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Maria Veiga-da-Cunha

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Genes & Molecular Sequences

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Emile Van Schaftingen; Maria Veiga-da-Cunha; François Collard; Alexandre Marbaix; Rim Rzem; Carole L Linster
Metabolite proofreading, a neglected aspect of intermediary metabolism.
Emile Van Schaftingen; François Collard; Elsa Wiame; Maria Veiga-da-Cunha
Enzymatic repair of Amadori products.
Maria Veiga-da-Cunha; Thomas Balligand; Farah Hadi; Vincent Stroobant; Emile Van Schaftingen
Molecular identification of hydroxylysine kinase and of ammoniophospholyases acting on 5-phosphohydroxy-L-lysine and phosphoethanolamine.

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All Publications

2013: Emile Van Schaftingen; Maria Veiga-da-Cunha; François Collard; Alexandre Marbaix; Rim Rzem; Carole L Linster
Metabolite proofreading, a neglected aspect of intermediary metabolism.
Journal of inherited metabolic disease 2013;36(3):427-34.
2012: Emile Van Schaftingen; François Collard; Elsa Wiame; Maria Veiga-da-Cunha
Enzymatic repair of Amadori products.
Amino acids 2012;42(4):1143-50.
2012: Maria Veiga-da-Cunha; Thomas Balligand; Farah Hadi; Vincent Stroobant; Emile Van Schaftingen
Molecular identification of hydroxylysine kinase and of ammoniophospholyases acting on 5-phosphohydroxy-L-lysine and phosphoethanolamine.
The Journal of biological chemistry 2012;287(10):7246-55.
2010: Maria Veiga-da-Cunha; Donatienne Tyteca; Vincent Stroobant; Pierre J Courtoy; Fred R Opperdoes; Emile Van Schaftingen
Molecular identification of NAT8 as the enzyme that acetylates cysteine S-conjugates to mercapturic acids.
The Journal of biological chemistry 2010;285(24):18888-98.
2010: Jakub Drozak; Maria Veiga-da-Cunha; Didier Vertommen; Vincent Stroobant; Emile Van Schaftingen
Molecular identification of carnosine synthase as ATP-grasp domain-containing protein 1 (ATPGD1).
The Journal of biological chemistry 2010;285(13):9346-56.
2010: S M A Pascal; Maria Veiga-da-Cunha; Patrick Gilon; E Van Schaftingen; Jean-Christophe Jonas
Effects of fructosamine-3-kinase deficiency on function and survival of mouse pancreatic islets after prolonged culture in high glucose or ribose concentrations.
American journal of physiology. Endocrinology and metabolism 2010;298(3):E586-96.
2009: Maria Veiga-da-Cunha; Tatiana Sokolova; Fred Opperdoes; Emile Van Schaftingen
Evolution of vertebrate glucokinase regulatory protein from a bacterial N-acetylmuramate 6-phosphate etherase.
The Biochemical journal 2009;423(3):323-32.
2009: Stéphane Jaisson; Maria Veiga-da-Cunha; Emile Van Schaftingen
Molecular identification of omega-amidase, the enzyme that is functionally coupled with glutamine transaminases, as the putative tumor suppressor Nit2.
Biochimie 2009;91(9):1066-71.
2009: Emile Van Schaftingen; Rim Rzem; Maria Veiga-da-Cunha
L: -2-Hydroxyglutaric aciduria, a disorder of metabolite repair.
Journal of inherited metabolic disease 2009;32(2):135-42.
2008: Maria Veiga-da-Cunha; Wendy Vleugels; Pushpa Maliekal; Gert Matthijs; Emile Van Schaftingen
Mammalian phosphomannomutase PMM1 is the brain IMP-sensitive glucose-1,6-bisphosphatase.
The Journal of biological chemistry 2008;283(49):33988-93.
2008: Tamás Kardon; Vincent Stroobant; Maria Veiga-da-Cunha; Emile Van Schaftingen
Characterization of mammalian sedoheptulokinase and mechanism of formation of erythritol in sedoheptulokinase deficiency.
FEBS letters 2008;582(23-24):3330-4.
2007: Pushpa Maliekal; Tatiana Sokolova; Didier Vertommen; Maria Veiga-da-Cunha; Emile Van Schaftingen
Molecular identification of mammalian phosphopentomutase and glucose-1,6-bisphosphate synthase, two members of the alpha-D-phosphohexomutase family.
The Journal of biological chemistry 2007;282(44):31844-51.
2007: Rim Rzem; M-F Vincent; Emile Van Schaftingen; Maria Veiga-da-Cunha
L-2-hydroxyglutaric aciduria, a defect of metabolite repair.
Journal of inherited metabolic disease 2007;30(5):681-9.
2007: Rita Gemayel; Juliette Fortpied; Rim Rzem; Didier Vertommen; Maria Veiga-da-Cunha; Emile Van Schaftingen
Many fructosamine 3-kinase homologues in bacteria are ribulosamine/erythrulosamine 3-kinases potentially involved in protein deglycation.
The FEBS journal 2007;274(17):4360-74.
2007: Emile Van Schaftingen; Ghislain Delpierre; François Collard; Juliette Fortpied; Rita Gemayel; Elsa Wiame; Maria Veiga-da-Cunha
Fructosamine 3-kinase and other enzymes involved in protein deglycation.
Advances in enzyme regulation 2007;47():261-9.
2006: Maria Veiga-da-Cunha; Patrick Jacquemin; Ghislain Delpierre; Catherine Godfraind; Ivan Théate; Didier Vertommen; Frédéric Clotman; Frédéric P Lemaigre; Olivier Devuyst; Emile Van Schaftingen
Increased protein glycation in fructosamine 3-kinase-deficient mice.
The Biochemical journal 2006;399(2):257-64.
2006: Ghislain Delpierre; Maria Veiga-da-Cunha; Didier Vertommen; M Buysschaert; Emile Van Schaftingen
Variability in erythrocyte fructosamine 3-kinase activity in humans correlates with polymorphisms in the FN3K gene and impacts on haemoglobin glycation at specific sites.
Diabetes & metabolism 2006;32(1):31-9.
2006: Rim Rzem; Emile Van Schaftingen; Maria Veiga-da-Cunha
The gene mutated in l-2-hydroxyglutaric aciduria encodes l-2-hydroxyglutarate dehydrogenase.
Biochimie 2006;88(1):113-6.
2005: Charlotte Barrière; Maria Veiga-da-Cunha; Nicolas Pons; Eric Guédon; Sacha A F T van Hijum; Jan Kok; Oscar P Kuipers; Dusko S Ehrlich; Pierre Renault
Fructose utilization in Lactococcus lactis as a model for low-GC gram-positive bacteria: its regulator, signal, and DNA-binding site.
Journal of bacteriology 2005;187(11):3752-61.
2005: Anna L Gloyn; Stella Odili; Dorothy Zelent; Carol Buettger; Harriet A J Castleden; Anna M Steele; Amanda Stride; Chiyo Shiota; Mark Magnuson; Renata Lorini; Giuseppe d'Annunzio; Charles A Stanley; Jae Kwagh; Emile Van Schaftingen; Maria Veiga-da-Cunha; Fabrizio Barbetti; Pete Dunten; Yi Han; Joseph Grimsby; Rebecca Taub; Sian Ellard; Andrew T Hattersley; Franz M Matschinsky
Insights into the structure and regulation of glucokinase from a novel mutation (V62M), which causes maturity-onset diabetes of the young.
The Journal of biological chemistry 2005;280(14):14105-13.
2004: Rim Rzem; Maria Veiga-da-Cunha; Gaëtane Noël; Sophie Goffette; Marie-Cécile Nassogne; Brahim Tabarki; Christina Schöller; Thorsten Marquardt; Miikka Vikkula; Emile Van Schaftingen
A gene encoding a putative FAD-dependent L-2-hydroxyglutarate dehydrogenase is mutated in L-2-hydroxyglutaric aciduria.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(48):16849-54.
2004: Caroline Smal; Luc Bertrand; Eric Van Den Neste; Sabine Cardoen; Maria Veiga-da-Cunha; Sandrine Marie; V Race; Augustin Ferrant; Georges Van den Berghe; Françoise Bontemps
New evidences for a regulation of deoxycytidine kinase activity by reversible phosphorylation.
Nucleosides, nucleotides & nucleic acids 2004;23(8-9):1363-5.
2004: Younes Achouri; Gaëtane Noël; Didier Vertommen; Mark H Rider; Maria Veiga-da-Cunha; Emile Van Schaftingen
Identification of a dehydrogenase acting on D-2-hydroxyglutarate.
The Biochemical journal 2004;381(Pt 1):35-42.
2004: Maria Veiga-da-Cunha; Jean Francois Collet; Benoît Prieur; Jaak Jaeken; Yves Peeraer; Anja Rabbijns; Emile Van Schaftingen
Mutations responsible for 3-phosphoserine phosphatase deficiency.
European journal of human genetics : EJHG 2004;12(2):163-6.
2003: Maria Veiga-da-Cunha; Jérôme Delplanque; A Gillain; D T Bonthron; Philippe Boutin; Emile Van Schaftingen; philippe froguel
Mutations in the glucokinase regulatory protein gene in 2p23 in obese French caucasians.
Diabetologia 2003;46(5):704-11.
2002: Maria Veiga-da-Cunha; Emile Van Schaftingen
Identification of fructose 6-phosphate- and fructose 1-phosphate-binding residues in the regulatory protein of glucokinase.
The Journal of biological chemistry 2002;277(10):8466-73.
2000: Brent W Weston; J L Lin; Joseph Muenzer; H S Cameron; Roland R Arnold; Hans H Seydewitz; E Mayatepek; Emile Van Schaftingen; Maria Veiga-da-Cunha; Dietrich Matern; Y T Chen
Glucose-6-phosphatase mutation G188R confers an atypical glycogen storage disease type 1b phenotype.
Pediatric research 2000;48(3):329-34.
2000: Maria Veiga-da-Cunha; A Hoyoux; Emile Van Schaftingen; A Houyoux
Overexpression and purification of fructose-1-phosphate kinase from Escherichia coli: application to the assay of fructose 1-phosphate.
Protein expression and purification 2000;19(1):48-52.
2000: Maria Veiga-da-Cunha; Isabelle Gerin; Emile Van Schaftingen
How many forms of glycogen storage disease type I?
European journal of pediatrics 2000;159(5):314-8.
2000: M A Moukil; Maria Veiga-da-Cunha; Emile Van Schaftingen
Study of the regulatory properties of glucokinase by site-directed mutagenesis: conversion of glucokinase to an enzyme with high affinity for glucose.
Diabetes 2000;49(2):195-201.
1999: François Collard; Jean Francois Collet; Isabelle Gerin; Maria Veiga-da-Cunha; Emile Van Schaftingen
Identification of the cDNA encoding human 6-phosphogluconolactonase, the enzyme catalyzing the second step of the pentose phosphate pathway(1).
FEBS letters 1999;459(2):223-6.
1999: Maria Veiga-da-Cunha; Isabelle Gerin; Y T Chen; P J Lee; J V Leonard; I Maire; U Wendel; Miikka Vikkula; Emile Van Schaftingen
The putative glucose 6-phosphate translocase gene is mutated in essentially all cases of glycogen storage disease type I non-a.
European journal of human genetics : EJHG 1999;7(6):717-23.
1999: Núria de la Iglesia; Maria Veiga-da-Cunha; Emile Van Schaftingen; Joan J Guinovart; Juan C Ferrer
Glucokinase regulatory protein is essential for the proper subcellular localisation of liver glucokinase.
FEBS letters 1999;456(2):332-8.
1999: A Follens; Maria Veiga-da-Cunha; Roel Merckx; Emile Van Schaftingen; Johan Van Eldere
acs1 of Haemophilus influenzae type a capsulation locus region II encodes a bifunctional ribulose 5-phosphate reductase- CDP-ribitol pyrophosphorylase.
Journal of bacteriology 1999;181(7):2001-7.
1999: Isabelle Gerin; Maria Veiga-da-Cunha; G Noël; Emile Van Schaftingen
Structure of the gene mutated in glycogen storage disease type Ib.
Gene 1999;227(2):189-95.
1998: Maria Veiga-da-Cunha; Isabelle Gerin; Y T Chen; T de Barsy; P de Lonlay; Carlo Dionisi Vici; C D Fenske; P J Lee; J V Leonard; I Maire; A McConkie-Rosell; S Schweitzer; Miikka Vikkula; Emile Van Schaftingen
A gene on chromosome 11q23 coding for a putative glucose- 6-phosphate translocase is mutated in glycogen-storage disease types Ib and Ic.
American journal of human genetics 1998;63(4):976-83.
1997: Isabelle Gerin; Maria Veiga-da-Cunha; Younes Achouri; Jean Francois Collet; Emile Van Schaftingen
Sequence of a putative glucose 6-phosphate translocase, mutated in glycogen storage disease type Ib.
FEBS letters 1997;419(2-3):235-8.
1997: Jean Francois Collet; Isabelle Gerin; Mark H Rider; Maria Veiga-da-Cunha; Emile Van Schaftingen
Human L-3-phosphoserine phosphatase: sequence, expression and evidence for a phosphoenzyme intermediate.
FEBS letters 1997;408(3):281-4.
1997: Gert Matthijs; Els Schollen; E Pardon; Maria Veiga-da-Cunha; Jaak Jaeken; Jean-Jacques Cassiman; Emile Van Schaftingen
Mutations in PMM2, a phosphomannomutase gene on chromosome 16p13, in carbohydrate-deficient glycoprotein type I syndrome (Jaeken syndrome).
Nature genetics 1997;16(1):88-92.
1997: Emile Van Schaftingen; Maria Veiga-da-Cunha; L Niculescu
The regulatory protein of glucokinase.
Biochemical Society transactions 1997;25(1):136-40.
1997: L Niculescu; Maria Veiga-da-Cunha; Emile Van Schaftingen
Investigation on the mechanism by which fructose, hexitols and other compounds regulate the translocation of glucokinase in rat hepatocytes.
The Biochemical journal 1997;321 ( Pt 1)():239-46.
1996: Maria Veiga-da-Cunha; L Z Xu; Y H Lee; D Marotta; S J Pilkis; Emile Van Schaftingen
Effect of mutations on the sensitivity of human beta-cell glucokinase to liver regulatory protein.
Diabetologia 1996;39(10):1173-9.
1996: L Niculescu; Maria Veiga-da-Cunha; Emile Van Schaftingen
Enzymatic assays of fructose-1-phosphate and fructose-1,6-bisphosphate in the picomole range.
Analytical biochemistry 1996;235(2):243-44.
1996: Maria Veiga-da-Cunha; S Courtois; A Michel; E Gosselain; Emile Van Schaftingen
Amino acid conservation in animal glucokinases. Identification of residues implicated in the interaction with the regulatory protein.
The Journal of biological chemistry 1996;271(11):6292-7.
1994: Maria Veiga-da-Cunha; Michel detheux; N Watelet; Emile Van Schaftingen
Cloning and expression of a Xenopus liver cDNA encoding a fructose-phosphate-insensitive regulatory protein of glucokinase.
European journal of biochemistry / FEBS 1994;225(1):43-51.
1994: Emile Van Schaftingen; Michel detheux; Maria Veiga-da-Cunha
Short-term control of glucokinase activity: role of a regulatory protein.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1994;8(6):414-9.
1993: Maria Veiga-da-Cunha; Helena Santos; Emile Van Schaftingen
Pathway and regulation of erythritol formation in Leuconostoc oenos.
Journal of bacteriology 1993;175(13):3941-8.