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Nuria Verdaguer

Research Profile

Procedures

X Ray Crystallography

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Diego Ferrero; José F Rodriguez; Mònica Buxaderas; Nuria Verdaguer
Purification, crystallization and preliminary X-ray diffraction analysis of the RNA-dependent RNA polymerase from Thosea asigna virus.
Nuria Verdaguer; Cristina Ferrer-Orta
Conformational changes in motif D of RdRPs as fidelity determinant.
Daniel Luque; Roberto Marabini; Ignacio Mena; Benes Trus; Nuria Verdaguer; Iván Angulo; Juan Bárcena; José L Carrascosa; Javier Chichón; Josué Gómez-Blanco; José M González; Jose Caston
Epitope insertion at the N-terminal molecular switch of the rabbit hemorrhagic disease virus T = 3 capsid protein leads to larger T = 4 capsids.

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All Publications

2012: Diego Ferrero; José F Rodriguez; Mònica Buxaderas; Nuria Verdaguer
Purification, crystallization and preliminary X-ray diffraction analysis of the RNA-dependent RNA polymerase from Thosea asigna virus.
Acta crystallographica. Section F, Structural biology and crystallization communications 2012;68(Pt 10):1263-6.
2012: Nuria Verdaguer; Cristina Ferrer-Orta
Conformational changes in motif D of RdRPs as fidelity determinant.
Structure (London, England : 1993) 2012;20(9):1448-50.
2012: Daniel Luque; Roberto Marabini; Ignacio Mena; Benes Trus; Nuria Verdaguer; Iván Angulo; Juan Bárcena; José L Carrascosa; Javier Chichón; Josué Gómez-Blanco; José M González; Jose Caston
Epitope insertion at the N-terminal molecular switch of the rabbit hemorrhagic disease virus T = 3 capsid protein leads to larger T = 4 capsids.
Journal of virology 2012;86(12):6470-80.
2011: Damià Garriga; Sandra Macedo-Ribeiro; Pedro José Barbosa Pereira; Bruno Almeida; Mònica Buxaderas; Frederico Ferreira-da-Silva; Laia Vives-Adrián; Nuria Verdaguer
Cloning, purification and preliminary crystallographic studies of the 2AB protein from hepatitis A virus.
Acta crystallographica. Section F, Structural biology and crystallization communications 2011;67(Pt 10):1224-7.
2010: Daniel Luque; José M González; Damià Garriga; Said A Ghabrial; Wendy M Havens; Benes Trus; Nuria Verdaguer; José L Carrascosa; Jose Caston
The T=1 capsid protein of Penicillium chrysogenum virus is formed by a repeated helix-rich core indicative of gene duplication.
Journal of virology 2010;84(14):7256-66.
2009: Cristina Ferrer-Orta; Rubén Agudo; Esteban Domingo; Nuria Verdaguer
Structural insights into replication initiation and elongation processes by the FMDV RNA-dependent RNA polymerase.
Current opinion in structural biology 2009;19(6):752-8.
2009: Jordi Querol-Audí; Tuende Konecsni; joan pous; Oliviero Carugo; Ignacio Fita; Nuria Verdaguer; Dieter Blaas
Minor group human rhinovirus-receptor interactions: geometry of multimodular attachment and basis of recognition.
FEBS letters 2009;583(1):235-40.
2008: Arnau Casañas; Aitor Navarro Nieto; Cristina Ferrer-Orta; Dolores González; José F Rodríguez; Nuria Verdaguer
Structural insights into the multifunctional protein VP3 of birnaviruses.
Structure (London, England : 1993) 2008;16(1):29-37.
2007: Damià Garriga; Aitor Navarro Nieto; Jordi Querol-Audí; Fernando Abaitua; José F Rodríguez; Nuria Verdaguer
Activation mechanism of a noncanonical RNA-dependent RNA polymerase.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(51):20540-5.
2007: Daniel Luque; Irene Saugar; José F Rodríguez; Nuria Verdaguer; Damià Garriga; Carmen San Martín; Javier A Velázquez-Muriel; Benes Trus; José L Carrascosa; Jose Caston
Infectious bursal disease virus capsid assembly and maturation by structural rearrangements of a transient molecular switch.
Journal of virology 2007;81(13):6869-78.
2007: Cristina Ferrer-Orta; Armando Arias; Rosa Pérez-Luque; Cristina Escarmís; Esteban Domingo; Nuria Verdaguer
Sequential structures provide insights into the fidelity of RNA replication.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(22):9463-8.
2006: Damià Garriga; Jordi Querol-Audí; Fernando Abaitua; Irene Saugar; joan pous; Nuria Verdaguer; Jose Caston; José F Rodriguez
The 2.6-Angstrom structure of infectious bursal disease virus-derived T=1 particles reveals new stabilizing elements of the virus capsid.
Journal of virology 2006;80(14):6895-905.
2006: Cristina Ferrer-Orta; Armando Arias; Rubén Agudo; Rosa Pérez-Luque; Cristina Escarmís; Esteban Domingo; Nuria Verdaguer
The structure of a protein primer-polymerase complex in the initiation of genome replication.
The EMBO journal 2006;25(4):880-8.
2006: Cristina Ferrer-Orta; Armando Arias; Cristina Escarmís; Nuria Verdaguer
A comparison of viral RNA-dependent RNA polymerases.
Current opinion in structural biology 2006;16(1):27-34.
2005: Armando Arias; Rubén Agudo; Cristina Ferrer-Orta; Rosa Pérez-Luque; Antero Airaksinen; Emiliana Brocchi; Esteban Domingo; Nuria Verdaguer; Cristina Escarmís
Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA binding.
Journal of molecular biology 2005;353(5):1021-32.
2005: Jordi Querol-Audí; Rosa Perez-Luque; Ignacio Fita; Carmen Lopéz-Iglesias; Jose Caston; José L Carrascosa; Nuria Verdaguer
Preliminary analysis of two and three dimensional crystals of vault ribonucleoprotein particles.
Journal of structural biology 2005;151(1):111-5.
2004: Cristina Ferrer-Orta; Armando Arias; Rosa Perez-Luque; Cristina Escarmís; Esteban Domingo; Nuria Verdaguer
Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA.
The Journal of biological chemistry 2004;279(45):47212-21.
2004: Nuria Verdaguer; Ignacio Fita; Manuela Reithmayer; Rosita Moser; Dieter Blaas
X-ray structure of a minor group human rhinovirus bound to a fragment of its cellular receptor protein.
Nature structural & molecular biology 2004;11(5):429-34.
2004: Juan Bárcena; Nuria Verdaguer; Ramón Roca; Mónica Morales; Iván Angulo; Cristina Risco; José L Carrascosa; Juan M Torres; Jose Caston
The coat protein of Rabbit hemorrhagic disease virus contains a molecular switch at the N-terminal region facing the inner surface of the capsid.
Virology 2004;322(1):118-34.
2003: Cristina Horcajada; Emili Cid; Joan J Guinovart; Nuria Verdaguer; Juan C Ferrer
Crystallization and preliminary X-ray analysis of the glycogen synthase from Pyrococcus abyssi.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 12):2322-4.
2003: Nuria Verdaguer; Miguel A Jimenez-Clavero; Ignacio Fita; Victoria Ley
Structure of swine vesicular disease virus: mapping of changes occurring during adaptation of human coxsackie B5 virus to infect swine.
Journal of virology 2003;77(18):9780-9.
2003: Wendy F Ochoa; Alejandro Torrecillas; Ignacio Fita; Nuria Verdaguer; Senena Corbalan-Garcia; Juan C Gomez-Fernandez
Retinoic acid binds to the C2-domain of protein kinase C(alpha).
Biochemistry 2003;42(29):8774-9.
2003: Miguel A Jimenez-Clavero; Victoria Ley; Ignacio Fita; Nuria Verdaguer
Crystallization and preliminary X-ray analysis of swine vesicular disease virus (SVDV).
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 3):541-3.
2003: Eric Baranowski; Carmen M Ruiz-Jarabo; Nonia Pariente; Nuria Verdaguer; Esteban Domingo
Evolution of cell recognition by viruses: a source of biological novelty with medical implications.
Advances in virus research 2003;62():19-111.
2002: Wendy F Ochoa; Senena Corbalán-Garcia; Ramon Eritja; José A Rodríguez-Alfaro; Juan C Gómez-Fernández; Ignacio Fita; Nuria Verdaguer
Additional binding sites for anionic phospholipids and calcium ions in the crystal structures of complexes of the C2 domain of protein kinase calpha.
Journal of molecular biology 2002;320(2):277-91.
2002: P Gomes; Ernest Giralt; Wendy F Ochoa; Nuria Verdaguer; David Andreu
Probing degeneracy in antigen-antibody recognition at the immunodominant site of foot-and-mouth disease virus.
The journal of peptide research : official journal of the American Peptide Society 2002;59(5):221-31.
2001: Wendy F Ochoa; J Garcia-Garcia; Ignacio Fita; Senena Corbalan-Garcia; Nuria Verdaguer; Juan C Gomez-Fernandez
Structure of the C2 domain from novel protein kinase Cepsilon. A membrane binding model for Ca(2+)-independent C2 domains.
Journal of molecular biology 2001;311(4):837-49.
2001: Xavier Carpena; R Perez; Wendy F Ochoa; Nuria Verdaguer; Martin Klotz; Jack Switala; William Melik-Adamyan; Ignacio Fita; Peter C Loewen
Crystallization and preliminary X-ray analysis of clade I catalases from Pseudomonas syringae and Listeria seeligeri.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 8):1184-6.
2000: Nuria Verdaguer; Dieter Blaas; Ignacio Fita
Structure of human rhinovirus serotype 2 (HRV2).
Journal of molecular biology 2000;300(5):1179-94.
2000: Wendy F Ochoa; Susana G Kalko; Mauricio G Mateu; P Gomes; David Andreu; Esteban Domingo; Ignacio Fita; Nuria Verdaguer
A multiply substituted G-H loop from foot-and-mouth disease virus in complex with a neutralizing antibody: a role for water molecules.
The Journal of general virology 2000;81(Pt 6):1495-505.
2000: Susana G Kalko; Monica Chagoyen; N Jiménez-Lozano; Nuria Verdaguer; Ignacio Fita; J M Carazo
The need for a shared database infrastructure: combining X-ray crystallography and electron microscopy.
European biophysics journal : EBJ 2000;29(6):457-62.
1999: Nuria Verdaguer; Senena Corbalan-Garcia; Wendy F Ochoa; Ignacio Fita; Juan C Gómez-Fernández
Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine.
The EMBO journal 1999;18(22):6329-38.
1999: Esteban Domingo; Nuria Verdaguer; Wendy F Ochoa; Carmen M Ruiz-Jarabo; Noemí Sevilla; Eric Baranowski; Mauricio G Mateu; Ignacio Fita
Biochemical and structural studies with neutralizing antibodies raised against foot-and-mouth disease virus.
Virus research 1999;62(2):169-75.
1999: Nuria Verdaguer; TC Marlovits; J Bravo; D I Stuart; Dieter Blaas; Ignacio Fita
Crystallization and preliminary X-ray analysis of human rhinovirus serotype 2 (HRV2).
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 8):1459-61.
1999: Nuria Verdaguer; Guy Schoehn; Wendy F Ochoa; Ignacio Fita; S Brookes; A King; Esteban Domingo; Mauricio G Mateu; D Stuart; Elizabeth A Hewat
Flexibility of the major antigenic loop of foot-and-mouth disease virus bound to a Fab fragment of a neutralising antibody: structure and neutralisation.
Virology 1999;255(2):260-8.
1998: Cristina Escarmís; E C Carrillo; M Ferrer; J F Arriaza; N Lopez; C Tami; Nuria Verdaguer; Esteban Domingo; M T Franze-Fernández
Rapid selection in modified BHK-21 cells of a foot-and-mouth disease virus variant showing alterations in cell tropism.
Journal of virology 1998;72(12):10171-9.
1998: Eric Baranowski; Noemí Sevilla; Nuria Verdaguer; Carmen M Ruiz-Jarabo; E Beck; Esteban Domingo
Multiple virulence determinants of foot-and-mouth disease virus in cell culture.
Journal of virology 1998;72(8):6362-72.
1998: Nuria Verdaguer; Noemí Sevilla; M L Valero; D Stuart; Emiliana Brocchi; David Andreu; E Giralt; Esteban Domingo; Mauricio G Mateu; Ignacio Fita
A similar pattern of interaction for different antibodies with a major antigenic site of foot-and-mouth disease virus: implications for intratypic antigenic variation.
Journal of virology 1998;72(1):739-48.
1997: Nuria Verdaguer; Ignacio Fita; Esteban Domingo; Mauricio G Mateu
Efficient neutralization of foot-and-mouth disease virus by monovalent antibody binding.
Journal of virology 1997;71(12):9813-6.
1997: M A Martínez; Nuria Verdaguer; Mauricio G Mateu; Esteban Domingo
Evolution subverting essentiality: dispensability of the cell attachment Arg-Gly-Asp motif in multiply passaged foot-and-mouth disease virus.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(13):6798-802.
1997: Elizabeth A Hewat; Nuria Verdaguer; Ignacio Fita; W Blakemore; S Brookes; A King; J Newman; Esteban Domingo; Mauricio G Mateu; D I Stuart
Structure of the complex of an Fab fragment of a neutralizing antibody with foot-and-mouth disease virus: positioning of a highly mobile antigenic loop.
The EMBO journal 1997;16(7):1492-500.
1996: Noemí Sevilla; Nuria Verdaguer; Esteban Domingo
Antigenically profound amino acid substitutions occur during large population passages of foot-and-mouth disease virus.
Virology 1996;225(2):400-5.
1996: Alba Guarné; R Kirchweger; Nuria Verdaguer; Hans-Dieter Liebig; Dieter Blaas; Tim Skern; Ignacio Fita
Crystallization and preliminary X-ray diffraction studies of the Lb proteinase from foot-and-mouth disease virus.
Protein science : a publication of the Protein Society 1996;5(9):1931-3.
1996: Nuria Verdaguer; Mauricio G Mateu; J Bravo; E Domingo; Ignacio Fita
Induced pocket to accommodate the cell attachment Arg-Gly-Asp motif in a neutralizing antibody against foot-and-mouth-disease virus.
Journal of molecular biology 1996;256(2):364-76.
1995: J Bravo; Nuria Verdaguer; J Tormo; C Betzel; Jack Switala; Peter C Loewen; Ignacio Fita
Crystal structure of catalase HPII from Escherichia coli.
Structure (London, England : 1993) 1995;3(5):491-502.
1995: Nuria Verdaguer; Mauricio G Mateu; David Andreu; Ernest Giralt; E Domingo; Ignacio Fita
Structure of the major antigenic loop of foot-and-mouth disease virus complexed with a neutralizing antibody: direct involvement of the Arg-Gly-Asp motif in the interaction.
The EMBO journal 1995;14(8):1690-6.
1995: M L Valero; Julio A Camarero; A Adeva; Nuria Verdaguer; Ignacio Fita; Mauricio G Mateu; Esteban Domingo; Ernest Giralt; David Andreu
Cyclic peptides as conformationally restricted models of viral antigens: application to foot-and-mouth disease virus.
Biomedical peptides, proteins & nucleic acids : structure, synthesis & biological activity 1995;1(3):133-40.
1995: Esteban Domingo; Mauricio G Mateu; Cristina Escarmís; Encarnación Martínez-Salas; David Andreu; Ernest Giralt; Nuria Verdaguer; Ignacio Fita
Molecular evolution of aphthoviruses.
Virus genes 1995;11(2-3):197-207.
1994: Nuria Verdaguer; Mauricio G Mateu; J Bravo; J Tormo; Ernest Giralt; David Andreu; E Domingo; Ignacio Fita
Crystallization and preliminary X-ray diffraction studies of a monoclonal antibody Fab fragment against foot-and-mouth disease virus and of its complex with the main antigenic site peptide.
Proteins 1994;18(2):201-3.
1993: H Sfihi; Jean Liquier; L Urpi; Nuria Verdaguer; Juan A Subirana; J Igolen; Eliane Taillandier
A and Z canonical conformations in d(CnGCGn) crystals characterized by microFTIR and microRaman spectroscopies.
Biopolymers 1993;33(11):1715-23.
1993: L Tabernero; Nuria Verdaguer; Miquel Coll; Ignacio Fita; G A van der Marel; J H van Boom; A Rich; J Aymamí
Molecular structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor groove binding drug netropsin.
Biochemistry 1993;32(33):8403-10.
1993: Nuria Verdaguer; M Perelló; J Palau; Juan A Subirana
Helical structure of basic proteins from spermatozoa. Comparison with model peptides.
European journal of biochemistry / FEBS 1993;214(3):879-87.
1991: Nuria Verdaguer; J Aymami; D Fernández-Forner; Ignacio Fita; Miquel Coll; Tam Huynh-Dinh; J Igolen; Juan A Subirana
Molecular structure of a complete turn of A-DNA.
Journal of molecular biology 1991;221(2):623-35.
1990: Nuria Verdaguer; Ignacio Fita; Juan A Subirana
Molecular structure of L-lysyl-L-tyrosyl-L-serine acetate.
International journal of biological macromolecules 1990;12(5):315-20.
1989: L Urpi; J P Ridoux; Jean Liquier; Nuria Verdaguer; Ignacio Fita; Juan A Subirana; F Iglesias; Tam Huynh-Dinh; J Igolen; Eliane Taillandier
Conformations in crystals and solutions of d(CACGTG), d(CCGCGG) and d(GGCGCC) studied by vibrational spectroscopy.
Nucleic acids research 1989;17(16):6669-80.
1988: Nuria Verdaguer; L Urpí; Ignacio Fita; Juan A Subirana
Molecular structure of L-lysyl-L-alanyl-L-alanine: a tripeptide found in histone H1.
Biopolymers 1988;27(12):1887-96.