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Bruce Verchere

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Xiaojie Wang; Noushin Akhoundsadegh; Ziliang Ao; Lieping Chen; Jianqiang Hao; I-Fang Lee; Daniel L Metzger; Alice L-F Mui; Dawei Ou; C Bruce Verchere; Garth L Warnock
Endogenous expression of B7-H4 improves long-term murine islet allograft survival.
Xiaojie Wang; Noushin Akhoundsadegh; Ziliang Ao; C Lieping Chen; Jianqiang Hao; I-Fang Lee; Daniel L Metzger; Alice Mui; Dawei Ou; C Bruce Verchere; Garth L Warnock
Blockade of both B7-H4 and CTLA-4 co-signaling pathways enhances mouse islet allograft survival.
Cristina Alarcon; C Bruce Verchere; Christopher J Rhodes
Translational control of glucose-induced islet amyloid polypeptide production in pancreatic islets.

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2013: Xiaojie Wang; Noushin Akhoundsadegh; Ziliang Ao; Lieping Chen; Jianqiang Hao; I-Fang Lee; Daniel L Metzger; Alice L-F Mui; Dawei Ou; C Bruce Verchere; Garth L Warnock
Endogenous expression of B7-H4 improves long-term murine islet allograft survival.
Transplantation 2013;95(1):94-9.
2012: Xiaojie Wang; Noushin Akhoundsadegh; Ziliang Ao; C Lieping Chen; Jianqiang Hao; I-Fang Lee; Daniel L Metzger; Alice Mui; Dawei Ou; C Bruce Verchere; Garth L Warnock
Blockade of both B7-H4 and CTLA-4 co-signaling pathways enhances mouse islet allograft survival.
Islets 2012;4(4):284-95.
2012: Cristina Alarcon; C Bruce Verchere; Christopher J Rhodes
Translational control of glucose-induced islet amyloid polypeptide production in pancreatic islets.
Endocrinology 2012;153(5):2082-7.
2012: Nadeeja Wijesekara; Lin-hua Zhang; Thomas Abraham; Alpana Bhattacharjee; Martin H Kang; C Bruce Verchere; Garth L Warnock; Michael R Hayden
miR-33a modulates ABCA1 expression, cholesterol accumulation, and insulin secretion in pancreatic islets.
Diabetes 2012;61(3):653-8.
2012: Janine K Kruit; Dieter Lütjohann; Renmei Tang; Tim Vanmierlo; C Bruce Verchere; Cheryl L Wellington; Clara Westwell-Roper; Nadeeja Wijesekara; Alpana Bhattacharjee; Liam R Brunham; Willeke de Haan; James D Johnson; Michael R Hayden
Loss of both ABCA1 and ABCG1 results in increased disturbances in islet sterol homeostasis, inflammation, and impaired β-cell function.
Diabetes 2012;61(3):659-64.
2012: Xiaojie Wang; Ziliang Ao; Lieping Chen; Jianqiang Hao; Daniel L Metzger; Alice L-F Mui; Dawei Ou; C Bruce Verchere; Garth L Warnock
B7-H4 induces donor-specific tolerance in mouse islet allografts.
Cell transplantation 2012;21(1):99-111.
2011: Sanjoy Ghosh; Melissa B Glier; Dian C Sulistyoningrum; C Bruce Verchere; Angela M Devlin
Altered glutathione homeostasis in heart augments cardiac lipotoxicity associated with diet-induced obesity in mice.
The Journal of biological chemistry 2011;286(49):42483-93.
2011: J Bailey; Leah Edelstein-keshet; K J Potter; C Bruce Verchere; D Coombs
Reverse engineering an amyloid aggregation pathway with dimensional analysis and scaling.
Physical biology 2011;8(6):066009.
2011: Janine K Kruit; Peter E Light; Patrick E MacDonald; Brad J Marsh; Garry P Morgan; Gavin J Searle; Renmei Tang; C Bruce Verchere; Nadeeja Wijesekara; Alpana Bhattacharjee; Liam R Brunham; Adam J Costin; Xiao-Qing Dai; Jocelyn E Manning Fox; James D Johnson; Michael R Hayden
Islet cholesterol accumulation due to loss of ABCA1 leads to impaired exocytosis of insulin granules.
Diabetes 2011;60(12):3186-96.
2011: Xiaojie Wang; Noushin Akhoundsadegh; Ziliang Ao; Lieping Chen; Jianqiang Hao; Solomon Langermann; Linda Liu; Daniel L Metzger; Alice Mui; Dawei Ou; C Bruce Verchere; Garth L Warnock
Early treatment of NOD mice with B7-H4 reduces the incidence of autoimmune diabetes.
Diabetes 2011;60(12):3246-55.
2011: Clara Westwell-Roper; Derek L Dai; Jan A Ehses; Kathryn J Potter; Galina Soukhatcheva; Nico van Rooijen; C Bruce Verchere
IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(5):2755-65.
2011: Joel Montane; Paul C Orban; Galina Soukhatcheva; Rusung Tan; Loraine Bischoff; Derek L Dai; Gijs Hardenberg; Timothy J Kieffer; Megan K Levings; C Bruce Verchere
Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets.
The Journal of clinical investigation 2011;121(8):3024-8.
2011: Marta Szabat; C Bruce Verchere; Garth L Warnock; James M Piret; Poya Pourghaderi; Galina Soukhatcheva; James D Johnson
Kinetics and genomic profiling of adult human and mouse β-cell maturation.
Islets 2011;3(4):175-87.
2011: Xiaojie Wang; Mark Meloche; Alice L-F Mui; Dawei Ou; C Bruce Verchere; Garth L Warnock
Improving islet engraftment by gene therapy.
Journal of transplantation 2011;2011():594851.
2011: Xiaojie Wang; Ziliang Ao; Lieping Chen; Jianqiang Hao; Mark Meloche; Daniel L Metzger; Alice L-F Mui; Dawei Ou; C Bruce Verchere; Garth L Warnock
B7-H4 Pathway in Islet Transplantation and β-Cell Replacement Therapies.
Journal of transplantation 2011;2011():418902.
2010: Fanling Meng; Andisheh Abedini; Annette Plesner; C Bruce Verchere; Daniel P Raleigh
The flavanol (-)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP-induced toxicity.
Biochemistry 2010;49(37):8127-33.
2010: Brad G Hoffman; Gordon Robertson; Bogard Zavaglia; Mike Beach; Rebecca Cullum; Sam Lee; Galina Soukhatcheva; Leping Li; Elizabeth D Wederell; Nina Thiessen; Mikhail Bilenky; Timothee Cezard; Angela Tam; Baljit Kamoh; Inanc Birol; Derek Dai; Yongjun Zhao; Martin Hirst; C Bruce Verchere; Cheryl D Helgason; Marco A Marra; Steven J M Jones; Pamela A Hoodless
Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver.
Genome research 2010;20(8):1037-51.
2010: Fanling Meng; Andisheh Abedini; Annette Plesner; Chris T Middleton; Kathryn J Potter; Martin T Zanni; C Bruce Verchere; Daniel P Raleigh
The sulfated triphenyl methane derivative acid fuchsin is a potent inhibitor of amyloid formation by human islet amyloid polypeptide and protects against the toxic effects of amyloid formation.
Journal of molecular biology 2010;400(3):555-66.
2010: Janine K Kruit; Liam R Brunham; C Bruce Verchere; Michael R Hayden
HDL and LDL cholesterol significantly influence beta-cell function in type 2 diabetes mellitus.
Current opinion in lipidology 2010;21(3):178-85.
2010: Janine K Kruit; P H C Kremer; L Dai; R Tang; P Ruddle; W de Haan; Liam R Brunham; C Bruce Verchere; Michael R Hayden
Cholesterol efflux via ATP-binding cassette transporter A1 (ABCA1) and cholesterol uptake via the LDL receptor influences cholesterol-induced impairment of beta cell function in mice.
Diabetologia 2010;53(6):1110-9.
2010: Sakeneh Zraika; Rebecca L Hull; C Bruce Verchere; A Clark; K J Potter; Paul E Fraser; D P Raleigh; Steven E Kahn
Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence?
Diabetologia 2010;53(6):1046-56.
2010: Menno Vergeer; Liam R Brunham; Joris Koetsveld; Janine K Kruit; C Bruce Verchere; John J P Kastelein; Michael R Hayden; Erik S G Stroes
Carriers of loss-of-function mutations in ABCA1 display pancreatic beta-cell dysfunction.
Diabetes care 2010;33(4):869-74.
2010: K J Potter; A Abedini; P Marek; Agnieszka Klimek; S Butterworth; M Driscoll; R Baker; M R Nilsson; Garth L Warnock; José Oberholzer; S Bertera; Massimo Trucco; G S Korbutt; Paul E Fraser; D P Raleigh; C Bruce Verchere
Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(9):4305-10.
2010: Meredith J H Hutton; Galina Soukhatcheva; James D Johnson; C Bruce Verchere
Role of the TLR signaling molecule TRIF in β-cell function and glucose homeostasis.
Islets 2010;2(2):104-11.
2010: Liam R Brunham; Janine K Kruit; Michael R Hayden; C Bruce Verchere
Cholesterol in beta-cell dysfunction: the emerging connection between HDL cholesterol and type 2 diabetes.
Current diabetes reports 2010;10(1):55-60.
2010: Peter T W Kim; Brad G Hoffman; Annette Plesner; Cheryl D Helgason; C Bruce Verchere; Stephen W Chung; Garth L Warnock; Alice L-F Mui; Christopher J Ong
Differentiation of mouse embryonic stem cells into endoderm without embryoid body formation.
PloS one 2010;5(11):e14146.
2010: Annette Plesner; Galina Soukhatcheva; Robert G Korneluk; C Bruce Verchere
XIAP inhibition of β-cell apoptosis reduces the number of islets required to restore euglycemia in a syngeneic islet transplantation model.
Islets 2010;2(1):18-23.
2009: Meredith J H Hutton; Clara Westwell-Roper; Galina Soukhatcheva; Annette Plesner; Jan P Dutz; C Bruce Verchere
Islet allograft rejection is independent of toll-like receptor signaling in mice.
Transplantation 2009;88(9):1075-80.
2009: Agnieszka Klimek; G Soukhatcheva; David M Thompson; Garth L Warnock; M Salehi; H Rilo; D D'Alessio; Graydon S Meneilly; Constadina Panagiotopoulos; C Bruce Verchere
Impaired proinsulin processing is a characteristic of transplanted islets.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2009;9(9):2119-25.
2009: Kathryn J Potter; Louise A Scrocchi; Garth L Warnock; Ziliang Ao; Marika A Younker; Lawrence Rosenberg; Mark Lipsett; C Bruce Verchere; Paul E Fraser
Amyloid inhibitors enhance survival of cultured human islets.
Biochimica et biophysica acta 2009;1790(6):566-74.
2009: Xiaojie Wang; Jianqiang Hao; Daniel L Metzger; Alice L-F Mui; Ziliang Ao; C Bruce Verchere; Lieping Chen; Dawei Ou; Garth L Warnock
Local expression of B7-H4 by recombinant adenovirus transduction in mouse islets prolongs allograft survival.
Transplantation 2009;87(4):482-90.
2009: James D Johnson; Ziliang Ao; Peter Ao; Hong Li; Long-Jun Dai; Zehua He; May Tee; Kathryn J Potter; Agnieszka Klimek; R Mark Meloche; David M Thompson; C Bruce Verchere; Garth L Warnock
Different effects of FK506, rapamycin, and mycophenolate mofetil on glucose-stimulated insulin release and apoptosis in human islets.
Cell transplantation 2009;18(8):833-45.
2008: Garth L Warnock; David M Thompson; R Mark Meloche; R Jean Shapiro; Ziliang Ao; Paul Keown; James D Johnson; C Bruce Verchere; Nilufar Partovi; Iain S Begg; Michelle Fung; Sharon E Kozak; Suet On Tong; Khalid M Alghofaili; Claire Harris
A multi-year analysis of islet transplantation compared with intensive medical therapy on progression of complications in type 1 diabetes.
Transplantation 2008;86(12):1762-6.
2008: Lucy Marzban; Alejandra Tomas; Thomas C Becker; Lawrence Rosenberg; José Oberholzer; Paul E Fraser; Philippe A Halban; C Bruce Verchere
Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture.
Diabetes 2008;57(11):3045-55.
2008: Fanling Meng; Peter Marek; Kathryn J Potter; C Bruce Verchere; Daniel P Raleigh
Rifampicin does not prevent amyloid fibril formation by human islet amyloid polypeptide but does inhibit fibril thioflavin-T interactions: implications for mechanistic studies of beta-cell death.
Biochemistry 2008;47(22):6016-24.
2008: Liam R Brunham; Janine K Kruit; C Bruce Verchere; Michael R Hayden
Cholesterol in islet dysfunction and type 2 diabetes.
The Journal of clinical investigation 2008;118(2):403-8.
2007: Garth L Warnock; Yu-Huan Theresa Liao; Xiaojie Wang; Dawei Ou; Ziliang Ao; James D Johnson; C Bruce Verchere; David Thompson
An odyssey of islet transplantation for therapy of type 1 diabetes.
World journal of surgery 2007;31(8):1569-76.
2007: Jacqueline D Trudeau; T Chandler; G Soukhatcheva; C Bruce Verchere; R Tan
Prospective prediction of spontaneous but not recurrent autoimmune diabetes in the non-obese diabetic mouse.
Diabetologia 2007;50(5):1015-23.
2007: Yu-Huan Theresa Liao; C Bruce Verchere; Garth L Warnock
Adult stem or progenitor cells in treatment for type 1 diabetes: current progress.
Canadian journal of surgery. Journal canadien de chirurgie 2007;50(2):137-42.
2007: Liam R Brunham; Janine K Kruit; Terry D Pape; Jenelle M Timmins; Anne Q Reuwer; Zainisha Vasanji; Brad J Marsh; Brian Rodrigues; James D Johnson; John S Parks; C Bruce Verchere; Michael R Hayden
Beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment.
Nature medicine 2007;13(3):340-7.
2007: J T Wong; Peter T W Kim; James W Peacock; T Y Yau; Alice L-F Mui; Stephen W Chung; Vesna Sossi; Doris J Doudet; D Green; Thomas J Ruth; R Parsons; C Bruce Verchere; Christopher J Ong
Pten (phosphatase and tensin homologue gene) haploinsufficiency promotes insulin hypersensitivity.
Diabetologia 2007;50(2):395-403.
2006: Qin Ouyang; Nathan E Standifer; Huilian Qin; Peter Gottlieb; C Bruce Verchere; Gerald Nepom; Rusung Tan; Constadina Panagiotopoulos
Recognition of HLA class I-restricted beta-cell epitopes in type 1 diabetes.
Diabetes 2006;55(11):3068-74.
2006: Nathan E Standifer; Qin Ouyang; Constadina Panagiotopoulos; C Bruce Verchere; Rusung Tan; Carla J Greenbaum; Catherine Pihoker; Gerald Nepom
Identification of Novel HLA-A*0201-restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives.
Diabetes 2006;55(11):3061-7.
2006: Rhonda D Wideman; Irene L Y Yu; Travis D Webber; C Bruce Verchere; James D Johnson; Anthony T Cheung; Timothy J Kieffer
Improving function and survival of pancreatic islets by endogenous production of glucagon-like peptide 1 (GLP-1).
Proceedings of the National Academy of Sciences of the United States of America 2006;103(36):13468-73.
2006: Lucy Marzban; Christopher J Rhodes; Donald F Steiner; Leena Haataja; Philippe A Halban; C Bruce Verchere
Impaired NH2-terminal processing of human proislet amyloid polypeptide by the prohormone convertase PC2 leads to amyloid formation and cell death.
Diabetes 2006;55(8):2192-201.
2006: Anne E Mullin; Galina Soukatcheva; C Bruce Verchere; Janet Kathleen Chantler
Application of in situ ductal perfusion to facilitate isolation of high-quality RNA from mouse pancreas.
BioTechniques 2006;40(5):617-21.
2006: Daniel A Peters; C Bruce Verchere
Healing at home: Comparing cohorts of children with medium-sized burns treated as outpatients with in-hospital applied Acticoat to those children treated as inpatients with silver sulfadiazine.
Journal of burn care & research : official publication of the American Burn Association 2006;27(2):198-201.
2005: Annette Plesner; Peter Liston; Rusung Tan; Robert G Korneluk; C Bruce Verchere
The X-linked inhibitor of apoptosis protein enhances survival of murine islet allografts.
Diabetes 2005;54(9):2533-40.
2005: Garth L Warnock; R Mark Meloche; David Thompson; R Jean Shapiro; Michelle Fung; Ziliang Ao; Stephen Ho; Zehua He; Long-Jun Dai; Linnea Young; Lorraine Blackburn; Sharon E Kozak; Peter T W Kim; David Al-Adra; James D Johnson; Yu-Huan Theresa Liao; Tom Elliott; C Bruce Verchere
Improved human pancreatic islet isolation for a prospective cohort study of islet transplantation vs best medical therapy in type 1 diabetes mellitus.
Archives of surgery (Chicago, Ill. : 1960) 2005;140(8):735-44.
2005: Lucy Marzban; Genny Trigo-Gonzalez; C Bruce Verchere
Processing of pro-islet amyloid polypeptide in the constitutive and regulated secretory pathways of beta cells.
Molecular endocrinology (Baltimore, Md.) 2005;19(8):2154-63.
2005: Lucy Marzban; Galina Soukhatcheva; C Bruce Verchere
Role of carboxypeptidase E in processing of pro-islet amyloid polypeptide in {beta}-cells.
Endocrinology 2005;146(4):1808-17.
2005: Dawei Ou; Xiaojie Wang; Daniel L Metzger; Roger F L James; Paolo Pozzilli; Annette Plesner; Robert G Korneluk; C Bruce Verchere; Aubrey J Tingle
Synergistic inhibition of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human pancreatic beta cells by Bcl-2 and X-linked inhibitor of apoptosis.
Human immunology 2005;66(3):274-84.
2004: Huilian Qin; Jacqueline D Trudeau; Gregor S D Reid; I-Fang Lee; Jan P Dutz; Pere Santamaria; C Bruce Verchere; Rusung Tan
Progression of spontaneous autoimmune diabetes is associated with a switch in the killing mechanism used by autoreactive CTL.
International immunology 2004;16(11):1657-62.
2004: Sofianos Andrikopoulos; Rebecca L Hull; C Bruce Verchere; Feng Wang; Shani M Wilbur; Thomas N Wight; Lucy Marzban; Steven E Kahn
Extended life span is associated with insulin resistance in a transgenic mouse model of insulinoma secreting human islet amyloid polypeptide.
American journal of physiology. Endocrinology and metabolism 2004;286(3):E418-24.
2004: Lucy Marzban; Genny Trigo-Gonzalez; Xiaorong Zhu; Christopher J Rhodes; Philippe A Halban; Donald F Steiner; C Bruce Verchere
Role of beta-cell prohormone convertase (PC)1/3 in processing of pro-islet amyloid polypeptide.
Diabetes 2004;53(1):141-8.
2003: Constadina Panagiotopoulos; Huilian Qin; Rusung Tan; C Bruce Verchere
Identification of a beta-cell-specific HLA class I restricted epitope in type 1 diabetes.
Diabetes 2003;52(11):2647-51.
2003: Lucy Marzban; Kirily Park; C Bruce Verchere
Islet amyloid polypeptide and type 2 diabetes.
Experimental gerontology 2003;38(4):347-51.
2003: Rebecca L Hull; Sofianos Andrikopoulos; C Bruce Verchere; Josep Vidal; Feng Wang; Miriam Cnop; Ronald L Prigeon; Steven E Kahn
Increased dietary fat promotes islet amyloid formation and beta-cell secretory dysfunction in a transgenic mouse model of islet amyloid.
Diabetes 2003;52(2):372-9.
2003: Josep Vidal; C Bruce Verchere; Sofianos Andrikopoulos; Feng Wang; Rebecca L Hull; Miriam Cnop; Katherine L Olin; R C LeBoeuf; Kevin D O'Brien; Alan Chait; Steven E Kahn
The effect of apolipoprotein E deficiency on islet amyloid deposition in human islet amyloid polypeptide transgenic mice.
Diabetologia 2003;46(1):71-9.
2003: Jacqueline D Trudeau; Carolyn Kelly-Smith; C Bruce Verchere; John Elliott; Jan P Dutz; Diane T Finegood; Pere Santamaria; Rusung Tan
Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood.
The Journal of clinical investigation 2003;111(2):217-23.
2002: Yasmin Pirani; Wendy G Cannon; C Bruce Verchere
A discovery of real medicine.
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2002;15(4):181-2.
2001: K Park; C Bruce Verchere
Identification of a heparin binding domain in the N-terminal cleavage site of pro-islet amyloid polypeptide. Implications for islet amyloid formation.
The Journal of biological chemistry 2001;276(20):16611-6.
2001: J Wang; J Xu; J Finnerty; M Furuta; Donald F Steiner; C Bruce Verchere
The prohormone convertase enzyme 2 (PC2) is essential for processing pro-islet amyloid polypeptide at the NH2-terminal cleavage site.
Diabetes 2001;50(3):534-9.
2001: Rebecca L Hull; C Bruce Verchere; Sofianos Andrikopoulos; Feng Wang; Josep Vidal; Steven E Kahn
Oophorectomy promotes islet amyloid formation in human islet amyloid polypeptide transgenic mice.
Diabetes 2001;50 Suppl 1():S184-5.
2000: Sofianos Andrikopoulos; C Bruce Verchere; Y Terauchi; T Kadowaki; Steven E Kahn
beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes.
Diabetes 2000;49(12):2056-62.
2000: Steven E Kahn; Sofianos Andrikopoulos; C Bruce Verchere; Feng Wang; Rebecca L Hull; Josep Vidal
Oophorectomy promotes islet amyloid formation in a transgenic mouse model of Type II diabetes.
Diabetologia 2000;43(10):1309-12.
2000: C Bruce Verchere; David A D'Alessio; Ronald L Prigeon; Rebecca L Hull; Steven E Kahn
The constitutive secretory pathway is a major route for islet amyloid polypeptide secretion in neonatal but not adult rat islet cells.
Diabetes 2000;49(9):1477-84.
1999: Sofianos Andrikopoulos; C Bruce Verchere; Jeanette C Teague; W M Howell; Wilfred Y Fujimoto; Thomas N Wight; Steven E Kahn
Two novel immortal pancreatic beta-cell lines expressing and secreting human islet amyloid polypeptide do not spontaneously develop islet amyloid.
Diabetes 1999;48(10):1962-70.
1999: A N Demianczuk; C Bruce Verchere; J H Phillips
The effect on facial growth of pediatric mandibular fractures.
The Journal of craniofacial surgery 1999;10(4):323-8.
1999: Gerald J Taborsky; B E Dunning; P J Havel; B Ahren; S Kowalyk; MR Boyle; C Bruce Verchere; Denis Baskin; Thomas O Mundinger
The canine sympathetic neuropeptide galanin: a neurotransmitter in pancreas, a neuromodulator in liver.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1999;31(5):351-4.
1999: Steven E Kahn; Sofianos Andrikopoulos; C Bruce Verchere
Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes.
Diabetes 1999;48(2):241-53.
1998: C J Dechenes; C Bruce Verchere; Sofianos Andrikopoulos; Steven E Kahn
Human aging is associated with parallel reductions in insulin and amylin release.
The American journal of physiology 1998;275(5 Pt 1):E785-91.
1998: K M Kadesky; Casey R A Manarey; Geoffrey K Blair; James J Murphy; C Bruce Verchere; K Atkinson
Cougar attacks on children: injury patterns and treatment.
Journal of pediatric surgery 1998;33(6):863-5.
1998: Steven E Kahn; C Bruce Verchere; Sofianos Andrikopoulos; Pamela J Asberry; Donna L Leonetti; PW Wahl; Edward J Boyko; Robert S Schwartz; Laura Newell-Morris; Wilfred Y Fujimoto
Reduced amylin release is a characteristic of impaired glucose tolerance and type 2 diabetes in Japanese Americans.
Diabetes 1998;47(4):640-5.
1997: Thomas O Mundinger; C Bruce Verchere; Denis Baskin; MR Boyle; S Kowalyk; Gerald J Taborsky
Galanin is localized in sympathetic neurons of the dog liver.
The American journal of physiology 1997;273(6 Pt 1):E1194-202.
1997: Jean-Claude Irminger; C Bruce Verchere; K Meyer; Philippe A Halban
Proinsulin targeting to the regulated pathway is not impaired in carboxypeptidase E-deficient Cpefat/Cpefat mice.
The Journal of biological chemistry 1997;272(44):27532-4.
1997: Romano Regazzi; C Bruce Verchere; Philippe A Halban; Kenneth S Polonsky
Insulin production: from gene to granule.
Diabetologia 1997;40 Suppl 3():B33-8.
1997: Peter J Havel; B E Dunning; C Bruce Verchere; Denis Baskin; T O'Dorisio; Gerald J Taborsky
Evidence that vasoactive intestinal polypeptide is a parasympathetic neurotransmitter in the endocrine pancreas in dogs.
Regulatory peptides 1997;71(3):163-70.
1997: C Bruce Verchere; David A D'Alessio; S Wang; Sofianos Andrikopoulos; S E Kahn
Transgenic overproduction of islet amyloid polypeptide (amylin) is not sufficient for islet amyloid formation.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1997;29(6):311-6.
1996: C Bruce Verchere; S Kowalyk; D J Koerker; Denis Baskin; Gerald J Taborsky
Evidence that galanin is a parasympathetic, rather than a sympathetic, neurotransmitter in the baboon pancreas.
Regulatory peptides 1996;67(2):93-101.
1996: C Bruce Verchere; M Paoletta; Marguerite Neerman-Arbez; K Rose; Jean-Claude Irminger; R L Gingerich; Steven E Kahn; Philippe A Halban
Des-(27-31)C-peptide. A novel secretory product of the rat pancreatic beta cell produced by truncation of proinsulin connecting peptide in secretory granules.
The Journal of biological chemistry 1996;271(44):27475-81.
1996: C Bruce Verchere; David A D'Alessio; Richard D Palmiter; G C Weir; S Bonner-Weir; Denis Baskin; Steven E Kahn
Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(8):3492-6.
1994: David A D'Alessio; C Bruce Verchere; Steven E Kahn; V Hoagland; Denis Baskin; Richard D Palmiter; J W Ensinck
Pancreatic expression and secretion of human islet amyloid polypeptide in a transgenic mouse.
Diabetes 1994;43(12):1457-61.
1994: C Bruce Verchere; S Kowalyk; G H Shen; M R Brown; Michael W Schwartz; Denis Baskin; Gerald J Taborsky
Major species variation in the expression of galanin messenger ribonucleic acid in mammalian celiac ganglion.
Endocrinology 1994;135(3):1052-9.
1994: C Bruce Verchere; David A D'Alessio; Richard D Palmiter; Steven E Kahn
Transgenic mice overproducing islet amyloid polypeptide have increased insulin storage and secretion in vitro.
Diabetologia 1994;37(7):725-8.
1994: M R Boyle; C Bruce Verchere; G McKnight; S Mathews; K Walker; Gerald J Taborsky
Canine galanin: sequence, expression and pancreatic effects.
Regulatory peptides 1994;50(1):1-11.
1994: J Wang; C Bruce Verchere; Christopher H S McIntosh; J C Brown
Characterization of acetylcholine-induced increases in cytosolic free calcium concentration in individual rat pancreatic beta-cells.
Cell adhesion and communication 1994;1(4):343-53.
1993: T J Kieffer; C Bruce Verchere; C D Fell; Z Huang; J C Brown; R A Pedersen
Glucose-dependent insulinotropic polypeptide stimulated insulin release from a tumor-derived beta-cell line (beta TC3).
Canadian journal of physiology and pharmacology 1993;71(12):917-22.
1993: Steven E Kahn; C Bruce Verchere; David A D'Alessio; D L Cook; Wilfred Y Fujimoto
Evidence for selective release of rodent islet amyloid polypeptide through the constitutive secretory pathway.
Diabetologia 1993;36(6):570-3.
1993: C Bruce Verchere; Y N Kwok; J C Brown
Inhibitory actions of a somatostatin analog SMS 201-995 on endocrine secretion from the isolated perfused stomach and pancreas of the rat.
Pharmacology 1993;46(1):50-60.
1992: C Bruce Verchere; Y N Kwok; J C Brown
Stimulus-specific inhibition of insulin release from rat pancreas by both rat and porcine galanin.
Life sciences 1992;51(25):1945-51.
1991: C Bruce Verchere; Y N Kwok; J C Brown
Modulation of acetylcholine-stimulated insulin release by glucose and gastric inhibitory polypeptide.
Pharmacology 1991;42(5):273-82.
1988: Y N Kwok; C Bruce Verchere; Christopher H S McIntosh; J C Brown
Effect of galanin on endocrine secretions from the isolated perfused rat stomach and pancreas.
European journal of pharmacology 1988;145(1):49-54.