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Nik Veldhoen

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Metamorphosis, Biological

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S Austin Hammond; Michelle D Boone; Jameson Jordan; Marek Kobylarz; Vicki Rehaume; Nik Veldhoen; Nicholas R Webber; Caren C Helbing
Characterization of Gene Expression Endpoints During Postembryonic Development of the Northern Green Frog (Rana clamitans melanota).
Michelle D Boone; S Austin Hammond; Nik Veldhoen; Melissa Youngquist; Caren C Helbing
Specific time of exposure during tadpole development influences biological effects of the insecticide carbaryl in green frogs (Lithobates clamitans).
Nik Veldhoen; Cory Dubetz; Michael G Ikonomou; David A Patterson; Vicki Rehaume; Caren C Helbing
Evidence of disruption in estrogen-associated signaling in the liver transcriptome of in-migrating sockeye salmon of British Columbia, Canada.

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All Publications

2013: S Austin Hammond; Michelle D Boone; Jameson Jordan; Marek Kobylarz; Vicki Rehaume; Nik Veldhoen; Nicholas R Webber; Caren C Helbing
Characterization of Gene Expression Endpoints During Postembryonic Development of the Northern Green Frog (Rana clamitans melanota).
Zoological science 2013;30(5):392-401.
2013: Michelle D Boone; S Austin Hammond; Nik Veldhoen; Melissa Youngquist; Caren C Helbing
Specific time of exposure during tadpole development influences biological effects of the insecticide carbaryl in green frogs (Lithobates clamitans).
Aquatic toxicology (Amsterdam, Netherlands) 2013;130-131():139-48.
2013: Nik Veldhoen; Cory Dubetz; Michael G Ikonomou; David A Patterson; Vicki Rehaume; Caren C Helbing
Evidence of disruption in estrogen-associated signaling in the liver transcriptome of in-migrating sockeye salmon of British Columbia, Canada.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2013;157(2):150-61.
2013: Vicki L Marlatt; Vicki Rehaume; Dayue Shang; Rachel C Skirrow; Kurtis Vallée; Graham C van Aggelen; Nik Veldhoen; Dannika Bakker; James R Elphick; Maxine Haberl; Bonnie P Lo; Caren C Helbing
Triclosan exposure alters postembryonic development in a Pacific tree frog (Pseudacris regilla) Amphibian Metamorphosis Assay (TREEMA).
Aquatic toxicology (Amsterdam, Netherlands) 2013;126():85-94.
2012: Brian T Searcy; Jenifer Soto-Pena; Phillip Stafford; Nik Veldhoen; James S Beckstrom-Sternberg; Stephen Beckstrom-Sternberg; Caren C Helbing; Michael C Owen; Joel Phillips; Claire Ramirez; Angela L Schwendiman; Catherine R Propper
Thyroid hormone-dependent development in Xenopus laevis: a sensitive screen of thyroid hormone signaling disruption by municipal wastewater treatment plant effluent.
General and comparative endocrinology 2012;176(3):481-92.
2012: Nik Veldhoen; Craig Buday; Melissa Cabecinha; Jon Chamberlain; Cory Dubetz; Michael G Ikonomou; Jameson Jordan; Sabrina Pittroff; Vicki Rehaume; Kurtis Vallée; Graham Van Aggelen; Caren C Helbing
Biological effects of the anti-parasitic chemotherapeutant emamectin benzoate on a non-target crustacean, the spot prawn (Pandalus platyceros Brandt, 1851) under laboratory conditions.
Aquatic toxicology (Amsterdam, Netherlands) 2012;108():94-105.
2012: Nik Veldhoen; Michael G Ikonomou; Caren C Helbing
Molecular profiling of marine fauna: integration of omics with environmental assessment of the world's oceans.
Ecotoxicology and environmental safety 2012;76(2):23-38.
2011: Andrea H Buckman; Graeme Ellis; John K B Ford; Caren C Helbing; Nik Veldhoen; Peter S Ross
PCB-associated changes in mRNA expression in killer whales (Orcinus orca) from the NE Pacific Ocean.
Environmental science & technology 2011;45(23):10194-202.
2011: Caren C Helbing; Catherine R Propper; Nik Veldhoen
Triclosan affects the thyroid axis of amphibians.
Toxicological sciences : an official journal of the Society of Toxicology 2011;123(2):601-2; author reply 603-5.
2011: Nik Veldhoen; Adrian M H Debruyn; Marek Kobylarz; Christopher J Lowe; Lizanne Meloche; Caren C Helbing
Relationship between mRNA biomarker candidates and location near a marine municipal wastewater outfall in the benthic indicator species Modiolus modiolus (L.).
Aquatic toxicology (Amsterdam, Netherlands) 2011;105(1-2):119-26.
2011: Mark P Gunderson; Nik Veldhoen; Rachel C Skirrow; Magnus K Macnab; Wei Ding; Graham Van Aggelen; Caren C Helbing
Effect of low dose exposure to the herbicide atrazine and its metabolite on cytochrome P450 aromatase and steroidogenic factor-1 mRNA levels in the brain of premetamorphic bullfrog tadpoles (Rana catesbeiana).
Aquatic toxicology (Amsterdam, Netherlands) 2011;102(1-2):31-8.
2011: Caren C Helbing; Graham Van Aggelen; Nik Veldhoen
Triclosan affects thyroid hormone-dependent metamorphosis in anurans.
Toxicological sciences : an official journal of the Society of Toxicology 2011;119(2):417-8; author reply 419-22.
2010: Ashley Hinther; Saadia Vawda; Rachel C Skirrow; Nik Veldhoen; Patricia Collins; Jay T Cullen; Graham Van Aggelen; Caren C Helbing
Nanometals induce stress and alter thyroid hormone action in amphibia at or below North American water quality guidelines.
Environmental science & technology 2010;44(21):8314-21.
2010: Nik Veldhoen; Michael G Ikonomou; Cory Dubetz; Nancy Macpherson; Tracy Sampson; Barry C Kelly; Caren C Helbing
Gene expression profiling and environmental contaminant assessment of migrating Pacific salmon in the Fraser River watershed of British Columbia.
Aquatic toxicology (Amsterdam, Netherlands) 2010;97(3):212-25.
2009: Nik Veldhoen; Christopher J Lowe; Céline Davis; Asit Mazumder; Caren C Helbing
Gene expression profiling in the deep water horse mussel Modiolus modiolus (L.) located near a marine municipal wastewater outfall.
Aquatic toxicology (Amsterdam, Netherlands) 2009;93(2-3):116-24.
2009: Deanna Dryhurst; Toyotaka Ishibashi; Kristie L Rose; Jose Maria Eirín-López; Darin McDonald; Begonia Silva-Moreno; Nik Veldhoen; Caren C Helbing; Michael J Hendzel; Jeffrey Shabanowitz; Donald F Hunt; Juan Ausió
Characterization of the histone H2A.Z-1 and H2A.Z-2 isoforms in vertebrates.
BMC biology 2009;7():86.
2008: Rachel C Skirrow; Nik Veldhoen; Dominik Domanski; Caren C Helbing
Roscovitine inhibits thyroid hormone-induced tail regression of the frog tadpole and reveals a role for cyclin C/Cdk8 in the establishment of the metamorphic gene expression program.
Developmental dynamics : an official publication of the American Association of Anatomists 2008;237(12):3787-97.
2008: Alison A Walzak; Nik Veldhoen; Xiaolan Feng; Karl Riabowol; Caren C Helbing
Expression profiles of mRNA transcript variants encoding the human inhibitor of growth tumor suppressor gene family in normal and neoplastic tissues.
Experimental cell research 2008;314(2):273-85.
2007: Caren C Helbing; Carmen M Bailey; Lan Ji; Mark P Gunderson; Fang Zhang; Nik Veldhoen; Rachel C Skirrow; Ruixia Mu; Mary Lesperance; Gary W Holcombe; Patricia A Kosian; Joseph E Tietge; Joseph J Korte; Sigmund J Degitz
Identification of gene expression indicators for thyroid axis disruption in a Xenopus laevis metamorphosis screening assay. Part 1. Effects on the brain.
Aquatic toxicology (Amsterdam, Netherlands) 2007;82(4):227-41.
2007: Caren C Helbing; Lan Ji; Carmen M Bailey; Nik Veldhoen; Fang Zhang; Gary W Holcombe; Patricia A Kosian; Joseph E Tietge; Joseph J Korte; Sigmund J Degitz
Identification of gene expression indicators for thyroid axis disruption in a Xenopus laevis metamorphosis screening assay. Part 2. Effects on the tail and hindlimb.
Aquatic toxicology (Amsterdam, Netherlands) 2007;82(4):215-26.
2007: Caren C Helbing; Kate Crump; Carmen M Bailey; Satomi Kohno; Nik Veldhoen; Yue Song; Teresa A Bryan; Dieldrich S Bermudez; Juan Ausió; Louis Guillette
Characterization of Inhibitor of Growth 2 tumor suppressor in Alligator mississippiensis, its conservation in Archosauria, and response to thyroid stimulating hormone.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2007;146(2):279-88.
2006: Nik Veldhoen; Rachel C Skirrow; Heather Osachoff; Heidi Wigmore; David J Clapson; Mark P Gunderson; Graham Van Aggelen; Caren C Helbing
The bactericidal agent triclosan modulates thyroid hormone-associated gene expression and disrupts postembryonic anuran development.
Aquatic toxicology (Amsterdam, Netherlands) 2006;80(3):217-27.
2006: Caren C Helbing; Kate Crump; Carmen M Bailey; Satomi Kohno; Nik Veldhoen; Teresa A Bryan; Dieldrich S Bermudez; Louis Guillette
Isolation of the alligator (Alligator mississippiensis) thyroid hormone receptor alpha and beta transcripts and their responsiveness to thyroid stimulating hormone.
General and comparative endocrinology 2006;149(2):141-50.
2006: Maki Tabuchi; Nik Veldhoen; Neil J Dangerfield; Steven J Jeffries; Caren C Helbing; Peter S Ross
PCB-related alteration of thyroid hormones and thyroid hormone receptor gene expression in free-ranging harbor seals (Phoca vitulina).
Environmental health perspectives 2006;114(7):1024-31.
2006: Nik Veldhoen; Ashley Boggs; Katherine Walzak; Caren C Helbing
Exposure to tetrabromobisphenol-A alters TH-associated gene expression and tadpole metamorphosis in the Pacific tree frog Pseudacris regilla.
Aquatic toxicology (Amsterdam, Netherlands) 2006;78(3):292-302.
2006: Nik Veldhoen; Rachel C Skirrow; Lan Ji; Dominik Domanski; E Ryan Bonfield; Carmen M Bailey; Caren C Helbing
Use of heterologous cDNA arrays and organ culture in the detection of thyroid hormone-dependent responses in a sentinel frog, Rana catesbeiana.
Comparative biochemistry and physiology. Part D, Genomics & proteomics 2006;1(2):187-99.
2006: Kathy M Veldhoen; W Ted Allison; Nik Veldhoen; Bradley R Anholt; Caren C Helbing; Craig Hawryshyn
Spatio-temporal characterization of retinal opsin gene expression during thyroid hormone-induced and natural development of rainbow trout.
Visual neuroscience 2006;23(2):169-79.
2006: Fang Zhang; Sigmund J Degitz; Gary W Holcombe; Patricia A Kosian; Joseph E Tietge; Nik Veldhoen; Caren C Helbing
Evaluation of gene expression endpoints in the context of a Xenopus laevis metamorphosis-based bioassay to detect thyroid hormone disruptors.
Aquatic toxicology (Amsterdam, Netherlands) 2006;76(1):24-36.
2004: Christina Fridgen; Michael Berrill; Bruce D Pauli; Caren C Helbing; Kate Werry; Nik Veldhoen
Toxicity of glyphosate-based pesticides to four North American frog species.
Environmental toxicology and chemistry / SETAC 2004;23(8):1928-38.
2003: Caren C Helbing; Kate Werry; Doug Crump; Dominik Domanski; Nik Veldhoen; Carmen M Bailey
Expression profiles of novel thyroid hormone-responsive genes and proteins in the tail of Xenopus laevis tadpoles undergoing precocious metamorphosis.
Molecular endocrinology (Baltimore, Md.) 2003;17(7):1395-409.
2002: Doug Crump; Kate Werry; Nik Veldhoen; Graham Van Aggelen; Caren C Helbing
Exposure to the herbicide acetochlor alters thyroid hormone-dependent gene expression and metamorphosis in Xenopus Laevis.
Environmental health perspectives 2002;110(12):1199-205.
2002: Nik Veldhoen; Doug Crump; Kate Werry; Caren C Helbing
Distinctive gene profiles occur at key points during natural metamorphosis in the Xenopus laevis tadpole tail.
Developmental dynamics : an official publication of the American Association of Anatomists 2002;225(4):457-68.
2001: Nik Veldhoen; Caren C Helbing
Detection of environmental endocrine-disruptor effects on gene expression in live Rana catesbeiana tadpoles using a tail fin biopsy technique.
Environmental toxicology and chemistry / SETAC 2001;20(12):2704-8.