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Alfons Verbruggen

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Kristof Prinsen; Hubert P Vanbilloen; Guy Bormans; Jan Cleynhens; Marlein Miranda Cona; Natalia Dyubankova; Eveline Lescrinier; Junjie Li; Yicheng Ni; Alfons Verbruggen
Synthesis and biological evaluation of (68)Ga labeled bis-DOTA-3,3'-(benzylidene)-bis-(1H-indole-2-carbohydrazide) as a PET tracer for in vivo visualization of necrosis.
Daisy van Veghel; Alfons Verbruggen; Peter M Blumberg; Jan Cleynhens; Ian A Deandrea-Lazarus; Larry V Pearce; Koen Van Laere; Guy Bormans
New transient receptor potential vanilloid subfamily member 1 positron emission tomography radioligands: synthesis, radiolabeling, and preclinical evaluation.
Ingrid Demedts; Ricard Farré; Tatsuhiro Masaoka; Hubert Van Billoen; Pieter Vanden Berghe; Christophe Vanormelingen; Tim Vanuytsel; Kristien Verbeke; Alfons Verbruggen; Jan Tack
Validation of octanoate breath test for measuring gastric emptying in rats.

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All Publications

2013: Kristof Prinsen; Hubert P Vanbilloen; Guy Bormans; Jan Cleynhens; Marlein Miranda Cona; Natalia Dyubankova; Eveline Lescrinier; Junjie Li; Yicheng Ni; Alfons Verbruggen
Synthesis and biological evaluation of (68)Ga labeled bis-DOTA-3,3'-(benzylidene)-bis-(1H-indole-2-carbohydrazide) as a PET tracer for in vivo visualization of necrosis.
Bioorganic & medicinal chemistry letters 2013;23(11):3216-20.
2013: Daisy van Veghel; Alfons Verbruggen; Peter M Blumberg; Jan Cleynhens; Ian A Deandrea-Lazarus; Larry V Pearce; Koen Van Laere; Guy Bormans
New transient receptor potential vanilloid subfamily member 1 positron emission tomography radioligands: synthesis, radiolabeling, and preclinical evaluation.
ACS chemical neuroscience 2013;4(4):624-34.
2013: Ingrid Demedts; Ricard Farré; Tatsuhiro Masaoka; Hubert Van Billoen; Pieter Vanden Berghe; Christophe Vanormelingen; Tim Vanuytsel; Kristien Verbeke; Alfons Verbruggen; Jan Tack
Validation of octanoate breath test for measuring gastric emptying in rats.
Journal of neurogastroenterology and motility 2013;19(2):171-8.
2013: Junjie Li; Feng Chen; Marlein Miranda Cona; Yuanbo Feng; Raymond Oyen; Alfons Verbruggen; Jie Yu; Jian Zhang; Yicheng Ni
Diverse responses to vascular disrupting agent combretastatin a4 phosphate: a comparative study in rats with hepatic and subcutaneous tumor allografts using MRI biomarkers, microangiography, and histopathology.
Translational oncology 2013;6(1):42-50.
2013: Junjie Li; Feng Chen; Marlein Miranda Cona; Peter De Witte; Yuanbo Feng; Johan Nuyts; Raymond Oyen; Alfons Verbruggen; Jie Yu; Guozhi Zhang; Jian Zhang; Lin Zhou; Yicheng Ni
Sequential systemic administrations of combretastatin A4 Phosphate and radioiodinated hypericin exert synergistic targeted theranostic effects with prolonged survival on SCID mice carrying bifocal tumor xenografts.
Theranostics 2013;3(2):127-37.
2013: Junjie Li; Raymond Oyen; Alfons Verbruggen; Yicheng Ni
Small Molecule Sequential Dual-Targeting Theragnostic Strategy (SMSDTTS): from Preclinical Experiments towards Possible Clinical Anticancer Applications.
Journal of Cancer 2013;4(2):133-45.
2013: Daisy van Veghel; Alfons Verbruggen; Peter M Blumberg; Jan Cleynhens; Larry V Pearce; Koen Van Laere; Guy Bormans
Synthesis and biological evaluation of [¹¹C]SB366791: a new PET-radioligand for in vivo imaging of the TRPV1 receptor.
Nuclear medicine and biology 2013;40(1):141-7.
2013: Sofie Van Binnebeek; Eric Van Cutsem; Bert Vanbilloen; Alfons Verbruggen; Chris Verslype; Karin Haustermans; Luc Mortelmans; Felix M Mottaghy; Christelle Terwinghe; Kristof Baete; Ivan Borbath; Christophe M Deroose
Significant impact of transient deterioration of renal function on dosimetry in PRRT.
Annals of nuclear medicine 2013;27(1):74-7.
2012: Jun-jie Li; Raymond Oyen; Alfons Verbruggen; Guo-zhi Zhang; Feng Chen; Marlein Miranda Cona; Yuan-bo Feng; Xue-bin Fu; Uwe Himmelreich; Yi-cheng Ni
A single-dose toxicity study on non-radioactive iodinated hypericin for a targeted anticancer therapy in mice.
Acta pharmacologica Sinica 2012;33(12):1549-56.
2012: Christophe M Deroose; Rik Gijsbers; Abdelilah Ibrahimi; Veerle Baekelandt; Jan Balzarini; Guy Bormans; Satish K Chitneni; zeger debyser; Johan Nuyts; Alfons Verbruggen; Peter Vermaelen; Luc Mortelmans
Preliminary validation of varicella zoster virus thymidine kinase as a novel reporter gene for PET.
Nuclear medicine and biology 2012;39(8):1266-74.
2012: Marlein Miranda Cona; Peter De Witte; Yuanbo Feng; Junjie Li; Alfons Verbruggen; Huaijun Wang; Feng Chen; Yicheng Ni
Continuing pursuit for ideal systemic anticancer radiotherapeutics.
Investigational new drugs 2012;30(5):2050-65.
2012: Marie Van De Putte; Alfons Verbruggen; Guy Bormans; Marlein Miranda Cona; Humphrey Fonge; Junjie Li; Thierry Marysael; Yicheng Ni; Tania Roskams; Peter A M De Witte
Radiolabeled iodohypericin as tumor necrosis avid tracer: diagnostic and therapeutic potential.
International journal of cancer. Journal international du cancer 2012;131(2):E129-37.
2012: Marlein Miranda Cona; Walter Coudyzer; Yuanbo Feng; Junjie Li; Raymond Oyen; Alfons Verbruggen; Huaijun Wang; Yichao Zheng; Matthias Bauwens; Feng Chen; Yicheng Ni
Study on the microbial safety of an infusion set for contrast-enhanced imaging.
Investigative radiology 2012;47(4):247-51.
2012: Junjie Li; Raymond Oyen; Alfons Verbruggen; Feng Chen; Marlein Miranda Cona; Yuanbo Feng; Uwe Himmelreich; Yicheng Ni
A review on various targeted anticancer therapies.
Targeted oncology 2012;7(1):69-85.
2012: Junjie Li; Feng Chen; Marlein Miranda Cona; Peter De Witte; Yuanbo Feng; Uwe Himmelreich; Johan Nuyts; Alfons Verbruggen; Jie Yu; Jian Zhang; Lin Zhou; Yicheng Ni
Exploring theranostic potentials of radioiodinated hypericin in rodent necrosis models.
Theranostics 2012;2(10):1010-9.
2012: Matthias Bauwens; Laura Brams; Jan Cleynhens; Marijke De Saint-Hubert; Ellen Devos; Felix M Mottaghy; Alfons Verbruggen
Radioiodinated phenylalkyl malonic acid derivatives as pH-sensitive SPECT tracers.
PloS one 2012;7(6):e38428.
2011: Marijke De Saint-Hubert; Ellen Devos; Luc Mortelmans; Yicheng Ni; Chris Reutelingsperger; Alfons Verbruggen; Kathleen Vunckx; Huijun Wang; Lin Zhou; Felix M Mottaghy
Preclinical imaging of therapy response using metabolic and apoptosis molecular imaging.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2011;13(5):995-1002.
2011: Junjie Li; Yaming Li; Guy Marchal; Thierry Marysael; Bin Meng; Luc Mortelmans; Guy Bormans; Feng Chen; Peter De Witte; Zhijun Fang; Dejian Huang; Johan Nuyts; Kristof Prinsen; Haibo Shao; Ziping Sun; Alfons Verbruggen; Huaijun Wang; Xiaoning Wang; Ke Xu; Jie Yu; Jian Zhang; Lin Zhou; Marlein Miranda Cona; Yicheng Ni
A dual-targeting anticancer approach: soil and seed principle.
Radiology 2011;260(3):799-807.
2011: Caroline Vandeputte; Alfons Verbruggen; Veerle Baekelandt; Guy Bormans; Barbara Bosier; zeger debyser; Christophe M Deroose; Nele Evens; Rik Gijsbers; Abdelilah Ibrahimi; Peter Janssen; Didier M Lambert; Jaan Toelen; Anke Van der Perren; Koen Van Laere
A PET brain reporter gene system based on type 2 cannabinoid receptors.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011;52(7):1102-9.
2011: Sofie Van Binnebeek; Eric Van Cutsem; Bert Vanbilloen; Alfons Verbruggen; Chris Verslype; Kristof Baete; Christophe M Deroose; Karin Haustermans; Michel Koole; Luc Mortelmans; Christelle Terwinghe; Felix M Mottaghy
Altered biodistribution of somatostatin analogues after first cycle of Peptide receptor radionuclide therapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(19):e579-81.
2011: Matthias Bauwens; Marijke De Saint-Hubert; Ellen Devos; Niko Deckers; Chris P M Reutelingsperger; Luc Mortelmans; Uwe Himmelreich; Felix M Mottaghy; Alfons Verbruggen
Site-specific 68Ga-labeled Annexin A5 as a PET imaging agent for apoptosis.
Nuclear medicine and biology 2011;38(3):381-92.
2011: Kristof Prinsen; Lixin Jin; Kathleen Vunckx; Marijke De Saint-Hubert; Lin Zhou; Jan Cleynhens; Johan Nuyts; Guy Bormans; Yicheng Ni; Alfons Verbruggen
Radiolabeling and preliminary biological evaluation of a (99m)Tc(CO)(3) labeled 3,3'-(benzylidene)-bis-(1H-indole-2-carbohydrazide) derivative as a potential SPECT tracer for in vivo visualization of necrosis.
Bioorganic & medicinal chemistry letters 2011;21(1):502-5.
2010: Sofie Celen; Michel Koole; Meri De Angelis; Ivan Sannen; Satish K Chitneni; Jesus Alcazar; Stefanie Dedeurwaerdere; Dieder Moechars; Mark Schmidt; Alfons Verbruggen; Xavier Langlois; Koen Van Laere; José Ignacio Andrés; Guy Bormans
Preclinical evaluation of 18F-JNJ41510417 as a radioligand for PET imaging of phosphodiesterase-10A in the brain.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(10):1584-91.
2010: Matthias Bauwens; Rufael Chekol; Hubert P Vanbilloen; Guy Bormans; Alfons Verbruggen
Optimal buffer choice of the radiosynthesis of (68)Ga-Dotatoc for clinical application.
Nuclear medicine communications 2010;31(8):753-8.
2010: Kristof Prinsen; Junjie Li; Hubert P Vanbilloen; Peter Vermaelen; Ellen Devos; Luc Mortelmans; Guy Bormans; Yicheng Ni; Alfons Verbruggen
Development and evaluation of a 68Ga labeled pamoic acid derivative for in vivo visualization of necrosis using positron emission tomography.
Bioorganic & medicinal chemistry 2010;18(14):5274-81.
2010: Vamsidhar Akurathi; Ludwig Dubois; Natasja G Lieuwes; Satish K Chitneni; Bernard J Cleynhens; Daniela Vullo; Claudiu T Supuran; Alfons Verbruggen; Philippe Lambin; Guy Bormans
Synthesis and biological evaluation of a 99mTc-labelled sulfonamide conjugate for in vivo visualization of carbonic anhydrase IX expression in tumor hypoxia.
Nuclear medicine and biology 2010;37(5):557-64.
2010: Fabián León-Tamariz; Isabelle Verbaeys; Maurits Van Boven; Marcel De Cuyper; Johan Buyse; Peter De Witte; Alfons Verbruggen; Marnix Cokelaere
Biodistribution and pharmacokinetics of PEG-10kDa-cholecystokinin-10 in rats after different routes of administration.
Current drug delivery 2010;7(2):137-43.
2010: Marijke De Saint-Hubert; Felix M Mottaghy; Kathleen Vunckx; Johan Nuyts; Humphrey Fonge; Kristof Prinsen; Sigrid Stroobants; Luc Mortelmans; Niko Deckers; Leo Hofstra; Chris P M Reutelingsperger; Alfons Verbruggen; Dirk Rattat
Site-specific labeling of 'second generation' annexin V with 99mTc(CO)3 for improved imaging of apoptosis in vivo.
Bioorganic & medicinal chemistry 2010;18(3):1356-63.
2010: Humphrey Fonge; Lixin Jin; Jan Cleynhens; Guy Bormans; Alfons Verbruggen
99mTc-tricarbonyl labeled agents for cell labeling: development, biodistribution in normal mice and preliminary in vitro evaluation.
Bioorganic & medicinal chemistry 2010;18(1):396-402.
2009: Kim Serdons; Koen Van Laere; Peter Janssen; Hank F Kung; Guy Bormans; Alfons Verbruggen
Synthesis and evaluation of three 18F-labeled aminophenylbenzothiazoles as amyloid imaging agents.
Journal of medicinal chemistry 2009;52(22):7090-102.
2009: Silvia Jansen; Maria Andries; Katrien Vekemans; Hubert Vanbilloen; Alfons Verbruggen; Mathieu Bollen
Rapid clearance of the circulating metastatic factor autotaxin by the scavenger receptors of liver sinusoidal endothelial cells.
Cancer letters 2009;284(2):216-21.
2009: Sofie Celen; Jan Cleynhens; Christophe Deroose; Tjibbe de Groot; Abdelilah Ibrahimi; Rik Gijsbers; zeger debyser; Luc Mortelmans; Alfons Verbruggen; Guy Bormans
Synthesis and biological evaluation of (11)C-labeled beta-galactosyl triazoles as potential PET tracers for in vivo LacZ reporter gene imaging.
Bioorganic & medicinal chemistry 2009;17(14):5117-25.
2009: Marijke De Saint-Hubert; Kristof Prinsen; Luc Mortelmans; Alfons Verbruggen; Felix Mottaghy
Molecular imaging of cell death.
Methods (San Diego, Calif.) 2009;48(2):178-87.
2009: K Serdons; T Verduyckt; D Vanderghinste; Peter Borghgraef; J Cleynhens; Fred Van Leuven; H Kung; Guy Bormans; Alfons Verbruggen
11C-labelled PIB analogues as potential tracer agents for in vivo imaging of amyloid beta in Alzheimer's disease.
European journal of medicinal chemistry 2009;44(4):1415-26.
2009: Kim Serdons; Christelle Terwinghe; Peter Vermaelen; Koen Van Laere; Hank Kung; Luc Mortelmans; Guy Bormans; Alfons Verbruggen
Synthesis and evaluation of 18F-labeled 2-phenylbenzothiazoles as positron emission tomography imaging agents for amyloid plaques in Alzheimer's disease.
Journal of medicinal chemistry 2009;52(5):1428-37.
2008: Kim Serdons; Alfons Verbruggen; Guy Bormans
The presence of ethanol in radiopharmaceutical injections.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(12):2071.
2008: Humphrey Fonge; Marijke de Saint Hubert; Kathleen Vunckx; Dirk Rattat; Johan Nuyts; Guy Bormans; Yicheng Ni; Chris Reutelingsperger; Alfons Verbruggen
Preliminary in vivo evaluation of a novel 99mTc-labeled HYNIC-cys-annexin A5 as an apoptosis imaging agent.
Bioorganic & medicinal chemistry letters 2008;18(13):3794-8.
2008: Satish K Chitneni; Kim Serdons; Nele Evens; Humphrey Fonge; Sofie Celen; Christophe M Deroose; zeger debyser; Luc Mortelmans; Alfons Verbruggen; Guy Bormans
Efficient purification and metabolite analysis of radiotracers using high-performance liquid chromatography and on-line solid-phase extraction.
Journal of chromatography. A 2008;1189(1-2):323-31.
2008: Carmen Burtea; Sophie Laurent; Oltea Murariu; Dirk Rattat; Gérard Toubeau; Alfons Verbruggen; David Vansthertem; Luce Vander Elst; Robert N Muller
Molecular imaging of alpha v beta3 integrin expression in atherosclerotic plaques with a mimetic of RGD peptide grafted to Gd-DTPA.
Cardiovascular research 2008;78(1):148-57.
2008: Sofie Celen; Christophe M Deroose; Tjibbe de Groot; Satish K Chitneni; Rik Gijsbers; zeger debyser; Luc Mortelmans; Alfons Verbruggen; Guy Bormans
Synthesis and evaluation of 18F- and 11C-labeled phenyl-galactopyranosides as potential probes for in vivo visualization of LacZ gene expression using positron emission tomography.
Bioconjugate chemistry 2008;19(2):441-9.
2008: Satish K Chitneni; Lucette Garreau; Bernard J Cleynhens; Nele Evens; Marva Bex; Peter Vermaelen; Sylvie Chalon; Roger Busson; Denis Guilloteau; Koen Van Laere; Alfons Verbruggen; Guy Bormans
Improved synthesis and metabolic stability analysis of the dopamine transporter ligand [(18)F]FECT.
Nuclear medicine and biology 2008;35(1):75-82.
2008: Humphrey Fonge; Kathleen Vunckx; Huaijun Wang; Yuanbo Feng; Luc Mortelmans; Johan Nuyts; Guy Bormans; Alfons Verbruggen; Yicheng Ni
Non-invasive detection and quantification of acute myocardial infarction in rabbits using mono-[123I]iodohypericin microSPECT.
European heart journal 2008;29(2):260-9.
2007: Satish K Chitneni; Christophe M Deroose; Jan Balzarini; Rik Gijsbers; Sofie Celen; zeger debyser; Luc Mortelmans; Alfons Verbruggen; Guy Bormans
A p-[18F]fluoroethoxyphenyl bicyclic nucleoside analogue as a potential positron emission tomography imaging agent for varicella-zoster virus thymidine kinase gene expression.
Journal of medicinal chemistry 2007;50(26):6627-37.
2007: K Serdons; T Verduyckt; J Cleynhens; Christelle Terwinghe; Luc Mortelmans; Guy Bormans; Alfons Verbruggen
Synthesis and evaluation of a (99m)Tc-BAT-phenylbenzothiazole conjugate as a potential in vivo tracer for visualization of amyloid beta.
Bioorganic & medicinal chemistry letters 2007;17(22):6086-90.
2007: Humphrey Fonge; Satish K Chitneni; Jin Lixin; Kathleen Vunckx; Kristof Prinsen; Johan Nuyts; Luc Mortelmans; Guy Bormans; Yicheng Ni; Alfons Verbruggen
Necrosis avidity of (99m)Tc(CO)3-labeled pamoic acid derivatives: synthesis and preliminary biological evaluation in animal models of necrosis.
Bioconjugate chemistry 2007;18(6):1924-34.
2007: Natalie Nelissen; Mathieu Vandenbulcke; Katrien Fannes; Alfons Verbruggen; Ronald Peeters; Patrick Dupont; Koen Van Laere; Guy Bormans; Rik Vandenberghe
Abeta amyloid deposition in the language system and how the brain responds.
Brain : a journal of neurology 2007;130(Pt 8):2055-69.
2007: Humphrey Fonge; Lixin Jin; Huaijun Wang; Yicheng Ni; Guy Bormans; Alfons Verbruggen
Synthesis and preliminary evaluation of mono-[123I]iodohypericin monocarboxylic acid as a necrosis avid imaging agent.
Bioorganic & medicinal chemistry letters 2007;17(14):4001-5.
2007: Wouter A P Breeman; Alfons Verbruggen
The 68Ge/ 68Ga generator has high potential, but when can we use 68Ga-labelled tracers in clinical routine?
European journal of nuclear medicine and molecular imaging 2007;34(7):978-81.
2007: Satish K Chitneni; Christophe M Deroose; Humphrey Fonge; Rik Gijsbers; Natalia Dyubankova; Jan Balzarini; zeger debyser; Luc Mortelmans; Alfons Verbruggen; Guy Bormans
Synthesis and biological evaluation of an 123I-labeled bicyclic nucleoside analogue (BCNA) as potential SPECT tracer for VZV-tk reporter gene imaging.
Bioorganic & medicinal chemistry letters 2007;17(12):3458-62.
2007: Humphrey Fonge; Marie Van De Putte; Dieter Huyghe; Guy Bormans; Yicheng Ni; Peter De Witte; Alfons Verbruggen
Evaluation of tumor affinity of mono-[(123)I]iodohypericin and mono-[(123)I]iodoprotohypericin in a mouse model with a RIF-1 tumor.
Contrast media & molecular imaging 2007;2(3):113-9.
2007: Sofie Celen; Tjibbe de Groot; Jan Balzarini; Kathleen Vunckx; Christelle Terwinghe; Peter Vermaelen; Lizette Van Berckelaer; Hubert P Vanbilloen; Johan Nuyts; Luc Mortelmans; Alfons Verbruggen; Guy Bormans
Synthesis and evaluation of a (99m)Tc-MAMA-propyl-thymidine complex as a potential probe for in vivo visualization of tumor cell proliferation with SPECT.
Nuclear medicine and biology 2007;34(3):283-91.
2007: Satish K Chitneni; Christophe M Deroose; Jan Balzarini; Rik Gijsbers; Sofie Celen; Tjibbe de Groot; zeger debyser; Luc Mortelmans; Alfons Verbruggen; Guy Bormans
Synthesis and preliminary evaluation of 18F- or 11C-labeled bicyclic nucleoside analogues as potential probes for imaging varicella-zoster virus thymidine kinase gene expression using positron emission tomography.
Journal of medicinal chemistry 2007;50(5):1041-9.
2006: Yicheng Ni; Dieter Huyghe; Kristin Verbeke; Peter A M De Witte; Johan Nuyts; Luc Mortelmans; Feng Chen; Guy Marchal; Alfons Verbruggen; Guy Bormans
First preclinical evaluation of mono-[123I]iodohypericin as a necrosis-avid tracer agent.
European journal of nuclear medicine and molecular imaging 2006;33(5):595-601.
2006: Yicheng Ni; Feng Chen; Stefaan Mulier; Xihe Sun; Jie Yu; Willy Landuyt; Guy Marchal; Alfons Verbruggen
Magnetic resonance imaging after radiofrequency ablation in a rodent model of liver tumor: tissue characterization using a novel necrosis-avid contrast agent.
European radiology 2006;16(5):1031-40.
2006: Hubert P Vanbilloen; davy Kieffer; Bernard J Cleynhens; Guy Bormans; Luc Mortelmans; Alfons Verbruggen
Evaluation of (99m)Tc-labeled tropanes with alkyl substituents on the 3beta-phenyl ring as potential dopamine transporter tracers.
Nuclear medicine and biology 2006;33(3):413-8.
2006: Koen Van Laere; Cindy Casteels; Liesbet De Ceuninck; Bert Vanbilloen; Alex Maes; Luc Mortelmans; Wim Vandenberghe; Alfons Verbruggen; René Dom
Dual-tracer dopamine transporter and perfusion SPECT in differential diagnosis of parkinsonism using template-based discriminant analysis.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(3):384-92.
2006: Marie Van De Putte; Tania Roskams; Guy Bormans; Alfons Verbruggen; Peter A M De Witte
The impact of aggregation on the biodistribution of hypericin.
International journal of oncology 2006;28(3):655-60.
2006: davy Kieffer; Bernard J Cleynhens; Hubert P Vanbilloen; Dirk Rattat; Christelle Terwinghe; Luc Mortelmans; Guy Bormans; Alfons Verbruggen
Synthesis and biological evaluation of a technetium-99m(I)-tricarbonyl-labelled phenyltropane derivative.
Bioorganic & medicinal chemistry letters 2006;16(2):382-6.
2006: Jan Balzarini; Sofie Celen; Anna Karlsson; Tjibbe de Groot; Alfons Verbruggen; Guy Bormans
The effect of a methyl or 2-fluoroethyl substituent at the N-3 position of thymidine, 3'-fluoro-3'-deoxythymidine and 1-beta-D-arabinosylthymine on their antiviral and cytostatic activity in cell culture.
Antiviral chemistry & chemotherapy 2006;17(1):17-23.
2006: davy Kieffer; Hubert P Vanbilloen; Bernard J Cleynhens; Christelle Terwinghe; Luc Mortelmans; Guy Bormans; Alfons Verbruggen
Biological evaluation of a technetium-99m-labeled integrated tropane-BAT and its piperidine congener as potential dopamine transporter imaging agents.
Nuclear medicine and biology 2006;33(1):125-33.
2005: Dirk Rattat; Bernard J Cleynhens; Guy Bormans; Christelle Terwinghe; Alfons Verbruggen
Characterisation and biodistribution of two neutral 99mTc(CO)3 complexes with a tridentate ligand.
Bioorganic & medicinal chemistry letters 2005;15(19):4192-5.
2005: Hubert P Vanbilloen; davy Kieffer; Bernard J Cleynhens; Guy Bormans; Luc Mortelmans; Alfons Verbruggen
Development and biological evaluation of 99mTc-BAT-tropane esters.
Nuclear medicine and biology 2005;32(6):607-12.
2005: Yicheng Ni; Guy Bormans; Feng Chen; Alfons Verbruggen; Guy Marchal
Necrosis avid contrast agents: functional similarity versus structural diversity.
Investigative radiology 2005;40(8):526-35.
2005: Tatjana N Parac-Vogt; Kristof Kimpe; Sophie Laurent; Luce Vander Elst; Carmen Burtea; Feng Chen; Robert N Muller; Yicheng Ni; Alfons Verbruggen; Koen Binnemans
Synthesis, characterization, and pharmacokinetic evaluation of a potential MRI contrast agent containing two paramagnetic centers with albumin binding affinity.
Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(10):3077-86.
2005: Bernard J Cleynhens; Tjibbe de Groot; Hubert P Vanbilloen; davy Kieffer; Luc Mortelmans; Guy Bormans; Alfons Verbruggen
Technetium-99m labelled integrated tropane-BAT as a potential dopamine transporter tracer.
Bioorganic & medicinal chemistry 2005;13(4):1053-8.
2004: Koen Van Laere; Liesbet De Ceuninck; René Dom; J Van den Eynden; Hubert P Vanbilloen; J Cleynhens; Patrick Dupont; Guy Bormans; Alfons Verbruggen; Luc Mortelmans
Dopamine transporter SPECT using fast kinetic ligands: 123I-FP-beta-CIT versus 99mTc-TRODAT-1.
European journal of nuclear medicine and molecular imaging 2004;31(8):1119-27.
2004: gerard PERRET; Anna Starzec; Nathalie Hauet; Jackie Vergote; Marie Le Pecheur; Roger Vassy; Gérard Léger; Kristin Verbeke; Guy Bormans; Patrick Nicolas; Alfons Verbruggen; Jean-Luc Moretti
In vitro evaluation and biodistribution of a 99mTc-labeled anti-VEGF peptide targeting neuropilin-1.
Nuclear medicine and biology 2004;31(5):575-81.
2003: Ann Huygens; Dieter Huyghe; Guy Bormans; Alfons Verbruggen; Appolinary R Kamuhabwa; Tania Roskams; Peter A M De Witte
Accumulation and photocytotoxicity of hypericin and analogs in two- and three-dimensional cultures of transitional cell carcinoma cells.
Photochemistry and photobiology 2003;78(6):607-14.
2003: Tjibbe de Groot; Maike Veyhl; Christelle Terwinghe; Véronique Vanden Bempt; Patrick Dupont; Luc Mortelmans; Alfons Verbruggen; Guy Bormans; Hermann Koepsell
Synthesis of 18F-fluoroalkyl-beta-D-glucosides and their evaluation as tracers for sodium-dependent glucose transporters.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2003;44(12):1973-81.
2003: Kristin Verbeke; davy Kieffer; Jean-Luc Vanderheyden; Chris P M Reutelingsperger; Neil Steinmetz; Allan Green; Alfons Verbruggen
Optimization of the preparation of 99mTc-labeled Hynic-derivatized Annexin V for human use.
Nuclear medicine and biology 2003;30(7):771-8.
2003: D Vanderghinste; M Van Eeckhoudt; Christelle Terwinghe; Luc Mortelmans; Guy Bormans; Alfons Verbruggen; Hubert P Vanbilloen
An efficient HPLC method for the analysis of isomeric purity of technetium-99m-exametazime and identity confirmation using LC-MS.
Journal of pharmaceutical and biomedical analysis 2003;32(4-5):679-85.
2003: Tom Verduyckt; davy Kieffer; Dieter Huyghe; Bernard J Cleynhens; Kristin Verbeke; Alfons Verbruggen; Guy Bormans
Identity confirmation of 99mTc-MAG3, 99mTc-sestamibi and 99mTc-ECD using radio-LC-MS.
Journal of pharmaceutical and biomedical analysis 2003;32(4-5):669-78.
2003: Hubert P Vanbilloen; Bernard J Cleynhens; Tjibbe de Groot; Alex Maes; Guy Bormans; Alfons Verbruggen
RP-HPLC separation of the diastereomers of technetium-99m labelled tropanes and identity confirmation using radio-LC-MS.
Journal of pharmaceutical and biomedical analysis 2003;32(4-5):663-8.
2003: Guy Bormans; Griet Van Oosterwyck; Tjibbe de Groot; Maike Veyhl; Luc Mortelmans; Alfons Verbruggen; Hermann Koepsell
Synthesis and biologic evaluation of (11)c-methyl-d-glucoside, a tracer of the sodium-dependent glucose transporters.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2003;44(7):1075-81.
2003: Gerrit J Kemerink; Xuan Liu; davy Kieffer; Sarah Ceyssens; Luc Mortelmans; Alfons Verbruggen; Neil Steinmetz; Jean-Luc Vanderheyden; Allan M Green; Kristin Verbeke
Safety, biodistribution, and dosimetry of 99mTc-HYNIC-annexin V, a novel human recombinant annexin V for human application.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2003;44(6):947-52.
2003: Alex Maes; Hubert P Vanbilloen; Bernard J Cleynhens; Luc Mortelmans; Guy Bormans; Alfons Verbruggen
99mTc-M-TRODAT is not superior to (99m)Tc-TRODAT-1 for the diagnosis of Parkinson's disease.
European journal of nuclear medicine and molecular imaging 2003;30(5):796-7.
2003: Benedicte Vanquickenborne; Alex Maes; Johan Nuyts; Frank Van Acker; Jos Stuyck; Michiel Mulier; Alfons Verbruggen; Luc Mortelmans
The value of (18)FDG-PET for the detection of infected hip prosthesis.
European journal of nuclear medicine and molecular imaging 2003;30(5):705-15.
2003: Christa Gilissen; Tjibbe de Groot; Francesca Bronfman; Fred Van Leuven; Alfons Verbruggen; Guy Bormans
Evaluation of 18F-FA-4 and 11C-pipzA-4 as radioligands for the in vivo evaluation of the high-affinity choline uptake system.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2003;44(2):269-75.
2002: Yicheng Ni; Erwin Cresens; Paul Adriaens; Steven Dymarkowski; Jan Bogaert; Hao Zhang; Hilde Bosmans; Alfons Verbruggen; Guy Marchal
Exploring multifunctional features of necrosis avid contrast agents.
Academic radiology 2002;9 Suppl 2():S488-90.
2002: Kristin Verbeke; A Verbeke; Hubert P Vanbilloen; Alfons Verbruggen
Preparation and preliminary evaluation of 99mTc-EC-For-MLFK.
Nuclear medicine and biology 2002;29(5):585-92.
2002: Yicheng Ni; Erwin Cresens; Paul Adriaens; Yi Miao; Kristin Verbeke; Steven Dymarkowski; Alfons Verbruggen; Guy Marchall
Necrosis-avid contrast agents: introducing nonporphyrin species.
Academic radiology 2002;9 Suppl 1():S98-101.
2002: Patrick K Coussement; Pieter R Stella; Hubert P Vanbilloen; Alfons Verbruggen; Peter P van Rijk; A Hoekstra; Erik Van Limbergen; Peter P T de Jaegere; Ivan De Scheerder
Intracoronary beta-radiation of de novo coronary lesions using a (186)Re liquid-filled balloon system: six-month results from a clinical feasibility study.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2002;55(1):28-36.
2002: Kristin Verbeke; Jef Rozenski; Bernard J Cleynhens; Hubert P Vanbilloen; Tjibbe de Groot; Nancy Weyns; Guy Bormans; Alfons Verbruggen
Development of a conjugate of (99m)Tc-EC with aminomethylenediphosphonate in the search for a bone tracer with fast clearance from soft tissue.
Bioconjugate chemistry 2002;13(1):16-22.
2001: Abderrahim Nemmar; Hubert P Vanbilloen; M F Hoylaerts; Peter H M Hoet; Alfons Verbruggen; B Nemery
Passage of intratracheally instilled ultrafine particles from the lung into the systemic circulation in hamster.
American journal of respiratory and critical care medicine 2001;164(9):1665-8.
2001: NA Dezutter; Wil Landman; P L Jager; Tjibbe de Groot; Patrick Dupont; Peter C J Tooten; Bereket Zekarias; Erik Gruys; Alfons Verbruggen
Evaluation of 99mTc-MAMA-chrysamine G as an in vivo probe for amyloidosis.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2001;8(3):202-14.
2001: NA Dezutter; Raf Sciot; Tjibbe de Groot; Guy Bormans; Alfons Verbruggen
In vitro affinity of 99Tcm-labelled N2S2 conjugates of chrysamine G for amyloid deposits of systemic amyloidosis.
Nuclear medicine communications 2001;22(5):553-8.
2001: Christiaan Schiepers; Liesbet Mesotten; W Proesmans; Raoul Vereecken; Alfons Verbruggen; MJ de Roo
Surgical correction of vesicoureteral reflux: 5-year follow-up with 99Tcm-DMSA scintigraphy.
Nuclear medicine communications 2001;22(2):217-24.
2000: K Mang'era; Hubert P Vanbilloen; Bernard J Cleynhens; Guy Bormans; Alfons Verbruggen; Kristin Verbeke
Synthesis and evaluation of the (99m)tc-complexes of L-cysteine acetyldiglycine (a hybrid of MAG3 and L,L-EC) and of L-beta-homocysteine acetyldiglycine.
Nuclear medicine and biology 2000;27(8):781-9.
2000: Kristin Verbeke; K Snauwaert; Bernard J Cleynhens; W Scheers; Alfons Verbruggen
Influence of the bifunctional chelate on the biological behavior of (99m)Tc-labeled chemotactic peptide conjugates.
Nuclear medicine and biology 2000;27(8):769-79.
2000: Michael I Ugwoke; Remigius U Agu; Hubert P Vanbilloen; J Baetens; Patrick Augustijns; Norbert Verbeke; Luc Mortelmans; Alfons Verbruggen; Renaat Kinget; Guy Bormans
Scintigraphic evaluation in rabbits of nasal drug delivery systems based on carbopol 971p((R)) and carboxymethylcellulose.
Journal of controlled release : official journal of the Controlled Release Society 2000;68(2):207-14.
2000: Patrick K Coussement; Pieter R Stella; Hubert P Vanbilloen; Alfons Verbruggen; Peter P van Rijk; Erik Van Limbergen; Peter P T de Jaegere; Ivan De Scheerder
Coronary radiation therapy with liquid rhenium-186: a first clinical experience.
The Journal of invasive cardiology 2000;12(4):206-10.
2000: Hubert P Vanbilloen; Bernard J Cleynhens; Alfons Verbruggen
Synthesis and biological evaluation of the four isomers of technetium-99m labeled ethylenecysteamine cysteine ((99m)Tc-ECC), the mono-acid derivative of (99m)tc-L,L-ethylenedicysteine.
Nuclear medicine and biology 2000;27(2):207-14.
1999: K O Mang'era; Alfons Verbruggen
HPLC separation of 99mTc-L-cysteine acetyldiglycine diethylester and its monoester-monoacid and diacid derivatives.
Journal of pharmaceutical and biomedical analysis 1999;21(3):679-83.
1999: NA Dezutter; René Dom; Tjibbe de Groot; Guy Bormans; Alfons Verbruggen
99mTc-MAMA-chrysamine G, a probe for beta-amyloid protein of Alzheimer's disease.
European journal of nuclear medicine 1999;26(11):1392-9.
1999: Hubert P Vanbilloen; Patrick Dupont; Liesbet Mesotten; Luc Mortelmans; Kristin Verbeke; Alfons Verbruggen; Wim Van Paesschen; Guido Van Driel
Simple design for rapid self-injection ictal SPET during aura.
European journal of nuclear medicine 1999;26(10):1380-1.
1999: Hubert P Vanbilloen; J Bauwens; L Mortelmans; Alfons Verbruggen
Reduction of contamination risks during clinical studies with technegas.
European journal of nuclear medicine 1999;26(10):1349-52.
1998: Hubert P Vanbilloen; Bernard J Cleynhens; Alfons Verbruggen
Importance of the two ester functions for the brain retention of 99mTc-labelled ethylene dicysteine diethyl ester (99mTc-ECD).
Nuclear medicine and biology 1998;25(6):569-75.
1998: Anne Van Hecken; M Depré; K Wynants; Hubert P Vanbilloen; Alfons Verbruggen; Jef Arnout; P Vanhove; R Cariou; Paul De Schepper
Effect of clopidogrel on naproxen-induced gastrointestinal blood loss in healthy volunteers.
Drug metabolism and drug interactions 1998;14(3):193-205.
1997: Christiaan Schiepers; Johan Nuyts; Guy Bormans; J Dequeker; Roger Bouillon; Luc Mortelmans; Alfons Verbruggen; MJ de Roo
Fluoride kinetics of the axial skeleton measured in vivo with fluorine-18-fluoride PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997;38(12):1970-6.
1997: Hubert P Vanbilloen; NA Dezutter; Bernard J Cleynhens; Alfons Verbruggen
Characteristics and biological behaviour of 99mTc-labelled hydroxyacetyltriglycine, a potential alternative to 99mTc-MAG3.
European journal of nuclear medicine 1997;24(11):1374-9.
1997: A S Hambÿe; Kristin Verbeke; R P Vandermeiren; E J Joosens; Alfons Verbruggen; MJ de Roo
Comparison of modified technetium-99m albumin and technetium-99m red blood cells for equilibrium ventriculography.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997;38(10):1521-8.
1997: A Van Schepdael; Kristin Verbeke; C Van Nerom; Jos Hoogmartens; Alfons Verbruggen
Capillary electrophoretic analysis of ethylene dicysteine, a precursor of the radiopharmaceutical 99mTc ethylene dicysteine.
Journal of chromatography. B, Biomedical sciences and applications 1997;697(1-2):251-4.
1997: Kristin Verbeke; C W Schiepers; D N Wyndaele; J A Baetens; Geert Verbeke; MJ de Roo; Alfons Verbruggen
Development and evaluation of a kit formulation for the preparation of 99mTc-DMP-HSA, a new tracer agent for radionuclide ventriculography.
Nuclear medicine and biology 1997;24(6):571-8.
1997: Tjibbe de Groot; B Maris; C Boonen; Guy Bormans; Luc Mortelmans; M Eisenhut; Alfons Verbruggen
Evaluation of carbon-11-labelled phenoxy bridged fatty acids for studying myocardial fatty acid metabolism with PET.
Nuclear medicine and biology 1997;24(5):461-4.
1997: Christiaan Schiepers; Alfons Verbruggen; P Casaer; MJ de Roo
Normal brain perfusion pattern of technetium-99m-ethylcysteinate dimer in children.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997;38(7):1115-20.
1997: Kristin Verbeke; C Boonen; Alfons Verbruggen
Usefulness of residual fractions of L,L-ethylcysteinate dimer (Neurolite) for the preparation of 99Tc(m)-L,L-ethylcysteinate dimer.
Nuclear medicine communications 1997;18(6):535-9.
1997: J P Cambier; Kristin Verbeke; Hubert P Vanbilloen; Guy Bormans; MJ de Roo; Alfons Verbruggen
99Tcm-dimercaptopropionyl-HSA prepared from a labelling kit: preliminary investigations as a blood pool agent.
Nuclear medicine communications 1997;18(1):31-7.
1996: AM Rosier; Patrick Dupont; Joseph Peuskens; Guy Bormans; Rik Vandenberghe; M Maes; T de Groot; Christiaan Schiepers; Alfons Verbruggen; Luc Mortelmans
Visualisation of loss of 5-HT2A receptors with age in healthy volunteers using [18F]altanserin and positron emission tomographic imaging.
Psychiatry research 1996;68(1):11-22.
1996: K O Mang'era; Hubert P Vanbilloen; E Bellande; R Pasqualini; Alfons Verbruggen
Influence of a 99mTcN core on the biological and physicochemical behavior of 99mTc complexes of L,L-EC and L,L-ECD.
Nuclear medicine and biology 1996;23(8):987-93.
1996: E Krznaric; M D Roo; Alfons Verbruggen; Jos Stuyck; Luc Mortelmans
Chronic osteomyelitis: diagnosis with technetium-99m-d, l-hexamethylpropylene amine oxime labelled leucocytes.
European journal of nuclear medicine 1996;23(7):792-7.
1996: K O Mang'era; E Bellande; R Pasqualini; Alfons Verbruggen
Comparison of reversed phase and reversed phase ion pair high performance liquid chromatography for analysis of TcO and TcN complexes of L,L-ethylene dicysteine di-ethylester and its acid analogues.
Journal of pharmaceutical and biomedical analysis 1996;14(8-10):1241-4.
1996: Kristin Verbeke; Alfons Verbruggen
Usefulness of fast protein liquid chromatography as an alternative to high performance liquid chromatography of 99mTc-labelled human serum albumin preparations.
Journal of pharmaceutical and biomedical analysis 1996;14(8-10):1209-13.
1996: Eugène Roets; P Rappe; M Heeren; J Hoebus; Alfons Verbruggen; Jos Hoogmartens
Investigation of the reaction mechanism of the mercurimetric determination of benzylpenicillin.
Journal of pharmaceutical and biomedical analysis 1996;14(8-10):1141-9.
1996: M Stoffel; François Jamar; C Van Nerom; Alfons Verbruggen; T Besse; Jean-Paul Squifflet; C Beckers
Technetium-99m L,L-ethylenedicysteine clearance and correlation with iodine-125 orthoiodohippurate for the determination of effective renal plasma flow.
European journal of nuclear medicine 1996;23(4):365-70.
1996: Hubert P Vanbilloen; MJ de Roo; Alfons Verbruggen
Complexes of technetium-99m with tetrapeptides containing one alanyl and three glycyl moieties.
European journal of nuclear medicine 1996;23(1):40-8.
1995: Y J Mortelmans; G Vermaut; Alfons Verbruggen; J M Arnout; J Vermylen; Hugo Van Aken; L A Mortelmans
Effects of 6% hydroxyethyl starch and 3% modified fluid gelatin on intravascular volume and coagulation during intraoperative hemodilution.
Anesthesia and analgesia 1995;81(6):1235-42.
1995: Kristin Verbeke; O Hjelstuen; E Debrock; Bernard J Cleynhens; MJ de Roo; Alfons Verbruggen
Comparative evaluation of 99Tcm-Hynic-HSA and 99Tcm-MAG3-HSA as possible blood pool agents.
Nuclear medicine communications 1995;16(11):942-57.
1995: K O Mang'era; Hubert P Vanbilloen; Christiaan Schiepers; Alfons Verbruggen
Stabilisation of high-activity 99mTc-d,l-HMPAO preparations with cobalt chloride and their biological behaviour.
European journal of nuclear medicine 1995;22(10):1163-72.
1995: Y Mortelmans; E Merckx; C van Nerom; Alfons Verbruggen; H van Aken; MJ de Roo; Luc Mortelmans
Effect of an equal volume replacement with 500 mL 6% hydroxyethyl starch on the blood and plasma volume of healthy volunteers.
European journal of anaesthesiology 1995;12(3):259-64.
1995: Guy Bormans; Bernard J Cleynhens; P Adriaens; Hubert P Vanbilloen; MJ de Roo; Alfons Verbruggen
Investigation of the labelling characteristics of 99mTc-mercaptoacetyltriglycine.
Nuclear medicine and biology 1995;22(3):339-49.
1995: Hubert P Vanbilloen; Guy Bormans; MJ de Roo; Alfons Verbruggen
Complexes of technetium-99m with tetrapeptides, a new class of 99mTc-labelled agents.
Nuclear medicine and biology 1995;22(3):325-38.
1995: L A Mortelmans; F J Wackers; Johan Nuyts; I A Scheys; T Brzostek; Christiaan Schiepers; E E Lesaffre; Paul Suetens; Alfons Verbruggen; Frans Van de Werf
Tomographic and planar quantitation of perfusion defects on technetium 99m-labeled sestamibi scans: evaluation in patients treated with thrombolytic therapy for acute myocardial infarction.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 1995;2(2 Pt 1):133-43.
1995: Guy Bormans; Alex Maes; W Langendries; Johan Nuyts; Mathias Vrolix; Johan Vanhaecke; Christiaan Schiepers; MJ de Roo; Luc Mortelmans; Alfons Verbruggen
Metabolism of nitrogen-13 labelled ammonia in different conditions in dogs, human volunteers and transplant patients.
European journal of nuclear medicine 1995;22(2):116-21.
1994: M Stoffel; François Jamar; C Van Nerom; Alfons Verbruggen; Michel Mourad; Norbert Leners; Jean-Paul Squifflet; C Beckers
Evaluation of technetium-99m-L,L-EC in renal transplant recipients: a comparative study with technetium-99m-MAG3 and iodine-125-OIH.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1994;35(12):1951-8.
1994: E Krznaric; André Nevelsteen; L van Hoe; MJ de Roo; Christiaan Schiepers; Alfons Verbruggen; Luc Mortelmans
Diagnostic value of 99Tcm-d,l-HMPAO-labelled leukocyte scintigraphy in the detection of vascular graft infections.
Nuclear medicine communications 1994;15(12):953-60.
1994: Kristin Verbeke; S Ons; MJ de Roo; Alfons Verbruggen
Labelling of poly-L-lysine with 99mTc and evaluation as a possible tracer agent for ventriculography.
Journal of nuclear biology and medicine (Turin, Italy : 1991) 1994;38(4 Suppl 1):75-8.
1994: Bernard J Cleynhens; P Adriaens; C Boonen; Hubert P Vanbilloen; C Van Nerom; Alfons Verbruggen
Synthesis and biological evaluation of the four isomers of 99mTc-cysteinyltriglycine, an amino substituted derivative of 99mTc-MAG3.
Journal of nuclear biology and medicine (Turin, Italy : 1991) 1994;38(4 Suppl 1):69-74.
1994: E Merckx; Christiaan Schiepers; Alfons Verbruggen; J Janssens; MJ de Roo
Brain perfusion scintigraphy with Tc-99m ethylcysteinate dimer for migraine accompagnée.
Clinical nuclear medicine 1994;19(10):922-3.
1994: Kristin Verbeke; W B Vanhecke; L A Mortelmans; Alfons Verbruggen
First evaluation of technetium-99m dimercaptopropionyl albumin as a possible tracer agent for ventriculography in a volunteer.
European journal of nuclear medicine 1994;21(9):906-12.
1993: Luc Mortelmans; Johan Nuyts; I Scheys; F Wackers; E Lesaffre; T Brzostek; MJ de Roo; H De Geest; Paul Suetens; Alfons Verbruggen
A new quantitative method for the analysis of cardiac perfusion tomography (SPET): validation in post-infarct patients treated with thrombolytic therapy.
European journal of nuclear medicine 1993;20(12):1193-200.
1993: C G Van Nerom; Guy Bormans; MJ de Roo; Alfons Verbruggen
First experience in healthy volunteers with technetium-99m L,L-ethylenedicysteine, a new renal imaging agent.
European journal of nuclear medicine 1993;20(9):738-46.
1993: Luc Mortelmans; Johan Nuyts; Johan Vanhaecke; Alfons Verbruggen; MJ de Roo; H De Geest; P Svetens; Frans Van de Werf
Experimental validation of a new quantitative method for the analysis of infarct size by cardiac perfusion tomography (SPECT).
International journal of cardiac imaging 1993;9(3):201-12.
1993: Kristin Verbeke; Hubert P Vanbilloen; MJ de Roo; Alfons Verbruggen
Technetium-99m mercaptoalbumin as a potential substitute or technetium-99m labelled red blood cells.
European journal of nuclear medicine 1993;20(6):473-82.
1993: Hubert P Vanbilloen; Kristin Verbeke; MJ de Roo; Alfons Verbruggen
Technetium-99m labelled human serum albumin for ventriculography: a comparative evaluation of six labelling kits.
European journal of nuclear medicine 1993;20(6):465-72.
1992: Alfons Verbruggen; D L Nosco; C G Van Nerom; Guy Bormans; P J Adriaens; MJ de Roo
Technetium-99m-L,L-ethylenedicysteine: a renal imaging agent. I. Labeling and evaluation in animals.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1992;33(4):551-7.
1992: Guy Bormans; Bernard J Cleynhens; M Hoogmartens; MJ de Roo; Alfons Verbruggen
Evaluation of 99mTc-mercaptoacetyltripeptides in mice and a baboon.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1992;19(3):375-88.
1992: Guy Bormans; B J Cleynhen; MJ de Roo; Alfons Verbruggen
Evaluation of the renal excretion characteristics of technetium-99m mercaptoacetylglycyl-D-alanylglycine in healthy volunteers.
European journal of nuclear medicine 1992;19(4):271-7.
1990: Alfons Verbruggen
Radiopharmaceuticals: state of the art.
European journal of nuclear medicine 1990;17(6-8):346-64.
1990: H Verlooy; Luc Mortelmans; Alfons Verbruggen; Jos Stuyck; M Boogaerts; MJ de Roo
Tc-99m HM-PAO labelled leucocyte scanning for detection of infection in orthopedic surgery.
Progress in clinical and biological research 1990;355():181-7.
1990: Guy Bormans; Bernard J Cleynhens; D José; M Hoogmartens; MJ de Roo; Alfons Verbruggen
Synthesis and biological characteristics of the four stereoisomers of 99mTc-N,N'-bis-(mercaptoacetyl)-2,3-diaminopropanoate.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1990;17(5):499-506.
1989: Luc Mortelmans; S Malbrain; Jos Stuyck; C De Backker; M J Heynen; M Boogaerts; MJ de Roo; Alfons Verbruggen
In vitro and in vivo evaluation of granulocyte labeling with [99mTc]d,1-HM-PAO.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1989;30(12):2022-8.
1989: Luc Mortelmans; Alfons Verbruggen; J Augustinus; Guido Wilms; MJ de Roo
Clinical usefulness of technetium-99m HM-PAO labeled white blood cell imaging in abscesses.
Clinical nuclear medicine 1989;14(2):127-9.
1989: MJ de Roo; Luc Mortelmans; P Devos; Alfons Verbruggen; Guido Wilms; H Carton; V Wils; R Van den Bergh
Clinical experience with Tc-99m HM-PAO high resolution SPECT of the brain in patients with cerebrovascular accidents.
European journal of nuclear medicine 1989;15(1):9-15.
1989: C van Nerom; Guy Bormans; Bernard J Cleynhens; MJ de Roo; Alfons Verbruggen
A convenient configuration for safe and efficient radio-HPLC of 99mTc-radiopharmaceuticals.
Journal of pharmaceutical and biomedical analysis 1989;7(12):1849-52.
1988: Luc Mortelmans; Alfons Verbruggen; S Malbrain; M J Heynen; C de Bakker; M Boogaerts; MJ de Roo
Evaluation of 111In labelled white blood cells by in vitro functional tests and electron microscopy. Comparison of three labelling methods.
European journal of nuclear medicine 1988;14(3):159-64.