Johannes Veldhuis

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Roelfsema Ferdinand; Pereira Alberto M; Biermasz Nienke R; Frolich Marijke; Keenan Daniel M; Veldhuis Johannes D; Romijn Johannes A
Diminished and irregular TSH secretion with delayed acrophase in patients with Cushing's syndrome.
Keenan Daniel M; Veldhuis Johannes D
Age-dependent regression analysis of male gonadal axis.
Roelfsema Ferdinand; Pereira Alberto M; Veldhuis Johannes D; Adriaanse Ria; Endert Erik; Fliers Eric; Romijn Johannes A
Thyrotropin secretion profiles are not different in men and women.

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All Publications

2009: Roelfsema Ferdinand; Pereira Alberto M; Biermasz Nienke R; Frolich Marijke; Keenan Daniel M; Veldhuis Johannes D; Romijn Johannes A
Diminished and irregular TSH secretion with delayed acrophase in patients with Cushing's syndrome.
European journal of endocrinology / European Federation of Endocrine Societies 2009;161(5):695-703.
2009: Keenan Daniel M; Veldhuis Johannes D
Age-dependent regression analysis of male gonadal axis.
American journal of physiology. Regulatory, integrative and comparative physiology 2009;297(5):R1215-27.
2009: Roelfsema Ferdinand; Pereira Alberto M; Veldhuis Johannes D; Adriaanse Ria; Endert Erik; Fliers Eric; Romijn Johannes A
Thyrotropin secretion profiles are not different in men and women.
The Journal of clinical endocrinology and metabolism 2009;94(10):3964-7.
2009: Veldhuis Johannes D; Roelfsema Ferdinand; Iranmanesh Ali; Carroll Bernard J; Keenan Daniel M; Pincus Steven M
Basal, pulsatile, entropic (patterned), and spiky (staccato-like) properties of ACTH secretion: impact of age, gender, and body mass index.
The Journal of clinical endocrinology and metabolism 2009;94(10):4045-52.
2009: Liu Peter Y; Takahashi Paul Y; Roebuck Pamela D; Bailey Joy N; Keenan Daniel M; Veldhuis Johannes D
Testosterone's short-term positive effect on luteinizing-hormone secretory-burst mass and its negative effect on secretory-burst frequency are attenuated in middle-aged men.
The Journal of clinical endocrinology and metabolism 2009;94(10):3978-86.
2009: Ropelato María Gabriela; Rudaz María Cecilia García; Escobar María Eugenia; Bengolea Sonia Viviana; Calcagno María Luján; Veldhuis Johannes D; Barontini Marta
Acute effects of testosterone infusion on the serum luteinizing hormone profile in eumenorrheic and polycystic ovary syndrome adolescents.
The Journal of clinical endocrinology and metabolism 2009;94(9):3602-10.
2009: Keenan Daniel M; Roelfsema Ferdinand; Carroll Bernard J; Iranmanesh Ali; Veldhuis Johannes D
Sex defines the age dependence of endogenous ACTH-cortisol dose responsiveness.
American journal of physiology. Regulatory, integrative and comparative physiology 2009;297(2):R515-23.
2009: Liu Peter Y; Keenan Daniel M; Kok Petra; Padmanabhan Vasantha; O'Byrne Kevin T; Veldhuis Johannes D
Sensitivity and specificity of pulse detection using a new deconvolution method.
American journal of physiology. Endocrinology and metabolism 2009;297(2):E538-44.
2009: Veldhuis Johannes D; Hudson Susan A; Bailey Joy N; Erickson Dana
Regulation of basal, pulsatile, and entropic (patterned) modes of GH secretion in a putatively low-somatostatin milieu in women.
American journal of physiology. Endocrinology and metabolism 2009;297(2):E483-9.
2009: Veldhuis Johannes D; Hudson Susan B; Erickson Dana; Bailey Joy N; Reynolds George Ann; Bowers Cyril Y
Relative effects of estrogen, age, and visceral fat on pulsatile growth hormone secretion in healthy women.
American journal of physiology. Endocrinology and metabolism 2009;297(2):E367-74.
2009: Veldhuis Johannes D; Keenan Daniel M; Bailey Joy N; Miles John M; Bowers Cyril Y
Preservation of GHRH and GH-releasing peptide-2 efficacy in young men with experimentally induced hypogonadism.
European journal of endocrinology / European Federation of Endocrine Societies 2009;161(2):293-300.
2009: Veldhuis Johannes D; Bowers Cyril Y
Factors other than sex steroids modulate GHRH and GHRP-2 efficacies in men: evaluation using a GnRH agonist/testosterone clamp.
The Journal of clinical endocrinology and metabolism 2009;94(7):2544-50.
2009: Veldhuis Johannes D; Keenan Daniel M; Bailey Joy N; Adeniji Adebordurin M; Miles John M; Bowers Cyril Y
Novel relationships of age, visceral adiposity, insulin-like growth factor (IGF)-I and IGF binding protein concentrations to growth hormone (GH) releasing-hormone and GH releasing-peptide efficacies in men during experimental hypogonadal clamp.
The Journal of clinical endocrinology and metabolism 2009;94(6):2137-43.
2009: Roelfsema Ferdinand; Biermasz Nienke R; Frolich Marijke; Keenan Daniel M; Veldhuis Johannes D; Romijn Johannes A
Diminished and irregular thyrotropin secretion with preserved diurnal rhythm in patients with active acromegaly.
The Journal of clinical endocrinology and metabolism 2009;94(6):1945-50.
2009: Veldhuis Johannes D; Bowers Cyril Y
Determinants of GH-releasing hormone and GH-releasing peptide synergy in men.
American journal of physiology. Endocrinology and metabolism 2009;296(5):E1085-92.
2009: Keenan Daniel M; Alexander Sue; Irvine Clifford; Veldhuis Johannes D
Quantifying nonlinear interactions within the hypothalamo-pituitary-adrenal axis in the conscious horse.
Endocrinology 2009;150(4):1941-51.
2009: Veldhuis Johannes D; Mielke Kristi L; Cosma Mihaela; Soares-Welch Cacia; Paulo Remberto; Miles John M; Bowers Cyril Y
Aromatase and 5alpha-reductase inhibition during an exogenous testosterone clamp unveils selective sex steroid modulation of somatostatin and growth hormone secretagogue actions in healthy older men.
The Journal of clinical endocrinology and metabolism 2009;94(3):973-81.
2009: Veldhuis Johannes D; Keenan Daniel M; Liu Peter Y; Iranmanesh Ali; Takahashi Paul Y; Nehra Ajay X
The aging male hypothalamic-pituitary-gonadal axis: pulsatility and feedback.
Molecular and cellular endocrinology 2009;299(1):14-22.
2009: Veldhuis Johannes D; Keenan Daniel M; Bailey Joy N; Adeniji Adenborduin; Miles John M; Paulo Remberto; Cosma Mihaela; Soares-Welch Cacia
Testosterone supplementation in older men restrains insulin-like growth factor's dose-dependent feedback inhibition of pulsatile growth hormone secretion.
The Journal of clinical endocrinology and metabolism 2009;94(1):246-54.
2009: Roelfsema Ferdinand; Kok Simon; Kok Petra; Pereira Alberto M; Biermasz Nienke R; Smit Jan W; Frolich Marijke; Keenan Daniel M; Veldhuis Johannes D; Romijn Johannes A
Pituitary-hormone secretion by thyrotropinomas.
Pituitary 2009;12(3):200-10.
2008: Veldhuis Johannes D; Keenan Daniel M; Pincus Steven M
Motivations and methods for analyzing pulsatile hormone secretion.
Endocrine reviews 2008;29(7):823-64.
2008: Weltman Arthur; Weltman Judy Y; Watson Winfield Dee Dee; Frick Kirsten; Patrie James; Kok Petra; Keenan Daniel M; Gaesser Glenn A; Veldhuis Johannes D
Effects of continuous versus intermittent exercise, obesity, and gender on growth hormone secretion.
The Journal of clinical endocrinology and metabolism 2008;93(12):4711-20.
2008: Veldhuis Johannes D; Keenan Daniel M; Bailey Joy N; Adeniji Adenborduin; Miles John M; Paulo Remberto; Cosma Mihaela; Soares-Welch Cacia
Estradiol supplementation in postmenopausal women attenuates suppression of pulsatile growth hormone secretion by recombinant human insulin-like growth factor type I.
The Journal of clinical endocrinology and metabolism 2008;93(11):4471-8.
2008: Iranmanesh Ali; Veldhuis Johannes D
Hypocortisolemic clamp unmasks jointly feedforward- and feedback-dependent control of overnight ACTH secretion.
European journal of endocrinology / European Federation of Endocrine Societies 2008;159(5):561-8.
2008: Veldhuis Johannes D; Keenan Daniel M
Secretagogues govern GH secretory-burst waveform and mass in healthy eugonadal and short-term hypogonadal men.
European journal of endocrinology / European Federation of Endocrine Societies 2008;159(5):547-54.
2008: Paulo Remberto C; Brundage Richard; Cosma Mihaela; Mielke Kristi L; Bowers Cyril Y; Veldhuis Johannes D
Estrogen elevates the peak overnight production rate of acylated ghrelin.
The Journal of clinical endocrinology and metabolism 2008;93(11):4440-7.
2008: Roelfsema Ferdinand; Pereira Alberto M; Keenan Daniel M; Veldhuis Johannes D; Romijn Johannes A
Thyrotropin secretion by thyrotropinomas is characterized by increased pulse frequency, delayed diurnal rhythm, enhanced basal secretion, spikiness, and disorderliness.
The Journal of clinical endocrinology and metabolism 2008;93(10):4052-7.
2008: Matveyenko Aleksey V; Veldhuis Johannes D; Butler Peter C
Adaptations in pulsatile insulin secretion, hepatic insulin clearance, and beta-cell mass to age-related insulin resistance in rats.
American journal of physiology. Endocrinology and metabolism 2008;295(4):E832-41.
2008: Kok Petra; Paulo Remberto C; Cosma Mihaela; Mielke Kristi L; Miles John M; Bowers Cyril Y; Veldhuis Johannes D
Estrogen supplementation selectively enhances hypothalamo-pituitary sensitivity to ghrelin in postmenopausal women.
The Journal of clinical endocrinology and metabolism 2008;93(10):4020-6.
2008: Veldhuis Johannes D; Reynolds George Ann; Iranmanesh Ali; Bowers Cyril Y
Twenty-four hour continuous ghrelin infusion augments physiologically pulsatile, nycthemeral, and entropic (feedback-regulated) modes of growth hormone secretion.
The Journal of clinical endocrinology and metabolism 2008;93(9):3597-603.
2008: Matveyenko Aleksey V; Veldhuis Johannes D; Butler Peter C
Measurement of pulsatile insulin secretion in the rat: direct sampling from the hepatic portal vein.
American journal of physiology. Endocrinology and metabolism 2008;295(3):E569-74.
2008: Veldhuis Johannes D
Aging and hormones of the hypothalamo-pituitary axis: gonadotropic axis in men and somatotropic axes in men and women.
Ageing research reviews 2008;7(3):189-208.
2008: Krieg Richard J; Veldhuis Johannes D; Thornhill Barbara A; Chevalier Robert L; Gil Gregorio
Growth hormone (GH) secretion, GH-dependent gene expression, and sexually dimorphic body growth in young rats with chronic renal failure.
Endocrine 2008;33(3):323-30.
2008: Waters Debra L; Qualls Clifford R; Dorin Richard I; Veldhuis Johannes D; Baumgartner Richard N
Altered growth hormone, cortisol, and leptin secretion in healthy elderly persons with sarcopenia and mixed body composition phenotypes.
The journals of gerontology. Series A, Biological sciences and medical sciences 2008;63(5):536-41.
2008: Cosma Mihaela; Bailey Joy; Miles John M; Bowers Cyril Y; Veldhuis Johannes D
Pituitary and/or peripheral estrogen-receptor alpha regulates follicle-stimulating hormone secretion, whereas central estrogenic pathways direct growth hormone and prolactin secretion in postmenopausal women.
The Journal of clinical endocrinology and metabolism 2008;93(3):951-8.
2008: Paulo Remberto C; Cosma Mihaela; Soares-Welch Cacia; Bailey Joy N; Mielke Kristi L; Miles John M; Bowers Cyril Y; Veldhuis Johannes D
Gonadal status and body mass index jointly determine growth hormone (GH)-releasing hormone/GH-releasing peptide synergy in healthy men.
The Journal of clinical endocrinology and metabolism 2008;93(3):944-50.
2008: Natesampillai Sekar; Kerkvliet Jason; Leung Peter C K; Veldhuis Johannes D
Regulation of Kruppel-like factor 4, 9, and 13 genes and the steroidogenic genes LDLR, StAR, and CYP11A in ovarian granulosa cells.
American journal of physiology. Endocrinology and metabolism 2008;294(2):E385-91.
2008: Bowers Cyril Y; Merriam George R; Veldhuis Johannes D
Validation of growth-hormone-releasing peptide 2 for the diagnosis of adult growth hormone deficiency.
Nature clinical practice. Endocrinology & metabolism 2008;4(2):68-9.
2007: Liu Peter Y; Iranmanesh Ali; Keenan Daniel M; Pincus Steven M; Veldhuis Johannes D
A noninvasive measure of negative-feedback strength, approximate entropy, unmasks strong diurnal variations in the regularity of LH secretion.
American journal of physiology. Endocrinology and metabolism 2007;293(5):E1409-15.
2007: Veldhuis Johannes D; Keenan Daniel M; Bowers Cyril Y
Peripheral estrogen receptor-alpha selectively modulates the waveform of GH secretory bursts in healthy women.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;293(4):R1514-21.
2007: Takahashi Paul Y; Votruba Patrick; Abu-Rub Mohammed; Mielke Kristi; Veldhuis Johannes D
Age attenuates testosterone secretion driven by amplitude-varying pulses of recombinant human luteinizing hormone during acute gonadotrope inhibition in healthy men.
The Journal of clinical endocrinology and metabolism 2007;92(9):3626-32.
2007: Iranmanesh Ali; Carpenter Paul C; Mielke Kristi; Bowers Cyril Y; Veldhuis Johannes D
Putative somatostatin suppression potentiates adrenocorticotropin secretion driven by ghrelin and human corticotropin-releasing hormone.
The Journal of clinical endocrinology and metabolism 2007;92(9):3653-9.
2007: Muniyappa Ranganath; Sorkin John D; Veldhuis Johannes D; Harman S Mitchell; Münzer Thomas; Bhasin Shalender; Blackman Marc R
Long-term testosterone supplementation augments overnight growth hormone secretion in healthy older men.
American journal of physiology. Endocrinology and metabolism 2007;293(3):E769-75.
2007: Veldhuis Johannes D; Keenan Daniel M; Bowers Cyril Y
Estimation of the size and shape of GH secretory bursts in healthy women using a physiological estradiol clamp and variable-waveform deconvolution model.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;293(3):R1013-21.
2007: Veldhuis Johannes D; Cosma Mihaela; Erickson Dana; Paulo Remberto; Mielke Kristi; Farhy Leon S; Bowers Cyril Y
Tripartite control of growth hormone secretion in women during controlled estradiol repletion.
The Journal of clinical endocrinology and metabolism 2007;92(6):2336-45.
2007: van der Klaauw A A; Pereira A M; van Thiel S W; Frolich M; Iranmanesh A; Veldhuis J D; Roelfsema F; Romijn J A
Attenuated pulse size, disorderly growth hormone and prolactin secretion with preserved nyctohemeral rhythm distinguish irradiated from surgically treated acromegaly patients.
Clinical endocrinology 2007;66(4):489-98.
2007: Farhy Leon S; Bowers Cyril Y; Veldhuis Johannes D
Model-projected mechanistic bases for sex differences in growth hormone regulation in humans.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;292(4):R1577-93.
2007: Ritzel Robert A; Meier Juris J; Lin Chia-Yu; Veldhuis Johannes D; Butler Peter C
Human islet amyloid polypeptide oligomers disrupt cell coupling, induce apoptosis, and impair insulin secretion in isolated human islets.
Diabetes 2007;56(1):65-71.
2007: Escobar María Eugenia; Ropelato María Gabriela; Ballerini María Gabriela; Gryngarten Mirta Graciela; Rudaz María Cecilia García; Veldhuis Johannes D; Barontini Marta
Acceleration of luteinizing hormone pulse frequency in adolescent girls with a history of central precocious puberty with versus without hyperandrogenism.
Hormone research 2007;68(6):278-85.
2006: Liu Peter Y; Takahashi Paul Y; Roebuck Pamela D; Veldhuis Johannes D
Age or factors associated with aging attenuate testosterone's concentration-dependent enhancement of the regularity of luteinizing hormone secretion in healthy men.
The Journal of clinical endocrinology and metabolism 2006;91(10):4077-84.
2006: Veldhuis Johannes D; Keenan Daniel M; Iranmanesh Ali; Mielke Kristi; Miles John M; Bowers Cyril Y
Estradiol potentiates ghrelin-stimulated pulsatile growth hormone secretion in postmenopausal women.
The Journal of clinical endocrinology and metabolism 2006;91(9):3559-65.
2006: Matveyenko Aleksey V; Veldhuis Johannes D; Butler Peter C
Mechanisms of impaired fasting glucose and glucose intolerance induced by an approximate 50% pancreatectomy.
Diabetes 2006;55(8):2347-56.
2006: Meier Juris J; Hong-McAtee Irene; Galasso Ryan; Veldhuis Johannes D; Moran Antoinette; Hering Bernhard J; Butler Peter C
Intrahepatic transplanted islets in humans secrete insulin in a coordinate pulsatile manner directly into the liver.
Diabetes 2006;55(8):2324-32.
2006: Franco Celina; Veldhuis Johannes D; Iranmanesh Ali; Brandberg John; Lönn Lars; Andersson Björn; Bengtsson Bengt-Ake; Svensson Johan; Johannsson Gudmundur
Thigh intermuscular fat is inversely associated with spontaneous GH release in post-menopausal women with abdominal obesity.
European journal of endocrinology / European Federation of Endocrine Societies 2006;155(2):261-8.
2006: Glintborg Dorte; Hermann Anne Pernille; Andersen Marianne; Hagen Claus; Beck-Nielsen Henning; Veldhuis Johannes D; Henriksen Jan Erik
Effect of pioglitazone on glucose metabolism and luteinizing hormone secretion in women with polycystic ovary syndrome.
Fertility and sterility 2006;86(2):385-97.
2006: Meneilly Graydon S; Veldhuis Johannes D; Elahi Dariush
Pulsatile insulin secretion in elderly patients with diabetes.
Diabetes research and clinical practice 2006;73(2):218-20.
2006: Svensson Johan; Johannsson Gudmundur; Iranmanesh Ali; Albertsson-Wikland Kerstin; Veldhuis Johannes D; Bengtsson Bengt-Ake
GH secretory pattern in young adults who discontinued GH treatment for GH deficiency and decreased longitudinal growth in childhood.
European journal of endocrinology / European Federation of Endocrine Societies 2006;155(1):91-9.
2006: Ulloa-Aguirre Alfredo; Portocarrero Lesly; Zariñán Teresa; Olivares Aleida; Carranza-Lira Sebastián; Veldhuis Johannes D; López-Alvarenga Juan C
Effects of metformin on inappropriate LH release in women with polycystic ovarian syndrome and insulin resistance.
Reproductive biomedicine online 2006;12(6):669-83.
2006: van der Klaauw A A; Pereira A M; van Thiel S W; Smit J W A; Corssmit E P M; Biermasz N R; Frolich M; Iranmanesh A; Veldhuis J D; Roelfsema F; Romijn J A
GH deficiency in patients irradiated for acromegaly: significance of GH stimulatory tests in relation to the 24 h GH secretion.
European journal of endocrinology / European Federation of Endocrine Societies 2006;154(6):851-8.
2006: Mazziotti Gherardo; Cimino Vincenzo; De Menis Ernesto; Bonadonna Stefania; Bugari Giovanna; De Marinis Laura; Veldhuis Johannes D; Giustina Andrea
Active acromegaly enhances spontaneous parathyroid hormone pulsatility.
Metabolism: clinical and experimental 2006;55(6):736-40.
2006: Veldhuis Johannes D; Iranmanesh Ali; Mielke Kristi; Miles John M; Carpenter Paul C; Bowers Cyril Y
Ghrelin potentiates growth hormone secretion driven by putative somatostatin withdrawal and resists inhibition by human corticotropin-releasing hormone.
The Journal of clinical endocrinology and metabolism 2006;91(6):2441-6.
2006: Keenan Daniel M; Takahashi Paul Y; Liu Peter Y; Roebuck Pamela D; Nehra Ajay X; Iranmanesh Ali; Veldhuis Johannes D
An ensemble model of the male gonadal axis: illustrative application in aging men.
Endocrinology 2006;147(6):2817-28.
2006: Young Elizabeth A; Veldhuis Johannes D
Disordered adrenocorticotropin secretion in women with major depression.
The Journal of clinical endocrinology and metabolism 2006;91(5):1924-8.
2006: Weltman Arthur; Weltman Judy Y; Roy Cathy Pritzlaff; Wideman Laurie; Patrie James; Evans William S; Veldhuis Johannes D
Growth hormone response to graded exercise intensities is attenuated and the gender difference abolished in older adults.
Journal of applied physiology (Bethesda, Md. : 1985) 2006;100(5):1623-9.
2006: Meier Juris J; Kjems Lise L; Veldhuis Johannes D; Lefèbvre Pierre; Butler Peter C
Postprandial suppression of glucagon secretion depends on intact pulsatile insulin secretion: further evidence for the intraislet insulin hypothesis.
Diabetes 2006;55(4):1051-6.
2006: Veldhuis Johannes D; Roemmich James N; Richmond Erick J; Bowers Cyril Y
Somatotropic and gonadotropic axes linkages in infancy, childhood, and the puberty-adult transition.
Endocrine reviews 2006;27(2):101-40.
2006: Ritzel R A; Veldhuis J D; Butler P C
The mass, but not the frequency, of insulin secretory bursts in isolated human islets is entrained by oscillatory glucose exposure.
American journal of physiology. Endocrinology and metabolism 2006;290(4):E750-6.
2006: McComb Jacalyn J Robert; Qian Xu-Ping; Veldhuis Johannes D; J McGlone John; Norman Reid L
Neuroendocrine responses to psychological stress in eumenorrheic and oligomenorrheic women.
Stress (Amsterdam, Netherlands) 2006;9(1):41-51.
2006: Ritzel Robert A; Butler Alexandra E; Rizza Robert A; Veldhuis Johannes D; Butler Peter C
Relationship between beta-cell mass and fasting blood glucose concentration in humans.
Diabetes care 2006;29(3):717-8.
2006: Natesampillai Sekar; Fernandez-Zapico Martin E; Urrutia Raul; Veldhuis Johannes D
A novel functional interaction between the Sp1-like protein KLF13 and SREBP-Sp1 activation complex underlies regulation of low density lipoprotein receptor promoter function.
The Journal of biological chemistry 2006;281(6):3040-7.
2006: Liu Peter Y; Pincus Steven M; Takahashi Paul Y; Roebuck Pamela D; Iranmanesh Ali; Keenan Daniel M; Veldhuis Johannes D
Aging attenuates both the regularity and joint synchrony of LH and testosterone secretion in normal men: analyses via a model of graded GnRH receptor blockade.
American journal of physiology. Endocrinology and metabolism 2006;290(1):E34-E41.
2005: Veldhuis Johannes D; Keenan Daniel M; Roelfsema Ferdinand; Iranmanesh Ali
Aging-related adaptations in the corticotropic axis: modulation by gender.
Endocrinology and metabolism clinics of North America 2005;34(4):993-1014, x-xi.
2005: Liu Peter Y; Iranmanesh Ali; Nehra Ajay X; Keenan Daniel M; Veldhuis Johannes D
Mechanisms of hypoandrogenemia in healthy aging men.
Endocrinology and metabolism clinics of North America 2005;34(4):935-55, ix.
2005: Veldhuis Johannes D; Erickson Dana; Iranmanesh Ali; Miles John M; Bowers Cyril Y
Sex-steroid control of the aging somatotropic axis.
Endocrinology and metabolism clinics of North America 2005;34(4):877-93, viii.
2005: Iranmanesh Ali; Veldhuis Johannes D
Utility of ultrasensitive growth hormone assays in assessing aging-related hyposomatotropism.
Endocrinology and metabolism clinics of North America 2005;34(4):853-64, vii-viii.
2005: Veldhuis Johannes D; Patrie James M; Frick Kirsten; Weltman Judith Y; Weltman Arthur L
Administration of recombinant human GHRH-1,44-amide for 3 months reduces abdominal visceral fat mass and increases physical performance measures in postmenopausal women.
European journal of endocrinology / European Federation of Endocrine Societies 2005;153(5):669-77.
2005: Meneilly Graydon S; Veldhuis Johannes D; Elahi Dariush
Deconvolution analysis of rapid insulin pulses before and after six weeks of continuous subcutaneous administration of glucagon-like peptide-1 in elderly patients with type 2 diabetes.
The Journal of clinical endocrinology and metabolism 2005;90(11):6251-6.
2005: Veldhuis Johannes D; Erickson Dana; Mielke Kristi; Farhy Leon S; Keenan Daniel M; Bowers Cyril Y
Distinctive inhibitory mechanisms of age and relative visceral adiposity on growth hormone secretion in pre- and postmenopausal women studied under a hypogonadal clamp.
The Journal of clinical endocrinology and metabolism 2005;90(11):6006-13.
2005: Veldhuis Johannes D; Keenan Daniel M; Mielke Kristi; Miles John M; Bowers Cyril Y
Testosterone supplementation in healthy older men drives GH and IGF-I secretion without potentiating peptidyl secretagogue efficacy.
European journal of endocrinology / European Federation of Endocrine Societies 2005;153(4):577-86.
2005: Hollingdal M; Sturis J; Gall M-A; Damsbo P; Pincus S; Veldhuis J D; Pørksen N; Schmitz O; Juhl C B
Repaglinide treatment amplifies first-phase insulin secretion and high-frequency pulsatile insulin release in Type 2 diabetes.
Diabetic medicine : a journal of the British Diabetic Association 2005;22(10):1408-13.
2005: Roemmich James N; Clark Pamela A; Weltman Arthur; Veldhuis Johannes D; Rogol Alan D
Pubertal alterations in growth and body composition: IX. Altered spontaneous secretion and metabolic clearance of growth hormone in overweight youth.
Metabolism: clinical and experimental 2005;54(10):1374-83.
2005: Glintborg Dorte; Støving René Klinkby; Hagen Claus; Hermann Anne Pernille; Frystyk Jan; Veldhuis Johannes D; Flyvbjerg Allan; Andersen Marianne
Pioglitazone treatment increases spontaneous growth hormone (GH) secretion and stimulated GH levels in polycystic ovary syndrome.
The Journal of clinical endocrinology and metabolism 2005;90(10):5605-12.
2005: Liu Peter Y; Takahashi Paul Y; Roebuck Pamela D; Iranmanesh Ali; Veldhuis Johannes D
Aging in healthy men impairs recombinant human luteinizing hormone (LH)-stimulated testosterone secretion monitored under a two-day intravenous pulsatile LH clamp.
The Journal of clinical endocrinology and metabolism 2005;90(10):5544-50.
2005: Keenan Daniel M; Chattopadhyay Somesh; Veldhuis Johannes D
Composite model of time-varying appearance and disappearance of neurohormone pulse signals in blood.
Journal of theoretical biology 2005;236(3):242-55.
2005: Liu Peter Y; Takahashi Paul Y; Roebuck Pamela D; Iranmanesh Ali; Veldhuis Johannes D
Age-specific changes in the regulation of LH-dependent testosterone secretion: assessing responsiveness to varying endogenous gonadotropin output in normal men.
American journal of physiology. Regulatory, integrative and comparative physiology 2005;289(3):R721-8.
2005: Soares-Welch Cacia; Mielke Kristi L; Bowers Cyril Y; Veldhuis Johannes D
Short-term testosterone supplementation does not activate GH and IGF-I production in postmenopausal women.
Clinical endocrinology 2005;63(1):32-8.
2005: Iranmanesh Ali; Veldhuis Johannes D
Combined inhibition of types I and II 5 alpha-reductase selectively augments the basal (nonpulsatile) mode of testosterone secretion in young men.
The Journal of clinical endocrinology and metabolism 2005;90(7):4232-7.
2005: Veldhuis Johannes D; Iranmanesh Ali; Bowers Cyril Y
Joint mechanisms of impaired growth-hormone pulse renewal in aging men.
The Journal of clinical endocrinology and metabolism 2005;90(7):4177-83.
2005: Liu Peter Y; Pincus Steven M; Keenan Daniel M; Roelfsema Ferdinand; Veldhuis Johannes D
Joint synchrony of reciprocal hormonal signaling in human paradigms of both ACTH excess and cortisol depletion.
American journal of physiology. Endocrinology and metabolism 2005;289(1):E160-5.
2005: Meier Juris J; Veldhuis Johannes D; Butler Peter C
Pulsatile insulin secretion dictates systemic insulin delivery by regulating hepatic insulin extraction in humans.
Diabetes 2005;54(6):1649-56.
2005: Farhy Leon S; Veldhuis Johannes D
Deterministic construct of amplifying actions of ghrelin on pulsatile growth hormone secretion.
American journal of physiology. Regulatory, integrative and comparative physiology 2005;288(6):R1649-63.
2005: Takahashi Paul Y; Liu Peter Y; Roebuck Pamela D; Iranmanesh Ali; Veldhuis Johannes D
Graded inhibition of pulsatile luteinizing hormone secretion by a selective gonadotropin-releasing hormone (GnRH)-receptor antagonist in healthy men: evidence that age attenuates hypothalamic GnRH outflow.
The Journal of clinical endocrinology and metabolism 2005;90(5):2768-74.
2005: Veldhuis Johannes D; Farhy Leon; Weltman Arthur L; Kuipers Jonathan; Weltman Judith; Wideman Laurie
Gender modulates sequential suppression and recovery of pulsatile growth hormone secretion by physiological feedback signals in young adults.
The Journal of clinical endocrinology and metabolism 2005;90(5):2874-81.
2005: Veldhuis Johannes D; Frystyk Jan; Iranmanesh Ali; Ørskov Hans
Testosterone and estradiol regulate free insulin-like growth factor I (IGF-I), IGF binding protein 1 (IGFBP-1), and dimeric IGF-I/IGFBP-1 concentrations.
The Journal of clinical endocrinology and metabolism 2005;90(5):2941-7.
2005: Soares-Welch Cacia; Farhy Leon; Mielke Kristi L; Mahmud Farid H; Miles John M; Bowers Cyril Y; Veldhuis Johannes D
Complementary secretagogue pairs unmask prominent gender-related contrasts in mechanisms of growth hormone pulse renewal in young adults.
The Journal of clinical endocrinology and metabolism 2005;90(4):2225-32.
2005: Liu Peter Y; Hoey Kelley A; Mielke Kristi L; Veldhuis Johannes D; Khosla Sundeep
A randomized placebo-controlled trial of short-term graded transdermal estradiol in healthy gonadotropin-releasing hormone agonist-suppressed pre- and postmenopausal women: effects on serum markers of bone turnover, insulin-like growth factor-I, and osteoclastogenic mediators.
The Journal of clinical endocrinology and metabolism 2005;90(4):1953-60.
2005: Veldhuis Johannes D; Veldhuis Nathan J D; Keenan Daniel M; Iranmanesh Ali
Age diminishes the testicular steroidogenic response to repeated intravenous pulses of recombinant human LH during acute GnRH-receptor blockade in healthy men.
American journal of physiology. Endocrinology and metabolism 2005;288(4):E775-81.
2005: Erickson Dana; Keenan Daniel M; Farhy Leon; Mielke Kristi; Bowers Cyril Y; Veldhuis Johannes D
Determinants of dual secretagogue drive of burst-like growth hormone secretion in premenopausal women studied under a selective estradiol clamp.
The Journal of clinical endocrinology and metabolism 2005;90(3):1741-51.
2005: van Aken M O; Pereira A M; van Thiel S W; van den Berg G; Frölich M; Veldhuis J D; Romijn J A; Roelfsema F
Irregular and frequent cortisol secretory episodes with preserved diurnal rhythmicity in primary adrenal Cushing's syndrome.
The Journal of clinical endocrinology and metabolism 2005;90(3):1570-7.
2005: Veldhuis Johannes D; Anderson Stacey M; Iranmanesh Ali; Bowers Cyril Y
Testosterone blunts feedback inhibition of growth hormone secretion by experimentally elevated insulin-like growth factor-I concentrations.
The Journal of clinical endocrinology and metabolism 2005;90(3):1613-7.
2005: Veldhuis Johannes D; Bae Anthony; Swerdloff Ronald S; Iranmanesh Ali; Wang Christina
Experimentally induced androgen depletion accentuates ethnicity-related contrasts in luteinizing hormone secretion in asian and caucasian men.
The Journal of clinical endocrinology and metabolism 2005;90(3):1632-8.
2005: Bonadonna Stefania; Burattin Anna; Nuzzo Monica; Bugari Giovanna; Rosei Enrico Agabiti; Valle Domenico; Iori Nicoletta; Bilezikian John P; Veldhuis Johannes D; Giustina Andrea
Chronic glucocorticoid treatment alters spontaneous pulsatile parathyroid hormone secretory dynamics in human subjects.
European journal of endocrinology / European Federation of Endocrine Societies 2005;152(2):199-205.
2005: Veldhuis Johannes D; Roemmich James N; Richmond Erick J; Rogol Alan D; Lovejoy Jennifer C; Sheffield-Moore Melinda; Mauras Nelly; Bowers Cyril Y
Endocrine control of body composition in infancy, childhood, and puberty.
Endocrine reviews 2005;26(1):114-46.
2005: Liu Peter Y; Pincus Steven M; Keenan Daniel M; Roelfsema Ferdinand; Veldhuis Johannes D
Analysis of bidirectional pattern synchrony of concentration-secretion pairs: implementation in the human testicular and adrenal axes.
American journal of physiology. Regulatory, integrative and comparative physiology 2005;288(2):R440-6.
2005: Veldhuis Johannes D; Iranmanesh Ali; Mulligan Thomas
Age and testosterone feedback jointly control the dose-dependent actions of gonadotropin-releasing hormone in healthy men.
The Journal of clinical endocrinology and metabolism 2005;90(1):302-9.
2005: Veldhuis Johannes D; Iranmanesh Ali
Short-term aromatase-enzyme blockade unmasks impaired feedback adaptations in luteinizing hormone and testosterone secretion in older men.
The Journal of clinical endocrinology and metabolism 2005;90(1):211-8.
2005: van Aken Maarten O; Pereira Alberto M; Frölich Marijke; Romijn Johannes A; Pijl Hanno; Veldhuis Johannes D; Roelfsema Ferdinand
Growth hormone secretion in primary adrenal Cushing's syndrome is disorderly and inversely correlated with body mass index.
American journal of physiology. Endocrinology and metabolism 2005;288(1):E63-70.
2005: Veldhuis J D; Keenan D M; Iranmanesh A
Mechanisms of ensemble failure of the male gonadal axis in aging.
Journal of endocrinological investigation 2005;28(3 Suppl):8-13.
2004: Veldhuis Johannes D; Patrie James T; Frick Kirsten; Weltman Judith Y; Weltman Arthur
Sustained growth hormone (GH) and insulin-like growth factor I responses to prolonged high-dose twice-daily GH-releasing hormone stimulation in middle-aged and older men.
The Journal of clinical endocrinology and metabolism 2004;89(12):6325-30.
2004: Veldhuis Johannes D; Patrie James T; Brill Kimberly T; Weltman Judith Y; Mueller Eugenio E; Bowers Cyril Y; Weltman Arthur
Contributions of gender and systemic estradiol and testosterone concentrations to maximal secretagogue drive of burst-like growth hormone secretion in healthy middle-aged and older adults.
The Journal of clinical endocrinology and metabolism 2004;89(12):6291-6.
2004: Seals Richard C; Urban Randall J; Sekar Natesampillai; Veldhuis Johannes D
Up-regulation of basal transcriptional activity of the cytochrome P450 cholesterol side-chain cleavage (CYP11A) gene by isoform-specific calcium-calmodulin-dependent protein kinase in primary cultures of ovarian granulosa cells.
Endocrinology 2004;145(12):5616-22.
2004: Veldhuis Johannes D; Iranmanesh Ali; Keenan Daniel M
Erosion of endogenous testosterone-driven negative feedback on pulsatile luteinizing hormone secretion in healthy aging men.
The Journal of clinical endocrinology and metabolism 2004;89(11):5753-61.
2004: Veldhuis Johannes D; Weltman Judith Y; Weltman Arthur L; Iranmanesh Ali; Muller Eugenio E; Bowers Cyril Y
Age and secretagogue type jointly determine dynamic growth hormone responses to exogenous insulin-like growth factor-negative feedback in healthy men.
The Journal of clinical endocrinology and metabolism 2004;89(11):5542-8.
2004: Liu Peter Y; Swerdloff Ronald S; Veldhuis Johannes D
Clinical review 171: The rationale, efficacy and safety of androgen therapy in older men: future research and current practice recommendations.
The Journal of clinical endocrinology and metabolism 2004;89(10):4789-96.
2004: Posener Joel A; Charles DeBattista; Veldhuis Johannes D; Province Michael A; Williams Gordon H; Schatzberg Alan F
Process irregularity of cortisol and adrenocorticotropin secretion in men with major depressive disorder.
Psychoneuroendocrinology 2004;29(9):1129-37.
2004: Keenan Daniel M; Roelfsema Ferdinand; Veldhuis Johannes D
Endogenous ACTH concentration-dependent drive of pulsatile cortisol secretion in the human.
American journal of physiology. Endocrinology and metabolism 2004;287(4):E652-61.
2004: Erickson Dana; Keenan Daniel M; Mielke Kristi; Bradford Kandace; Bowers Cyril Y; Miles John M; Veldhuis Johannes D
Dual secretagogue drive of burst-like growth hormone secretion in postmenopausal compared with premenopausal women studied under an experimental estradiol clamp.
The Journal of clinical endocrinology and metabolism 2004;89(9):4746-54.
2004: Iranmanesh Ali; Bowers Cyril Y; Veldhuis Johannes D
Activation of somatostatin-receptor subtype-2/-5 suppresses the mass, frequency, and irregularity of growth hormone (GH)-releasing peptide-2-stimulated GH secretion in men.
The Journal of clinical endocrinology and metabolism 2004;89(9):4581-7.
2004: Veldhuis Johannes D; Iranmanesh Ali
Pulsatile intravenous infusion of recombinant human luteinizing hormone under acute gonadotropin-releasing hormone receptor blockade reconstitutes testosterone secretion in young men.
The Journal of clinical endocrinology and metabolism 2004;89(9):4474-9.
2004: Irving Brian A; Patrie James T; Anderson Stacey M; Watson-Winfield Deidre D; Frick Kirsten I; Evans William S; Veldhuis Johannes D; Weltman Arthur
The effects of time following acute growth hormone administration on metabolic and power output measures during acute exercise.
The Journal of clinical endocrinology and metabolism 2004;89(9):4298-305.
2004: Sekar Natesampillai; Veldhuis Johannes D
Involvement of Sp1 and SREBP-1a in transcriptional activation of the LDL receptor gene by insulin and LH in cultured porcine granulosa-luteal cells.
American journal of physiology. Endocrinology and metabolism 2004;287(1):E128-35.
2004: van Aken Maarten O; Pereira Alberto M; van den Berg Gerrit; Romijn Johannes A; Veldhuis Johannes D; Roelfsema Ferdinand
Profound amplification of secretory-burst mass and anomalous regularity of ACTH secretory process in patients with Nelson's syndrome compared with Cushing's disease.
Clinical endocrinology 2004;60(6):765-72.
2004: Zhang Gongqiao; Veldhuis Johannes D
Requirement for proximal putative Sp1 and AP-2 cis-deoxyribonucleic acid elements in mediating basal and luteinizing hormone- and insulin-dependent in vitro transcriptional activation of the CYP17 gene in porcine theca cells.
Endocrinology 2004;145(6):2760-6.
2004: Farhy Leon S; Veldhuis Johannes D
Putative GH pulse renewal: periventricular somatostatinergic control of an arcuate-nuclear somatostatin and GH-releasing hormone oscillator.
American journal of physiology. Regulatory, integrative and comparative physiology 2004;286(6):R1030-42.
2004: Zhang Gongqiao; Veldhuis Johannes D
Insulin drives transcriptional activity of the CYP17 gene in primary cultures of swine theca cells.
Biology of reproduction 2004;70(6):1600-5.
2004: McCartney Christopher R; Bellows Amy B; Gingrich Melissa B; Hu Yun; Evans William S; Marshall John C; Veldhuis Johannes D
Exaggerated 17-hydroxyprogesterone response to intravenous infusions of recombinant human LH in women with polycystic ovary syndrome.
American journal of physiology. Endocrinology and metabolism 2004;286(6):E902-8.
2004: Bowers Cyril Y; Granda Ramona; Mohan Subburaman; Kuipers Jonathan; Baylink David; Veldhuis Johannes D
Sustained elevation of pulsatile growth hormone (GH) secretion and insulin-like growth factor I (IGF-I), IGF-binding protein-3 (IGFBP-3), and IGFBP-5 concentrations during 30-day continuous subcutaneous infusion of GH-releasing peptide-2 in older men and women.
The Journal of clinical endocrinology and metabolism 2004;89(5):2290-300.
2004: Keenan Daniel M; Alexander Susan; Irvine Clifford H G; Clarke Iain; Scott Chris; Turner Anne; Tilbrook A J; Canny B J; Veldhuis Johannes D
Reconstruction of in vivo time-evolving neuroendocrine dose-response properties unveils admixed deterministic and stochastic elements.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(17):6740-5.
2004: van Dam Eveline W C M; Roelfsema Ferdinand; Veldhuis Johannes D; Hogendoorn Simone; Westenberg Jos; Helmerhorst Frans M; Frölich Marijke; Krans H Michiel J; Meinders A Edo; Pijl Hanno
Retention of estradiol negative feedback relationship to LH predicts ovulation in response to caloric restriction and weight loss in obese patients with polycystic ovary syndrome.
American journal of physiology. Endocrinology and metabolism 2004;286(4):E615-20.
2004: Licinio Julio; Caglayan Sinan; Ozata Metin; Yildiz Bulent O; de Miranda Patricia B; O'Kirwan Fiona; Whitby Robert; Liang Liyin; Cohen Pinchas; Bhasin Shalender; Krauss Ronald M; Veldhuis Johannes D; Wagner Anthony J; DePaoli Alex M; McCann Samuel M; Wong Ma-Li
Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(13):4531-6.
2004: Veldhuis Johannes D; Anderson Stacey M; Kok Petra; Iranmanesh Ali; Frystyk Jan; Ørskov Hans; Keenan Daniel M
Estradiol supplementation modulates growth hormone (GH) secretory-burst waveform and recombinant human insulin-like growth factor-I-enforced suppression of endogenously driven GH release in postmenopausal women.
The Journal of clinical endocrinology and metabolism 2004;89(3):1312-8.
2004: Veldhuis Johannes D; Evans William S; Iranmanesh Ali; Weltman Arthur L; Bowers Cyril Y
Short-term testosterone supplementation relieves growth hormone autonegative feedback in men.
The Journal of clinical endocrinology and metabolism 2004;89(3):1285-90.
2004: Veldhuis Johannes D; Patrie James; Wideman Laurie; Patterson Mark; Weltman Judy Y; Weltman Arthur
Contrasting negative-feedback control of endogenously driven and exercise-stimulated pulsatile growth hormone secretion in women and men.
The Journal of clinical endocrinology and metabolism 2004;89(2):840-6.
2004: Ritzel Robert A; Hansen John B; Veldhuis Johannes D; Butler Peter C
Induction of beta-cell rest by a Kir6.2/SUR1-selective K(ATP)-channel opener preserves beta-cell insulin stores and insulin secretion in human islets cultured at high (11 mM) glucose.
The Journal of clinical endocrinology and metabolism 2004;89(2):795-805.
2004: Keenan Daniel M; Veldhuis Johannes D
Divergent gonadotropin-gonadal dose-responsive coupling in healthy young and aging men.
American journal of physiology. Regulatory, integrative and comparative physiology 2004;286(2):R381-9.
2004: Østergård Torben; Degn Kristine B; Gall Mari-Anne; Carr Richard D; Veldhuis Johannes D; Thomsen Mads K; Rizza Robert A; Schmitz Ole
The insulin secretagogues glibenclamide and repaglinide do not influence growth hormone secretion in humans but stimulate glucagon secretion during profound insulin deficiency.
The Journal of clinical endocrinology and metabolism 2004;89(1):297-302.
2004: Veldhuis Johannes D; Anderson Stacey M; Patrie James T; Bowers Cyril Y
Estradiol supplementation in postmenopausal women doubles rebound-like release of growth hormone (GH) triggered by sequential infusion and withdrawal of somatostatin: evidence that estrogen facilitates endogenous GH-releasing hormone drive.
The Journal of clinical endocrinology and metabolism 2004;89(1):121-7.
2004: Weekers Frank; Michalaki Marina; Coopmans Willy; Van Herck Eric; Veldhuis Johannes D; Darras Veerle M; Van den Berghe Greet
Endocrine and metabolic effects of growth hormone (GH) compared with GH-releasing peptide, thyrotropin-releasing hormone, and insulin infusion in a rabbit model of prolonged critical illness.
Endocrinology 2004;145(1):205-13.
2004: Biermasz Nienke R; Pereira Alberto M; Frölich Marijke; Romijn Johannes A; Veldhuis Johannes D; Roelfsema Ferdinand
Octreotide represses secretory-burst mass and nonpulsatile secretion but does not restore event frequency or orderly GH secretion in acromegaly.
American journal of physiology. Endocrinology and metabolism 2004;286(1):E25-30.
2004: Johnson Michael L; Virostko Amelia; Veldhuis Johannes D; Evans William S
Deconvolution analysis as a hormone pulse-detection algorithm.
Methods in enzymology 2004;384():40-54.
2003: Schmitt Claus P; Obry Jennifer; Feneberg Reinhard; Veldhuis Johannes D; Mehls Otto; Ritz Eberhard; Schaefer Franz
Beta1-adrenergic blockade augments pulsatile PTH secretion in humans.
Journal of the American Society of Nephrology : JASN 2003;14(12):3245-50.
2003: Veldhuis Johannes D; Evans William S; Bowers Cyril Y
Estradiol supplementation enhances submaximal feed-forward drive of growth hormone (GH) secretion by recombinant human GH-releasing hormone-1,44-amide in a putatively somatostatin-withdrawn milieu.
The Journal of clinical endocrinology and metabolism 2003;88(11):5484-9.
2003: Keenan Daniel M; Evans William S; Veldhuis Johannes D
Control of LH secretory-burst frequency and interpulse-interval regularity in women.
American journal of physiology. Endocrinology and metabolism 2003;285(5):E938-48.
2003: Farhy Leon S; Veldhuis Johannes D
Joint pituitary-hypothalamic and intrahypothalamic autofeedback construct of pulsatile growth hormone secretion.
American journal of physiology. Regulatory, integrative and comparative physiology 2003;285(5):R1240-9.
2003: Keenan Daniel M; Veldhuis Johannes D
Cortisol feedback state governs adrenocorticotropin secretory-burst shape, frequency, and mass in a dual-waveform construct: time of day-dependent regulation.
American journal of physiology. Regulatory, integrative and comparative physiology 2003;285(5):R950-61.
2003: Veldhuis Johannes D; Bowers Cyril Y
Sex-steroid modulation of growth hormone (GH) secretory control: three-peptide ensemble regulation under dual feedback restraint by GH and IGF-I.
Endocrine 2003;22(1):25-40.
2003: Gianotti L; Veldhuis J D; Destefanis S; Lanfranco F; Ramunni J; Arvat E; Marzetto M; Boutignon F; Deghenghi R; Ghigo E
Suppression and recovery of LH secretion by a potent and selective GnRH-receptor antagonist peptide in healthy early follicular-phase women are mediated via selective control of LH secretory burst mass.
Clinical endocrinology 2003;59(4):526-32.
2003: Weltman A; Wideman L; Weltman J Y; Veldhuis J D
Neuroendocrine control of GH release during acute aerobic exercise.
Journal of endocrinological investigation 2003;26(9):843-50.
2003: Veldhuis J D; Bowers C Y
Human GH pulsatility: an ensemble property regulated by age and gender.
Journal of endocrinological investigation 2003;26(9):799-813.
2003: Keenan Daniel M; Roelfsema Ferdinand; Biermasz Nienke; Veldhuis Johannes D
Physiological control of pituitary hormone secretory-burst mass, frequency, and waveform: a statistical formulation and analysis.
American journal of physiology. Regulatory, integrative and comparative physiology 2003;285(3):R664-73.
2003: Song Soon H; Rhodes Christopher J; Veldhuis Johannes D; Butler Peter C
Diazoxide attenuates glucose-induced defects in first-phase insulin release and pulsatile insulin secretion in human islets.
Endocrinology 2003;144(8):3399-405.
2003: Feneberg Reinhard; Schaefer Franz; Veldhuis Johannes D
Neuroendocrine adaptations in renal disease.
Pediatric nephrology (Berlin, Germany) 2003;18(6):492-7.
2003: Veldhuis Johannes D
Neuroendocrine facets of human puberty.
Neurobiology of aging 2003;24 Suppl 1():S93-S119; discussion S121-2.
2003: Veldhuis Johannes D; Bowers Cyril Y
Three-peptide control of pulsatile and entropic feedback-sensitive modes of growth hormone secretion: modulation by estrogen and aromatizable androgen.
Journal of pediatric endocrinology & metabolism : JPEM 2003;16 Suppl 3():587-605.
2003: Chan Jean L; Heist Kathleen; DePaoli Alex M; Veldhuis Johannes D; Mantzoros Christos S
The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men.
The Journal of clinical investigation 2003;111(9):1409-21.
2003: Rogol Alan D; Blethen Sandra L; Sy Judy P; Veldhuis Johannes D
Do growth hormone (GH) serial sampling, insulin-like growth factor-I (IGF-I) or auxological measurements have an advantage over GH stimulation testing in predicting the linear growth response to GH therapy?
Clinical endocrinology 2003;58(2):229-37.
2003: Ritzel Robert A; Veldhuis Johannes D; Butler Peter C
Glucose stimulates pulsatile insulin secretion from human pancreatic islets by increasing secretory burst mass: dose-response relationships.
The Journal of clinical endocrinology and metabolism 2003;88(2):742-7.
2003: Schmitt Claus P; Löcken Swee; Mehls Otto; Veldhuis Johannes D; Lehnert Thomas; Ritz Eberhard; Schaefer Franz
PTH pulsatility but not calcium sensitivity is restored after total parathyroidectomy with heterotopic autotransplantation.
Journal of the American Society of Nephrology : JASN 2003;14(2):407-14.
2003: Veldhuis J D; Pincus S M; Keenan D M
Noninvasive in vivo investigative probes of adaptive mechanisms of neuroendocrine regulation: the paradigm of the hypothalamo-pituitary-gonadal axis in the aging male.
Journal of endocrinological investigation 2003;26(7 Suppl):2-14.
2003: Veldhuis Johannes D
A tripeptidyl ensemble perspective of interactive control of growth hormone secretion.
Hormone research 2003;60(Suppl 1):86-101.
2002: Veldhuis J D; Bidlingmaier M; Anderson S M; Evans W S; Wu Z; Strasburger C J
Impact of experimental blockade of peripheral growth hormone (GH) receptors on the kinetics of endogenous and exogenous GH removal in healthy women and men.
The Journal of clinical endocrinology and metabolism 2002;87(12):5737-45.
2002: Brill Kimberly T; Weltman Arthur L; Gentili Angela; Patrie James T; Fryburg David A; Hanks John B; Urban Randall J; Veldhuis Johannes D
Single and combined effects of growth hormone and testosterone administration on measures of body composition, physical performance, mood, sexual function, bone turnover, and muscle gene expression in healthy older men.
The Journal of clinical endocrinology and metabolism 2002;87(12):5649-57.
2002: López-Alvarenga Juan Carlos; Zariñán Teresa; Olivares Aleida; González-Barranco Jorge; Veldhuis Johannes D; Ulloa-Aguirre Alfredo
Poorly controlled type I diabetes mellitus in young men selectively suppresses luteinizing hormone secretory burst mass.
The Journal of clinical endocrinology and metabolism 2002;87(12):5507-15.
2002: Salvatori Roberto; Fan Xiaoguang; Veldhuis Johannes D; Couch Robert
Serum GH response to pharmacological stimuli and physical exercise in two siblings with two new inactivating mutations in the GH-releasing hormone receptor gene.
European journal of endocrinology / European Federation of Endocrine Societies 2002;147(5):591-6.
2002: Rall Laura C; Walsmith Joseph M; Snydman Laura; Reichlin Seymour; Veldhuis Johannes D; Kehayias Joseph J; Abad Leslie W; Lundgren Nancy T; Roubenoff Ronenn
Cachexia in rheumatoid arthritis is not explained by decreased growth hormone secretion.
Arthritis and rheumatism 2002;46(10):2574-7.
2002: Earnhardt Richard C; Veldhuis Johannes D; Cornett Greg; Hanks John B
Pathophysiology of hyperinsulinemia following pancreas transplantation: altered pulsatile versus Basal insulin secretion and the role of specific transplant anatomy in dogs.
Annals of surgery 2002;236(4):480-90; discussion 490-1.
2002: Leung Kin-Chuen; Howe Chris; Gui Lily Y-Y; Trout Graham; Veldhuis Johannes D; Ho Ken K Y
Physiological and pharmacological regulation of 20-kDa growth hormone.
American journal of physiology. Endocrinology and metabolism 2002;283(4):E836-43.
2002: Van Dam Eveline W C M; Roelfsema Ferdinand; Helmerhorst Frans H; Frölich Marijke; Meinders A Edo; Veldhuis Johannes D; Pijl Hanno
Low amplitude and disorderly spontaneous growth hormone release in obese women with or without polycystic ovary syndrome.
The Journal of clinical endocrinology and metabolism 2002;87(9):4225-30.
2002: Krieg Richard J; Chan Winnie; Lin Kwei-Chi; Kuemmerle Nancy B; Veldhuis Johannes D; Chan James C M
Growth hormone and growth hormone-related mRNA in uremic rats: effect of a growth hormone secretagogue.
Pediatric nephrology (Berlin, Germany) 2002;17(8):585-90.
2002: Richmond E; Rogol A D; Basdemir D; Veldhuis O L; Clarke W; Bowers C Y; Veldhuis J D
Accelerated escape from GH autonegative feedback in midpuberty in males: evidence for time-delimited GH-induced somatostatinergic outflow in adolescent boys.
The Journal of clinical endocrinology and metabolism 2002;87(8):3837-44.
2002: Garcia-Rudaz Maria C; Ropelato Maria G; Escobar Maria E; Veldhuis Johannes D; Barontini Marta
Amplified and orderly growth hormone secretion characterizes lean adolescents with polycystic ovary syndrome.
European journal of endocrinology / European Federation of Endocrine Societies 2002;147(2):207-16.
2002: Young I Ross; Chan E Cheng; Smith Roger; Chrousos George P; Veldhuis Johannes D; Canny Benedict J
Effect of antalarmin, a novel corticotropin-releasing hormone antagonist, on the dynamic function of the preterm ovine fetal hypothalamo-pituitary-adrenal axis.
Neuroendocrinology 2002;76(1):47-54.
2002: Moulas Anargyros N; Krieg Richard J; Veldhuis Johannes D; Chan James C M
Effect of the GH secretagogue L-163,255 and restricted feeding time on GH pulsatility in the rat.
European journal of endocrinology / European Federation of Endocrine Societies 2002;147(1):143-8.
2002: Svensson Johan; Veldhuis Johannes D; Iranmanesh Ali; Bengtsson Bengt-Ake; Johannsson Gudmundur
Increased orderliness of growth hormone (GH) secretion in GH-deficient adults with low serum insulin-like growth factor I.
The Journal of clinical endocrinology and metabolism 2002;87(6):2863-9.
2002: Quigg Mark; Kiely James M; Shneker Bassel; Veldhuis Johannes D; Bertram Edward H
Interictal and postictal alterations of pulsatile secretions of luteinizing hormone in temporal lobe epilepsy in men.
Annals of neurology 2002;51(5):559-66.
2002: Van den Berghe Greet; Baxter Robert C; Weekers Frank; Wouters Pieter; Bowers Cyril Y; Iranmanesh Ali; Veldhuis Johannes D; Bouillon Roger
The combined administration of GH-releasing peptide-2 (GHRP-2), TRH and GnRH to men with prolonged critical illness evokes superior endocrine and metabolic effects compared to treatment with GHRP-2 alone.
Clinical endocrinology 2002;56(5):655-69.
2002: Feneberg Reinhard; Sparber Monika; Veldhuis Johannes D; Mehls Otto; Ritz Eberhard; Schaefer Franz
Altered temporal organization of plasma insulin oscillations in chronic renal failure.
The Journal of clinical endocrinology and metabolism 2002;87(5):1965-73.
2002: Pritzlaff-Roy Cathy J; Widemen Laurie; Weltman Judy Y; Abbott Rob; Gutgesell Margaret; Hartman Mark L; Veldhuis Johannes D; Weltman Arthur
Gender governs the relationship between exercise intensity and growth hormone release in young adults.
Journal of applied physiology (Bethesda, Md. : 1985) 2002;92(5):2053-60.
2002: Van Dam Eveline W C M; Roelfsema Ferdinand; Veldhuis Johannes D; Helmerhorst Frans M; Frölich Marijke; Meinders A Edo; Krans H Michiel J; Pijl Hanno
Increase in daily LH secretion in response to short-term calorie restriction in obese women with PCOS.
American journal of physiology. Endocrinology and metabolism 2002;282(4):E865-72.
2002: Veldhuis Johannes D; Zhang George; Garmey James C
Troglitazone, an insulin-sensitizing thiazolidinedione, represses combined stimulation by LH and insulin of de novo androgen biosynthesis by thecal cells in vitro.
The Journal of clinical endocrinology and metabolism 2002;87(3):1129-33.
2002: Maccario Mauro; Veldhuis Johannes D; Broglio Fabio; Vito Lidia Di; Arvat Emanuela; Deghenghi Romano; Ghigo Ezio
Impact of two or three daily subcutaneous injections of hexarelin, a synthetic growth hormone (GH) secretagogue, on 24-h GH, prolactin, adrenocorticotropin and cortisol secretion in humans.
European journal of endocrinology / European Federation of Endocrine Societies 2002;146(3):310-8.
2002: Weekers Frank; Van Herck Erik; Coopmans Willy; Michalaki Marina; Bowers Cyril Y; Veldhuis Johannes D; Van den Berghe Greet
A novel in vivo rabbit model of hypercatabolic critical illness reveals a biphasic neuroendocrine stress response.
Endocrinology 2002;143(3):764-74.
2002: Farhy Leon S; Straume Martin; Johnson Michael L; Kovatchev Boris; Veldhuis Johannes D
Unequal autonegative feedback by GH models the sexual dimorphism in GH secretory dynamics.
American journal of physiology. Regulatory, integrative and comparative physiology 2002;282(3):R753-64.
2002: Pørksen Niels; Grøfte Thorbjørn; Greisen Jacob; Mengel Anette; Juhl Claus; Veldhuis Johannes D; Schmitz Ole; Rössle Martin; Vilstrup Hendrik
Human insulin release processes measured by intraportal sampling.
American journal of physiology. Endocrinology and metabolism 2002;282(3):E695-702.
2002: Veldhuis Johannes D; Fletcher Terry P; Gatford Kathryn L; Egan Adrian R; Clarke Iain J
Hypophyseal-portal somatostatin (SRIH) and jugular venous growth hormone secretion in the conscious unrestrained ewe.
Neuroendocrinology 2002;75(2):83-91.
2002: Veldhuis J D; Evans W S; Bowers C Y
Impact of estradiol supplementation on dual peptidyl drive of GH secretion in postmenopausal women.
The Journal of clinical endocrinology and metabolism 2002;87(2):859-66.
2002: Gentili A; Mulligan T; Godschalk M; Clore J; Patrie J; Iranmanesh A; Veldhuis J D
Unequal impact of short-term testosterone repletion on the somatotropic axis of young and older men.
The Journal of clinical endocrinology and metabolism 2002;87(2):825-34.
2002: Juhl Claus; Grøfte Thorbjørn; Butler Peter C; Veldhuis Johannes D; Schmitz Ole; Pørksen Niels
Effects of fasting on physiologically pulsatile insulin release in healthy humans.
Diabetes 2002;51 Suppl 1():S255-7.
2002: Pørksen Niels; Hollingdal Malene; Juhl Claus; Butler Peter; Veldhuis Johannes D; Schmitz Ole
Pulsatile insulin secretion: detection, regulation, and role in diabetes.
Diabetes 2002;51 Suppl 1():S245-54.
2002: Lado-Abeal Joaquin; Veldhuis Johannes D; Norman Reid L
Glucose relays information regarding nutritional status to the neural circuits that control the somatotropic, corticotropic, and gonadotropic axes in adult male rhesus macaques.
Endocrinology 2002;143(2):403-10.
2002: Roelfsema Ferdinand; Biermasz Nienke R; Veldhuis Johannes D
Pulsatile, nyctohemeral and entropic characteristics of GH secretion in adult GH-deficient patients: selectively decreased pulsatile release and increased secretory disorderliness with preservation of diurnal timing and gender distinctions.
Clinical endocrinology 2002;56(1):79-87.
2002: Hollingdal M; Juhl C B; Dall R; Sturis J; Veldhuis J D; Schmitz O; Pørksen N
Glucocorticoid induced insulin resistance impairs basal but not glucose entrained high-frequency insulin pulsatility in humans.
Diabetologia 2002;45(1):49-55.
2002: Song Soon H; Kjems Lise; Ritzel Robert; McIntyre Susan M; Johnson Michael L; Veldhuis Johannes D; Butler Peter C
Pulsatile insulin secretion by human pancreatic islets.
The Journal of clinical endocrinology and metabolism 2002;87(1):213-21.
2002: Schoppee Pamela D; Garmey James C; Veldhuis Johannes D
Putative activation of the peroxisome proliferator-activated receptor gamma impairs androgen and enhances progesterone biosynthesis in primary cultures of porcine theca cells.
Biology of reproduction 2002;66(1):190-8.
2002: Wideman Laurie; Weltman Judy Y; Hartman Mark L; Veldhuis Johannes D; Weltman Arthur
Growth hormone release during acute and chronic aerobic and resistance exercise: recent findings.
Sports medicine (Auckland, N.Z.) 2002;32(15):987-1004.
2002: Veldhuis J D; Iranmanesh A; Mulligan T; Bowers C Y
Mechanisms of conjoint failure of the somatotropic and gonadal axes in ageing men.
Novartis Foundation symposium 2002;242():98-118; discussion 118-24.
2001: Anderson S M; Wideman L; Patrie J T; Weltman A; Bowers C Y; Veldhuis J D
E2 supplementation selectively relieves GH's autonegative feedback on GH-releasing peptide-2-stimulated GH secretion.
The Journal of clinical endocrinology and metabolism 2001;86(12):5904-11.
2001: Veldhuis J D; Johnson M L; Veldhuis O L; Straume M; Pincus S M
Impact of pulsatility on the ensemble orderliness (approximate entropy) of neurohormone secretion.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;281(6):R1975-85.
2001: Keenan D M; Veldhuis J D
Disruption of the hypothalamic luteinizing hormone pulsing mechanism in aging men.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;281(6):R1917-24.
2001: Barontini M; García-Rudaz M C; Veldhuis J D
Mechanisms of hypothalamic-pituitary-gonadal disruption in polycystic ovarian syndrome.
Archives of medical research 2001;32(6):544-52.
2001: Veldhuis J D; Iranmanesh A; Naftolowitz D; Tatham N; Cassidy F; Carroll B J
Corticotropin secretory dynamics in humans under low glucocorticoid feedback.
The Journal of clinical endocrinology and metabolism 2001;86(11):5554-63.
2001: Pijl H; Langendonk J G; Burggraaf J; Frölich M; Cohen A F; Veldhuis J D; Meinders A E
Altered neuroregulation of GH secretion in viscerally obese premenopausal women.
The Journal of clinical endocrinology and metabolism 2001;86(11):5509-15.
2001: Weltman A; Weltman J Y; Veldhuis J D; Hartman M L
Body composition, physical exercise, growth hormone and obesity.
Eating and weight disorders : EWD 2001;6(3 Suppl):28-37.
2001: Kjems L L; Kirby B M; Welsh E M; Veldhuis J D; Straume M; McIntyre S S; Yang D; Lefèbvre P; Butler P C
Decrease in beta-cell mass leads to impaired pulsatile insulin secretion, reduced postprandial hepatic insulin clearance, and relative hyperglucagonemia in the minipig.
Diabetes 2001;50(9):2001-12.
2001: Veldhuis J D; Pincus S M; Garcia-Rudaz M C; Ropelato M G; Escobar M E; Barontini M
Disruption of the synchronous secretion of leptin, LH, and ovarian androgens in nonobese adolescents with the polycystic ovarian syndrome.
The Journal of clinical endocrinology and metabolism 2001;86(8):3772-8.
2001: Juhl C B; Pørksen N; Pincus S M; Hansen A P; Veldhuis J D; Schmitz O
Acute and short-term administration of a sulfonylurea (gliclazide) increases pulsatile insulin secretion in type 2 diabetes.
Diabetes 2001;50(8):1778-84.
2001: Veldhuis J D; Bidlingmaier M; Anderson S M; Wu Z; Strasburger C J
Lowering total plasma insulin-like growth factor I concentrations by way of a novel, potent, and selective growth hormone (GH) receptor antagonist, pegvisomant (B2036-peg), augments the amplitude of GH secretory bursts and elevates basal/nonpulsatile GH release in healthy women and men.
The Journal of clinical endocrinology and metabolism 2001;86(7):3304-10.
2001: Mantzoros C S; Ozata M; Negrao A B; Suchard M A; Ziotopoulou M; Caglayan S; Elashoff R M; Cogswell R J; Negro P; Liberty V; Wong M L; Veldhuis J; Ozdemir I C; Gold P W; Flier J S; Licinio J
Synchronicity of frequently sampled thyrotropin (TSH) and leptin concentrations in healthy adults and leptin-deficient subjects: evidence for possible partial TSH regulation by leptin in humans.
The Journal of clinical endocrinology and metabolism 2001;86(7):3284-91.
2001: van den Berghe G; Weekers F; Baxter R C; Wouters P; Iranmanesh A; Bouillon R; Veldhuis J D
Five-day pulsatile gonadotropin-releasing hormone administration unveils combined hypothalamic-pituitary-gonadal defects underlying profound hypoandrogenism in men with prolonged critical illness.
The Journal of clinical endocrinology and metabolism 2001;86(7):3217-26.
2001: Bray M J; Vick T M; Shah N; Anderson S M; Rice L W; Iranmanesh A; Evans W S; Veldhuis J D
Short-term estradiol replacement in postmenopausal women selectively mutes somatostatin's dose-dependent inhibition of fasting growth hormone secretion.
The Journal of clinical endocrinology and metabolism 2001;86(7):3143-9.
2001: Sekar N; Veldhuis J D
Concerted transcriptional activation of the low density lipoprotein receptor gene by insulin and luteinizing hormone in cultured porcine granulosa-luteal cells: possible convergence of protein kinase a, phosphatidylinositol 3-kinase, and mitogen-activated protein kinase signaling pathways.
Endocrinology 2001;142(7):2921-8.
2001: Farhy L S; Straume M; Johnson M L; Kovatchev B; Veldhuis J D
A construct of interactive feedback control of the GH axis in the male.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;281(1):R38-51.
2001: Veldhuis J D; Anderson S M; Shah N; Bray M; Vick T; Gentili A; Mulligan T; Johnson M L; Weltman A; Evans W S; Iranmanesh A
Neurophysiological regulation and target-tissue impact of the pulsatile mode of growth hormone secretion in the human.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2001;11 Suppl A():S25-37.
2001: Schnorr J A; Bray M J; Veldhuis J D
Aromatization mediates testosterone's short-term feedback restraint of 24-hour endogenously driven and acute exogenous gonadotropin-releasing hormone-stimulated luteinizing hormone and follicle-stimulating hormone secretion in young men.
The Journal of clinical endocrinology and metabolism 2001;86(6):2600-6.
2001: Roelfsema F; Biermasz N R; Veldman R G; Veldhuis J D; Frölich M; Stokvis-Brantsma W H; Wit J M
Growth hormone (GH) secretion in patients with an inactivating defect of the GH-releasing hormone (GHRH) receptor is pulsatile: evidence for a role for non-GHRH inputs into the generation of GH pulses.
The Journal of clinical endocrinology and metabolism 2001;86(6):2459-64.
2001: Bergendah M; Veldhuis J D
Is there a physiological role for gonadotrophin oligosaccharide heterogeneity in humans? III. Luteinizing hormone heterogeneity: a medical physiologist's perspective.
Human reproduction (Oxford, England) 2001;16(6):1058-64.
2001: Keenan D M; Veldhuis J D
Hypothesis testing of the aging male gonadal axis via a biomathematical construct.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;280(6):R1755-71.
2001: Veldman R G; Frölich M; Pincus S M; Veldhuis J D; Roelfsema F
Basal, pulsatile, entropic, and 24-hour rhythmic features of secondary hyperprolactinemia due to functional pituitary stalk disconnection mimic tumoral (primary) hyperprolactinemia.
The Journal of clinical endocrinology and metabolism 2001;86(4):1562-7.
2001: Gusenoff J A; Harman S M; Veldhuis J D; Jayme J J; St Clair C; Münzer T; Christmas C; O'Connor K G; Stevens T E; Bellantoni M F; Pabst K; Blackman M R
Cortisol and GH secretory dynamics, and their interrelationships, in healthy aged women and men.
American journal of physiology. Endocrinology and metabolism 2001;280(4):E616-25.
2001: Keenan D M; Licinio J; Veldhuis J D
A feedback-controlled ensemble model of the stress-responsive hypothalamo-pituitary-adrenal axis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(7):4028-33.
2001: Waters D L; Qualls C R; Dorin R; Veldhuis J D; Baumgartner R N
Increased pulsatility, process irregularity, and nocturnal trough concentrations of growth hormone in amenorrheic compared to eumenorrheic athletes.
The Journal of clinical endocrinology and metabolism 2001;86(3):1013-9.
2001: Veldhuis J D; Straume M; Iranmanesh A; Mulligan T; Jaffe C; Barkan A; Johnson M L; Pincus S
Secretory process regularity monitors neuroendocrine feedback and feedforward signaling strength in humans.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;280(3):R721-9.
2001: Veldhuis J D; Evans W S; Bowers C Y; Anderson S
Interactive regulation of postmenopausal growth hormone insulin-like growth factor axis by estrogen and growth hormone-releasing peptide-2.
Endocrine 2001;14(1):45-62.
2001: Evans W S; Anderson S M; Hull L T; Azimi P P; Bowers C Y; Veldhuis J D
Continuous 24-hour intravenous infusion of recombinant human growth hormone (GH)-releasing hormone-(1-44)-amide augments pulsatile, entropic, and daily rhythmic GH secretion in postmenopausal women equally in the estrogen-withdrawn and estrogen-supplemented states.
The Journal of clinical endocrinology and metabolism 2001;86(2):700-12.
2001: Anderson S M; Shah N; Evans W S; Patrie J T; Bowers C Y; Veldhuis J D
Short-term estradiol supplementation augments growth hormone (GH) secretory responsiveness to dose-varying GH-releasing peptide infusions in healthy postmenopausal women.
The Journal of clinical endocrinology and metabolism 2001;86(2):551-60.
2001: Veldhuis J D; Zwart A; Mulligan T; Iranmanesh A
Muting of androgen negative feedback unveils impoverished gonadotropin-releasing hormone/luteinizing hormone secretory reactivity in healthy older men.
The Journal of clinical endocrinology and metabolism 2001;86(2):529-35.
2001: Veldhuis J D; Pincus S M; Mitamura R; Yano K; Suzuki N; Ito Y; Makita Y; Okuno A
Developmentally delimited emergence of more orderly luteinizing hormone and testosterone secretion during late prepuberty in boys.
The Journal of clinical endocrinology and metabolism 2001;86(1):80-9.
2001: Veldhuis J D; Pincus S M; Garcia-Rudaz M C; Ropelato M G; Escobar M E; Barontini M
Disruption of the joint synchrony of luteinizing hormone, testosterone, and androstenedione secretion in adolescents with polycystic ovarian syndrome.
The Journal of clinical endocrinology and metabolism 2001;86(1):72-9.
2001: Veldman R G; Frölich M; Pincus S M; Veldhuis J D; Roelfsema F
Hyperleptinemia in women with Cushing's disease is driven by high-amplitude pulsatile, but orderly and eurhythmic, leptin secretion.
European journal of endocrinology / European Federation of Endocrine Societies 2001;144(1):21-7.
2001: Schmitz O; Juhl C B; Hollingdal M; Veldhuis J D; Pørksen N; Pincus S M
Irregular circulating insulin concentrations in type 2 diabetes mellitus: an inverse relationship between circulating free fatty acid and the disorderliness of an insulin time series in diabetic and healthy individuals.
Metabolism: clinical and experimental 2001;50(1):41-6.
2001: Langendonk J G; Veldhuis J D; Burggraaf J; Schoemaker R C; Cohen A F; Meinders A E; Pijl H
Estimation of growth hormone secretion rate: impact of kinetic assumptions intrinsic to the analytical approach.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;280(1):R225-32.
2000: Garmey J C; Guthrie H D; Garrett W M; Stoler M H; Veldhuis J D
Localization and expression of low-density lipoprotein receptor, steroidogenic acute regulatory protein, cytochrome P450 side-chain cleavage and P450 17-alpha-hydroxylase/C17-20 lyase in developing swine follicles: in situ molecular hybridization and immunocytochemical studies.
Molecular and cellular endocrinology 2000;170(1-2):57-65.
2000: Castro-Fernández C; Olivares A; Söderlund D; López-Alvarenga J C; Zambrano E; Veldhuis J D; Ulloa-Aguirre A; Méndez J P
A preponderance of circulating basic isoforms is associated with decreased plasma half-life and biological to immunological ratio of gonadotropin-releasing hormone-releasable luteinizing hormone in obese men.
The Journal of clinical endocrinology and metabolism 2000;85(12):4603-10.
2000: Song S H; McIntyre S S; Shah H; Veldhuis J D; Hayes P C; Butler P C
Direct measurement of pulsatile insulin secretion from the portal vein in human subjects.
The Journal of clinical endocrinology and metabolism 2000;85(12):4491-9.
2000: Veldhuis J D
Recent neuroendocrine facets of male reproductive aging.
Experimental gerontology 2000;35(9-10):1281-308.
2000: Veldman R G; Frölich M; Pincus S M; Veldhuis J D; Roelfsema F
Apparently complete restoration of normal daily adrenocorticotropin, cortisol, growth hormone, and prolactin secretory dynamics in adults with Cushing's disease after clinically successful transsphenoidal adenomectomy.
The Journal of clinical endocrinology and metabolism 2000;85(11):4039-46.
2000: Bergendahl M; Iranmanesh A; Pastor C; Evans W S; Veldhuis J D
Homeostatic joint amplification of pulsatile and 24-hour rhythmic cortisol secretion by fasting stress in midluteal phase women: concurrent disruption of cortisol-growth hormone, cortisol-luteinizing hormone, and cortisol-leptin synchrony.
The Journal of clinical endocrinology and metabolism 2000;85(11):4028-35.
2000: Sekar N; Lavoie H A; Veldhuis J D
Concerted regulation of steroidogenic acute regulatory gene expression by luteinizing hormone and insulin (or insulin-like growth factor I) in primary cultures of porcine granulosa-luteal cells.
Endocrinology 2000;141(11):3983-92.
2000: Wideman L; Weltman J Y; Patrie J T; Bowers C Y; Shah N; Story S; Veldhuis J D; Weltman A
Synergy of L-arginine and GHRP-2 stimulation of growth hormone in men and women: modulation by exercise.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;279(4):R1467-77.
2000: Wideman L; Weltman J Y; Patrie J T; Bowers C Y; Shah N; Story S; Weltman A; Veldhuis J D
Synergy of L-arginine and growth hormone (GH)-releasing peptide-2 on GH release: influence of gender.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;279(4):R1455-66.
2000: Weltman A; Pritzlaff C J; Wideman L; Considine R V; Fryburg D A; Gutgesell M E; Hartman M L; Veldhuis J D
Intensity of acute exercise does not affect serum leptin concentrations in young men.
Medicine and science in sports and exercise 2000;32(9):1556-61.
2000: Pritzlaff C J; Wideman L; Blumer J; Jensen M; Abbott R D; Gaesser G A; Veldhuis J D; Weltman A
Catecholamine release, growth hormone secretion, and energy expenditure during exercise vs. recovery in men.
Journal of applied physiology (Bethesda, Md. : 1985) 2000;89(3):937-46.
2000: Laedtke T; Kjems L; Pørksen N; Schmitz O; Veldhuis J; Kao P C; Butler P C
Overnight inhibition of insulin secretion restores pulsatility and proinsulin/insulin ratio in type 2 diabetes.
American journal of physiology. Endocrinology and metabolism 2000;279(3):E520-8.
2000: Shah N; Evans W S; Bowers C Y; Veldhuis J D
Oral estradiol administration modulates continuous intravenous growth hormone (GH)-releasing peptide-2-driven GH secretion in postmenopausal women.
The Journal of clinical endocrinology and metabolism 2000;85(8):2649-59.
2000: Weltman A; Pritzlaff C J; Wideman L; Weltman J Y; Blumer J L; Abbott R D; Hartman M L; Veldhuis J D
Exercise-dependent growth hormone release is linked to markers of heightened central adrenergic outflow.
Journal of applied physiology (Bethesda, Md. : 1985) 2000;89(2):629-35.
2000: Hollingdal M; Juhl C B; Pincus S M; Sturis J; Veldhuis J D; Polonsky K S; Pørksen N; Schmitz O
Failure of physiological plasma glucose excursions to entrain high-frequency pulsatile insulin secretion in type 2 diabetes.
Diabetes 2000;49(8):1334-40.
2000: Zhang G; Garmey J C; Veldhuis J D
Interactive stimulation by luteinizing hormone and insulin of the steroidogenic acute regulatory (StAR) protein and 17alpha-hydroxylase/17,20-lyase (CYP17) genes in porcine theca cells.
Endocrinology 2000;141(8):2735-42.
2000: Krieg R J; Tokieda K; Chan J C; Veldhuis J D
Impact of uremia on female reproductive cyclicity, ovulation, and luteinizing hormone in the rat.
Kidney international 2000;58(2):569-74.
2000: Pincus S M; Veldhuis J D; Rogol A D
Longitudinal changes in growth hormone secretory process irregularity assessed transpubertally in healthy boys.
American journal of physiology. Endocrinology and metabolism 2000;279(2):E417-24.
2000: Nyholm B; Pørksen N; Juhl C B; Gravholt C H; Butler P C; Weeke J; Veldhuis J D; Pincus S; Schmitz O
Assessment of insulin secretion in relatives of patients with type 2 (non-insulin-dependent) diabetes mellitus: evidence of early beta-cell dysfunction.
Metabolism: clinical and experimental 2000;49(7):896-905.
2000: Veldhuis J D; Roemmich J N; Rogol A D
Gender and sexual maturation-dependent contrasts in the neuroregulation of growth hormone secretion in prepubertal and late adolescent males and females--a general clinical research center-based study.
The Journal of clinical endocrinology and metabolism 2000;85(7):2385-94.
2000: Jayes F C; Day R N; Garmey J C; Urban R J; Zhang G; Veldhuis J D
Calcium ions positively modulate follicle-stimulating hormone- and exogenous cyclic 3',5'-adenosine monophosphate-driven transcription of the P450(scc) gene in porcine granulosa cells.
Endocrinology 2000;141(7):2377-84.
2000: Bergendahl M; Iranmanesh A; Mulligan T; Veldhuis J D
Impact of age on cortisol secretory dynamics basally and as driven by nutrient-withdrawal stress.
The Journal of clinical endocrinology and metabolism 2000;85(6):2203-14.
2000: Aguirre C; Jayes F C; Veldhuis J D
Luteinizing hormone (LH) drives diverse intracellular calcium second messenger signals in isolated porcine ovarian thecal cells: preferential recruitment of intracellular Ca2+ oscillatory cells by higher concentrations of LH.
Endocrinology 2000;141(6):2220-8.
2000: Juhl C B; Schmitz O; Pincus S; Holst J J; Veldhuis J; Pørksen N
Short-term treatment with GLP-1 increases pulsatile insulin secretion in Type II diabetes with no effect on orderliness.
Diabetologia 2000;43(5):583-8.
2000: Juhl C B; Pørksen N; Hollingdal M; Sturis J; Pincus S; Veldhuis J D; Dejgaard A; Schmitz O
Repaglinide acutely amplifies pulsatile insulin secretion by augmentation of burst mass with no effect on burst frequency.
Diabetes care 2000;23(5):675-81.
2000: Keenan D M; Veldhuis J D
Explicating hypergonadotropism in postmenopausal women: a statistical model.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;278(5):R1247-57.
2000: Veldman R G; Frölich M; Pincus S M; Veldhuis J D; Roelfsema F
Growth hormone and prolactin are secreted more irregularly in patients with Cushing's disease.
Clinical endocrinology 2000;52(5):625-32.
2000: Veldhuis J D; Iranmanesh A; Godschalk M; Mulligan T
Older men manifest multifold synchrony disruption of reproductive neurohormone outflow.
The Journal of clinical endocrinology and metabolism 2000;85(4):1477-86.
2000: Lado-Abeal J; Hickox J R; Cheung T L; Veldhuis J D; Hardy D M; Norman R L
Neuroendocrine consequences of fasting in adult male macaques: effects of recombinant rhesus macaque leptin infusion.
Neuroendocrinology 2000;71(3):196-208.
2000: Juhl C B; Pørksen N; Sturis J; Hansen A P; Veldhuis J D; Pincus S; Fineman M; Schmitz O
High-frequency oscillations in circulating amylin concentrations in healthy humans.
American journal of physiology. Endocrinology and metabolism 2000;278(3):E484-90.
2000: Garmey J C; Schnorr J A; Bruns M E; Bruns D E; Seaner R M; Ferguson II J E; Luking Jayes F C; Aguirre C; Veldhuis J D
Expression of parathyroid hormone-related peptide (PTH-rp) and its receptorin the porcine ovary: regulation by transforming growth factor-beta and possible paracrine effects of granulosa cell PTH-rp secretion on theca cells.
Biology of reproduction 2000;62(2):334-9.
2000: Sekar N; Garmey J C; Veldhuis J D
Mechanisms underlying the steroidogenic synergy of insulin and luteinizing hormone in porcine granulosa cells: joint amplification of pivotal sterol-regulatory genes encoding the low-density lipoprotein (LDL) receptor, steroidogenic acute regulatory (stAR) protein and cytochrome P450 side-chain cleavage (P450scc) enzyme.
Molecular and cellular endocrinology 2000;159(1-2):25-35.
2000: Pørksen N; Juhl C; Hollingdal M; Pincus S M; Sturis J; Veldhuis J D; Schmitz O
Concordant induction of rapid in vivo pulsatile insulin secretion by recurrent punctuated glucose infusions.
American journal of physiology. Endocrinology and metabolism 2000;278(1):E162-70.
2000: Bergendahl M; Iranmanesh A; Evans W S; Veldhuis J D
Short-term fasting selectively suppresses leptin pulse mass and 24-hour rhythmic leptin release in healthy midluteal phase women without disturbing leptin pulse frequency or its entropy control (pattern orderliness).
The Journal of clinical endocrinology and metabolism 2000;85(1):207-13.
2000: Van den Berghe G; Baxter R C; Weekers F; Wouters P; Bowers C Y; Veldhuis J D
A paradoxical gender dissociation within the growth hormone/insulin-like growth factor I axis during protracted critical illness.
The Journal of clinical endocrinology and metabolism 2000;85(1):183-92.
2000: Veldhuis J D; Johnson M L
Analysis of nonequilibrium facets of pulsatile sex-steroid secretion in presence of plasma-binding proteins.
Methods in enzymology 2000;321():239-63.
2000: Veldhuis J D
Mechanisms and biological significance of pulsatile hormone secretion. Symposium proceedings. London, United Kingdom, 2-4 March 1999.
Novartis Foundation symposium 2000;227():1-4.
2000: Veldhuis J D
Nature of altered pulsatile hormone release and neuroendocrine network signalling in human ageing: clinical studies of the somatotropic, gonadotropic, corticotropic and insulin axes.
Novartis Foundation symposium 2000;227():163-85; discussion 185-9.
1999: Ropelato M G; Garcia-Rudaz M C; Castro-Fernandez C; Ulloa-Aguirre A; Escobar M E; Barontini M; Veldhuis J D
A preponderance of basic luteinizing hormone (LH) isoforms accompanies inappropriate hypersecretion of both basal and pulsatile LH in adolescents with polycystic ovarian syndrome.
The Journal of clinical endocrinology and metabolism 1999;84(12):4629-36.
1999: Mulligan T; Jaen-Vinuales A; Godschalk M; Iranmanesh A; Veldhuis J D
Synthetic somatostatin analog (octreotide) suppresses daytime growth hormone secretion equivalently in young and older men: preserved pituitary responsiveness to somatostatin's inhibition in aging.
Journal of the American Geriatrics Society 1999;47(12):1422-4.
1999: Flores J A; Garmey J C; Lahav M; Veldhuis J D
Mechanisms underlying endothelin's inhibition of FSH-stimulated progesterone production by ovarian granulosa cells.
Molecular and cellular endocrinology 1999;156(1-2):169-78.
1999: Veldhuis J D; Iranmanesh A; Demers L M; Mulligan T
Joint basal and pulsatile hypersecretory mechanisms drive the monotropic follicle-stimulating hormone (FSH) elevation in healthy older men: concurrent preservation of the orderliness of the FSH release process: a general clinical research center study.
The Journal of clinical endocrinology and metabolism 1999;84(10):3506-14.
1999: Veldhuis J D; Iranmanesh A; Mulligan T; Pincus S M
Disruption of the young-adult synchrony between luteinizing hormone release and oscillations in follicle-stimulating hormone, prolactin, and nocturnal penile tumescence (NPT) in healthy older men.
The Journal of clinical endocrinology and metabolism 1999;84(10):3498-505.
1999: Wideman L; Weltman J Y; Shah N; Story S; Veldhuis J D; Weltman A
Effects of gender on exercise-induced growth hormone release.
Journal of applied physiology (Bethesda, Md. : 1985) 1999;87(3):1154-62.
1999: Pritzlaff C J; Wideman L; Weltman J Y; Abbott R D; Gutgesell M E; Hartman M L; Veldhuis J D; Weltman A
Impact of acute exercise intensity on pulsatile growth hormone release in men.
Journal of applied physiology (Bethesda, Md. : 1985) 1999;87(2):498-504.
1999: Shah N; Aloi J; Evans W S; Veldhuis J D
Time mode of growth hormone (GH) entry into the bloodstream and steady-state plasma GH concentrations, rather than sex, estradiol, or menstrual cycle stage, primarily determine the GH elimination rate in healthy young women and men.
The Journal of clinical endocrinology and metabolism 1999;84(8):2862-9.
1999: Shah N; Evans W S; Bowers C Y; Veldhuis J D
Tripartite neuroendocrine activation of the human growth hormone (GH) axis in women by continuous 24-hour GH-releasing peptide infusion: pulsatile, entropic, and nyctohemeral mechanisms.
The Journal of clinical endocrinology and metabolism 1999;84(6):2140-50.
1999: Støving R K; Veldhuis J D; Flyvbjerg A; Vinten J; Hangaard J; Koldkjaer O G; Kristiansen J; Hagen C
Jointly amplified basal and pulsatile growth hormone (GH) secretion and increased process irregularity in women with anorexia nervosa: indirect evidence for disruption of feedback regulation within the GH-insulin-like growth factor I axis.
The Journal of clinical endocrinology and metabolism 1999;84(6):2056-63.
1999: Meneilly G S; Veldhuis J D; Elahi D
Disruption of the pulsatile and entropic modes of insulin release during an unvarying glucose stimulus in elderly individuals.
The Journal of clinical endocrinology and metabolism 1999;84(6):1938-43.
1999: Shah N; Evans W S; Veldhuis J D
Actions of estrogen on pulsatile, nyctohemeral, and entropic modes of growth hormone secretion.
The American journal of physiology 1999;276(5 Pt 2):R1351-8.
1999: Van den Berghe G; Wouters P; Weekers F; Mohan S; Baxter R C; Veldhuis J D; Bowers C Y; Bouillon R
Reactivation of pituitary hormone release and metabolic improvement by infusion of growth hormone-releasing peptide and thyrotropin-releasing hormone in patients with protracted critical illness.
The Journal of clinical endocrinology and metabolism 1999;84(4):1311-23.
1999: Groote Veldman R; van den Berg G; Pincus S M; Frölich M; Veldhuis J D; Roelfsema F
Increased episodic release and disorderliness of prolactin secretion in both micro- and macroprolactinomas.
European journal of endocrinology / European Federation of Endocrine Societies 1999;140(3):192-200.
1999: Bergendahl M; Evans W S; Pastor C; Patel A; Iranmanesh A; Veldhuis J D
Short-term fasting suppresses leptin and (conversely) activates disorderly growth hormone secretion in midluteal phase women--a clinical research center study.
The Journal of clinical endocrinology and metabolism 1999;84(3):883-94.
1999: Veldhuis J D
Recent insights into neuroendocrine mechanisms of aging of the human male hypothalamic-pituitary-gonadal axis.
Journal of andrology 1999;20(1):1-17.
1999: Van den Berghe G; Wouters P; Bowers C Y; de Zegher F; Bouillon R; Veldhuis J D
Growth hormone-releasing peptide-2 infusion synchronizes growth hormone, thyrotrophin and prolactin release in prolonged critical illness.
European journal of endocrinology / European Federation of Endocrine Societies 1999;140(1):17-22.
1999: Feneberg R; Sparber M; Veldhuis J D; Mehls O; Ritz E; Schaefer F
Synchronous fluctuations of blood insulin and lactate concentrations in humans.
The Journal of clinical endocrinology and metabolism 1999;84(1):220-7.
1999: LaVoie H A; Garmey J C; Day R N; Veldhuis J D
Concerted regulation of low density lipoprotein receptor gene expression by follicle-stimulating hormone and insulin-like growth factor I in porcine granulosa cells: promoter activation, messenger ribonucleic acid stability, and sterol feedback.
Endocrinology 1999;140(1):178-86.
1999: LaVoie H A; Garmey J C; Veldhuis J D
Mechanisms of insulin-like growth factor I augmentation of follicle-stimulating hormone-induced porcine steroidogenic acute regulatory protein gene promoter activity in granulosa cells.
Endocrinology 1999;140(1):146-53.
1998: García-Rudaz M C; Ropelato M G; Escobar M E; Veldhuis J D; Barontini M
Augmented frequency and mass of LH discharged per burst are accompanied by marked disorderliness of LH secretion in adolescents with polycystic ovary syndrome.
European journal of endocrinology / European Federation of Endocrine Societies 1998;139(6):621-30.
1998: Giustina A; Veldhuis J D
Pathophysiology of the neuroregulation of growth hormone secretion in experimental animals and the human.
Endocrine reviews 1998;19(6):717-97.
1998: Keenan D M; Veldhuis J D; Yang R
Joint recovery of pulsatile and basal hormone secretion by stochastic nonlinear random-effects analysis.
The American journal of physiology 1998;275(6 Pt 2):R1939-49.
1998: Matt D W; Gilson M P; Sales T E; Krieg R J; Kerbeshian M C; Veldhuis J D; Evans W S
Characterization of attenuated proestrous luteinizing hormone surges in middle-aged rats by deconvolution analysis.
Biology of reproduction 1998;59(6):1477-82.
1998: Fliser D; Veldhuis J D; Dikow R; Schmidt-Gayk H; Ritz E
Effects of acute ACE inhibition on pulsatile renin and aldosterone secretion and their synchrony.
Hypertension 1998;32(5):929-34.
1998: Schmitt C P; Huber D; Mehls O; Maiwald J; Stein G; Veldhuis J D; Ritz E; Schaefer F
Altered instantaneous and calcium-modulated oscillatory PTH secretion patterns in patients with secondary hyperparathyroidism.
Journal of the American Society of Nephrology : JASN 1998;9(10):1832-44.
1998: Winters T A; Hanten J A; Veldhuis J D
In situ amplification of the cytochrome P-450 cholesterol side-chain cleavage enzyme mRNA in single porcine granulosa cells by IGF-1 and FSH acting alone or in concert.
Endocrine 1998;9(1):57-63.
1998: Goodman W G; Veldhuis J D; Belin T R; Van Herle A J; Juppner H; Salusky I B
Calcium-sensing by parathyroid glands in secondary hyperparathyroidism.
The Journal of clinical endocrinology and metabolism 1998;83(8):2765-72.
1998: Flores J A; Aguirre C; Sharma O P; Veldhuis J D
Luteinizing hormone (LH) stimulates both intracellular calcium ion ([Ca2+]i) mobilization and transmembrane cation influx in single ovarian (granulosa) cells: recruitment as a cellular mechanism of LH-[Ca2+]i dose response.
Endocrinology 1998;139(8):3606-12.
1998: Iranmanesh A; South S; Liem A Y; Clemmons D; Thorner M O; Weltman A; Veldhuis J D
Unequal impact of age, percentage body fat, and serum testosterone concentrations on the somatotrophic, IGF-I, and IGF-binding protein responses to a three-day intravenous growth hormone-releasing hormone pulsatile infusion in men.
European journal of endocrinology / European Federation of Endocrine Societies 1998;139(1):59-71.
1998: Keenan D M; Veldhuis J D
A biomathematical model of time-delayed feedback in the human male hypothalamic-pituitary-Leydig cell axis.
The American journal of physiology 1998;275(1 Pt 1):E157-76.
1998: Weltman A; Weltman J Y; Kanaley J A; Rogol A D; Veldhuis J D
Repeated bouts of exercise alter the blood lactate-RPE relation.
Medicine and science in sports and exercise 1998;30(7):1113-7.
1998: Canny B J; Young I R; Veldhuis J D
Hypothalamo-pituitary disconnection of the late-gestation ovine fetus results in profound changes in cortisol secretion that are not reflected in commensurate changes in adrenocorticotropin secretion.
Endocrinology 1998;139(7):3210-9.
1998: Bergendahl M; Aloi J A; Iranmanesh A; Mulligan T M; Veldhuis J D
Fasting suppresses pulsatile luteinizing hormone (LH) secretion and enhances orderliness of LH release in young but not older men.
The Journal of clinical endocrinology and metabolism 1998;83(6):1967-75.
1998: Roelfsema F; van den Berg G; van Dulken H; Veldhuis J D; Pincus S M
Pituitary apoplexy in acromegaly, a long-term follow-up study in two patients.
Journal of endocrinological investigation 1998;21(5):298-303.
1998: Roubenoff R; Rall L C; Veldhuis J D; Kehayias J J; Rosen C; Nicolson M; Lundgren N; Reichlin S
The relationship between growth hormone kinetics and sarcopenia in postmenopausal women: the role of fat mass and leptin.
The Journal of clinical endocrinology and metabolism 1998;83(5):1502-6.
1998: Roemmich J N; Clark P A; Mai V; Berr S S; Weltman A; Veldhuis J D; Rogol A D
Alterations in growth and body composition during puberty: III. Influence of maturation, gender, body composition, fat distribution, aerobic fitness, and energy expenditure on nocturnal growth hormone release.
The Journal of clinical endocrinology and metabolism 1998;83(5):1440-7.
1998: Veldhuis J D
Neuroendocrine control of pulsatile growth hormone release in the human: relationship with gender.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 1998;8 Suppl B():49-59.
1998: Veldhuis J D; Pincus S M
Orderliness of hormone release patterns: a complementary measure to conventional pulsatile and circadian analyses.
European journal of endocrinology / European Federation of Endocrine Societies 1998;138(4):358-62.
1998: Matt D W; Kauma S W; Pincus S M; Veldhuis J D; Evans W S
Characteristics of luteinizing hormone secretion in younger versus older premenopausal women.
American journal of obstetrics and gynecology 1998;178(3):504-10.
1998: van den Berg G; Pincus S M; Frölich M; Veldhuis J D; Roelfsema F
Reduced disorderliness of growth hormone release in biochemically inactive acromegaly after pituitary surgery.
European journal of endocrinology / European Federation of Endocrine Societies 1998;138(2):164-9.
1998: Roelfsema F; Pincus S M; Veldhuis J D
Patients with Cushing's disease secrete adrenocorticotropin and cortisol jointly more asynchronously than healthy subjects.
The Journal of clinical endocrinology and metabolism 1998;83(2):688-92.
1998: Van den Berghe G; de Zegher F; Baxter R C; Veldhuis J D; Wouters P; Schetz M; Verwaest C; Van der Vorst E; Lauwers P; Bouillon R; Bowers C Y
Neuroendocrinology of prolonged critical illness: effects of exogenous thyrotropin-releasing hormone and its combination with growth hormone secretagogues.
The Journal of clinical endocrinology and metabolism 1998;83(2):309-19.
1998: Schmitt C P; Schaefer F; Huber D; Zahn I; Veldhuis J D; Ritz E; Mehls O
1,25(OH)2-vitamin D3 reduces spontaneous and hypocalcemia-stimulated pulsatile component of parathyroid hormone secretion.
Journal of the American Society of Nephrology : JASN 1998;9(1):54-62.
1998: Pørksen N; Grøfte B; Nyholm B; Holst J J; Pincus S M; Veldhuis J D; Schmitz O; Butler P C
Glucagon-like peptide 1 increases mass but not frequency or orderliness of pulsatile insulin secretion.
Diabetes 1998;47(1):45-9.
1997: Meneilly G S; Ryan A S; Veldhuis J D; Elahi D
Increased disorderliness of basal insulin release, attenuated insulin secretory burst mass, and reduced ultradian rhythmicity of insulin secretion in older individuals.
The Journal of clinical endocrinology and metabolism 1997;82(12):4088-93.
1997: Van den Berghe G; de Zegher F; Veldhuis J D; Wouters P; Gouwy S; Stockman W; Weekers F; Schetz M; Lauwers P; Bouillon R; Bowers C Y
Thyrotrophin and prolactin release in prolonged critical illness: dynamics of spontaneous secretion and effects of growth hormone-secretagogues.
Clinical endocrinology 1997;47(5):599-612.
1997: Kanaley J A; Weltman J Y; Veldhuis J D; Rogol A D; Hartman M L; Weltman A
Human growth hormone response to repeated bouts of aerobic exercise.
Journal of applied physiology (Bethesda, Md. : 1985) 1997;83(5):1756-61.
1997: Pincus S M; Veldhuis J D; Mulligan T; Iranmanesh A; Evans W S
Effects of age on the irregularity of LH and FSH serum concentrations in women and men.
The American journal of physiology 1997;273(5 Pt 1):E989-95.
1997: Pørksen N; Nyholm B; Veldhuis J D; Butler P C; Schmitz O
In humans at least 75% of insulin secretion arises from punctuated insulin secretory bursts.
The American journal of physiology 1997;273(5 Pt 1):E908-14.
1997: Fliser D; Schaefer F; Schmid D; Veldhuis J D; Ritz E
Angiotensin II affects basal, pulsatile, and glucose-stimulated insulin secretion in humans.
Hypertension 1997;30(5):1156-61.
1997: Fryburg D A; Weltman A; Jahn L A; Weltman J Y; Samojlik E; Hintz R L; Veldhuis J D
Short-term modulation of the androgen milieu alters pulsatile, but not exercise- or growth hormone (GH)-releasing hormone-stimulated GH secretion in healthy men: impact of gonadal steroid and GH secretory changes on metabolic outcomes.
The Journal of clinical endocrinology and metabolism 1997;82(11):3710-9.
1997: Sun F; Berry D J; Leong D A; Veldhuis J D
Recruitment of individually (all-or-none) responding cells, rather than amplitude enhancement, is the single-cell mechanism subserving the dose-responsive activation of intracellular calcium second messenger signaling by the human luteinizing-hormone receptor.
Endocrine 1997;7(2):219-26.
1997: Friend K; Iranmanesh A; Login I S; Veldhuis J D
Pyridostigmine treatment selectively amplifies the mass of GH secreted per burst without altering GH burst frequency, half-life, basal GH secretion or the orderliness of GH release.
European journal of endocrinology / European Federation of Endocrine Societies 1997;137(4):377-86.
1997: Veldhuis J D; Metzger D L; Martha P M; Mauras N; Kerrigan J R; Keenan B; Rogol A D; Pincus S M
Estrogen and testosterone, but not a nonaromatizable androgen, direct network integration of the hypothalamo-somatotrope (growth hormone)-insulin-like growth factor I axis in the human: evidence from pubertal pathophysiology and sex-steroid hormone replacement.
The Journal of clinical endocrinology and metabolism 1997;82(10):3414-20.
1997: Keenan D M; Veldhuis J D
Stochastic model of admixed basal and pulsatile hormone secretion as modulated by a deterministic oscillator.
The American journal of physiology 1997;273(3 Pt 2):R1182-92.
1997: Clark P A; Iranmanesh A; Veldhuis J D; Rogol A D
Comparison of pulsatile luteinizing hormone secretion between prepubertal children and young adults: evidence for a mass/amplitude-dependent difference without gender or day/night contrasts.
The Journal of clinical endocrinology and metabolism 1997;82(9):2950-5.
1997: Veldhuis J D; Iranmanesh A; Weltman A
Elements in the pathophysiology of diminished growth hormone (GH) secretion in aging humans.
Endocrine 1997;7(1):41-8.
1997: LaVoie H A; Benoit A M; Garmey J C; Dailey R A; Wright D J; Veldhuis J D
Coordinate developmental expression of genes regulating sterol economy and cholesterol side-chain cleavage in the porcine ovary.
Biology of reproduction 1997;57(2):402-7.
1997: Zwart A D; Iranmanesh A; Veldhuis J D
Disparate serum free testosterone concentrations and degrees of hypothalamo-pituitary-luteinizing hormone suppression are achieved by continuous versus pulsatile intravenous androgen replacement in men: a clinical experimental model of ketoconazole-induced reversible hypoandrogenemia with controlled testosterone add-back.
The Journal of clinical endocrinology and metabolism 1997;82(7):2062-9.
1997: Goodman W G; Veldhuis J D; Belin T R; Juppner H; Salusky I B
Suppressive effect of calcium on parathyroid hormone release in adynamic renal osteodystrophy and secondary hyperparathyroidism.
Kidney international 1997;51(5):1590-5.
1997: Aloi J A; Bergendahl M; Iranmanesh A; Veldhuis J D
Pulsatile intravenous gonadotropin-releasing hormone administration averts fasting-induced hypogonadotropism and hypoandrogenemia in healthy, normal weight men.
The Journal of clinical endocrinology and metabolism 1997;82(5):1543-8.
1997: Veldhuis J D
How does one get at glandular secretion, when only hormone concentrations are measured?
Clinical endocrinology 1997;46(4):397-400.
1997: van den Berg G; Pincus S M; Veldhuis J D; Frölich M; Roelfsema F
Greater disorderliness of ACTH and cortisol release accompanies pituitary-dependent Cushing's disease.
European journal of endocrinology / European Federation of Endocrine Societies 1997;136(4):394-400.
1997: Veldhuis J D; Iranmanesh A; Samojlik E; Urban R J
Differential sex steroid negative feedback regulation of pulsatile follicle-stimulating hormone secretion in healthy older men: deconvolution analysis and steady-state sex-steroid hormone infusions in frequently sampled healthy older individuals.
The Journal of clinical endocrinology and metabolism 1997;82(4):1248-54.
1997: Giustina A; Scalvini T; Tassi C; Desenzani P; Poiesi C; Wehrenberg W B; Rogol A D; Veldhuis J D
Maturation of the regulation of growth hormone secretion in young males with hypogonadotropic hypogonadism pharmacologically exposed to progressive increments in serum testosterone.
The Journal of clinical endocrinology and metabolism 1997;82(4):1210-9.
1997: Pørksen N; Hussain M A; Bianda T L; Nyholm B; Christiansen J S; Butler P C; Veldhuis J D; Froesch E R; Schmitz O
IGF-I inhibits burst mass of pulsatile insulin secretion at supraphysiological and low IGF-I infusion rates.
The American journal of physiology 1997;272(3 Pt 1):E352-8.
1997: Veldhuis J D; Zwart A D; Iranmanesh A
Neuroendocrine mechanisms by which selective Leydig cell castration unleashes increased pulsatile LH release.
The American journal of physiology 1997;272(2 Pt 2):R464-74.
1997: Schmitz O; Pørksen N; Nyholm B; Skjaerbaek C; Butler P C; Veldhuis J D; Pincus S M
Disorderly and nonstationary insulin secretion in relatives of patients with NIDDM.
The American journal of physiology 1997;272(2 Pt 1):E218-26.
1997: Van den Berghe G; de Zegher F; Veldhuis J D; Wouters P; Awouters M; Verbruggen W; Schetz M; Verwaest C; Lauwers P; Bouillon R; Bowers C Y
The somatotropic axis in critical illness: effect of continuous growth hormone (GH)-releasing hormone and GH-releasing peptide-2 infusion.
The Journal of clinical endocrinology and metabolism 1997;82(2):590-9.
1997: Veldhuis J D; Norton J A; Wells S A; Vinik A I; Perry R R
Surgical versus medical management of multiple endocrine neoplasia (MEN) type I.
The Journal of clinical endocrinology and metabolism 1997;82(2):357-64.
1997: Balasubramanian K; Lavoie H A; Garmey J C; Stocco D M; Veldhuis J D
Regulation of porcine granulosa cell steroidogenic acute regulatory protein (StAR) by insulin-like growth factor I: synergism with follicle-stimulating hormone or protein kinase A agonist.
Endocrinology 1997;138(1):433-9.
1996: Veldhuis J D; Iranmanesh A
Physiological regulation of the human growth hormone (GH)-insulin-like growth factor type I (IGF-I) axis: predominant impact of age, obesity, gonadal function, and sleep.
Sleep 1996;19(10 Suppl):S221-4.
1996: Chapman I M; Bach M A; Van Cauter E; Farmer M; Krupa D; Taylor A M; Schilling L M; Cole K Y; Skiles E H; Pezzoli S S; Hartman M L; Veldhuis J D; Gormley G J; Thorner M O
Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of a GH secretogogue (MK-677) in healthy elderly subjects.
The Journal of clinical endocrinology and metabolism 1996;81(12):4249-57.
1996: Schmitt C P; Schaefer F; Bruch A; Veldhuis J D; Schmidt-Gayk H; Stein G; Ritz E; Mehls O
Control of pulsatile and tonic parathyroid hormone secretion by ionized calcium.
The Journal of clinical endocrinology and metabolism 1996;81(12):4236-43.
1996: Johnson M L; Veldhuis J D; Lampl M
Is growth saltatory? The usefulness and limitations of frequency distributions in analyzing pulsatile data.
Endocrinology 1996;137(12):5197-204.
1996: Bergendahl M; Evans W S; Veldhuis J D
Current concepts on ultradian rhythms of luteinizing hormone secretion in the human.
Human reproduction update 1996;2(6):507-18.
1996: Pincus S M; Mulligan T; Iranmanesh A; Gheorghiu S; Godschalk M; Veldhuis J D
Older males secrete luteinizing hormone and testosterone more irregularly, and jointly more asynchronously, than younger males.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(24):14100-5.
1996: Martha P M; Rogol A D; Veldhuis J D; Blizzard R M
A longitudinal assessment of hormonal and physical alterations during normal puberty in boys. III. The neuroendocrine growth hormone axis during late prepuberty.
The Journal of clinical endocrinology and metabolism 1996;81(11):4068-74.
1996: Zwart A D; Urban R J; Odell W D; Veldhuis J D
Contrasts in the gonadotropin-releasing hormone dose-response relationships for luteinizing hormone, follicle-stimulating hormone and alpha-subunit release in young versus older men: appraisal with high-specificity immunoradiometric assay and deconvolution analysis.
European journal of endocrinology / European Federation of Endocrine Societies 1996;135(4):399-406.
1996: Friend K; Iranmanesh A; Veldhuis J D
The orderliness of the growth hormone (GH) release process and the mean mass of GH secreted per burst are highly conserved in individual men on successive days.
The Journal of clinical endocrinology and metabolism 1996;81(10):3746-53.
1996: Booth R A; Weltman J Y; Yankov V I; Murray J; Davison T S; Rogol A D; Asplin C M; Johnson M L; Veldhuis J D; Evans W S
Mode of pulsatile follicle-stimulating hormone secretion in gonadal hormone-sufficient and -deficient women--a clinical research center study.
The Journal of clinical endocrinology and metabolism 1996;81(9):3208-14.
1996: van den Berg G; Veldhuis J D; Frölich M; Roelfsema F
An amplitude-specific divergence in the pulsatile mode of growth hormone (GH) secretion underlies the gender difference in mean GH concentrations in men and premenopausal women.
The Journal of clinical endocrinology and metabolism 1996;81(7):2460-7.
1996: Veldhuis J D
Neuroendocrine mechanisms mediating awakening of the human gonadotropic axis in puberty.
Pediatric nephrology (Berlin, Germany) 1996;10(3):304-17.
1996: Wright N M; Papadea N; Willi S; Veldhuis J D; Pandey J P; Key L L; Bell N H
Demonstration of a lack of racial difference in secretion of growth hormone despite a racial difference in bone mineral density in premenopausal women--a Clinical Research Center study.
The Journal of clinical endocrinology and metabolism 1996;81(3):1023-6.
1996: Lahav M; Garmey J C; Veldhuis J D
Paradoxical effect of 3-isobutyl-1-methylxanthine on cytochrome P450 cholesterol side-chain cleavage mRNA accumulation in porcine granulosa cells.
Molecular and cellular endocrinology 1996;117(2):203-10.
1996: Veldhuis J D
Gender differences in secretory activity of the human somatotropic (growth hormone) axis.
European journal of endocrinology / European Federation of Endocrine Societies 1996;134(3):287-95.
1996: Bergendahl M; Vance M L; Iranmanesh A; Thorner M O; Veldhuis J D
Fasting as a metabolic stress paradigm selectively amplifies cortisol secretory burst mass and delays the time of maximal nyctohemeral cortisol concentrations in healthy men.
The Journal of clinical endocrinology and metabolism 1996;81(2):692-9.
1996: Reyes-Fuentes A; Chavarría M E; Carrera A; Aguilera G; Rosado A; Samojlik E; Iranmanesh A; Veldhuis J D
Alterations in pulsatile luteinizing hormone and follicle-stimulating hormone secretion in idiopathic oligoasthenospermic men: assessment by deconvolution analysis--a clinical research center study.
The Journal of clinical endocrinology and metabolism 1996;81(2):524-9.
1996: Pincus S M; Gevers E F; Robinson I C; van den Berg G; Roelfsema F; Hartman M L; Veldhuis J D
Females secrete growth hormone with more process irregularity than males in both humans and rats.
The American journal of physiology 1996;270(1 Pt 1):E107-15.
1996: Schaefer F; Baumann G; Haffner D; Faunt L M; Johnson M L; Mercado M; Ritz E; Mehls O; Veldhuis J D
Multifactorial control of the elimination kinetics of unbound (free) growth hormone (GH) in the human: regulation by age, adiposity, renal function, and steady state concentrations of GH in plasma.
The Journal of clinical endocrinology and metabolism 1996;81(1):22-31.
1995: van den Berg G; Frölich M; Veldhuis J D; Roelfsema F
Combined amplification of the pulsatile and basal modes of adrenocorticotropin and cortisol secretion in patients with Cushing's disease: evidence for decreased responsiveness of the adrenal glands.
The Journal of clinical endocrinology and metabolism 1995;80(12):3750-7.
1995: Veldhuis J D; Liem A Y; South S; Weltman A; Weltman J; Clemmons D A; Abbott R; Mulligan T; Johnson M L; Pincus S
Differential impact of age, sex steroid hormones, and obesity on basal versus pulsatile growth hormone secretion in men as assessed in an ultrasensitive chemiluminescence assay.
The Journal of clinical endocrinology and metabolism 1995;80(11):3209-22.
1995: Maitra A; LaVoie H A; Day R N; Garmey J C; Veldhuis J D
Regulation of porcine granulosa cell 3-hydroxy-3-methylglutaryl coenzyme A reductase by insulin and insulin-like growth factor I: synergism with follicle-stimulating hormone or protein kinase A agonist.
Endocrinology 1995;136(11):5111-7.
1995: Flores J A; Winters T A; Knight J W; Veldhuis J D
Nature of endothelin binding in the porcine ovary.
Endocrinology 1995;136(11):5014-9.
1995: Mulligan T; Iranmanesh A; Gheorghiu S; Godschalk M; Veldhuis J D
Amplified nocturnal luteinizing hormone (LH) secretory burst frequency with selective attenuation of pulsatile (but not basal) testosterone secretion in healthy aged men: possible Leydig cell desensitization to endogenous LH signaling--a clinical research center study.
The Journal of clinical endocrinology and metabolism 1995;80(10):3025-31.
1995: Wright N M; Renault J; Willi S; Veldhuis J D; Pandey J P; Gordon L; Key L L; Bell N H
Greater secretion of growth hormone in black than in white men: possible factor in greater bone mineral density--a clinical research center study.
The Journal of clinical endocrinology and metabolism 1995;80(8):2291-7.
1995: Benoit A M; Veldhuis J D
Differential effects of pulsatile versus continuous follicle-stimulating hormone delivery on the production of cyclic adenosine 5'-monophosphates and the accumulation of cytochrome P450 cholesterol side-chain cleavage enzyme mRNA in perifused porcine granulosa cells.
Biology of reproduction 1995;53(1):46-54.
1995: Lahav M; Garmey J C; Shupnik M A; Veldhuis J D
Dual actions of phorbol ester on cytochrome P450 cholesterol side-chain cleavage messenger ribonucleic acid accumulation in porcine granulosa cells.
Biology of reproduction 1995;52(5):972-81.
1995: Chavarría E; Reyes A; Carrera A; Aguilera G; Rosado A; Veldhuis J D
[Kinetic study of pulsatility of gonadotropin and testosterone secretion in normospermic fertile and infertile men with idiopathic oligo-asthenozoospermia]
Ginecología y obstetricia de México 1995;63():74-89.
1995: Siragy H M; Vieweg W V; Pincus S; Veldhuis J D
Increased disorderliness and amplified basal and pulsatile aldosterone secretion in patients with primary aldosteronism.
The Journal of clinical endocrinology and metabolism 1995;80(1):28-33.
1994: Veldhuis J D; Urban R J; Dufau M L
Differential responses of biologically active luteinizing hormone secretion in older versus young men to interruption of androgen negative feedback.
The Journal of clinical endocrinology and metabolism 1994;79(6):1763-70.
1994: van den Berg G; Frölich M; Veldhuis J D; Roelfsema F
Growth hormone secretion in recently operated acromegalic patients.
The Journal of clinical endocrinology and metabolism 1994;79(6):1706-15.
1994: Veldhuis J D; Iranmanesh A; Wilkowski M J; Samojlik E
Neuroendocrine alterations in the somatotropic and lactotropic axes in uremic men.
European journal of endocrinology / European Federation of Endocrine Societies 1994;131(5):489-98.
1994: Schaefer F; van Kaick B; Veldhuis J D; Stein G; Schärer K; Robertson W R; Ritz E
Changes in the kinetics and biopotency of luteinizing hormone in hemodialyzed men during treatment with recombinant human erythropoietin.
Journal of the American Society of Nephrology : JASN 1994;5(5):1208-15.
1994: Van den Berghe G; de Zegher F; Lauwers P; Veldhuis J D
Luteinizing hormone secretion and hypoandrogenaemia in critically ill men: effect of dopamine.
Clinical endocrinology 1994;41(5):563-9.
1994: Van den Berghe G; de Zegher F; Lauwers P; Veldhuis J D
Growth hormone secretion in critical illness: effect of dopamine.
The Journal of clinical endocrinology and metabolism 1994;79(4):1141-6.
1994: Griffin M L; South S A; Yankov V I; Booth R A; Asplin C M; Veldhuis J D; Evans W S
Insulin-dependent diabetes mellitus and menstrual dysfunction.
Annals of medicine 1994;26(5):331-40.
1994: Hartman M L; Pincus S M; Johnson M L; Matthews D H; Faunt L M; Vance M L; Thorner M O; Veldhuis J D
Enhanced basal and disorderly growth hormone secretion distinguish acromegalic from normal pulsatile growth hormone release.
The Journal of clinical investigation 1994;94(3):1277-88.
1994: de Zegher F; Vanhole C; Van den Berghe G; Devlieger H; Eggermont E; Veldhuis J D
Properties of thyroid-stimulating hormone and cortisol secretion by the human newborn on the day of birth.
The Journal of clinical endocrinology and metabolism 1994;79(2):576-81.
1994: Loudon A S; Wayne N L; Krieg R; Iranmanesh A; Veldhuis J D; Menaker M
Ultradian endocrine rhythms are altered by a circadian mutation in the Syrian hamster.
Endocrinology 1994;135(2):712-8.
1994: Sharma O P; Flores J A; Leong D A; Veldhuis J D
Mechanisms by which endothelin-1 stimulates increased cytosolic free calcium ion concentrations in single rat Sertoli cells.
Endocrinology 1994;135(1):127-34.
1994: Veldhuis J D; Iranmanesh A; Lizarralde G; Urban R J
Combined deficits in the somatotropic and gonadotropic axes in healthy aging men: an appraisal of neuroendocrine mechanisms by deconvolution analysis.
Neurobiology of aging 1994;15(4):509-17.
1994: Chapman I M; Hartman M L; Straume M; Johnson M L; Veldhuis J D; Thorner M O
Enhanced sensitivity growth hormone (GH) chemiluminescence assay reveals lower postglucose nadir GH concentrations in men than women.
The Journal of clinical endocrinology and metabolism 1994;78(6):1312-9.
1994: Sharma O P; Flores J A; Leong D A; Veldhuis J D
Cellular basis for follicle-stimulating hormone-stimulated calcium signaling in single rat Sertoli cells: possible dissociation from effects of adenosine 3',5'-monophosphate.
Endocrinology 1994;134(4):1915-23.
1994: Schaefer F; Daschner M; Veldhuis J D; Oh J; Qadri F; Schärer K
In vivo alterations in the gonadotropin-releasing hormone pulse generator and the secretion and clearance of luteinizing hormone in the uremic castrate rat.
Neuroendocrinology 1994;59(3):285-96.
1994: Weltman A; Weltman J Y; Hartman M L; Abbott R D; Rogol A D; Evans W S; Veldhuis J D
Relationship between age, percentage body fat, fitness, and 24-hour growth hormone release in healthy young adults: effects of gender.
The Journal of clinical endocrinology and metabolism 1994;78(3):543-8.
1994: Kerrigan J R; Veldhuis J D; Rogol A D
Androgen-receptor blockade enhances pulsatile luteinizing hormone production in late pubertal males: evidence for a hypothalamic site of physiologic androgen feedback action.
Pediatric research 1994;35(1):102-6.
1994: Veldhuis J D; Johnson M L
Testing pulse detection algorithms with simulations of episodically pulsatile substrate, metabolite, or hormone release.
Methods in enzymology 1994;240():377-415.
1994: Veldhuis J D; Faunt L M; Johnson M L
Analysis of nonequilibrium dynamics of bound, free, and total plasma ligand concentrations over time following nonlinear secretory inputs: kinetics of two or more hormones pulsed into compartments containing multiple variable-affinity binding proteins.
Methods in enzymology 1994;240():349-77.
1994: Straume M; Veldhuis J D; Johnson M L
Model-independent quantification of measurement error: empirical estimation of discrete variance function profiles based on standard curves.
Methods in enzymology 1994;240():121-50.
1994: Veldhuis J D; Johnson M L
Analytical methods for evaluating episodic secretory activity within neuroendocrine axes.
Neuroscience and biobehavioral reviews 1994;18(4):605-12.
1993: Nieves-Rivera F; Kerrigan J R; Krieg R J; Egan J; Hwang L J; Truumees E; Veldhuis J D; Evans W S; Rogol A D
Altered growth hormone (GH) secretion in vivo and in vitro in the diabetes-prone BB/Worcester rat.
Growth regulation 1993;3(4):235-44.
1993: De Zegher F; Van Den Berghe G; Devlieger H; Eggermont E; Veldhuis J D
Dopamine inhibits growth hormone and prolactin secretion in the human newborn.
Pediatric research 1993;34(5):642-5.
1993: Nieves-Rivera F; Rogol A D; Veldhuis J D; Branscom D K; Martha P M; Clarke W L
Alterations in growth hormone secretion and clearance in adolescent boys with insulin-dependent diabetes mellitus.
The Journal of clinical endocrinology and metabolism 1993;77(3):638-43.
1993: Metzger D L; Wright N M; Veldhuis J D; Rogol A D; Kerrigan J R
Characterization of pulsatile secretion and clearance of plasma cortisol in premature and term neonates using deconvolution analysis.
The Journal of clinical endocrinology and metabolism 1993;77(2):458-63.
1993: Garmey J C; Day R N; Day K H; Veldhuis J D
Mechanisms of regulation of ovarian sterol metabolism by insulin-like growth factor type II: in vitro studies with swine granulosa cells.
Endocrinology 1993;133(2):800-8.
1993: Thompson D L; Weltman J Y; Rogol A D; Metzger D L; Veldhuis J D; Weltman A
Cholinergic and opioid involvement in release of growth hormone during exercise and recovery.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;75(2):870-8.
1993: Roelfsema F; van den Berg G; Frölich M; Veldhuis J D; van Eijk A; Buurman M M; Etman B H
Sex-dependent alteration in cortisol response to endogenous adrenocorticotropin.
The Journal of clinical endocrinology and metabolism 1993;77(1):234-40.
1993: Veldhuis J D; Johnson M L; Gallo R V
Reanalysis of the rat proestrous LH surge by deconvolution analysis.
The American journal of physiology 1993;265(1 Pt 2):R240-5.
1993: Kerrigan J R; Veldhuis J D; Leyo S A; Iranmanesh A; Rogol A D
Estimation of daily cortisol production and clearance rates in normal pubertal males by deconvolution analysis.
The Journal of clinical endocrinology and metabolism 1993;76(6):1505-10.
1993: Iranmanesh A; Lizarralde G; Veldhuis J D
Coordinate activation of the corticotropic axis by insulin-induced hypoglycemia: simultaneous estimates of beta-endorphin, adrenocorticotropin and cortisol secretion and disappearance in normal men.
Acta endocrinologica 1993;128(6):521-8.
1993: de Zegher F; Devlieger H; Veldhuis J D
Properties of growth hormone and prolactin hypersecretion by the human infant on the day of birth.
The Journal of clinical endocrinology and metabolism 1993;76(5):1177-81.
1993: Flores J A; Garmey J C; Nestler J E; Veldhuis J D
Sites of inhibition of steroidogenesis by activation of protein kinase-C in swine ovarian (granulosa) cells.
Endocrinology 1993;132(5):1983-90.
1993: South S A; Asplin C M; Carlsen E C; Booth R A; Weltman J Y; Johnson M L; Veldhuis J D; Evans W S
Alterations in luteinizing hormone secretory activity in women with insulin-dependent diabetes mellitus and secondary amenorrhea.
The Journal of clinical endocrinology and metabolism 1993;76(4):1048-53.
1993: Kerrigan J R; Martha P M; Veldhuis J D; Blizzard R M; Rogol A D
Altered growth hormone secretory dynamics in prepubertal males with constitutional delay of growth.
Pediatric research 1993;33(3):278-83.
1993: Veldhuis J D; Wilkowski M J; Zwart A D; Urban R J; Lizarralde G; Iranmanesh A; Bolton W K
Evidence for attenuation of hypothalamic gonadotropin-releasing hormone (GnRH) impulse strength with preservation of GnRH pulse frequency in men with chronic renal failure.
The Journal of clinical endocrinology and metabolism 1993;76(3):648-54.
1993: Quyyumi S A; Pinkerton J V; Evans W S; Veldhuis J D
Estradiol amplifies the amount of luteinizing hormone (LH) secreted in response to increasing doses of gonadotropin-releasing hormone by specifically augmenting the duration of evoked LH secretory events and hence their mass.
The Journal of clinical endocrinology and metabolism 1993;76(3):594-600.
1993: Veldhuis J D; Iranmanesh A; Evans W S; Lizarralde G; Thorner M O; Vance M L
Amplitude suppression of the pulsatile mode of immunoradiometric luteinizing hormone release in fasting-induced hypoandrogenemia in normal men.
The Journal of clinical endocrinology and metabolism 1993;76(3):587-93.
1993: Veldhuis J D; Johnson M L; Faunt L M; Mercado M; Baumann G
Influence of the high-affinity growth hormone (GH)-binding protein on plasma profiles of free and bound GH and on the apparent half-life of GH. Modeling analysis and clinical applications.
The Journal of clinical investigation 1993;91(2):629-41.
1992: Rogol A D; Weltman J Y; Evans W S; Veldhuis J D; Weltman A L
Long-term endurance training alters the hypothalamic-pituitary axes for gonadotropins and growth hormone.
Endocrinology and metabolism clinics of North America 1992;21(4):817-32.
1992: de Zegher F; Devlieger H; Veldhuis J D
Pulsatile and sexually dimorphic secretion of luteinizing hormone in the human infant on the day of birth.
Pediatric research 1992;32(5):605-7.
1992: Snead D B; Stubbs C C; Weltman J Y; Evans W S; Veldhuis J D; Rogol A D; Teates C D; Weltman A
Dietary patterns, eating behaviors, and bone mineral density in women runners.
The American journal of clinical nutrition 1992;56(4):705-11.
1992: Kolp L A; Pavlou S N; Urban R J; Rivier J C; Vale W W; Veldhuis J D
Abrogation by a potent gonadotropin-releasing hormone antagonist of the estrogen/progesterone-stimulated surge-like release of luteinizing hormone and follicle-stimulating hormone in postmenopausal women.
The Journal of clinical endocrinology and metabolism 1992;75(4):993-7.
1992: Veldhuis J D; Johnson M L; Lizarralde G; Iranmanesh A
Rhythmic and nonrhythmic modes of anterior pituitary gland secretion.
Chronobiology international 1992;9(5):371-9.
1992: Veldhuis J D; Urban R J; Lizarralde G; Johnson M L; Iranmanesh A
Attenuation of luteinizing hormone secretory burst amplitude as a proximate basis for the hypoandrogenism of healthy aging in men.
The Journal of clinical endocrinology and metabolism 1992;75(3):707-13.
1992: Wright N M; Northington F J; Miller J D; Veldhuis J D; Rogol A D
Elevated growth hormone secretory rate in premature infants: deconvolution analysis of pulsatile growth hormone secretion in the neonate.
Pediatric research 1992;32(3):286-90.
1992: Flores J A; Quyyumi S; Leong D A; Veldhuis J D
Actions of endothelin-1 on swine ovarian (granulosa) cells.
Endocrinology 1992;131(3):1350-8.
1992: Weltman A; Weltman J Y; Schurrer R; Evans W S; Veldhuis J D; Rogol A D
Endurance training amplifies the pulsatile release of growth hormone: effects of training intensity.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;72(6):2188-96.
1992: Veldhuis J D; Urban R J; Dufau M L
Evidence that androgen negative feedback regulates hypothalamic gonadotropin-releasing hormone impulse strength and the burst-like secretion of biologically active luteinizing hormone in men.
The Journal of clinical endocrinology and metabolism 1992;74(6):1227-35.
1992: Faria A C; Bekenstein L W; Booth R A; Vaccaro V A; Asplin C M; Veldhuis J D; Thorner M O; Evans W S
Pulsatile growth hormone release in normal women during the menstrual cycle.
Clinical endocrinology 1992;36(6):591-6.
1992: Snead D B; Weltman A; Weltman J Y; Evans W S; Veldhuis J D; Varma M M; Teates C D; Dowling E A; Rogol A D
Reproductive hormones and bone mineral density in women runners.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;72(6):2149-56.
1992: Vieweg W V; Veldhuis J D; Carey R M
Temporal pattern of renin and aldosterone secretion in men: effects of sodium balance.
The American journal of physiology 1992;262(5 Pt 2):F871-7.
1992: Weltman A; Seip R L; Snead D; Weltman J Y; Haskvitz E M; Evans W S; Veldhuis J D; Rogol A D
Exercise training at and above the lactate threshold in previously untrained women.
International journal of sports medicine 1992;13(3):257-63.
1992: Hartman M L; Veldhuis J D; Johnson M L; Lee M M; Alberti K G; Samojlik E; Thorner M O
Augmented growth hormone (GH) secretory burst frequency and amplitude mediate enhanced GH secretion during a two-day fast in normal men.
The Journal of clinical endocrinology and metabolism 1992;74(4):757-65.
1992: Flores J A; Leong D A; Veldhuis J D
Is the calcium signal induced by follicle-stimulating hormone in swine granulosa cells mediated by adenosine cyclic 3',5'-monophosphate-dependent protein kinase?
Endocrinology 1992;130(4):1862-6.
1992: Iranmanesh A; Lizarralde G; Veldhuis J D
Robustness of the male lactotropic axis to the hyperprolactinemic stimulus of primary thyroidal failure.
The Journal of clinical endocrinology and metabolism 1992;74(3):559-64.
1992: Veldhuis J D; Johnson M L; Seneta E; Iranmanesh A
Temporal coupling among luteinizing hormone, follicle stimulating hormone, beta-endorphin and cortisol pulse episodes in vivo.
Acta endocrinologica 1992;126(3):193-200.
1992: Martha P M; Gorman K M; Blizzard R M; Rogol A D; Veldhuis J D
Endogenous growth hormone secretion and clearance rates in normal boys, as determined by deconvolution analysis: relationship to age, pubertal status, and body mass.
The Journal of clinical endocrinology and metabolism 1992;74(2):336-44.
1992: Evans W S; Sollenberger M J; Booth R A; Rogol A D; Urban R J; Carlsen E C; Johnson M L; Veldhuis J D
Contemporary aspects of discrete peak-detection algorithms. II. The paradigm of the luteinizing hormone pulse signal in women.
Endocrine reviews 1992;13(1):81-104.
1992: Veldhuis J D; Lizarralde G; Iranmanesh A
Divergent effects of short term glucocorticoid excess on the gonadotropic and somatotropic axes in normal men.
The Journal of clinical endocrinology and metabolism 1992;74(1):96-102.
1992: Veldhuis J D; Johnson M L
Deconvolution analysis of hormone data.
Methods in enzymology 1992;210():539-75.
1991: Veldhuis J D; Sotos J F; Sherman B M
Decreased metabolic clearance of endogenous growth hormone and specific alterations in the pulsatile mode of growth hormone secretion occur in prepubertal girls with Turner's syndrome. Genentech Collaborative Group.
The Journal of clinical endocrinology and metabolism 1991;73(5):1073-80.
1991: Urban R J; Padmanabhan V; Beitins I; Veldhuis J D
Metabolic clearance of human follicle-stimulating hormone assessed by radioimmunoassay, immunoradiometric assay, and in vitro Sertoli cell bioassay.
The Journal of clinical endocrinology and metabolism 1991;73(4):818-23.
1991: Flores J A; Veldhuis J D; Leong D A
Angiotensin II induces calcium release in a subpopulation of single ovarian (granulosa) cells.
Molecular and cellular endocrinology 1991;81(1-3):1-10.
1991: Nunley W C; Urban R J; Evans W S; Veldhuis J D
Preservation of pulsatile luteinizing hormone release during postpartum lactational amenorrhea.
The Journal of clinical endocrinology and metabolism 1991;73(3):629-36.
1991: Veldhuis J D; Garmey J C; Urban R J; Demers L M; Aggarwal B B
Ovarian actions of tumor necrosis factor-alpha (TNF alpha): pleiotropic effects of TNF alpha on differentiated functions of untransformed swine granulosa cells.
Endocrinology 1991;129(2):641-8.
1991: Veldhuis J D; Johnson M L; Bolton W K
Analyzing pulsatile endocrine data in patients with chronic renal failure: a brief review of deconvolution techniques.
Pediatric nephrology (Berlin, Germany) 1991;5(4):522-8.
1991: Veldhuis J D
Temporal architecture of in vivo endocrine glandular signaling: obtaining a secretory blueprint by deconvolution analysis.
Molecular and cellular endocrinology 1991;77(1-3):C63-71.
1991: Holl R W; Hartman M L; Veldhuis J D; Taylor W M; Thorner M O
Thirty-second sampling of plasma growth hormone in man: correlation with sleep stages.
The Journal of clinical endocrinology and metabolism 1991;72(4):854-61.
1991: Urban R J; Johnson M L; Veldhuis J D
In vivo biological validation and biophysical modeling of the sensitivity and positive accuracy of endocrine peak detection. II. The follicle-stimulating hormone pulse signal.
Endocrinology 1991;128(4):2008-14.
1991: Urban R J; Garmey J C; Shupnik M A; Veldhuis J D
Follicle-stimulating hormone increases concentrations of messenger ribonucleic acid encoding cytochrome P450 cholesterol side-chain cleavage enzyme in primary cultures of porcine granulosa cells.
Endocrinology 1991;128(4):2000-7.
1991: Nunley W C; Urban R J; Kitchin J D; Bateman B G; Evans W S; Veldhuis J D
Dynamics of pulsatile prolactin release during the postpartum lactational period.
The Journal of clinical endocrinology and metabolism 1991;72(2):287-93.
1991: Hartman M L; Faria A C; Vance M L; Johnson M L; Thorner M O; Veldhuis J D
Temporal structure of in vivo growth hormone secretory events in humans.
The American journal of physiology 1991;260(1 Pt 1):E101-10.
1991: Urban R J; Veldhuis J D
A selective serotonin reuptake inhibitor, fluoxetine hydrochloride, modulates the pulsatile release of prolactin in postmenopausal women.
American journal of obstetrics and gynecology 1991;164(1 Pt 1):147-52.
1991: Veldhuis J D; Iranmanesh A; Ho K K; Waters M J; Johnson M L; Lizarralde G
Dual defects in pulsatile growth hormone secretion and clearance subserve the hyposomatotropism of obesity in man.
The Journal of clinical endocrinology and metabolism 1991;72(1):51-9.
1991: Urban R J; Dahl K D; Padmanabhan V; Beitins I Z; Veldhuis J D
Specific regulatory actions of dihydrotestosterone and estradiol on the dynamics of FSH secretion and clearance in humans.
Journal of andrology 1991;12(1):27-35.
1991: Veldhuis J D; Johnson M L; Wilkowski M J; Iranmanesh A; Bolton W K
Neuroendocrine alterations in the somatotrophic axis in chronic renal failure.
Acta paediatrica Scandinavica. Supplement 1991;379():12-22; discussion 23.
1990: Sollenberger M J; Carlsen E C; Johnson M L; Veldhuis J D; Evans W S
Specific physiological regulation of luteinizing hormone secretory events throughout the human menstrual cycle: new insights into the pulsatile mode of gonadotropin release.
Journal of neuroendocrinology 1990;2(6):845-52.
1990: Veldhuis J D; Johnson M L
A Review and Appraisal of Deconvolution Methods to Evaluate in vivo Neuroendocrine Secretory Events.
Journal of neuroendocrinology 1990;2(6):755-71.
1990: Weltman J Y; Veldhuis J D; Weltman A; Kerrigan J R; Evans W S; Rogol A D
Reliability of estimates of pulsatile characteristics of luteinizing hormone and growth hormone release in women.
The Journal of clinical endocrinology and metabolism 1990;71(6):1646-52.
1990: Flores J A; Veldhuis J D; Leong D A
Follicle-stimulating hormone evokes an increase in intracellular free calcium ion concentrations in single ovarian (granulosa) cells.
Endocrinology 1990;127(6):3172-9.
1990: Veldhuis J D; Iranmanesh A; Johnson M L; Lizarralde G
Twenty-four-hour rhythms in plasma concentrations of adenohypophyseal hormones are generated by distinct amplitude and/or frequency modulation of underlying pituitary secretory bursts.
The Journal of clinical endocrinology and metabolism 1990;71(6):1616-23.
1990: Sollenberger M J; Carlsen E C; Booth R A; Johnson M L; Veldhuis J D; Evans W S
Nature of gonadotropin-releasing hormone self-priming of luteinizing hormone secretion during the normal menstrual cycle.
American journal of obstetrics and gynecology 1990;163(5 Pt 1):1529-34.
1990: Urban R J; Garmey J C; Shupnik M A; Veldhuis J D
Insulin-like growth factor type I increases concentrations of messenger ribonucleic acid encoding cytochrome P450 cholesterol side-chain cleavage enzyme in primary cultures of porcine granulosa cells.
Endocrinology 1990;127(5):2481-8.
1990: Iranmanesh A; Lizarralde G; Short D; Veldhuis J D
Intensive venous sampling paradigms disclose high frequency adrenocorticotropin release episodes in normal men.
The Journal of clinical endocrinology and metabolism 1990;71(5):1276-83.
1990: Veldhuis J D; Lassiter A E; Johnson M L
Operating behavior of dual or multiple endocrine pulse generators.
The American journal of physiology 1990;259(3 Pt 1):E351-61.
1990: Veldhuis J D
The hypothalamic pulse generator: the reproductive core.
Clinical obstetrics and gynecology 1990;33(3):538-50.
1990: Thorner M O; Vance M L; Hartman M L; Holl R W; Evans W S; Veldhuis J D; Van Cauter E; Copinschi G; Bowers C Y
Physiological role of somatostatin on growth hormone regulation in humans.
Metabolism: clinical and experimental 1990;39(9 Suppl 2):40-2.
1990: Veldhuis J D; Iranmanesh A; Johnson M L; Lizarralde G
Amplitude, but not frequency, modulation of adrenocorticotropin secretory bursts gives rise to the nyctohemeral rhythm of the corticotropic axis in man.
The Journal of clinical endocrinology and metabolism 1990;71(2):452-63.
1990: Weltman J Y; Seip R L; Weltman A; Snead D; Evans W S; Veldhuis J D; Rogol A D
Release of luteinizing hormone and growth hormone after recovery from maximal exercise.
Journal of applied physiology (Bethesda, Md. : 1985) 1990;69(1):196-200.
1990: Iranmanesh A; Veldhuis J D; Carlsen E C; Vaccaro V A; Booth R A; Lizarralde G; Asplin C M; Evans W S
Attenuated pulsatile release of prolactin in men with insulin-dependent diabetes mellitus.
The Journal of clinical endocrinology and metabolism 1990;71(1):73-8.
1990: Veldhuis J D; Johnson M L
An overview of computer algorithms for deconvolution-based assessment of in vivo neuroendocrine secretory events.
BioTechniques 1990;8(6):634-9.
1990: Hartman M L; Veldhuis J D; Vance M L; Faria A C; Furlanetto R W; Thorner M O
Somatotropin pulse frequency and basal concentrations are increased in acromegaly and are reduced by successful therapy.
The Journal of clinical endocrinology and metabolism 1990;70(5):1375-84.
1990: Urban R J; Veldhuis J D
Effects of short-term stimulation of serotoninergic pathways on the pulsatile secretion of luteinizing hormone in the absence and presence of acute opiate-receptor blockage.
Journal of andrology 1990;11(3):227-32.
1990: Urban R J; Pavlou S N; Rivier J E; Vale W W; Dufau M L; Veldhuis J D
Suppressive actions of a gonadotropin-releasing hormone antagonist on luteinizing hormone, follicle-stimulating hormone, and prolactin release in estrogen-deficient postmenopausal women.
American journal of obstetrics and gynecology 1990;162(5):1255-60.
1990: Veldhuis J D; Johnson M L; Iranmanesh A; Lizarralde G
Temporal structure of in vivo adrenal secretory activity estimated by deconvolution analysis.
Journal of biological rhythms 1990;5(3):247-55.
1990: Thorner M O; Vance M L; Rogol A D; Blizzard R M; Veldhuis J D; Cauter E V; Copinschi G; Bowers C Y
Growth hormone-releasing hormone and growth hormone-releasing peptide as potential therapeutic modalities.
Acta paediatrica Scandinavica. Supplement 1990;367():29-32.
1989: Veldhuis J D; Evans W S; Stumpf P G
Mechanisms that subserve estradiol's induction of increased prolactin concentrations: evidence of amplitude modulation of spontaneous prolactin secretory bursts.
American journal of obstetrics and gynecology 1989;161(5):1149-58.
1989: Wheeler M B; Veldhuis J D
Facilitative actions of the protein kinase-C effector system on hormonally stimulated adenosine 3',5'-monophosphate production by swine luteal cells.
Endocrinology 1989;125(5):2414-20.
1989: Veldhuis J D; Urban R J; Beitins I Z; Blizzard R M; Johnson M L; Dufau M L
Pathophysiological features of the pulsatile secretion of biologically active luteinizing hormone in man.
Journal of steroid biochemistry 1989;33(4B):739-49.
1989: Veldhuis J D
The estrogen-prolactinoma nexus in humans--fact or fable?
Mayo Clinic proceedings. Mayo Clinic 1989;64(9):1190-2.
1989: Martha P M; Rogol A D; Veldhuis J D; Kerrigan J R; Goodman D W; Blizzard R M
Alterations in the pulsatile properties of circulating growth hormone concentrations during puberty in boys.
The Journal of clinical endocrinology and metabolism 1989;69(3):563-70.
1989: Asplin C M; Faria A C; Carlsen E C; Vaccaro V A; Barr R E; Iranmanesh A; Lee M M; Veldhuis J D; Evans W S
Alterations in the pulsatile mode of growth hormone release in men and women with insulin-dependent diabetes mellitus.
The Journal of clinical endocrinology and metabolism 1989;69(2):239-45.
1989: Urban R J; Johnson M L; Veldhuis J D
Biophysical modeling of sensitivity and positive accuracy of detecting episodic endocrine signals.
The American journal of physiology 1989;257(1 Pt 1):E88-94.
1989: Veldhuis J D; Iranmanesh A; Lizarralde G; Johnson M L
Amplitude modulation of a burstlike mode of cortisol secretion subserves the circadian glucocorticoid rhythm.
The American journal of physiology 1989;257(1 Pt 1):E6-14.
1989: Veldhuis J D; Iranmanesh A; Clarke L; Kaiser D L; Johnson M L
Random and Non-Random Coincidence Between Luteinizing Hormone Peaks and Follicle-Stimulating Hormone, Alpha Subunit, Prolactin and Gonadotropin-Releasing Hormone ulsations.
Journal of neuroendocrinology 1989;1(3):185-94.
1989: Veldhuis J D; Gwynne J T
Insulin-like growth factor type I (somatomedin-C) stimulates high density lipoprotein (HDL) metabolism and HDL-supported progesterone biosynthesis by swine granulosa cells in vitro.
Endocrinology 1989;124(6):3069-76.
1989: Veldhuis J D; Demers L M
Mechanism(s) by which activation of protein kinase C is coupled to prostacyclin synthesis in granulosa cells.
Molecular and cellular endocrinology 1989;63(1-2):219-26.
1989: Urban R J; Johnson M L; Veldhuis J D
In vivo biological validation and biophysical modeling of the sensitivity and positive accuracy of endocrine peak detection. I. The LH pulse signal.
Endocrinology 1989;124(5):2541-7.
1989: Veldhuis J D; Winters S J
Nature of alpha subunit secretion in men: circadian rhythms, pulsatile release and secretory profiles.
Journal of andrology 1989;10(3):248-58.
1989: Veldhuis J D; O'Dea L S; Johnson M L
The nature of the gonadotropin-releasing hormone stimulus-luteinizing hormone secretory response of human gonadotrophs in vivo.
The Journal of clinical endocrinology and metabolism 1989;68(3):661-70.
1989: Faria A C; Veldhuis J D; Thorner M O; Vance M L
Half-time of endogenous growth hormone (GH) disappearance in normal man after stimulation of GH secretion by GH-releasing hormone and suppression with somatostatin.
The Journal of clinical endocrinology and metabolism 1989;68(3):535-41.
1989: Veldhuis J D; Johnson M L; Dufau M L
Physiological attributes of endogenous bioactive luteinizing hormone secretory bursts in man.
The American journal of physiology 1989;256(2 Pt 1):E199-207.
1989: Iranmanesh A; Veldhuis J D; Johnson M L; Lizarralde G
24-hour pulsatile and circadian patterns of cortisol secretion in alcoholic men.
Journal of andrology 1989;10(1):54-63.
1989: Wheeler M B; Veldhuis J D
Purification of three forms of chromatographically distinct protein kinase C from the swine ovary.
Molecular and cellular endocrinology 1989;61(1):117-22.
1988: Veldhuis J D; Johnson M L
A novel general biophysical model for simulating episodic endocrine gland signaling.
The American journal of physiology 1988;255(6 Pt 1):E749-59.
1988: Urban R J; Davis M R; Rogol A D; Johnson M L; Veldhuis J D
Acute androgen receptor blockade increases luteinizing hormone secretory activity in men.
The Journal of clinical endocrinology and metabolism 1988;67(6):1149-55.
1988: Veldhuis J D
Management of amenorrhea.
Hospital practice (Office ed.) 1988;23(11A):40-7, 50-2, 55-6.
1988: Wheeler M B; Veldhuis J D
Interactions of protein kinase C with receptor- and non-receptor-mediated cyclic AMP generation in swine granulosa cells.
Molecular and cellular endocrinology 1988;59(3):195-203.
1988: Veldhuis J D
Follicle-stimulating hormone regulates low density lipoprotein metabolism by swine granulosa cells.
Endocrinology 1988;123(3):1660-7.
1988: Veldhuis J D; Johnson M L
Operating characteristics of the hypothalamo-pituitary-gonadal axis in men: circadian, ultradian, and pulsatile release of prolactin and its temporal coupling with luteinizing hormone.
The Journal of clinical endocrinology and metabolism 1988;67(1):116-23.
1988: Veldhuis J D; Johnson M L
In vivo dynamics of luteinizing hormone secretion and clearance in man: assessment by deconvolution mechanics.
The Journal of clinical endocrinology and metabolism 1988;66(6):1291-300.
1988: Veldhuis J D; Rodgers R J; Hewlett E L
Actions of cyclic adenosine monophosphate on the cytodifferentiation of ovarian cells: studies in cultured swine granulosa cells using a novel exogenous adenylate cyclase from Bordetella pertussis.
Molecular endocrinology (Baltimore, Md.) 1988;2(6):499-506.
1988: Iranmanesh A; Veldhuis J D; Samojlik E; Rogol A D; Johnson M L; Lizarralde G
Alterations in the pulsatile properties of gonadotropin secretion in alcoholic men.
Journal of andrology 1988;9(3):207-14.
1988: Urban R J; Veldhuis J D; Blizzard R M; Dufau M L
Attenuated release of biologically active luteinizing hormone in healthy aging men.
The Journal of clinical investigation 1988;81(4):1020-9.
1988: Ho K Y; Veldhuis J D; Johnson M L; Furlanetto R; Evans W S; Alberti K G; Thorner M O
Fasting enhances growth hormone secretion and amplifies the complex rhythms of growth hormone secretion in man.
The Journal of clinical investigation 1988;81(4):968-75.
1988: Veldhuis J D; Evans W S; Urban R J; Rogol A D; Johnson M L
Physiologic attributes of the luteinizing hormone pulse signal in the human. Cross-validation studies in men.
Journal of andrology 1988;9(2):69-77.
1988: Veldhuis J D; Christiansen E; Evans W S; Kolp L A; Rogol A D; Johnson M L
Physiological profiles of episodic progesterone release during the midluteal phase of the human menstrual cycle: analysis of circadian and ultradian rhythms, discrete pulse properties, and correlations with simultaneous luteinizing hormone release.
The Journal of clinical endocrinology and metabolism 1988;66(2):414-21.
1988: Urban R J; Evans W S; Rogol A D; Kaiser D L; Johnson M L; Veldhuis J D
Contemporary aspects of discrete peak-detection algorithms. I. The paradigm of the luteinizing hormone pulse signal in men.
Endocrine reviews 1988;9(1):3-37.
1988: Urban R J; Kaiser D L; van Cauter E; Johnson M L; Veldhuis J D
Comparative assessments of objective peak-detection algorithms. II. Studies in men.
The American journal of physiology 1988;254(1 Pt 1):E113-9.
1988: Veldhuis J D; Faria A; Vance M L; Evans W S; Thorner M O; Johnson M L
Contemporary tools for the analysis of episodic growth hormone secretion and clearance in vivo.
Acta paediatrica Scandinavica. Supplement 1988;347():63-82.
1987: Veldhuis J D
Prostaglandin F2 alpha initiates polyphosphatidylinositol hydrolysis and membrane translocation of protein kinase C in swine ovarian cells.
Biochemical and biophysical research communications 1987;149(1):112-7.
1987: Veldhuis J D; King J C; Urban R J; Rogol A D; Evans W S; Kolp L A; Johnson M L
Operating characteristics of the male hypothalamo-pituitary-gonadal axis: pulsatile release of testosterone and follicle-stimulating hormone and their temporal coupling with luteinizing hormone.
The Journal of clinical endocrinology and metabolism 1987;65(5):929-41.
1987: Veldhuis J D; Carlson M L; Johnson M L
The pituitary gland secretes in bursts: appraising the nature of glandular secretory impulses by simultaneous multiple-parameter deconvolution of plasma hormone concentrations.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(21):7686-90.
1987: Veldhuis J D
Pathophysiologic features of episodic gonadotropin secretion in man.
The American journal of the medical sciences 1987;294(3):150-60.
1987: Veldhuis J D; Demers L M
Activation of protein kinase C is coupled to prostaglandin E2 synthesis in swine granulosa cells.
Prostaglandins 1987;33(6):819-29.

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