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Jouko Vepsalainen

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Olga A Smirnova; Vera L Tunitskaya; Jouko Vepsalainen; Tuomo Keinanen; Sergey N Kochetkov; Leena Alhonen; Mervi T Hyvonen; Maria G Isaguliants; Alexander V Ivanov
Chemically induced oxidative stress increases polyamine levels by activating the transcription of ornithine decarboxylase and spermidine/spermine-N1-acetyltransferase in human hepatoma HUH7 cells.
Maxim A Khomutov; Swati Mandal; Janne Weisell; Neiha Saxena; Alina Simonian; Jouko Vepsalainen; Rentala Madhubala; Sergey N Kochetkov
Novel convenient synthesis of biologically active esters of hydroxylamine.
Sushma Singh; Anupam Jhingran; Ankur Sharma; Alina R Simonian; Pasi Soininen; Jouko Vepsalainen; Alex R Khomutov; Madhubala rentala
Novel agmatine analogue, gamma-guanidinooxypropylamine (GAPA) efficiently inhibits proliferation of Leishmania donovani by depletion of intracellular polyamine levels.

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All Publications

2012: Olga A Smirnova; Vera L Tunitskaya; Jouko Vepsalainen; Tuomo Keinanen; Sergey N Kochetkov; Leena Alhonen; Mervi T Hyvonen; Maria G Isaguliants; Alexander V Ivanov
Chemically induced oxidative stress increases polyamine levels by activating the transcription of ornithine decarboxylase and spermidine/spermine-N1-acetyltransferase in human hepatoma HUH7 cells.
Biochimie 2012;94(9):1876-83.
2010: Maxim A Khomutov; Swati Mandal; Janne Weisell; Neiha Saxena; Alina Simonian; Jouko Vepsalainen; Rentala Madhubala; Sergey N Kochetkov
Novel convenient synthesis of biologically active esters of hydroxylamine.
Amino acids 2010;38(2):509-17.
2008: Sushma Singh; Anupam Jhingran; Ankur Sharma; Alina R Simonian; Pasi Soininen; Jouko Vepsalainen; Alex R Khomutov; Madhubala rentala
Novel agmatine analogue, gamma-guanidinooxypropylamine (GAPA) efficiently inhibits proliferation of Leishmania donovani by depletion of intracellular polyamine levels.
Biochemical and biophysical research communications 2008;375(1):168-72.
2007: Alina Simonian; Alex R Khomutov; Tapani Hyvonen; Nikolay Grigorenko; Tuomo Keinanen; Jouko Vepsalainen; Leena Alhonen; Juhani Janne
Novel CoA-polyamine conjugates for effective inhibition of spermine/spermidine-N1-acetyltransferase.
Nucleosides, nucleotides & nucleic acids 2007;26(10-12):1245-8.
2005: Alina Simonian; Nikolay Grigorenko; Jouko Vepsalainen; Alex R Khomutov
[New charge-deficient agmatine analogs].
Bioorganicheskaia khimiia 2005;31(6):645-50.
2005: Alex R Khomutov; Nikolay Grigorenko; Alexander Demin; Jouko Vepsalainen; Robert A Casero; Patrick M Woster
[A charge-deficient analogue of spermine with chelating properties].
Bioorganicheskaia khimiia 2005;31(3):303-11.
2005: Nikolay Grigorenko; Jouko Vepsalainen; A Jarvinen; Tuomo Keinanen; Leena Alhonen; Juhani Janne; Alex R Khomutov
[New syntheses of alpha-methyl- and alpha,alpha'-dimethylspermine].
Bioorganicheskaia khimiia 2005;31(2):200-5.
2004: Nikolay Grigorenko; Jouko Vepsalainen; A Jarvinen; Tuomo Keinanen; Leena Alhonen; Juhani Janne; A M Kritsyn; Alex R Khomutov
[A new synthesis of alpha-methylspermidine].
Bioorganicheskaia khimiia 2004;30(4):441-5.
2004: Halise Inci Gul; Unsal Calis; Jouko Vepsalainen
Synthesis of some mono-Mannich bases and corresponding azine derivatives and evaluation of their anticonvulsant activity.
Arzneimittel-Forschung 2004;54(7):359-64.
2002: Tiina-Liisa Rasanen; Leena Alhonen; Riitta Sinervirta; Tuomo Keinanen; Karl-Heinz Herzig; Suvikki Suppola; Alex R Khomutov; Jouko Vepsalainen; Juhani Janne
A polyamine analogue prevents acute pancreatitis and restores early liver regeneration in transgenic rats with activated polyamine catabolism.
The Journal of biological chemistry 2002;277(42):39867-72.
2002: Halise Inci Gul; Unsal Calis; Jouko Vepsalainen
Synthesis and evaluation of anticonvulsant activities of some bis Mannich bases and corresponding piperidinols.
Arzneimittel-Forschung 2002;52(12):863-9.
2001: Mustafa Gul; Halise Inci Gul; Jouko Vepsalainen; Ercin Erciyas; Osmo Hanninen
Effect of acetophenone derived Mannich bases on cellular glutathione level in Jurkat cells. A possible mechanism of action.
Arzneimittel-Forschung 2001;51(8):679-82.
2001: Halise Inci Gul; T Ojanen; Jouko Vepsalainen; Mustafa Gul; Ercin Erciyas; Osmo Hanninen
Antifungal activity of some mono, bis and quaternary Mannich bases derived from acetophenone.
Arzneimittel-Forschung 2001;51(1):72-5.
2000: Halise Inci Gul; Jouko Vepsalainen; Mustafa Gul; Ercin Erciyas; Osmo Hanninen
Cytotoxic activities of mono and bis Mannich bases derived from acetophenone against Renca and Jurkat cells.
Pharmaceutica acta Helvetiae 2000;74(4):393-8.
1998: Jarkko Rautio; Hannu Taipale; Jukka Gynther; Jouko Vepsalainen; Tapio Nevalainen; Tomi Jarvinen
In vitro evaluation of acyloxyalkyl esters as dermal prodrugs of ketoprofen and naproxen.
Journal of pharmaceutical sciences 1998;87(12):1622-8.