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Timothy Veenstra

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Proteomics

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Vyomesh Patel; James F Rusling; Bhuvanesh Singh; Uttam K Sinha; Timothy D Veenstra; Ruchika Malhotra; Christina A Marsh; Daniel Martin; Alfredo A Molinolo; Cherie-Ann Nathan; Colleen L Doçi; J Silvio Gutkind
DSG3 as a biomarker for the ultrasensitive detection of occult lymph node metastasis in oral cancer using nanostructured immunoarrays.
Barbara J Fuhrman; Larry K Keefer; Ruth M Pfeiffer; Timothy D Veenstra; Anna H Wu; Xia Xu; Regina G Ziegler
Green tea intake is associated with urinary estrogen profiles in Japanese-American women.
Cher M Dallal; Roni Falk; Trisha F Hue; James V Lacey; Andrea Lacroix; Ruth Pfeiffer; Michael Pollak; Jeffrey A Tice; Timothy D Veenstra; Xia Xu; Douglas C Bauer; Louise A Brinton; Diana S M Buist; Jane A Cauley; Victoria M Chia
Obesity-related hormones and endometrial cancer among postmenopausal women: a nested case-control study within the B~FIT cohort.

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2013: Vyomesh Patel; James F Rusling; Bhuvanesh Singh; Uttam K Sinha; Timothy D Veenstra; Ruchika Malhotra; Christina A Marsh; Daniel Martin; Alfredo A Molinolo; Cherie-Ann Nathan; Colleen L Doçi; J Silvio Gutkind
DSG3 as a biomarker for the ultrasensitive detection of occult lymph node metastasis in oral cancer using nanostructured immunoarrays.
Oral oncology 2013;49(2):93-101.
2013: Barbara J Fuhrman; Larry K Keefer; Ruth M Pfeiffer; Timothy D Veenstra; Anna H Wu; Xia Xu; Regina G Ziegler
Green tea intake is associated with urinary estrogen profiles in Japanese-American women.
Nutrition journal 2013;12():25.
2013: Cher M Dallal; Roni Falk; Trisha F Hue; James V Lacey; Andrea Lacroix; Ruth Pfeiffer; Michael Pollak; Jeffrey A Tice; Timothy D Veenstra; Xia Xu; Douglas C Bauer; Louise A Brinton; Diana S M Buist; Jane A Cauley; Victoria M Chia
Obesity-related hormones and endometrial cancer among postmenopausal women: a nested case-control study within the B~FIT cohort.
Endocrine-related cancer 2013;20(1):151-60.
2012: Leelamma M Panicker; Tea Soon Park; Brijesh Patel; Swamy Polumuri; Ellen Sidransky; Barbara K Stubblefield; Nahid Tayebi; Timothy D Veenstra; Stefanie N Vogel; ELIAS ZAMBIDIS; Ola Awad; Judi L Azevedo; Ehud Goldin; M Athar Masood; Diana Miller; Ricardo A Feldman
Induced pluripotent stem cell model recapitulates pathologic hallmarks of Gaucher disease.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(44):18054-9.
2012: Barbara J Fuhrman; Maddalena Barba; Louise A Brinton; Celia Byrne; Cher M Dallal; Paola C Muti; Ruth M Pfeiffer; Barbara E Teter; Timothy D Veenstra; Xia Xu; Gretchen L Gierach
Estrogen metabolism and mammographic density in postmenopausal women: a cross-sectional study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2012;21(9):1582-91.
2012: Guillaume P Leboucher; Kristin C Shaw; Yien Che Tsai; Timothy D Veenstra; Mei Yang; Ming Zhou; Michael H Glickman; Allan M Weissman
Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis.
Molecular cell 2012;47(4):547-57.
2012: Kyung Ho Lee; Jeong K Bang; Yuan Gao; Yoshikazu Johmura; Jung-Eun Park; Timothy D Veenstra; Bo Yeon Kim; Li-Rong Yu; Ming Zhou; Kyung S Lee
Identification of a novel Wnt5a-CK1ɛ-Dvl2-Plk1-mediated primary cilia disassembly pathway.
The EMBO journal 2012;31(14):3104-17.
2012: Zhen Xiao; Fung-Lung Chung; Lixin Mi; Timothy D Veenstra
Proteomic analysis of covalent modifications of tubulins by isothiocyanates.
The Journal of nutrition 2012;142(7):1377S-81S.
2012: Joseph W Briggs; Gulay Bulut; Jessica Cassavaugh; Kristi Chakrabarti; Qingrong Chen; Javed Khan; Rachel Nguyen; Said Rahim; Ling Ren; Aykut Uren; Timothy D Veenstra; Jun S Wei; Ming Zhou; Chand Khanna
The ezrin metastatic phenotype is associated with the initiation of protein translation.
Neoplasia (New York, N.Y.) 2012;14(4):297-310.
2012: Bih-Rong Wei; Xiaoying Ye; Jennifer E Dwyer; Shelley B Hoover; Donald J Johann; Mia Kumar; Brian Luke; DaRue A Prieto; Heather R Shive; R Mark Simpson; Timothy D Veenstra; Joshua D Webster; Josip Blonder
Proteomic profiling of H-Ras-G12V induced hypertrophic cardiomyopathy in transgenic mice using comparative LC-MS analysis of thin fresh-frozen tissue sections.
Journal of proteome research 2012;11(3):1561-70.
2012: Barbara J Fuhrman; Mitchell H Gail; Robert N Hoover; Claudine Isaacs; Larry K Keefer; Catherine Schairer; Laura Y Sue; Timothy D Veenstra; Xia Xu; Christine D Berg; Jennifer Boyd-Morin; Saundra S Buys; Regina G Ziegler
Estrogen metabolism and risk of breast cancer in postmenopausal women.
Journal of the National Cancer Institute 2012;104(4):326-39.
2012: M Athar Masood; Raghavendra P Rao; Jairaj K Acharya; Josip Blonder; Timothy D Veenstra
Quantitation of multiple sphingolipid classes using normal and reversed-phase LC-ESI-MS/MS: comparative profiling of two cell lines.
Lipids 2012;47(2):209-26.
2012: Roberto Flores; Barbara Fuhrman; Mitchell H Gail; Pawel Gajer; Jacques Ravel; Jianxin Shi; Timothy D Veenstra; Xia Xu; James J Goedert
Fecal microbial determinants of fecal and systemic estrogens and estrogen metabolites: a cross-sectional study.
Journal of translational medicine 2012;10():253.
2012: Xiaoying Ye; King C Chan; Donald J Johann; Brian T Luke; Akira Ono; DaRue A Prieto; Timothy D Veenstra; Josip Blonder
Post-digestion ¹⁸O exchange/labeling for quantitative shotgun proteomics of membrane proteins.
Methods in molecular biology (Clifton, N.J.) 2012;893():223-40.
2012: Xia Xu; Timothy D Veenstra
Concentration of endogenous estrogens and estrogen metabolites in the NCI-60 human tumor cell lines.
Genome medicine 2012;4(4):31.
2012: Timothy D Veenstra
Metabolomics: the final frontier?
Genome medicine 2012;4(4):40.
2011: Timothy D Veenstra
Where are all the biomarkers?
Expert review of proteomics 2011;8(6):681-3.
2011: Lixin Mi; Nicolas A Stewart; Timothy D Veenstra; Xiantao Wang; Zhen Xiao; Thomas P Conrads; Sudha Govind; Brian L Hood; Fung-Lung Chung
Identification of potential protein targets of isothiocyanates by proteomics.
Chemical research in toxicology 2011;24(10):1735-43.
2011: Yoshikazu Johmura; Bo-Yeon Kim; Jeong K Bang; Raymond L. Erikson; Jung-Eun Park; Nak-Kyun Soung; Timothy D Veenstra; Li-Rong Yu; Ming Zhou; Kyung S Lee
Regulation of microtubule-based microtubule nucleation by mammalian polo-like kinase 1.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(28):11446-51.
2011: Lixin Mi; Zhen Xiao; Timothy D Veenstra; Fung-Lung Chung
Proteomic identification of binding targets of isothiocyanates: A perspective on techniques.
Journal of proteomics 2011;74(7):1036-44.
2011: Josip Blonder; Haleem J Issaq; Timothy D Veenstra
Proteomic biomarker discovery: it's more than just mass spectrometry.
Electrophoresis 2011;32(13):1541-8.
2011: Stephen D Fox; Roni T Falk; Timothy D Veenstra; Haleem J Issaq
Quantitation of free and total bisphenol A in human urine using liquid chromatography-tandem mass spectrometry.
Journal of separation science 2011;34(11):1268-74.
2011: JM Jones; Anamika Bhattacharyya; Carrie Simkus; Brice Vallieres; Timothy D Veenstra; Ming Zhou
The RAG1 V(D)J recombinase/ubiquitin ligase promotes ubiquitylation of acetylated, phosphorylated histone 3.3.
Immunology letters 2011;136(2):156-62.
2011: Qiou Wei; Hong Jiang; Zhen Xiao; Alyson Baker; Matthew R Young; Timothy D Veenstra; Nancy H Colburn
Sulfiredoxin-Peroxiredoxin IV axis promotes human lung cancer progression through modulation of specific phosphokinase signaling.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(17):7004-9.
2011: Xing Zhang; Terrence W Brann; Ming Zhou; Jun Yang; Raphael M Oguariri; Kristy B Lidie; Hiromi Imamichi; Da-Wei Huang; Richard A Lempicki; Michael Baseler; Timothy D Veenstra; Howard A Young; H Clifford Lane; Tomozumi Imamichi
Cutting edge: Ku70 is a novel cytosolic DNA sensor that induces type III rather than type I IFN.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(8):4541-5.
2011: Timothy D Veenstra
Proteomics research in breast cancer: balancing discovery and hypothesis-driven studies.
Expert review of proteomics 2011;8(2):139-41.
2011: Haleem J Issaq; Timothy J Waybright; Timothy D Veenstra
Cancer biomarker discovery: Opportunities and pitfalls in analytical methods.
Electrophoresis 2011;32(9):967-75.
2011: Ourania Kosti; Xia Xu; Timothy D Veenstra; Ann W Hsing; Lisa W Chu; Lenka Goldman; Ionut Bebu; Sean Collins; Anatoly Dritschilo; John H Lynch; Radoslav Goldman
Urinary estrogen metabolites and prostate cancer risk: a pilot study.
The Prostate 2011;71(5):507-16.
2011: King C Chan; Timothy D Veenstra; Haleem J Issaq
Comparison of fluorescence, laser-induced fluorescence, and ultraviolet absorbance detection for measuring HPLC fractionated protein/peptide mixtures.
Analytical chemistry 2011;83(6):2394-6.
2011: Qing-Rong Chen; Li-Rong Yu; Patricia Tsang; Jun S Wei; Young K Song; Adam Cheuk; Joon-Yong Chung; Stephen M Hewitt; Timothy D Veenstra; Javed Khan
Systematic proteome analysis identifies transcription factor YY1 as a direct target of miR-34a.
Journal of proteome research 2011;10(2):479-87.
2011: Que N Van; Timothy D Veenstra; Haleem J Issaq
Metabolic profiling for the detection of bladder cancer.
Current urology reports 2011;12(1):34-40.
2011: Vijay V Upreti; Kwan-Hoon Moon; Li-Rong Yu; Insong J Lee; Natalie D. Eddington; Xiaoying Ye; Timothy D Veenstra; Byoung J Song
Increased oxidative-modifications of cytosolic proteins in 3,4-methylenedioxymethamphetamine (MDMA, ecstasy)-exposed rat liver.
Proteomics 2011;11(2):202-11.
2011: King C Chan; Timothy D Veenstra; Haleem J Issaq
Quantitation of nanoparticles in serum matrix by capillary electrophoresis.
Methods in molecular biology (Clifton, N.J.) 2011;697():145-53.
2010: Sudipto Das; Allen D Bosley; Xiaoying Ye; King C Chan; Isabel Chu; Jeffery E Green; Haleem J Issaq; Timothy D Veenstra; Thorkell Andresson
Comparison of strong cation exchange and SDS-PAGE fractionation for analysis of multiprotein complexes.
Journal of proteome research 2010;9(12):6696-704.
2010: Barbara J Fuhrman; Xia Xu; Roni T Falk; Susan E Hankinson; Timothy D Veenstra; Larry K Keefer; Regina G Ziegler
Stability of 15 estrogens and estrogen metabolites in urine samples under processing and storage conditions typically used in epidemiologic studies.
The International journal of biological markers 2010;25(4):185-94.
2010: J Wang; Tapasree Roy Sarkar; Ming Zhou; Shyam K Sharan; Daniel A Ritt; Timothy D Veenstra; Deborah K Morrison; A-Mei Huang; Esta Sterneck
CCAAT/enhancer binding protein delta (C/EBPdelta, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(37):16131-6.
2010: Regina G Ziegler; Jessica M Faupel-Badger; L Y Sue; B J Fuhrman; Roni T Falk; J Boyd-Morin; M K Henderson; Robert N Hoover; Timothy D Veenstra; Larry K Keefer; Xia Xu
A new approach to measuring estrogen exposure and metabolism in epidemiologic studies.
The Journal of steroid biochemistry and molecular biology 2010;121(3-5):538-45.
2010: Junghwa Lim; Ming Zhou; Timothy D Veenstra; Deborah K Morrison
The CNK1 scaffold binds cytohesins and promotes insulin pathway signaling.
Genes & development 2010;24(14):1496-506.
2010: Xiaoying Ye; Brian T Luke; Donald J Johann; Akira Ono; DaRue A Prieto; King C Chan; Haleem J Issaq; Timothy D Veenstra; Josip Blonder
Optimized method for computing (18)O/(16)O ratios of differentially stable-isotope labeled peptides in the context of postdigestion (18)O exchange/labeling.
Analytical chemistry 2010;82(13):5878-86.
2010: Sook Lee; Jon Shuman; Tad Guszczynski; Krisada Sakchaisri; Thomas Sebastian; Terry D Copeland; Maria Miller; Michael S Cohen; Jack Taunton; Robert C Smart; Zhen Xiao; Li-Rong Yu; Timothy D Veenstra; Peter F Johnson
RSK-mediated phosphorylation in the C/EBP{beta} leucine zipper regulates DNA binding, dimerization, and growth arrest activity.
Molecular and cellular biology 2010;30(11):2621-35.
2010: M Athar Masood; Changqing Yuan; Jairaj K Acharya; Timothy D Veenstra; Josip Blonder
Quantitation of ceramide phosphorylethanolamines containing saturated and unsaturated sphingoid base cores.
Analytical biochemistry 2010;400(2):259-69.
2010: Saravana P Selvanathan; Anjan G Thakurta; Jothy Dhakshnamoorthy; Ming Zhou; Timothy D Veenstra; Ravi Dhar
Schizosaccharomyces pombe Dss1p is a DNA damage checkpoint protein that recruits Rad24p, Cdc25p, and Rae1p to DNA double-strand breaks.
The Journal of biological chemistry 2010;285(19):14122-33.
2010: Timothy Waybright; Anthony M Avellino; Richard G Ellenbogen; Bradley J Hollinger; Timothy D Veenstra; Richard S Morrison
Characterization of the human ventricular cerebrospinal fluid proteome obtained from hydrocephalic patients.
Journal of proteomics 2010;73(6):1156-62.
2010: Elaine M Hurt; King Chan; Maria Ana Duhagon Serrat; Suneetha B Thomas; Timothy D Veenstra; William L Farrar
Identification of vitronectin as an extrinsic inducer of cancer stem cell differentiation and tumor formation.
Stem cells (Dayton, Ohio) 2010;28(3):390-8.
2010: Jodie M Fleming; Tyler C Miller; Mariam Quinones; Zhen Xiao; Xia Xu; Matthew J Meyer; Erika Ginsburg; Timothy D Veenstra; Barbara K Vonderhaar
The normal breast microenvironment of premenopausal women differentially influences the behavior of breast cancer cells in vitro and in vivo.
BMC medicine 2010;8():27.
2010: Jessica M Faupel-Badger; Barbara J Fuhrman; Xia Xu; Roni T Falk; Larry K Keefer; Timothy D Veenstra; Robert N Hoover; Regina G Ziegler
Comparison of liquid chromatography-tandem mass spectrometry, RIA, and ELISA methods for measurement of urinary estrogens.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010;19(1):292-300.
2010: Qing-Rong Chen; Young K Song; Li-Rong Yu; Jun S Wei; Joon-Yong Chung; Stephen M Hewitt; Timothy D Veenstra; Javed Khan
Global genomic and proteomic analysis identifies biological pathways related to high-risk neuroblastoma.
Journal of proteome research 2010;9(1):373-82.
2009: Xiaoying Ye; Donald J Johann; Ramin M Hakami; Zhen Xiao; Zhaojing Meng; Robert G Ulrich; Haleem J Issaq; Timothy D Veenstra; Josip Blonder
Optimization of protein solubilization for the analysis of the CD14 human monocyte membrane proteome using LC-MS/MS.
Journal of proteomics 2009;73(1):112-22.
2009: Barbara J Fuhrman; Ruth Pfeiffer; Xia Xu; Anna H Wu; Larissa Korde; Mitchell H Gail; Larry K Keefer; Timothy D Veenstra; Robert N Hoover; Regina G Ziegler
Soy intake is associated with increased 2-hydroxylation and decreased 16alpha-hydroxylation of estrogens in Asian-American women.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(10):2751-60.
2009: Carrie Simkus; Anamika Bhattacharyya; Ming Zhou; Timothy D Veenstra; JM Jones
Correlation between recombinase activating gene 1 ubiquitin ligase activity and V(D)J recombination.
Immunology 2009;128(2):206-17.
2009: Martin Zofall; Tamás Fischer; Ke Zhang; Ming Zhou; Bowen Cui; Timothy D Veenstra; Shiv I S Grewal
Histone H2A.Z cooperates with RNAi and heterochromatin factors to suppress antisense RNAs.
Nature 2009;461(7262):419-22.
2009: Malena B Rone; Jun Liu; Josip Blonder; Xiaoying Ye; Timothy D Veenstra; Jason C Young; Vassilios Papadopoulos
Targeting and insertion of the cholesterol-binding translocator protein into the outer mitochondrial membrane.
Biochemistry 2009;48(29):6909-20.
2009: Caroline Millet; Motozo Yamashita; Mary Heller; Li-Rong Yu; Timothy D Veenstra; Ying E Zhang
A negative feedback control of transforming growth factor-beta signaling by glycogen synthase kinase 3-mediated Smad3 linker phosphorylation at Ser-204.
The Journal of biological chemistry 2009;284(30):19808-16.
2009: Haleem J Issaq; Que N Van; Timothy J Waybright; GM Muschik; Timothy D Veenstra
Analytical and statistical approaches to metabolomics research.
Journal of separation science 2009;32(13):2183-99.
2009: Michele K Dougherty; Daniel A Ritt; Ming Zhou; Suzanne I Specht; Daniel M Monson; Timothy D Veenstra; Deborah K Morrison
KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals.
Molecular cell 2009;34(6):652-62.
2009: Tamás Fischer; Bowen Cui; Jothy Dhakshnamoorthy; Ming Zhou; Chanan Rubin; Martin Zofall; Timothy D Veenstra; Shiv I S Grewal
Diverse roles of HP1 proteins in heterochromatin assembly and functions in fission yeast.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(22):8998-9003.
2009: Timothy J Waybright; Timothy D Veenstra
Bringing protein biomarker discovery to the clinic.
Expert review of molecular diagnostics 2009;9(4):305-7.
2009: Daniel W Farlow; Xia Xu; Timothy D Veenstra
Quantitative measurement of endogenous estrogen metabolites, risk-factors for development of breast cancer, in commercial milk products by LC-MS/MS.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(13):1327-34.
2009: Kexin Xu; Hermela Shimelis; Douglas E Linn; Richeng Jiang; Xi Yang; Feng Sun; Zhiyong Guo; Hegang Chen; Wei Li; He-Ge Chen; Xiangtian Kong; Jonathan Melamed; Shengyun Fang; Zhen Xiao; Timothy D Veenstra; Yun Qiu
Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination.
Cancer cell 2009;15(4):270-82.
2009: Nak-Kyun Soung; Jung-Eun Park; Li-Rong Yu; Kyung H Lee; Jung-Min Lee; Jeong K Bang; Timothy D Veenstra; Kunsoo Rhee; Kyung S Lee
Plk1-dependent and -independent roles of an ODF2 splice variant, hCenexin1, at the centrosome of somatic cells.
Developmental cell 2009;16(4):539-50.
2009: Haleem J Issaq; King C Chan; Josip Blonder; Xiaoying Ye; Timothy D Veenstra
Separation, detection and quantitation of peptides by liquid chromatography and capillary electrochromatography.
Journal of chromatography. A 2009;1216(10):1825-37.
2009: Takuma Uo; Timothy D Veenstra; Richard S Morrison
Histone deacetylase inhibitors prevent p53-dependent and p53-independent Bax-mediated neuronal apoptosis through two distinct mechanisms.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(9):2824-32.
2009: Josip Blonder; Timothy D Veenstra
Clinical proteomic applications of formalin-fixed paraffin-embedded tissues.
Clinics in laboratory medicine 2009;29(1):101-13.
2009: Xiaoying Ye; Josip Blonder; Timothy D Veenstra
Targeted proteomics for validation of biomarkers in clinical samples.
Briefings in functional genomics & proteomics 2009;8(2):126-35.
2009: Zhen Xiao; Josip Blonder; Ming Zhou; Timothy D Veenstra
Proteomic analysis of extracellular matrix and vesicles.
Journal of proteomics 2009;72(1):34-45.
2009: Timothy D Veenstra
Using a global proteomic approach to identify proteins affected by estrogen therapy.
Genome medicine 2009;1(6):58.
2009: Que N Van; Timothy D Veenstra
How close is the bench to the bedside? Metabolic profiling in cancer research.
Genome medicine 2009;1(1):5.
2009: M Athar Masood; Xia Xu; Jairaj K Acharya; Timothy D Veenstra; Josip Blonder
Enhanced detection of sphingoid bases via divalent ruthenium bipyridine complex derivatization and electrospray ionization tandem mass spectrometry.
Analytical chemistry 2009;81(1):495-502.
2008: Xia Xu; Timothy D Veenstra
Analysis of biofluids for biomarker research.
Proteomics. Clinical applications 2008;2(10-11):1403-12.
2008: Lixin Mi; Zhen Xiao; Brian L Hood; Sivanesan Dakshanamurthy; Xiantao Wang; Sudha Govind; Thomas P Conrads; Timothy D Veenstra; Fung-Lung Chung
Covalent binding to tubulin by isothiocyanates. A mechanism of cell growth arrest and apoptosis.
The Journal of biological chemistry 2008;283(32):22136-46.
2008: Xia Xu; Essam El-Dine R Othman; Haleem J Issaq; Daniela Hornung; Ayman Al-Hendy; Timothy D Veenstra
Multiplexed quantitation of endogenous estrogens and estrogen metabolites in human peritoneal fluid.
Electrophoresis 2008;29(12):2706-13.
2008: Haleem J Issaq; Ofer Nativ; Timothy Waybright; Brian Luke; Timothy D Veenstra; Elias J Issaq; Alexander Kravstov; Michael Mullerad
Detection of bladder cancer in human urine by metabolomic profiling using high performance liquid chromatography/mass spectrometry.
The Journal of urology 2008;179(6):2422-6.
2008: Haleem J Issaq; Eric Abbott; Timothy D Veenstra
Utility of separation science in metabolomic studies.
Journal of separation science 2008;31(11):1936-47.
2008: Eric Abbott; Timothy D Veenstra; Haleem J Issaq
Clinical and pharmaceutical applications of packed-column supercritical fluid chromatography.
Journal of separation science 2008;31(8):1223-30.
2008: Ling-Hua Meng; Zhaojing Meng; Ze-Hong Miao; Timothy D Veenstra; Yves Pommier
Cytokeratin-RNA cross-linking mediated by the antitumor aminoflavone, 5-amino-2,3-fluorophenyl-6,8-difluoro-7-methyl-4H-1-benzopyran-4-one.
The Journal of pharmacology and experimental therapeutics 2008;325(2):674-80.
2008: Timothy D Veenstra; Katrin Marcus
Multidimensional advancement of neuroproteomics.
Expert review of proteomics 2008;5(2):149-51.
2008: DaRue A Prieto; Xiaoying Ye; Timothy D Veenstra
Proteomic analysis of traumatic brain injury: the search for biomarkers.
Expert review of proteomics 2008;5(2):283-91.
2008: Chong J Park; Jung-Eun Park; Tatiana S Karpova; Nak-Kyun Soung; Li-Rong Yu; Sukgil Song; Kyung H Lee; Xue Xia; Eugene Kang; Ilknur Dabanoglu; Doo-Yi Oh; James Y Zhang; Young H Kang; Stephen Wincovitch; Tim C Huffaker; Timothy D Veenstra; James G McNally; Kyung S Lee
Requirement for the budding yeast polo kinase Cdc5 in proper microtubule growth and dynamics.
Eukaryotic cell 2008;7(3):444-53.
2008: Vyomesh Patel; Brian L Hood; Alfredo A Molinolo; Norman H Lee; Thomas P Conrads; John C Braisted; David B Krizman; Timothy D Veenstra; J Silvio Gutkind
Proteomic analysis of laser-captured paraffin-embedded tissues: a molecular portrait of head and neck cancer progression.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(4):1002-14.
2008: Jong Heun Lee; Christine E Horak; Chand Khanna; Zhaojing Meng; Li-Rong Yu; Timothy D Veenstra; Patricia S Steeg
Alterations in Gemin5 expression contribute to alternative mRNA splicing patterns and tumor cell motility.
Cancer research 2008;68(3):639-44.
2008: Carol B Fowler; Robert E Cunningham; Timothy J Waybright; Josip Blonder; Timothy D Veenstra; timothy o'leary; Jeffrey T Mason
Elevated hydrostatic pressure promotes protein recovery from formalin-fixed, paraffin-embedded tissue surrogates.
Laboratory investigation; a journal of technical methods and pathology 2008;88(2):185-95.
2008: Que N Van; Haleem J Issaq; Qiujie Jiang; Qiaoli Li; Gary M Muschik; Timothy J Waybright; Hong Lou; Michael Dean; Jouni Uitto; Timothy D Veenstra
Comparison of 1D and 2D NMR spectroscopy for metabolic profiling.
Journal of proteome research 2008;7(2):630-9.
2008: Nicolas A Stewart; Timothy D Veenstra
Sample preparation for mass spectrometry analysis of formalin-fixed paraffin-embedded tissue: proteomic analysis of formalin-fixed tissue.
Methods in molecular biology (Clifton, N.J.) 2008;425():131-8.
2007: Yien Che Tsai; Arnulfo Mendoza; Jennifer Mariano; Ming Zhou; Zlatka Kostova; Bo Chen; Timothy D Veenstra; Stephen M Hewitt; Lee Helman; Chand Khanna; Allan M Weissman
The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation.
Nature medicine 2007;13(12):1504-9.
2007: JK McBee; Li-Rong Yu; Yoshito Kinoshita; Takuma Uo; Richard P Beyer; Timothy D Veenstra; Richard S Morrison
Proteomic analysis of protein expression changes in a model of gliomagenesis.
Proteomics. Clinical applications 2007;1(11):1485-98.
2007: Li-Rong Yu; Zhongyu Zhu; King C Chan; Haleem J Issaq; Dimiter S Dimitrov; Timothy D Veenstra
Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.
Journal of proteome research 2007;6(11):4150-62.
2007: Ming Zhou; Zhaojing Meng; Andrew G Jobson; Yves Pommier; Timothy D Veenstra
Detection of in vitro kinase generated protein phosphorylation sites using gamma[18O4]-ATP and mass spectrometry.
Analytical chemistry 2007;79(20):7603-10.
2007: Xia Xu; John M Roman; Haleem J Issaq; Larry K Keefer; Timothy D Veenstra; Regina G Ziegler
Quantitative measurement of endogenous estrogens and estrogen metabolites in human serum by liquid chromatography-tandem mass spectrometry.
Analytical chemistry 2007;79(20):7813-21.
2007: Li-Rong Yu; Haleem J Issaq; Timothy D Veenstra
Phosphoproteomics for the discovery of kinases as cancer biomarkers and drug targets.
Proteomics. Clinical applications 2007;1(9):1042-57.
2007: Li-Rong Yu; Timothy D Veenstra
AACR-FDA-NCI cancer biomarkers collaborative.
Expert review of molecular diagnostics 2007;7(5):507-9.
2007: Zhaojing Meng; Timothy D Veenstra
Proteomic analysis of serum, plasma, and lymph for the identification of biomarkers.
Proteomics. Clinical applications 2007;1(8):747-57.
2007: Ming Zhou; Timothy D Veenstra
Proteomic analysis of protein complexes.
Proteomics 2007;7(16):2688-97.
2007: Haleem J Issaq; Zhen Xiao; Timothy D Veenstra
Serum and plasma proteomics.
Chemical reviews 2007;107(8):3601-20.
2007: Lixin Mi; Xiantao Wang; Sudha Govind; Brian L Hood; Timothy D Veenstra; Thomas P Conrads; Daniel T Saha; Radoslav Goldman; Fung-Lung Chung
The role of protein binding in induction of apoptosis by phenethyl isothiocyanate and sulforaphane in human non-small lung cancer cells.
Cancer research 2007;67(13):6409-16.
2007: Nehal J Lakhani; Alex Sparreboom; Xia Xu; Timothy D Veenstra; Jürgen Venitz; William L Dahut; William D Figg
Characterization of in vitro and in vivo metabolic pathways of the investigational anticancer agent, 2-methoxyestradiol.
Journal of pharmaceutical sciences 2007;96(7):1821-31.
2007: Josip Blonder; Timothy D Veenstra
Computational prediction of proteotypic peptides.
Expert review of proteomics 2007;4(3):351-4.
2007: Haleem J Issaq; Timothy D Veenstra
The role of electrophoresis in disease biomarker discovery.
Electrophoresis 2007;28(12):1980-8.
2007: Li-Rong Yu; King C Chan; Hidetoshi Tahara; David A Lucas; Koushik Chatterjee; Haleem J Issaq; Timothy D Veenstra
Quantitative proteomic analysis of human breast epithelial cells with differential telomere length.
Biochemical and biophysical research communications 2007;356(4):942-7.
2007: King C Chan; Anil K Patri; Timothy D Veenstra; Scott E McNeil; Haleem J Issaq
Analysis of fullerene-based nanomaterial in serum matrix by CE.
Electrophoresis 2007;28(10):1518-24.
2007: Courtney A Granville; Noel A Warfel; Junji Tsurutani; M Christine Hollander; Matthew Robertson; Stephen D Fox; Timothy D Veenstra; Haleem J Issaq; R Ilona Linnoila; Phillip A Dennis
Identification of a highly effective rapamycin schedule that markedly reduces the size, multiplicity, and phenotypic progression of tobacco carcinogen-induced murine lung tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(7):2281-9.
2007: Timothy D Veenstra
Global and targeted quantitative proteomics for biomarker discovery.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;847(1):3-11.
2007: Zhen Xiao; Corinne E Camalier; Kunio Nagashima; King C Chan; David A Lucas; M Jason de la Cruz; Michelle Gignac; Stephen Lockett; Haleem J Issaq; Timothy D Veenstra; Thomas P Conrads; George R Beck
Analysis of the extracellular matrix vesicle proteome in mineralizing osteoblasts.
Journal of cellular physiology 2007;210(2):325-35.
2007: Daniel A Ritt; Ming Zhou; Thomas P Conrads; Timothy D Veenstra; Terry D Copeland; Deborah K Morrison
CK2 Is a component of the KSR1 scaffold complex that contributes to Raf kinase activation.
Current biology : CB 2007;17(2):179-84.
2007: Cai Bowen; August Stuart; Jeong-Ho Ju; Jenny Tuan; Josip Blonder; Thomas P Conrads; Timothy D Veenstra; Edward P Gelmann
NKX3.1 homeodomain protein binds to topoisomerase I and enhances its activity.
Cancer research 2007;67(2):455-64.
2007: Xia Xu; Larry K Keefer; Regina G Ziegler; Timothy D Veenstra
A liquid chromatography-mass spectrometry method for the quantitative analysis of urinary endogenous estrogen metabolites.
Nature protocols 2007;2(6):1350-5.
2006: Thomas P Conrads; Gillian Tocci; Brian L Hood; Chen-Ou Zhang; Li Guo; Kristopher R Koch; Christopher J Michejda; Timothy D Veenstra; Susan K Keay
CKAP4/p63 is a receptor for the frizzled-8 protein-related antiproliferative factor from interstitial cystitis patients.
The Journal of biological chemistry 2006;281(49):37836-43.
2006: Ming Zhou; Timothy D Veenstra
Multiplexed immunofluorescence microscopy for the interrogation of cellular protein complexes.
Expert review of proteomics 2006;3(6):581-3.
2006: Young H Kang; Jung-Eun Park; Li-Rong Yu; Nak-Kyun Soung; Sang-Moon Yun; Jeong K Bang; Yeon-Sun Seong; Hongtao Yu; Susan H Garfield; Timothy D Veenstra; Kyung S Lee
Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation.
Molecular cell 2006;24(3):409-22.
2006: Luke H Stockwin; Josip Blonder; Maja A Bumke; David A Lucas; King C Chan; Thomas P Conrads; Haleem J Issaq; Timothy D Veenstra; Dianne L Newton; Susanna M Rybak
Proteomic analysis of plasma membrane from hypoxia-adapted malignant melanoma.
Journal of proteome research 2006;5(11):2996-3007.
2006: Josip Blonder; Zhen Xiao; Timothy D Veenstra
Proteomic profiling of differentiating osteoblasts.
Expert review of proteomics 2006;3(5):483-96.
2006: Zhiyong Guo; Bojie Dai; Tianyun Jiang; Kexin Xu; Yingqiu Xie; Oekyung Kim; Issa Nesheiwat; Xiangtian Kong; Jonathan Melamed; Venkatesh D Handratta; Vincent Njar; Angela Brodie; Li-Rong Yu; Timothy D Veenstra; Hegang Chen; Yun Qiu
Regulation of androgen receptor activity by tyrosine phosphorylation.
Cancer cell 2006;10(4):309-19.
2006: Jens K Habermann; Uwe J Roblick; Brian T Luke; DaRue A Prieto; William J J Finlay; Vladimir N Podust; John M Roman; Elisabeth Oevermann; T H K Schiedeck; Nils Homann; Michael Duchrow; Thomas P Conrads; Timothy D Veenstra; Stanley K Burt; Hans-Peter Bruch; Gert Auer; Thomas Ried
Increased serum levels of complement C3a anaphylatoxin indicate the presence of colorectal tumors.
Gastroenterology 2006;131(4):1020-9; quiz 1284.
2006: Satoshi Asano; Jung-Eun Park; Li-Rong Yu; Ming Zhou; Krisada Sakchaisri; Chong J Park; Young H Kang; Jeremy Thorner; Timothy D Veenstra; Kyung S Lee
Direct phosphorylation and activation of a Nim1-related kinase Gin4 by Elm1 in budding yeast.
The Journal of biological chemistry 2006;281(37):27090-8.
2006: Ming Zhou; DaRue A Prieto; David A Lucas; King C Chan; Haleem J Issaq; Timothy D Veenstra; Thomas P Conrads
Identification of the SELDI ProteinChip human serum retentate by microcapillary liquid chromatography-tandem mass spectrometry.
Journal of proteome research 2006;5(9):2207-16.
2006: Elena Chertova; Oleg Chertov; Lori V Coren; James D Roser; Charles M Trubey; Julian W Bess; Raymond C Sowder; Eugene V Barsov; Brian L Hood; Robert J Fisher; Kunio Nagashima; Thomas P Conrads; Timothy D Veenstra; Jeffrey D Lifson; David E Ott
Proteomic and biochemical analysis of purified human immunodeficiency virus type 1 produced from infected monocyte-derived macrophages.
Journal of virology 2006;80(18):9039-52.
2006: Siun Murphy; Bruno Larrivée; Ingrid Pollet; Kyle S Craig; David E Williams; Xin-Hui Huang; Megan Abbott; Fred Wong; Cameron Curtis; Thomas P Conrads; Timothy D Veenstra; Mira Puri; York Hsiang; Michel Roberge; Raymond J Andersen; Aly Karsan
Identification of sokotrasterol sulfate as a novel proangiogenic steroid.
Circulation research 2006;99(3):257-65.
2006: Zhaojing Meng; Corinne E Camalier; David A Lucas; Timothy D Veenstra; George R Beck; Thomas P Conrads
Probing early growth response 1 interacting proteins at the active promoter in osteoblast cells using oligoprecipitation and mass spectrometry.
Journal of proteome research 2006;5(8):1931-9.
2006: Haiyan Yang; Li-Rong Yu; Ming Yi; David A Lucas; Luanne Lukes; Mindy Lancaster; King C Chan; Haleem J Issaq; Robert M Stephens; Thomas P Conrads; Timothy D Veenstra; Kent W Hunter
Parallel analysis of transcript and translation profiles: identification of metastasis-related signal pathways differentially regulated by drug and genetic modifications.
Journal of proteome research 2006;5(7):1555-67.
2006: Brian L Hood; Thomas P Conrads; Timothy D Veenstra
Mass spectrometric analysis of formalin-fixed paraffin-embedded tissue: unlocking the proteome within.
Proteomics 2006;6(14):4106-14.
2006: Brian L Hood; Thomas P Conrads; Timothy D Veenstra
Unravelling the proteome of formalin-fixed paraffin-embedded tissue.
Briefings in functional genomics & proteomics 2006;5(2):169-75.
2006: Iqbal Unnisa Ali; Zhen Xiao; Winfred F Malone; Mylinh Smith; Thomas P Conrads; Timothy D Veenstra; Peter Greenwald; Brian T Luke; Jerry W McLarty
Plasma proteomic profiling: search for lung cancer diagnostic and early detection markers.
Oncology reports 2006;15(5):1367-72.
2006: Xia Xu; John M Roman; Timothy D Veenstra; Jennifer Van Anda; Regina G Ziegler; Haleem J Issaq
Analysis of fifteen estrogen metabolites using packed column supercritical fluid chromatography-mass spectrometry.
Analytical chemistry 2006;78(5):1553-8.
2006: Li Kong; Joseph E Saavedra; Gregory S Buzard; Xia Xu; Brian L Hood; Thomas P Conrads; Timothy D Veenstra; Larry K Keefer
Deamidation of peptides in aerobic nitric oxide solution by a nitrosative pathway.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2006;14(2):144-51.
2006: Josip Blonder; Li-Rong Yu; Galina Radeva; King C Chan; David A Lucas; Timothy J Waybright; Haleem J Issaq; Frances Sharom; Timothy D Veenstra
Combined chemical and enzymatic stable isotope labeling for quantitative profiling of detergent-insoluble membrane proteins isolated using Triton X-100 and Brij-96.
Journal of proteome research 2006;5(2):349-60.
2006: T Hara; M Abe; Hiroki Inoue; Li-Rong Yu; Timothy D Veenstra; Young H Kang; Kyung S Lee; Toru Miki
Cytokinesis regulator ECT2 changes its conformation through phosphorylation at Thr-341 in G2/M phase.
Oncogene 2006;25(4):566-78.
2006: Josip Blonder; King C Chan; Haleem J Issaq; Timothy D Veenstra
Identification of membrane proteins from mammalian cell/tissue using methanol-facilitated solubilization and tryptic digestion coupled with 2D-LC-MS/MS.
Nature protocols 2006;1(6):2784-90.
2005: Brian L Hood; Marlene M Darfler; Thomas G Guiel; Bungo Furusato; David A Lucas; Bradley R Ringeisen; Isabell A Sesterhenn; Thomas P Conrads; Timothy D Veenstra; David B Krizman
Proteomic analysis of formalin-fixed prostate cancer tissue.
Molecular & cellular proteomics : MCP 2005;4(11):1741-53.
2005: Xia Xu; Timothy D Veenstra; Stephen D Fox; John M Roman; Haleem J Issaq; Roni Falk; Joseph E Saavedra; Larry K Keefer; Regina G Ziegler
Measuring fifteen endogenous estrogens simultaneously in human urine by high-performance liquid chromatography-mass spectrometry.
Analytical chemistry 2005;77(20):6646-54.
2005: Thomas P Conrads; Brian L Hood; Emanuel F Petricoin; Lance A Liotta; Timothy D Veenstra
Cancer proteomics: many technologies, one goal.
Expert review of proteomics 2005;2(5):693-703.
2005: Mark Lowenthal; Arpita I Mehta; Kristina Frogale; Russell W Bandle; Robyn P Araujo; Brian L Hood; Timothy D Veenstra; Thomas P Conrads; Paul Goldsmith; David Fishman; Emanuel F Petricoin; Lance A Liotta
Analysis of albumin-associated peptides and proteins from ovarian cancer patients.
Clinical chemistry 2005;51(10):1933-45.
2005: Brian L Hood; Ming Zhou; King C Chan; David A Lucas; Grace J Kim; Haleem J Issaq; Timothy D Veenstra; Thomas P Conrads
Investigation of the mouse serum proteome.
Journal of proteome research 2005;4(5):1561-8.
2005: Kelly A Conrads; Ming Yi; Kerri A Simpson; David A Lucas; Corinne E Camalier; Li-Rong Yu; Timothy D Veenstra; Robert M Stephens; Thomas P Conrads; George R Beck
A combined proteome and microarray investigation of inorganic phosphate-induced pre-osteoblast cells.
Molecular & cellular proteomics : MCP 2005;4(9):1284-96.
2005: Brian L Hood; David A Lucas; Grace Kim; King C Chan; Josip Blonder; Haleem J Issaq; Timothy D Veenstra; Thomas P Conrads; Ingrid Pollet; Aly Karsan
Quantitative analysis of the low molecular weight serum proteome using 18O stable isotope labeling in a lung tumor xenograft mouse model.
Journal of the American Society for Mass Spectrometry 2005;16(8):1221-30.
2005: Aly Karsan; Bernhard J Eigl; Stephane Flibotte; Karen Gelmon; Philip Switzer; Patricia Hassell; Dorothy Harrison; Jennifer Law; Malcolm Hayes; Moira Stillwell; Zhen Xiao; Thomas P Conrads; Timothy D Veenstra
Analytical and preanalytical biases in serum proteomic pattern analysis for breast cancer diagnosis.
Clinical chemistry 2005;51(8):1525-8.
2005: Satoshi Asano; Jung-Eun Park; Krisada Sakchaisri; Li-Rong Yu; Sukgil Song; Porntip Supavilai; Timothy D Veenstra; Kyung S Lee
Concerted mechanism of Swe1/Wee1 regulation by multiple kinases in budding yeast.
The EMBO journal 2005;24(12):2194-204.
2005: DaRue A Prieto; Brian L Hood; Marlene M Darfler; Thomas G Guiel; David A Lucas; Thomas P Conrads; Timothy D Veenstra; David B Krizman
Liquid Tissue: proteomic profiling of formalin-fixed tissues.
BioTechniques 2005;Suppl():32-5.
2005: Frederieke M Brouwers; Emanuel F Petricoin; Lucia Ksinantova; Jan Breza; Vinodh Rajapakse; Sally Ross; Donald J Johann; Massimo Mannelli; Barry L Shulkin; Richard Kvetnansky; Graeme Eisenhofer; McClellan Walther; Ben A Hitt; Thomas P Conrads; Timothy D Veenstra; David P Mannion; Michael R Wall; G M Wolfe; Vincent A Fusaro; Lance A Liotta; Karel Pacak
Low molecular weight proteomic information distinguishes metastatic from benign pheochromocytoma.
Endocrine-related cancer 2005;12(2):263-72.
2005: Ming Zhou; Thomas P Conrads; Timothy D Veenstra
Proteomics approaches to biomarker detection.
Briefings in functional genomics & proteomics 2005;4(1):69-75.
2005: Timothy D Veenstra; Thomas P Conrads; Brian L Hood; Anthony M Avellino; Richard G Ellenbogen; Richard S Morrison
Biomarkers: mining the biofluid proteome.
Molecular & cellular proteomics : MCP 2005;4(4):409-18.
2005: Haleem J Issaq; King C Chan; George Janini; Thomas P Conrads; Timothy D Veenstra
Multidimensional separation of peptides for effective proteomic analysis.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;817(1):35-47.
2005: Josip Blonder; Martha Hale; King C Chan; Li-Rong Yu; David A Lucas; Thomas P Conrads; Ming Zhou; Michel R Popoff; Haleem J Issaq; Bradley G Stiles; Timothy D Veenstra
Quantitative profiling of the detergent-resistant membrane proteome of iota-b toxin induced vero cells.
Journal of proteome research 2005;4(2):523-31.
2005: Aly Karsan; Josip Blonder; Jennifer Law; Elisa Yaquian; David A Lucas; Thomas P Conrads; Timothy D Veenstra
Proteomic analysis of lipid microdomains from lipopolysaccharide-activated human endothelial cells.
Journal of proteome research 2005;4(2):349-57.
2005: Stephen D Fox; John M Roman; Giovanni Cizza; Timothy D Veenstra; Haleem J Issaq
Quantitative determination of antalarmin, a novel corticotropin-releasing hormone receptor-1 antagonist, in canine plasma by HPLC-MS.
Journal of separation science 2005;28(4):332-6.
2005: Lance A Liotta; Mark Lowenthal; Arpita Mehta; Thomas P Conrads; Timothy D Veenstra; David A Fishman; Emanuel F Petricoin
Importance of communication between producers and consumers of publicly available experimental data.
Journal of the National Cancer Institute 2005;97(4):310-4.
2005: Aly Karsan; Ingrid Pollet; Li-Rong Yu; King C Chan; Thomas P Conrads; David A Lucas; Raymond Andersen; Timothy D Veenstra
Quantitative proteomic analysis of sokotrasterol sulfate-stimulated primary human endothelial cells.
Molecular & cellular proteomics : MCP 2005;4(2):191-204.
2005: Zhen Xiao; DaRue A Prieto; Thomas P Conrads; Timothy D Veenstra; Haleem J Issaq
Proteomic patterns: their potential for disease diagnosis.
Molecular and cellular endocrinology 2005;230(1-2):95-106.
2005: Michele K Dougherty; Jürgen Müller; Daniel A Ritt; Ming Zhou; Xiao Zhen Zhou; Terry D Copeland; Thomas P Conrads; Timothy D Veenstra; Kun Ping Lu; Deborah K Morrison
Regulation of Raf-1 by direct feedback phosphorylation.
Molecular cell 2005;17(2):215-24.
2005: Mark D Johnson; Li-Rong Yu; Thomas P Conrads; Yoshito Kinoshita; Takuma Uo; Joshua K McBee; Timothy D Veenstra; Richard S Morrison
The proteomics of neurodegeneration.
American journal of pharmacogenomics : genomics-related research in drug development and clinical practice 2005;5(4):259-70.
2005: Oleg Chertov; John T Simpson; Arya Biragyn; Thomas P Conrads; Timothy D Veenstra; Robert J Fisher
Enrichment of low-molecular-weight proteins from biofluids for biomarker discovery.
Expert review of proteomics 2005;2(1):139-45.
2004: Haleem J Issaq; George Janini; King C Chan; Timothy D Veenstra
Sheathless electrospray ionization interfaces for capillary electrophoresis-mass spectrometric detection advantages and limitations.
Journal of chromatography. A 2004;1053(1-2):37-42.
2004: Timothy D Veenstra; DaRue A Prieto; Thomas P Conrads
Proteomic patterns for early cancer detection.
Drug discovery today 2004;9(20):889-97.
2004: Xia Xu; Larry K Keefer; David J Waterhouse; Joseph E Saavedra; Timothy D Veenstra; Regina G Ziegler
Measuring seven endogenous ketolic estrogens simultaneously in human urine by high-performance liquid chromatography-mass spectrometry.
Analytical chemistry 2004;76(19):5829-36.
2004: Josip Blonder; Atsushi Terunuma; Thomas P Conrads; King C Chan; Carole Yee; David A Lucas; Carl F Schaefer; Li-Rong Yu; Haleem J Issaq; Timothy D Veenstra; Jonathan C Vogel
A proteomic characterization of the plasma membrane of human epidermis by high-throughput mass spectrometry.
The Journal of investigative dermatology 2004;123(4):691-9.
2004: David K Ornstein; Walter Rayford; Vincent A Fusaro; Thomas P Conrads; Sally J Ross; Ben A Hitt; Wesley W Wiggins; Timothy D Veenstra; Lance A Liotta; Emanuel F Petricoin
Serum proteomic profiling can discriminate prostate cancer from benign prostates in men with total prostate specific antigen levels between 2.5 and 15.0 ng/ml.
The Journal of urology 2004;172(4 Pt 1):1302-5.
2004: Li-Rong Yu; Thomas P Conrads; Takuma Uo; Yoshito Kinoshita; Richard S Morrison; David A Lucas; King C Chan; Josip Blonder; Haleem J Issaq; Timothy D Veenstra
Global analysis of the cortical neuron proteome.
Molecular & cellular proteomics : MCP 2004;3(9):896-907.
2004: Susan K Keay; Zoltan Szekely; Thomas P Conrads; Timothy D Veenstra; Joseph J Barchi; Chen-Ou Zhang; Kristopher R Koch; Christopher J Michejda
An antiproliferative factor from interstitial cystitis patients is a frizzled 8 protein-related sialoglycopeptide.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(32):11803-8.
2004: Josip Blonder; Thomas P Conrads; Timothy D Veenstra
Characterization and quantitation of membrane proteomes using multidimensional MS-based proteomic technologies.
Expert review of proteomics 2004;1(2):153-63.
2004: Emanuel F Petricoin; David A Fishman; Thomas P Conrads; Timothy D Veenstra; Lance A Liotta
Lessons from Kitty Hawk: from feasibility to routine clinical use for the field of proteomic pattern diagnostics.
Proteomics 2004;4(8):2357-60.
2004: Josip Blonder; Maria Cecilia Rodriguez-Galan; King C Chan; David A Lucas; Li-Rong Yu; Thomas P Conrads; Haleem J Issaq; Howard A Young; Timothy D Veenstra
Analysis of murine natural killer cell microsomal proteins using two-dimensional liquid chromatography coupled to tandem electrospray ionization mass spectrometry.
Journal of proteome research 2004;3(4):862-70.
2004: George Janini; King C Chan; Thomas P Conrads; Haleem J Issaq; Timothy D Veenstra
Two-dimensional liquid chromatography-capillary zone electrophoresis-sheathless electrospray ionization-mass spectrometry: evaluation for peptide analysis and protein identification.
Electrophoresis 2004;25(13):1973-80.
2004: Mark D Johnson; Li-Rong Yu; Thomas P Conrads; Yoshito Kinoshita; Takuma Uo; Jesse D Matthews; Sang-Won Lee; Richard D Smith; Timothy D Veenstra; Richard S Morrison
Proteome analysis of DNA damage-induced neuronal death using high throughput mass spectrometry.
The Journal of biological chemistry 2004;279(25):26685-97.
2004: Donald J Johann; Michael D McGuigan; Amit R Patel; Stanimire Tomov; Sally Ross; Thomas P Conrads; Timothy D Veenstra; David A Fishman; Gordon R Whiteley; Emanuel F Petricoin; Lance A Liotta
Clinical proteomics and biomarker discovery.
Annals of the New York Academy of Sciences 2004;1022():295-305.
2004: Thomas P Conrads; Vincent A Fusaro; Sally Ross; Donald J Johann; Vinodh Rajapakse; Ben A Hitt; Seth M Steinberg; Elise C Kohn; David A Fishman; G Whitely; J C Barrett; Lance A Liotta; Emanuel F Petricoin; Timothy D Veenstra
High-resolution serum proteomic features for ovarian cancer detection.
Endocrine-related cancer 2004;11(2):163-78.
2004: Li-Rong Yu; Thomas P Conrads; Takuma Uo; Haleem J Issaq; Richard S Morrison; Timothy D Veenstra
Evaluation of the acid-cleavable isotope-coded affinity tag reagents: application to camptothecin-treated cortical neurons.
Journal of proteome research 2004;3(3):469-77.
2004: Kelly A Conrads; Li-Rong Yu; David A Lucas; Ming Zhou; King C Chan; Kerri A Simpson; Carl F Schaefer; Haleem J Issaq; Timothy D Veenstra; George R Beck; Thomas P Conrads
Quantitative proteomic analysis of inorganic phosphate-induced murine MC3T3-E1 osteoblast cells.
Electrophoresis 2004;25(9):1342-52.
2004: Josip Blonder; Martha Hale; David A Lucas; Carl F Schaefer; Li-Rong Yu; Thomas P Conrads; Haleem J Issaq; Bradley G Stiles; Timothy D Veenstra
Proteomic analysis of detergent-resistant membrane rafts.
Electrophoresis 2004;25(9):1307-18.
2004: Ming Zhou; David A Lucas; King C Chan; Haleem J Issaq; Emanuel F Petricoin; Lance A Liotta; Timothy D Veenstra; Thomas P Conrads
An investigation into the human serum "interactome".
Electrophoresis 2004;25(9):1289-98.
2004: Timothy D Veenstra; Thomas P Conrads; Haleem J Issaq
What to do with "one-hit wonders"?
Electrophoresis 2004;25(9):1278-9.
2004: Zhen Xiao; Brian T Luke; Grant Izmirlian; Asad Umar; Patrick M Lynch; R K S Phillips; Sherri Patterson; Thomas P Conrads; Timothy D Veenstra; Peter Greenwald; Ernest T Hawk; Iqbal Unnisa Ali
Serum proteomic profiles suggest celecoxib-modulated targets and response predictors.
Cancer research 2004;64(8):2904-9.
2004: Josip Blonder; Maria Cecilia Rodriguez-Galan; David A Lucas; Howard A Young; Haleem J Issaq; Timothy D Veenstra; Thomas P Conrads
Proteomic investigation of natural killer cell microsomes using gas-phase fractionation by mass spectrometry.
Biochimica et biophysica acta 2004;1698(1):87-95.
2004: Oleg Chertov; Arya Biragyn; Larry W Kwak; John T Simpson; Tatiana Boronina; Van M Hoang; DaRue A Prieto; Thomas P Conrads; Timothy D Veenstra; Robert J Fisher
Organic solvent extraction of proteins and peptides from serum as an effective sample preparation for detection and identification of biomarkers by mass spectrometry.
Proteomics 2004;4(4):1195-203.
2004: Krisada Sakchaisri; Satoshi Asano; Li-Rong Yu; Mark J Shulewitz; Chong J Park; Jung-Eun Park; Young-Wook Cho; Timothy D Veenstra; Jeremy Thorner; Kyung S Lee
Coupling morphogenesis to mitotic entry.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(12):4124-9.
2004: Emanuel F Petricoin; Vinodh Rajapaske; Eugene H Herman; Ali M Arekani; Sally Ross; Donald J Johann; Alan Knapton; Jun Zhang; Ben A Hitt; Thomas P Conrads; Timothy D Veenstra; Lance A Liotta; Frank D Sistare
Toxicoproteomics: serum proteomic pattern diagnostics for early detection of drug induced cardiac toxicities and cardioprotection.
Toxicologic pathology 2004;32 Suppl 1():122-30.
2004: Thomas P Conrads; Timothy D Veenstra
The utility of proteomic patterns for the diagnosis of cancer.
Current drug targets. Immune, endocrine and metabolic disorders 2004;4(1):41-50.
2004: berman david; Ie-Ming Shih; Lorri-Anne Burke; Timothy D Veenstra; Yingming Zhao; Thomas P Conrads; Sung Won Kwon; Van Hoang; Li-Rong Yu; Ming Zhou; Robert J Kurman; Emanuel F Petricoin; Lance A Liotta
Profiling the activity of G proteins in patient-derived tissues by rapid affinity-capture of signal transduction proteins (GRASP).
Proteomics 2004;4(3):812-8.
2004: Haiyan Yang; Jessica Rouse; Luanne Lukes; Mindy Lancaster; Timothy D Veenstra; Ming Zhou; Ying Shi; Yeong-Gwan Park; Kent Hunter
Caffeine suppresses metastasis in a transgenic mouse model: a prototype molecule for prophylaxis of metastasis.
Clinical & experimental metastasis 2004;21(8):719-35.
2004: Thomas P Conrads; Brian L Hood; Haleem J Issaq; Timothy D Veenstra
Proteomic patterns as a diagnostic tool for early-stage cancer: a review of its progress to a clinically relevant tool.
Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology 2004;8(2):77-85.
2004: Josip Blonder; Thomas P Conrads; Li-Rong Yu; Atsushi Terunuma; George Janini; Haleem J Issaq; Jonathan C Vogel; Timothy D Veenstra
A detergent- and cyanogen bromide-free method for integral membrane proteomics: application to Halobacterium purple membranes and the human epidermal membrane proteome.
Proteomics 2004;4(1):31-45.
2004: Zhen Xiao; Thomas P Conrads; David A Lucas; George Janini; Carl F Schaefer; Kenneth H Buetow; Haleem J Issaq; Timothy D Veenstra
Direct ampholyte-free liquid-phase isoelectric peptide focusing: application to the human serum proteome.
Electrophoresis 2004;25(1):128-33.
2003: Timothy D Veenstra; Thomas P Conrads
Serum protein fingerprinting.
Current opinion in molecular therapeutics 2003;5(6):584-93.
2003: Sunil R Hingorani; Emanuel F Petricoin; Anirban Maitra; Vinodh Rajapakse; Catrina King; Michael Jacobetz; Sally Ross; Thomas P Conrads; Timothy D Veenstra; Ben A Hitt; Yoshiya Kawaguchi; Donald J Johann; Lance A Liotta; Howard C Crawford; Mary E Putt; Tyler Jacks; Christopher V E Wright; Ralph Hruban; Andrew M Lowy; David A Tuveson
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse.
Cancer cell 2003;4(6):437-50.
2003: Stephen D Fox; Richard A Lempicki; Douglas A Hosack; Michael Baseler; Joseph A Kovacs; H Clifford Lane; Timothy D Veenstra; Haleem J Issaq
A comparison of microLC/electrospray ionization-MS and GC/MS for the measurement of stable isotope enrichment from a [2H2]-glucose metabolic probe in T-cell genomic DNA.
Analytical chemistry 2003;75(23):6517-22.
2003: George Janini; Ming Zhou; Li-Rong Yu; Josip Blonder; Michelle Gignac; Thomas P Conrads; Haleem J Issaq; Timothy D Veenstra
On-column sample enrichment for capillary electrophoresis sheathless electrospray ionization mass spectrometry: evaluation for peptide analysis and protein identification.
Analytical chemistry 2003;75(21):5984-93.
2003: Radhakrishna S Tirumalai; King C Chan; DaRue A Prieto; Haleem J Issaq; Thomas P Conrads; Timothy D Veenstra
Characterization of the low molecular weight human serum proteome.
Molecular & cellular proteomics : MCP 2003;2(10):1096-103.
2003: Gordon R Macpherson; Sylvia S W Ng; Siiri L Forbes; Giovanni Melillo; Tatiana S Karpova; James McNally; Thomas P Conrads; Timothy D Veenstra; Alfredo Martinez; Frank Cuttitta; Douglas K Price; William D Figg
Anti-angiogenic activity of human endostatin is HIF-1-independent in vitro and sensitive to timing of treatment in a human saphenous vein assay.
Molecular cancer therapeutics 2003;2(9):845-54.
2003: Van M Hoang; Thomas P Conrads; Timothy D Veenstra; Josip Blonder; Atsushi Terunuma; Jonathan C Vogel; Robert J Fisher
Quantitative proteomics employing primary amine affinity tags.
Journal of biomolecular techniques : JBT 2003;14(3):216-23.
2003: Thomas P Conrads; Ming Zhou; Emanuel F Petricoin; Lance A Liotta; Timothy D Veenstra
Cancer diagnosis using proteomic patterns.
Expert review of molecular diagnostics 2003;3(4):411-20.
2003: George Janini; Thomas P Conrads; Timothy D Veenstra; Haleem J Issaq
Development of a two-dimensional protein-peptide separation protocol for comprehensive proteome measurements.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;787(1):43-51.
2003: George Janini; Thomas P Conrads; Kenneth L Wilkens; Haleem J Issaq; Timothy D Veenstra
A sheathless nanoflow electrospray interface for on-line capillary electrophoresis mass spectrometry.
Analytical chemistry 2003;75(7):1615-9.
2003: Haleem J Issaq; Thomas P Conrads; DaRue A Prieto; Radhakrishna Tirumalai; Timothy D Veenstra
SELDI-TOF MS for diagnostic proteomics.
Analytical chemistry 2003;75(7):148A-155A.
2003: Que N Van; Gwendolyn N Chmurny; Timothy D Veenstra
The depletion of protein signals in metabonomics analysis with the WET-CPMG pulse sequence.
Biochemical and biophysical research communications 2003;301(4):952-9.
2003: Li-Rong Yu; Ming Zhou; Thomas P Conrads; Timothy D Veenstra
Diagnostic proteomics: serum proteomic patterns for the detection of early stage cancers.
Disease markers 2003;19(4-5):209-18.
2003: Donald J Johann; Michael D McGuigan; Stanimire Tomov; Vincent A Fusaro; Sally Ross; Thomas P Conrads; Timothy D Veenstra; David A Fishman; Gordon R Whiteley; Emanuel F Petricoin; Lance A Liotta
Novel approaches to visualization and data mining reveals diagnostic information in the low amplitude region of serum mass spectra from ovarian cancer patients.
Disease markers 2003;19(4-5):197-207.
2003: Que N Van; John R Klose; David A Lucas; DaRue A Prieto; Brian T Luke; Jack Collins; Stanley K Burt; Gwendolyn N Chmurny; Haleem J Issaq; Thomas P Conrads; Timothy D Veenstra; Susan K Keay
The use of urine proteomic and metabonomic patterns for the diagnosis of interstitial cystitis and bacterial cystitis.
Disease markers 2003;19(4-5):169-83.
2003: Timothy D Veenstra
Proteome analysis of posttranslational modifications.
Advances in protein chemistry 2003;65():161-94.
2002: Haleem J Issaq; Thomas P Conrads; George Janini; Timothy D Veenstra
Methods for fractionation, separation and profiling of proteins and peptides.
Electrophoresis 2002;23(17):3048-61.
2002: Richard S Morrison; Yoshito Kinoshita; Mark D Johnson; Takuma Uo; Joseph T Ho; Joshua K McBee; Thomas P Conrads; Timothy D Veenstra
Proteomic analysis in the neurosciences.
Molecular & cellular proteomics : MCP 2002;1(8):553-60.
2002: Haleem J Issaq; Timothy D Veenstra; Thomas P Conrads; Donna Felschow
The SELDI-TOF MS approach to proteomics: protein profiling and biomarker identification.
Biochemical and biophysical research communications 2002;292(3):587-92.
2002: Thomas P Conrads; Haleem J Issaq; Timothy D Veenstra
New tools for quantitative phosphoproteome analysis.
Biochemical and biophysical research communications 2002;290(3):885-90.