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Gerard Venema

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Gene Expression Regulation, Bacterial

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Anton Steen; Girbe Buist; Naomi E Kramer; Ruud Jalving; Germaine F J D Benus; Gerard Venema; Oscar P Kuipers; Jan Kok
Reduced lysis upon growth of Lactococcus lactis on galactose is a consequence of decreased binding of the autolysin AcmA.
Erwin H Duitman; Dobek ( Dobroslaw ) Wyczawski; Ludolf G Boven; Gerard Venema; Oscar P Kuipers; Leendert W Hamoen
Novel methods for genetic transformation of natural Bacillus subtilis isolates used to study the regulation of the mycosubtilin and surfactin synthetases.
R Ramasamy; SG Yasawardena; Aldert L Zomer; Gerard Venema; Jan Kok; Kees Leenhouts
Immunogenicity of a malaria parasite antigen displayed by Lactococcus lactis in oral immunisations.

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2008: Anton Steen; Girbe Buist; Naomi E Kramer; Ruud Jalving; Germaine F J D Benus; Gerard Venema; Oscar P Kuipers; Jan Kok
Reduced lysis upon growth of Lactococcus lactis on galactose is a consequence of decreased binding of the autolysin AcmA.
Applied and environmental microbiology 2008;74(15):4671-9.
2007: Erwin H Duitman; Dobek ( Dobroslaw ) Wyczawski; Ludolf G Boven; Gerard Venema; Oscar P Kuipers; Leendert W Hamoen
Novel methods for genetic transformation of natural Bacillus subtilis isolates used to study the regulation of the mycosubtilin and surfactin synthetases.
Applied and environmental microbiology 2007;73(11):3490-6.
2006: R Ramasamy; SG Yasawardena; Aldert L Zomer; Gerard Venema; Jan Kok; Kees Leenhouts
Immunogenicity of a malaria parasite antigen displayed by Lactococcus lactis in oral immunisations.
Vaccine 2006;24(18):3900-8.
2006: John G Kenny; Stephen Leach; Ana Belén de la Hoz; Gerard Venema; Jan Kok; Gerald F Fitzgerald; Arjen Nauta; Juan C Alonso; Douwe van Sinderen
Characterization of the lytic-lysogenic switch of the lactococcal bacteriophage Tuc2009.
Virology 2006;347(2):434-46.
2005: Anton Steen; Girbe Buist; Gavin J Horsburgh; Gerard Venema; Oscar P Kuipers; Simon J Foster; Jan Kok
AcmA of Lactococcus lactis is an N-acetylglucosaminidase with an optimal number of LysM domains for proper functioning.
The FEBS journal 2005;272(11):2854-68.
2004: Kim A Susanna; A F van der Werff; Chris D den Hengst; B Calles; M Salas; Gerard Venema; Leendert W Hamoen; Oscar P Kuipers
Mechanism of transcription activation at the comG promoter by the competence transcription factor ComK of Bacillus subtilis.
Journal of bacteriology 2004;186(4):1120-8.
2003: Anton Steen; Girbe Buist; Kees Leenhouts; Mohamed El Khattabi; Froukje Grijpstra; Aldert L Zomer; Gerard Venema; Oscar P Kuipers; Jan Kok
Cell wall attachment of a widely distributed peptidoglycan binding domain is hindered by cell wall constituents.
The Journal of biological chemistry 2003;278(26):23874-81.
2003: Roelke Venema; Harold Tjalsma; Jan Maarten van Dijl; Anne de Jong; Kees Leenhouts; Girbe Buist; Gerard Venema
Active lipoprotein precursors in the Gram-positive eubacterium Lactococcus lactis.
The Journal of biological chemistry 2003;278(17):14739-46.
2003: Leendert W Hamoen; Daisy Kausche; Mohamed A Marahiel; Douwe van Sinderen; Gerard Venema; Pascale Serror
The Bacillus subtilis transition state regulator AbrB binds to the -35 promoter region of comK.
FEMS microbiology letters 2003;218(2):299-304.
2003: Leendert W Hamoen; Gerard Venema; Oscar P Kuipers
Controlling competence in Bacillus subtilis: shared use of regulators.
Microbiology (Reading, England) 2003;149(Pt 1):9-17.
2002: Manuel Zúñiga; Blandine Franke-Fayard; Gerard Venema; Jan Kok; Arjen Nauta
Characterization of the putative replisome organizer of the lactococcal bacteriophage r1t.
Journal of virology 2002;76(20):10234-44.
2002: Arno de Kreij; Bertus van den Burg; Gerard Venema; Gert Vriend; Vincent G H Eijsink; Jens Nielsen
The effects of modifying the surface charge on the catalytic activity of a thermolysin-like protease.
The Journal of biological chemistry 2002;277(18):15432-8.
2001: Leendert W Hamoen; BJ Haijema; J J Bijlsma; Gerard Venema; C M Lovett
The Bacillus subtilis competence transcription factor, ComK, overrides LexA-imposed transcriptional inhibition without physically displacing LexA.
The Journal of biological chemistry 2001;276(46):42901-7.
2001: Arno de Kreij; Bertus van den Burg; OR Veltman; Gert Vriend; Gerard Venema; Vincent G H Eijsink
The effect of changing the hydrophobic S1' subsite of thermolysin-like proteases on substrate specificity.
European journal of biochemistry / FEBS 2001;268(18):4985-91.
2001: Maarten L van Roosmalen; Jan D H Jongbloed; Jean-Yves François Dubois; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
Distinction between major and minor Bacillus signal peptidases based on phylogenetic and structural criteria.
The Journal of biological chemistry 2001;276(27):25230-5.
2001: Maarten L van Roosmalen; Jan D H Jongbloed; A de Jonf; J van Eerden; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
Detergent-independent in vitro activity of a truncated Bacillus signal peptidase.
Microbiology (Reading, England) 2001;147(Pt 4):909-17.
2001: PA Risøen; Ola Johnsborg; Dzung B Diep; Leendert W Hamoen; Gerard Venema; Ingolf F Nes
Regulation of bacteriocin production in Lactobacillus plantarum depends on a conserved promoter arrangement with consensus binding sequence.
Molecular genetics and genomics : MGG 2001;265(1):198-206.
2000: Jan D H Jongbloed; U Martin; Haike Antelmann; Michael Hecker; Harold Tjalsma; Gerard Venema; Sierd Bron; Jan Maarten van Dijl; J Müller
TatC is a specificity determinant for protein secretion via the twin-arginine translocation pathway.
The Journal of biological chemistry 2000;275(52):41350-7.
2000: Arno de Kreij; Gerard Venema; Bertus van den Burg
Substrate specificity in the highly heterogeneous M4 peptidase family is determined by a small subset of amino acids.
The Journal of biological chemistry 2000;275(40):31115-20.
2000: Maarten L van Roosmalen; Jan D H Jongbloed; Anneke Kuipers; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
A truncated soluble Bacillus signal peptidase produced in Escherichia coli is subject to self-cleavage at its active site.
Journal of bacteriology 2000;182(20):5765-70.
2000: Harold Tjalsma; A G Stover; A Driks; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
Conserved serine and histidine residues are critical for activity of the ER-type signal peptidase SipW of Bacillus subtilis.
The Journal of biological chemistry 2000;275(33):25102-8.
2000: Leendert W Hamoen; A F Van Werkhoven; Gerard Venema; David Dubnau
The pleiotropic response regulator DegU functions as a priming protein in competence development in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(16):9246-51.
1999: Erwin H Duitman; Leendert W Hamoen; M Rembold; Gerard Venema; H Seitz; Wolfram Saenger; Frank Bernhard; R Reinhardt; Marion Schmidt; C Ullrich; Torsten Stein; F Leenders; Joachim Vater
The mycosubtilin synthetase of Bacillus subtilis ATCC6633: a multifunctional hybrid between a peptide synthetase, an amino transferase, and a fatty acid synthase.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(23):13294-9.
1999: Harold Tjalsma; Geeske Zanen; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
The potential active site of the lipoprotein-specific (type II) signal peptidase of Bacillus subtilis.
The Journal of biological chemistry 1999;274(40):28191-7.
1999: Albert Bolhuis; A Matzen; Hanne-Leena Hyyryläinen; Vesa P Kontinen; Rob Meima; J Chapuis; Gerard Venema; Sierd Bron; Roland Freudl; Jan Maarten van Dijl
Signal peptide peptidase- and ClpP-like proteins of Bacillus subtilis required for efficient translocation and processing of secretory proteins.
The Journal of biological chemistry 1999;274(35):24585-92.
1999: Albert Bolhuis; Gerard Venema; Wim J Quax; Sierd Bron; Jan Maarten van Dijl
Functional analysis of paralogous thiol-disulfide oxidoreductases in Bacillus subtilis.
The Journal of biological chemistry 1999;274(35):24531-8.
1999: Bertus van den Burg; Arno de Kreij; P Van der Veek; Johanna Mansfeld; Gerard Venema
Characterization of a novel stable biocatalyst obtained by protein engineering.
Biotechnology and applied biochemistry 1999;30 ( Pt 1)():35-40.
1999: Gerard Venema; Jan Kok; Douwe van Sinderen
From DNA sequence to application: possibilities and complications.
Antonie van Leeuwenhoek 1999;76(1-4):3-23.
1999: Albert Bolhuis; Harold Tjalsma; H E Smith; Anne de Jong; Rob Meima; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
Evaluation of bottlenecks in the late stages of protein secretion in Bacillus subtilis.
Applied and environmental microbiology 1999;65(7):2934-41.
1999: Albert Bolhuis; Harold Tjalsma; Keith Stephenson; Colin R Harwood; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
Different mechanisms for thermal inactivation of Bacillus subtilis signal peptidase mutants.
The Journal of biological chemistry 1999;274(22):15865-8.
1999: Harold Tjalsma; J van den Dolder; W J Meijer; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
The plasmid-encoded signal peptidase SipP can functionally replace the major signal peptidases SipS and SipT of Bacillus subtilis.
Journal of bacteriology 1999;181(8):2448-54.
1999: C M Franke; J Tiemersma; Gerard Venema; Jan Kok
Membrane topology of the lactococcal bacteriocin ATP-binding cassette transporter protein LcnC. Involvement of LcnC in lactococcin a maturation.
The Journal of biological chemistry 1999;274(13):8484-90.
1999: Harold Tjalsma; Vesa P Kontinen; Zoltán Prágai; H Wu; Rob Meima; Gerard Venema; Sierd Bron; Matti Sarvas; Jan Maarten van Dijl
The role of lipoprotein processing by signal peptidase II in the Gram-positive eubacterium bacillus subtilis. Signal peptidase II is required for the efficient secretion of alpha-amylase, a non-lipoprotein.
The Journal of biological chemistry 1999;274(3):1698-707.
1998: Gert Vriend; H J Berendsen; Bertus van den Burg; Gerard Venema; Vincent G H Eijsink
Early steps in the unfolding of thermolysin-like proteases.
The Journal of biological chemistry 1998;273(52):35074-7.
1998: Kees Leenhouts; Albert Bolhuis; J Boot; I Deutz; M Toonen; Gerard Venema; Jan Kok; A Ledeboer
Cloning, expression, and chromosomal stabilization of the Propionibacterium shermanii proline iminopeptidase gene (pip) for food-grade application in Lactococcus lactis.
Applied and environmental microbiology 1998;64(12):4736-42.
1998: Girbe Buist; Gerard Venema; Jan Kok
Autolysis of Lactococcus lactis is influenced by proteolysis.
Journal of bacteriology 1998;180(22):5947-53.
1998: Sierd Bron; Albert Bolhuis; Harold Tjalsma; Siger Holsappel; Gerard Venema; Jan Maarten van Dijl
Protein secretion and possible roles for multiple signal peptidases for precursor processing in bacilli.
Journal of biotechnology 1998;64(1):3-13.
1998: Albert Bolhuis; Kees Broekhuizen; Alexei Sorokin; Maarten L van Roosmalen; Gerard Venema; Sierd Bron; Wim J Quax; Jan Maarten van Dijl
SecDF of Bacillus subtilis, a molecular Siamese twin required for the efficient secretion of proteins.
The Journal of biological chemistry 1998;273(33):21217-24.
1998: Harold Tjalsma; Albert Bolhuis; Maarten L van Roosmalen; Thomas Wiegert; W Schumann; Kees Broekhuizen; Wim J Quax; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
Functional analysis of the secretory precursor processing machinery of Bacillus subtilis: identification of a eubacterial homolog of archaeal and eukaryotic signal peptidases.
Genes & development 1998;12(15):2318-31.
1998: Leendert W Hamoen; A F Van Werkhoven; J J Bijlsma; David Dubnau; Gerard Venema
The competence transcription factor of Bacillus subtilis recognizes short A/T-rich sequences arranged in a unique, flexible pattern along the DNA helix.
Genes & development 1998;12(10):1539-50.
1998: Rob Meima; Gert Jan Haan; Gerard Venema; Sierd Bron; S de Jong
Sequence specificity of illegitimate plasmid recombination in Bacillus subtilis: possible recognition sites for DNA topoisomerase I.
Nucleic acids research 1998;26(10):2366-73.
1998: OR Veltman; Gert Vriend; H J Berendsen; Bertus van den Burg; Gerard Venema; Vincent G H Eijsink
A single calcium binding site is crucial for the calcium-dependent thermal stability of thermolysin-like proteases.
Biochemistry 1998;37(15):5312-9.
1998: OR Veltman; Vincent G H Eijsink; Gert Vriend; Arno de Kreij; Gerard Venema; Bertus van den Burg
Probing catalytic hinge bending motions in thermolysin-like proteases by glycine --> alanine mutations.
Biochemistry 1998;37(15):5305-11.
1998: Kees Leenhouts; Albert Bolhuis; Gerard Venema; Jan Kok
Construction of a food-grade multiple-copy integration system for Lactococcus lactis.
Applied microbiology and biotechnology 1998;49(4):417-23.
1998: JW Sanders; Gerard Venema; Jan Kok; Kees Leenhouts
Identification of a sodium chloride-regulated promoter in Lactococcus lactis by single-copy chromosomal fusion with a reporter gene.
Molecular & general genetics : MGG 1998;257(6):681-5.
1998: MA Noback; Siger Holsappel; Rense Kiewiet; Peter Terpstra; R Wambutt; Holger Wedler; Gerard Venema; Sierd Bron
The 172 kb prkA-addAB region from 83 degrees to 97 degrees of the Bacillus subtilis chromosome contains several dysfunctional genes, the glyB marker, many genes encoding transporter proteins, and the ubiquitous hit gene.
Microbiology (Reading, England) 1998;144 ( Pt 4)():859-75.
1998: Bertus van den Burg; Vincent G H Eijsink; Gert Vriend; OR Veltman; Gerard Venema
Rendering one autolysis site in Bacillus subtilis neutral protease resistant to cleavage reveals a new fission.
Biotechnology and applied biochemistry 1998;27 ( Pt 2)():125-32.
1998: Bertus van den Burg; Gert Vriend; OR Veltman; Gerard Venema; Vincent G H Eijsink
Engineering an enzyme to resist boiling.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2056-60.
1998: M L Callegari; B Riboli; JW Sanders; Pier Sandro Cocconcelli; Jan Kok; Gerard Venema; L Morelli
The S-layer gene of Lactobacillus helveticus CNRZ 892: cloning, sequence and heterologous expression.
Microbiology (Reading, England) 1998;144 ( Pt 3)():719-26.
1998: W J Meijer; G B Wisman; Peter Terpstra; P B Thorsted; C M Thomas; Siger Holsappel; Gerard Venema; Sierd Bron
Rolling-circle plasmids from Bacillus subtilis: complete nucleotide sequences and analyses of genes of pTA1015, pTA1040, pTA1050 and pTA1060, and comparisons with related plasmids from gram-positive bacteria.
FEMS microbiology reviews 1998;21(4):337-68.
1998: JW Sanders; Kees Leenhouts; J Burghoorn; J R Brands; Gerard Venema; Jan Kok
A chloride-inducible acid resistance mechanism in Lactococcus lactis and its regulation.
Molecular microbiology 1998;27(2):299-310.
1997: JW Sanders; Gerard Venema; Jan Kok
A chloride-inducible gene expression cassette and its use in induced lysis of Lactococcus lactis.
Applied and environmental microbiology 1997;63(12):4877-82.
1997: Harold Tjalsma; MA Noback; Sierd Bron; Gerard Venema; K Yamane; Jan Maarten van Dijl
Bacillus subtilis contains four closely related type I signal peptidases with overlapping substrate specificities. Constitutive and temporally controlled expression of different sip genes.
The Journal of biological chemistry 1997;272(41):25983-92.
1997: Arjen Nauta; Bertus van den Burg; Harma A Karsens; Gerard Venema; Jan Kok
Design of thermolabile bacteriophage repressor mutants by comparative molecular modeling.
Nature biotechnology 1997;15(10):980-3.
1997: OR Veltman; Gert Vriend; F Hardy; Johanna Mansfeld; Bertus van den Burg; Gerard Venema; Vincent G H Eijsink
Mutational analysis of a surface area that is critical for the thermal stability of thermolysin-like proteases.
European journal of biochemistry / FEBS 1997;248(2):433-40.
1997: Girbe Buist; Harma A Karsens; Arjen Nauta; Douwe van Sinderen; Gerard Venema; Jan Kok
Autolysis of Lactococcus lactis caused by induced overproduction of its major autolysin, AcmA.
Applied and environmental microbiology 1997;63(7):2722-8.
1997: M A Hellendoorn; Blandine Franke-Fayard; Igor Mierau; Gerard Venema; Jan Kok
Cloning and analysis of the pepV dipeptidase gene of Lactococcus lactis MG1363.
Journal of bacteriology 1997;179(11):3410-5.
1997: Johanna Mansfeld; Gert Vriend; B W Dijkstra; OR Veltman; Bertus van den Burg; Gerard Venema; Renate Ulbrich-Hofmann; Vincent G H Eijsink
Extreme stabilization of a thermolysin-like protease by an engineered disulfide bond.
The Journal of biological chemistry 1997;272(17):11152-6.
1997: Zoltán Prágai; Harold Tjalsma; Albert Bolhuis; Jan Maarten van Dijl; Gerard Venema; Sierd Bron
The signal peptidase II (Isp) gene of Bacillus subtilis.
Microbiology (Reading, England) 1997;143 ( Pt 4)():1327-33.
1997: OR Veltman; Gert Vriend; Bertus van den Burg; F Hardy; Gerard Venema; Vincent G H Eijsink
Engineering thermolysin-like proteases whose stability is largely independent of calcium.
FEBS letters 1997;405(2):241-4.
1997: A Elsner; H Engert; Wolfram Saenger; Leendert W Hamoen; Gerard Venema; Frank Bernhard
Substrate specificity of hybrid modules from peptide synthetases.
The Journal of biological chemistry 1997;272(8):4814-9.
1997: Rob Meima; BJ Haijema; H Dijkstra; Gert Jan Haan; Gerard Venema; Sierd Bron
Role of enzymes of homologous recombination in illegitimate plasmid recombination in Bacillus subtilis.
Journal of bacteriology 1997;179(4):1219-29.
1997: Igor Mierau; ER Kunji; Gerard Venema; Jan Kok
Casein and peptide degradation in lactic acid bacteria.
Biotechnology & genetic engineering reviews 1997;14():279-301.
1997: J Kooistra; BJ Haijema; A Hesseling-Meinders; Gerard Venema
A conserved helicase motif of the AddA subunit of the Bacillus subtilis ATP-dependent nuclease (AddAB) is essential for DNA repair and recombination.
Molecular microbiology 1997;23(1):137-49.
1997: K Turgay; Leendert W Hamoen; Gerard Venema; David Dubnau
Biochemical characterization of a molecular switch involving the heat shock protein ClpC, which controls the activity of ComK, the competence transcription factor of Bacillus subtilis.
Genes & development 1997;11(1):119-28.
1996: OR Veltman; Gert Vriend; Pieter Middelhoven; Bertus van den Burg; Gerard Venema; Vincent G H Eijsink
Analysis of structural determinants of the stability of thermolysin-like proteases by molecular modelling and site-directed mutagenesis.
Protein engineering 1996;9(12):1181-9.
1996: Kees Leenhouts; Girbe Buist; Albert Bolhuis; A ten Berge; J Kiel; Igor Mierau; M Dabrowska; Gerard Venema; Jan Kok
A general system for generating unlabelled gene replacements in bacterial chromosomes.
Molecular & general genetics : MGG 1996;253(1-2):217-24.
1996: M A Noback; Peter Terpstra; Siger Holsappel; Gerard Venema; Sierd Bron
A 22 kb DNA sequence in the cspB-glpPFKD region at 75 degrees on the Bacillus subtilis chromosome.
Microbiology (Reading, England) 1996;142 ( Pt 11)():3021-6.
1996: Albert Bolhuis; Alexei Sorokin; V Azevedo; S Dusko Ehrlich; P G Braun; A de Jong; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
Bacillus subtilis can modulate its capacity and specificity for protein secretion through temporally controlled expression of the sipS gene for signal peptidase I.
Molecular microbiology 1996;22(4):605-18.
1996: B J Haijema; Douwe van Sinderen; K Winterling; J Kooistra; Gerard Venema; Leendert W Hamoen
Regulated expression of the dinR and recA genes during competence development and SOS induction in Bacillus subtilis.
Molecular microbiology 1996;22(1):75-85.
1996: K Venema; M H Dost; Gerard Venema; Jan Kok
Mutational analysis and chemical modification of Cys24 of lactococcin B, a bacteriocin produced by Lactococcus lactis.
Microbiology (Reading, England) 1996;142 ( Pt 10)():2825-30.
1996: B J Haijema; M Noback; A Hesseling; J Kooistra; Gerard Venema; Rob Meima
Replacement of the lysine residue in the consensus ATP-binding sequence of the AddA subunit of AddAB drastically affects chromosomal recombination in transformation and transduction of Bacillus subtilis.
Molecular microbiology 1996;21(5):989-99.
1996: C Cordes; Rob Meima; B Twiest; B Kazemier; Gerard Venema; Jan Maarten van Dijl; Sierd Bron
The expression of a plasmid-specified exported protein causes structural plasmid instability in Bacillus subtilis.
Journal of bacteriology 1996;178(17):5235-42.
1996: B J Haijema; Rob Meima; J Kooistra; Gerard Venema
Effects of lysine-to-glycine mutations in the ATP-binding consensus sequences in the AddA and AddB subunits on the Bacillus subtilis AddAB enzyme activities.
Journal of bacteriology 1996;178(17):5130-7.
1996: B J Haijema; Gerard Venema; J Kooistra
The C terminus of the AddA subunit of the Bacillus subtilis ATP-dependent DNase is required for the ATP-dependent exonuclease activity but not for the helicase activity.
Journal of bacteriology 1996;178(17):5086-91.
1996: ER Kunji; Igor Mierau; Bert Poolman; Wil N Konings; Gerard Venema; Jan Kok
Fate of peptides in peptidase mutants of Lactococcus lactis.
Molecular microbiology 1996;21(1):123-31.
1996: K Venema; M H Dost; P A Beun; A J Haandrikman; Gerard Venema; Jan Kok
The genes for secretion and maturation of lactococcins are located on the chromosome of Lactococcus lactis IL1403.
Applied and environmental microbiology 1996;62(5):1689-92.
1996: Igor Mierau; ER Kunji; Kees Leenhouts; M A Hellendoorn; A J Haandrikman; Bert Poolman; Wil N Konings; Gerard Venema; Jan Kok
Multiple-peptidase mutants of Lactococcus lactis are severely impaired in their ability to grow in milk.
Journal of bacteriology 1996;178(10):2794-803.
1996: Douwe van Sinderen; Harma A Karsens; Jan Kok; Peter Terpstra; M H Ruiters; Gerard Venema; Arjen Nauta
Sequence analysis and molecular characterization of the temperate lactococcal bacteriophage r1t.
Molecular microbiology 1996;19(6):1343-55.
1996: Arjen Nauta; Douwe van Sinderen; Harma A Karsens; E Smit; Gerard Venema; Jan Kok
Inducible gene expression mediated by a repressor-operator system isolated from Lactococcus lactis bacteriophage r1t.
Molecular microbiology 1996;19(6):1331-41.
1996: W J Meijer; M Smith; R G Wake; A L de Boer; Gerard Venema; Sierd Bron
Identification and characterization of a novel type of replication terminator with bidirectional activity on the Bacillus subtilis theta plasmid pLS20.
Molecular microbiology 1996;19(6):1295-306.
1996: C M Franke; Kees Leenhouts; A J Haandrikman; Jan Kok; Gerard Venema; K Venema
Topology of LcnD, a protein implicated in the transport of bacteriocins from Lactococcus lactis.
Journal of bacteriology 1996;178(6):1766-9.
1996: Rob Meima; Gerard Venema; Sierd Bron
A positive selection vector for the analysis of structural plasmid instability in Bacillus subtilis.
Plasmid 1996;35(1):14-30.
1995: Jan A K W Kiel; A M ten Berge; Peter Borger; Gerard Venema
A general method for the consecutive integration of single copies of a heterologous gene at multiple locations in the Bacillus subtilis chromosome by replacement recombination.
Applied and environmental microbiology 1995;61(12):4244-50.
1995: J Law; Girbe Buist; A Haandrikman; Jan Kok; Gerard Venema; Kees Leenhouts
A system to generate chromosomal mutations in Lactococcus lactis which allows fast analysis of targeted genes.
Journal of bacteriology 1995;177(24):7011-8.
1995: Jos Seegers; A C Zhao; W J Meijer; S A Khan; Gerard Venema; Sierd Bron
Structural and functional analysis of the single-strand origin of replication from the lactococcal plasmid pWV01.
Molecular & general genetics : MGG 1995;249(1):43-50.
1995: JW Sanders; Kees Leenhouts; A J Haandrikman; Gerard Venema; Jan Kok
Stress response in Lactococcus lactis: cloning, expression analysis, and mutation of the lactococcal superoxide dismutase gene.
Journal of bacteriology 1995;177(18):5254-60.
1995: Michael Chikindas; K Venema; A M Ledeboer; Gerard Venema; Jan Kok
Expression of lactococcin A and pediocin PA-1 in heterologous hosts.
Letters in applied microbiology 1995;21(3):183-9.
1995: Rob Meima; B J Haijema; Gerard Venema; Sierd Bron
Overproduction of the ATP-dependent nuclease AddAB improves the structural stability of a model plasmid system in Bacillus subtilis.
Molecular & general genetics : MGG 1995;248(4):391-8.
1995: W J Meijer; A J de Boer; S van Tongeren; Gerard Venema; Sierd Bron
Characterization of the replication region of the Bacillus subtilis plasmid pLS20: a novel type of replicon.
Nucleic acids research 1995;23(16):3214-23.
1995: W J Meijer; A de Jong; G Bea; A Wisman; Harold Tjalsma; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
The endogenous Bacillus subtilis (natto) plasmids pTA1015 and pTA1040 contain signal peptidase-encoding genes: identification of a new structural module on cryptic plasmids.
Molecular microbiology 1995;17(4):621-31.
1995: K Venema; Jan Kok; J D Marugg; M Y Toonen; A M Ledeboer; Gerard Venema; Michael Chikindas
Functional analysis of the pediocin operon of Pediococcus acidilactici PAC1.0: PedB is the immunity protein and PedD is the precursor processing enzyme.
Molecular microbiology 1995;17(3):515-22.
1995: K Venema; Gerard Venema; Jan Kok
Lactococcal bacteriocins: mode of action and immunity.
Trends in microbiology 1995;3(8):299-304.
1995: Vincent G H Eijsink; OR Veltman; W Aukema; Gert Vriend; Gerard Venema
Structural determinants of the stability of thermolysin-like proteinases.
Nature structural biology 1995;2(5):374-9.
1995: Girbe Buist; Jan Kok; Kees Leenhouts; M Dabrowska; Gerard Venema; A J Haandrikman
Molecular cloning and nucleotide sequence of the gene encoding the major peptidoglycan hydrolase of Lactococcus lactis, a muramidase needed for cell separation.
Journal of bacteriology 1995;177(6):1554-63.
1995: W J Meijer; D van der Lelie; Gerard Venema; Sierd Bron
Effects of the generation of single-stranded DNA on the maintenance of plasmid pMV158 and derivatives in Lactococcus lactis.
Plasmid 1995;33(2):91-9.
1995: W J Meijer; D van der Lelie; Gerard Venema; Sierd Bron
Effects of the generation of single-stranded DNA on the maintenance of plasmid pMV158 and derivatives in different Bacillus subtilis strains.
Plasmid 1995;33(2):79-89.
1995: W J Meijer; Gerard Venema; Sierd Bron
Characterization of single strand origins of cryptic rolling-circle plasmids from Bacillus subtilis.
Nucleic acids research 1995;23(4):612-9.
1995: Jan Maarten van Dijl; A de Jong; Gerard Venema; Sierd Bron
Identification of the potential active site of the signal peptidase SipS of Bacillus subtilis. Structural and functional similarities with LexA-like proteases.
The Journal of biological chemistry 1995;270(8):3611-8.
1995: Douwe van Sinderen; A Luttinger; L Kong; David Dubnau; Gerard Venema; Leendert W Hamoen
comK encodes the competence transcription factor, the key regulatory protein for competence development in Bacillus subtilis.
Molecular microbiology 1995;15(3):455-62.
1995: K Leszczyńska; Albert Bolhuis; Kees Leenhouts; Gerard Venema; P Cegłowski
Cloning and molecular analysis of the dihydrofolate reductase gene from Lactococcus lactis.
Applied and environmental microbiology 1995;61(2):561-6.
1995: Jan Kok; K Venema; Gerard Venema
Analysis of lactococcin secretion and immunity in Lactococcus lactis.
Developments in biological standardization 1995;85():653-9.
1995: Igor Mierau; A J Haandrikman; Kees Leenhouts; P S Tan; Wil N Konings; Gerard Venema; Jan Kok
Genetics of peptide degradation in Lactococcus: gene cloning, construction and analysis of peptidase negative mutants.
Developments in biological standardization 1995;85():503-7.
1995: Gerard Venema; A J Haandrikman; Jan Kok
Genetic modification and the proteolytic system of lactococci.
Developments in biological standardization 1995;85():495-502.
1995: Jos Seegers; C M Franke; R Kiewiet; Gerard Venema; Sierd Bron
Use of continuous culture for the selection of plasmids with improved segregational stability.
Plasmid 1995;33(1):71-7.
1995: Leendert W Hamoen; H Eshuis; J Jongbloed; Gerard Venema; Douwe van Sinderen
A small gene, designated comS, located within the coding region of the fourth amino acid-activation domain of srfA, is required for competence development in Bacillus subtilis.
Molecular microbiology 1995;15(1):55-63.
1995: Douwe van Sinderen; R Kiewiet; Gerard Venema
Differential expression of two closely related deoxyribonuclease genes, nucA and nucB, in Bacillus subtilis.
Molecular microbiology 1995;15(2):213-23.
1995: B J Haijema; Leendert W Hamoen; J Kooistra; Gerard Venema; Douwe van Sinderen
Expression of the ATP-dependent deoxyribonuclease of Bacillus subtilis is under competence-mediated control.
Molecular microbiology 1995;15(2):203-11.
1994: K Venema; R E Haverkort; T Abee; A J Haandrikman; Kees Leenhouts; L de Leij; Gerard Venema; Jan Kok
Mode of action of LciA, the lactococcin A immunity protein.
Molecular microbiology 1994;14(3):521-32.
1994: Douwe van Sinderen; Gerard Venema
comK acts as an autoregulatory control switch in the signal transduction route to competence in Bacillus subtilis.
Journal of bacteriology 1994;176(18):5762-70.
1994: Jos Seegers; Sierd Bron; C M Franke; Gerard Venema; R Kiewiet
The majority of lactococcal plasmids carry a highly related replicon.
Microbiology (Reading, England) 1994;140 ( Pt 6)():1291-300.
1994: Igor Mierau; A J Haandrikman; O Velterop; P S Tan; K L Leenhouts; Wil N Konings; Gerard Venema; Jan Kok
Tripeptidase gene (pepT) of Lactococcus lactis: molecular cloning and nucleotide sequencing of pepT and construction of a chromosomal deletion mutant.
Journal of bacteriology 1994;176(10):2854-61.
1994: Bertus van den Burg; B W Dijkstra; Gert Vriend; B Van der Vinne; Gerard Venema; Vincent G H Eijsink
Protein stabilization by hydrophobic interactions at the surface.
European journal of biochemistry / FEBS 1994;220(3):981-5.
1994: F Hardy; Gert Vriend; B van der Vinne; F Frigerio; G Grandi; Gerard Venema; Vincent G H Eijsink
The effect of engineering surface loops on the thermal stability of Bacillus subtilis neutral protease.
Protein engineering 1994;7(3):425-30.
1994: Douwe van Sinderen; A ten Berge; B J Hayema; Leendert W Hamoen; Gerard Venema
Molecular cloning and sequence of comK, a gene required for genetic competence in Bacillus subtilis.
Molecular microbiology 1994;11(4):695-703.
1994: Jan A K W Kiel; J M Boels; G Beldman; Gerard Venema
Glycogen in Bacillus subtilis: molecular characterization of an operon encoding enzymes involved in glycogen biosynthesis and degradation.
Molecular microbiology 1994;11(1):203-18.
1993: J Vehmaanperä; A Görner; Gerard Venema; Sierd Bron; Jan Maarten van Dijl
In vitro assay for the Bacillus subtilis signal peptidase SipS: systems for efficient in vitro transcription-translation and processing of precursors of secreted proteins.
FEMS microbiology letters 1993;114(2):207-14.
1993: S Tynkkynen; Girbe Buist; ER Kunji; Jan Kok; Bert Poolman; Gerard Venema; A Haandrikman
Genetic and biochemical characterization of the oligopeptide transport system of Lactococcus lactis.
Journal of bacteriology 1993;175(23):7523-32.
1993: Michael Chikindas; M J García-Garcerá; A J Driessen; A M Ledeboer; J Nissen-Meyer; Ingolf F Nes; T Abee; Wil N Konings; Gerard Venema
Pediocin PA-1, a bacteriocin from Pediococcus acidilactici PAC1.0, forms hydrophilic pores in the cytoplasmic membrane of target cells.
Applied and environmental microbiology 1993;59(11):3577-84.
1993: R Kiewiet; Sierd Bron; K de Jonge; Gerard Venema; Jos Seegers
Theta replication of the lactococcal plasmid pWVO2.
Molecular microbiology 1993;10(2):319-27.
1993: B Mayo; Jan Kok; W Bockelmann; A Haandrikman; Kees Leenhouts; Gerard Venema
Effect of X-Prolyl Dipeptidyl Aminopeptidase Deficiency on Lactococcus lactis.
Applied and environmental microbiology 1993;59(7):2049-55.
1993: Bertus van den Burg; B W Dijkstra; B van der Vinne; B K Stulp; Vincent G H Eijsink; Gerard Venema
Introduction of disulfide bonds into Bacillus subtilis neutral protease.
Protein engineering 1993;6(5):521-7.
1993: Douwe van Sinderen; G Galli; P Cosmina; F de Ferra; Sebo Withoff; Gerard Venema; G Grandi
Characterization of the srfA locus of Bacillus subtilis: only the valine-activating domain of srfA is involved in the establishment of genetic competence.
Molecular microbiology 1993;8(5):833-41.
1993: P Cosmina; F Rodriguez; F de Ferra; G Grandi; M Perego; Gerard Venema; Douwe van Sinderen
Sequence and analysis of the genetic locus responsible for surfactin synthesis in Bacillus subtilis.
Molecular microbiology 1993;8(5):821-31.
1993: K Venema; Tjakko Abee; A J Haandrikman; Kees Leenhouts; Jan Kok; Wil N Konings; Gerard Venema
Mode of Action of Lactococcin B, a Thiol-Activated Bacteriocin from Lactococcus lactis.
Applied and environmental microbiology 1993;59(4):1041-8.
1993: Igor Mierau; P S Tan; A J Haandrikman; B Mayo; Jan Kok; Kees Leenhouts; Wil N Konings; Gerard Venema
Cloning and sequencing of the gene for a lactococcal endopeptidase, an enzyme with sequence similarity to mammalian enkephalinase.
Journal of bacteriology 1993;175(7):2087-96.
1993: J Kooistra; B J Haijema; Gerard Venema
The Bacillus subtilis addAB genes are fully functional in Escherichia coli.
Molecular microbiology 1993;7(6):915-23.
1993: F Hardy; Gert Vriend; OR Veltman; B van der Vinne; Gerard Venema; Vincent G H Eijsink
Stabilization of Bacillus stearothermophilus neutral protease by introduction of prolines.
FEBS letters 1993;317(1-2):89-92.
1993: R Kiewiet; Jan Kok; J F Seegers; Gerard Venema; Sierd Bron
The Mode of Replication Is a Major Factor in Segregational Plasmid Instability in Lactococcus lactis.
Applied and environmental microbiology 1993;59(2):358-64.
1993: Jan A K W Kiel; J M Boels; A M Ten Berge; Gerard Venema
Two putative insertion sequences flank a truncated glycogen branching enzyme gene in the thermophile Bacillus stearothermophilus CU21.
DNA sequence : the journal of DNA sequencing and mapping 1993;4(1):1-9.
1992: Vincent G H Eijsink; Gert Vriend; B van der Vinne; B Hazes; Bertus van den Burg; Gerard Venema
Effects of changing the interaction between subdomains on the thermostability of Bacillus neutral proteases.
Proteins 1992;14(2):224-36.
1992: J M van der Vossen; J Kodde; A J Haandrikman; Gerard Venema; Jan Kok
Characterization of transcription initiation and termination signals of the proteinase genes of Lactococcus lactis Wg2 and enhancement of proteolysis in L. lactis.
Applied and environmental microbiology 1992;58(9):3142-9.
1992: G Perez-Martinez; Jan Kok; Gerard Venema; Jan Maarten van Dijl; H Smith; Sierd Bron
Protein export elements from Lactococcus lactis.
Molecular & general genetics : MGG 1992;234(3):401-11.
1992: Jan Maarten van Dijl; A de Jong; J Vehmaanperä; Gerard Venema; Sierd Bron
Signal peptidase I of Bacillus subtilis: patterns of conserved amino acids in prokaryotic and eukaryotic type I signal peptidases.
The EMBO journal 1992;11(8):2819-28.
1992: Vincent G H Eijsink; Gert Vriend; J R Van der Zee; Bertus van den Burg; Gerard Venema
Increasing the thermostability of the neutral proteinase of Bacillus stearothermophilus by improvement of internal hydrogen-bonding.
The Biochemical journal 1992;285 ( Pt 2)():625-8.
1992: L Oskam; Gerard Venema; Sierd Bron
Plasmid pTB913 derivatives are segregationally stable in Bacillus subtilis at elevated temperatures.
Plasmid 1992;28(1):70-9.
1992: Vincent G H Eijsink; B W Dijkstra; Gert Vriend; J R van der Zee; OR Veltman; B van der Vinne; Bertus van den Burg; S Kempe; Gerard Venema
The effect of cavity-filling mutations on the thermostability of Bacillus stearothermophilus neutral protease.
Protein engineering 1992;5(5):421-6.
1992: L Oskam; Gerard Venema; Sierd Bron
Plasmid maintenance in Bacillus stearothermophilus is strain-dependent.
FEMS microbiology letters 1992;72(3):203-8.
1992: L Oskam; D J Hillenga; Gerard Venema; Sierd Bron
The integrated state of the rolling-circle plasmid pTB913 in the composite Bacillus plasmid pTB19.
Molecular & general genetics : MGG 1992;233(3):462-8.
1992: M van de Guchte; F J van der Wal; Jan Kok; Gerard Venema
Lysozyme expression in Lactococcus lactis.
Applied microbiology and biotechnology 1992;37(2):216-24.
1992: Vincent G H Eijsink; Gert Vriend; Bertus van den Burg; J R van der Zee; Gerard Venema
Increasing the thermostability of a neutral protease by replacing positively charged amino acids in the N-terminal turn of alpha-helices.
Protein engineering 1992;5(2):165-70.
1992: Vincent G H Eijsink; Gert Vriend; Bertus van den Burg; J R van der Zee; OR Veltman; B K Stulp; Gerard Venema
Introduction of a stabilizing 10 residue beta-hairpin in Bacillus subtilis neutral protease.
Protein engineering 1992;5(2):157-63.
1992: H Laan; Jan Kok; A J Haandrikman; Gerard Venema; Wil N Konings
Localization and accessibility of antigenic sites of the extracellular serine proteinase of Lactococcus lactis.
European journal of biochemistry / FEBS 1992;204(2):815-20.
1992: M J van Belkum; Jan Kok; Gerard Venema
Cloning, sequencing, and expression in Escherichia coli of lcnB, a third bacteriocin determinant from the lactococcal bacteriocin plasmid p9B4-6.
Applied and environmental microbiology 1992;58(2):572-7.
1992: M van de Guchte; Jan Kok; Gerard Venema
Gene expression in Lactococcus lactis.
FEMS microbiology reviews 1992;8(2):73-92.
1992: Jan A K W Kiel; A M Ten Berge; Gerard Venema
Nucleotide sequence of the Synechococcus sp. PCC7942 hemE gene encoding the homologue of mammalian uroporphyrinogen decarboxylase.
DNA sequence : the journal of DNA sequencing and mapping 1992;2(6):415-8.
1992: Jan A K W Kiel; J M Boels; G Beldman; Gerard Venema
The glgB gene from the thermophile Bacillus caldolyticus encodes a thermolabile branching enzyme.
DNA sequence : the journal of DNA sequencing and mapping 1992;3(4):221-32.
1991: Gert Vriend; H J Berendsen; J R van der Zee; Bertus van den Burg; Gerard Venema; Vincent G H Eijsink
Stabilization of the neutral protease of Bacillus stearothermophilus by removal of a buried water molecule.
Protein engineering 1991;4(8):941-5.
1991: Vincent G H Eijsink; Bertus van den Burg; Gerard Venema
High performance affinity chromatography of Bacillus neutral proteases.
Biotechnology and applied biochemistry 1991;14(3):275-83.
1991: M J van Belkum; Jan Kok; Gerard Venema; Helge Holo; Ingolf F Nes; Wil N Konings; T Abee
The bacteriocin lactococcin A specifically increases permeability of lactococcal cytoplasmic membranes in a voltage-independent, protein-mediated manner.
Journal of bacteriology 1991;173(24):7934-41.
1991: Jan A K W Kiel; J M Boels; G Beldman; Gerard Venema
Molecular cloning and nucleotide sequence of the glycogen branching enzyme gene (glgB) from Bacillus stearothermophilus and expression in Escherichia coli and Bacillus subtilis.
Molecular & general genetics : MGG 1991;230(1-2):136-44.
1991: Kees Leenhouts; J Gietema; Jan Kok; Gerard Venema
Chromosomal stabilization of the proteinase genes in Lactococcus lactis.
Applied and environmental microbiology 1991;57(9):2568-75.
1991: Kees Leenhouts; Jan Kok; Gerard Venema
Lactococcal plasmid pWV01 as an integration vector for lactococci.
Applied and environmental microbiology 1991;57(9):2562-7.
1991: Jan Maarten van Dijl; A de Jong; H Smith; Sierd Bron; Gerard Venema
Non-functional expression of Escherichia coli signal peptidase I in Bacillus subtilis.
Journal of general microbiology 1991;137(9):2073-83.
1991: Kees Leenhouts; Jan Kok; Gerard Venema
Replacement recombination in Lactococcus lactis.
Journal of bacteriology 1991;173(15):4794-8.
1991: L Oskam; D J Hillenga; Gerard Venema; Sierd Bron
The large Bacillus plasmid pTB19 contains two integrated rolling-circle plasmids carrying mobilization functions.
Plasmid 1991;26(1):30-9.
1991: Jan Maarten van Dijl; A de Jong; H Smith; Sierd Bron; Gerard Venema
Lack of specific hybridization between the lep genes of Salmonella typhimurium and Bacillus licheniformis.
FEMS microbiology letters 1991;65(3):345-51.
1991: A J Haandrikman; R Meesters; H Laan; Wil N Konings; Jan Kok; Gerard Venema
Processing of the lactococcal extracellular serine proteinase.
Applied and environmental microbiology 1991;57(7):1899-904.
1991: A J Haandrikman; Jan Kok; Gerard Venema
Lactococcal proteinase maturation protein PrtM is a lipoprotein.
Journal of bacteriology 1991;173(14):4517-25.
1991: Bertus van den Burg; H G Enequist; M E van der Haar; Vincent G H Eijsink; B K Stulp; Gerard Venema
A highly thermostable neutral protease from Bacillus caldolyticus: cloning and expression of the gene in Bacillus subtilis and characterization of the gene product.
Journal of bacteriology 1991;173(13):4107-15.
1991: Kees Leenhouts; B Tolner; Sierd Bron; Jan Kok; Gerard Venema; Jos Seegers
Nucleotide sequence and characterization of the broad-host-range lactococcal plasmid pWVO1.
Plasmid 1991;26(1):55-66.
1991: M van de Guchte; T van der Lende; Jan Kok; Gerard Venema
A possible contribution of mRNA secondary structure to translation initiation efficiency in Lactococcus lactis.
FEMS microbiology letters 1991;65(2):201-8.
1991: Vincent G H Eijsink; Bertus van den Burg; Gert Vriend; H J Berendsen; Gerard Venema
Thermostability of Bacillus subtilis neutral protease.
Biochemistry international 1991;24(3):517-25.
1991: J Kooistra; Gerard Venema
Cloning, sequencing, and expression of Bacillus subtilis genes involved in ATP-dependent nuclease synthesis.
Journal of bacteriology 1991;173(12):3644-55.
1991: M van de Guchte; Jan Kok; Gerard Venema
Distance-dependent translational coupling and interference in Lactococcus lactis.
Molecular & general genetics : MGG 1991;227(1):65-71.
1991: Jan Maarten van Dijl; A de Jong; H Smith; Sierd Bron; Gerard Venema
Signal peptidase I overproduction results in increased efficiencies of export and maturation of hybrid secretory proteins in Escherichia coli.
Molecular & general genetics : MGG 1991;227(1):40-8.
1991: Vincent G H Eijsink; J R van der Zee; Bertus van den Burg; Gert Vriend; Gerard Venema
Improving the thermostability of the neutral protease of Bacillus stearothermophilus by replacing a buried asparagine by leucine.
FEBS letters 1991;282(1):13-6.
1991: Sierd Bron; Siger Holsappel; Gerard Venema; B P Peeters
Plasmid deletion formation between short direct repeats in Bacillus subtilis is stimulated by single-stranded rolling-circle replication intermediates.
Molecular & general genetics : MGG 1991;226(1-2):88-96.
1991: P Vos; I J Boerrigter; Girbe Buist; A J Haandrikman; Monique Nijhuis; M B de Reuver; Roland Siezen; Gerard Venema; WILLEM DE VOS; Jan Kok
Engineering of the Lactococcus lactis serine proteinase by construction of hybrid enzymes.
Protein engineering 1991;4(4):479-84.
1991: M J van Belkum; B J Hayema; R E Jeeninga; Jan Kok; Gerard Venema
Organization and nucleotide sequences of two lactococcal bacteriocin operons.
Applied and environmental microbiology 1991;57(2):492-8.
1991: B Mayo; Jan Kok; K Venema; W Bockelmann; M Teuber; H Reinke; Gerard Venema
Molecular cloning and sequence analysis of the X-prolyl dipeptidyl aminopeptidase gene from Lactococcus lactis subsp. cremoris.
Applied and environmental microbiology 1991;57(1):38-44.
1990: Douwe van Sinderen; Sebo Withoff; H Boels; Gerard Venema
Isolation and characterization of comL, a transcription unit involved in competence development of Bacillus subtilis.
Molecular & general genetics : MGG 1990;224(3):396-404.
1990: Bertus van den Burg; Vincent G H Eijsink; B K Stulp; Gerard Venema
Identification of autodigestion target sites in Bacillus subtilis neutral proteinase.
The Biochemical journal 1990;272(1):93-7.
1990: Vincent G H Eijsink; Gert Vriend; Bertus van den Burg; Gerard Venema; B K Stulp
Contribution of the C-terminal amino acid to the stability of Bacillus subtilis neutral protease.
Protein engineering 1990;4(1):99-104.
1990: Kees Leenhouts; Jan Kok; Gerard Venema
Stability of Integrated Plasmids in the Chromosome of Lactococcus lactis.
Applied and environmental microbiology 1990;56(9):2726-35.
1990: Jan Maarten van Dijl; R van den Bergh; T Reversma; H Smith; Sierd Bron; Gerard Venema
Molecular cloning of the Salmonella typhimurium lep gene in Escherichia coli.
Molecular & general genetics : MGG 1990;223(2):233-40.
1990: M van de Guchte; J Kodde; J M van der Vossen; Jan Kok; Gerard Venema
Heterologous gene expression in Lactococcus lactis subsp. lactis: synthesis, secretion, and processing of the Bacillus subtilis neutral protease.
Applied and environmental microbiology 1990;56(9):2606-11.
1990: Peter Haima; Sierd Bron; Gerard Venema
Novel plasmid marker rescue transformation system for molecular cloning in Bacillus subtilis enabling direct selection of recombinants.
Molecular & general genetics : MGG 1990;223(2):185-91.
1990: Peter Haima; D van Sinderen; Sierd Bron; Gerard Venema
An improved beta-galactosidase alpha-complementation system for molecular cloning in Bacillus subtilis.
Gene 1990;93(1):41-7.
1990: A J Haandrikman; C van Leeuwen; Jan Kok; P Vos; WILLEM DE VOS; Gerard Venema
Insertion elements on lactococcal proteinase plasmids.
Applied and environmental microbiology 1990;56(6):1890-6.
1990: Jan A K W Kiel; J M Boels; G Beldman; Gerard Venema
Nucleotide sequence of the Synechococcus sp. PCC7942 branching enzyme gene (glgB): expression in Bacillus subtilis.
Gene 1990;89(1):77-84.
1990: Ad Peijnenburg; Gerard Venema; Sierd Bron
Translational coupling in a penP-lacZ gene fusion in Bacillus subtilis and Escherichia coli: use of AUA as a restart codon.
Molecular & general genetics : MGG 1990;221(2):267-72.
1990: Peter Haima; D van Sinderen; H Schotting; Sierd Bron; Gerard Venema
Development of a beta-galactosidase alpha-complementation system for molecular cloning in Bacillus subtilis.
Gene 1990;86(1):63-9.
1990: D van der Lelie; H A Wösten; Sierd Bron; L Oskam; Gerard Venema
Conjugal mobilization of streptococcal plasmid pMV158 between strains of Lactococcus lactis subsp. lactis.
Journal of bacteriology 1990;172(1):47-52.
1989: D van der Lelie; Sierd Bron; Gerard Venema; L Oskam
Similarity of minus origins of replication and flanking open reading frames of plasmids pUB110, pTB913 and pMV158.
Nucleic acids research 1989;17(18):7283-94.
1989: Jan A K W Kiel; H S Elgersma; G Beldman; J P Vossen; Gerard Venema
Cloning and expression of the branching enzyme gene (glgB) from the cyanobacterium Synechococcus sp. PCC7942 in Escherichia coli.
Gene 1989;78(1):9-17.
1989: M J van Belkum; B J Hayema; A Geis; Jan Kok; Gerard Venema
Cloning of two bacteriocin genes from a lactococcal bacteriocin plasmid.
Applied and environmental microbiology 1989;55(5):1187-91.
1989: A J Haandrikman; Jan Kok; H Laan; S Soemitro; A M Ledeboer; Wil N Konings; Gerard Venema
Identification of a gene required for maturation of an extracellular lactococcal serine proteinase.
Journal of bacteriology 1989;171(5):2789-94.
1989: Ad Peijnenburg; P V Breed; Sierd Bron; Gerard Venema
Plasmid deletion formation in recE4 and addB72 mutants of Bacillus subtilis.
Plasmid 1989;21(3):205-15.
1989: Bertus van den Burg; Vincent G H Eijsink; B K Stulp; Gerard Venema
One-step affinity purification of Bacillus neutral proteases using bacitracin-silica.
Journal of biochemical and biophysical methods 1989;18(3):209-19.
1989: Kees Leenhouts; Jan Kok; Gerard Venema
Campbell-like integration of heterologous plasmid DNA into the chromosome of Lactococcus lactis subsp. lactis.
Applied and environmental microbiology 1989;55(2):394-400.
1989: M van de Guchte; J M van der Vossen; Jan Kok; Gerard Venema
Construction of a lactococcal expression vector: expression of hen egg white lysozyme in Lactococcus lactis subsp. lactis.
Applied and environmental microbiology 1989;55(1):224-8.
1988: H Smith; A de Jong; Sierd Bron; Gerard Venema
Characterization of signal-sequence-coding regions selected from the Bacillus subtilis chromosome.
Gene 1988;70(2):351-61.
1988: J Kooistra; B Vosman; Gerard Venema
Cloning and characterization of a Bacillus subtilis transcription unit involved in ATP-dependent DNase synthesis.
Journal of bacteriology 1988;170(10):4791-7.
1988: Jan Maarten van Dijl; H Smith; Sierd Bron; Gerard Venema
Synthesis and processing of Escherichia coli TEM-beta-lactamase and Bacillus licheniformis alpha-amylase in E. coli: the role of signal peptidase I.
Molecular & general genetics : MGG 1988;214(1):55-61.
1988: B Vosman; G Kuiken; J Kooistra; Gerard Venema
Transformation in Bacillus subtilis: involvement of the 17-kilodalton DNA-entry nuclease and the competence-specific 18-kilodalton protein.
Journal of bacteriology 1988;170(8):3703-10.
1988: Ad Peijnenburg; Sierd Bron; Gerard Venema
Plasmid deletion formation in Bacillus subtilis.
Plasmid 1988;20(1):23-32.
1988: B P Peeters; J H de Boer; Sierd Bron; Gerard Venema
Structural plasmid instability in Bacillus subtilis: effect of direct and inverted repeats.
Molecular & general genetics : MGG 1988;212(3):450-8.
1988: D van der Lelie; J M van der Vossen; Gerard Venema
Effect of Plasmid Incompatibility on DNA Transfer to Streptococcus cremoris.
Applied and environmental microbiology 1988;54(4):865-71.
1988: Jan Kok; Gerard Venema
Genetics of proteinases of lactic acid bacteria.
Biochimie 1988;70(4):475-88.
1988: Jan Kok; D Hill; A J Haandrikman; M J de Reuver; H Laan; Gerard Venema
Deletion analysis of the proteinase gene of Streptococcus cremoris Wg2.
Applied and environmental microbiology 1988;54(1):239-44.
1988: Jan Kok; Kees Leenhouts; A J Haandrikman; A M Ledeboer; Gerard Venema
Nucleotide sequence of the cell wall proteinase gene of Streptococcus cremoris Wg2.
Applied and environmental microbiology 1988;54(1):231-8.
1987: D van der Lelie; Gerard Venema
Bacillus subtilis generates a major specific deletion in pAM beta 1.
Applied and environmental microbiology 1987;53(10):2458-63.
1987: J M van der Vossen; D van der Lelie; Gerard Venema
Isolation and characterization of Streptococcus cremoris Wg2-specific promoters.
Applied and environmental microbiology 1987;53(10):2452-7.
1987: Peter Haima; Sierd Bron; Gerard Venema
The effect of restriction on shotgun cloning and plasmid stability in Bacillus subtilis Marburg.
Molecular & general genetics : MGG 1987;209(2):335-42.
1987: B Vosman; J Kooistra; J Olijve; Gerard Venema
Cloning in Escherichia coli of the gene specifying the DNA-entry nuclease of Bacillus subtilis.
Gene 1987;52(2-3):175-83.
1986: B Vosman; J Kooistra; J Olijve; Gerard Venema
Integration of vector-containing Bacillus subtilis chromosomal DNA by a Campbell-like mechanism.
Molecular & general genetics : MGG 1986;204(3):524-31.
1985: J M van der Vossen; Jan Kok; Gerard Venema
Construction of cloning, promoter-screening, and terminator-screening shuttle vectors for Bacillus subtilis and Streptococcus lactis.
Applied and environmental microbiology 1985;50(2):540-2.
1985: Jan Kok; J M van Dijl; J M van der Vossen; Gerard Venema
Cloning and expression of a Streptococcus cremoris proteinase in Bacillus subtilis and Streptococcus lactis.
Applied and environmental microbiology 1985;50(1):94-101.
1984: Jan Kok; J M van der Vossen; Gerard Venema
Construction of plasmid cloning vectors for lactic streptococci which also replicate in Bacillus subtilis and Escherichia coli.
Applied and environmental microbiology 1984;48(4):726-31.