
Regional localization of the gene for thyroid peroxidase to human chromosome 2pter----p12.
Cytogenetics and cell genetics 1988;47(3):170-2.
1988: Georges M; Lequarré A S; Castelli M; Hanset R; Vassart G
DNA fingerprinting in domestic animals using four different minisatellite probes.
Cytogenetics and cell genetics 1988;47(3):127-31.
1987: Parmentier M; Lawson D E; Vassart G
Human 27-kDa calbindin complementary DNA sequence. Evolutionary and functional implications.
European journal of biochemistry / FEBS 1987;170(1-2):207-15.
1987: Libert F; Ruel J; Ludgate M; Swillens S; Alexander N; Vassart G; Dinsart C
Thyroperoxidase, an auto-antigen with a mosaic structure made of nuclear and mitochondrial gene modules.
The EMBO journal 1987;6(13):4193-6.
1987: Georges M; Cochaux P; Lequarre A S; Young M W; Vassart G
DNA fingerprinting in man using a mouse probe related to part of the Drosophila 'Per' gene.
Nucleic acids research 1987;15(17):7193.
1987: Parma J; Christophe D; Pohl V; Vassart G
Structural organization of the 5' region of the thyroglobulin gene. Evidence for intron loss and "exonization" during evolution.
Journal of molecular biology 1987;196(4):769-79.
1987: Libert F; Ruel J; Ludgate M; Swillens S; Alexander N; Vassart G; Dinsart C
Complete nucleotide sequence of the human thyroperoxidase-microsomal antigen cDNA.
Nucleic acids research 1987;15(16):6735.
1987: Ricketts M H; Simons M J; Parma J; Mercken L; Dong Q; Vassart G
A nonsense mutation causes hereditary goitre in the Afrikander cattle and unmasks alternative splicing of thyroglobulin transcripts.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(10):3181-4.
1987: de Martynoff G; Pohl V; Mercken L; van Ommen G J; Vassart G
Structural organization of the bovine thyroglobulin gene and of its 5'-flanking region.
European journal of biochemistry / FEBS 1987;164(3):591-9.
1987: Vassart G; Georges M; Monsieur R; Brocas H; Lequarre A S; Christophe D
A sequence in M13 phage detects hypervariable minisatellites in human and animal DNA.
Science (New York, N.Y.) 1987;235(4789):683-4.
1987: Vassart G; Brocas H; Christophe D; de Martynoff G; Gérard C; Hansen C; Juvenal G; Ludgate M; Mercken L; Parma J
Normal and defective expression of the thyroglobulin gene.
Hormone research 1987;26(1-4):8-11.
1987: Brocas H; Georges M; Christophe D; Monsieur R; Lequarre A S; Vassart G
[A family of hypervariable minisatellites detected by means of a sequence derived from phage M 13]
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1987;304(3):67-9.
1987: Georges M; Lequarré A S; Hanset R; Vassart G
Genetic variation of the bovine thyroglobulin gene studied at the DNA level.
Animal genetics 1987;18(1):41-50.
1986: Cabrer B; Brocas H; Perez-Castillo A; Pohl V; Navas J J; Targovnik H; Centenera J A; Vassart G
Normal level of thyroglobulin messenger ribonucleic acid in a human congenital goiter with thyroglobulin deficiency.
The Journal of clinical endocrinology and metabolism 1986;63(4):931-40.
1986: Ludgate M; Swillens S; Mercken L; Vassart G
Homology between thyroglobulin and acetylcholinesterase: an explanation for pathogenesis of Graves' ophthalmopathy?
Lancet 1986;2(8500):219-20.
1986: Swillens S; Ludgate M; Mercken L; Dumont J E; Vassart G
Analysis of sequence and structure homologies between thyroglobulin and acetylcholinesterase: possible functional and clinical significance.
Biochemical and biophysical research communications 1986;137(1):142-8.
1985: Van Heuverswyn B; Leriche A; Van Sande J; Dumont J E; Vassart G
Transcriptional control of thyroglobulin gene expression by cyclic AMP.
FEBS letters 1985;188(2):192-6.
1985: Mercken L; Simons M J; Swillens S; Massaer M; Vassart G
Primary structure of bovine thyroglobulin deduced from the sequence of its 8,431-base complementary DNA.
Nature 1985;316(6029):647-51.
1985: Rabin M; Barker P E; Ruddle F H; Brocas H; Targovnik H; Vassart G
Proximity of thyroglobulin and c-myc genes on human chromosome 8.
Somatic cell and molecular genetics 1985;11(4):397-402.
1985: Christophe D; Cabrer B; Bacolla A; Targovnik H; Pohl V; Vassart G
An unusually long poly(purine)-poly(pyrimidine) sequence is located upstream from the human thyroglobulin gene.
Nucleic acids research 1985;13(14):5127-44.
1985: Vassart G; Bacolla A; Brocas H; Christophe D; de Martynoff G; Leriche A; Mercken L; Parma J; Pohl V; Targovnik H
Structure, expression and regulation of the thyroglobulin gene.
Molecular and cellular endocrinology 1985;40(2-3):89-97.
1985: Ricketts M H; Pohl V; de Martynoff G; Boyd C D; Bester A J; Van Jaarsveld P P; Vassart G
Defective splicing of thyroglobulin gene transcripts in the congenital goitre of the Afrikander cattle.
The EMBO journal 1985;4(3):731-7.
1985: Mercken L; Simons M J; De Martynoff G; Swillens S; Vassart G
Presence of hormonogenic and repetitive domains in the first 930 amino acids of bovine thyroglobulin as deduced from the cDNA sequence.
European journal of biochemistry / FEBS 1985;147(1):59-64.
1984: Mercken L; Massaer M; Simons M J; Swillens S; Vassart G
Identification of hormonogenic domains in the carboxyl terminal region of bovine thyroglobulin.
Biochemical and biophysical research communications 1984;125(3):961-6.
1984: Van Heuverswyn B; Streydio C; Brocas H; Refetoff S; Dumont J; Vassart G
Thyrotropin controls transcription of the thyroglobulin gene.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(19):5941-5.
1984: Targovnik H M; Pohl V; Christophe D; Cabrer B; Brocas H; Vassart G
Structural organization of the 5' region of the human thyroglobulin gene.
European journal of biochemistry / FEBS 1984;141(2):271-7.
1982: Mercken L; Simons M J; Vassart G
The 5'-end of bovine thyroglobulin mRNA encodes a hormonogenic peptide.
FEBS letters 1982;149(2):285-7.
1982: Vassart G; Brocas H; Christophe D; de Martynoff G; Leriche A; Mercken L; Pohl V; Van Heuverswyn B
[Structure and expression of thyroglobulin gene]
Annales d'endocrinologie 1982;43(5):404-14.
1982: Christophe D; Pohl V; Van Heuverswijn B; De Martynoff G; Brocas H; Dumont J E; Pasteels J L; Vassart G
Isolation and characterization of a fragment of rat thyroglobulin gene.
Biochemical and biophysical research communications 1982;105(3):1166-75.
1982: Christophe D; Mercken L; Brocas H; Pohl V; Vassart G
Molecular cloning of the 8000-base thyroglobulin structural gene.
European journal of biochemistry / FEBS 1982;122(3):461-9.
1982: Brocas H; Christophe D; Pohl V; Vassart G
Cloning of human thyroglobulin complementary DNA.
FEBS letters 1982;137(2):189-92.
1981: de Vijlder J J; van Ommen G J; van Voorthuizen W F; Koch C A; Arnberg A C; Vassart G; Dinsart C; Flavell R A
Nonfunctional thyroglobulin messenger RNA in goats with hereditary congenital goiter.
Journal of molecular and applied genetics 1981;1(1):51-9.
1980: Christophe D; Brocas H; Gannon F; de Martynoff G; Pays E; Vassart G
Molecular cloning of bovine thyroglobulin complementary DNA. Characterization of 2500-base-pair and 1900-base-pair fragments.
European journal of biochemistry / FEBS 1980;111(2):419-23.
1980: Brocas H; Christophe D; Van Heuverswijn B; Scherberg N; Vassart G
Molecular cloning of Pst I fragments from rat double stranded thyroglobulin complementary DNA.
Biochemical and biophysical research communications 1980;96(4):1785-92.
1980: de Martynoff G; Pays E; Vassart G
Synthesis of a full length DNA complementary to thyroglobulin 33 S messenger RNA.
Biochemical and biophysical research communications 1980;93(3):645-53.
1980: Van Herle A J; Van Heuverswyn B; Vassart G
[Dosage of serum thyroglobulin in clinical practice (author's transl)]
Revue médicale de Bruxelles 1980;1(1):5-8.

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