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DM Bowen
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67
Francis, Paul
29
Neary, David
12
Esiri, Margaret
12
Palmer, Alan
11
Mann, D M A
8
Pearson, Ronald Carl Alan
8
Snowden, Julie
8
Wilcock, Gordon
2
Harrison, Paul
2
Heath, Paul
2
Blass, John
2
Chessell, IP
1
DeKosky, Steven
1
Baines, Paul
1
Marion, Donald
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All Publications
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2008: Bowen D M; Procter A W; Mann D M A; Snowden J S; Esiri M M; Neary D; Francis P T
Imbalance of a serotonergic system in frontotemporal dementia: implication for pharmacotherapy.
Psychopharmacology 2008;196(4):603-10.
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1998: Webster M T; Pearce B R; Bowen D M; Francis P T
The effects of perturbed energy metabolism on the processing of amyloid precursor protein in PC12 cells.
Journal of neural transmission (Vienna, Austria : 1996) 1998;105(8-9):839-53.
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1997: Heath P R; Chessell I P; Sanders M W; Francis P T; Bowen D M; Pearson R C
Neuronal degeneration by suicide transport following injection of volkensin into rat cerebral cortex.
Experimental neurology 1997;147(1):192-203.
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1997: Francis P T; Chessell I P; Bowen D M
New approaches to imaging based on effects of neurotoxins.
Dementia and geriatric cognitive disorders 1997;8(2):117-22.
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1996: Chen C P; Alder J T; Bowen D M; Esiri M M; McDonald B; Hope T; Jobst K A; Francis P T
Presynaptic serotonergic markers in community-acquired cases of Alzheimer's disease: correlations with depression and neuroleptic medication.
Journal of neurochemistry 1996;66(4):1592-8.
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1995: Chessell I P; Francis P T; Bowen D M
Changes in cortical nicotinic acetylcholine receptor numbers following unilateral destruction of pyramidal neurones by intrastriatal volkensin injection.
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration 1995;4(4):415-24.
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1995: Qume M; Misra A; Zeman S; Boddy J L; Cross A J; Francis P T; Procter A W; Mann D M; Bowen D M
Non-serotonergic profiles of lobar atrophies.
Biochemical Society transactions 1995;23(4):601S.
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1995: Qume M; Misra A; Zeman S; Muthu J; Cross A J; Francis P T; Procter A W; Neary D; Bowen D M
Serotonergic profiles of lobar atrophies.
Biochemical Society transactions 1995;23(4):600S.
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1995: Dijk S N; Francis P T; Stratmann G C; Bowen D M
Cholinomimetics increase glutamate outflow via an action on the corticostriatal pathway: implications for Alzheimer's disease.
Journal of neurochemistry 1995;65(5):2165-9.
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1995: Webster M T; Groome N; Francis P T; Pearce B R; Sherriff F E; Thinakaran G; Felsenstein K M; Wasco W; Tanzi R E; Bowen D M
A novel protein, amyloid precursor-like protein 2, is present in human brain, cerebrospinal fluid and conditioned media.
The Biochemical journal 1995;310 ( Pt 1)():95-9.
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1995: Dijk S N; Francis P T; Stratmann G C; Bowen D M
NMDA-induced glutamate and aspartate release from rat cortical pyramidal neurones: evidence for modulation by a 5-HT1A antagonist.
British journal of pharmacology 1995;115(7):1169-74.
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1995: Alder J T; Chessell I P; Bowen D M
A neurochemical approach for studying response to acetylcholine in Alzheimer's disease.
Neurochemical research 1995;20(7):769-71.
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1994: Palmer A M; Marion D W; Botscheller M L; Bowen D M; DeKosky S T
Increased transmitter amino acid concentration in human ventricular CSF after brain trauma.
Neuroreport 1994;6(1):153-6.
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1994: Webster M T; Francis P T; Procter A W; Stratmann G C; Doshi R; Mann D M; Bowen D M
Postmortem brains reveal similar but not identical amyloid precursor protein-like immunoreactivity in Alzheimer compared with other dementias.
Brain research 1994;644(2):347-51.
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1994: Bowen D M; Francis P T; Chessell I P; Webster M T
Neurotransmission--the link integrating Alzheimer research?
Trends in neurosciences 1994;17(4):149-50.
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1994: Stratmann G C; Webster M T; Francis P T; Procter A W; Bowen D M
Brain membrane serine protease activity in human cortex compared with rat: implication for Alzheimer's disease.
Dementia (Basel, Switzerland) 1994;5(2):62-8.
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1994: Harrison P J; Barton A J; Procter A W; Bowen D M; Pearson R C
The effects of Alzheimer's disease, other dementias, and premortem course on beta-amyloid precursor protein messenger RNA in frontal cortex.
Journal of neurochemistry 1994;62(2):635-44.
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1994: Francis P T; Bowen D M
Neuronal pathology in relation to molecular biology and treatment of Alzheimer's disease.
Molecular and cell biology of human diseases series 1994;4():25-54.
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1994: Chessell I P; Francis P T; Webster M T; Procter A W; Heath P R; Pearson R C; Bowen D M
An aspect of Alzheimer neuropathology after suicide transport damage.
Journal of neural transmission. Supplementum 1994;44():231-43.
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1993: Chessell I P; Francis P T; Pangalos M N; Pearson R C; Bowen D M
Localisation of muscarinic (m1) and other neurotransmitter receptors on corticofugal-projecting pyramidal neurones.
Brain research 1993;632(1-2):86-94.
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1993: Francis P T; Webster M T; Chessell I P; Holmes C; Stratmann G C; Procter A W; Cross A J; Green A R; Bowen D M
Neurotransmitters and second messengers in aging and Alzheimer's disease.
Annals of the New York Academy of Sciences 1993;695():19-26.
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1993: Stratmann G C; Webster M T; Bhogal G; Francis P T; Bowen D M
Protease "Clipsin" activity and beta-amyloid precursor protein degradation by Alzheimer brain.
Biochemical Society transactions 1993;21 ( Pt 3)(3):241S.
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1993: Chessell I P; Francis P T; Bowen D M
A cortical pyramidal neurone neurotransmitter receptor that may affect beta-amyloid precursor protein.
Biochemical Society transactions 1993;21 ( Pt 3)(3):240S.
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1993: Webster M T; Vekrellis K; Francis P T; Pearce B R; Bowen D M
Factors affecting the beta-amyloid precursor in PC12 cells.
Biochemical Society transactions 1993;21 ( Pt 3)(3):239S.
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1993: Holmes C; Webster M T; Procter A W; Francis P T; Bowen D M
Relationship between beta-amyloid precursor protein, pyramidal neurones and astrocytes in human neocortex.
Biochemical Society transactions 1993;21 ( Pt 3)(3):238S.
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1993: Clarke N A; Procter A W; Webster M T; Francis P T; Hodgkiss A D; Bowen D M
Effect of Li+ therapy and site of origin on cerebrospinal fluid beta-amyloid precursor protein derivatives.
Biochemical Society transactions 1993;21 ( Pt 3)(3):242S.
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1993: Francis P T; Sims N R; Procter A W; Bowen D M
Cortical pyramidal neurone loss may cause glutamatergic hypoactivity and cognitive impairment in Alzheimer's disease: investigative and therapeutic perspectives.
Journal of neurochemistry 1993;60(5):1589-604.
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1993: Francis P T; Holmes C; Webster M T; Stratmann G C; Procter A W; Bowen D M
Preliminary neurochemical findings in non-Alzheimer dementia due to lobar atrophy.
Dementia (Basel, Switzerland) 1993;4(3-4):172-7.
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1993: Francis P T; Webster M T; Procter A W; Clarke N A; Bowen D M; Doshi R; Mann D M; Neary D
Soluble beta-amyloid precursor protein and pyramidal neuron loss.
Lancet 1993;341(8842):431.
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1993: Francis P T; Pangalos M N; Stephens P H; Bartlett J R; Bridges P K; Malizia A L; Neary D; Procter A W; Thomas D J; Bowen D M
Antemortem measurements of neurotransmission: possible implications for pharmacotherapy of Alzheimer's disease and depression.
Journal of neurology, neurosurgery, and psychiatry 1993;56(1):80-4.
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1993: Bowen D M; Francis P T; Pangalos M N; Chessell I P
Neurotransmitter receptors of rat cortical pyramidal neurones: implications for in vivo imaging and therapy.
Journal of reproduction and fertility. Supplement 1993;46():131-43.
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1992: Francis P T; Pangalos M N; Bowen D M
Animal and drug modelling for Alzheimer synaptic pathology.
Progress in neurobiology 1992;39(5):517-45.
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1992: Pangalos M N; Francis P T; Foster A C; Pearson R C; Middlemiss D N; Bowen D M
NMDA receptors assessed by autoradiography with [3H]L-689,560 are present but not enriched on corticofugal-projecting pyramidal neurones.
Brain research 1992;596(1-2):223-30.
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1992: Bowen D; Francis P; Sims N; Cross A
Protection from dementia.
Science (New York, N.Y.) 1992;258(5087):1422-3.
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1992: Bowen D M; Francis P T; Sims N R
beta-Amyloid increased neuronal susceptibility to injury by glucose deprivation.
Neuroreport 1992;3(9):733-4.
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1992: Procter A W; Francis P T; Stratmann G C; Bowen D M
Serotonergic pathology is not widespread in Alzheimer patients without prominent aggressive symptoms.
Neurochemical research 1992;17(9):917-22.
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1992: Stratmann G C; Webster M T; Francis P T; Procter A W; Bowen D M
Protease 'Clipsin' extract activity reflects demographic characteristics of human brain.
Neuroscience letters 1992;143(1-2):43-7.
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1992: Bowen D M; Francis P T; Procter A W; Halliwell J V; Mann D M; Neary D
Treatment strategy for the corticocortical neuron pathology of Alzheimer's disease.
Annals of neurology 1992;32(1):112.
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1992: Francis P T; Pangalos M N; Pearson R C; Middlemiss D N; Stratmann G C; Bowen D M
5-Hydroxytryptamine1A but not 5-hydroxytryptamine2 receptors are enriched on neocortical pyramidal neurones destroyed by intrastriatal volkensin.
The Journal of pharmacology and experimental therapeutics 1992;261(3):1273-81.
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1992: Bowen D M
Merging MIS functions.
Health systems review 1992;25(3):47-8.
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1992: Pangalos M N; Malizia A L; Francis P T; Lowe S L; Bertolucci P H; Procter A W; Bridges P K; Bartlett J R; Bowen D M
Effect of psychotropic drugs on excitatory amino acids in patients undergoing psychosurgery for depression.
The British journal of psychiatry : the journal of mental science 1992;160():638-42.
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1992: Bowen D M; Francis P T; Procter A W; Young A B
Treatment of Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 1992;55(4):328.
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1992: Bowen D M; Francis P T; Pangalos M N; Stephens P H; Procter A W; Chessell I P
'Traditional' pharmacotherapy may succeed in Alzheimer's disease.
Trends in neurosciences 1992;15(3):84-5.
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1992: Bowen D M; Francis P T; Pangalos M N; Stephens P H; Procter A W
Treatment strategies for Alzheimer's disease.
Lancet 1992;339(8785):132-3.
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1991: Chessell I P; Procter A W; Francis P T; Bowen D M
D-cycloserine, a putative cognitive enhancer, facilitates activation of the N-methyl-D-aspartate receptor-ionophore complex in Alzheimer brain.
Brain research 1991;565(2):345-8.
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1991: Pangalos M N; Francis P T; Pearson R C; Middlemiss D N; Bowen D M
Destruction of a sub-population of cortical neurones by suicide transport of volkensin, a lectin from Adenia volkensii.
Journal of neuroscience methods 1991;40(1):17-29.
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1991: Wilson K; Bowen D; Francis P; Tyrrell P
Effect of central cholinergic stimulation on regional cerebral blood flow in Alzheimer's disease.
The British journal of psychiatry : the journal of mental science 1991;158():558-62.
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1991: Steele J E; Robinson T N; Cross A J; Bowen D M; Green A R
A comparison of [3H]MK-801 and N-[1-(2-thienyl)cyclohexyl]-3,4-[3H]piperidine binding to the N-methyl-D-aspartate receptor complex in human brain.
Journal of neurochemistry 1991;56(4):1248-54.
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1991: Harrison P J; Procter A W; Barton A J; Lowe S L; Najlerahim A; Bertolucci P H; Bowen D M; Pearson R C
Terminal coma affects messenger RNA detection in post mortem human temporal cortex.
Brain research. Molecular brain research 1991;9(1-2):161-4.
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1991: Procter A W; Stratmann G C; Francis P T; Lowe S L; Bertolucci P H; Bowen D M
Characterisation of the glycine modulatory site of the N-methyl-D-aspartate receptor-ionophore complex in human brain.
Journal of neurochemistry 1991;56(1):299-310.
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1991: Francis P T; Procter A W; Bowen D M
A glycine site as therapeutic target.
Annals of the New York Academy of Sciences 1991;640():184-8.
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1990: Francis P T; Lowe S L; Bowen D M; Jefferys J G
Lack of change in neurochemical markers during the postepileptic phase of intrahippocampal tetanus toxin syndrome in rats.
Epilepsia 1990;31(6):697-701.
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1990: Steele J E; Bowen D M; Francis P T; Green A R; Cross A J
Spermidine enhancement of [3H]MK-801 binding to the NMDA receptor complex in human cortical membranes.
European journal of pharmacology 1990;189(2-3):195-200.
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1990: Bowen D M
Treatment of Alzheimer's disease. Molecular pathology versus neurotransmitter-based therapy.
The British journal of psychiatry : the journal of mental science 1990;157():327-30.
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1990: Lowe S L; Bowen D M
Glutamic acid concentration in brains of patients with Alzheimer's disease.
Biochemical Society transactions 1990;18(3):443-4.
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1990: Najlerahim A; Francis P T; Bowen D M
Age-related alteration in excitatory amino acid neurotransmission in rat brain.
Neurobiology of aging 1990;11(2):155-8.
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1990: Esiri M M; Pearson R C; Steele J E; Bowen D M; Powell T P
A quantitative study of the neurofibrillary tangles and the choline acetyltransferase activity in the cerebral cortex and the amygdala in Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 1990;53(2):161-5.
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1990: Palmer A M; Steele J E; Lowe S L; Bowen D M
Influence of tetrahydro-9-aminoacridine on excitatory amino acid release.
Clinical neuropharmacology 1990;13(1):58-66.
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1990: Bowen D
The cholinergic system and the excitatory amino acids in Alzheimer's disease.
Acta neurologica Scandinavica. Supplementum 1990;129():15-6.
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1990: Procter A W; Francis P T; Lowe S L; Pangalos M N; Steele J E; Bowen D M
Clinical correlations of the neurobiological changes of aging.
Annales de médecine interne 1990;141 Suppl 1():3-6.
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1990: Lowe S L; Bowen D M; Francis P T; Neary D
Ante mortem cerebral amino acid concentrations indicate selective degeneration of glutamate-enriched neurons in Alzheimer's disease.
Neuroscience 1990;38(3):571-7.
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1990: Bowen D M; Steele J E; Lowe S L; Palmer A M
Tacrine in relation to amino acid transmitters in Alzheimer's disease.
Advances in neurology 1990;51():91-6.
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1990: Baines P; Bowen D; Jacobs A
Clonal growth of haemopoietic progenitor cells from myelodysplastic marrow in response to recombinant haemopoietins.
Leukemia research 1990;14(3):247-53.
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1989: Bowen D M; Najlerahim A; Procter A W; Francis P T; Murphy E
Circumscribed changes of the cerebral cortex in neuropsychiatric disorders of later life.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(23):9504-8.
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1989: Metcalfe T; Bowen D M; Muller D P
Vitamin E concentrations in human brain of patients with Alzheimer's disease, fetuses with Down's syndrome, centenarians, and controls.
Neurochemical research 1989;14(12):1209-12.
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1989: Francis P T; Bowen D M
Tacrine, a drug with therapeutic potential for dementia: post-mortem biochemical evidence.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1989;16(4 Suppl):504-10.
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1989: Steele J E; Palmer A M; Stratmann G C; Bowen D M
The N-methyl-D-aspartate receptor complex in Alzheimer's disease: reduced regulation by glycine but not zinc.
Brain research 1989;500(1-2):369-73.
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1989: Bowen D M; Francis P T; Lowe S L; Pangalos M N; Procter A W; Steele J E
Pyramidal neuron loss and "glycine-site therapy": a need for an animal model and study in late-life depression.
Neurobiology of aging 1989;10(5):616-8; discussion 618-20.
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1989: Procter A W; Wong E H; Stratmann G C; Lowe S L; Bowen D M
Reduced glycine stimulation of [3H]MK-801 binding in Alzheimer's disease.
Journal of neurochemistry 1989;53(3):698-704.
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1989: Cross A J; Stirling J M; Robinson T N; Bowen D M; Francis P T; Green A R
The modulation by chlormethiazole of the GABAA-receptor complex in rat brain.
British journal of pharmacology 1989;98(1):284-90.
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1989: Francis P T; Poynton A; Lowe S L; Najlerahim A; Bridges P K; Bartlett J R; Procter A W; Bruton C J; Bowen D M
Brain amino acid concentrations and Ca2+-dependent release in intractable depression assessed antemortem.
Brain research 1989;494(2):315-24.
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1989: Procter A W; Stirling J M; Stratmann G C; Cross A J; Bowen D M
Loss of glycine-dependent radioligand binding to the N-methyl-D-aspartate-phencyclidine receptor complex in patients with Alzheimer's disease.
Neuroscience letters 1989;101(1):62-6.
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1989: Palmer A M; Hutson P H; Lowe S L; Bowen D M
Extracellular concentrations of aspartate and glutamate in rat neostriatum following chemical stimulation of frontal cortex.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1989;75(3):659-63.
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1988: Lowe S L; Francis P T; Procter A W; Palmer A M; Davison A N; Bowen D M
Gamma-aminobutyric acid concentration in brain tissue at two stages of Alzheimer's disease.
Brain : a journal of neurology 1988;111 ( Pt 4)():785-99.
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1988: Palmer A M; Lowe S L; Francis P T; Bowen D M
Are post-mortem biochemical studies of human brain worthwhile?
Biochemical Society transactions 1988;16(4):472-5.
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1988: Tham A; Sparring K; Bowen D; Wetterberg L; Sara V R
Insulin-like growth factors and somatomedin B in the cerebrospinal fluid of patients with dementia of the Alzheimer type.
Acta psychiatrica Scandinavica 1988;77(6):719-23.
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1988: Wilcock G K; Esiri M M; Bowen D M; Hughes A O
The differential involvement of subcortical nuclei in senile dementia of Alzheimer's type.
Journal of neurology, neurosurgery, and psychiatry 1988;51(6):842-9.
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1988: Palmer A M; Stratmann G C; Procter A W; Bowen D M
Possible neurotransmitter basis of behavioral changes in Alzheimer's disease.
Annals of neurology 1988;23(6):616-20.
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1988: Procter A W; Bowen D M
beta-Carbolines for Alzheimer's disease?--more evidence, a test of efficacy and some precautions.
Trends in neurosciences 1988;11(5):208-9.
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1988: Najlerahim A; Bowen D M
Biochemical measurements in Alzheimer's disease reveal a necessity for improved neuroimaging techniques to study metabolism.
The Biochemical journal 1988;251(1):305-8.
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1988: Procter A W; Lowe S L; Palmer A M; Francis P T; Esiri M M; Stratmann G C; Najlerahim A; Patel A J; Hunt A; Bowen D M
Topographical distribution of neurochemical changes in Alzheimer's disease.
Journal of the neurological sciences 1988;84(2-3):125-40.
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1988: Procter A W; Palmer A M; Francis P T; Lowe S L; Neary D; Murphy E; Doshi R; Bowen D M
Evidence of glutamatergic denervation and possible abnormal metabolism in Alzheimer's disease.
Journal of neurochemistry 1988;50(3):790-802.
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1988: Najlerahim A; Bowen D M
Regional weight loss of the cerebral cortex and some subcortical nuclei in senile dementia of the Alzheimer type.
Acta neuropathologica 1988;75(5):509-12.
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1987: Sims N R; Finegan J M; Blass J P; Bowen D M; Neary D
Mitochondrial function in brain tissue in primary degenerative dementia.
Brain research 1987;436(1):30-8.
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1987: Appleyard M E; Smith A D; Berman P; Wilcock G K; Esiri M M; Neary D; Bowen D M
Cholinesterase activities in cerebrospinal fluid of patients with senile dementia of Alzheimer type.
Brain : a journal of neurology 1987;110 ( Pt 5)():1309-22.
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1987: Palmer A M; Francis P T; Bowen D M; Benton J S; Neary D; Mann D M; Snowden J S
Catecholaminergic neurones assessed ante-mortem in Alzheimer's disease.
Brain research 1987;414(2):365-75.
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1987: Procter A W; Palmer A M; Bowen D M; Murphy E; Neary D
Glutamatergic denervation in Alzheimer's disease--a cautionary note.
Journal of neurology, neurosurgery, and psychiatry 1987;50(6):825.
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1987: Sims N R; Blass J P; Murphy C; Bowen D M; Neary D
Phosphofructokinase activity in the brain in Alzheimer's disease.
Annals of neurology 1987;21(5):509-10.
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1987: Francis P T; Bowen D M; Lowe S L; Neary D; Mann D M; Snowden J S
Somatostatin content and release measured in cerebral biopsies from demented patients.
Journal of the neurological sciences 1987;78(1):1-16.
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1987: Francis P T; Carl R; Pearson A; Lowe S L; Neal J W; Stephens P H; Powell T P; Bowen D M
The dementia of Alzheimer's disease: an update.
Journal of neurology, neurosurgery, and psychiatry 1987;50(2):242-3.
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1987: Palmer A M; Wilcock G K; Esiri M M; Francis P T; Bowen D M
Monoaminergic innervation of the frontal and temporal lobes in Alzheimer's disease.
Brain research 1987;401(2):231-8.
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1987: Palmer A M; Francis P T; Benton J S; Sims N R; Mann D M; Neary D; Snowden J S; Bowen D M
Presynaptic serotonergic dysfunction in patients with Alzheimer's disease.
Journal of neurochemistry 1987;48(1):8-15.
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1986: Procter A W; Palmer A M; Stratmann G C; Bowen D M
Glutamate/aspartate-releasing neurons in Alzheimer's disease.
The New England journal of medicine 1986;314(26):1711-2.
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1986: Palmer A M; Procter A W; Stratmann G C; Bowen D M
Excitatory amino acid-releasing and cholinergic neurones in Alzheimer's disease.
Neuroscience letters 1986;66(2):199-204.
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1986: Muller D P; Metcalfe T; Bowen D M
Vitamin E in brains of patients with Alzheimer's disease and Down's syndrome.
Lancet 1986;1(8489):1093-4.
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1986: Neary D; Snowden J S; Mann D M; Bowen D M; Sims N R; Northen B; Yates P O; Davison A N
Alzheimer's disease: a correlative study.
Journal of neurology, neurosurgery, and psychiatry 1986;49(3):229-37.
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1986: Middlemiss D N; Palmer A M; Edel N; Bowen D M
Binding of the novel serotonin agonist 8-hydroxy-2-(di-n-propylamino) tetralin in normal and Alzheimer brain.
Journal of neurochemistry 1986;46(3):993-6.
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1986: Neary D; Snowden J S; Bowen D M; Sims N R; Mann D M; Yates P O; Davison A N
Cerebral biopsy in the investigation of presenile dementia due to cerebral atrophy.
Journal of neurology, neurosurgery, and psychiatry 1986;49(2):157-62.
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1986: Neary D; Snowden J S; Bowen D M; Sims N R; Mann D M; Benton J S; Northen B; Yates P O; Davison A N
Neuropsychological syndromes in presenile dementia due to cerebral atrophy.
Journal of neurology, neurosurgery, and psychiatry 1986;49(2):163-74.
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1986: Bowen D M; Davison A N
Biochemical studies of nerve cells and energy metabolism in Alzheimer's disease.
British medical bulletin 1986;42(1):75-80.
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1986: Atterwill C K; Bowen D M
Neurotrophic factor for central cholinergic neurones is present in both normal and Alzheimer brain tissue.
Acta neuropathologica 1986;69(3-4):341-2.
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1985: Francis P T; Palmer A M; Sims N R; Bowen D M; Davison A N; Esiri M M; Neary D; Snowden J S; Wilcock G K
Neurochemical studies of early-onset Alzheimer's disease. Possible influence on treatment.
The New England journal of medicine 1985;313(1):7-11.
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1985: Smith C C; Bowen D M; Francis P T; Snowden J S; Neary D
Putative amino acid transmitters in lumbar cerebrospinal fluid of patients with histologically verified Alzheimer's dementia.
Journal of neurology, neurosurgery, and psychiatry 1985;48(5):469-71.
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1985: Bowen D M; Neary D
Cerebral biopsy in the study of Alzheimer's disease.
Bulletin of clinical neurosciences 1985;50():44-8.
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1984: Pearce B R; Bowen D M
[3H]Kainic acid binding and choline acetyltransferase activity in Alzheimer's dementia.
Brain research 1984;310(2):376-8.
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1984: Palmer A M; Sims N R; Bowen D M; Neary D; Palo J; Wikstrom J; Davison A N
Monoamine metabolite concentrations in lumbar cerebrospinal fluid of patients with histologically verified Alzheimer's dementia.
Journal of neurology, neurosurgery, and psychiatry 1984;47(5):481-4.
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1984: Bowen D M; Davison A N
Dementia in the elderly: biochemical aspects.
Journal of the Royal College of Physicians of London 1984;18(1):25-7.
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1984: Bowen D M
Cellular ageing: selective vulnerability of cholinergic neurones in human brain.
Monographs in developmental biology 1984;17():42-59.
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1984: Francis P T; Bowen D M; Neary D; Palo J; Wikstrom J; Olney J
Somatostatin-like immunoreactivity in lumbar cerebrospinal fluid from neurohistologically examined demented patients.
Neurobiology of aging 1984;5(3):183-6.
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1984: Pearce B R; Palmer A M; Bowen D M; Wilcock G K; Esiri M M; Davison A N
Neurotransmitter dysfunction and atrophy of the caudate nucleus in Alzheimer's disease.
Neurochemical pathology 1984;2(4):221-32.
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1983: Sims N R; Bowen D M; Neary D; Davison A N
Metabolic processes in Alzheimer's disease: adenine nucleotide content and production of 14CO2 from [U-14C]glucose in vitro in human neocortex.
Journal of neurochemistry 1983;41(5):1329-34.
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1983: Bowen D M; Allen S J; Benton J S; Goodhardt M J; Haan E A; Palmer A M; Sims N R; Smith C C; Spillane J A; Esiri M M; Neary D; Snowdon J S; Wilcock G K; Davison A N
Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease.
Journal of neurochemistry 1983;41(1):266-72.
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1983: Allen S J; Benton J S; Goodhardt M J; Haan E A; Sims N R; Smith C C; Spillane J A; Bowen D M; Davison A N
Biochemical evidence of selective nerve cell changes in the normal ageing human and rat brain.
Journal of neurochemistry 1983;41(1):256-65.
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1983: Smith C C; Bowen D M; Davison A N
The evoked release of endogenous amino acids from tissue prisms of human neocortex.
Brain research 1983;269(1):103-9.
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1983: Wilcock G K; Esiri M M; Bowen D M; Smith C C
The nucleus basalis in Alzheimer's disease: cell counts and cortical biochemistry.
Neuropathology and applied neurobiology 1983;9(3):175-9.
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1983: Smith C C; Bowen D M; Sims N R; Neary D; Davison A N
Amino acid release from biopsy samples of temporal neocortex from patients with Alzheimer's disease.
Brain research 1983;264(1):138-41.
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1983: Sims N R; Bowen D M; Allen S J; Smith C C; Neary D; Thomas D J; Davison A N
Presynaptic cholinergic dysfunction in patients with dementia.
Journal of neurochemistry 1983;40(2):503-9.
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1983: Bowen D M; Davison A N
The failing brain.
Journal of chronic diseases 1983;36(1):3-13.
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1982: Wilcock G K; Esiri M M; Bowen D M; Smith C C
Alzheimer's disease. Correlation of cortical choline acetyltransferase activity with the severity of dementia and histological abnormalities.
Journal of the neurological sciences 1982;57(2-3):407-17.
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1982: Bowen D M; Benton J S; Spillane J A; Smith C C; Allen S J
Choline acetyltransferase activity and histopathology of frontal neocortex from biopsies of demented patients.
Journal of the neurological sciences 1982;57(2-3):191-202.
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1982: Bowen D M; Sims N R; Lee K A; Marek K L
Acetylcholine synthesis and glucose oxidation are preserved in human brain obtained shortly after death.
Neuroscience letters 1982;31(2):195-9.
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1982: Marek K L; Bowen D M; Sims N R; Davison A N
Stimulation of acetylcholine synthesis by blockade of presynaptic muscarinic inhibitory autoreceptors: observations in rat and human brain preparations and comparison with the effect of choline.
Life sciences 1982;30(18):1517-24.
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1982: Bowen D M; Marek K L
Evidence for the pharmacological similarity between the central presynaptic muscarinic autoreceptor and postsynaptic muscarinic receptors.
British journal of pharmacology 1982;75(2):367-72.
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1982: Sims N R; Marek K L; Bowen D M; Davison A N
Production of [14C]acetylcholine and [14C]carbon dioxide from [U-14C]glucose in tissue prisms from aging rat brain.
Journal of neurochemistry 1982;38(2):488-92.
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1982: Benton J S; Bowen D M; Allen S J; Haan E A; Davison A N; Neary D; Murphy R P; Snowden J S
Alzheimer's disease as a disorder of isodendritic core.
Lancet 1982;1(8269):456.
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1982: Bowen D M; Sims N R; Davison A N
Neurochemistry of Alzheimer's disease: an update.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1982;Suppl 5():127-32.
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1981: Bowen D M; Sims N R; Benton J S; Curzon G; Davison A N; Neary D; Thomas D J
Treatment of Alzheimer's disease: a cautionary note.
The New England journal of medicine 1981;305(17):1016.
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1981: Haan E A; Bowen D M
Protection of neocortical tissue prisms from freeze-thaw injury by dimethyl sulphoxide.
Journal of neurochemistry 1981;37(1):243-6.
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1981: Sims N R; Bowen D M; Davison A N
[14C]acetylcholine synthesis and [14C]carbon dioxide production from [U-14C]glucose by tissue prisms from human neocortex.
The Biochemical journal 1981;196(3):867-76.
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1980: Bowen D M; Davison A N
Biochemical changes in the cholinergic system of the ageing brain and in senile dementia.
Psychological medicine 1980;10(2):315-9.
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1980: Sims N R; Bowen D M; Smith C C; Flack R H; Davison A N; Snowden J S; Neary D
Glucose metabolism and acetylcholine synthesis in relation to neuronal activity in Alzheimer's disease.
Lancet 1980;1(8164):333-6.
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1979: Bowen D M; White P; Spillane J A; Goodhardt M J; Curzon G; Iwangoff P; Meier-Ruge W; Davison A N
Accelerated ageing or selective neuronal loss as an important cause of dementia?
Lancet 1979;1(8106):11-4.
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1978: White P; Bowen D M; Davison A N
Alzheimer's disease: distribution of protein on sucrose density gradient centrifugation.
Acta neuropathologica 1978;41(3):253-6.
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1977: Spillane J A; Goodhart M J; White P; Bowen D M; Davison A N
Choline in Alzheimer's disease.
Lancet 1977;2(8042):826-7.
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1977: Bowen D M; Smith C B; White P; Flack R H; Carrasco L H; Gedye J L; Davison A N
Chemical pathology of this organic dementias. II. Quantitative estimation of cellular changes in post-mortem brains.
Brain : a journal of neurology 1977;100(3):427-53.
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1977: Bowen D M; Smith C B; White P; Goodhardt M J; Spillane J A; Flack R H; Davison A N
Chemical pathology of organic dementias. I. Validity of biochemical measurements on human post-mortem brain specimens.
Brain : a journal of neurology 1977;100(3):397-426.
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1977: Bowen D M
Biochemistry of Dementias.
Proceedings of the Royal Society of Medicine 1977;70(5):351-3.
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1977: Spillane J A; White P; Goodhardt W J; Flack R H; Bowen D M; Davison A N
Selective vulnerability of neurones in organic dementia.
Nature 1977;266(5602):558-9.
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1977: White P; Hiley C R; Goodhardt M J; Carrasco L H; Keet J P; Williams I E; Bowen D M
Neocortical cholinergic neurons in elderly people.
Lancet 1977;1(8013):668-71.
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1977: Goodhardt M J; Strong A J; Bowen D M; White P; Branston N M; Symon L; Davison A N
The effects of middle-cerebral-artery occlusion on neurotransmitter metabolism in baboons.
Biochemical Society transactions 1977;5(1):160-3.
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1977: Strong A J; Goodhardt M J; Branston N M; Bowen D M; Symon L
The relationship between intensity and duration of cortical ischaemia and reduction of synaptosomal uptake of neurotransmitter in baboons.
Acta neurologica Scandinavica. Supplementum 1977;64():372-3.
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1976: Smith C B; Bowen D M
Soluble proteins in normal and diseased human brain.
Journal of neurochemistry 1976;27(6):1521-8.
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1976: Bowen D M; Goodhardt M J; Strong A J; Smith C B; White P; Branston N M; Symon L; Davison A N
Biochemical indices of brain structure, function and "hypoxia" in cortex from baboons with middle cerebral artery occlusion.
Brain research 1976;117(3):503-7.
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1976: Bowen D M; Smith C B; White P; Davison A N
Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies.
Brain : a journal of neurology 1976;99(3):459-96.
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1975: Bowen D M; Davison A N
Letter: Extrapyramidal diseases and dementia.
Lancet 1975;1(7917):1199-200.
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1974: Bowen D M; Flack R H; Martin R O; Smith C B; White P; Davison A N
Biochemical studies on degenerative neurological disorders. I. Acute experimental encephalitis.
Journal of neurochemistry 1974;22(6):1099-107.
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1974: Bowen D M; White P; Flack R H; Smith C B; Davison A N
Brain-decarboxylase activities as indices of pathological change in senile dementia.
Lancet 1974;1(7869):1247-9.
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1974: Bowen D M; Davison A N
Carboxypeptidase of human brain: hydrolysis of benzyloxycarbonyl-glutamyl-Ltyrosine in normal and diseased tissue.
Journal of neurochemistry 1974;22(4):607-8.
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1974: Ramsey R B; Banik N L; Bowen D M; Scott T; Davison A N
Biochemical and ultrastructural studies on subacute sclerosing panencephalitis and demyelination.
Journal of the neurological sciences 1974;21(2):213-25.
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1973: Bowen D M; Smith C B; Davison A N
Molecular changes in senile dementia.
Brain : a journal of neurology 1973;96(4):849-56.
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1973: Bowen D M; Davison A N
Cathepsin A in human brain and spleen.
The Biochemical journal 1973;131(2):417-9.
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1969: Bowen D M; Radin N S
Cerebroside galactosidase: a method for determination and a comparison with other lysosomal enzymes in developing rat brain.
Journal of neurochemistry 1969;16(4):501-11.
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1969: Bowen D M; Radin N S
Hydrolase activities in brain of neurological mutants: cerebroside galactosidase, nitrophenyl galactoside hydrolase, nitrophenyl glucoside hydrolase and sulphatase.
Journal of neurochemistry 1969;16(3):457-60.
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1968: Bowen D M; Radin N S
Properties of cerebroside galactosidase.
Biochimica et biophysica acta 1968;152(3):599-610.
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1968: Bowen D M; Radin N S
Purification of cerebroside galactosidase from rat brain.
Biochimica et biophysica acta 1968;152(3):587-98.
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1968: Bowen D M; Radin N S
Hydroxy fatty acid metabolism in brain.
Advances in lipid research 1968;6():255-72.
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1966: Hajra A K; Bowen D M; Kishimoto Y; Radin N S
Cerebroside galactosidase of brain.
Journal of lipid research 1966;7(3):379-86.
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1964: BOWEN D M; OLSON R E
EFFECT OF NICOTINIC ACID ON STEROL BIOSYNTHESIS IN SACCHAROMYCES CEREVISIAE.
Nature 1964;203():762-3.
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