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Alan Verkman
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47
Ma, Tonghui
40
Yang, Baoxue
27
Song, Yuanlin
24
Matthay, Michael
21
Manley, Geoffrey
20
Galietta, Luis
20
Papadopoulos, Marios
18
Sonawane, Nitin
18
Brown, Dennis
15
Haggie, Peter
14
Thiagarajah, Jay
14
jayaraman, sujatha
13
Ausiello, Dennis
11
Skach, William
10
Verbavatz, Jean-Marc
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All Publications
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2009: Tradtrantip Lukmanee; Sonawane N D; Namkung Wan; Verkman A S
Nanomolar potency pyrimido-pyrrolo-quinoxalinedione CFTR inhibitor reduces cyst size in a polycystic kidney disease model.
Journal of medicinal chemistry 2009;52(20):6447-55.
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2009: Ruiz-Ederra Javier; Verkman A S
Aquaporin-1-facilitated keratocyte migration in cell culture and in vivo corneal wound healing models.
Experimental eye research 2009;89(2):159-65.
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2009: Saadoun S; Tait M J; Reza A; Davies D Ceri; Bell B A; Verkman A S; Papadopoulos M C
AQP4 gene deletion in mice does not alter blood-brain barrier integrity or brain morphology.
Neuroscience 2009;161(3):764-72.
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2009: Verkman A S
Aquaporins: translating bench research to human disease.
The Journal of experimental biology 2009;212(Pt 11):1707-15.
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2009: Namkung Wan; Song Yuanlin; Mills Aaron D; Padmawar Prashant; Finkbeiner Walter E; Verkman A S
In situ measurement of airway surface liquid [K+] using a ratioable K+-sensitive fluorescent dye.
The Journal of biological chemistry 2009;284(23):15916-26.
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2009: Haggie Peter M; Verkman A S
Defective organellar acidification as a cause of cystic fibrosis lung disease: reexamination of a recurring hypothesis.
American journal of physiology. Lung cellular and molecular physiology 2009;296(6):L859-67.
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2009: Ruiz-Ederra Javier; Levin Marc H; Verkman A S
In situ fluorescence measurement of tear film [Na+], [K+], [Cl-], and pH in mice shows marked hypertonicity in aquaporin-5 deficiency.
Investigative ophthalmology & visual science 2009;50(5):2132-8.
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2009: Magzoub Mazin; Zhang Hua; Dix James A; Verkman A S
Extracellular space volume measured by two-color pulsed dye infusion with microfiberoptic fluorescence photodetection.
Biophysical journal 2009;96(6):2382-90.
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2009: Crane Jonathan M; Verkman Alan S
Determinants of aquaporin-4 assembly in orthogonal arrays revealed by live-cell single-molecule fluorescence imaging.
Journal of cell science 2009;122(Pt 6):813-21.
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2009: Hara-Chikuma Mariko; Takahashi Kenzo; Chikuma Shunsuke; Verkman A S; Miyachi Yoshiki
The expression of differentiation markers in aquaporin-3 deficient epidermis.
Archives of dermatological research 2009;301(3):245-52.
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2009: Haggie Peter M; Verkman A S
Unimpaired lysosomal acidification in respiratory epithelial cells in cystic fibrosis.
The Journal of biological chemistry 2009;284(12):7681-6.
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2009: Verkman Alan S; Galietta Luis J V
Chloride channels as drug targets.
Nature reviews. Drug discovery 2009;8(2):153-71.
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2009: Yang Baoxue; Zhao Dan; Verkman A S
Hsp90 inhibitor partially corrects nephrogenic diabetes insipidus in a conditional knock-in mouse model of aquaporin-2 mutation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(2):503-12.
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2008: Zhang Hua; Verkman A S
Evidence against involvement of aquaporin-4 in cell-cell adhesion.
Journal of molecular biology 2008;382(5):1136-43.
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2008: Verkman A S
A cautionary note on cosmetics containing ingredients that increase aquaporin-3 expression.
Experimental dermatology 2008;17(10):871-2.
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2008: Sonawane N D; Verkman A S
Thiazolidinone CFTR inhibitors with improved water solubility identified by structure-activity analysis.
Bioorganic & medicinal chemistry 2008;16(17):8187-95.
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2008: Hara-Chikuma Mariko; Verkman A S
Roles of aquaporin-3 in the epidermis.
The Journal of investigative dermatology 2008;128(9):2145-51.
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2008: Lu Daniel C; Zhang Hua; Zador Zsolt; Verkman A S
Impaired olfaction in mice lacking aquaporin-4 water channels.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(9):3216-23.
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2008: Haggie Peter M; Verkman A S
Monomeric CFTR in plasma membranes in live cells revealed by single molecule fluorescence imaging.
The Journal of biological chemistry 2008;283(35):23510-3.
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2008: Yang Baoxue; Zhang Hua; Verkman A S
Lack of aquaporin-4 water transport inhibition by antiepileptics and arylsulfonamides.
Bioorganic & medicinal chemistry 2008;16(15):7489-93.
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2008: Crane Jonathan M; Van Hoek Alfred N; Skach William R; Verkman A S
Aquaporin-4 dynamics in orthogonal arrays in live cells visualized by quantum dot single particle tracking.
Molecular biology of the cell 2008;19(8):3369-78.
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2008: Jin Songwan; Zador Zsolt; Verkman A S
Random-walk model of diffusion in three dimensions in brain extracellular space: comparison with microfiberoptic photobleaching measurements.
Biophysical journal 2008;95(4):1785-94.
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2008: Sonawane N D; Zhao Dan; Zegarra-Moran Olga; Galietta Luis J V; Verkman A S
Nanomolar CFTR inhibition by pore-occluding divalent polyethylene glycol-malonic acid hydrazides.
Chemistry & biology 2008;15(7):718-28.
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2008: Verkman A S; Ruiz-Ederra Javier; Levin Marc H
Functions of aquaporins in the eye.
Progress in retinal and eye research 2008;27(4):420-33.
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2008: Yang Baoxue; Sonawane Nitin D; Zhao Dan; Somlo Stefan; Verkman A S
Small-molecule CFTR inhibitors slow cyst growth in polycystic kidney disease.
Journal of the American Society of Nephrology : JASN 2008;19(7):1300-10.
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2008: Caci Emanuela; Caputo Antonella; Hinzpeter Alexandre; Arous Nicole; Fanen Pascale; Sonawane Nitin; Verkman A S; Ravazzolo Roberto; Zegarra-Moran Olga; Galietta Luis J V
Evidence for direct CFTR inhibition by CFTR(inh)-172 based on Arg347 mutagenesis.
The Biochemical journal 2008;413(1):135-42.
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2008: Papadopoulos M C; Saadoun S; Verkman A S
Aquaporins and cell migration.
Pflügers Archiv : European journal of physiology 2008;456(4):693-700.
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2008: Namkung Wan; Padmawar Prashant; Mills Aaron D; Verkman A S
Cell-based fluorescence screen for K+ channels and transporters using an extracellular triazacryptand-based K+ sensor.
Journal of the American Chemical Society 2008;130(25):7794-5.
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2008: Verkman A S
Dissecting the roles of aquaporins in renal pathophysiology using transgenic mice.
Seminars in nephrology 2008;28(3):217-26.
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2008: Yang Baoxue; Zador Zsolt; Verkman A S
Glial cell aquaporin-4 overexpression in transgenic mice accelerates cytotoxic brain swelling.
The Journal of biological chemistry 2008;283(22):15280-6.
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2008: Verkman A S; Hara-Chikuma Mariko; Papadopoulos Marios C
Aquaporins--new players in cancer biology.
Journal of molecular medicine (Berlin, Germany) 2008;86(5):523-9.
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2008: Sonawane N D; Zegarra-Moran Olga; Namkung Wan; Galietta Luis J V; Verkman A S
Alpha-aminoazaheterocyclic-methylglyoxal adducts do not inhibit cystic fibrosis transmembrane conductance regulator chloride channel activity.
The Journal of pharmacology and experimental therapeutics 2008;325(2):529-35.
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2008: Yoo Choong Leol; Yu Gui Jun; Yang Baoxue; Robins Lori I; Verkman A S; Kurth Mark J
4'-Methyl-4,5'-bithiazole-based correctors of defective delta F508-CFTR cellular processing.
Bioorganic & medicinal chemistry letters 2008;18(8):2610-4.
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2008: Saadoun Samira; Bell B Anthony; Verkman A S; Papadopoulos Marios C
Greatly improved neurological outcome after spinal cord compression injury in AQP4-deficient mice.
Brain : a journal of neurology 2008;131(Pt 4):1087-98.
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2008: De La Fuente Ricardo; Namkung Wan; Mills Aaron; Verkman A S
Small-molecule screen identifies inhibitors of a human intestinal calcium-activated chloride channel.
Molecular pharmacology 2008;73(3):758-68.
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2008: Zador Zsolt; Magzoub Mazin; Jin Songwan; Manley Geoffrey T; Papadopoulos Marios C; Verkman A S
Microfiberoptic fluorescence photobleaching reveals size-dependent macromolecule diffusion in extracellular space deep in brain.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(3):870-9.
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2008: Hara-Chikuma Mariko; Verkman A S
Aquaporin-3 facilitates epidermal cell migration and proliferation during wound healing.
Journal of molecular medicine (Berlin, Germany) 2008;86(2):221-31.
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2008: Crane Jonathan M; Verkman A S
Long-range nonanomalous diffusion of quantum dot-labeled aquaporin-1 water channels in the cell plasma membrane.
Biophysical journal 2008;94(2):702-13.
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2008: Magzoub Mazin; Jin Songwan; Verkman A S
Enhanced macromolecule diffusion deep in tumors after enzymatic digestion of extracellular matrix collagen and its associated proteoglycan decorin.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(1):276-84.
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2008: Papadopoulos Marios C; Verkman A S
Potential utility of aquaporin modulators for therapy of brain disorders.
Progress in brain research 2008;170():589-601.
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2008: Dix James A; Verkman A S
Crowding effects on diffusion in solutions and cells.
Annual review of biophysics 2008;37():247-63.
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2008: Verkman A S
Mammalian aquaporins: diverse physiological roles and potential clinical significance.
Expert reviews in molecular medicine 2008;10():e13.
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2007: Thiagarajah Jay R; Zhao Dan; Verkman A S
Impaired enterocyte proliferation in aquaporin-3 deficiency in mouse models of colitis.
Gut 2007;56(11):1529-35.
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2007: Ruiz-Ederra Javier; Verkman A S
Aquaporin-1 independent microvessel proliferation in a neonatal mouse model of oxygen-induced retinopathy.
Investigative ophthalmology & visual science 2007;48(10):4802-10.
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2007: Haggie Peter M; Verkman A S
Cystic fibrosis transmembrane conductance regulator-independent phagosomal acidification in macrophages.
The Journal of biological chemistry 2007;282(43):31422-8.
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2007: Jin Songwan; Haggie Peter M; Verkman A S
Single-particle tracking of membrane protein diffusion in a potential: simulation, detection, and application to confined diffusion of CFTR Cl- channels.
Biophysical journal 2007;93(3):1079-88.
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2007: Ruiz-Ederra Javier; Zhang Hua; Verkman A S
Evidence against functional interaction between aquaporin-4 water channels and Kir4.1 potassium channels in retinal Müller cells.
The Journal of biological chemistry 2007;282(30):21866-72.
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2007: Yangthara Buranee; Mills Aaron; Chatsudthipong Varanuj; Tradtrantip Lukmanee; Verkman A S
Small-molecule vasopressin-2 receptor antagonist identified by a g-protein coupled receptor "pathway" screen.
Molecular pharmacology 2007;72(1):86-94.
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2007: Papadopoulos Marios C; Verkman Alan S
Aquaporin-4 and brain edema.
Pediatric nephrology (Berlin, Germany) 2007;22(6):778-84.
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2007: Sonawane N D; Zhao Dan; Zegarra-Moran Olga; Galietta Luis J V; Verkman A S
Lectin conjugates as potent, nonabsorbable CFTR inhibitors for reducing intestinal fluid secretion in cholera.
Gastroenterology 2007;132(4):1234-44.
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2007: Jin Songwan; Verkman A S
Single particle tracking of complex diffusion in membranes: simulation and detection of barrier, raft, and interaction phenomena.
The journal of physical chemistry. B 2007;111(14):3625-32.
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2007: Levin Marc H; de la Fuente Ricardo; Verkman A S
Urearetics: a small molecule screen yields nanomolar potency inhibitors of urea transporter UT-B.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(2):551-63.
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2007: Perez Aura; Issler Amanda C; Cotton Calvin U; Kelley Thomas J; Verkman Alan S; Davis Pamela B
CFTR inhibition mimics the cystic fibrosis inflammatory profile.
American journal of physiology. Lung cellular and molecular physiology 2007;292(2):L383-95.
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2007: Auguste Kurtis I; Jin Songwan; Uchida Kazunori; Yan Donghong; Manley Geoffrey T; Papadopoulos Marios C; Verkman A S
Greatly impaired migration of implanted aquaporin-4-deficient astroglial cells in mouse brain toward a site of injury.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(1):108-16.
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2006: Yang Baoxue; Kim Jung Kyung; Verkman A S
Comparative efficacy of HgCl2 with candidate aquaporin-1 inhibitors DMSO, gold, TEA+ and acetazolamide.
FEBS letters 2006;580(28-29):6679-84.
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2006: Haggie Peter M; Kim Jung Kyung; Lukacs Gergely L; Verkman A S
Tracking of quantum dot-labeled CFTR shows near immobilization by C-terminal PDZ interactions.
Molecular biology of the cell 2006;17(12):4937-45.
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2006: Bloch Orin; Auguste Kurtis I; Manley Geoffrey T; Verkman A S
Accelerated progression of kaolin-induced hydrocephalus in aquaporin-4-deficient mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(12):1527-37.
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2006: De La Fuente R; Sonawane N D; Arumainayagam D; Verkman A S
Small molecules with antimicrobial activity against E. coli and P. aeruginosa identified by high-throughput screening.
British journal of pharmacology 2006;149(5):551-9.
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2006: Magzoub Mazin; Padmawar Prashant; Dix James A; Verkman A S
Millisecond association kinetics of K+ with triazacryptand-based K+ indicators measured by fluorescence correlation spectroscopy.
The journal of physical chemistry. B 2006;110(42):21216-21.
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2006: Levin Marc H; Verkman A S
Aquaporin-3-dependent cell migration and proliferation during corneal re-epithelialization.
Investigative ophthalmology & visual science 2006;47(10):4365-72.
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2006: Ruiz-Ederra Javier; Verkman A S
Accelerated cataract formation and reduced lens epithelial water permeability in aquaporin-1-deficient mice.
Investigative ophthalmology & visual science 2006;47(9):3960-7.
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2006: Levin Marc H; Sullivan Shannon; Nielson Dennis; Yang Baoxue; Finkbeiner Walter E; Verkman A S
Hypertonic saline therapy in cystic fibrosis: Evidence against the proposed mechanism involving aquaporins.
The Journal of biological chemistry 2006;281(35):25803-12.
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2006: Hu Jie; Verkman A S
Increased migration and metastatic potential of tumor cells expressing aquaporin water channels.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(11):1892-4.
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2006: Verkman A S; Binder Devin K; Bloch Orin; Auguste Kurtis; Papadopoulos Marios C
Three distinct roles of aquaporin-4 in brain function revealed by knockout mice.
Biochimica et biophysica acta 2006;1758(8):1085-93.
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2006: Yang Baoxue; Zhao Dan; Qian Liman; Verkman A S
Mouse model of inducible nephrogenic diabetes insipidus produced by floxed aquaporin-2 gene deletion.
American journal of physiology. Renal physiology 2006;291(2):F465-72.
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2006: Yang Baoxue; Zhao Dan; Verkman A S
Evidence against functionally significant aquaporin expression in mitochondria.
The Journal of biological chemistry 2006;281(24):16202-6.
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2006: Verkman A S
Roles of aquaporins in kidney revealed by transgenic mice.
Seminars in nephrology 2006;26(3):200-8.
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2006: Ruiz-Ederra Javier; Verkman A S
Mouse model of sustained elevation in intraocular pressure produced by episcleral vein occlusion.
Experimental eye research 2006;82(5):879-84.
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2006: Thiagarajah Jay R; Kim Jung Kyung; Magzoub Mazin; Verkman A S
Slowed diffusion in tumors revealed by microfiberoptic epifluorescence photobleaching.
Nature methods 2006;3(4):275-80.
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2006: Verkman A S
Aquaporins in endothelia.
Kidney international 2006;69(7):1120-3.
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2006: Binder Devin K; Yao Xiaoming; Zador Zsolt; Sick Thomas J; Verkman Alan S; Manley Geoffrey T
Increased seizure duration and slowed potassium kinetics in mice lacking aquaporin-4 water channels.
Glia 2006;53(6):631-6.
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2006: Levin M H; Verkman A S
Aquaporins and CFTR in ocular epithelial fluid transport.
The Journal of membrane biology 2006;210(2):105-15.
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2006: Oshio Kotaro; Watanabe Hiroyuke; Yan Donghong; Verkman A S; Manley Geoffrey T
Impaired pain sensation in mice lacking Aquaporin-1 water channels.
Biochemical and biophysical research communications 2006;341(4):1022-8.
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2006: Song Yuanlin; Salinas Danieli; Nielson Dennis W; Verkman A S
Hyperacidity of secreted fluid from submucosal glands in early cystic fibrosis.
American journal of physiology. Cell physiology 2006;290(3):C741-9.
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2006: Dix James A; Hom Erik F Y; Verkman A S
Fluorescence correlation spectroscopy simulations of photophysical phenomena and molecular interactions: a molecular dynamics/monte carlo approach.
The journal of physical chemistry. B 2006;110(4):1896-906.
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2006: Suen Yat Fan; Robins Lori; Yang Baoxue; Verkman A S; Nantz Michael H; Kurth Mark J
Sulfamoyl-4-oxoquinoline-3-carboxamides: novel potentiators of defective DeltaF508-cystic fibrosis transmembrane conductance regulator chloride channel gating.
Bioorganic & medicinal chemistry letters 2006;16(3):537-40.
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2006: Fang Xiaohui; Song Yuanlin; Hirsch Jan; Galietta Luis J V; Pedemonte Nicoletta; Zemans Rachel L; Dolganov Gregory; Verkman A S; Matthay Michael A
Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells.
American journal of physiology. Lung cellular and molecular physiology 2006;290(2):L242-9.
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2006: Levin Marc H; Kim Jung Kyung; Hu Jie; Verkman A S
Potential difference measurements of ocular surface Na+ absorption analyzed using an electrokinetic model.
Investigative ophthalmology & visual science 2006;47(1):306-16.
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2006: Hara-Chikuma Mariko; Verkman A S
Aquaporin-1 facilitates epithelial cell migration in kidney proximal tubule.
Journal of the American Society of Nephrology : JASN 2006;17(1):39-45.
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2006: Sonawane N D; Hu Jie; Muanprasat Chatchai; Verkman A S
Luminally active, nonabsorbable CFTR inhibitors as potential therapy to reduce intestinal fluid loss in cholera.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(1):130-2.
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2006: Verkman A S; Lukacs Gergely L; Galietta Luis J V
CFTR chloride channel drug discovery--inhibitors as antidiarrheals and activators for therapy of cystic fibrosis.
Current pharmaceutical design 2006;12(18):2235-47.
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2006: Binder D K; Yao X; Verkman A S; Manley G T
Increased seizure duration in mice lacking aquaporin-4 water channels.
Acta neurochirurgica. Supplement 2006;96():389-92.
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2005: Saadoun Samira; Papadopoulos Marios C; Watanabe Hiroyuki; Yan Donghong; Manley Geoffrey T; Verkman A S
Involvement of aquaporin-4 in astroglial cell migration and glial scar formation.
Journal of cell science 2005;118(Pt 24):5691-8.
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2005: Sohara Eisei; Rai Tatemitsu; Miyazaki Jun-ichi; Verkman A S; Sasaki Sei; Uchida Shinichi
Defective water and glycerol transport in the proximal tubules of AQP7 knockout mice.
American journal of physiology. Renal physiology 2005;289(6):F1195-200.
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2005: Padmawar Prashant; Yao Xiaoming; Bloch Orin; Manley Geoffrey T; Verkman A S
K+ waves in brain cortex visualized using a long-wavelength K+-sensing fluorescent indicator.
Nature methods 2005;2(11):825-7.
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2005: Papadopoulos Marios C; Kim Jung Kyung; Verkman A S
Extracellular space diffusion in central nervous system: anisotropic diffusion measured by elliptical surface photobleaching.
Biophysical journal 2005;89(5):3660-8.
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2005: Bloch Orin; Papadopoulos Marios C; Manley Geoffrey T; Verkman A S
Aquaporin-4 gene deletion in mice increases focal edema associated with staphylococcal brain abscess.
Journal of neurochemistry 2005;95(1):254-62.
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2005: Pedemonte Nicoletta; Lukacs Gergely L; Du Kai; Caci Emanuela; Zegarra-Moran Olga; Galietta Luis J V; Verkman A S
Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening.
The Journal of clinical investigation 2005;115(9):2564-71.
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2005: Verkman A S
More than just water channels: unexpected cellular roles of aquaporins.
Journal of cell science 2005;118(Pt 15):3225-32.
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2005: Hara-Chikuma Mariko; Verkman A S
Aquaporin-3 functions as a glycerol transporter in mammalian skin.
Biology of the cell / under the auspices of the European Cell Biology Organization 2005;97(7):479-86.
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2005: Pedemonte Nicoletta; Sonawane N D; Taddei Alessandro; Hu Jie; Zegarra-Moran Olga; Suen Yat Fan; Robins Lori I; Dicus Christopher W; Willenbring Dan; Nantz Michael H; Kurth Mark J; Galietta Luis J V; Verkman A S
Phenylglycine and sulfonamide correctors of defective delta F508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating.
Molecular pharmacology 2005;67(5):1797-807.
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2005: Schulz Benjamin L; Sloane Andrew J; Robinson Leanne J; Sebastian Lucille T; Glanville Allan R; Song Yuanlin; Verkman Alan S; Harry Jenny L; Packer Nicolle H; Karlsson Niclas G
Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.
The Biochemical journal 2005;387(Pt 3):911-9.
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2005: Saadoun Samira; Papadopoulos Marios C; Hara-Chikuma Mariko; Verkman A S
Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption.
Nature 2005;434(7034):786-92.
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2005: Thiagarajah Jay R; Verkman A S
New drug targets for cholera therapy.
Trends in pharmacological sciences 2005;26(4):172-5.
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2005: Levin Marc H; Verkman A S
CFTR-regulated chloride transport at the ocular surface in living mice measured by potential differences.
Investigative ophthalmology & visual science 2005;46(4):1428-34.
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2005: Thiagarajah Jay R; Papadopoulos Marios C; Verkman A S
Noninvasive early detection of brain edema in mice by near-infrared light scattering.
Journal of neuroscience research 2005;80(2):293-9.
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2005: Hara-Chikuma Mariko; Wang Yinghong; Guggino Sandra E; Guggino William B; Verkman A S
Impaired acidification in early endosomes of ClC-5 deficient proximal tubule.
Biochemical and biophysical research communications 2005;329(3):941-6.
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2005: Hara-Chikuma Mariko; Sohara Eisei; Rai Tatemitsu; Ikawa Masahito; Okabe Masaru; Sasaki Sei; Uchida Shinichi; Verkman A S
Progressive adipocyte hypertrophy in aquaporin-7-deficient mice: adipocyte glycerol permeability as a novel regulator of fat accumulation.
The Journal of biological chemistry 2005;280(16):15493-6.
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2005: Papadopoulos Marios C; Verkman A S
Aquaporin-4 gene disruption in mice reduces brain swelling and mortality in pneumococcal meningitis.
The Journal of biological chemistry 2005;280(14):13906-12.
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2005: Dauty Emmanuel; Verkman A S
Actin cytoskeleton as the principal determinant of size-dependent DNA mobility in cytoplasm: a new barrier for non-viral gene delivery.
The Journal of biological chemistry 2005;280(9):7823-8.
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2005: Salinas Danieli; Haggie Peter M; Thiagarajah Jay R; Song Yuanlin; Rosbe Kristina; Finkbeiner Walter E; Nielson Dennis W; Verkman A S
Submucosal gland dysfunction as a primary defect in cystic fibrosis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(3):431-3.
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2005: Papadopoulos Marios C; Binder Devin K; Verkman A S
Enhanced macromolecular diffusion in brain extracellular space in mouse models of vasogenic edema measured by cortical surface photobleaching.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(3):425-7.
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2005: Sonawane N D; Muanprasat Chatchai; Nagatani Ray; Song Yuanlin; Verkman A S
In vivo pharmacology and antidiarrheal efficacy of a thiazolidinone CFTR inhibitor in rodents.
Journal of pharmaceutical sciences 2005;94(1):134-43.
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2005: Oshio Kotaro; Watanabe Hiroyuki; Song Yaunlin; Verkman A S; Manley Geoffrey T
Reduced cerebrospinal fluid production and intracranial pressure in mice lacking choroid plexus water channel Aquaporin-1.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(1):76-8.
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2005: Hara-Chikuma Mariko; Yang Baoxue; Sonawane N D; Sasaki Sei; Uchida Shinichi; Verkman A S
ClC-3 chloride channels facilitate endosomal acidification and chloride accumulation.
The Journal of biological chemistry 2005;280(2):1241-7.
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2004: Da Tong; Verkman A S
Aquaporin-4 gene disruption in mice protects against impaired retinal function and cell death after ischemia.
Investigative ophthalmology & visual science 2004;45(12):4477-83.
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2004: Levin Marc H; Verkman A S
Aquaporin-dependent water permeation at the mouse ocular surface: in vivo microfluorimetric measurements in cornea and conjunctiva.
Investigative ophthalmology & visual science 2004;45(12):4423-32.
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2004: Salinas Danieli B; Pedemonte Nicoletta; Muanprasat Chatchai; Finkbeiner Walter F; Nielson Dennis W; Verkman A S
CFTR involvement in nasal potential differences in mice and pigs studied using a thiazolidinone CFTR inhibitor.
American journal of physiology. Lung cellular and molecular physiology 2004;287(5):L936-43.
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2004: Binder Devin K; Papadopoulos Marios C; Haggie Peter M; Verkman A S
In vivo measurement of brain extracellular space diffusion by cortical surface photobleaching.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(37):8049-56.
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2004: Dauty Emmanuel; Verkman A S
Molecular crowding reduces to a similar extent the diffusion of small solutes and macromolecules: measurement by fluorescence correlation spectroscopy.
Journal of molecular recognition : JMR 2004;17(5):441-7.
-
2004: Verkman Alan S
Drug discovery and epithelial physiology.
Current opinion in nephrology and hypertension 2004;13(5):563-8.
-
2004: Song Yuanlin; Sonawane N D; Salinas Danieli; Qian Liman; Pedemonte Nicoletta; Galietta Luis J V; Verkman A S
Evidence against the rescue of defective DeltaF508-CFTR cellular processing by curcumin in cell culture and mouse models.
The Journal of biological chemistry 2004;279(39):40629-33.
-
2004: Muanprasat Chatchai; Sonawane N D; Salinas Danieli; Taddei Alessandro; Galietta Luis J V; Verkman A S
Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure-activity analysis, and in vivo efficacy.
The Journal of general physiology 2004;124(2):125-37.
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2004: Papadopoulos Marios C; Manley Geoffrey T; Krishna Sanjeev; Verkman A S
Aquaporin-4 facilitates reabsorption of excess fluid in vasogenic brain edema.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(11):1291-3.
-
2004: Thiagarajah Jay R; Song Yuanlin; Haggie Peter M; Verkman A S
A small molecule CFTR inhibitor produces cystic fibrosis-like submucosal gland fluid secretions in normal airways.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(7):875-7.
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2004: Verkman A S
Drug discovery in academia.
American journal of physiology. Cell physiology 2004;286(3):C465-74.
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2004: Binder Devin K; Oshio Kotaro; Ma Tonghui; Verkman A S; Manley Geoffrey T
Increased seizure threshold in mice lacking aquaporin-4 water channels.
Neuroreport 2004;15(2):259-62.
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2004: Thiagarajah Jay R; Broadbent Talmage; Hsieh Emily; Verkman Alan S
Prevention of toxin-induced intestinal ion and fluid secretion by a small-molecule CFTR inhibitor.
Gastroenterology 2004;126(2):511-9.
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2004: Haggie Peter M; Stanton Bruce A; Verkman A S
Increased diffusional mobility of CFTR at the plasma membrane after deletion of its C-terminal PDZ binding motif.
The Journal of biological chemistry 2004;279(7):5494-500.
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2004: Solenov Eugen; Watanabe Hiroyuki; Manley Geoffrey T; Verkman A S
Sevenfold-reduced osmotic water permeability in primary astrocyte cultures from AQP-4-deficient mice, measured by a fluorescence quenching method.
American journal of physiology. Cell physiology 2004;286(2):C426-32.
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2004: Taddei Alessandro; Folli Chiara; Zegarra-Moran Olga; Fanen Pascale; Verkman A S; Galietta Luis J V
Altered channel gating mechanism for CFTR inhibition by a high-affinity thiazolidinone blocker.
FEBS letters 2004;558(1-3):52-6.
-
2004: Papadopoulos M C; Saadoun S; Binder D K; Manley G T; Krishna S; Verkman A S
Molecular mechanisms of brain tumor edema.
Neuroscience 2004;129(4):1011-20.
-
2004: Oshio K; Binder D K; Yang B; Schecter S; Verkman A S; Manley G T
Expression of aquaporin water channels in mouse spinal cord.
Neuroscience 2004;127(3):685-93.
-
2003: Thiagarajah Jay R; Verkman A S
CFTR pharmacology and its role in intestinal fluid secretion.
Current opinion in pharmacology 2003;3(6):594-9.
-
2003: Song Yuanlin; Thiagarajah Jay; Verkman A S
Sodium and chloride concentrations, pH, and depth of airway surface liquid in distal airways.
The Journal of general physiology 2003;122(5):511-9.
-
2003: Sonawane N D; Szoka Francis C; Verkman A S
Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes.
The Journal of biological chemistry 2003;278(45):44826-31.
-
2003: Springsteel Mark F; Galietta Luis J V; Ma Tonghui; By Kolbot; Berger Gideon O; Yang Hong; Dicus Christopher W; Choung Wonken; Quan Chao; Shelat Anang A; Guy R Kiplin; Verkman A S; Kurth Mark J; Nantz Michael H
Benzoflavone activators of the cystic fibrosis transmembrane conductance regulator: towards a pharmacophore model for the nucleotide-binding domain.
Bioorganic & medicinal chemistry 2003;11(18):4113-20.
-
2003: Yang Hong; Shelat Anang A; Guy R Kiplin; Gopinath Vadiraj S; Ma Tonghui; Du Kai; Lukacs Gergely L; Taddei Alessandro; Folli Chiara; Pedemonte Nicoletta; Galietta Luis J V; Verkman A S
Nanomolar affinity small molecule correctors of defective Delta F508-CFTR chloride channel gating.
The Journal of biological chemistry 2003;278(37):35079-85.
-
2003: Sammelson Robert E; Ma T; Galietta Luis J V; Verkman A S; Kurth Mark J
3-(2-Benzyloxyphenyl)isoxazoles and isoxazolines: synthesis and evaluation as CFTR activators.
Bioorganic & medicinal chemistry letters 2003;13(15):2509-12.
-
2003: Caci Emanuela; Folli Chiara; Zegarra-Moran Olga; Ma Tonghui; Springsteel Mark F; Sammelson Robert E; Nantz Michael H; Kurth Mark J; Verkman A S; Galietta Luis J V
CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds.
American journal of physiology. Lung cellular and molecular physiology 2003;285(1):L180-8.
-
2003: Hara Mariko; Verkman A S
Glycerol replacement corrects defective skin hydration, elasticity, and barrier function in aquaporin-3-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(12):7360-5.
-
2003: Sonawane N D; Verkman A S
Determinants of [Cl-] in recycling and late endosomes and Golgi complex measured using fluorescent ligands.
The Journal of cell biology 2003;160(7):1129-38.
-
2003: Verkman A S
Role of aquaporin water channels in eye function.
Experimental eye research 2003;76(2):137-43.
-
2003: Verkman A S; Song Yuanlin; Thiagarajah Jay R
Role of airway surface liquid and submucosal glands in cystic fibrosis lung disease.
American journal of physiology. Cell physiology 2003;284(1):C2-15.
-
2003: Jiang Jinjun; Song Yuanlin; Bai Chunxue; Koller Beverly H; Matthay Michael A; Verkman A S
Pleural surface fluorescence measurement of Na+ and Cl- transport across the air space-capillary barrier.
Journal of applied physiology (Bethesda, Md. : 1985) 2003;94(1):343-52.
-
2003: Oshio K; Song Y; Verkman A S; Manley G T
Aquaporin-1 deletion reduces osmotic water permeability and cerebrospinal fluid production.
Acta neurochirurgica. Supplement 2003;86():525-8.
-
2003: Oshio K; Binder D K; Bollen A; Verkman A S; Berger M S; Manley G T
Aquaporin-1 expression in human glial tumors suggests a potential novel therapeutic target for tumor-associated edema.
Acta neurochirurgica. Supplement 2003;86():499-502.
-
2003: Verkman Alan S
Diffusion in cells measured by fluorescence recovery after photobleaching.
Methods in enzymology 2003;360():635-48.
-
2002: Ma Tonghui; Thiagarajah Jay R; Yang Hong; Sonawane Nitin D; Folli Chiara; Galietta Luis J V; Verkman A S
Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion.
The Journal of clinical investigation 2002;110(11):1651-8.
-
2002: Hara Mariko; Ma Tonghui; Verkman A S
Selectively reduced glycerol in skin of aquaporin-3-deficient mice may account for impaired skin hydration, elasticity, and barrier recovery.
The Journal of biological chemistry 2002;277(48):46616-21.
-
2002: Mann Stephanie E; Ricke Emily A; Yang Baxoue A; Verkman Alan S; Taylor Robert N
Expression and localization of aquaporin 1 and 3 in human fetal membranes.
American journal of obstetrics and gynecology 2002;187(4):902-7.
-
2002: Haggie Peter M; Verkman A S
Diffusion of tricarboxylic acid cycle enzymes in the mitochondrial matrix in vivo. Evidence for restricted mobility of a multienzyme complex.
The Journal of biological chemistry 2002;277(43):40782-8.
-
2002: Ma Tonghui; Vetrivel L; Yang Hong; Pedemonte Nicoletta; Zegarra-Moran Olga; Galietta Luis J V; Verkman A S
High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening.
The Journal of biological chemistry 2002;277(40):37235-41.
-
2002: Papadopoulos Marios C; Krishna Sanjeev; Verkman A S
Aquaporin water channels and brain edema.
The Mount Sinai journal of medicine, New York 2002;69(4):242-8.
-
2002: Mennone Albert; Verkman Alan S; Boyer James L
Unimpaired osmotic water permeability and fluid secretion in bile duct epithelia of AQP1 null mice.
American journal of physiology. Gastrointestinal and liver physiology 2002;283(3):G739-46.
-
2002: Yang Baoxue; Verkman A S
Analysis of double knockout mice lacking aquaporin-1 and urea transporter UT-B. Evidence for UT-B-facilitated water transport in erythrocytes.
The Journal of biological chemistry 2002;277(39):36782-6.
-
2002: Fang Xiaohui; Yang Baoxue; Matthay Michael A; Verkman A S
Evidence against aquaporin-1-dependent CO2 permeability in lung and kidney.
The Journal of physiology 2002;542(Pt 1):63-9.
-
2002: Verkman A S
Does aquaporin-1 pass gas? An opposing view.
The Journal of physiology 2002;542(Pt 1):31.
-
2002: Hom Erik F Y; Verkman A S
Analysis of coupled bimolecular reaction kinetics and diffusion by two-color fluorescence correlation spectroscopy: enhanced resolution of kinetics by resonance energy transfer.
Biophysical journal 2002;83(1):533-46.
-
2002: Verkman A S
Aquaporin water channels and endothelial cell function.
Journal of anatomy 2002;200(6):617-27.
-
2002: Song Yuanlin; Sonawane Nitin; Verkman A S
Localization of aquaporin-5 in sweat glands and functional analysis using knockout mice.
The Journal of physiology 2002;541(Pt 2):561-8.
-
2002: Zhang Duo; Vetrivel L; Verkman A S
Aquaporin deletion in mice reduces intraocular pressure and aqueous fluid production.
The Journal of general physiology 2002;119(6):561-9.
-
2002: Thiagarajah Jay R; Verkman A S
Aquaporin deletion in mice reduces corneal water permeability and delays restoration of transparency after swelling.
The Journal of biological chemistry 2002;277(21):19139-44.
-
2002: Ma Tonghui; Hara Mariko; Sougrat Rachid; Verbavatz Jean-Marc; Verkman A S
Impaired stratum corneum hydration in mice lacking epidermal water channel aquaporin-3.
The Journal of biological chemistry 2002;277(19):17147-53.
-
2002: Haggie Peter M; Stanton Bruce A; Verkman A S
Diffusional mobility of the cystic fibrosis transmembrane conductance regulator mutant, delta F508-CFTR, in the endoplasmic reticulum measured by photobleaching of GFP-CFTR chimeras.
The Journal of biological chemistry 2002;277(19):16419-25.
-
2002: Yang Baoxue; Bankir Lise; Gillespie Annemarie; Epstein Charles J; Verkman A S
Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B.
The Journal of biological chemistry 2002;277(12):10633-7.
-
2002: Li Jiang; Patil Rajkumar V; Verkman A S
Mildly abnormal retinal function in transgenic mice without Müller cell aquaporin-4 water channels.
Investigative ophthalmology & visual science 2002;43(2):573-9.
-
2002: Fang X; Fukuda N; Barbry P; Sartori C; Verkman A S; Matthay M A
Novel role for CFTR in fluid absorption from the distal airspaces of the lung.
The Journal of general physiology 2002;119(2):199-207.
-
2002: Sonawane N D; Thiagarajah Jay R; Verkman A S
Chloride concentration in endosomes measured using a ratioable fluorescent Cl- indicator: evidence for chloride accumulation during acidification.
The Journal of biological chemistry 2002;277(7):5506-13.
-
2002: Verkman Alan S; Yang Baoxue
Aquaporin gene delivery to kidney.
Kidney international 2002;61(1 Suppl):S120-4.
-
2002: Verkman Alan S
Solute and macromolecule diffusion in cellular aqueous compartments.
Trends in biochemical sciences 2002;27(1):27-33.
-
2002: Solenov E I; Vetrivel L; Oshio Kotaro; Manley Geoffrey T; Verkman A S
Optical measurement of swelling and water transport in spinal cord slices from aquaporin null mice.
Journal of neuroscience methods 2002;113(1):85-90.
-
2002: Verkman Alan S
Physiological importance of aquaporin water channels.
Annals of medicine 2002;34(3):192-200.
-
2002: Verkman A S
Renal concentrating and diluting function in deficiency of specific aquaporin genes.
Experimental nephrology 2002;10(4):235-40.
-
2002: Verkman Alan S; Jayaraman Sujatha
Fluorescent indicator methods to assay functional CFTR expression in cells.
Methods in molecular medicine 2002;70():187-96.
-
2001: Thiagarajah J R; Jayaraman S; Naftalin R J; Verkman A S
In vivo fluorescence measurement of Na(+) concentration in the pericryptal space of mouse descending colon.
American journal of physiology. Cell physiology 2001;281(6):C1898-903.
-
2001: Galietta L V; Jayaraman S; Verkman A S
Cell-based assay for high-throughput quantitative screening of CFTR chloride transport agonists.
American journal of physiology. Cell physiology 2001;281(5):C1734-42.
-
2001: Jayaraman S; Song Y; Verkman A S
Airway surface liquid pH in well-differentiated airway epithelial cell cultures and mouse trachea.
American journal of physiology. Cell physiology 2001;281(5):C1504-11.
-
2001: Song Y; Verkman A S
Aquaporin-5 dependent fluid secretion in airway submucosal glands.
The Journal of biological chemistry 2001;276(44):41288-92.
-
2001: Li J; Verkman A S
Impaired hearing in mice lacking aquaporin-4 water channels.
The Journal of biological chemistry 2001;276(33):31233-7.
-
2001: Joo N S; Krouse M E; Wu J V; Saenz Y; Jayaraman S; Verkman A S; Wine J J
HCO3- transport in relation to mucus secretion from submucosal glands.
JOP : Journal of the pancreas 2001;2(4 Suppl):280-4.
-
2001: Jayaraman S; Joo N S; Reitz B; Wine J J; Verkman A S
Submucosal gland secretions in airways from cystic fibrosis patients have normal [Na(+)] and pH but elevated viscosity.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(14):8119-23.
-
2001: Galietta L J; Haggie P M; Verkman A S
Green fluorescent protein-based halide indicators with improved chloride and iodide affinities.
FEBS letters 2001;499(3):220-4.
-
2001: Song Y; Jayaraman S; Yang B; Matthay M A; Verkman A S
Role of aquaporin water channels in airway fluid transport, humidification, and surface liquid hydration.
The Journal of general physiology 2001;117(6):573-82.
-
2001: Levin M H; Haggie P M; Vetrivel L; Verkman A S
Diffusion in the endoplasmic reticulum of an aquaporin-2 mutant causing human nephrogenic diabetes insipidus.
The Journal of biological chemistry 2001;276(24):21331-6.
-
2001: Galietta L J; Springsteel M F; Eda M; Niedzinski E J; By K; Haddadin M J; Kurth M J; Nantz M H; Verkman A S
Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds.
The Journal of biological chemistry 2001;276(23):19723-8.
-
2001: Jayaraman S; Song Y; Verkman A S
Airway surface liquid osmolality measured using fluorophore-encapsulated liposomes.
The Journal of general physiology 2001;117(5):423-30.
-
2001: Jayaraman S; Song Y; Vetrivel L; Shankar L; Verkman A S
Noninvasive in vivo fluorescence measurement of airway-surface liquid depth, salt concentration, and pH.
The Journal of clinical investigation 2001;107(3):317-24.
-
2001: Ma T; Jayaraman S; Wang K S; Song Y; Yang B; Li J; Bastidas J A; Verkman A S
Defective dietary fat processing in transgenic mice lacking aquaporin-1 water channels.
American journal of physiology. Cell physiology 2001;280(1):C126-34.
-
2001: Yang B; Ma T; Verkman A S
Erythrocyte water permeability and renal function in double knockout mice lacking aquaporin-1 and aquaporin-3.
The Journal of biological chemistry 2001;276(1):624-8.
-
2001: Yang B; Gillespie A; Carlson E J; Epstein C J; Verkman A S
Neonatal mortality in an aquaporin-2 knock-in mouse model of recessive nephrogenic diabetes insipidus.
The Journal of biological chemistry 2001;276(4):2775-9.
-
2000: Song Y; Yang B; Matthay M A; Ma T; Verkman A S
Role of aquaporin water channels in pleural fluid dynamics.
American journal of physiology. Cell physiology 2000;279(6):C1744-50.
-
2000: Verkman A S
Physiological importance of aquaporins: lessons from knockout mice.
Current opinion in nephrology and hypertension 2000;9(5):517-22.
-
2000: Wang K S; Ma T; Filiz F; Verkman A S; Bastidas J A
Colon water transport in transgenic mice lacking aquaporin-4 water channels.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(2):G463-70.
-
2000: Wang K S; Komar A R; Ma T; Filiz F; McLeroy J; Hoda K; Verkman A S; Bastidas J A
Gastric acid secretion in aquaporin-4 knockout mice.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(2):G448-53.
-
2000: Rao S; Verkman A S
Analysis of organ physiology in transgenic mice.
American journal of physiology. Cell physiology 2000;279(1):C1-C18.
-
2000: Song Y; Fukuda N; Bai C; Ma T; Matthay M A; Verkman A S
Role of aquaporins in alveolar fluid clearance in neonatal and adult lung, and in oedema formation following acute lung injury: studies in transgenic aquaporin null mice.
The Journal of physiology 2000;525 Pt 3():771-9.
-
2000: Yang B; Verbavatz J M; Song Y; Vetrivel L; Manley G; Kao W M; Ma T; Verkman A S
Skeletal muscle function and water permeability in aquaporin-4 deficient mice.
American journal of physiology. Cell physiology 2000;278(6):C1108-15.
-
2000: Jayaraman S; Verkman A S
Quenching mechanism of quinolinium-type chloride-sensitive fluorescent indicators.
Biophysical chemistry 2000;85(1):49-57.
-
2000: Moore M; Ma T; Yang B; Verkman A S
Tear secretion by lacrimal glands in transgenic mice lacking water channels AQP1, AQP3, AQP4 and AQP5.
Experimental eye research 2000;70(5):557-62.
-
2000: Verkman A S; Matthay M A; Song Y
Aquaporin water channels and lung physiology.
American journal of physiology. Lung cellular and molecular physiology 2000;278(5):L867-79.
-
2000: Ma T; Song Y; Yang B; Gillespie A; Carlson E J; Epstein C J; Verkman A S
Nephrogenic diabetes insipidus in mice lacking aquaporin-3 water channels.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(8):4386-91.
-
2000: Verkman A S; Yang B; Song Y; Manley G T; Ma T
Role of water channels in fluid transport studied by phenotype analysis of aquaporin knockout mice.
Experimental physiology 2000;85 Spec No():233S-241S.
-
2000: Yang B; Ma T; Dong J Y; Verkman A S
Partial correction of the urinary concentrating defect in aquaporin-1 null mice by adenovirus-mediated gene delivery.
Human gene therapy 2000;11(4):567-75.
-
2000: Jayaraman S; Haggie P; Wachter R M; Remington S J; Verkman A S
Mechanism and cellular applications of a green fluorescent protein-based halide sensor.
The Journal of biological chemistry 2000;275(9):6047-50.
-
2000: Manley G T; Fujimura M; Ma T; Noshita N; Filiz F; Bollen A W; Chan P; Verkman A S
Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke.
Nature medicine 2000;6(2):159-63.
-
2000: Umenishi F; Verbavatz J M; Verkman A S
cAMP regulated membrane diffusion of a green fluorescent protein-aquaporin 2 chimera.
Biophysical journal 2000;78(2):1024-35.
-
2000: Yang B; Fukuda N; van Hoek A; Matthay M A; Ma T; Verkman A S
Carbon dioxide permeability of aquaporin-1 measured in erythrocytes and lung of aquaporin-1 null mice and in reconstituted proteoliposomes.
The Journal of biological chemistry 2000;275(4):2686-92.
-
2000: Verkman A S; Mitra A K
Structure and function of aquaporin water channels.
American journal of physiology. Renal physiology 2000;278(1):F13-28.
-
2000: Lukacs G L; Haggie P; Seksek O; Lechardeur D; Freedman N; Verkman A S
Size-dependent DNA mobility in cytoplasm and nucleus.
The Journal of biological chemistry 2000;275(3):1625-9.
-
2000: Verkman A S
Water permeability measurement in living cells and complex tissues.
The Journal of membrane biology 2000;173(2):73-87.
-
2000: Ma T; Fukuda N; Song Y; Matthay M A; Verkman A S
Lung fluid transport in aquaporin-5 knockout mice.
The Journal of clinical investigation 2000;105(1):93-100.
-
2000: Song Y; Ma T; Matthay M A; Verkman A S
Role of aquaporin-4 in airspace-to-capillary water permeability in intact mouse lung measured by a novel gravimetric method.
The Journal of general physiology 2000;115(1):17-27.
-
1999: Tamarappoo B K; Yang B; Verkman A S
Misfolding of mutant aquaporin-2 water channels in nephrogenic diabetes insipidus.
The Journal of biological chemistry 1999;274(49):34825-31.
-
1999: Jayaraman S; Teitler L; Skalski B; Verkman A S
Long-wavelength iodide-sensitive fluorescent indicators for measurement of functional CFTR expression in cells.
The American journal of physiology 1999;277(5 Pt 1):C1008-18.
-
1999: Ma T; Song Y; Gillespie A; Carlson E J; Epstein C J; Verkman A S
Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels.
The Journal of biological chemistry 1999;274(29):20071-4.
-
1999: Ma T; Verkman A S
Aquaporin water channels in gastrointestinal physiology.
The Journal of physiology 1999;517 ( Pt 2)():317-26.
-
1999: Dayel M J; Hom E F; Verkman A S
Diffusion of green fluorescent protein in the aqueous-phase lumen of endoplasmic reticulum.
Biophysical journal 1999;76(5):2843-51.
-
1999: Verkman A S
Lessons on renal physiology from transgenic mice lacking aquaporin water channels.
Journal of the American Society of Nephrology : JASN 1999;10(5):1126-35.
-
1999: Farinas J; Verkman A S
Receptor-mediated targeting of fluorescent probes in living cells.
The Journal of biological chemistry 1999;274(12):7603-6.
-
1999: Jayaraman S; Biwersi J; Verkman A S
Synthesis and characterization of dual-wavelength Cl--sensitive fluorescent indicators for ratio imaging.
The American journal of physiology 1999;276(3 Pt 1):C747-57.
-
1999: Bai C; Fukuda N; Song Y; Ma T; Matthay M A; Verkman A S
Lung fluid transport in aquaporin-1 and aquaporin-4 knockout mice.
The Journal of clinical investigation 1999;103(4):555-61.
-
1999: Yang B; Folkesson H G; Yang J; Matthay M A; Ma T; Verkman A S
Reduced osmotic water permeability of the peritoneal barrier in aquaporin-1 knockout mice.
The American journal of physiology 1999;276(1 Pt 1):C76-81.
-
1999: Verkman A S
Green fluorescent protein as a probe to study intracellular solute diffusion.
Methods in enzymology 1999;302():250-64.
-
1998: Verkman A S
Role of aquaporin water channels in kidney and lung.
The American journal of the medical sciences 1998;316(5):310-20.
-
1998: Bai C; Biwersi J; Verkman A S; Matthay M A
A mouse model to test the in vivo efficacy of chemical chaperones.
Journal of pharmacological and toxicological methods 1998;40(1):39-45.
-
1998: Ma T; Yang B; Matthay M A; Verkman A S
Evidence against a role of mouse, rat, and two cloned human t1alpha isoforms as a water channel or a regulator of aquaporin-type water channels.
American journal of respiratory cell and molecular biology 1998;19(1):143-9.
-
1998: Periasamy N; Verkman A S
Analysis of fluorophore diffusion by continuous distributions of diffusion coefficients: application to photobleaching measurements of multicomponent and anomalous diffusion.
Biophysical journal 1998;75(1):557-67.
-
1998: Umenishi F; Verkman A S
Isolation and functional analysis of alternative promoters in the human aquaporin-4 water channel gene.
Genomics 1998;50(3):373-7.
-
1998: Tamarappoo B K; Verkman A S
Defective aquaporin-2 trafficking in nephrogenic diabetes insipidus and correction by chemical chaperones.
The Journal of clinical investigation 1998;101(10):2257-67.
-
1998: Olveczky B P; Verkman A S
Monte Carlo analysis of obstructed diffusion in three dimensions: application to molecular diffusion in organelles.
Biophysical journal 1998;74(5):2722-30.
-
1998: Yang B; Verkman A S
Urea transporter UT3 functions as an efficient water channel. Direct evidence for a common water/urea pathway.
The Journal of biological chemistry 1998;273(16):9369-72.
-
1998: Carter E P; Olveczky B P; Matthay M A; Verkman A S
High microvascular endothelial water permeability in mouse lung measured by a pleural surface fluorescence method.
Biophysical journal 1998;74(4):2121-8.
-
1998: Kneen M; Farinas J; Li Y; Verkman A S
Green fluorescent protein as a noninvasive intracellular pH indicator.
Biophysical journal 1998;74(3):1591-9.
-
1998: Dobbs L G; Gonzalez R; Matthay M A; Carter E P; Allen L; Verkman A S
Highly water-permeable type I alveolar epithelial cells confer high water permeability between the airspace and vasculature in rat lung.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):2991-6.
-
1998: Neville D C; Rozanas C R; Tulk B M; Townsend R R; Verkman A S
Expression and characterization of the NBD1-R domain region of CFTR: evidence for subunit-subunit interactions.
Biochemistry 1998;37(8):2401-9.
-
1998: Umenishi F; Verkman A S
Isolation of the human aquaporin-1 promoter and functional characterization in human erythroleukemia cell lines.
Genomics 1998;47(3):341-9.
-
1998: Partikian A; Olveczky B; Swaminathan R; Li Y; Verkman A S
Rapid diffusion of green fluorescent protein in the mitochondrial matrix.
The Journal of cell biology 1998;140(4):821-9.
-
1998: Ma T; Yang B; Gillespie A; Carlson E J; Epstein C J; Verkman A S
Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels.
The Journal of biological chemistry 1998;273(8):4296-9.
-
1997: Ma T; Yang B; Verkman A S
Cloning of a novel water and urea-permeable aquaporin from mouse expressed strongly in colon, placenta, liver, and heart.
Biochemical and biophysical research communications 1997;240(2):324-8.
-
1997: Olveczky B P; Periasamy N; Verkman A S
Mapping fluorophore distributions in three dimensions by quantitative multiple angle-total internal reflection fluorescence microscopy.
Biophysical journal 1997;73(5):2836-47.
-
1997: Farinas J; Kneen M; Moore M; Verkman A S
Plasma membrane water permeability of cultured cells and epithelia measured by light microscopy with spatial filtering.
The Journal of general physiology 1997;110(3):283-96.
-
1997: Carter E P; Umenishi F; Matthay M A; Verkman A S
Developmental changes in water permeability across the alveolar barrier in perinatal rabbit lung.
The Journal of clinical investigation 1997;100(5):1071-8.
-
1997: Ma T; Yang B; Gillespie A; Carlson E J; Epstein C J; Verkman A S
Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4.
The Journal of clinical investigation 1997;100(5):957-62.
-
1997: Ma T; Yang B; Umenishi F; Verkman A S
Closely spaced tandem arrangement of AQP2, AQP5, and AQP6 genes in a 27-kilobase segment at chromosome locus 12q13.
Genomics 1997;43(3):387-9.
-
1997: Seksek O; Biwersi J; Verkman A S
Translational diffusion of macromolecule-sized solutes in cytoplasm and nucleus.
The Journal of cell biology 1997;138(1):131-42.
-
1997: Yang B; van Hoek A N; Verkman A S
Very high single channel water permeability of aquaporin-4 in baculovirus-infected insect cells and liposomes reconstituted with purified aquaporin-4.
Biochemistry 1997;36(24):7625-32.
-
1997: Yang B; Verkman A S
Water and glycerol permeabilities of aquaporins 1-5 and MIP determined quantitatively by expression of epitope-tagged constructs in Xenopus oocytes.
The Journal of biological chemistry 1997;272(26):16140-6.
-
1997: Swaminathan R; Hoang C P; Verkman A S
Photobleaching recovery and anisotropy decay of green fluorescent protein GFP-S65T in solution and cells: cytoplasmic viscosity probed by green fluorescent protein translational and rotational diffusion.
Biophysical journal 1997;72(4):1900-7.
-
1996: Farinas J; Verkman A S
Cell volume and plasma membrane osmotic water permeability in epithelial cell layers measured by interferometry.
Biophysical journal 1996;71(6):3511-22.
-
1996: Ma T; Yang B; Verkman A S
cDNA cloning of a functional water channel from toad urinary bladder epithelium.
The American journal of physiology 1996;271(5 Pt 1):C1699-704.
-
1996: Umenishi F; Carter E P; Yang B; Oliver B; Matthay M A; Verkman A S
Sharp increase in rat lung water channel expression in the perinatal period.
American journal of respiratory cell and molecular biology 1996;15(5):673-9.
-
1996: Thevenin B J; Bicknese S E; Park J; Verkman A S; Shohet S B
Distance between Cys-201 in erythrocyte band 3 and the bilayer measured by single-photon radioluminescence.
Biophysical journal 1996;71(5):2645-55.
-
1996: Biwersi J; Emans N; Verkman A S
Cystic fibrosis transmembrane conductance regulator activation stimulates endosome fusion in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(22):12484-9.
-
1996: Carter E P; Matthay M A; Farinas J; Verkman A S
Transalveolar osmotic and diffusional water permeability in intact mouse lung measured by a novel surface fluorescence method.
The Journal of general physiology 1996;108(3):133-42.
-
1996: Townsend R R; Lipniunas P H; Tulk B M; Verkman A S
Identification of protein kinase A phosphorylation sites on NBD1 and R domains of CFTR using electrospray mass spectrometry with selective phosphate ion monitoring.
Protein science : a publication of the Protein Society 1996;5(9):1865-73.
-
1996: Swaminathan R; Bicknese S; Periasamy N; Verkman A S
Cytoplasmic viscosity near the cell plasma membrane: translational diffusion of a small fluorescent solute measured by total internal reflection-fluorescence photobleaching recovery.
Biophysical journal 1996;71(2):1140-51.
-
1996: Ma T; Yang B; Kuo W L; Verkman A S
cDNA cloning and gene structure of a novel water channel expressed exclusively in human kidney: evidence for a gene cluster of aquaporins at chromosome locus 12q13.
Genomics 1996;35(3):543-50.
-
1996: Emans N; Verkman A S
Real-time fluorescence measurement of cell-free endosome fusion: regulation by second messengers.
Biophysical journal 1996;71(1):487-94.
-
1996: Brown C R; Hong-Brown L Q; Biwersi J; Verkman A S; Welch W J
Chemical chaperones correct the mutant phenotype of the delta F508 cystic fibrosis transmembrane conductance regulator protein.
Cell stress & chaperones 1996;1(2):117-25.
-
1996: Umenishi F; Verkman A S; Gropper M A
Quantitative analysis of aquaporin mRNA expression in rat tissues by RNase protection assay.
DNA and cell biology 1996;15(6):475-80.
-
1996: Seksek O; Biwersi J; Verkman A S
Evidence against defective trans-Golgi acidification in cystic fibrosis.
The Journal of biological chemistry 1996;271(26):15542-8.
-
1996: Ma T; Yang B; Verkman A S
Gene structure, cDNA cloning, and expression of a mouse mercurial-insensitive water channel.
Genomics 1996;33(3):382-8.
-
1996: Matthay M A; Folkesson H G; Verkman A S
Salt and water transport across alveolar and distal airway epithelia in the adult lung.
The American journal of physiology 1996;270(4 Pt 1):L487-503.
-
1996: Periasamy N; Bicknese S; Verkman A S
Reversible photobleaching of fluorescein conjugates in air-saturated viscous solutions: singlet and triplet state quenching by tryptophan.
Photochemistry and photobiology 1996;63(3):265-71.
-
1996: Kao H P; Verkman A S
Construction and performance of a photobleaching recovery apparatus with microsecond time resolution.
Biophysical chemistry 1996;59(1-2):203-10.
-
1996: Yang B; Brown D; Verkman A S
The mercurial insensitive water channel (AQP-4) forms orthogonal arrays in stably transfected Chinese hamster ovary cells.
The Journal of biological chemistry 1996;271(9):4577-80.
-
1996: Folkesson H G; Matthay M A; Frigeri A; Verkman A S
Transepithelial water permeability in microperfused distal airways. Evidence for channel-mediated water transport.
The Journal of clinical investigation 1996;97(3):664-71.
-
1996: Verkman A S; van Hoek A N; Ma T; Frigeri A; Skach W R; Mitra A; Tamarappoo B K; Farinas J
Water transport across mammalian cell membranes.
The American journal of physiology 1996;270(1 Pt 1):C12-30.
-
1996: Shi L B; Verkman A S
Selected cysteine point mutations confer mercurial sensitivity to the mercurial-insensitive water channel MIWC/AQP-4.
Biochemistry 1996;35(2):538-44.
-
1995: Verkman A S
Optical methods to measure membrane transport processes.
The Journal of membrane biology 1995;148(2):99-110.
-
1995: Verkman A S; Shi L B; Frigeri A; Hasegawa H; Farinas J; Mitra A; Skach W; Brown D; Van Hoek A N; Ma T
Structure and function of kidney water channels.
Kidney international 1995;48(4):1069-81.
-
1995: Frigeri A; Gropper M A; Umenishi F; Kawashima M; Brown D; Verkman A S
Localization of MIWC and GLIP water channel homologs in neuromuscular, epithelial and glandular tissues.
Journal of cell science 1995;108 ( Pt 9)():2993-3002.
-
1995: Yang B; Ma T; Verkman A S
cDNA cloning, gene organization, and chromosomal localization of a human mercurial insensitive water channel. Evidence for distinct transcriptional units.
The Journal of biological chemistry 1995;270(39):22907-13.
-
1995: Emans N; Biwersi J; Verkman A S
Imaging of endosome fusion in BHK fibroblasts based on a novel fluorimetric avidin-biotin binding assay.
Biophysical journal 1995;69(2):716-28.
-
1995: Bicknese S; Rossi M; Thevenin B; Shohet S B; Verkman A S
Anisotropy decay measurement of segmental dynamics of the anion binding domain in erythrocyte band 3.
Biochemistry 1995;34(33):10645-51.
-
1995: Katsura T; Verbavatz J M; Farinas J; Ma T; Ausiello D A; Verkman A S; Brown D
Constitutive and regulated membrane expression of aquaporin 1 and aquaporin 2 water channels in stably transfected LLC-PK1 epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(16):7212-6.
-
1995: Brown D; Katsura T; Kawashima M; Verkman A S; Sabolic I
Cellular distribution of the aquaporins: a family of water channel proteins.
Histochemistry and cell biology 1995;104(1):1-9.
-
1995: Shi L B; Skach W R; Ma T; Verkman A S
Distinct biogenesis mechanisms for the water channels MIWC and CHIP28 at the endoplasmic reticulum.
Biochemistry 1995;34(26):8250-6.
-
1995: Bicknese S; Zimet D; Park J; van Hoek A N; Shohet S B; Verkman A S
Detection of water proximity to tryptophan residues in proteins by single photon radioluminescence.
Biophysical chemistry 1995;54(3):279-90.
-
1995: Frigeri A; Gropper M A; Turck C W; Verkman A S
Immunolocalization of the mercurial-insensitive water channel and glycerol intrinsic protein in epithelial cell plasma membranes.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(10):4328-31.
-
1995: Zimet D B; Thevenin B J; Verkman A S; Shohet S B; Abney J R
Calculation of resonance energy transfer in crowded biological membranes.
Biophysical journal 1995;68(4):1592-603.
-
1995: Farinas J; Simanek V; Verkman A S
Cell volume measured by total internal reflection microfluorimetry: application to water and solute transport in cells transfected with water channel homologs.
Biophysical journal 1995;68(4):1613-20.
-
1995: Seksek O; Biwersi J; Verkman A S
Direct measurement of trans-Golgi pH in living cells and regulation by second messengers.
The Journal of biological chemistry 1995;270(10):4967-70.
-
1995: van Hoek A N; Wiener M C; Verbavatz J M; Brown D; Lipniunas P H; Townsend R R; Verkman A S
Purification and structure-function analysis of native, PNGase F-treated, and endo-beta-galactosidase-treated CHIP28 water channels.
Biochemistry 1995;34(7):2212-9.
-
1994: Mitra A K; Yeager M; van Hoek A N; Wiener M C; Verkman A S
Projection structure of the CHIP28 water channel in lipid bilayer membranes at 12-A resolution.
Biochemistry 1994;33(43):12735-40.
-
1994: Kao H P; Verkman A S
Tracking of single fluorescent particles in three dimensions: use of cylindrical optics to encode particle position.
Biophysical journal 1994;67(3):1291-300.
-
1994: Valenti G; Verbavatz J M; Sabolic I; Ausiello D A; Verkman A S; Brown D
A basolateral CHIP28/MIP26-related protein (BLIP) in kidney principal cells and gastric parietal cells.
The American journal of physiology 1994;267(3 Pt 1):C812-20.
-
1994: Ma T; Frigeri A; Hasegawa H; Verkman A S
Cloning of a water channel homolog expressed in brain meningeal cells and kidney collecting duct that functions as a stilbene-sensitive glycerol transporter.
The Journal of biological chemistry 1994;269(34):21845-9.
-
1994: Biwersi J; Tulk B; Verkman A S
Long-wavelength chloride-sensitive fluorescent indicators.
Analytical biochemistry 1994;219(1):139-43.
-
1994: Folkesson H G; Matthay M A; Hasegawa H; Kheradmand F; Verkman A S
Transcellular water transport in lung alveolar epithelium through mercury-sensitive water channels.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(11):4970-4.
-
1994: Skach W R; Shi L B; Calayag M C; Frigeri A; Lingappa V R; Verkman A S
Biogenesis and transmembrane topology of the CHIP28 water channel at the endoplasmic reticulum.
The Journal of cell biology 1994;125(4):803-15.
-
1994: Verbavatz J M; Van Hoek A N; Ma T; Sabolic I; Valenti G; Ellisman M H; Ausiello D A; Verkman A S; Brown D
A 28 kDa sarcolemmal antigen in kidney principal cell basolateral membranes: relationship to orthogonal arrays and MIP26.
Journal of cell science 1994;107 ( Pt 4)():1083-94.
-
1994: Hasegawa H; Lian S C; Finkbeiner W E; Verkman A S
Extrarenal tissue distribution of CHIP28 water channels by in situ hybridization and antibody staining.
The American journal of physiology 1994;266(4 Pt 1):C893-903.
-
1994: Shi L B; Skach W R; Verkman A S
Functional independence of monomeric CHIP28 water channels revealed by expression of wild-type mutant heterodimers.
The Journal of biological chemistry 1994;269(14):10417-22.
-
1994: Thevenin B J; Periasamy N; Shohet S B; Verkman A S
Segmental dynamics of the cytoplasmic domain of erythrocyte band 3 determined by time-resolved fluorescence anisotropy: sensitivity to pH and ligand binding.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(5):1741-5.
-
1994: Hasegawa H; Ma T; Skach W; Matthay M A; Verkman A S
Molecular cloning of a mercurial-insensitive water channel expressed in selected water-transporting tissues.
The Journal of biological chemistry 1994;269(8):5497-500.
-
1994: Ma T; Hasegawa H; Skach W R; Frigeri A; Verkman A S
Expression, functional analysis, and in situ hybridization of a cloned rat kidney collecting duct water channel.
The American journal of physiology 1994;266(1 Pt 1):C189-97.
-
1994: Biwersi J; Verkman A S
Functional CFTR in endosomal compartment of CFTR-expressing fibroblasts and T84 cells.
The American journal of physiology 1994;266(1 Pt 1):C149-56.
-
1993: Ma T; Frigeri A; Skach W; Verkman A S
Cloning of a novel rat kidney cDNA homologous to CHIP28 and WCH-CD water channels.
Biochemical and biophysical research communications 1993;197(2):654-9.
-
1993: Farinas J; Van Hoek A N; Shi L B; Erickson C; Verkman A S
Nonpolar environment of tryptophans in erythrocyte water channel CHIP28 determined by fluorescence quenching.
Biochemistry 1993;32(44):11857-64.
-
1993: Van Hoek A N; Wiener M; Bicknese S; Miercke L; Biwersi J; Verkman A S
Secondary structure analysis of purified functional CHIP28 water channels by CD and FTIR spectroscopy.
Biochemistry 1993;32(44):11847-56.
-
1993: Verbavatz J M; Brown D; Sabolic I; Valenti G; Ausiello D A; Van Hoek A N; Ma T; Verkman A S
Tetrameric assembly of CHIP28 water channels in liposomes and cell membranes: a freeze-fracture study.
The Journal of cell biology 1993;123(3):605-18.
-
1993: Ma T; Frigeri A; Tsai S T; Verbavatz J M; Verkman A S
Localization and functional analysis of CHIP28k water channels in stably transfected Chinese hamster ovary cells.
The Journal of biological chemistry 1993;268(30):22756-64.
-
1993: Bicknese S; Periasamy N; Shohet S B; Verkman A S
Cytoplasmic viscosity near the cell plasma membrane: measurement by evanescent field frequency-domain microfluorimetry.
Biophysical journal 1993;65(3):1272-82.
-
1993: Hasegawa H; Verkman A S
Functional expression of cAMP-dependent and independent urea transporters in Xenopus oocytes.
The American journal of physiology 1993;265(2 Pt 1):C514-20.
-
1993: Zhang R; van Hoek A N; Biwersi J; Verkman A S
A point mutation at cysteine 189 blocks the water permeability of rat kidney water channel CHIP28k.
Biochemistry 1993;32(12):2938-41.
-
1993: Zhang R; Skach W; Hasegawa H; van Hoek A N; Verkman A S
Cloning, functional analysis and cell localization of a kidney proximal tubule water transporter homologous to CHIP28.
The Journal of cell biology 1993;120(2):359-69.
-
1993: Kao H P; Abney J R; Verkman A S
Determinants of the translational mobility of a small solute in cell cytoplasm.
The Journal of cell biology 1993;120(1):175-84.
-
1993: Hasegawa H; Zhang R; Dohrman A; Verkman A S
Tissue-specific expression of mRNA encoding rat kidney water channel CHIP28k by in situ hybridization.
The American journal of physiology 1993;264(1 Pt 1):C237-45.
-
1992: Sabolic I; Valenti G; Verbavatz J M; Van Hoek A N; Verkman A S; Ausiello D A; Brown D
Localization of the CHIP28 water channel in rat kidney.
The American journal of physiology 1992;263(6 Pt 1):C1225-33.
-
1992: Shahrokh Z; Bicknese S; Shohet S B; Verkman A S
Single photon radioluminescence. II. Signal detection and biological applications.
Biophysical journal 1992;63(5):1267-79.
-
1992: Bicknese S; Shahrokh Z; Shohet S B; Verkman A S
Single photon radioluminescence. I. Theory and spectroscopic properties.
Biophysical journal 1992;63(5):1256-66.
-
1992: Hasegawa H; Skach W; Baker O; Calayag M C; Lingappa V; Verkman A S
A multifunctional aqueous channel formed by CFTR.
Science (New York, N.Y.) 1992;258(5087):1477-9.
-
1992: Periasamy N; Kao H P; Fushimi K; Verkman A S
Organic osmolytes increase cytoplasmic viscosity in kidney cells.
The American journal of physiology 1992;263(4 Pt 1):C901-7.
-
1992: Sabolic I; Wuarin F; Shi L B; Verkman A S; Ausiello D A; Gluck S; Brown D
Apical endosomes isolated from kidney collecting duct principal cells lack subunits of the proton pumping ATPase.
The Journal of cell biology 1992;119(1):111-22.
-
1992: Zen K; Biwersi J; Periasamy N; Verkman A S
Second messengers regulate endosomal acidification in Swiss 3T3 fibroblasts.
The Journal of cell biology 1992;119(1):99-110.
-
1992: van Hoek A N; Verkman A S
Functional reconstitution of the isolated erythrocyte water channel CHIP28.
The Journal of biological chemistry 1992;267(26):18267-9.
-
1992: Echevarria M; Verkman A S
Optical measurement of osmotic water transport in cultured cells. Role of glucose transporters.
The Journal of general physiology 1992;99(4):573-89.
-
1992: Periasamy N; Verkman A S
Subtraction of background fluorescence in multiharmonic frequency-domain fluorimetry.
Analytical biochemistry 1992;201(1):107-13.
-
1992: Hartmann T; Kondo M; Mochizuki H; Verkman A S; Widdicombe J H
Calcium-dependent regulation of Cl secretion in tracheal epithelium.
The American journal of physiology 1992;262(2 Pt 1):L163-8.
-
1992: Hartmann T; Verkman A S
Construction and performance of a rapid scan monochromator for multiwavelength fluorimetry.
Analytical biochemistry 1992;200(1):139-42.
-
1992: Biwersi J; Farah N; Wang Y X; Ketcham R; Verkman A S
Synthesis of cell-impermeable Cl-sensitive fluorescent indicators with improved sensitivity and optical properties.
The American journal of physiology 1992;262(1 Pt 1):C242-50.
-
1992: Verkman A S; Chao A C; Hartmann T
Hormonal regulation of Cl transport in polar airway epithelia measured by a fluorescent indicator.
The American journal of physiology 1992;262(1 Pt 1):C23-31.
-
1992: Sabolic I; Shi L B; Brown D; Ausiello D A; Verkman A S
Proteinases inhibit H(+)-ATPase and Na+/H+ exchange but not water transport in apical and endosomal membranes from rat proximal tubule.
Biochimica et biophysica acta 1992;1103(1):137-47.
-
1992: Verkman A S
Water channels in cell membranes.
Annual review of physiology 1992;54():97-108.
-
1991: Periasamy N; Armijo M; Verkman A S
Picosecond rotation of small polar fluorophores in the cytosol of sea urchin eggs.
Biochemistry 1991;30(51):11836-41.
-
1991: Zhang R; Alper S L; Thorens B; Verkman A S
Evidence from oocyte expression that the erythrocyte water channel is distinct from band 3 and the glucose transporter.
The Journal of clinical investigation 1991;88(5):1553-8.
-
1991: Shi L B; Fushimi K; Verkman A S
Solvent drag measurement of transcellular and basolateral membrane NaCl reflection coefficient in kidney proximal tubule.
The Journal of general physiology 1991;98(2):379-98.
-
1991: Biwersi J; Verkman A S
Cell-permeable fluorescent indicator for cytosolic chloride.
Biochemistry 1991;30(32):7879-83.
-
1991: Kuwahara M; Shi L B; Marumo F; Verkman A S
Transcellular water flow modulates water channel exocytosis and endocytosis in kidney collecting tubule.
The Journal of clinical investigation 1991;88(2):423-9.
-
1991: Verkman A S; Shi L B; Bae H R; Fushimi K
Transport mechanisms in kidney proximal tubule examined using chloride-sensitive fluorescent indicators.
Kidney international. Supplement 1991;33():S103-8.
-
1991: Shahrokh Z; Verkman A S; Shohet S B
Distance between skeletal protein 4.1 and the erythrocyte membrane bilayer measured by resonance energy transfer.
The Journal of biological chemistry 1991;266(18):12082-9.
-
1991: Shi L B; Fushimi K; Bae H R; Verkman A S
Heterogeneity in ATP-dependent acidification in endocytic vesicles from kidney proximal tubule. Measurement of pH in individual endocytic vesicles in a cell-free system.
Biophysical journal 1991;59(6):1208-17.
-
1991: Verkman A S; Armijo M; Fushimi K
Construction and evaluation of a frequency-domain epifluorescence microscope for lifetime and anisotropy decay measurements in subcellular domains.
Biophysical chemistry 1991;40(1):117-25.
-
1991: Wang Y X; Shi L B; Verkman A S
Functional water channels and proton pumps are in separate populations of endocytic vesicles in toad bladder granular cells.
Biochemistry 1991;30(11):2888-94.
-
1991: Fushimi K; Verkman A S
Low viscosity in the aqueous domain of cell cytoplasm measured by picosecond polarization microfluorimetry.
The Journal of cell biology 1991;112(4):719-25.
-
1991: Tsai S T; Zhang R B; Verkman A S
High channel-mediated water permeability in rabbit erythrocytes: characterization in native cells and expression in Xenopus oocytes.
Biochemistry 1991;30(8):2087-92.
-
1991: Zhang R B; Verkman A S
Water and urea permeability properties of Xenopus oocytes: expression of mRNA from toad urinary bladder.
The American journal of physiology 1991;260(1 Pt 1):C26-34.
-
1991: Fushimi K; Verkman A S
Relationship between vasopressin-sensitive water transport and plasma membrane fluidity in kidney collecting tubule.
The American journal of physiology 1991;260(1 Pt 1):C1-8.
-
1990: Lencer W I; Brown D; Ausiello D A; Verkman A S
Endocytosis of water channels in rat kidney: cell specificity and correlation with in vivo antidiuresis.
The American journal of physiology 1990;259(6 Pt 1):C920-32.
-
1990: Bae H R; Verkman A S
Protein kinase A regulates chloride conductance in endocytic vesicles from proximal tubule.
Nature 1990;348(6302):637-9.
-
1990: Shi L B; Wang Y X; Verkman A S
Regulation of the formation and water permeability of endosomes from toad bladder granular cells.
The Journal of general physiology 1990;96(4):789-808.
-
1990: Zhang R B; Logee K A; Verkman A S
Expression of mRNA coding for kidney and red cell water channels in Xenopus oocytes.
The Journal of biological chemistry 1990;265(26):15375-8.
-
1990: Verkman A S
Development and biological applications of chloride-sensitive fluorescent indicators.
The American journal of physiology 1990;259(3 Pt 1):C375-88.
-
1990: Zhang R B; Verkman A S
Urea transport in freshly isolated and cultured cells from rat inner medullary collecting duct.
The Journal of membrane biology 1990;117(3):253-61.
-
1990: Hartmann T; Verkman A S
Model of ion transport regulation in chloride-secreting airway epithelial cells. Integrated description of electrical, chemical, and fluorescence measurements.
Biophysical journal 1990;58(2):391-401.
-
1990: Lencer W I; Verkman A S; Arnaout M A; Ausiello D A; Brown D
Endocytic vesicles from renal papilla which retrieve the vasopressin-sensitive water channel do not contain a functional H+ ATPase.
The Journal of cell biology 1990;111(2):379-89.
-
1990: Shi L B; Brown D; Verkman A S
Water, proton, and urea transport in toad bladder endosomes that contain the vasopressin-sensitive water channel.
The Journal of general physiology 1990;95(5):941-60.
-
1990: Roe J N; Szoka F C; Verkman A S
Fibre optic sensor for the detection of potassium using fluorescence energy transfer.
The Analyst 1990;115(4):353-8.
-
1990: Shi L B; Ye R G; Lencer W I; Verkman A S
[Characterization of proton pump and osmotic water transport in endocytic vesicles from rat kidney proximal tubule]
Sheng li xue bao : [Acta physiologica Sinica] 1990;42(2):105-13.
-
1990: Chao A C; Widdicombe J H; Verkman A S
Chloride conductive and cotransport mechanisms in cultures of canine tracheal epithelial cells measured by an entrapped fluorescent indicator.
The Journal of membrane biology 1990;113(3):193-202.
-
1990: Dix J A; Verkman A S
Pyrene eximer mapping in cultured fibroblasts by ratio imaging and time-resolved microscopy.
Biochemistry 1990;29(7):1949-53.
-
1990: Fushimi K; Dix J A; Verkman A S
Cell membrane fluidity in the intact kidney proximal tubule measured by orientation-independent fluorescence anisotropy imaging.
Biophysical journal 1990;57(2):241-54.
-
1990: Dix J A; Verkman A S
Mapping of fluorescence anisotropy in living cells by ratio imaging. Application to cytoplasmic viscosity.
Biophysical journal 1990;57(2):231-40.
-
1990: Lencer W I; Weyer P; Verkman A S; Ausiello D A; Brown D
FITC-dextran as a probe for endosome function and localization in kidney.
The American journal of physiology 1990;258(2 Pt 1):C309-17.
-
1989: Verkman A S; Weyer P; Brown D; Ausiello D A
Functional water channels are present in clathrin-coated vesicles from bovine kidney but not from brain.
The Journal of biological chemistry 1989;264(34):20608-13.
-
1989: Shi L B; Verkman A S
Very high water permeability in vasopressin-induced endocytic vesicles from toad urinary bladder.
The Journal of general physiology 1989;94(6):1101-15.
-
1989: Chao A C; Dix J A; Sellers M C; Verkman A S
Fluorescence measurement of chloride transport in monolayer cultured cells. Mechanisms of chloride transport in fibroblasts.
Biophysical journal 1989;56(6):1071-81.
-
1989: Verkman A S
Mechanisms and regulation of water permeability in renal epithelia.
The American journal of physiology 1989;257(5 Pt 1):C837-50.
-
1989: Kuwahara M; Verkman A S
Pre-steady-state analysis of the turn-on and turn-off of water permeability in the kidney collecting tubule.
The Journal of membrane biology 1989;110(1):57-65.
-
1989: Roe J N; Szoka F C; Verkman A S
Optical measurement of aqueous potassium concentration by a hydrophobic indicator in lipid vesicles.
Biophysical chemistry 1989;33(3):295-302.
-
1989: Pearce D; Verkman A S
NaCl reflection coefficients in proximal tubule apical and basolateral membrane vesicles. Measurement by induced osmosis and solvent drag.
Biophysical journal 1989;55(6):1251-9.
-
1989: Calafut T M; Dix J A; Verkman A S
Fluorescence depolarization of cis- and trans-parinaric acids in artificial and red cell membranes resolved by a double hindered rotational model.
Biochemistry 1989;28(12):5051-8.
-
1989: Verkman A S; Takla R; Sefton B; Basbaum C; Widdicombe J H
Quantitative fluorescence measurement of chloride transport mechanisms in phospholipid vesicles.
Biochemistry 1989;28(10):4240-4.
-
1989: Verkman A S; Sellers M C; Chao A C; Leung T; Ketcham R
Synthesis and characterization of improved chloride-sensitive fluorescent indicators for biological applications.
Analytical biochemistry 1989;178(2):355-61.
-
1989: Ye R G; Shi L B; Lencer W I; Verkman A S
Functional colocalization of water channels and proton pumps in endosomes from kidney proximal tubule.
The Journal of general physiology 1989;93(5):885-902.
-
1989: Ye R G; Verkman A S
Simultaneous optical measurement of osmotic and diffusional water permeability in cells and liposomes.
Biochemistry 1989;28(2):824-9.
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1988: Illsley N P; Glaubensklee C; Davis B; Verkman A S
Chloride transport across placental microvillous membranes measured by fluorescence.
The American journal of physiology 1988;255(6 Pt 1):C789-97.
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1988: Illsley N P; Goodman J G; Verkman A S; Davis B
Macromolecule entrapment in human placental microvillous membrane vesicles.
Analytical biochemistry 1988;175(1):106-13.
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1988: Kuwahara M; Berry C A; Verkman A S
Rapid development of vasopressin-induced hydroosmosis in kidney collecting tubules measured by a new fluorescence technique.
Biophysical journal 1988;54(4):595-602.
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1988: Kuwahara M; Verkman A S
Direct fluorescence measurement of diffusional water permeability in the vasopressin-sensitive kidney collecting tubule.
Biophysical journal 1988;54(4):587-93.
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1988: Berry C A; Verkman A S
Osmotic gradient dependence of osmotic water permeability in rabbit proximal convoluted tubule.
The Journal of membrane biology 1988;105(1):33-43.
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1988: Fong P; Illsley N P; Widdicombe J H; Verkman A S
Chloride transport in apical membrane vesicles from bovine tracheal epithelium: characterization using a fluorescent indicator.
The Journal of membrane biology 1988;104(3):233-9.
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1988: Verkman A S; Masur S K
Very low osmotic water permeability and membrane fluidity in isolated toad bladder granules.
The Journal of membrane biology 1988;104(3):241-51.
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1988: Kim Y K; Illsley N P; Verkman A S
Rapid fluorescence assay of glucose and neutral solute transport using an entrapped volume indicator.
Analytical biochemistry 1988;172(2):403-9.
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1988: Chen P Y; Pearce D; Verkman A S
Membrane water and solute permeability determined quantitatively by self-quenching of an entrapped fluorophore.
Biochemistry 1988;27(15):5713-8.
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1988: Krapf R; Berry C A; Verkman A S
Estimation of intracellular chloride activity in isolated perfused rabbit proximal convoluted tubules using a fluorescent indicator.
Biophysical journal 1988;53(6):955-62.
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1988: Verkman A S; Lencer W I; Brown D; Ausiello D A
Endosomes from kidney collecting tubule cells contain the vasopressin-sensitive water channel.
Nature 1988;333(6170):268-9.
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1988: Illsley N P; Lin H Y; Verkman A S
Lipid-phase structure in epithelial cell membranes: comparison of renal brush border and basolateral membranes.
Biochemistry 1988;27(6):2077-83.
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1988: Krapf R; Illsley N P; Tseng H C; Verkman A S
Structure-activity relationships of chloride-sensitive fluorescent indicators for biological application.
Analytical biochemistry 1988;169(1):142-50.
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1988: Chen P Y; Verkman A S
Sodium-dependent chloride transport in basolateral membrane vesicles isolated from rabbit proximal tubule.
Biochemistry 1988;27(2):655-60.
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1988: Chen P Y; Illsley N P; Verkman A S
Renal brush-border chloride transport mechanisms characterized using a fluorescent indicator.
The American journal of physiology 1988;254(1 Pt 2):F114-20.
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1987: Ausiello D A; Verkman A S; Skorecki K L
Vasopressin-sensitive adenylate cyclase: subunit interactions assessed by target analysis and computer modelling.
Kidney international. Supplement 1987;23():S43-55.
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1987: Verkman A S
Passive H+/OH- permeability in epithelial brush border membranes.
Journal of bioenergetics and biomembranes 1987;19(5):481-93.
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1987: Verkman A S
Mechanism and kinetics of merocyanine 540 binding to phospholipid membranes.
Biochemistry 1987;26(13):4050-6.
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1987: Chen P Y; Verkman A S
Renal basolateral membrane anion transporter characterized by a fluorescent disulfonic stilbene.
The Journal of membrane biology 1987;100(1):1-12.
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