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Gilbert Vassart

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Patricia Olivier; Jasmine Parma; Hervé Sartelet; Judith Simoneau-Roy; Diane Francoeur; Gilbert Vassart; Guy Van Vliet
Leydig cell tumors in children: contrasting clinical, hormonal, anatomical, and molecular characteristics in boys and girls.
Frederic Vandergheynst; Gilbert Vassart; Ingrid Beukinga; Anne Kornreich; Olivier Pradier; Guy Decaux
Lack of responsiveness to 1-desamino-D arginin vasopressin (desmopressin) in male patients with nephrogenic syndrome of inappropriate antidiuresis: from bench to bedside.
Maxime Zoenen; Stéphane Swillens; Eneko Urizar; Gilbert Vassart; Sabine Costagliola
Evidence for activity-regulated hormone-binding cooperativity across glycoprotein hormone receptor homomers.

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2012: Patricia Olivier; Jasmine Parma; Hervé Sartelet; Judith Simoneau-Roy; Diane Francoeur; Gilbert Vassart; Guy Van Vliet
Leydig cell tumors in children: contrasting clinical, hormonal, anatomical, and molecular characteristics in boys and girls.
The Journal of pediatrics 2012;161(6):1147-52.
2012: Frederic Vandergheynst; Gilbert Vassart; Ingrid Beukinga; Anne Kornreich; Olivier Pradier; Guy Decaux
Lack of responsiveness to 1-desamino-D arginin vasopressin (desmopressin) in male patients with nephrogenic syndrome of inappropriate antidiuresis: from bench to bedside.
European journal of clinical investigation 2012;42(3):254-9.
2012: Maxime Zoenen; Stéphane Swillens; Eneko Urizar; Gilbert Vassart; Sabine Costagliola
Evidence for activity-regulated hormone-binding cooperativity across glycoprotein hormone receptor homomers.
Nature communications 2012;3():1007.
2011: Elena Livadariu; Sylvie Maweja; Catherine Rydlewski; Anne S Thonnard; Silvia Vandeva; Gilbert Vassart; Daniela Betea; Maria C Burlacu; Adrian F Daly; Etienne Hamoir; Renata S Auriemma; Albert Beckers
Mutations of calcium-sensing receptor gene: two novel mutations and overview of impact on calcium homeostasis.
European journal of endocrinology / European Federation of Endocrine Societies 2011;165(2):353-8.
2011: Roxana C Mustata; Tom Van Loy; Anne Lefort; Frédérick Libert; Sandra Strollo; Gilbert Vassart; Marie-Isabelle Garcia
Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo.
EMBO reports 2011;12(6):558-64.
2011: Gilbert Vassart; Sabine Costagliola
G protein-coupled receptors: mutations and endocrine diseases.
Nature reviews. Endocrinology 2011;7(6):362-72.
2010: Sophie Stoppa-Vaucher; Annie Lapointe; Sophie Turpin; Catherine Rydlewski; Gilbert Vassart; Johnny Deladoëy
Ectopic thyroid gland causing dysphonia: imaging and molecular studies.
The Journal of clinical endocrinology and metabolism 2010;95(10):4509-10.
2010: D Tiotiu; B Alvaro Mercadal; R Imbert; J Verbist; Isabelle Demeestere; Anne De Leener; Yvon Englert; Gilbert Vassart; Sabine Costagliola; Anne Delbaere
Variants of the BMP15 gene in a cohort of patients with premature ovarian failure.
Human reproduction (Oxford, England) 2010;25(6):1581-7.
2010: Gilbert Vassart
An in vivo demonstration of functional G protein-coupled receptor dimers.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(5):1819-20.
2010: Rasha Abu-Khudir; Jean Paquette; Anne Lefort; Frederick Libert; Jean-Pierre Chanoine; Gilbert Vassart; Johnny Deladoëy
Transcriptome, methylome and genomic variations analysis of ectopic thyroid glands.
PloS one 2010;5(10):e13420.
2009: Marie-Isabelle Garcia; Mariangela Ghiani; Anne Lefort; Frédérick Libert; Sandra Strollo; Gilbert Vassart
LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine.
Developmental biology 2009;331(1):58-67.
2009: Gilbert Vassart
Omissions and misquotations: rewriting history.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2009;15(4):383-4; author reply 384-5.
2009: Marie-Alexandra H Lambot; Fernando Mendive; Patrick Laurent; Gregory Van Schoore; Jean-Christophe Noël; Pierre Vanderhaeghen; Gilbert Vassart
Three-dimensional reconstruction of efferent ducts in wild-type and Lgr4 knock-out mice.
Anatomical record (Hoboken, N.J. : 2007) 2009;292(4):595-603.
2009: Guy Van Vliet; Gilbert Vassart
Monozygotic twins are generally discordant for congenital hypothyroidism from thyroid dysgenesis.
Hormone research 2009;72(5):320.
2009: Olga Valverde; CELERIER Evelyne; Mária Baranyi; Pierre Vanderhaeghen; Rafael Maldonado; Beata Sperlagh; Gilbert Vassart; Catherine Ledent
GPR3 receptor, a novel actor in the emotional-like responses.
PloS one 2009;4(3):e4704.
2009: Emilie Maquet; Sabine Costagliola; Jasmine Parma; Christiane Christophe-Hobertus; Luc L Oligny; Jean-Christophe Fournet; Yves Robitaille; Jean-Marc Vuissoz; Antoine Payot; Sophie Laberge; Gilbert Vassart; Guy Van Vliet; Johnny Deladoëy
Lethal respiratory failure and mild primary hypothyroidism in a term girl with a de novo heterozygous mutation in the TITF1/NKX2.1 gene.
The Journal of clinical endocrinology and metabolism 2009;94(1):197-203.
2008: E Gonzalez-Merino; Serena Emiliani; B Pichon; Jasmine Parma; Anne-Sophie Vannin; Anne Delbaere; Gilbert Vassart; Marc Abramowicz; Yvon Englert
[Preimplantation genetic diagnosis (PGD): the Erasme Hospital experience].
Revue médicale de Bruxelles 2008;29(6):527-34.
2008: Sema Akcurin; Doga Turkkahraman; Carolyn Tysoe; Sian Ellard; Anne De Leener; Gilbert Vassart; Sabine Costagliola
A family with a novel TSH receptor activating germline mutation (p.Ala485Val).
European journal of pediatrics 2008;167(11):1231-7.
2008: Aravind Raj Sanjeevaiah; Gilbert Vassart; Sri S Srikanta
Follicle-stimulating hormone receptor DNA sequencing: investigation into possible glycoprotein receptor mutation in Van Wyk-Grumbach syndrome.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2008;14(5):648.
2008: Guy Decaux; Alain Soupart; Gilbert Vassart
Non-peptide arginine-vasopressin antagonists: the vaptans.
Lancet 2008;371(9624):1624-32.
2008: Johnny Deladoëy; Nicole Pfarr; Jean-Marc Vuissoz; Jasmine Parma; Gilbert Vassart; Stefan Biesterfeld; Joachim Pohlenz; Guy Van Vliet
Pseudodominant inheritance of goitrous congenital hypothyroidism caused by TPO mutations: molecular and in silico studies.
The Journal of clinical endocrinology and metabolism 2008;93(2):627-33.
2008: J H Duncan Bassett; Allan J Williams; Elaine Murphy; Alan Boyde; Peter G T Howell; Rowan Swinhoe; Marta Archanco; Frédéric Flamant; Jacques Samarut; Sabine Costagliola; Gilbert Vassart; Roy E Weiss; Samuel Refetoff; Graham R Williams
A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism.
Molecular endocrinology (Baltimore, Md.) 2008;22(2):501-12.
2008: Anne De Leener; Gianluigi Caltabiano; Sanly Erkan; Mehmet Idil; Gilbert Vassart; Leonardo Pardo; Sabine Costagliola
Identification of the first germline mutation in the extracellular domain of the follitropin receptor responsible for spontaneous ovarian hyperstimulation syndrome.
Human mutation 2008;29(1):91-8.
2008: Tom Van Loy; Hans Peter Vandersmissen; Matthias B Van Hiel; Jeroen Poels; Heleen Verlinden; Liesbeth Badisco; Gilbert Vassart; Jozef Vanden Broeck
Comparative genomics of leucine-rich repeats containing G protein-coupled receptors and their ligands.
General and comparative endocrinology 2008;155(1):14-21.
2007: Stéphane Mievis; Marc Levivier; Gilbert Vassart; Jacques Brotchi; Catherine Ledent; David Blum
Citicoline is not protective in experimental models of Huntington's disease.
Neurobiology of aging 2007;28(12):1944-6.
2007: Jean-Yves Springael; Eneko Urizar; Sabine Costagliola; Gilbert Vassart; Marc Parmentier
Allosteric properties of G protein-coupled receptor oligomers.
Pharmacology & therapeutics 2007;115(3):410-8.
2007: Tom Van Loy; Matthias B Van Hiel; Hans Peter Vandersmissen; Jeroen Poels; Fernando Mendive; Gilbert Vassart; Jozef Vanden Broeck
Evolutionary conservation of bursicon in the animal kingdom.
General and comparative endocrinology 2007;153(1-3):59-63.
2007: Barbara Dessars; Linda E De Raeve; Hakim El Housni; Catherine J Debouck; Pierre J Sidon; Renato Morandini; Diane Roseeuw; Ghanem Ghanem; Gilbert Vassart; Pierre Heimann
Chromosomal translocations as a mechanism of BRAF activation in two cases of large congenital melanocytic nevi.
The Journal of investigative dermatology 2007;127(6):1468-70.
2007: Guy Decaux; Frédéric Vandergheynst; Yasmina Bouko; Jasmine Parma; Gilbert Vassart; Catheline Vilain
Nephrogenic syndrome of inappropriate antidiuresis in adults: high phenotypic variability in men and women from a large pedigree.
Journal of the American Society of Nephrology : JASN 2007;18(2):606-12.
2007: Johnny Deladoëy; Gilbert Vassart; Guy Van Vliet
Possible non-Mendelian mechanisms of thyroid dysgenesis.
Endocrine development 2007;10():29-42.
2007: Stéphane Mievis; Marc Levivier; David Communi; Gilbert Vassart; Jacques Brotchi; Catherine Ledent; David Blum
Lack of minocycline efficiency in genetic models of Huntington's disease.
Neuromolecular medicine 2007;9(1):47-54.
2006: Marco Bonomi; Marta Busnelli; Luca Persani; Gilbert Vassart; Sabine Costagliola
Structural differences in the hinge region of the glycoprotein hormone receptors: evidence from the sulfated tyrosine residues.
Molecular endocrinology (Baltimore, Md.) 2006;20(12):3351-63.
2006: Anne Delbaere; Guillaume Smits; Gilbert Vassart; Sabine Costagliola
Genetic predictors of ovarian hyperstimulation syndrome in women undergoing in vitro fertilization.
Nature clinical practice. Endocrinology & metabolism 2006;2(11):590-1.
2006: Joost Van Durme; Florence Horn; Sabine Costagliola; Gert Vriend; Gilbert Vassart
GRIS: glycoprotein-hormone receptor information system.
Molecular endocrinology (Baltimore, Md.) 2006;20(9):2247-55.
2006: Jean-Yves Springael; Phu Nguyen Le Minh; Eneko Urizar; Sabine Costagliola; Gilbert Vassart; Marc Parmentier
Allosteric modulation of binding properties between units of chemokine receptor homo- and hetero-oligomers.
Molecular pharmacology 2006;69(5):1652-61.
2006: Fernando Mendive; Patrick Laurent; Grégory Van Schoore; William Skarnes; Roland Pochet; Gilbert Vassart
Defective postnatal development of the male reproductive tract in LGR4 knockout mice.
Developmental biology 2006;290(2):421-34.
2006: Anne De Leener; Lucia Montanelli; Joost Van Durme; Heedong Chae; Guillaume Smits; Gilbert Vassart; Sabine Costagliola
Presence and absence of follicle-stimulating hormone receptor mutations provide some insights into spontaneous ovarian hyperstimulation syndrome physiopathology.
The Journal of clinical endocrinology and metabolism 2006;91(2):555-62.
2005: Patrick Laurent; Jerome Becker; Olga Valverde; Catherine Ledent; Alban de Kerchove D'Exaerde; Serge N Schiffmann; Rafael Maldonado; Gilbert Vassart; Marc Parmentier
The prolactin-releasing peptide antagonizes the opioid system through its receptor GPR10.
Nature neuroscience 2005;8(12):1735-41.
2005: Gilbert Vassart; Jacques E Dumont
Thyroid dysgenesis: multigenic or epigenetic ... or both?
Endocrinology 2005;146(12):5035-7.
2005: Helmut Grasberger; Martine Vaxillaire; Silvana Pannain; John C Beck; Aviva Mimouni-Bloch; Vincent Vatin; Gilbert Vassart; philippe froguel; Samuel Refetoff
Identification of a locus for nongoitrous congenital hypothyroidism on chromosome 15q25.3-26.1.
Human genetics 2005;118(3-4):348-55.
2005: Sabine Costagliola; Eneko Urizar; Fernando Mendive; Gilbert Vassart
Specificity and promiscuity of gonadotropin receptors.
Reproduction (Cambridge, England) 2005;130(3):275-81.
2005: Grégory Van Schoore; Fernando Mendive; Roland Pochet; Gilbert Vassart
Expression pattern of the orphan receptor LGR4/GPR48 gene in the mouse.
Histochemistry and cell biology 2005;124(1):35-50.
2005: Gilbert Vassart; Jozef Vanden Broeck; Fernando Mendive; Tom Van Loy
The parable of the mandarin.
EMBO reports 2005;6(7):592.
2005: Valérie Wittamer; Benjamin Bondue; Aude Guillabert; Gilbert Vassart; Marc Parmentier; David Communi
Neutrophil-mediated maturation of chemerin: a link between innate and adaptive immunity.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(1):487-93.
2005: Helmut Grasberger; Aviva Mimouni-Bloch; Marie-Christine Vantyghem; Guy Van Vliet; Marc J Abramowicz; Daniel L Metzger; Hussein Abdullatif; Catherine Rydlewski; Paolo Emidio Macchia; Neal H Scherberg; Jacqueline Van Sande; Marc Mimouni; Roy E Weiss; Gilbert Vassart; Samuel Refetoff
Autosomal dominant resistance to thyrotropin as a distinct entity in five multigenerational kindreds: clinical characterization and exclusion of candidate loci.
The Journal of clinical endocrinology and metabolism 2005;90(7):4025-34.
2005: Helmut Grasberger; Usanee Ringkananont; Paule Lefrancois; Marc J Abramowicz; Gilbert Vassart; Samuel Refetoff
Thyroid transcription factor 1 rescues PAX8/p300 synergism impaired by a natural PAX8 paired domain mutation with dominant negative activity.
Molecular endocrinology (Baltimore, Md.) 2005;19(7):1779-91.
2005: Catherine Ledent; Isabelle Demeestere; David Blum; Julien Petermans; Tuula Hämäläinen; Guillaume Smits; Gilbert Vassart
Premature ovarian aging in mice deficient for Gpr3.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(25):8922-6.
2005: Eneko Urizar; Lucia Montanelli; Tiffany Loy; Marco Bonomi; Stéphane Swillens; Celine Gales; Michel Bouvier; Guillaume Smits; Gilbert Vassart; Sabine Costagliola
Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity.
The EMBO journal 2005;24(11):1954-64.
2005: Bernard Lagane; Sébastien Ballet; Thierry Planchenault; Karl Balabanian; Emmanuel Le Poul; Cédric Blanpain; Yann Percherancier; Isabelle Staropoli; Gilbert Vassart; Martin Oppermann; Marc Parmentier; Françoise Bachelerie
Mutation of the DRY motif reveals different structural requirements for the CC chemokine receptor 5-mediated signaling and receptor endocytosis.
Molecular pharmacology 2005;67(6):1966-76.
2005: Eneko Urizar; Sylvie Claeysen; Xavier Deupí; Cédric Govaerts; Sabine Costagliola; Gilbert Vassart; Leonardo Pardo
An activation switch in the rhodopsin family of G protein-coupled receptors: the thyrotropin receptor.
The Journal of biological chemistry 2005;280(17):17135-41.
2005: Fernando Mendive; Tom Van Loy; Sylvie Claeysen; Jeroen Poels; Michael Williamson; Frank Hauser; Cornelis J P Grimmelikhuijzen; Gilbert Vassart; Jozef Vanden Broeck
Drosophila molting neurohormone bursicon is a heterodimer and the natural agonist of the orphan receptor DLGR2.
FEBS letters 2005;579(10):2171-6.
2005: Anne Delbaere; Guillaume Smits; Anne De Leener; Sabine Costagliola; Gilbert Vassart
Understanding ovarian hyperstimulation syndrome.
Endocrine 2005;26(3):285-90.
2005: Laïla El-Asmar; Jean-Yves Springael; Sébastien Ballet; Eneko Urizar Andrieu; Gilbert Vassart; Marc Parmentier
Evidence for negative binding cooperativity within CCR5-CCR2b heterodimers.
Molecular pharmacology 2005;67(2):460-9.
2005: Jerome Becker; Jean-François Mirjolet; Jérôme Bernard; Emmanuel Burgeon; Marie-Jeanne Simons; Gilbert Vassart; Marc Parmentier; Frédérick Libert
Activation of GPR54 promotes cell cycle arrest and apoptosis of human tumor cells through a specific transcriptional program not shared by other Gq-coupled receptors.
Biochemical and biophysical research communications 2005;326(3):677-86.
2005: Isabelle Migeotte; Elena Riboldi; Jean-Denis Franssen; Françoise Grégoire; Cécile Loison; Valérie Wittamer; Michel detheux; Patrick Robberecht; Sabine Costagliola; Gilbert Vassart; Silvano Sozzani; Marc Parmentier; David Communi
Identification and characterization of an endogenous chemotactic ligand specific for FPRL2.
The Journal of experimental medicine 2005;201(1):83-93.
2004: Caroline Daelemans; Guillaume Smits; Viviane de Maertelaer; Sabine Costagliola; Yvon Englert; Gilbert Vassart; Anne Delbaere
Prediction of severity of symptoms in iatrogenic ovarian hyperstimulation syndrome by follicle-stimulating hormone receptor Ser680Asn polymorphism.
The Journal of clinical endocrinology and metabolism 2004;89(12):6310-5.
2004: Sabine Costagliola; Marco Bonomi; Nils G. Morgenthaler; Joost Van Durme; Valérie Panneels; Samuel Refetoff; Gilbert Vassart
Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity.
Molecular endocrinology (Baltimore, Md.) 2004;18(12):3020-34.
2004: Laurent Meeus; Brigitte Gilbert; Catherine Rydlewski; Jasmine Parma; Anne Lienhardt Roussie; Marc J Abramowicz; Catheline Vilain; Daniel Christophe; Sabine Costagliola; Gilbert Vassart
Characterization of a novel loss of function mutation of PAX8 in a familial case of congenital hypothyroidism with in-place, normal-sized thyroid.
The Journal of clinical endocrinology and metabolism 2004;89(9):4285-91.
2004: Lucia Montanelli; Joost Van Durme; Guillaume Smits; Marco Bonomi; Patrice Rodien; Eric J Devor; Kristin A Moffat-Wilson; Leonardo Pardo; Gilbert Vassart; Sabine Costagliola
Modulation of ligand selectivity associated with activation of the transmembrane region of the human follitropin receptor.
Molecular endocrinology (Baltimore, Md.) 2004;18(8):2061-73.
2004: Jeroen Poels; Tom Van Loy; Vanessa Franssens; Michel detheux; Ronald J Nachman; Hendrica B Oonk; Karl E O Akerman; Gilbert Vassart; Marc Parmentier; Arnold De Loof; Herbert Torfs; Jozef Vanden Broeck
Substitution of conserved glycine residue by alanine in natural and synthetic neuropeptide ligands causes partial agonism at the stomoxytachykinin receptor.
Journal of neurochemistry 2004;90(2):472-8.
2004: Lucia Montanelli; Anne Delbaere; Costantino Di Carlo; Carmine Nappi; Guillaume Smits; Gilbert Vassart; Sabine Costagliola
A mutation in the follicle-stimulating hormone receptor as a cause of familial spontaneous ovarian hyperstimulation syndrome.
The Journal of clinical endocrinology and metabolism 2004;89(4):1255-8.
2004: Valérie Wittamer; Françoise Grégoire; Patrick Robberecht; Gilbert Vassart; David Communi; Marc Parmentier
The C-terminal nonapeptide of mature chemerin activates the chemerin receptor with low nanomolar potency.
The Journal of biological chemistry 2004;279(11):9956-62.
2004: Gilbert Vassart; Leonardo Pardo; Sabine Costagliola
A molecular dissection of the glycoprotein hormone receptors.
Trends in biochemical sciences 2004;29(3):119-26.
2004: Lucia Montanelli; Anne Delbaere; Costantino Di Carlo; Carmine Nappi; Guillaume Smits; Gilbert Vassart; Sabine Costagliola
A mutation in the follicle-stimulating hormone receptor as a cause of familial spontaneous ovarian hyperstimulation syndrome.
The Journal of clinical endocrinology and metabolism 2004;89(3):1255-8.
2004: Anne Delbaere; Guillaume Smits; Olufemi Olatunbosun; Roger Pierson; Gilbert Vassart; Sabine Costagliola
New insights into the pathophysiology of ovarian hyperstimulation syndrome. What makes the difference between spontaneous and iatrogenic syndrome?
Human reproduction (Oxford, England) 2004;19(3):486-9.
2004: Gilbert Vassart
Activating mutations of the TSH receptor.
Thyroid : official journal of the American Thyroid Association 2004;14(1):86-7.
2004: Catheline Vilain; Gilbert Vassart
Small amplified RNA-SAGE.
Methods in molecular biology (Clifton, N.J.) 2004;258():135-52.
2004: Gilbert Vassart; Sabine Costagliola
A physiological role for the posttranslational cleavage of the thyrotropin receptor?
Endocrinology 2004;145(1):1-3.
2003: Cédric Blanpain; Emmanuel Le Poul; Jasmine Parma; Christiane Knoop; Michel detheux; Marc Parmentier; Gilbert Vassart; Marc J Abramowicz
Serotonin 5-HT(2B) receptor loss of function mutation in a patient with fenfluramine-associated primary pulmonary hypertension.
Cardiovascular research 2003;60(3):518-28.
2003: Valérie Wittamer; Jean-Denis Franssen; MARISA VULCANO; Jean-François Mirjolet; Emmanuel Le Poul; Isabelle Migeotte; Stéphane Brézillon; Richard Tyldesley; Cédric Blanpain; Michel detheux; Alberto Mantovani; Silvano Sozzani; Gilbert Vassart; Marc Parmentier; David Communi
Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids.
The Journal of experimental medicine 2003;198(7):977-85.
2003: Hakim El Housni; Pierre Heimann; Jasmine Parma; Gilbert Vassart
Single-nucleotide polymorphism genotyping by melting analysis of dual-labeled probes: examples using factor V Leiden and prothrombin 20210A mutations.
Clinical chemistry 2003;49(10):1669-72.
2003: Guillaume Smits; Olufemi Olatunbosun; Anne Delbaere; Roger Pierson; Gilbert Vassart; Sabine Costagliola
Ovarian hyperstimulation syndrome due to a mutation in the follicle-stimulating hormone receptor.
The New England journal of medicine 2003;349(8):760-6.
2003: Emmanuel Le Poul; Cecile Loison; Sofie Struyf; Jean-Yves Springael; Vincent Lannoy; Marie-Eve Decobecq; Stephane Brezillon; Vincent Dupriez; Gilbert Vassart; Jo Van Damme; Marc Parmentier; Michel detheux
Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation.
The Journal of biological chemistry 2003;278(28):25481-9.
2003: Guillaume Smits; Mercedes Campillo; Cédric Govaerts; Véronique Janssens; Christine Richter; Gilbert Vassart; Leonardo Pardo; Sabine Costagliola
Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificity.
The EMBO journal 2003;22(11):2692-703.
2003: Catheline Vilain; Frédérick Libert; David Venet; Sabine Costagliola; Gilbert Vassart
Small amplified RNA-SAGE: an alternative approach to study transcriptome from limiting amount of mRNA.
Nucleic acids research 2003;31(6):e24.
2003: Cédric Blanpain; Benjamin J Doranz; Antoine Bondue; Cédric Govaerts; Anne De Leener; Gilbert Vassart; Robert W Doms; Amanda Proudfoot; Marc Parmentier
The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle.
The Journal of biological chemistry 2003;278(7):5179-87.
2003: Eric Gonzalez-Merino; Serena Emiliani; Gilbert Vassart; Marc Van Den Bergh; Anne-Sophie Vannin; Marc Abramowicz; Danièle Delneste; Yvon Englert
Incidence of chromosomal mosaicism in human embryos at different developmental stages analyzed by fluorescence in situ hybridization.
Genetic testing 2003;7(2):85-95.
2002: Sabine Costagliola; Jean-Denis Franssen; Marco Bonomi; Eneko Urizar; M Willnich; A Bergmann; Gilbert Vassart
Generation of a mouse monoclonal TSH receptor antibody with stimulating activity.
Biochemical and biophysical research communications 2002;299(5):891-6.
2002: Sabine Costagliola; Gilbert Vassart
Monoclonal antibodies with thyroid stimulating activity, at last.
Thyroid : official journal of the American Thyroid Association 2002;12(12):1039-41.
2002: Herbert Torfs; Karl E O Akerman; Ronald J Nachman; Hendrica B Oonk; Michel detheux; Jeroen Poels; Tom Van Loy; Arnold De Loof; Rob H Meloen; Gilbert Vassart; Marc Parmentier; Jozef Vanden Broeck
Functional analysis of synthetic insectatachykinin analogs on recombinant neurokinin receptor expressing cell lines.
Peptides 2002;23(11):1999-2005.
2002: Rebecca Perry; Claudine Heinrichs; Pierre Bourdoux; Khalil Khoury; François Szöts; Jean H Dussault; Gilbert Vassart; Guy Van Vliet
Discordance of monozygotic twins for thyroid dysgenesis: implications for screening and for molecular pathophysiology.
The Journal of clinical endocrinology and metabolism 2002;87(9):4072-7.
2002: Vanessa Vanvooren; S Uchino; Laurence Duprez; Maria José Costa; J Vandekerckhove; Jasmine Parma; Gilbert Vassart; Jacques E Dumont; Jacqueline Van Sande; S Noguchi
Oncogenic mutations in the thyrotropin receptor of autonomously functioning thyroid nodules in the Japanese population.
European journal of endocrinology / European Federation of Endocrine Societies 2002;147(3):287-91.
2002: Herbert Torfs; Michel detheux; Hendrica B Oonk; Karl E O Akerman; Jeroen Poels; Tom Van Loy; Arnold De Loof; Gilbert Vassart; Marc Parmentier; Jozef Vanden Broeck
Analysis of C-terminally substituted tachykinin-like peptide agonists by means of aequorin-based luminescent assays for human and insect neurokinin receptors.
Biochemical pharmacology 2002;63(9):1675-82.
2002: Sylvie Claeysen; Cédric Govaerts; Anne Lefort; Jacqueline Van Sande; Sabine Costagliola; Leonardo Pardo; Gilbert Vassart
A conserved Asn in TM7 of the thyrotropin receptor is a common requirement for activation by both mutations and its natural agonist.
FEBS letters 2002;517(1-3):195-200.
2002: Herbert Torfs; Jeroen Poels; Michel detheux; Vincent Dupriez; Tom Van Loy; Linda Vercammen; Gilbert Vassart; Marc Parmentier; Jozef Vanden Broeck
Recombinant aequorin as a reporter for receptor-mediated changes of intracellular Ca2+ -levels in Drosophila S2 cells.
Invertebrate neuroscience : IN 2002;4(3):119-24.
2002: Virginie Vlaeminck-Guillem; Su-Chin Ho; Patrice Rodien; Gilbert Vassart; Sabine Costagliola
Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist.
Molecular endocrinology (Baltimore, Md.) 2002;16(4):736-46.
2002: Guillaume Smits; Cédric Govaerts; Isabelle Nubourgh; Leonardo Pardo; Gilbert Vassart; Sabine Costagliola
Lysine 183 and glutamic acid 157 of the TSH receptor: two interacting residues with a key role in determining specificity toward TSH and human CG.
Molecular endocrinology (Baltimore, Md.) 2002;16(4):722-35.
2002: Sabine Costagliola; Valérie Panneels; Marco Bonomi; J Koch; Marie-Christine Many; Guillaume Smits; Gilbert Vassart
Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors.
The EMBO journal 2002;21(4):504-13.
2002: Cédric Blanpain; Jean-Marie Vanderwinden; Josef Cihak; Valérie Wittamer; Emmanuel Le Poul; Hassan Issafras; Manfred Stangassinger; Gilbert Vassart; Stefano Marullo; Detlef Schlndorff; Marc Parmentier; Matthias Mack
Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies.
Molecular biology of the cell 2002;13(2):723-37.
2002: Gilbert Vassart; M Abramowicz; Pascale Cochaux; Laurence Duprez; Hakim El Housni; F Hayez; Pierre Heimann; Jasmine Parma; Esther Vamos; Nicole Van Regemorter
[Medical genetics service].
Revue médicale de Bruxelles 2002;23 Suppl 2():63-7.
2002: Cédric Blanpain; Frédérick Libert; Gilbert Vassart; Marc Parmentier
CCR5 and HIV infection.
Receptors & channels 2002;8(1):19-31.
2001: P Bretones; Laurence Duprez; Jasmine Parma; M David; Gilbert Vassart; Patrice Rodien
A familial case of congenital hypothyroidism caused by a homozygous mutation of the thyrotropin receptor gene.
Thyroid : official journal of the American Thyroid Association 2001;11(10):977-80.
2001: Fernando Mendive; Carina M Rivolta; Christian M Moya; Gilbert Vassart; Héctor M Targovnik
Genomic organization of the human thyroglobulin gene: the complete intron-exon structure.
European journal of endocrinology / European Federation of Endocrine Societies 2001;145(4):485-96.
2001: Jalal Vakili; Ludger Ständker; Michel detheux; Gilbert Vassart; Wolf-Georg Forssmann; Marc Parmentier
Urokinase plasminogen activator and plasmin efficiently convert hemofiltrate CC chemokine 1 into its active.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(6):3406-13.
2001: Masato Kotani; Michel detheux; A Vandenbogaerde; David Communi; Jean-Marie Vanderwinden; Emmanuel Le Poul; Stéphane Brézillon; R Tyldesley; N Suarez-Huerta; F Vandeput; Cédric Blanpain; S N Schiffmann; Gilbert Vassart; Marc Parmentier
The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54.
The Journal of biological chemistry 2001;276(37):34631-6.
2001: S Cornelis; Sandrine Uttenweiler; Valérie Panneels; Gilbert Vassart; Sabine Costagliola
Purification and characterization of a soluble bioactive amino-terminal extracellular domain of the human thyrotropin receptor.
Biochemistry 2001;40(33):9860-9.
2001: Bernard Corvilain; Jacqueline Van Sande; Jacques E Dumont; Gilbert Vassart
Somatic and germline mutations of the TSH receptor and thyroid diseases.
Clinical endocrinology 2001;55(2):143-58.
2001: Su-Chin Ho; Jacqueline Van Sande; Anne Lefort; Gilbert Vassart; Sabine Costagliola
Effects of mutations involving the highly conserved S281HCC motif in the extracellular domain of the thyrotropin (TSH) receptor on TSH binding and constitutive activity.
Endocrinology 2001;142(7):2760-7.
2001: Cédric Blanpain; Valérie Wittamer; Jean-Marie Vanderwinden; Alain Boom; B Renneboog; Benhur Lee; Emmanuel Le Poul; L El Asmar; Cédric Govaerts; Gilbert Vassart; Robert W Doms; Marc Parmentier
Palmitoylation of CCR5 is critical for receptor trafficking and efficient activation of intracellular signaling pathways.
The Journal of biological chemistry 2001;276(26):23795-804.
2001: Cédric Govaerts; Anne Lefort; Sabine Costagliola; Shoshana J Wodak; Juan A Ballesteros; Jacqueline Van Sande; Leonardo Pardo; Gilbert Vassart
A conserved Asn in transmembrane helix 7 is an on/off switch in the activation of the thyrotropin receptor.
The Journal of biological chemistry 2001;276(25):22991-9.
2001: Béatrice Gulbis; Frédéric Cotton; V Hansen; Alina Ferster; Michèle Toppet; Pascale Cochaux; Jasmine Parma; Gilbert Vassart; Pierre Fondu; Françoise Vertongen
[Prevention of hemoglobinopathies in Brussels: a necessity?].
Revue médicale de Bruxelles 2001;22(3):133-40.
2001: Masato Kotani; Catherine Mollereau; Michel detheux; Emmanuel Le Poul; Stéphane Brézillon; Jalal Vakili; Honoré Mazarguil; Gilbert Vassart; Jean-Marie Zajac; Marc Parmentier
Functional characterization of a human receptor for neuropeptide FF and related peptides.
British journal of pharmacology 2001;133(1):138-44.
2001: Cédric Govaerts; Cédric Blanpain; Xavier Deupi; Sébastien Ballet; Juan A Ballesteros; Shoshana J Wodak; Gilbert Vassart; Leonardo Pardo; Marc Parmentier
The TXP motif in the second transmembrane helix of CCR5. A structural determinant of chemokine-induced activation.
The Journal of biological chemistry 2001;276(16):13217-25.
2001: R Demeester; Jasmine Parma; Pascale Cochaux; Gilbert Vassart; Marc J Abramowicz
A rare variant, I852M, of the RET proto-oncogene in a patient with medullary thyroid carcinoma at age 20 years.
Human mutation 2001;17(4):354.
2001: Catheline Vilain; Catherine Rydlewski; Laurence Duprez; Claudine Heinrichs; Marc J Abramowicz; P Malvaux; B Renneboog; Jasmine Parma; Sabine Costagliola; Gilbert Vassart
Autosomal dominant transmission of congenital thyroid hypoplasia due to loss-of-function mutation of PAX8.
The Journal of clinical endocrinology and metabolism 2001;86(1):234-8.
2000: Serena Emiliani; E G Merino; Marc Van Den Bergh; Marc Abramowicz; Gilbert Vassart; Yvon Englert; Danièle Delneste
Re-analysis by fluorescence in situ hybridisation of spare embryos cultured until Day 5 after preimplantation genetic diagnosis for a 47, XYY infertile patient demonstrates a high incidence of diploid mosaic embryos: a case report.
Prenatal diagnosis 2000;20(13):1063-6.
2000: Christian M Moya; Fernando Mendive; Carina M Rivolta; Gilbert Vassart; Héctor M Targovnik
Genomic organization of the 5' region of the human thyroglobulin gene.
European journal of endocrinology / European Federation of Endocrine Societies 2000;143(6):789-98.
2000: Michel detheux; Ludger Ständker; Jalal Vakili; Jan Münch; Ulf Forssmann; Knut Adermann; Stefan Pöhlmann; Gilbert Vassart; F Kirchhoff; Marc Parmentier; Wolf-Georg Forssmann
Natural proteolytic processing of hemofiltrate CC chemokine 1 generates a potent CC chemokine receptor (CCR)1 and CCR5 agonist with anti-HIV properties.
The Journal of experimental medicine 2000;192(10):1501-8.
2000: H Mircescu; Jasmine Parma; Celine Huot; Cheri Deal; Luc L Oligny; Gilbert Vassart; Guy Van Vliet
Hyperfunctioning malignant thyroid nodule in an 11-year-old girl: pathologic and molecular studies.
The Journal of pediatrics 2000;137(4):585-7.
2000: Cédric Blanpain; Benhur Lee; M Tackoen; Bridget A Puffer; A Boom; Frédérick Libert; Matthew Sharron; Valérie Wittamer; Gilbert Vassart; Robert W Doms; Marc Parmentier
Multiple nonfunctional alleles of CCR5 are frequent in various human populations.
Blood 2000;96(5):1638-45.
2000: Xavier De Deken; Dantong Wang; Marie-Christine Many; Sabine Costagliola; Frédérick Libert; Gilbert Vassart; Jacques E Dumont; Françoise Miot
Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family.
The Journal of biological chemistry 2000;275(30):23227-33.
2000: Joachim Pohlenz; Laurence Duprez; Roy E Weiss; Gilbert Vassart; Samuel Refetoff; Sabine Costagliola
Failure of membrane targeting causes the functional defect of two mutant sodium iodide symporters.
The Journal of clinical endocrinology and metabolism 2000;85(7):2366-9.
2000: Claudine Heinrichs; Jasmine Parma; Neal H Scherberg; F Delange; Guy Van Vliet; Laurence Duprez; Pierre Bourdoux; P Bergmann; Gilbert Vassart; Samuel Refetoff
Congenital central isolated hypothyroidism caused by a homozygous mutation in the TSH-beta subunit gene.
Thyroid : official journal of the American Thyroid Association 2000;10(5):387-91.
2000: Sabine Costagliola; Marie-Christine Many; Jean-François Denef; J Pohlenz; S Refetoff; Gilbert Vassart
Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease.
The Journal of clinical investigation 2000;105(6):803-11.
1999: Cédric Blanpain; Benjamin J Doranz; J Vakili; J Rucker; Cédric Govaerts; Sarah S W Baik; O Lorthioir; Isabelle Migeotte; Frédérick Libert; Françoise Baleux; Gilbert Vassart; Robert W Doms; Marc Parmentier
Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein.
The Journal of biological chemistry 1999;274(49):34719-27.
1999: Sabine Costagliola; T Sunthorntepvarakul; Isabelle Migeotte; Jacqueline Van Sande; A M Kajava; S Refetoff; Gilbert Vassart
Structure-function relationships of two loss-of-function mutations of the thyrotropin receptor gene.
Thyroid : official journal of the American Thyroid Association 1999;9(10):995-1000.
1999: Cédric Blanpain; Isabelle Migeotte; Benhur Lee; J Vakili; Benjamin J Doranz; Cédric Govaerts; Gilbert Vassart; Robert W Doms; Marc Parmentier
CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist.
Blood 1999;94(6):1899-905.
1999: Fernando Mendive; Carina M Rivolta; Gilbert Vassart; Héctor M Targovnik
Genomic organization of the 3' region of the human thyroglobulin gene.
Thyroid : official journal of the American Thyroid Association 1999;9(9):903-12.
1999: Dov Tiosano; Silvana Pannain; Gilbert Vassart; J Parma; Ruth Gershoni-Baruch; Hanna Mandel; R Lotan; Y Zaharan; Menucha Pery; Roy E Weiss; Samuel Refetoff; Ze'ev Hochberg
The hypothyroidism in an inbred kindred with congenital thyroid hormone and glucocorticoid deficiency is due to a mutation producing a truncated thyrotropin receptor.
Thyroid : official journal of the American Thyroid Association 1999;9(9):887-94.
1999: Bruno Pichon; Gilbert Vassart; Daniel Christophe
A canonical nerve growth factor-induced gene-B response element appears not to be involved in the cyclic adenosine monophosphate-dependent expression of differentiation in thyrocytes.
Molecular and cellular endocrinology 1999;154(1-2):21-7.
1999: Cédric Blanpain; Benhur Lee; J Vakili; Benjamin J Doranz; Cédric Govaerts; Isabelle Migeotte; Matthew Sharron; V Dupriez; Gilbert Vassart; Robert W Doms; Marc Parmentier
Extracellular cysteines of CCR5 are required for chemokine binding, but dispensable for HIV-1 coreceptor activity.
The Journal of biological chemistry 1999;274(27):18902-8.
1999: Marie-Christine Many; Sabine Costagliola; M Detrait; F Denef; Gilbert Vassart; M C Ludgate
Development of an animal model of autoimmune thyroid eye disease.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(8):4966-74.
1999: Laurence Duprez; Jasmine Parma; Jacqueline Van Sande; Patrice Rodien; C Sabine; Marc J Abramowicz; Jacques E Dumont; Gilbert Vassart
Pathology of the TSH receptor.
Journal of pediatric endocrinology & metabolism : JPEM 1999;12 Suppl 1():295-302.
1999: Daphne Hsu-Chin Khoo; J Parma; C Rajasoorya; Su-Chin Ho; Gilbert Vassart
A germline mutation of the thyrotropin receptor gene associated with thyrotoxicosis and mitral valve prolapse in a Chinese family.
The Journal of clinical endocrinology and metabolism 1999;84(4):1459-62.
1999: A Maho; A Bensimon; Gilbert Vassart; Marc Parmentier
Mapping of the CCXCR1, CX3CR1, CCBP2 and CCR9 genes to the CCR cluster within the 3p21.3 region of the human genome.
Cytogenetics and cell genetics 1999;87(3-4):265-8.
1998: Patrice Rodien; C Brémont; M L Sanson; Jasmine Parma; Jacqueline Van Sande; Sabine Costagliola; JP Luton; Gilbert Vassart; Laurence Duprez
Familial gestational hyperthyroidism caused by a mutant thyrotropin receptor hypersensitive to human chorionic gonadotropin.
The New England journal of medicine 1998;339(25):1823-6.
1998: Patrice Rodien; Filomena Cetani; Sabine Costagliola; Massimo Tonacchera; Laurence Duprez; T Minegishi; Cédric Govaerts; Gilbert Vassart
Evidences for an allelic variant of the human LC/CG receptor rather than a gene duplication: functional comparison of wild-type and variant receptors.
The Journal of clinical endocrinology and metabolism 1998;83(12):4431-4.
1998: Laurence Duprez; Jasmine Parma; Jacqueline Van Sande; Patrice Rodien; Jacques E Dumont; Gilbert Vassart; Marc J Abramowicz
TSH Receptor Mutations and Thyroid Disease.
Trends in endocrinology and metabolism: TEM 1998;9(4):133-40.
1998: Marian Ludgate; Michele Crisp; C Lane; Sabine Costagliola; Gilbert Vassart; Anthony P Weetman; C Daunerie; Marie-Christine Many
The thyrotropin receptor in thyroid eye disease.
Thyroid : official journal of the American Thyroid Association 1998;8(5):411-3.
1998: M Samson; Aimee Edinger; Patrick Stordeur; J Rucker; Valérie Verhasselt; Matthew Sharron; Cédric Govaerts; C Mollereau; Gilbert Vassart; Robert W Doms; Marc Parmentier
ChemR23, a putative chemoattractant receptor, is expressed in monocyte-derived dendritic cells and macrophages and is a coreceptor for SIV and some primary HIV-1 strains.
European journal of immunology 1998;28(5):1689-700.
1998: Nancy Gagné; Jasmine Parma; Cheri Deal; Gilbert Vassart; Guy Van Vliet
Apparent congenital athyreosis contrasting with normal plasma thyroglobulin levels and associated with inactivating mutations in the thyrotropin receptor gene: are athyreosis and ectopic thyroid distinct entities?
The Journal of clinical endocrinology and metabolism 1998;83(5):1771-5.
1998: Héctor M Targovnik; Gustavo Daniel Frechtel; Fernando Mendive; J Vono; P Cochaux; Gilbert Vassart; Geraldo Medeiros-Neto
Evidence for the segregation of three different mutated alleles of the thyroglobulin gene in a Brazilian family with congenital goiter and hypothyroidism.
Thyroid : official journal of the American Thyroid Association 1998;8(4):291-7.
1998: Frédérick Libert; P Cochaux; G Beckman; M Samson; M Aksenova; A Cao; A Czeizel; M Claustres; C de la Rúa; M Ferrari; C Ferrec; G Glover; B Grinde; Sefik Güran; Vaidutis Kucinskas; J Lavinha; B Mercier; Gonul Ogur; L Peltonen; C Rosatelli; M Schwartz; V Spitsyn; L Timar; LE Beckman; Marc Parmentier; Gilbert Vassart
The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe.
Human molecular genetics 1998;7(3):399-406.
1998: Sabine Costagliola; Patrice Rodien; Marie-Christine Many; Marian Ludgate; Gilbert Vassart
Genetic immunization against the human thyrotropin receptor causes thyroiditis and allows production of monoclonal antibodies recognizing the native receptor.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(3):1458-65.
1997: Jun Xie; Silvana Pannain; Joachim Pohlenz; Roy E Weiss; K Moltz; M Morlot; Carmela Asteria; Luca Persani; Paolo Beck-Peccoz; J Parma; Gilbert Vassart; Samuel Refetoff
Resistance to thyrotropin (TSH) in three families is not associated with mutations in the TSH receptor or TSH.
The Journal of clinical endocrinology and metabolism 1997;82(12):3933-40.
1997: M Samson; Greg La Rosa; Frédérick Libert; P Paindavoine; Michel detheux; Gilbert Vassart; Marc Parmentier
The second extracellular loop of CCR5 is the major determinant of ligand specificity.
The Journal of biological chemistry 1997;272(40):24934-41.
1997: P Vanderhaeghen; S Schurmans; Gilbert Vassart; M Parmentier
Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome.
Biochemical and biophysical research communications 1997;237(2):283-7.
1997: Fernando Mendive; L C Rossetti; Gilbert Vassart; Héctor M Targovnik
Identification of a new thyroglobulin variant: a guanine-to-adenine transition resulting in the substitution of arginine 2510 by glutamine.
Thyroid : official journal of the American Thyroid Association 1997;7(4):587-91.
1997: Jasmine Parma; Laurence Duprez; Jacqueline Van Sande; J Hermans; Pierre Rocmans; Guy Van Vliet; Sabine Costagliola; Patrice Rodien; Jacques E Dumont; Gilbert Vassart
Diversity and prevalence of somatic mutations in the thyrotropin receptor and Gs alpha genes as a cause of toxic thyroid adenomas.
The Journal of clinical endocrinology and metabolism 1997;82(8):2695-701.
1997: Laurence Duprez; Jasmine Parma; Sabine Costagliola; J Hermans; Jacqueline Van Sande; Jacques E Dumont; Gilbert Vassart
Constitutive activation of the TSH receptor by spontaneous mutations affecting the N-terminal extracellular domain.
FEBS letters 1997;409(3):469-74.
1997: Marc J Abramowicz; Laurence Duprez; Jasmine Parma; Gilbert Vassart; Claudine Heinrichs
Familial congenital hypothyroidism due to inactivating mutation of the thyrotropin receptor causing profound hypoplasia of the thyroid gland.
The Journal of clinical investigation 1997;99(12):3018-24.
1997: V Berg; Gilbert Vassart; D Christophe
A zinc-dependent DNA-binding activity co-operates with cAMP-responsive-element-binding protein to activate the human thyroglobulin enhancer.
The Biochemical journal 1997;323 ( Pt 2)():349-57.
1997: S Rana; G Besson; D G Cook; J Rucker; RJ Smyth; Yanjie Yi; JD Turner; HH Guo; JG Du; Stephen Peiper; Ehud Lavi; M Samson; Frédérick Libert; C Liesnard; Gilbert Vassart; Robert W Doms; Marc Parmentier; Ronald G Collman
Role of CCR5 in infection of primary macrophages and lymphocytes by macrophage-tropic strains of human immunodeficiency virus: resistance to patient-derived and prototype isolates resulting from the delta ccr5 mutation.
Journal of virology 1997;71(4):3219-27.
1997: P Vanderhaeghen; S Schurmans; Gilbert Vassart; M Parmentier
Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.
Genomics 1997;39(3):239-46.
1997: Gilbert Vassart
New pathophysiological mechanisms for hyperthyroidism.
Hormone research 1997;48 Suppl 4():47-50.
1997: N Uyttersprot; A Allgeier; M Baptist; Daniel Christophe; F Coppee; Katia Coulonval; S Deleu; F Depoortere; Sarah Dremier; Françoise Lamy; C Ledent; Carine Maenhaut; Françoise Miot; V Panneels; Jasmine Parma; M Parmentier; Isabelle Pirson; Viviane Pohl; P Roger; Valérie Savonet; M Taton; M Tonacchera; Jacqueline Van Sande; Françoise Wilkin; Gilbert Vassart
The cAMP in thyroid: from the TSH receptor to mitogenesis and tumorigenesis.
Advances in second messenger and phosphoprotein research 1997;31():125-40.
1997: Laurence Duprez; J Hermans; Jacqueline Van Sande; Jacques E Dumont; Gilbert Vassart; Jasmine Parma
Two autonomous nodules of a patient with multinodular goiter harbor different activating mutations of the thyrotropin receptor gene.
The Journal of clinical endocrinology and metabolism 1997;82(1):306-8.
1997: C Ledent; J F Denef; S Cottecchia; R Lefkowitz; J Dumont; Gilbert Vassart; M Parmentier
Costimulation of adenylyl cyclase and phospholipase C by a mutant alpha 1B-adrenergic receptor transgene promotes malignant transformation of thyroid follicular cells.
Endocrinology 1997;138(1):369-78.
1996: M Samson; Patrick Stordeur; O Labbé; P Soularue; Gilbert Vassart; M Parmentier
Molecular cloning and chromosomal mapping of a novel human gene, ChemR1, expressed in T lymphocytes and polymorphonuclear cells and encoding a putative chemokine receptor.
European journal of immunology 1996;26(12):3021-8.
1996: Sarah Dremier; F Coppée; F Delange; Gilbert Vassart; Jacques E Dumont; Jacqueline Van Sande
Clinical review 84: Thyroid autonomy: mechanism and clinical effects.
The Journal of clinical endocrinology and metabolism 1996;81(12):4187-93.
1996: J Rucker; M Samson; Benjamin J Doranz; Frédérick Libert; Joanne F Berson; Yanjie Yi; R J Smyth; Ronald G Collman; Christopher C Broder; Gilbert Vassart; Robert W Doms; M Parmentier
Regions in beta-chemokine receptors CCR5 and CCR2b that determine HIV-1 cofactor specificity.
Cell 1996;87(3):437-46.
1996: Sabine Costagliola; Marie-Christine Many; M Stalmans-Falys; Gilbert Vassart; Marian Ludgate
Transfer of thyroiditis, with syngeneic spleen cells sensitized with the human thyrotropin receptor, to naive BALB/c and NOD mice.
Endocrinology 1996;137(11):4637-43.
1996: F Coppée; A C Gérard; J F Denef; C Ledent; Gilbert Vassart; Jacques E Dumont; M Parmentier
Early occurrence of metastatic differentiated thyroid carcinomas in transgenic mice expressing the A2a adenosine receptor gene and the human papillomavirus type 16 E7 oncogene.
Oncogene 1996;13(7):1471-82.
1996: Massimo Tonacchera; Filomena Cetani; Jasmine Parma; Jacqueline Van Sande; Gilbert Vassart; J Dumont
Oncogenic mutations in thyroid adenoma: methodological criteria.
European journal of endocrinology / European Federation of Endocrine Societies 1996;135(4):444-6.
1996: M Samson; P Soularue; Gilbert Vassart; M Parmentier
The genes encoding the human CC-chemokine receptors CC-CKR1 to CC-CKR5 (CMKBR1-CMKBR5) are clustered in the p21.3-p24 region of chromosome 3.
Genomics 1996;36(3):522-6.
1996: M Samson; Frédérick Libert; Benjamin J Doranz; J Rucker; C Liesnard; Claire M Farber; S Saragosti; C Lapoumeroulie; J Cognaux; C Forceille; G Muyldermans; C Verhofstede; G Burtonboy; M Georges; T Imai; S Rana; Yanjie Yi; R J Smyth; Ronald G Collman; Robert W Doms; Gilbert Vassart; M Parmentier
Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene.
Nature 1996;382(6593):722-5.
1996: P Van Renterghem; Gilbert Vassart; Daniel Christophe
Pax 8 expression in primary cultured dog thyrocyte is increased by cyclic AMP.
Biochimica et biophysica acta 1996;1307(1):97-103.
1996: V Berg; Gilbert Vassart; D Christophe
Identification of a thyroid-specific and cAMP-responsive enhancer in the upstream sequences of the human thyroglobulin promoter.
Biochimica et biophysica acta 1996;1307(1):35-8.
1996: Massimo Tonacchera; Jacqueline Van Sande; Jasmine Parma; Laurence Duprez; Filomena Cetani; Sabine Costagliola; Jacques E Dumont; Gilbert Vassart
TSH receptor and disease.
Clinical endocrinology 1996;44(6):621-33.
1996: Massimo Tonacchera; Filomena Cetani; Sabine Costagliola; Jacqueline Van Sande; S Refetoff; Gilbert Vassart
Functional characteristics of a variant thyrotropin receptor.
European journal of biochemistry / FEBS 1996;238(2):490-4.
1996: Jacqueline Van Sande; C Massart; Sabine Costagliola; A Allgeier; Filomena Cetani; Gilbert Vassart; Jacques E Dumont
Specific activation of the thyrotropin receptor by trypsin.
Molecular and cellular endocrinology 1996;119(2):161-8.
1996: Massimo Tonacchera; Jacqueline Van Sande; Filomena Cetani; S Swillens; C Schvartz; P Winiszewski; L Portmann; Jacques E Dumont; Gilbert Vassart; Jasmine Parma
Functional characteristics of three new germline mutations of the thyrotropin receptor gene causing autosomal dominant toxic thyroid hyperplasia.
The Journal of clinical endocrinology and metabolism 1996;81(2):547-54.
1996: Filomena Cetani; Massimo Tonacchera; Gilbert Vassart
Differential effects of NaCl concentration on the constitutive activity of the thyrotropin and the luteinizing hormone/chorionic gonadotropin receptors.
FEBS letters 1996;378(1):27-31.
1996: C Ledent; F Coppée; Jacques E Dumont; Gilbert Vassart; M Parmentier
Transgenic models for proliferative and hyperfunctional thyroid diseases.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1996;104 Suppl 3():43-6.
1996: R Paschke; Jacqueline Van Sande; Jasmine Parma; Gilbert Vassart
The TSH receptor and thyroid diseases.
Baillière's clinical endocrinology and metabolism 1996;10(1):9-27.
1996: Gilbert Vassart; Jacqueline Van Sande; Jasmine Parma; Massimo Tonacchera; Laurence Duprez; S Swillens; J Dumont
Activating mutations of the TSH receptor gene cause thyroid diseases.
Annales d'endocrinologie 1996;57(1):50-4.
1996: Massimo Tonacchera; Sabine Costagliola; Filomena Cetani; J Ducobu; P Stordeur; Gilbert Vassart; Marian Ludgate
Patient with monoclonal gammopathy, thyrotoxicosis, pretibial myxedema and thyroid-associated ophthalmopathy; demonstration of direct binding of autoantibodies to the thyrotropin receptor.
European journal of endocrinology / European Federation of Endocrine Societies 1996;134(1):97-103.
1995: Sabine Costagliola; Marie-Christine Many; M Stalmans-Falys; Gilbert Vassart; Marian Ludgate
The autoimmune response induced by immunising female mice with recombinant human thyrotropin receptor varies with the genetic background.
Molecular and cellular endocrinology 1995;115(2):199-206.
1995: Filomena Cetani; Sabine Costagliola; Massimo Tonacchera; V Panneels; Gilbert Vassart; Marian Ludgate
The thyroperoxidase doublet is not produced by alternative splicing.
Molecular and cellular endocrinology 1995;115(2):125-32.
1995: Gilbert Vassart; F Desarnaud; Laurence Duprez; D Eggerickx; O Labbé; F Libert; C Mollereau; Jasmine Parma; R Paschke; Massimo Tonacchera
The G protein-coupled receptor family and one of its members, the TSH receptor.
Annals of the New York Academy of Sciences 1995;766():23-30.
1995: Jacqueline Van Sande; Jasmine Parma; Massimo Tonacchera; S Swillens; J Dumont; Gilbert Vassart
Somatic and germline mutations of the TSH receptor gene in thyroid diseases.
The Journal of clinical endocrinology and metabolism 1995;80(9):2577-85.
1995: D Eggerickx; J F Denef; O Labbe; Y Hayashi; S Refetoff; Gilbert Vassart; M Parmentier; F Libert
Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase.
The Biochemical journal 1995;309 ( Pt 3)():837-43.
1995: P Van Renterghem; Sarah Dremier; Gilbert Vassart; Daniel Christophe
Study of TTF-1 gene expression in dog thyrocytes in primary culture.
Molecular and cellular endocrinology 1995;112(1):83-93.
1995: Jasmine Parma; Jacqueline Van Sande; S Swillens; Massimo Tonacchera; J Dumont; Gilbert Vassart
Somatic mutations causing constitutive activity of the thyrotropin receptor are the major cause of hyperfunctioning thyroid adenomas: identification of additional mutations activating both the cyclic adenosine 3',5'-monophosphate and inositol phosphate-Ca2+ cascades.
Molecular endocrinology (Baltimore, Md.) 1995;9(6):725-33.
1995: C Ledent; A Marcotte; Jacques E Dumont; Gilbert Vassart; M Parmentier
Differentiated carcinomas develop as a consequence of the thyroid specific expression of a thyroglobulin-human papillomavirus type 16 E7 transgene.
Oncogene 1995;10(9):1789-97.
1995: Jacqueline Van Sande; S Swillens; C Gerard; A Allgeier; C Massart; Gilbert Vassart; Jacques E Dumont
In Chinese hamster ovary K1 cells dog and human thyrotropin receptors activate both the cyclic AMP and the phosphatidylinositol 4,5-bisphosphate cascades in the presence of thyrotropin and the cyclic AMP cascade in its absence.
European journal of biochemistry / FEBS 1995;229(2):338-43.
1995: Peter Kopp; Jacqueline Van Sande; Jasmine Parma; Laurence Duprez; Hans Gerber; E Joss; J Larry Jameson; Jacques E Dumont; Gilbert Vassart
Brief report: congenital hyperthyroidism caused by a mutation in the thyrotropin-receptor gene.
The New England journal of medicine 1995;332(3):150-4.
1995: M E Ludgate; Gilbert Vassart
The thyrotropin receptor as a model to illustrate receptor and receptor antibody diseases.
Baillière's clinical endocrinology and metabolism 1995;9(1):95-113.
1995: Massimo Tonacchera; Filomena Cetani; Sabine Costagliola; L Alcalde; R Uibo; Gilbert Vassart; Marian Ludgate
Mapping thyroid peroxidase epitopes using recombinant protein fragments.
European journal of endocrinology / European Federation of Endocrine Societies 1995;132(1):53-61.
1994: R Paschke; Massimo Tonacchera; Jacqueline Van Sande; Jasmine Parma; Gilbert Vassart
Identification and functional characterization of two new somatic mutations causing constitutive activation of the thyrotropin receptor in hyperfunctioning autonomous adenomas of the thyroid.
The Journal of clinical endocrinology and metabolism 1994;79(6):1785-9.
1994: R Paschke; A Metcalfe; L Alcalde; Gilbert Vassart; A Weetman; Marian Ludgate
Presence of nonfunctional thyrotropin receptor variant transcripts in retroocular and other tissues.
The Journal of clinical endocrinology and metabolism 1994;79(5):1234-8.
1994: Sabine Costagliola; Marie-Christine Many; M Stalmans-Falys; Massimo Tonacchera; Gilbert Vassart; Marian Ludgate
Recombinant thyrotropin receptor and the induction of autoimmune thyroid disease in BALB/c mice: a new animal model.
Endocrinology 1994;135(5):2150-9.
1994: Sabine Costagliola; L Alcalde; J Ruf; Gilbert Vassart; Marian Ludgate
Overexpression of the extracellular domain of the thyrotrophin receptor in bacteria; production of thyrotrophin-binding inhibiting immunoglobulins.
Journal of molecular endocrinology 1994;13(1):11-21.
1994: O Labbé; F Desarnaud; D Eggerickx; Gilbert Vassart; M Parmentier
Molecular cloning of a mouse melanocortin 5 receptor gene widely expressed in peripheral tissues.
Biochemistry 1994;33(15):4543-9.
1994: F Desarnaud; O Labbe; D Eggerickx; Gilbert Vassart; M Parmentier
Molecular cloning, functional expression and pharmacological characterization of a mouse melanocortin receptor gene.
The Biochemical journal 1994;299 ( Pt 2)():367-73.
1994: C Ledent; M Parmentier; Gilbert Vassart; Jacques E Dumont
Models of thyroid goiter and tumors in transgenic mice.
Molecular and cellular endocrinology 1994;100(1-2):167-9.
1994: Jasmine Parma; Laurence Duprez; Jacqueline Van Sande; R Paschke; Massimo Tonacchera; J Dumont; Gilbert Vassart
Constitutively active receptors as a disease-causing mechanism.
Molecular and cellular endocrinology 1994;100(1-2):159-62.
1994: Bruno Pichon; Christiane Christophe-Hobertus; Gilbert Vassart; Daniel Christophe
Unmethylated thyroglobulin promoter may be repressed by methylation of flanking DNA sequences.
The Biochemical journal 1994;298 Pt 3():537-41.
1994: Sabine Costagliola; L Alcalde; Massimo Tonacchera; J Ruf; Gilbert Vassart; Marian Ludgate
Induction of thyrotropin receptor (TSH-R) autoantibodies and thyroiditis in mice immunised with the recombinant TSH-R.
Biochemical and biophysical research communications 1994;199(2):1027-34.
1994: C Ledent; Jasmine Parma; J Dumont; Gilbert Vassart; Héctor M Targovnik
Molecular genetics of thyroid diseases.
European journal of endocrinology / European Federation of Endocrine Societies 1994;130(1):8-14.
1993: P Vanderhaeghen; S Schurmans; Gilbert Vassart; M Parmentier
Olfactory receptors are displayed on dog mature sperm cells.
The Journal of cell biology 1993;123(6 Pt 1):1441-52.
1993: Jacqueline Van Sande; A Allgeier; C Massart; A Czernilofsky; Gilbert Vassart; Jacques E Dumont; Carine Maenhaut
The human and dog 5-HT1D receptors can both activate and inhibit adenylate cyclase in transfected cells.
European journal of pharmacology 1993;247(2):177-84.
1993: Jasmine Parma; Laurence Duprez; Jacqueline Van Sande; Pascale Cochaux; C Gervy; J Mockel; J Dumont; Gilbert Vassart
Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas.
Nature 1993;365(6447):649-51.
1993: Héctor M Targovnik; Geraldo Medeiros-Neto; V Varela; P Cochaux; B L Wajchenberg; Gilbert Vassart
A nonsense mutation causes human hereditary congenital goiter with preferential production of a 171-nucleotide-deleted thyroglobulin ribonucleic acid messenger.
The Journal of clinical endocrinology and metabolism 1993;77(1):210-5.
1993: Héctor M Targovnik; G D Frechtel; V Varela; B L Wajchenberg; Gilbert Vassart; J Dumont; Geraldo Medeiros-Neto
Human thyroid tissue do not express thyroalbumin.
Journal of endocrinological investigation 1993;16(6):415-9.
1993: R Paschke; R Elisei; Gilbert Vassart; Marian Ludgate
Lack of evidence supporting the presence of mRNA for the thyrotropin receptor in extra-ocular muscle.
Journal of endocrinological investigation 1993;16(5):329-32.
1993: C Mollereau; F Muscatelli; M G Mattei; Gilbert Vassart; M Parmentier
The high-affinity interleukin 8 receptor gene (IL8RA) maps to the 2q33-q36 region of the human genome: cloning of a pseudogene (IL8RBP) for the low-affinity receptor.
Genomics 1993;16(1):248-51.
1993: M Parmentier; F Libert; J Perret; D Eggerickx; C Ledent; S Schurmans; E Raspe; Jacques E Dumont; Gilbert Vassart
Cloning and characterization of G protein-coupled receptors.
Advances in second messenger and phosphoprotein research 1993;28():11-8.
1993: A Donda; F Javaux; P Van Renterghem; C Gervy-Decoster; Gilbert Vassart; Daniel Christophe
Human, bovine, canine and rat thyroglobulin promoter sequences display species-specific differences in an in vitro study.
Molecular and cellular endocrinology 1993;90(2):R23-6.
1993: S Schurmans; F Muscatelli; F Miot; M G Mattei; Gilbert Vassart; M Parmentier
The OLFR1 gene encoding the HGMP07E putative olfactory receptor maps to the 17p13-->p12 region of the human genome and reveals an MspI restriction fragment length polymorphism.
Cytogenetics and cell genetics 1993;63(3):200-4.
1993: Gilbert Vassart
[Molecular genetics of thyroid diseases].
Bulletin et mémoires de l'Académie royale de médecine de Belgique 1993;148(10):337-41.
1993: Gilbert Vassart; Jasmine Parma; Laurence Duprez; Carine Maenhaut; C Ledent; Jacqueline Van Sande; G Brabant; J Dumont
[Thyrotropin receptor. Control of the gene expression and structure function relationships].
Annales d'endocrinologie 1993;54(6):367-8.
1992: Sabine Costagliola; S Swillens; P Niccoli; Jacques E Dumont; Gilbert Vassart; Marian Ludgate
Binding assay for thyrotropin receptor autoantibodies using the recombinant receptor protein.
The Journal of clinical endocrinology and metabolism 1992;75(6):1540-4.
1992: Christiane Christophe-Hobertus; A Donda; F Javaux; Gilbert Vassart; Daniel Christophe
Identification of a transcriptional enhancer upstream from the bovine thyroglobulin gene.
Molecular and cellular endocrinology 1992;88(1-3):31-7.
1992: M J Abramowicz; Héctor M Targovnik; V Varela; P Cochaux; León Krawiec; Mario A Pisarev; F V Propato; Guillermo Juvenal; H A Chester; Gilbert Vassart
Identification of a mutation in the coding sequence of the human thyroid peroxidase gene causing congenital goiter.
The Journal of clinical investigation 1992;90(4):1200-4.
1992: Jacqueline Van Sande; C Lejeune; M Ludgate; D S Munro; Gilbert Vassart; Jacques E Dumont; J Mockel
Thyroid stimulating immunoglobulins, like thyrotropin activate both the cyclic AMP and the PIP2 cascades in CHO cells expressing the TSH receptor.
Molecular and cellular endocrinology 1992;88(1-3):R1-5.
1992: C Erneux; N Roeckel; K Takazawa; P Mailleux; Gilbert Vassart; M G Mattei
Localization of the genes for human inositol 1,4,5-trisphosphate 3-kinase A (ITPKA) and B (ITPKB) to chromosome regions 15q14-q21 and 1q41-q43, respectively, by in situ hybridization.
Genomics 1992;14(2):546-7.
1992: D Eggerickx; E Raspe; D Bertrand; Gilbert Vassart; M Parmentier
Molecular cloning, functional expression and pharmacological characterization of a human bradykinin B2 receptor gene.
Biochemical and biophysical research communications 1992;187(3):1306-13.
1992: F Libert; Jacqueline Van Sande; A Lefort; A Czernilofsky; Jacques E Dumont; Gilbert Vassart; Helmut A Ensinger; Klaus Mendla
Cloning and functional characterization of a human A1 adenosine receptor.
Biochemical and biophysical research communications 1992;187(2):919-26.
1992: Gilbert Vassart; Jacques E Dumont
The thyrotropin receptor and the regulation of thyrocyte function and growth.
Endocrine reviews 1992;13(3):596-611.
1992: F Javaux; F Bertaux; A Donda; H Francis-Lang; Gilbert Vassart; R DiLauro; Daniel Christophe
Functional role of TTF-1 binding sites in bovine thyroglobulin promoter.
FEBS letters 1992;300(3):222-6.
1992: Héctor M Targovnik; P Cochaux; Daniel Corach; Gilbert Vassart
Identification of a minor Tg mRNA transcript in RNA from normal and goitrous thyroids.
Molecular and cellular endocrinology 1992;84(1-2):R23-6.
1992: Carine Maenhaut; G Brabant; Gilbert Vassart; Jacques E Dumont
In vitro and in vivo regulation of thyrotropin receptor mRNA levels in dog and human thyroid cells.
The Journal of biological chemistry 1992;267(5):3000-7.
1992: C Ledent; Jacques E Dumont; Gilbert Vassart; M Parmentier
Thyroid expression of an A2 adenosine receptor transgene induces thyroid hyperplasia and hyperthyroidism.
The EMBO journal 1992;11(2):537-42.
1992: Gilbert Vassart; G Brabant; Sabine Costagliola; D Danguy; C Gérard; F Libert; Marian Ludgate; Carine Maenhaut; M Parmentier; R Paschke
Molecular genetics of the thyrotropin receptor.
Experimental and clinical endocrinology 1992;100(1-2):9-11.
1992: Z G Zhang; Q Dong; Patrice Rodien; L Alcalde; N Bernard; A Boucher; Mario Salvi; B Arthurs; Gilbert Vassart; Marian Ludgate
Antibodies in the serum of patients with autoimmune thyroid disorders react with a recombinant 98 amino acid fragment of a full length 64 kDa eye muscle membrane protein which is also expressed in the thyroid.
Autoimmunity 1992;13(2):151-7.
1992: Marian Ludgate; Sabine Costagliola; D Danguy; J Perret; Gilbert Vassart
Recombinant TSH-receptor for determination of TSH-receptor-antibodies.
Experimental and clinical endocrinology 1992;100(1-2):73-4.
1992: Gilbert Vassart; M Parmentier; F Libert; D Eggerickx; C Gerard; Carine Maenhaut; C Mollereau; J Perret; S Schurman; J Van Sande
Identification of orphan G protein-coupled receptors.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():147A-148A.
1991: Tamio Ieiri; P Cochaux; Héctor M Targovnik; M Suzuki; S Shimoda; J Perret; Gilbert Vassart
A 3' splice site mutation in the thyroglobulin gene responsible for congenital goiter with hypothyroidism.
The Journal of clinical investigation 1991;88(6):1901-5.
1991: Carine Maenhaut; Jacqueline Van Sande; C Massart; C Dinsart; F Libert; E Monferini; E Giraldo; H Ladinsky; Gilbert Vassart; Jacques E Dumont
The orphan receptor cDNA RDC4 encodes a 5-HT1D serotonin receptor.
Biochemical and biophysical research communications 1991;180(3):1460-8.
1991: M Parmentier; E Passage; M G Mattei; Gilbert Vassart
A new human hypervariable locus (K29) maps to the q37.3 region of chromosome 2 and reveals a fingerprint.
Genomics 1991;11(3):760-2.
1991: A Donda; Gilbert Vassart; Daniel Christophe
Isolation and characterization of the canine thyroglobulin gene promoter region.
Biochimica et biophysica acta 1991;1090(2):235-7.
1991: C M Gérard; C Mollereau; Gilbert Vassart; M Parmentier
Molecular cloning of a human cannabinoid receptor which is also expressed in testis.
The Biochemical journal 1991;279 ( Pt 1)():129-34.
1991: F Libert; Marian Ludgate; C Dinsart; Gilbert Vassart
Thyroperoxidase, but not the thyrotropin receptor, contains sequential epitopes recognized by autoantibodies in recombinant peptides expressed in the pUEX vector.
The Journal of clinical endocrinology and metabolism 1991;73(4):857-60.
1991: Serge N Schiffmann; F Libert; Gilbert Vassart; JJ Vanderhaeghen
Distribution of adenosine A2 receptor mRNA in the human brain.
Neuroscience letters 1991;130(2):177-81.
1991: C Ledent; J Dumont; Gilbert Vassart; M Parmentier
Thyroid adenocarcinomas secondary to tissue-specific expression of simian virus-40 large T-antigen in transgenic mice.
Endocrinology 1991;129(3):1391-401.
1991: F Libert; E Passage; M Parmentier; M J Simons; Gilbert Vassart; M G Mattei
Chromosomal mapping of A1 and A2 adenosine receptors, VIP receptor, and a new subtype of serotonin receptor.
Genomics 1991;11(1):225-7.
1991: F Libert; Serge N Schiffmann; A Lefort; M Parmentier; C Gérard; Jacques E Dumont; J J Vanderhaeghen; Gilbert Vassart
The orphan receptor cDNA RDC7 encodes an A1 adenosine receptor.
The EMBO journal 1991;10(7):1677-82.
1991: F Javaux; A Donda; Gilbert Vassart; Daniel Christophe
Cloning and sequence analysis of TFE, a helix-loop-helix transcription factor able to recognize the thyroglobulin gene promoter in vitro.
Nucleic acids research 1991;19(5):1121-7.
1991: R Elisei; Gilbert Vassart; Marian Ludgate
Demonstration of the existence of the alternatively spliced form of thyroid peroxidase in normal thyroid.
The Journal of clinical endocrinology and metabolism 1991;72(3):700-2.
1991: P Cochaux; R Van Geffel; D Baran; Gilbert Vassart
Prevalence of the major mutation of the CF gene in Belgian patients.
Advances in experimental medicine and biology 1991;290():353-4.
1991: M Parmentier; E Passage; Gilbert Vassart; M G Mattei
The human calbindin D28k (CALB1) and calretinin (CALB2) genes are located at 8q21.3----q22.1 and 16q22----q23, respectively, suggesting a common duplication with the carbonic anhydrase isozyme loci.
Cytogenetics and cell genetics 1991;57(1):41-3.
1990: Carine Maenhaut; Jacqueline Van Sande; F Libert; M Abramowicz; M Parmentier; J J Vanderhaegen; Jacques E Dumont; Gilbert Vassart; Serge N Schiffmann
RDC8 codes for an adenosine A2 receptor with physiological constitutive activity.
Biochemical and biophysical research communications 1990;173(3):1169-78.
1990: C Gérard; C Mollereau; Gilbert Vassart; M Parmentier
Nucleotide sequence of a human cannabinoid receptor cDNA.
Nucleic acids research 1990;18(23):7142.
1990: Jacqueline Van Sande; E Raspé; J Perret; C Lejeune; Carine Maenhaut; Gilbert Vassart; Jacques E Dumont
Thyrotropin activates both the cyclic AMP and the PIP2 cascades in CHO cells expressing the human cDNA of TSH receptor.
Molecular and cellular endocrinology 1990;74(1):R1-6.
1990: J Perret; Marian Ludgate; F Libert; C Gerard; Jacques E Dumont; Gilbert Vassart; M Parmentier
Stable expression of the human TSH receptor in CHO cells and characterization of differentially expressing clones.
Biochemical and biophysical research communications 1990;171(3):1044-50.
1990: P Cochaux; R van Geffel; D Baran; J Poncin; Gilbert Vassart
Prevalence of the delta F508 deletion of the cystic fibrosis gene in Belgian patients.
Human genetics 1990;85(4):400.
1990: C Streydio; S Swillens; M Georges; Claude Szpirer; Gilbert Vassart
Structure, evolution and chromosomal localization of the human pregnancy-specific beta 1-glycoprotein gene family.
Genomics 1990;7(4):661-2.
1990: C Ledent; M Parmentier; Gilbert Vassart
Tissue-specific expression and methylation of a thyroglobulin-chloramphenicol acetyltransferase fusion gene in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(16):6176-80.
1990: C Gérard; Daniel Christophe; T Compère; Gilbert Vassart
The poly (purine) poly (pyrimidine) sequence in the 5' end of the thyroglobulin gene used as a probe, identifies a DNA fingerprint in man.
Nucleic acids research 1990;18(14):4297.
1990: Serge N Schiffmann; F Libert; Gilbert Vassart; J E Dumont; JJ Vanderhaeghen
A cloned G protein-coupled protein with a distribution restricted to striatal medium-sized neurons. Possible relationship with D1 dopamine receptor.
Brain research 1990;519(1-2):333-7.
1990: Catherine Donner; P Simon; F Gosselin; Danièle Vermeylen; Fred E Avni; Corinne Liesnard; Esther Vamos; Pascale Cochaux; Gilbert Vassart; F Rodesch
[Cordocentesis: experience in 391 initial samples].
Revue médicale de Bruxelles 1990;11(6):217-22.
1990: Pascale Cochaux; T Velu; M Abramowicz; Gilbert Vassart
[Molecular and diagnostic genetics].
Revue médicale de Bruxelles 1990;11(6):188-94.
1990: Catherine Donner; P Simon; F Gosselin; Esther Vamos; Pascale Cochaux; Gilbert Vassart; F Rodesch
[Chorionic villi sampling: experience of the initial 500 samples].
Revue médicale de Bruxelles 1990;11(6):211-5.
1990: F Libert; M Parmentier; A Lefort; J E Dumont; Gilbert Vassart
Complete nucleotide sequence of a putative G protein coupled receptor: RDC1.
Nucleic acids research 1990;18(7):1917.
1990: F Libert; M Parmentier; A Lefort; J E Dumont; Gilbert Vassart
Complete nucleotide sequence of a putative G protein coupled receptor: RDC4.
Nucleic acids research 1990;18(7):1916.
1990: F Libert; M Parmentier; A Lefort; J E Dumont; Gilbert Vassart
Complete nucleotide sequence of a putative G protein coupled receptor: RDC7.
Nucleic acids research 1990;18(7):1915.
1990: F Libert; M Parmentier; A Lefort; J E Dumont; Gilbert Vassart
Complete nucleotide sequence of a putative G protein coupled receptor: RDC8.
Nucleic acids research 1990;18(7):1914.
1990: C Streydio; S Swillens; M Georges; Claude Szpirer; Gilbert Vassart
Structure, evolution and chromosomal localization of the human pregnancy-specific beta 1 glycoprotein gene family.
Genomics 1990;6(4):579-92.
1990: F Javaux; Gilbert Vassart; Daniel Christophe
Nucleotide sequence of a putative transcription factor recognizing the thyroglobulin promoter.
Nucleic acids research 1990;18(5):1301.
1990: J Perret; Y C Shia; R Fries; Gilbert Vassart; M Georges
A polymorphic satellite sequence maps to the pericentric region of the bovine Y chromosome.
Genomics 1990;6(3):482-90.
1990: Michel Georges; M Lathrop; P Hilbert; A Marcotte; A Schwers; S Swillens; Gilbert Vassart; R Hanset
On the use of DNA fingerprints for linkage studies in cattle.
Genomics 1990;6(3):461-74.
1990: Gilbert Vassart; Pascale Cochaux; M Abramowicz
CF screening.
Nature 1990;343(6259):586.
1990: C Streydio; Gilbert Vassart
Expression of human pregnancy specific beta 1 glycoprotein (PSG) genes during placental development.
Biochemical and biophysical research communications 1990;166(3):1265-73.
1990: M J Abramowicz; Gilbert Vassart; D Christophe
Thyroid peroxidase gene promoter confers TSH responsiveness to heterologous reporter genes in transfection experiments.
Biochemical and biophysical research communications 1990;166(3):1257-64.
1990: F Libert; M Parmentier; Carine Maenhaut; A Lefort; C Gérard; J Perret; Jacqueline Van Sande; Jacques E Dumont; Gilbert Vassart
Molecular cloning of a dog thyrotropin (TSH) receptor variant.
Molecular and cellular endocrinology 1990;68(1):R15-7.
1990: Michel Georges; M Lathrop; Y Bouquet; P Hilbert; A Marcotte; A Schwers; J Roupain; Gilbert Vassart; R Hanset
Linkage relationships among 20 genetic markers in cattle. Evidence for linkage between two pairs of blood group systems: B-Z and S-F/V respectively.
Animal genetics 1990;21(2):95-105.
1990: A Lefort; E Passage; F Libert; J Szpirer; Gilbert Vassart; M G Mattei
Localization of human calcyphosine gene (CAPS) to the p13.3 region of chromosome 19 by in situ hybridization.
Cytogenetics and cell genetics 1990;54(3-4):154-5.
1990: F Libert; E Passage; A Lefort; Gilbert Vassart; M G Mattei
Localization of human thyrotropin receptor gene to chromosome region 14q3 by in situ hybridization.
Cytogenetics and cell genetics 1990;54(1-2):82-3.
1990: C M Gérard; A Lefort; Daniel Christophe; F Libert; Jacqueline Van Sande; Jacques E Dumont; Gilbert Vassart
Distinct transcriptional effects of cAMP on 2 thyroid specific genes: thyroperoxidase and thyroglobulin.
Hormone and metabolic research. Supplement series 1990;23():38-43.
1990: M Ludgate; Gilbert Vassart
The molecular genetics of three thyroid autoantigens: thyroglobulin, thyroid peroxidase and the thyrotropin receptor.
Autoimmunity 1990;7(2-3):201-11.
1989: F Libert; A Lefort; C Gerard; M Parmentier; J Perret; Marian Ludgate; Jacques E Dumont; Gilbert Vassart
Cloning, sequencing and expression of the human thyrotropin (TSH) receptor: evidence for binding of autoantibodies.
Biochemical and biophysical research communications 1989;165(3):1250-5.
1989: M Parmentier; F Libert; Carine Maenhaut; A Lefort; C Gérard; J Perret; Jacqueline Van Sande; Jacques E Dumont; Gilbert Vassart
Nucleotide sequence of the dog thyrotropin receptor cDNA.
Nucleic acids research 1989;17(24):10493.
1989: M Parmentier; F Libert; Carine Maenhaut; A Lefort; C Gérard; J Perret; Jacqueline Van Sande; Jacques E Dumont; Gilbert Vassart
Molecular cloning of the thyrotropin receptor.
Science (New York, N.Y.) 1989;246(4937):1620-2.
1989: C M Gérard; A Lefort; Daniel Christophe; F Libert; Jacqueline Van Sande; Jacques E Dumont; Gilbert Vassart
Control of thyroperoxidase and thyroglobulin transcription by cAMP: evidence for distinct regulatory mechanisms.
Molecular endocrinology (Baltimore, Md.) 1989;3(12):2110-8.
1989: Q Dong; M Ludgate; Gilbert Vassart
Towards an antigenic map of human thyroglobulin: identification of ten epitope-bearing sequences within the primary structure of thyroglobulin.
The Journal of endocrinology 1989;122(1):169-76.
1989: Daniel Christophe; C Gérard; Guillermo Juvenal; A Bacolla; E Teugels; C Ledent; Christiane Christophe-Hobertus; Jacques E Dumont; Gilbert Vassart
Identification of a cAMP-responsive region in thyroglobulin gene promoter.
Molecular and cellular endocrinology 1989;64(1):5-18.
1989: Marian Ludgate; Stefano Mariotti; F Libert; C Dinsart; P Piccolo; F Santini; Jean Ruf; Aldo Pinchera; Gilbert Vassart
Antibodies to human thyroid peroxidase in autoimmune thyroid disease: studies with a cloned recombinant complementary deoxyribonucleic acid epitope.
The Journal of clinical endocrinology and metabolism 1989;68(6):1091-6.
1989: F Libert; M Parmentier; A Lefort; C Dinsart; Jacqueline Van Sande; Carine Maenhaut; M J Simons; Jacques E Dumont; Gilbert Vassart
Selective amplification and cloning of four new members of the G protein-coupled receptor family.
Science (New York, N.Y.) 1989;244(4904):569-72.
1989: C Hansen; F Javaux; Guillermo Juvenal; Gilbert Vassart; Daniel Christophe
cAMP-dependent binding of a trans-acting factor to the thyroglobulin promoter.
Biochemical and biophysical research communications 1989;160(2):722-31.
1989: Hennie Bikker; PA Bolhuis; Gilbert Vassart; F Libert; G Massaro; Jan J M de Vijlder
Eco RI RFLP in the human thyroid peroxidase (TPO) gene on chromosome 2.
Human genetics 1989;82(1):95.
1989: G Massaro; F Libert; Gilbert Vassart; C Dinsart
RFLPs detected at 2 pter-p12 with a thyroid peroxidase cDNA probe, TPO3 (McKusick no. 27450).
Nucleic acids research 1989;17(5):2155.
1989: L Mercken; M J Simons; H Brocas; Gilbert Vassart
Alternative splicing may be responsible for heterogeneity of thyroglobulin structure.
Biochimie 1989;71(2):223-6.
1989: A Lefort; R Lecocq; F Libert; Françoise Lamy; S Swillens; Gilbert Vassart; Jacques E Dumont
Cloning and sequencing of a calcium-binding protein regulated by cyclic AMP in the thyroid.
The EMBO journal 1989;8(1):111-6.
1989: P Hilbert; A Marcotte; A Schwers; R Hanset; Gilbert Vassart; Michel Georges
Analysis of genetic variation in the Belgian Blue cattle breed using DNA sequence polymorphism at the growth hormone, low density lipoprotein receptor, alpha-subunit of glycoprotein hormones and thyroglobulin loci.
Animal genetics 1989;20(4):383-93.
1988: C Hansen; C Gerard; Gilbert Vassart; P Stordeur; Daniel Christophe
Thyroid-specific and cAMP-dependent hypersensitive regions in thyroglobulin gene chromatin.
European journal of biochemistry / FEBS 1988;178(2):387-93.
1988: C M Gerard; A Lefort; F Libert; Daniel Christophe; Jacques E Dumont; Gilbert Vassart
Transcriptional regulation of the thyroperoxydase gene by thyrotropin and forskolin.
Molecular and cellular endocrinology 1988;60(2-3):239-42.
1988: Michel Georges; P Hilbert; Anne-Sophie Lequarré; V Leclerc; R Hanset; Gilbert Vassart
Use of DNA bar codes to resolve a canine paternity dispute.
Journal of the American Veterinary Medical Association 1988;193(9):1095-8.
1988: M Parmentier; Gilbert Vassart
HindIII RFLP on chromosome 8 detected with a calbindin 27 kDa cDNA probe, HBSC21.
Nucleic acids research 1988;16(19):9373.
1988: C Streydio; K Lacka; S Swillens; Gilbert Vassart
The human pregnancy-specific beta 1-glycoprotein (PS beta G) and the carcinoembryonic antigen (CEA)-related proteins are members of the same multigene family.
Biochemical and biophysical research communications 1988;154(1):130-7.
1988: P Simon; H Brocas; D Baran; R van Geffel; F Rodesch; Gilbert Vassart
Carrier prediction of cystic fibrosis in 36 families by means of restriction fragment length polymorphism.
European journal of pediatrics 1988;147(2):199-201.
1988: Jan J M de Vijlder; C Dinsart; F Libert; A Geurts van Kessel; Hennie Bikker; PA Bolhuis; Gilbert Vassart
Regional localization of the gene for thyroid peroxidase to human chromosome 2pter----p12.
Cytogenetics and cell genetics 1988;47(3):170-2.
1988: Michel Georges; Anne-Sophie Lequarré; M Castelli; R Hanset; Gilbert Vassart
DNA fingerprinting in domestic animals using four different minisatellite probes.
Cytogenetics and cell genetics 1988;47(3):127-31.
1987: M Parmentier; D E Lawson; Gilbert Vassart
Human 27-kDa calbindin complementary DNA sequence. Evolutionary and functional implications.
European journal of biochemistry / FEBS 1987;170(1-2):207-15.
1987: F Libert; J Ruel; Marian Ludgate; S Swillens; N Alexander; Gilbert Vassart; C Dinsart
Thyroperoxidase, an auto-antigen with a mosaic structure made of nuclear and mitochondrial gene modules.
The EMBO journal 1987;6(13):4193-6.
1987: Michel Georges; P Cochaux; Anne-Sophie Lequarré; M W Young; Gilbert Vassart
DNA fingerprinting in man using a mouse probe related to part of the Drosophila 'Per' gene.
Nucleic acids research 1987;15(17):7193.
1987: F Libert; J Ruel; Marian Ludgate; S Swillens; N Alexander; Gilbert Vassart; C Dinsart
Complete nucleotide sequence of the human thyroperoxidase-microsomal antigen cDNA.
Nucleic acids research 1987;15(16):6735.
1987: Jasmine Parma; Daniel Christophe; V Pohl; Gilbert Vassart
Structural organization of the 5' region of the thyroglobulin gene. Evidence for intron loss and "exonization" during evolution.
Journal of molecular biology 1987;196(4):769-79.
1987: G de Martynoff; V Pohl; L Mercken; G J van Ommen; Gilbert Vassart
Structural organization of the bovine thyroglobulin gene and of its 5'-flanking region.
European journal of biochemistry / FEBS 1987;164(3):591-9.
1987: M H Ricketts; M J Simons; Jasmine Parma; L Mercken; Q Dong; Gilbert Vassart
A nonsense mutation causes hereditary goitre in the Afrikander cattle and unmasks alternative splicing of thyroglobulin transcripts.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(10):3181-4.
1987: Gilbert Vassart; Michel Georges; R Monsieur; H Brocas; Anne-Sophie Lequarré; D Christophe
A sequence in M13 phage detects hypervariable minisatellites in human and animal DNA.
Science (New York, N.Y.) 1987;235(4789):683-4.
1987: Gilbert Vassart; H Brocas; Daniel Christophe; G de Martynoff; C Gérard; C Hansen; Guillermo Juvenal; M Ludgate; L Mercken; Jasmine Parma
Normal and defective expression of the thyroglobulin gene.
Hormone research 1987;26(1-4):8-11.
1987: H Brocas; Michel Georges; D Christophe; R Monsieur; Anne-Sophie Lequarré; Gilbert Vassart
[A family of hypervariable minisatellites detected by means of a sequence derived from phage M 13].
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1987;304(3):67-9.
1987: Michel Georges; Anne-Sophie Lequarré; R Hanset; Gilbert Vassart
Genetic variation of the bovine thyroglobulin gene studied at the DNA level.
Animal genetics 1987;18(1):41-50.
1986: B Cabrer; H Brocas; A Perez-Castillo; V Pohl; J J Navas; Héctor M Targovnik; J A Centenera; Gilbert Vassart
Normal level of thyroglobulin messenger ribonucleic acid in a human congenital goiter with thyroglobulin deficiency.
The Journal of clinical endocrinology and metabolism 1986;63(4):931-40.
1986: M Ludgate; S Swillens; L Mercken; Gilbert Vassart
Homology between thyroglobulin and acetylcholinesterase: an explanation for pathogenesis of Graves' ophthalmopathy?
Lancet 1986;2(8500):219-20.
1986: S Swillens; M Ludgate; L Mercken; J E Dumont; Gilbert Vassart
Analysis of sequence and structure homologies between thyroglobulin and acetylcholinesterase: possible functional and clinical significance.
Biochemical and biophysical research communications 1986;137(1):142-8.
1985: B Van Heuverswyn; A Leriche; J Van Sande; J E Dumont; Gilbert Vassart
Transcriptional control of thyroglobulin gene expression by cyclic AMP.
FEBS letters 1985;188(2):192-6.
1985: L Mercken; M J Simons; S Swillens; M Massaer; Gilbert Vassart
Primary structure of bovine thyroglobulin deduced from the sequence of its 8,431-base complementary DNA.
Nature 1985;316(6029):647-51.
1985: Daniel Christophe; B Cabrer; A Bacolla; Héctor M Targovnik; V Pohl; Gilbert Vassart
An unusually long poly(purine)-poly(pyrimidine) sequence is located upstream from the human thyroglobulin gene.
Nucleic acids research 1985;13(14):5127-44.
1985: M Rabin; Peter Barker; F H Ruddle; H Brocas; Héctor M Targovnik; Gilbert Vassart
Proximity of thyroglobulin and c-myc genes on human chromosome 8.
Somatic cell and molecular genetics 1985;11(4):397-402.
1985: Gilbert Vassart; A Bacolla; H Brocas; Daniel Christophe; G de Martynoff; A Leriche; L Mercken; Jasmine Parma; V Pohl; Héctor M Targovnik
Structure, expression and regulation of the thyroglobulin gene.
Molecular and cellular endocrinology 1985;40(2-3):89-97.
1985: M H Ricketts; V Pohl; G de Martynoff; Charles D Boyd; A J Bester; Pieter van Jaarsveld; Gilbert Vassart
Defective splicing of thyroglobulin gene transcripts in the congenital goitre of the Afrikander cattle.
The EMBO journal 1985;4(3):731-7.
1985: L Mercken; M J Simons; G De Martynoff; S Swillens; Gilbert Vassart
Presence of hormonogenic and repetitive domains in the first 930 amino acids of bovine thyroglobulin as deduced from the cDNA sequence.
European journal of biochemistry / FEBS 1985;147(1):59-64.
1984: L Mercken; M Massaer; M J Simons; S Swillens; Gilbert Vassart
Identification of hormonogenic domains in the carboxyl terminal region of bovine thyroglobulin.
Biochemical and biophysical research communications 1984;125(3):961-6.
1984: B Van Heuverswyn; C Streydio; H Brocas; S Refetoff; J Dumont; Gilbert Vassart
Thyrotropin controls transcription of the thyroglobulin gene.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(19):5941-5.
1984: Héctor M Targovnik; V Pohl; Daniel Christophe; B Cabrer; H Brocas; Gilbert Vassart
Structural organization of the 5' region of the human thyroglobulin gene.
European journal of biochemistry / FEBS 1984;141(2):271-7.
1982: L Mercken; M J Simons; Gilbert Vassart
The 5'-end of bovine thyroglobulin mRNA encodes a hormonogenic peptide.
FEBS letters 1982;149(2):285-7.
1982: Gilbert Vassart; H Brocas; Daniel Christophe; G de Martynoff; A Leriche; L Mercken; V Pohl; B Van Heuverswyn
[Structure and expression of thyroglobulin gene].
Annales d'endocrinologie 1982;43(5):404-14.
1982: Daniel Christophe; V Pohl; B Van Heuverswijn; G De Martynoff; H Brocas; J E Dumont; J L Pasteels; Gilbert Vassart
Isolation and characterization of a fragment of rat thyroglobulin gene.
Biochemical and biophysical research communications 1982;105(3):1166-75.
1982: Daniel Christophe; L Mercken; H Brocas; V Pohl; Gilbert Vassart
Molecular cloning of the 8000-base thyroglobulin structural gene.
European journal of biochemistry / FEBS 1982;122(3):461-9.
1982: H Brocas; Daniel Christophe; V Pohl; Gilbert Vassart
Cloning of human thyroglobulin complementary DNA.
FEBS letters 1982;137(2):189-92.
1981: Jan J M de Vijlder; G J van Ommen; W F van Voorthuizen; C A Koch; A C Arnberg; Gilbert Vassart; C Dinsart; R A Flavell
Nonfunctional thyroglobulin messenger RNA in goats with hereditary congenital goiter.
Journal of molecular and applied genetics 1981;1(1):51-9.
1980: H Brocas; Daniel Christophe; B Van Heuverswijn; N Scherberg; Gilbert Vassart
Molecular cloning of Pst I fragments from rat double stranded thyroglobulin complementary DNA.
Biochemical and biophysical research communications 1980;96(4):1785-92.
1980: Daniel Christophe; H Brocas; F Gannon; G de Martynoff; E Pays; Gilbert Vassart
Molecular cloning of bovine thyroglobulin complementary DNA. Characterization of 2500-base-pair and 1900-base-pair fragments.
European journal of biochemistry / FEBS 1980;111(2):419-23.
1980: G de Martynoff; E Pays; Gilbert Vassart
Synthesis of a full length DNA complementary to thyroglobulin 33 S messenger RNA.
Biochemical and biophysical research communications 1980;93(3):645-53.
1980: A J Van Herle; B Van Heuverswyn; Gilbert Vassart
[Dosage of serum thyroglobulin in clinical practice (author's transl)].
Revue médicale de Bruxelles 1980;1(1):5-8.