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Marlon Veldwijk

Research Profile

Chemicals & Drugs

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Gene Transfer Techniques

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Helen Hagen; Elmar Jentzsch; Paul Marzenell; Marlon R Veldwijk; Frederik Wenz; Andriy Mokhir
Aminoferrocene-based prodrugs activated by reactive oxygen species.
Marlon R Veldwijk; Meng Wang; W Jens Zeller; Stefan Fruehauf; Carsten Herskind; Patrick Maier; Julian Trah; Frederik Wenz
Overexpression of manganese superoxide dismutase does not increase clonogenic cell survival despite effect on apoptosis in irradiated lymphoblastoid cells.
Leopold Sellner; Marlon R Veldwijk; Jürgen A Kleinschmidt; Stephanie Laufs; Julian Topaly; Stefan Fruehauf; W Jens Zeller; Frederik Wenz
Efficient gene transfer with pseudotyped recombinant adeno-associated viral vectors into human chronic myelogenous leukemia cells.

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All Publications

2012: Helen Hagen; Elmar Jentzsch; Paul Marzenell; Marlon R Veldwijk; Frederik Wenz; Andriy Mokhir
Aminoferrocene-based prodrugs activated by reactive oxygen species.
Journal of medicinal chemistry 2012;55(2):924-34.
2011: Marlon R Veldwijk; Meng Wang; W Jens Zeller; Stefan Fruehauf; Carsten Herskind; Patrick Maier; Julian Trah; Frederik Wenz
Overexpression of manganese superoxide dismutase does not increase clonogenic cell survival despite effect on apoptosis in irradiated lymphoblastoid cells.
Radiation research 2011;176(6):725-31.
2011: Leopold Sellner; Marlon R Veldwijk; Jürgen A Kleinschmidt; Stephanie Laufs; Julian Topaly; Stefan Fruehauf; W Jens Zeller; Frederik Wenz
Efficient gene transfer with pseudotyped recombinant adeno-associated viral vectors into human chronic myelogenous leukemia cells.
Leukemia & lymphoma 2011;52(3):483-90.
2011: Doreen Heckmann; Stephanie Laufs; Patrick Maier; Marlon R Veldwijk; Frederik Wenz; W Jens Zeller; Manuela Zucknick; Volker Eckstein; Stefan Fruehauf; Frank A Giordano; Heike Allgayer
A Lentiviral CXCR4 overexpression and knockdown model in colorectal cancer cell lines reveals plerixafor-dependent suppression of SDF-1α-induced migration and invasion.
Onkologie 2011;34(10):502-8.
2010: P Maier; I Spier; Stephanie Laufs; Marlon R Veldwijk; Stefan Fruehauf; F Wenz; W Jens Zeller
Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O(6)-methylguanine-DNA methyltransferase(P140K).
Gene therapy 2010;17(3):389-99.
2010: Marlon R Veldwijk; Leopold Sellner; Marius Stiefelhagen; Jürgen A Kleinschmidt; Stephanie Laufs; Julian Topaly; Stefan Fruehauf; W Jens Zeller; Frederik Wenz
Pseudotyped recombinant adeno-associated viral vectors mediate efficient gene transfer into primary human CD34(+) peripheral blood progenitor cells.
Cytotherapy 2010;12(1):107-12.
2009: Falk Dillmann; Marlon R Veldwijk; Stephanie Laufs; Markus Sperandio; Gary Calandra; Frederik Wenz; Jens Zeller; Stefan Fruehauf
Plerixafor inhibits chemotaxis toward SDF-1 and CXCR4-mediated stroma contact in a dose-dependent manner resulting in increased susceptibility of BCR-ABL+ cell to Imatinib and Nilotinib.
Leukemia & lymphoma 2009;50(10):1676-86.
2009: Marlon R Veldwijk; Carsten Herskind; Leopold Sellner; Aleksandar Radujkovic; Stephanie Laufs; Stefan Fruehauf; W Jens Zeller; Frederik Wenz
Normal-tissue radioprotection by overexpression of the copper-zinc and manganese superoxide dismutase genes.
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 2009;185(8):517-23.
2009: Stefan Fruehauf; Marlon R Veldwijk; Timon Seeger; Mario Schubert; Stephanie Laufs; Julian Topaly; Patrick Wuchter; Falk Dillmann; Volker Eckstein; Frederik Wenz; Hartmut Goldschmidt; Anthony Dick Ho; Gary Calandra
A combination of granulocyte-colony-stimulating factor (G-CSF) and plerixafor mobilizes more primitive peripheral blood progenitor cells than G-CSF alone: results of a European phase II study.
Cytotherapy 2009;11(8):992-1001.
2008: Leopold Sellner; Marius Stiefelhagen; Jürgen A Kleinschmidt; Stephanie Laufs; Frederik Wenz; Stefan Fruehauf; W Jens Zeller; Marlon R Veldwijk
Generation of efficient human blood progenitor-targeted recombinant adeno-associated viral vectors (AAV) by applying an AAV random peptide library on primary human hematopoietic progenitor cells.
Experimental hematology 2008;36(8):957-64.
2008: Marlon R Veldwijk; Simone Berlinghoff; Anna Jauch; Stephanie Laufs; W Jens Zeller; Frederik Wenz; Stefan Fruehauf
Characterization of human mesothelioma cell lines as tumor models for suicide gene therapy.
Onkologie 2008;31(3):91-6.
2008: Marius Stiefelhagen; Leopold Sellner; Jürgen A Kleinschmidt; Anna Jauch; Stephanie Laufs; Frederik Wenz; W Jens Zeller; Stefan Fruehauf; Marlon R Veldwijk
Application of a haematopoetic progenitor cell-targeted adeno-associated viral (AAV) vector established by selection of an AAV random peptide library on a leukaemia cell line.
Genetic vaccines and therapy 2008;6():12.
2007: Daniel Ribeiro; Marlon R Veldwijk; Axel Benner; Stephanie Laufs; Frederik Wenz; Anthony Ho; Stefan Fruehauf
Differences in functional activity and antigen expression of granulocytes primed in vivo with filgrastim, lenograstim, or pegfilgrastim.
Transfusion 2007;47(6):969-80.
2007: Stefan Fruehauf; Jens Klaus; Johannes Huesing; Marlon R Veldwijk; Eike C Buss; Julian Topaly; Timon Seeger; L W J Zeller; Thomas Moehler; Anthony Ho; Hartmut Goldschmidt
Efficient mobilization of peripheral blood stem cells following CAD chemotherapy and a single dose of pegylated G-CSF in patients with multiple myeloma.
Bone marrow transplantation 2007;39(12):743-50.
2005: A Radujkovic; Moritz Schad; Julian Topaly; Marlon R Veldwijk; Stephanie Laufs; B S Schultheis; Anna Jauch; Junia V Melo; Stefan Fruehauf; W Jens Zeller
Synergistic activity of imatinib and 17-AAG in imatinib-resistant CML cells overexpressing BCR-ABL--Inhibition of P-glycoprotein function by 17-AAG.
Leukemia 2005;19(7):1198-206.
2004: Simone Berlinghoff; Marlon R Veldwijk; Stephanie Laufs; Hans-Peter Maser; Anna Jauch; Frederik Wenz; W Jens Zeller; Stefan Fruehauf
Susceptibility of mesothelioma cell lines to adeno-associated virus 2 vector-based suicide gene therapy.
Lung cancer (Amsterdam, Netherlands) 2004;46(2):179-86.
2004: Marlon R Veldwijk; Carsten Herskind; Stephanie Laufs; W Jens Zeller; Stefan Fruehauf; Frederik Wenz
Recombinant adeno-associated virus 2-mediated transfer of the human superoxide-dismutase gene does not confer radioresistance on HeLa cervical carcinoma cells.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2004;72(3):341-50.
2004: Marlon R Veldwijk; Simone Berlinghoff; Stephanie Laufs; Ulrich R Hengge; W Jens Zeller; Frederik Wenz; Stefan Fruehauf
Suicide gene therapy of sarcoma cell lines using recombinant adeno-associated virus 2 vectors.
Cancer gene therapy 2004;11(8):577-84.
2003: Stefan Fruehauf; Marlon R Veldwijk; W Jens Zeller; Stephanie Laufs
Prospects and RISC score of viral gene therapy for sarcoma.
Expert opinion on biological therapy 2003;3(8):1241-51.
2003: Stefan Fruehauf; Julian Topaly; Matthias Villalobos; Marlon R Veldwijk; Stephanie Laufs; Anthony Ho
Quantitative real-time polymerase chain reaction shows that treatment with interferon reduces the initially upregulated PRV-1 expression in polycythemia vera patients.
Haematologica 2003;88(3):349-51.
2002: Marlon R Veldwijk; Julian Topaly; Stephanie Laufs; Ulrich R Hengge; Frederik Wenz; W Jens Zeller; Stefan Fruehauf
Development and optimization of a real-time quantitative PCR-based method for the titration of AAV-2 vector stocks.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(2):272-8.
2002: Stefan Fruehauf; Marlon R Veldwijk; Simone Berlinghoff; N Basara; C Baum; M Flasshove; S Hegewisch-Becker; N Kröger; T Licht; T Moritz; Ulrich R Hengge; W Jens Zeller; Stephanie Laufs
Gene therapy for sarcoma.
Cells, tissues, organs 2002;172(2):133-44.
2000: Marlon R Veldwijk; Stefan Fruehauf; Bernhard Schiedlmeier; Jürgen A Kleinschmidt; W Jens Zeller
Differential expression of a recombinant adeno-associated virus 2 vector in human CD34+ cells and breast cancer cells.
Cancer gene therapy 2000;7(4):597-604.
1999: Marlon R Veldwijk; Bernhard Schiedlmeier; Jürgen A Kleinschmidt; W Jens Zeller; Stefan Fruehauf
Superior gene transfer into solid tumour cells than into human mobilised peripheral blood progenitor cells using helpervirus-free adeno-associated viral vector stocks.
European journal of cancer (Oxford, England : 1990) 1999;35(7):1136-42.
1999: Bernhard Schiedlmeier; Eike C Buss; Marlon R Veldwijk; W Jens Zeller; Stefan Fruehauf
Soluble bone marrow stroma factors improve the efficiency of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells.
Human gene therapy 1999;10(9):1443-52.
1999: Stefan Fruehauf; K Schmitt; Marlon R Veldwijk; Julian Topaly; Axel Benner; W Jens Zeller; Anthony Ho; Rainer Haas
Peripheral blood progenitor cell (PBPC) counts during steady-state haemopoiesis enable the estimation of the yield of mobilized PBPC after granulocyte colony-stimulating factor supported cytotoxic chemotherapy: an update on 100 patients.
British journal of haematology 1999;105(3):786-94.
1998: Stefan Fruehauf; Marlon R Veldwijk; A Krämer; Rainer Haas; W Jens Zeller
Delineation of cell cycle state and correlation to adhesion molecule expression of human CD34+ cells from steady-state bone marrow and peripheral blood mobilized following G-CSF-supported chemotherapy.
Stem cells (Dayton, Ohio) 1998;16(4):271-9.
1998: Stefan Fruehauf; K Wermann; Eike C Buss; P Hundsdoerfer; Marlon R Veldwijk; Rainer Haas; W Jens Zeller
Protection of hematopoietic stem cells from chemotherapy-induced toxicity by multidrug-resistance 1 gene transfer.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1998;144():93-115.