Philip Aisen

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Dadachova Ekaterina; Bryan Ruth A; Howell Robertha C; Schweitzer Andrew D; Aisen Philip; Nosanchuk Joshua D; Casadevall Arturo
The radioprotective properties of fungal melanin are a function of its chemical composition, stable radical presence and spatial arrangement.
Cheng Yifan; Wolf Elmar; Larvie Mykol; Zak Olga; Aisen Philip; Grigorieff Nikolaus; Harrison Stephen C; Walz Thomas
Single particle reconstructions of the transferrin-transferrin receptor complex obtained with different specimen preparation techniques.
Cheng Yifan; Zak Olga; Aisen Philip; Harrison Stephen C; Walz Thomas
Single particle reconstruction of the human apo-transferrin-transferrin receptor complex.

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2008: Dadachova Ekaterina; Bryan Ruth A; Howell Robertha C; Schweitzer Andrew D; Aisen Philip; Nosanchuk Joshua D; Casadevall Arturo
The radioprotective properties of fungal melanin are a function of its chemical composition, stable radical presence and spatial arrangement.
Pigment cell & melanoma research 2008;21(2):192-9.
2006: Cheng Yifan; Wolf Elmar; Larvie Mykol; Zak Olga; Aisen Philip; Grigorieff Nikolaus; Harrison Stephen C; Walz Thomas
Single particle reconstructions of the transferrin-transferrin receptor complex obtained with different specimen preparation techniques.
Journal of molecular biology 2006;355(5):1048-65.
2005: Cheng Yifan; Zak Olga; Aisen Philip; Harrison Stephen C; Walz Thomas
Single particle reconstruction of the human apo-transferrin-transferrin receptor complex.
Journal of structural biology 2005;152(3):204-10.
2005: Xu Guozhong; Liu Rutao; Zak Olga; Aisen Philip; Chance Mark R
Structural allostery and binding of the transferrin*receptor complex.
Molecular & cellular proteomics : MCP 2005;4(12):1959-67.
2004: Aisen Philip
Transferrin receptor 1.
The international journal of biochemistry & cell biology 2004;36(11):2137-43.
2004: Cheng Yifan; Zak Olga; Aisen Philip; Harrison Stephen C; Walz Thomas
Structure of the human transferrin receptor-transferrin complex.
Cell 2004;116(4):565-76.
2004: Ikuta Katsuya; Zak Olga; Aisen Philip
Recycling, degradation and sensitivity to the synergistic anion of transferrin in the receptor-independent route of iron uptake by human hepatoma (HuH-7) cells.
The international journal of biochemistry & cell biology 2004;36(2):340-52.
2004: Dhungana Suraj; Taboy Céline H; Zak Olga; Larvie Mykol; Crumbliss Alvin L; Aisen Philip
Redox properties of human transferrin bound to its receptor.
Biochemistry 2004;43(1):205-9.
2003: Liu Rutao; Guan Jing-Qu; Zak Olga; Aisen Philip; Chance Mark R
Structural reorganization of the transferrin C-lobe and transferrin receptor upon complex formation: the C-lobe binds to the receptor helical domain.
Biochemistry 2003;42(43):12447-54.
2003: Zak Olga; Aisen Philip
Iron release from transferrin, its C-lobe, and their complexes with transferrin receptor: presence of N-lobe accelerates release from C-lobe at endosomal pH.
Biochemistry 2003;42(42):12330-4.
2003: Dhungana Suraj; Taboy Celine H; Anderson Damon S; Vaughan Kevin G; Aisen Philip; Mietzner Timothy A; Crumbliss Alvin L
The influence of the synergistic anion on iron chelation by ferric binding protein, a bacterial transferrin.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):3659-64.
2003: Navati Mahantesh S; Samuni Uri; Aisen Philip; Friedman Joel M
Binding and release of iron by gel-encapsulated human transferrin: evidence for a conformational search.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):3832-7.
2003: Zak Olga; Aisen Philip
A poly-His tag method for obtaining the C-terminal lobe of human transferrin.
Protein expression and purification 2003;28(1):120-4.
2002: Zak Olga; Ikuta Katsuya; Aisen Philip
The synergistic anion-binding sites of human transferrin: chemical and physiological effects of site-directed mutagenesis.
Biochemistry 2002;41(23):7416-23.
2002: Zak Olga; Aisen Philip
A new method for obtaining human transferrin C-lobe in the native conformation: preparation and properties.
Biochemistry 2002;41(5):1647-53.
2001: Aisen P; Enns C; Wessling-Resnick M
Chemistry and biology of eukaryotic iron metabolism.
The international journal of biochemistry & cell biology 2001;33(10):940-59.
2001: Taboy C H; Vaughan K G; Mietzner T A; Aisen P; Crumbliss A L
Fe3+ coordination and redox properties of a bacterial transferrin.
The Journal of biological chemistry 2001;276(4):2719-24.
1999: Aisen P; Wessling-Resnick M; Leibold E A
Iron metabolism.
Current opinion in chemical biology 1999;3(2):200-6.
1998: Aisen P
Transferrin, the transferrin receptor, and the uptake of iron by cells.
Metal ions in biological systems 1998;35():585-631.
1997: Zak O; Tam B; MacGillivray R T; Aisen P
A kinetically active site in the C-lobe of human transferrin.
Biochemistry 1997;36(36):11036-43.
1996: Trinder D; Zak O; Aisen P
Transferrin receptor-independent uptake of differic transferrin by human hepatoma cells with antisense inhibition of receptor expression.
Hepatology (Baltimore, Md.) 1996;23(6):1512-20.
1995: Zak O; Aisen P; Crawley J B; Joannou C L; Patel K J; Rafiq M; Evans R W
Iron release from recombinant N-lobe and mutants of human transferrin.
Biochemistry 1995;34(44):14428-34.
1995: Thorstensen K; Trinder D; Zak O; Aisen P
Uptake of iron from N-terminal half-transferrin by isolated rat hepatocytes. Evidence of transferrin-receptor-independent iron uptake.
European journal of biochemistry / FEBS 1995;232(1):129-33.
1994: Zak O; Trinder D; Aisen P
Primary receptor-recognition site of human transferrin is in the C-terminal lobe.
The Journal of biological chemistry 1994;269(10):7110-4.
1994: Aisen P
The transferrin receptor and the release of iron from transferrin.
Advances in experimental medicine and biology 1994;356():31-40.
1993: Egan T J; Zak O; Aisen P
The anion requirement for iron release from transferrin is preserved in the receptor-transferrin complex.
Biochemistry 1993;32(32):8162-7.
1993: Sasaki K; Zak O; Aisen P
Antisense suppression of transferrin receptor gene expression in a human hepatoma cell (HuH-7) line.
American journal of hematology 1993;42(1):74-80.
1992: Egan T J; Barthakur S R; Aisen P
Catalysis of the Haber-Weiss reaction by iron-diethylenetriaminepentaacetate.
Journal of inorganic biochemistry 1992;48(4):241-9.
1992: Bali P K; Aisen P
Receptor-induced switch in site-site cooperativity during iron release by transferrin.
Biochemistry 1992;31(16):3963-7.
1992: Aisen P
Entry of iron into cells: a new role for the transferrin receptor in modulating iron release from transferrin.
Annals of neurology 1992;32 Suppl():S62-8.
1991: Bali P K; Aisen P
Receptor-modulated iron release from transferrin: differential effects on N- and C-terminal sites.
Biochemistry 1991;30(41):9947-52.
1991: Bali P K; Zak O; Aisen P
A new role for the transferrin receptor in the release of iron from transferrin.
Biochemistry 1991;30(2):324-8.
1990: Thorstensen K; Aisen P
Release of iron from diferric transferrin in the presence of rat liver plasma membranes: no evidence of a plasma membrane diferric transferrin reductase.
Biochimica et biophysica acta 1990;1052(1):29-35.
1990: Zak O; Aisen P
Evidence for functional differences between the two sites of rabbit transferrin: effects of serum and carbon dioxide.
Biochimica et biophysica acta 1990;1052(1):24-8.
1989: Sibille J C; Ciriolo M; Kondo H; Crichton R R; Aisen P
Subcellular localization of ferritin and iron taken up by rat hepatocytes.
The Biochemical journal 1989;262(2):685-8.
1989: Chan J; Fujiwara T; Brennan P; McNeil M; Turco S J; Sibille J C; Snapper M; Aisen P; Bloom B R
Microbial glycolipids: possible virulence factors that scavenge oxygen radicals.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(7):2453-7.
1989: Osterloh K; Aisen P
Pathways in the binding and uptake of ferritin by hepatocytes.
Biochimica et biophysica acta 1989;1011(1):40-5.
1989: Sibille J C; Kondo H; Aisen P
Uptake of ferritin and iron bound to ferritin by rat hepatocytes: modulation by apotransferrin, iron chelators and chloroquine.
Biochimica et biophysica acta 1989;1010(2):204-9.
1988: Doi K; McCracken J; Peisach J; Aisen P
The binding of molybdate to uteroferrin. Hyperfine interactions of the binuclear center with 95Mo, 1H, and 2H.
The Journal of biological chemistry 1988;263(12):5757-63.
1988: Sibille J C; Kondo H; Aisen P
Interactions between isolated hepatocytes and Kupffer cells in iron metabolism: a possible role for ferritin as an iron carrier protein.
Hepatology (Baltimore, Md.) 1988;8(2):296-301.
1988: Zak O; Aisen P
Spectroscopic and thermodynamic studies on the binding of gadolinium(III) to human serum transferrin.
Biochemistry 1988;27(3):1075-80.
1988: Kondo H; Saito K; Grasso J P; Aisen P
Iron metabolism in the erythrophagocytosing Kupffer cell.
Hepatology (Baltimore, Md.) 1988;8(1):32-8.
1988: Aisen P
Iron metabolism in isolated liver cells.
Annals of the New York Academy of Sciences 1988;526():93-100.
1987: Sibille J C; Doi K; Aisen P
Hydroxyl radical formation and iron-binding proteins. Stimulation by the purple acid phosphatases.
The Journal of biological chemistry 1987;262(1):59-62.

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Philip Aisen

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