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SS Bowersox

Research Profile

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Publications

TOP 3
Yuntao Song; SS Bowersox; David T Connor; David J Dooley; Susan M Lotarski; TC Malone; GP Miljanich; E Millerman; Michael F Rafferty; D Rock; Bruce D Roth; J Schmidt; SJ Stoehr; BG Szoke; C Taylor; Mark G Vartanian; Y X Wang
(S)-4-Methyl-2-(methylamino)pentanoic acid [4, 4-bis(4-fluorophenyl)butyl]amide hydrochloride, a novel calcium channel antagonist, is efficacious in several animal models of pain.
Lain-Yen Hu; Todd R Ryder; Michael F Rafferty; MR Feng; Susan M Lotarski; DM Rock; M Sinz; SJ Stoehr; Charles P Taylor; Mark L Weber; SS Bowersox; GP Miljanich; E Millerman; Y X Wang; BG Szoke
Synthesis of a series of 4-benzyloxyaniline analogues as neuronal N-type calcium channel blockers with improved anticonvulsant and analgesic properties.
SS Bowersox; Robert R Luther
Pharmacotherapeutic potential of omega-conotoxin MVIIA (SNX-111), an N-type neuronal calcium channel blocker found in the venom of Conus magus.

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All Publications

2000: Yuntao Song; SS Bowersox; David T Connor; David J Dooley; Susan M Lotarski; TC Malone; GP Miljanich; E Millerman; Michael F Rafferty; D Rock; Bruce D Roth; J Schmidt; SJ Stoehr; BG Szoke; C Taylor; Mark G Vartanian; Y X Wang
(S)-4-Methyl-2-(methylamino)pentanoic acid [4, 4-bis(4-fluorophenyl)butyl]amide hydrochloride, a novel calcium channel antagonist, is efficacious in several animal models of pain.
Journal of medicinal chemistry 2000;43(19):3474-7.
1999: Lain-Yen Hu; Todd R Ryder; Michael F Rafferty; MR Feng; Susan M Lotarski; DM Rock; M Sinz; SJ Stoehr; Charles P Taylor; Mark L Weber; SS Bowersox; GP Miljanich; E Millerman; Y X Wang; BG Szoke
Synthesis of a series of 4-benzyloxyaniline analogues as neuronal N-type calcium channel blockers with improved anticonvulsant and analgesic properties.
Journal of medicinal chemistry 1999;42(20):4239-49.
1998: SS Bowersox; Robert R Luther
Pharmacotherapeutic potential of omega-conotoxin MVIIA (SNX-111), an N-type neuronal calcium channel blocker found in the venom of Conus magus.
Toxicon : official journal of the International Society on Toxinology 1998;36(11):1651-8.
1998: Y X Wang; S Bezprozvannaya; SS Bowersox; L Nadasdi; GP Miljanich; G Mezo; D Silva; K Tarczy-Hornoch; Robert R Luther
Peripheral versus central potencies of N-type voltage-sensitive calcium channel blockers.
Naunyn-Schmiedeberg's archives of pharmacology 1998;357(2):159-68.
1997: William G Brose; D P Gutlove; Robert R Luther; SS Bowersox; Dawn McGuire
Use of intrathecal SNX-111, a novel, N-type, voltage-sensitive, calcium channel blocker, in the management of intractable brachial plexus avulsion pain.
The Clinical journal of pain 1997;13(3):256-9.
1997: Dawn McGuire; SS Bowersox; Jere Fellmann; Robert R Luther
Sympatholysis after neuron-specific, N-type, voltage-sensitive calcium channel blockade: first demonstration of N-channel function in humans.
Journal of cardiovascular pharmacology 1997;30(3):400-3.
1997: SS Bowersox; J Mandema; K Tarczy-Hornoch; GP Miljanich; Robert R Luther
Pharmacokinetics of SNX-111, a selective N-type calcium channel blocker, in rats and cynomolgus monkeys.
Drug metabolism and disposition: the biological fate of chemicals 1997;25(3):379-83.
1997: SS Bowersox; T Singh; Robert R Luther
Selective blockade of N-type voltage-sensitive calcium channels protects against brain injury after transient focal cerebral ischemia in rats.
Brain research 1997;747(2):343-7.
1996: SS Bowersox; T Gadbois; T Singh; M Pettus; Y X Wang; Robert R Luther
Selective N-type neuronal voltage-sensitive calcium channel blocker, SNX-111, produces spinal antinociception in rat models of acute, persistent and neuropathic pain.
The Journal of pharmacology and experimental therapeutics 1996;279(3):1243-9.
1995: SS Bowersox; GP Miljanich; Y Sugiura; C Li; L Nadasdi; B B Hoffman; J Ramachandran; Chien-Ping Ko
Differential blockade of voltage-sensitive calcium channels at the mouse neuromuscular junction by novel omega-conopeptides and omega-agatoxin-IVA.
The Journal of pharmacology and experimental therapeutics 1995;273(1):248-56.
1993: K Valentino; R Newcomb; T Gadbois; T Singh; SS Bowersox; S Bitner; A Justice; D Yamashiro; B B Hoffman; R Ciaranello
A selective N-type calcium channel antagonist protects against neuronal loss after global cerebral ischemia.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(16):7894-7.
1992: SS Bowersox; T Singh; L Nadasdi; Z Zukowska-Grojec; K Valentino; B B Hoffman
Cardiovascular effects of omega-conopeptides in conscious rats: mechanisms of action.
Journal of cardiovascular pharmacology 1992;20(5):756-64.
1991: M Hawkins; S O'Connor; Miodrag Radulovacki; SS Bowersox; E Mignot; William C Dement
Radioligand binding to adenosine receptors and adenosine uptake sites in different brain regions of normal and narcoleptic dogs.
Pharmacology, biochemistry, and behavior 1991;38(1):1-6 3.
1989: E Mignot; Christian Guilleminault; SS Bowersox; B Frusthofer; S Nishino; J Maddaluno; R Ciaranello; William C Dement
Central alpha 1 adrenoceptor subtypes in narcolepsy-cataplexy: a disorder of REM sleep.
Brain research 1989;490(1):186-91.
1989: E Mignot; SS Bowersox; J Maddaluno; William C Dement; R Ciaranello
Evidence for multiple [3H]prazosin binding sites in canine brain membranes.
Brain research 1989;486(1):56-66.
1988: E Mignot; Christian Guilleminault; SS Bowersox; A Rappaport; William C Dement
Role of central alpha-1 adrenoceptors in canine narcolepsy.
The Journal of clinical investigation 1988;82(3):885-94.
1988: E Mignot; Christian Guilleminault; SS Bowersox; A Rappaport; William C Dement
Effect of alpha 1-adrenoceptors blockade with prazosin in canine narcolepsy.
Brain research 1988;444(1):184-8.